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Search results 101 to 200 out of 1487 for Ptch1

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Category: Publication
Type Details Score
Publication  
First Author: Dakubo GD
Year: 2008
Journal: Brain Res
Title: Control of glial precursor cell development in the mouse optic nerve by sonic hedgehog from retinal ganglion cells.
Volume: 1228
Pages: 27-42
Publication
First Author: Tessier S
Year: 2019
Journal: Dev Biol
Title: NFAT5/TonEBP controls early acquisition of notochord phenotypic markers, collagen composition, and sonic hedgehog signaling during mouse intervertebral disc embryogenesis.
Volume: 455
Issue: 2
Pages: 369-381
Publication
First Author: Dennis JF
Year: 2012
Journal: PLoS Genet
Title: Mutations in Hedgehog acyltransferase (Hhat) perturb Hedgehog signaling, resulting in severe acrania-holoprosencephaly-agnathia craniofacial defects.
Volume: 8
Issue: 10
Pages: e1002927
Publication
First Author: Jeon S
Year: 2016
Journal: PLoS Genet
Title: Anteroposterior Limb Skeletal Patterning Requires the Bifunctional Action of SWI/SNF Chromatin Remodeling Complex in Hedgehog Pathway.
Volume: 12
Issue: 3
Pages: e1005915
Publication
First Author: Kumari A
Year: 2024
Journal: PLoS One
Title: Distinct expression patterns of Hedgehog signaling components in mouse gustatory system during postnatal tongue development and adult homeostasis.
Volume: 19
Issue: 6
Pages: e0294835
Publication
First Author: Liu HX
Year: 2013
Journal: Dev Biol
Title: Multiple Shh signaling centers participate in fungiform papilla and taste bud formation and maintenance.
Volume: 382
Issue: 1
Pages: 82-97
Publication
First Author: Carreno G
Year: 2017
Journal: Development
Title: Hypothalamic sonic hedgehog is required for cell specification and proliferation of LHX3/LHX4 pituitary embryonic precursors.
Volume: 144
Issue: 18
Pages: 3289-3302
Publication  
First Author: Matz-Soja M
Year: 2014
Journal: Cell Commun Signal
Title: Hepatic Hedgehog signaling contributes to the regulation of IGF1 and IGFBP1 serum levels.
Volume: 12
Pages: 11
Publication  
First Author: Veistinen LK
Year: 2017
Journal: Front Physiol
Title: Regulation of Calvarial Osteogenesis by Concomitant De-repression of GLI3 and Activation of IHH Targets.
Volume: 8
Pages: 1036
Publication  
First Author: Rosin JM
Year: 2015
Journal: BMC Neurosci
Title: Shox2 is required for the proper development of the facial motor nucleus and the establishment of the facial nerves.
Volume: 16
Pages: 39
Publication
First Author: Shimbo M
Year: 2017
Journal: PLoS One
Title: Postnatal lethality and chondrodysplasia in mice lacking both chondroitin sulfate N-acetylgalactosaminyltransferase-1 and -2.
Volume: 12
Issue: 12
Pages: e0190333
Publication  
First Author: Iulianella A
Year: 2019
Journal: Mech Dev
Title: The Hedgehog receptor Patched1 regulates proliferation, neurogenesis, and axon guidance in the embryonic spinal cord.
Volume: 160
Pages: 103577
Publication
First Author: Choi JJ
Year: 2014
Journal: PLoS One
Title: A role for smoothened during murine lens and cornea development.
Volume: 9
Issue: 9
Pages: e108037
Publication
First Author: D'Cruz R
Year: 2023
Journal: J Pathol
Title: Hedgehog signalling in Foxd1+ embryonic kidney stromal progenitors controls nephron formation via Cxcl12 and Wnt5a.
Volume: 261
Issue: 4
Pages: 385-400
Publication
First Author: Liu A
Year: 2005
Journal: Development
Title: Mouse intraflagellar transport proteins regulate both the activator and repressor functions of Gli transcription factors.
Volume: 132
Issue: 13
Pages: 3103-11
Publication
First Author: Nagao K
Year: 2005
Journal: Genomics
Title: Identification and characterization of multiple isoforms of a murine and human tumor suppressor, patched, having distinct first exons.
Volume: 85
Issue: 4
Pages: 462-71
Publication
First Author: Li Z
Year: 2008
Journal: Int J Biol Sci
Title: Reduced white fat mass in adult mice bearing a truncated Patched 1.
Volume: 4
Issue: 1
Pages: 29-36
Publication
First Author: Caty V
Year: 2006
Journal: Br J Dermatol
Title: Multiple large surface photodynamic therapy sessions with topical methylaminolaevulinate in PTCH heterozygous mice.
Volume: 154
Issue: 4
Pages: 740-2
Publication
First Author: Wetmore C
Year: 2000
Journal: Cancer Res
Title: The normal patched allele is expressed in medulloblastomas from mice with heterozygous germ-line mutation of patched.
Volume: 60
Issue: 8
Pages: 2239-46
Publication
First Author: Hamed S
Year: 2004
Journal: Cancer Res
Title: Accelerated induction of bladder cancer in patched heterozygous mutant mice.
Volume: 64
Issue: 6
Pages: 1938-42
Publication
First Author: Becher OJ
Year: 2008
Journal: Cancer Res
Title: Gli activity correlates with tumor grade in platelet-derived growth factor-induced gliomas.
Volume: 68
Issue: 7
Pages: 2241-9
Publication
First Author: Tang X
Year: 2004
Journal: J Clin Invest
Title: Ornithine decarboxylase is a target for chemoprevention of basal and squamous cell carcinomas in Ptch1+/- mice.
Volume: 113
Issue: 6
Pages: 867-75
Publication
First Author: Corcoran RB
Year: 2001
Journal: J Neurooncol
Title: A mouse model for medulloblastoma and basal cell nevus syndrome.
Volume: 53
Issue: 3
Pages: 307-18
Publication
First Author: Zhao X
Year: 2015
Journal: Cancer Res
Title: RAS/MAPK Activation Drives Resistance to Smo Inhibition, Metastasis, and Tumor Evolution in Shh Pathway-Dependent Tumors.
Volume: 75
Issue: 17
Pages: 3623-35
Publication
First Author: Mao J
Year: 2006
Journal: Cancer Res
Title: A novel somatic mouse model to survey tumorigenic potential applied to the Hedgehog pathway.
Volume: 66
Issue: 20
Pages: 10171-8
Publication
First Author: Lin AC
Year: 2009
Journal: Nat Med
Title: Modulating hedgehog signaling can attenuate the severity of osteoarthritis.
Volume: 15
Issue: 12
Pages: 1421-5
Publication
First Author: Lee EY
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Hedgehog pathway-regulated gene networks in cerebellum development and tumorigenesis.
Volume: 107
Issue: 21
Pages: 9736-41
Publication
First Author: Omenetti A
Year: 2008
Journal: J Clin Invest
Title: Hedgehog signaling regulates epithelial-mesenchymal transition during biliary fibrosis in rodents and humans.
Volume: 118
Issue: 10
Pages: 3331-42
Publication
First Author: Li L
Year: 2003
Journal: Cancer Res
Title: Mouse embryos cloned from brain tumors.
Volume: 63
Issue: 11
Pages: 2733-6
Publication
First Author: Liu Y
Year: 2017
Journal: Cancer Res
Title: Astrocytes Promote Medulloblastoma Progression through Hedgehog Secretion.
Volume: 77
Issue: 23
Pages: 6692-6703
Publication
First Author: Sengupta R
Year: 2012
Journal: Cancer Res
Title: CXCR4 activation defines a new subgroup of Sonic hedgehog-driven medulloblastoma.
Volume: 72
Issue: 1
Pages: 122-32
Publication
First Author: De Bortoli M
Year: 2007
Journal: Eur J Cancer
Title: Patched haploinsufficient mouse rhabdomyosarcoma overexpress secreted phosphoprotein 1 and matrix metalloproteinases.
Volume: 43
Issue: 8
Pages: 1308-17
Publication
First Author: Singh N
Year: 2015
Journal: Dis Model Mech
Title: Acute upregulation of hedgehog signaling in mice causes differential effects on cranial morphology.
Volume: 8
Issue: 3
Pages: 271-9
Publication
First Author: Chaudhary SC
Year: 2015
Journal: Oncotarget
Title: Shh and p50/Bcl3 signaling crosstalk drives pathogenesis of BCCs in Gorlin syndrome.
Volume: 6
Issue: 34
Pages: 36789-814
Publication
First Author: Aszterbaum M
Year: 1999
Journal: Nat Med
Title: Ultraviolet and ionizing radiation enhance the growth of BCCs and trichoblastomas in patched heterozygous knockout mice.
Volume: 5
Issue: 11
Pages: 1285-91
Publication
First Author: Küchler J
Year: 2011
Journal: Int J Cancer
Title: p75(NTR) induces apoptosis in medulloblastoma cells.
Volume: 128
Issue: 8
Pages: 1804-12
Publication  
First Author: Ballester A
Year: 2022
Journal: Int J Mol Sci
Title: Hedgehog Signalling Modulates Immune Response and Protects against Experimental Autoimmune Encephalomyelitis.
Volume: 23
Issue: 6
Publication
First Author: Moore SJ
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Engineered knottin peptide enables noninvasive optical imaging of intracranial medulloblastoma.
Volume: 110
Issue: 36
Pages: 14598-603
Publication
First Author: Pazzaglia S
Year: 2006
Journal: Cancer Lett
Title: Ptc1 heterozygous knockout mice as a model of multi-organ tumorigenesis.
Volume: 234
Issue: 2
Pages: 124-34
Publication
First Author: Faria CC
Year: 2015
Journal: Cancer Res
Title: Foretinib is effective therapy for metastatic sonic hedgehog medulloblastoma.
Volume: 75
Issue: 1
Pages: 134-46
Publication
First Author: Oliver TG
Year: 2005
Journal: Development
Title: Loss of patched and disruption of granule cell development in a pre-neoplastic stage of medulloblastoma.
Volume: 132
Issue: 10
Pages: 2425-39
Publication  
First Author: Dutka T
Year: 2015
Journal: Mech Dev
Title: Chronic up-regulation of the SHH pathway normalizes some developmental effects of trisomy in Ts65Dn mice.
Volume: 135
Pages: 68-80
Publication
First Author: Moshiri A
Year: 2004
Journal: J Neurosci
Title: Persistent progenitors at the retinal margin of ptc+/- mice.
Volume: 24
Issue: 1
Pages: 229-37
Publication
First Author: Wong SY
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Wounding mobilizes hair follicle stem cells to form tumors.
Volume: 108
Issue: 10
Pages: 4093-8
Publication
First Author: Vogt A
Year: 2005
Journal: J Invest Dermatol
Title: Anti-rejection drug treatment increases basal cell carcinoma burden in Ptch1+/- mice.
Volume: 124
Issue: 1
Pages: 263-7
Publication    
First Author: Ren YA
Year: 2019
Journal: JCI Insight
Title: S100a4-Cre-mediated deletion of Patched1 causes hypogonadotropic hypogonadism: role of pituitary hematopoietic cells in endocrine regulation.
Volume: 5
Publication
First Author: Hebert JL
Year: 2001
Journal: Skin Pharmacol Appl Skin Physiol
Title: Chemoprevention of basal cell carcinomas in the ptc1+/- mouse--green and black tea.
Volume: 14
Issue: 6
Pages: 358-62
Publication
First Author: Yao HH
Year: 2002
Journal: Dev Biol
Title: Disruption of testis cords by cyclopamine or forskolin reveals independent cellular pathways in testis organogenesis.
Volume: 246
Issue: 2
Pages: 356-65
Publication
First Author: Paudel S
Year: 2022
Journal: Carcinogenesis
Title: Chemopreventive efficacy of silibinin against basal cell carcinoma growth and progression in UVB-irradiated Ptch+/- mice.
Volume: 43
Issue: 6
Pages: 557-570
Publication
First Author: Zurawel RH
Year: 2000
Journal: Genes Chromosomes Cancer
Title: Evidence that haploinsufficiency of Ptch leads to medulloblastoma in mice.
Volume: 28
Issue: 1
Pages: 77-81
Publication
First Author: Markant SL
Year: 2013
Journal: Cancer Res
Title: Targeting sonic hedgehog-associated medulloblastoma through inhibition of Aurora and Polo-like kinases.
Volume: 73
Issue: 20
Pages: 6310-22
Publication
First Author: Li B
Year: 2014
Journal: Cancer Res
Title: Pyrvinium attenuates Hedgehog signaling downstream of smoothened.
Volume: 74
Issue: 17
Pages: 4811-21
Publication  
First Author: Lastowska M
Year: 2013
Journal: Acta Neuropathol Commun
Title: Identification of a neuronal transcription factor network involved in medulloblastoma development.
Volume: 1
Pages: 35
Publication
First Author: Lee JL
Year: 2005
Journal: J Invest Dermatol
Title: Differential expression of E prostanoid receptors in murine and human non-melanoma skin cancer.
Volume: 125
Issue: 4
Pages: 818-25
Publication
First Author: Black GC
Year: 2003
Journal: Hum Mol Genet
Title: Abnormalities of the vitreoretinal interface caused by dysregulated Hedgehog signaling during retinal development.
Volume: 12
Issue: 24
Pages: 3269-76
Publication  
First Author: Antonelli F
Year: 2018
Journal: Front Mol Neurosci
Title: Alterations in Morphology and Adult Neurogenesis in the Dentate Gyrus of Patched1 Heterozygous Mice.
Volume: 11
Pages: 168
Publication
First Author: Mancuso M
Year: 2011
Journal: Cancer Lett
Title: The estrogen receptor beta agonist diarylpropionitrile (DPN) inhibits medulloblastoma development via anti-proliferative and pro-apototic pathways.
Volume: 308
Issue: 2
Pages: 197-202
Publication  
First Author: Brandes N
Year: 2020
Journal: Int J Mol Sci
Title: Spreading of Isolated Ptch Mutant Basal Cell Carcinoma Precursors Is Physiologically Suppressed and Counteracts Tumor Formation in Mice.
Volume: 21
Issue: 23
Publication
First Author: Mancuso M
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Oncogenic bystander radiation effects in Patched heterozygous mouse cerebellum.
Volume: 105
Issue: 34
Pages: 12445-50
Publication
First Author: Mancuso M
Year: 2006
Journal: Cancer Res
Title: Hair cycle-dependent basal cell carcinoma tumorigenesis in Ptc1neo67/+ mice exposed to radiation.
Volume: 66
Issue: 13
Pages: 6606-14
Publication
First Author: Mancuso M
Year: 2009
Journal: Carcinogenesis
Title: Modulation of basal and squamous cell carcinoma by endogenous estrogen in mouse models of skin cancer.
Volume: 30
Issue: 2
Pages: 340-7
Publication
First Author: Presutti D
Year: 2018
Journal: PLoS One
Title: Tis21-gene therapy inhibits medulloblastoma growth in a murine allograft model.
Volume: 13
Issue: 3
Pages: e0194206
Publication
First Author: Pazzaglia S
Year: 2002
Journal: Oncogene
Title: High incidence of medulloblastoma following X-ray-irradiation of newborn Ptc1 heterozygous mice.
Volume: 21
Issue: 49
Pages: 7580-4
Publication
First Author: Pazzaglia S
Year: 2006
Journal: Oncogene
Title: Two-hit model for progression of medulloblastoma preneoplasia in Patched heterozygous mice.
Volume: 25
Issue: 40
Pages: 5575-80
Publication
First Author: Mancuso M
Year: 2010
Journal: Int J Cancer
Title: Protective role of 17 β-estradiol on medulloblastoma development in Patched 1 heterozygous mice.
Volume: 127
Issue: 12
Pages: 2749-57
Publication
First Author: Calzada-Wack J
Year: 2002
Journal: Carcinogenesis
Title: Unbalanced overexpression of the mutant allele in murine Patched mutants.
Volume: 23
Issue: 5
Pages: 727-33
Publication
First Author: Saran A
Year: 2007
Journal: Radiat Res
Title: Effects of exposure of newborn patched1 heterozygous mice to GSM, 900 MHz.
Volume: 168
Issue: 6
Pages: 733-40
Publication
First Author: Yang ZJ
Year: 2008
Journal: Cancer Cell
Title: Medulloblastoma can be initiated by deletion of Patched in lineage-restricted progenitors or stem cells.
Volume: 14
Issue: 2
Pages: 135-45
Publication
First Author: Zibat A
Year: 2009
Journal: Carcinogenesis
Title: Time-point and dosage of gene inactivation determine the tumor spectrum in conditional Ptch knockouts.
Volume: 30
Issue: 6
Pages: 918-26
Publication
First Author: Kimi K
Year: 2003
Journal: J Oral Pathol Med
Title: Immunohistochemical and genetic analysis of mandibular cysts in heterozygous ptc knockout mice.
Volume: 32
Issue: 2
Pages: 108-13
Publication
First Author: Nitzki F
Year: 2010
Journal: Cancer Res
Title: Tumor stroma-derived Wnt5a induces differentiation of basal cell carcinoma of Ptch-mutant mice via CaMKII.
Volume: 70
Issue: 7
Pages: 2739-48
Publication
First Author: Fan Q
Year: 2011
Journal: Chin J Cancer
Title: Tumor shrinkage by cyclopamine tartrate through inhibiting hedgehog signaling.
Volume: 30
Issue: 7
Pages: 472-81
Publication
First Author: Uhmann A
Year: 2007
Journal: Blood
Title: The Hedgehog receptor Patched controls lymphoid lineage commitment.
Volume: 110
Issue: 6
Pages: 1814-23
Publication
First Author: Uhmann A
Year: 2014
Journal: J Invest Dermatol
Title: DMBA/TPA treatment is necessary for BCC formation from patched deficient epidermal cells in Ptch(flox/flox)CD4Cre(+/-) mice.
Volume: 134
Issue: 10
Pages: 2620-2629
Publication
First Author: Michel KD
Year: 2013
Journal: PLoS One
Title: The hedgehog receptor patched1 in T cells is dispensable for adaptive immunity in mice.
Volume: 8
Issue: 4
Pages: e61034
Publication
First Author: Zhang X
Year: 2017
Journal: Cell Death Differ
Title: Hedgehog signaling in bone regulates whole-body energy metabolism through a bone-adipose endocrine relay mediated by PTHrP and adiponectin.
Volume: 24
Issue: 2
Pages: 225-237
Publication
First Author: Roy E
Year: 2020
Journal: Cell Rep
Title: Regional Variation in Epidermal Susceptibility to UV-Induced Carcinogenesis Reflects Proliferative Activity of Epidermal Progenitors.
Volume: 31
Issue: 9
Pages: 107702
Publication
First Author: Wong HY
Year: 2021
Journal: STAR Protoc
Title: Whole-mount staining coupled to a UV-inducible basal cell carcinoma murine model.
Volume: 2
Issue: 1
Pages: 100329
Publication
First Author: Grund-Gröschke S
Year: 2020
Journal: Mol Oncol
Title: Epidermal activation of Hedgehog signaling establishes an immunosuppressive microenvironment in basal cell carcinoma by modulating skin immunity.
Volume: 14
Issue: 9
Pages: 1930-1946
Publication
First Author: Ellis T
Year: 2003
Journal: Genesis
Title: Patched 1 conditional null allele in mice.
Volume: 36
Issue: 3
Pages: 158-61
Publication
First Author: Di Magno L
Year: 2020
Journal: Cell Rep
Title: Phenformin Inhibits Hedgehog-Dependent Tumor Growth through a Complex I-Independent Redox/Corepressor Module.
Volume: 30
Issue: 6
Pages: 1735-1752.e7
Publication
First Author: Lee MJ
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Hedgehog pathway inhibitor saridegib (IPI-926) increases lifespan in a mouse medulloblastoma model.
Volume: 109
Issue: 20
Pages: 7859-64
Publication
First Author: Hovestadt V
Year: 2014
Journal: Nature
Title: Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing.
Volume: 510
Issue: 7506
Pages: 537-41
Publication
First Author: Fuchs C
Year: 2012
Journal: Lab Invest
Title: Early-occurring proliferation defects in peripheral tissues of the Ts65Dn mouse model of Down syndrome are associated with patched1 over expression.
Volume: 92
Issue: 11
Pages: 1648-60
Publication
First Author: Morrissy AS
Year: 2016
Journal: Nature
Title: Divergent clonal selection dominates medulloblastoma at recurrence.
Volume: 529
Issue: 7586
Pages: 351-7
Publication  
First Author: Pyczek J
Year: 2016
Journal: Sci Rep
Title: Hedgehog signaling activation induces stem cell proliferation and hormone release in the adult pituitary gland.
Volume: 6
Pages: 24928
Publication
First Author: König S
Year: 2014
Journal: PLoS One
Title: Depletion of cutaneous macrophages and dendritic cells promotes growth of basal cell carcinoma in mice.
Volume: 9
Issue: 4
Pages: e93555
Publication  
First Author: Pyczek J
Year: 2019
Journal: Front Genet
Title: Regulation and Role of GLI1 in Cutaneous Squamous Cell Carcinoma Pathogenesis.
Volume: 10
Pages: 1185
Publication
First Author: Skop AR
Year: 2004
Journal: Science
Title: Dissection of the mammalian midbody proteome reveals conserved cytokinesis mechanisms.
Volume: 305
Issue: 5680
Pages: 61-6
Publication  
First Author: Wechsler-Reya R
Year: 2001
Journal: Annu Rev Neurosci
Title: The developmental biology of brain tumors.
Volume: 24
Pages: 385-428
Publication
First Author: Wicking C
Year: 1999
Journal: Oncogene
Title: The hedgehog signalling pathway in tumorigenesis and development.
Volume: 18
Issue: 55
Pages: 7844-51
Publication
First Author: Hahn H
Year: 1996
Journal: Cell
Title: Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome.
Volume: 85
Issue: 6
Pages: 841-51
Publication
First Author: Hahn H
Year: 1999
Journal: J Mol Med (Berl)
Title: The patched signaling pathway in tumorigenesis and development: lessons from animal models.
Volume: 77
Issue: 6
Pages: 459-68
Publication
First Author: Uchikawa H
Year: 2006
Journal: Biochem Biophys Res Commun
Title: Brain- and heart-specific Patched-1 containing exon 12b is a dominant negative isoform and is expressed in medulloblastomas.
Volume: 349
Issue: 1
Pages: 277-83
Publication  
First Author: Johnson BP
Year: 2021
Journal: Front Cell Dev Biol
Title: A Microphysiological Approach to Evaluate Effectors of Intercellular Hedgehog Signaling in Development.
Volume: 9
Pages: 621442
Publication  
First Author: Surolia R
Year: 2021
Journal: JCI Insight
Title: NETosis in the pathogenesis of acute lung injury following cutaneous chemical burns.
Volume: 6
Issue: 10
Publication
First Author: Pelczar P
Year: 2013
Journal: Gastroenterology
Title: Inactivation of Patched1 in mice leads to development of gastrointestinal stromal-like tumors that express Pdgfrα but not kit.
Volume: 144
Issue: 1
Pages: 134-144.e6
Publication
First Author: Marazziti D
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Precocious cerebellum development and improved motor functions in mice lacking the astrocyte cilium-, patched 1-associated Gpr37l1 receptor.
Volume: 110
Issue: 41
Pages: 16486-91
Publication
First Author: Ma G
Year: 2011
Journal: Cell Res
Title: Indian hedgehog mutations causing brachydactyly type A1 impair Hedgehog signal transduction at multiple levels.
Volume: 21
Issue: 9
Pages: 1343-57
Publication
First Author: Li C
Year: 2016
Journal: Am J Pathol
Title: Molecular Mechanism Underlying Pathogenesis of Lewisite-Induced Cutaneous Blistering and Inflammation: Chemical Chaperones as Potential Novel Antidotes.
Volume: 186
Issue: 10
Pages: 2637-49