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Search results 101 to 200 out of 2663 for Psen1

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Category: Publication
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Type Details Score
Publication
27425031 | J:255474
First Author: Kamphuis W
Year: 2016
Journal: Biochim Biophys Acta
Title: Transcriptional profiling of CD11c-positive microglia accumulating around amyloid plaques in a mouse model for Alzheimer's disease.
Volume: 1862
Issue: 10
Pages: 1847-60
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Publication
28855626 | J:255802
First Author: Baglietto-Vargas D
Year: 2017
Journal: Sci Rep
Title: Dual roles of Aβ in proliferative processes in an amyloidogenic model of Alzheimer's disease.
Volume: 7
Issue: 1
Pages: 10085
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Publication
25741723 | J:219929
First Author: Xia D
Year: 2015
Journal: Neuron
Title: Presenilin-1 knockin mice reveal loss-of-function mechanism for familial Alzheimer's disease.
Volume: 85
Issue: 5
Pages: 967-81
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Publication
9883847 | J:51950
First Author: Guo Q
Year: 1999
Journal: Nat Med
Title: Increased vulnerability of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knock-in mice.
Volume: 5
Issue: 1
Pages: 101-6
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Publication
10764737 | J:62820
First Author: Chan SL
Year: 2000
Journal: J Biol Chem
Title: Presenilin-1 mutations increase levels of ryanodine receptors and calcium release in PC12 cells and cortical neurons.
Volume: 275
Issue: 24
Pages: 18195-200
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Publication
12390529 | J:79892
First Author: Milhavet O
Year: 2002
Journal: J Neurochem
Title: Involvement of Gadd153 in the pathogenic action of presenilin-1 mutations.
Volume: 83
Issue: 3
Pages: 673-81
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Publication
18068871 | J:152964
First Author: Wang Y
Year: 2009
Journal: Neurobiol Aging
Title: Presenilin-1 mutation impairs cholinergic modulation of synaptic plasticity and suppresses NMDA currents in hippocampus slices.
Volume: 30
Issue: 7
Pages: 1061-8
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Publication
26455952 | J:232370
First Author: Kim S
Year: 2015
Journal: Neurobiol Aging
Title: Reduction of increased calcineurin activity rescues impaired homeostatic synaptic plasticity in presenilin 1 M146V mutant.
Volume: 36
Issue: 12
Pages: 3239-3246
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Publication
10526115 | J:57847
First Author: Zhu H
Year: 1999
Journal: Brain Res
Title: Dietary restriction protects hippocampal neurons against the death-promoting action of a presenilin-1 mutation.
Volume: 842
Issue: 1
Pages: 224-9
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Publication
14724250 | J:87452
First Author: Stutzmann GE
Year: 2004
Journal: J Neurosci
Title: Dysregulated IP3 signaling in cortical neurons of knock-in mice expressing an Alzheimer's-linked mutation in presenilin1 results in exaggerated Ca2+ signals and altered membrane excitability.
Volume: 24
Issue: 2
Pages: 508-13
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Publication
12064358 | J:106192
First Author: LaFontaine MA
Year: 2002
Journal: Neurochem Res
Title: Oxidative stress in synaptosomal proteins from mutant presenilin-1 knock-in mice: implications for familial Alzheimer's disease.
Volume: 27
Issue: 5
Pages: 417-21
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Publication
18205190 | J:156283
First Author: Wang G
Year: 2008
Journal: Glia
Title: Long-chain ceramide is elevated in presenilin 1 (PS1M146V) mouse brain and induces apoptosis in PS1 astrocytes.
Volume: 56
Issue: 4
Pages: 449-56
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Publication
23726841 | J:199100
First Author: Chu TH
Year: 2013
Journal: Cancer Lett
Title: miR-211 promotes the progression of head and neck carcinomas by targeting TGFβRII.
Volume: 337
Issue: 1
Pages: 115-24
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Publication
10811821 | J:62231
First Author: Leissring MA
Year: 2000
Journal: J Cell Biol
Title: Capacitative calcium entry deficits and elevated luminal calcium content in mutant presenilin-1 knockin mice.
Volume: 149
Issue: 4
Pages: 793-8
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Publication
10662826 | J:60290
First Author: Mattson MP
Year: 2000
Journal: J Neurosci
Title: Presenilin-1 mutation increases neuronal vulnerability to focal ischemia in vivo and to hypoxia and glucose deprivation in cell culture: involvement of perturbed calcium homeostasis.
Volume: 20
Issue: 4
Pages: 1358-64
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Publication
10097174 | J:54086
First Author: Guo Q
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Neurotrophic factors [activity-dependent neurotrophic factor (ADNF) and basic fibroblast growth factor (bFGF)] interrupt excitotoxic neurodegenerative cascades promoted by a PS1 mutation.
Volume: 96
Issue: 7
Pages: 4125-30
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Publication
11578614 | J:72044
First Author: Xie J
Year: 2001
Journal: Brain Res
Title: Aberrant induction of Par-4 is involved in apoptosis of hippocampal neurons in presenilin-1 M146V mutant knock-in mice.
Volume: 915
Issue: 1
Pages: 1-10
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Publication
10037473 | J:53132
First Author: Guo Q
Year: 1999
Journal: J Neurochem
Title: Increased vulnerability of hippocampal neurons from presenilin-1 mutant knock-in mice to amyloid beta-peptide toxicity: central roles of superoxide production and caspase activation.
Volume: 72
Issue: 3
Pages: 1019-29
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Publication
18466334 | J:139367
First Author: Malik B
Year: 2008
Journal: J Neurochem
Title: Cell cycle-driven neuronal apoptosis specifically linked to amyloid peptide Abeta1-42 exposure is not exacerbated in a mouse model of presenilin-1 familial Alzheimer's disease.
Volume: 106
Issue: 2
Pages: 912-6
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Publication
8986743 | J:83861
First Author: Citron M
Year: 1997
Journal: Nat Med
Title: Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid beta-protein in both transfected cells and transgenic mice.
Volume: 3
Issue: 1
Pages: 67-72
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Publication
10880403 | J:63138
First Author: Takeuchi A
Year: 2000
Journal: Am J Pathol
Title: Age-related amyloid beta deposition in transgenic mice overexpressing both Alzheimer mutant presenilin 1 and amyloid beta precursor protein Swedish mutant is not associated with global neuronal loss.
Volume: 157
Issue: 1
Pages: 331-9
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Publication
16307858 | J:128243
First Author: Wirths O
Year: 2006
Journal: Exp Gerontol
Title: Decreased plasma cholesterol levels during aging in transgenic mouse models of Alzheimer's disease.
Volume: 41
Issue: 2
Pages: 220-4
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38684238 | J:357877
First Author: Erkert L
Year: 2024
Journal: Gut
Title: Alzheimer's disease-related presenilins are key to intestinal epithelial cell function and gut immune homoeostasis.
Volume: 73
Issue: 10
Pages: 1618-1631
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18834536 | J:187802
 
First Author: Mirnics K
Year: 2008
Journal: Mol Neurodegener
Title: Molecular signatures of neurodegeneration in the cortex of PS1/PS2 double knockout mice.
Volume: 3
Pages: 14
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Publication
30201812 | J:266223
First Author: Tanaka Y
Year: 2018
Journal: J Immunol
Title: Presenilin 1 Regulates NF-κB Activation via Association with Breakpoint Cluster Region and Casein Kinase II.
Volume: 201
Issue: 8
Pages: 2256-2263
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22496554 | J:184454
First Author: Watanabe H
Year: 2012
Journal: J Neurosci
Title: Familial frontotemporal dementia-associated presenilin-1 c.548G>T mutation causes decreased mRNA expression and reduced presenilin function in knock-in mice.
Volume: 32
Issue: 15
Pages: 5085-96
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Publication
34329683 | J:312987
First Author: Sato K
Year: 2021
Journal: J Biol Chem
Title: A third-generation mouse model of Alzheimer's disease shows early and increased cored plaque pathology composed of wild-type human amyloid β peptide.
Volume: 297
Issue: 3
Pages: 101004
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Publication
10821758 | J:62163
First Author: Handler M
Year: 2000
Journal: Development
Title: Presenilin-1 regulates neuronal differentiation during neurogenesis.
Volume: 127
Issue: 12
Pages: 2593-606
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Publication
31577226 | J:290203
   
First Author: Javier-Torrent M
Year: 2019
Journal: Elife
Title: Presenilin/γ-secretase-dependent EphA3 processing mediates axon elongation through non-muscle myosin IIA.
Volume: 8
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Publication
20399254 | J:165240
First Author: Odero GL
Year: 2010
Journal: Neuroscience
Title: Evidence for the involvement of calbindin D28k in the presenilin 1 model of Alzheimer's disease.
Volume: 169
Issue: 1
Pages: 532-43
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Publication
17196556 | J:118185
First Author: Payette DJ
Year: 2007
Journal: Brain Res
Title: Reduction in CHT1-mediated choline uptake in primary neurons from presenilin-1 M146V mutant knock-in mice.
Volume: 1135
Issue: 1
Pages: 12-21
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Publication
19005074 | J:142399
First Author: Tamboli IY
Year: 2008
Journal: J Neurosci
Title: Loss of gamma-secretase function impairs endocytosis of lipoprotein particles and membrane cholesterol homeostasis.
Volume: 28
Issue: 46
Pages: 12097-106
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Publication
22311977 | J:316671
First Author: Shilling D
Year: 2012
Journal: J Biol Chem
Title: Lack of evidence for presenilins as endoplasmic reticulum Ca2+ leak channels.
Volume: 287
Issue: 14
Pages: 10933-44
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Publication
12460542 | J:125448
First Author: Chan SL
Year: 2002
Journal: Neurobiol Dis
Title: Presenilin-1 mutations sensitize neurons to DNA damage-induced death by a mechanism involving perturbed calcium homeostasis and activation of calpains and caspase-12.
Volume: 11
Issue: 1
Pages: 2-19
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11896164 | J:75588
First Author: Jantzen PT
Year: 2002
Journal: J Neurosci
Title: Microglial activation and beta -amyloid deposit reduction caused by a nitric oxide-releasing nonsteroidal anti-inflammatory drug in amyloid precursor protein plus presenilin-1 transgenic mice.
Volume: 22
Issue: 6
Pages: 2246-54
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Publication
11822882 | J:74751
First Author: Gordon MN
Year: 2002
Journal: Exp Neurol
Title: Time course of the development of Alzheimer-like pathology in the doubly transgenic PS1+APP mouse.
Volume: 173
Issue: 2
Pages: 183-95
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11520121 | J:71666
First Author: Kurt MA
Year: 2001
Journal: Exp Neurol
Title: Neurodegenerative changes associated with beta-amyloid deposition in the brains of mice carrying mutant amyloid precursor protein and mutant presenilin-1 transgenes.
Volume: 171
Issue: 1
Pages: 59-71
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Publication
9427614 | J:45724
First Author: Holcomb L
Year: 1998
Journal: Nat Med
Title: Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes.
Volume: 4
Issue: 1
Pages: 97-100
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11476589 | J:71061
First Author: Jaffar S
Year: 2001
Journal: Exp Neurol
Title: Neuropathology of mice carrying mutant APP(swe) and/or PS1(M146L) transgenes: alterations in the p75(NTR) cholinergic basal forebrain septohippocampal pathway.
Volume: 170
Issue: 2
Pages: 227-43
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11493021 | J:71187
First Author: Poduslo JF
Year: 2001
Journal: Neurobiol Dis
Title: Permeability of proteins at the blood-brain barrier in the normal adult mouse and double transgenic mouse model of Alzheimer's disease.
Volume: 8
Issue: 4
Pages: 555-67
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22393443 | J:185288
First Author: Trushina E
Year: 2012
Journal: PLoS One
Title: Defects in mitochondrial dynamics and metabolomic signatures of evolving energetic stress in mouse models of familial Alzheimer's disease.
Volume: 7
Issue: 2
Pages: e32737
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33255764 | J:305084
 
First Author: Kartalou GI
Year: 2020
Journal: Int J Mol Sci
Title: Anti-Inflammatory Treatment with FTY720 Starting after Onset of Symptoms Reverses Synaptic Deficits in an AD Mouse Model.
Volume: 21
Issue: 23
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20359773 | J:188249
First Author: Gengler S
Year: 2012
Journal: Neurobiol Aging
Title: Val(8)GLP-1 rescues synaptic plasticity and reduces dense core plaques in APP/PS1 mice.
Volume: 33
Issue: 2
Pages: 265-76
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Publication
15207348 | J:91277
First Author: Wang R
Year: 2004
Journal: Neuroscience
Title: Presenilin 1 familial Alzheimer's disease mutation leads to defective associative learning and impaired adult neurogenesis.
Volume: 126
Issue: 2
Pages: 305-12
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Publication
24145027 | J:209333
First Author: Almenar-Queralt A
Year: 2013
Journal: J Biol Chem
Title: Presenilins regulate neurotrypsin gene expression and neurotrypsin-dependent agrin cleavage via cyclic AMP response element-binding protein (CREB) modulation.
Volume: 288
Issue: 49
Pages: 35222-36
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30519973 | J:352127
First Author: Zhang H
Year: 2019
Journal: Angiogenesis
Title: Mouse models of Alzheimer's disease cause rarefaction of pial collaterals and increased severity of ischemic stroke.
Volume: 22
Issue: 2
Pages: 263-279
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33302995 | J:351231
First Author: Kang J
Year: 2020
Journal: Mol Neurodegener
Title: Cell-autonomous role of Presenilin in age-dependent survival of cortical interneurons.
Volume: 15
Issue: 1
Pages: 72
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28739891 | J:244685
First Author: Keskin AD
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: BACE inhibition-dependent repair of Alzheimer's pathophysiology.
Volume: 114
Issue: 32
Pages: 8631-8636
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12805290 | J:83886
First Author: Pigino G
Year: 2003
Journal: J Neurosci
Title: Alzheimer's presenilin 1 mutations impair kinesin-based axonal transport.
Volume: 23
Issue: 11
Pages: 4499-508
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17222948 | J:137684
First Author: Dewachter I
Year: 2008
Journal: Neurobiol Aging
Title: Modulation of synaptic plasticity and Tau phosphorylation by wild-type and mutant presenilin1.
Volume: 29
Issue: 5
Pages: 639-52
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10964951 | J:64209
First Author: Dewachter I
Year: 2000
Journal: J Neurosci
Title: Aging increased amyloid peptide and caused amyloid plaques in brain of old APP/V717I transgenic mice by a different mechanism than mutant presenilin1.
Volume: 20
Issue: 17
Pages: 6452-8
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16574645 | J:113453
First Author: Wang R
Year: 2006
Journal: J Biol Chem
Title: Wild-type presenilin 1 protects against Alzheimer disease mutation-induced amyloid pathology.
Volume: 281
Issue: 22
Pages: 15330-6
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8878479 | J:80861
First Author: Duff K
Year: 1996
Journal: Nature
Title: Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1.
Volume: 383
Issue: 6602
Pages: 710-3
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10037474 | J:53131
First Author: Begley JG
Year: 1999
Journal: J Neurochem
Title: Altered calcium homeostasis and mitochondrial dysfunction in cortical synaptic compartments of presenilin-1 mutant mice.
Volume: 72
Issue: 3
Pages: 1030-9
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38462606 | J:347713
First Author: Zhong MZ
Year: 2024
Journal: Mol Neurodegener
Title: Updates on mouse models of Alzheimer's disease.
Volume: 19
Issue: 1
Pages: 23
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21725313 | J:175901
First Author: Saito T
Year: 2011
Journal: Nat Neurosci
Title: Potent amyloidogenicity and pathogenicity of Aβ43.
Volume: 14
Issue: 8
Pages: 1023-32
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24103194 | J:206614
 
First Author: Hawkes CA
Year: 2013
Journal: Exp Neurol
Title: Stroke-induced opposite and age-dependent changes of vessel-associated markers in co-morbid transgenic mice with Alzheimer-like alterations.
Volume: 250
Pages: 270-81
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38187357 | J:344310
 
First Author: Wang H
Year: 2023
Journal: Front Aging Neurosci
Title: PKCε activator protects hippocampal microvascular disruption and memory defect in 3×Tg-Alzheimer's disease mice with cerebral microinfarcts.
Volume: 15
Pages: 1272361
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27875002 | J:350165
First Author: Tafoya MA
Year: 2017
Journal: J Magn Reson Imaging
Title: Superparamagnetic nanoparticle-enhanced MRI of Alzheimer's disease plaques and activated microglia in 3X transgenic mouse brains: Contrast optimization.
Volume: 46
Issue: 2
Pages: 574-588
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23486975 | J:196598
First Author: Ghosh S
Year: 2013
Journal: J Neurosci
Title: Sustained interleukin-1β overexpression exacerbates tau pathology despite reduced amyloid burden in an Alzheimer's mouse model.
Volume: 33
Issue: 11
Pages: 5053-64
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24316432 | J:210695
 
First Author: Song JM
Year: 2014
Journal: Exp Neurol
Title: A tetra(ethylene glycol) derivative of benzothiazole aniline ameliorates dendritic spine density and cognitive function in a mouse model of Alzheimer's disease.
Volume: 252
Pages: 105-13
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24268883 | J:212737
First Author: Rice RA
Year: 2014
Journal: Neurobiol Aging
Title: Age-related downregulation of the CaV3.1 T-type calcium channel as a mediator of amyloid beta production.
Volume: 35
Issue: 5
Pages: 1002-11
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17472708 | J:124130
First Author: Oddo S
Year: 2007
Journal: J Neurochem
Title: Genetically augmenting tau levels does not modulate the onset or progression of Abeta pathology in transgenic mice.
Volume: 102
Issue: 4
Pages: 1053-63
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25446741 | J:223868
 
First Author: Cañete T
Year: 2015
Journal: Behav Brain Res
Title: Cognitive and emotional alterations in young Alzheimer's disease (3xTgAD) mice: effects of neonatal handling stimulation and sexual dimorphism.
Volume: 281
Pages: 156-71
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23827221 | J:201677
 
First Author: Rodríguez JJ
Year: 2013
Journal: Neurosci Lett
Title: Increased densities of resting and activated microglia in the dentate gyrus follow senile plaque formation in the CA1 subfield of the hippocampus in the triple transgenic model of Alzheimer's disease.
Volume: 552
Pages: 129-34
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31055081 | J:283443
First Author: Fanaee-Danesh E
Year: 2019
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Astaxanthin exerts protective effects similar to bexarotene in Alzheimer's disease by modulating amyloid-beta and cholesterol homeostasis in blood-brain barrier endothelial cells.
Volume: 1865
Issue: 9
Pages: 2224-2245
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34896306 | J:319782
 
First Author: Nazari HK
Year: 2022
Journal: Exp Eye Res
Title: Age dependence of retinal vascular plexus attenuation in the triple transgenic mouse model of Alzheimer's disease.
Volume: 214
Pages: 108879
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28511979 | J:249623
 
First Author: Davis KE
Year: 2017
Journal: Behav Brain Res
Title: Water and T-maze protocols are equally efficient methods to assess spatial memory in 3xTg Alzheimer's disease mice.
Volume: 331
Pages: 54-66
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35095474 | J:319709
 
First Author: Liu J
Year: 2021
Journal: Front Aging Neurosci
Title: Preservation of Retinal Function Through Synaptic Stabilization in Alzheimer's Disease Model Mouse Retina by Lycium Barbarum Extracts.
Volume: 13
Pages: 788798
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26778963 | J:310589
 
First Author: Piedrahita D
Year: 2015
Journal: Front Cell Neurosci
Title: β-Secretase 1's Targeting Reduces Hyperphosphorilated Tau, Implying Autophagy Actors in 3xTg-AD Mice.
Volume: 9
Pages: 498
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24887583 | J:214748
 
First Author: Walls KC
Year: 2014
Journal: Neurosci Lett
Title: p-Tau immunotherapy reduces soluble and insoluble tau in aged 3xTg-AD mice.
Volume: 575
Pages: 96-100
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39424953 | J:359336
First Author: Xiong W
Year: 2024
Journal: EMBO J
Title: The mitochondrial long non-coding RNA lncMtloop regulates mitochondrial transcription and suppresses Alzheimer's disease.
Volume: 43
Issue: 23
Pages: 6001-6031
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22587890 | J:186440
 
First Author: Rosario ER
Year: 2012
Journal: Brain Res
Title: Evaluation of the effects of testosterone and luteinizing hormone on regulation of β-amyloid in male 3xTg-AD mice.
Volume: 1466
Pages: 137-45
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27777112 | J:350191
 
First Author: Schaeffer EL
Year: 2017
Journal: Ann Anat
Title: Stereological investigation of the CA1 pyramidal cell layer in untreated and lithium-treated 3xTg-AD and wild-type mice.
Volume: 209
Pages: 51-60
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37789692 | J:350208
First Author: Li J
Year: 2024
Journal: CNS Neurosci Ther
Title: Co-housing with Alzheimer's disease mice induces changes in gut microbiota and impairment of learning and memory in control mice.
Volume: 30
Issue: 4
Pages: e14491
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38510467 | J:348968
 
First Author: Medeiros D
Year: 2024
Journal: Front Neurosci
Title: Slowing Alzheimer's disease progression through probiotic supplementation.
Volume: 18
Pages: 1309075
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28911966 | J:249722
 
First Author: Sun DS
Year: 2017
Journal: Neuropharmacology
Title: Fluoxetine administration during adolescence attenuates cognitive and synaptic deficits in adult 3×TgAD mice.
Volume: 126
Pages: 200-212
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34798170 | J:322281
 
First Author: Yao L
Year: 2022
Journal: Behav Brain Res
Title: OGDHL ameliorates cognitive impairment and Alzheimer's disease-like pathology via activating Wnt/β-catenin signaling in Alzheimer's disease mice.
Volume: 418
Pages: 113673
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28740171 | J:249725
First Author: Durairajan SSK
Year: 2017
Journal: Sci Rep
Title: A modified formulation of Huanglian-Jie-Du-Tang reduces memory impairments and β-amyloid plaques in a triple transgenic mouse model of Alzheimer's disease.
Volume: 7
Issue: 1
Pages: 6238
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26939023 | J:249723
First Author: Makani V
Year: 2016
Journal: PLoS One
Title: BBB-Permeable, Neuroprotective, and Neurotrophic Polysaccharide, Midi-GAGR.
Volume: 11
Issue: 3
Pages: e0149715
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37392805 | J:348860
 
First Author: Falangola MF
Year: 2023
Journal: Magn Reson Imaging
Title: Quantitative microglia morphological features correlate with diffusion MRI in 2-month-old 3xTg-AD mice.
Volume: 103
Pages: 8-17
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22095718 | J:180375
First Author: Kitazawa M
Year: 2011
Journal: J Immunol
Title: Blocking IL-1 signaling rescues cognition, attenuates tau pathology, and restores neuronal β-catenin pathway function in an Alzheimer's disease model.
Volume: 187
Issue: 12
Pages: 6539-49
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36610154 | J:351248
 
First Author: He CL
Year: 2023
Journal: Phytomedicine
Title: Folium Hibisci Mutabilis extract, a potent autophagy enhancer, exhibits neuroprotective properties in multiple models of neurodegenerative diseases.
Volume: 109
Pages: 154548
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