|  Help  |  About  |  Contact Us

Search our database by keyword

- or -

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 101 to 200 out of 348 for Vhl

Category restricted to Publication (x)

<< First    < Previous  |  Next >    Last >>
0.045s

Categories

Category: Publication
« show all
Type Details Score
Publication
16537898 | J:106926
First Author: Tang N
Year: 2006
Journal: Mol Cell Biol
Title: pVHL function is essential for endothelial extracellular matrix deposition.
Volume: 26
Issue: 7
Pages: 2519-30
•
•
•
•
•
Publication
17203215 | J:123030
First Author: Park SK
Year: 2007
Journal: Int J Oncol
Title: von Hippel Lindau tumor suppressor regulates hepatic glucose metabolism by controlling expression of glucose transporter 2 and glucose 6-phosphatase.
Volume: 30
Issue: 2
Pages: 341-8
•
•
•
•
•
Publication
26398496 | J:236849
First Author: Gerl K
Year: 2015
Journal: Kidney Int
Title: Inducible glomerular erythropoietin production in the adult kidney.
Volume: 88
Issue: 6
Pages: 1345-1355
•
•
•
•
•
Publication
16510575 | J:106705
First Author: Rankin EB
Year: 2006
Journal: Cancer Res
Title: Renal cyst development in mice with conditional inactivation of the von Hippel-Lindau tumor suppressor.
Volume: 66
Issue: 5
Pages: 2576-83
•
•
•
•
•
Publication
34556788 | J:312362
First Author: Todd VM
Year: 2021
Journal: Commun Biol
Title: Hypoxia inducible factor signaling in breast tumors controls spontaneous tumor dissemination in a site-specific manner.
Volume: 4
Issue: 1
Pages: 1122
•
•
•
•
•
Publication
24940620 | J:218958
First Author: Zhang LF
Year: 2014
Journal: PLoS One
Title: Osteoblast-secreted factors promote proliferation and osteogenic differentiation of bone marrow stromal cells via VEGF/heme-oxygenase-1 pathway.
Volume: 9
Issue: 6
Pages: e99946
•
•
•
•
•
Publication
26348575 | J:226906
First Author: Mangiavini L
Year: 2015
Journal: Am J Pathol
Title: Fibrosis and hypoxia-inducible factor-1α-dependent tumors of the soft tissue on loss of von Hippel-Lindau in mesenchymal progenitors.
Volume: 185
Issue: 11
Pages: 3090-101
•
•
•
•
•
Publication
20197624 | J:158732
First Author: Hickey MM
Year: 2010
Journal: J Clin Invest
Title: The von Hippel-Lindau Chuvash mutation promotes pulmonary hypertension and fibrosis in mice.
Volume: 120
Issue: 3
Pages: 827-39
•
•
•
•
•
Publication
31613797 | J:298369
 
First Author: Wei R
Year: 2019
Journal: JCI Insight
Title: Rb1/Rbl1/Vhl loss induces mouse subretinal angiomatous proliferation and hemangioblastoma.
Volume: 4
Issue: 22
•
•
•
•
•
Publication
31181196 | J:280347
 
First Author: Schori C
Year: 2019
Journal: Exp Eye Res
Title: A chronic hypoxic response in photoreceptors alters the vitreous proteome in mice.
Volume: 185
Pages: 107690
•
•
•
•
•
Publication
22419665 | J:185744
First Author: Xue X
Year: 2012
Journal: Cancer Res
Title: Hypoxia-inducible factor-2α activation promotes colorectal cancer progression by dysregulating iron homeostasis.
Volume: 72
Issue: 9
Pages: 2285-93
•
•
•
•
•
Publication
32807776 | J:303341
First Author: Hoefflin R
Year: 2020
Journal: Nat Commun
Title: HIF-1α and HIF-2α differently regulate tumour development and inflammation of clear cell renal cell carcinoma in mice.
Volume: 11
Issue: 1
Pages: 4111
•
•
•
•
•
Publication
26759234 | J:231634
First Author: Schönenberger D
Year: 2016
Journal: Cancer Res
Title: Formation of Renal Cysts and Tumors in Vhl/Trp53-Deficient Mice Requires HIF1α and HIF2α.
Volume: 76
Issue: 7
Pages: 2025-36
•
•
•
•
•
Publication
18439915 | J:136664
First Author: Shah YM
Year: 2008
Journal: Gastroenterology
Title: Hypoxia-inducible factor augments experimental colitis through an MIF-dependent inflammatory signaling cascade.
Volume: 134
Issue: 7
Pages: 2036-48, 2048.e1-3
•
•
•
•
•
Publication
22150821 | J:196860
First Author: Zhang J
Year: 2012
Journal: Clin Exp Pharmacol Physiol
Title: Hypoxia-inducible factor 1 activation from adipose protein 2-cre mediated knockout of von Hippel-Lindau gene leads to embryonic lethality.
Volume: 39
Issue: 2
Pages: 145-50
•
•
•
•
•
Publication
21447692 | J:181428
First Author: Lange C
Year: 2011
Journal: Invest Ophthalmol Vis Sci
Title: Normoxic activation of hypoxia-inducible factors in photoreceptors provides transient protection against light-induced retinal degeneration.
Volume: 52
Issue: 8
Pages: 5872-80
•
•
•
•
•
Publication
18285456 | J:136012
First Author: Lei L
Year: 2008
Journal: Mol Cell Biol
Title: Hypoxia-inducible factor-dependent degeneration, failure, and malignant transformation of the heart in the absence of the von Hippel-Lindau protein.
Volume: 28
Issue: 11
Pages: 3790-803
•
•
•
•
•
Publication
15798202 | J:97652
First Author: Rankin EB
Year: 2005
Journal: Mol Cell Biol
Title: Inactivation of the arylhydrocarbon receptor nuclear translocator (Arnt) suppresses von Hippel-Lindau disease-associated vascular tumors in mice.
Volume: 25
Issue: 8
Pages: 3163-72
•
•
•
•
•
Publication
16129783 | J:100984
First Author: Mekhail K
Year: 2005
Journal: J Cell Biol
Title: Regulation of ubiquitin ligase dynamics by the nucleolus.
Volume: 170
Issue: 5
Pages: 733-44
•
•
•
•
•
Publication
27997827 | J:237617
First Author: Menendez-Montes I
Year: 2016
Journal: Dev Cell
Title: Myocardial VHL-HIF Signaling Controls an Embryonic Metabolic Switch Essential for Cardiac Maturation.
Volume: 39
Issue: 6
Pages: 724-739
•
•
•
•
•
Publication
27126173 | J:241555
First Author: Guinot A
Year: 2016
Journal: J Pathol
Title: Combined deletion of Vhl, Trp53 and Kif3a causes cystic and neoplastic renal lesions.
Volume: 239
Issue: 3
Pages: 365-73
•
•
•
•
•
Publication
29514656 | J:280346
First Author: Barben M
Year: 2018
Journal: Mol Neurodegener
Title: Targeting Hif1a rescues cone degeneration and prevents subretinal neovascularization in a model of chronic hypoxia.
Volume: 13
Issue: 1
Pages: 12
•
•
•
•
•
Publication
15601820 | J:94679
First Author: Kamura T
Year: 2004
Journal: Genes Dev
Title: VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases.
Volume: 18
Issue: 24
Pages: 3055-65
•
•
•
•
•
Publication
20388654 | J:160163
First Author: Kurihara T
Year: 2010
Journal: Development
Title: von Hippel-Lindau protein regulates transition from the fetal to the adult circulatory system in retina.
Volume: 137
Issue: 9
Pages: 1563-71
•
•
•
•
•
Publication
31142573 | J:276713
First Author: Cargill K
Year: 2019
Journal: J Am Soc Nephrol
Title: Von Hippel-Lindau Acts as a Metabolic Switch Controlling Nephron Progenitor Differentiation.
Volume: 30
Issue: 7
Pages: 1192-1205
•
•
•
•
•
Publication
25186293 | J:218695
First Author: Soggia A
Year: 2014
Journal: Diabetologia
Title: von Hippel-Lindau gene disruption in mouse pancreatic progenitors and its consequences on endocrine differentiation in vivo: importance of HIF1-α and VEGF-A upregulation.
Volume: 57
Issue: 11
Pages: 2348-56
•
•
•
•
•
Publication
28527294 | J:243840
First Author: Gerl K
Year: 2017
Journal: Am J Pathol
Title: Activation of Hypoxia Signaling in Stromal Progenitors Impairs Kidney Development.
Volume: 187
Issue: 7
Pages: 1496-1511
•
•
•
•
•
Publication
22627278 | J:185536
First Author: Lange CA
Year: 2012
Journal: Development
Title: Von Hippel-Lindau protein in the RPE is essential for normal ocular growth and vascular development.
Volume: 139
Issue: 13
Pages: 2340-50
•
•
•
•
•
Publication
32733884 | J:302030
 
First Author: Eberhart T
Year: 2020
Journal: Front Cell Dev Biol
Title: Peroxisome-Deficiency and HIF-2α Signaling Are Negative Regulators of Ketohexokinase Expression.
Volume: 8
Pages: 566
•
•
•
•
•
Publication
26488390 | J:250866
First Author: Zhou Q
Year: 2016
Journal: Am J Respir Cell Mol Biol
Title: Suppression of von Hippel-Lindau Protein in Fibroblasts Protects against Bleomycin-Induced Pulmonary Fibrosis.
Volume: 54
Issue: 5
Pages: 728-39
•
•
•
•
•
Publication
22977222 | J:193425
First Author: Neary MT
Year: 2013
Journal: Dis Model Mech
Title: A mouse model to study the link between hypoxia, long QT interval and sudden infant death syndrome.
Volume: 6
Issue: 2
Pages: 503-7
•
•
•
•
•
Publication
35118061 | J:326679
 
First Author: Chen K
Year: 2021
Journal: Front Cell Dev Biol
Title: Osteocytic HIF-1α Pathway Manipulates Bone Micro-structure and Remodeling via Regulating Osteocyte Terminal Differentiation.
Volume: 9
Pages: 721561
•
•
•
•
•
Publication
19808020 | J:153662
First Author: Chan SY
Year: 2009
Journal: Cell Metab
Title: MicroRNA-210 controls mitochondrial metabolism during hypoxia by repressing the iron-sulfur cluster assembly proteins ISCU1/2.
Volume: 10
Issue: 4
Pages: 273-84
•
•
•
•
•
Publication
18199804 | J:150172
First Author: Thorner PS
Year: 2008
Journal: J Am Soc Nephrol
Title: Podocytes contribute to the formation of glomerular crescents.
Volume: 19
Issue: 3
Pages: 495-502
•
•
•
•
•
Publication
35666812 | J:326991
First Author: Nguyen TN
Year: 2022
Journal: Cancer Res
Title: IL6 and CCL18 Mediate Cross-talk between VHL-Deficient Kidney Cells and Macrophages during Development of Renal Cell Carcinoma.
Volume: 82
Issue: 15
Pages: 2716-2733
•
•
•
•
•
Publication
25825391 | J:229258
First Author: White K
Year: 2015
Journal: EMBO Mol Med
Title: Genetic and hypoxic alterations of the microRNA-210-ISCU1/2 axis promote iron-sulfur deficiency and pulmonary hypertension.
Volume: 7
Issue: 6
Pages: 695-713
•
•
•
•
•
Publication
27422990 | J:236548
First Author: Slingo M
Year: 2016
Journal: Am J Physiol Heart Circ Physiol
Title: The von Hippel-Lindau Chuvash mutation in mice alters cardiac substrate and high-energy phosphate metabolism.
Volume: 311
Issue: 3
Pages: H759-67
•
•
•
•
•
Publication
8603073 | J:32429
First Author: Gnarra JR
Year: 1996
Journal: Biochim Biophys Acta
Title: Molecular cloning of the von Hippel-Lindau tumor suppressor gene and its role in renal carcinoma.
Volume: 1242
Issue: 3
Pages: 201-10
•
•
•
•
•
Publication
10353237 | J:55034
First Author: Kaelin WG Jr
Year: 1999
Journal: Nature
Title: Cancer. Many vessels, faulty gene.
Volume: 399
Issue: 6733
Pages: 203-4
•
•
•
•
•
Publication
21652636 | J:183052
First Author: Sinha S
Year: 2011
Journal: J Cell Sci
Title: Von Hippel-Lindau gene product directs cytokinesis: a new tumor suppressor function.
Volume: 124
Issue: Pt 13
Pages: 2132-42
•
•
•
•
•
Publication
18096761 | J:132718
First Author: Minamishima YA
Year: 2008
Journal: Blood
Title: Somatic inactivation of the PHD2 prolyl hydroxylase causes polycythemia and congestive heart failure.
Volume: 111
Issue: 6
Pages: 3236-44
•
•
•
•
•
Publication
27068470 | J:235179
First Author: Hamanaka RB
Year: 2016
Journal: Cell Rep
Title: The Mitochondrial Respiratory Chain Is Required for Organismal Adaptation to Hypoxia.
Volume: 15
Issue: 3
Pages: 451-459
•
•
•
•
•
Publication
33512384 | J:327650
First Author: Ghosh MC
Year: 2021
Journal: Blood
Title: Therapeutic inhibition of HIF-2α reverses polycythemia and pulmonary hypertension in murine models of human diseases.
Volume: 137
Issue: 18
Pages: 2509-2519
•
•
•
•
•
Publication
19720742 | J:153985
First Author: Minamishima YA
Year: 2009
Journal: Mol Cell Biol
Title: A feedback loop involving the Phd3 prolyl hydroxylase tunes the mammalian hypoxic response in vivo.
Volume: 29
Issue: 21
Pages: 5729-41
•
•
•
•
•
Publication
19147412 | J:145975
First Author: Shah YM
Year: 2009
Journal: Cell Metab
Title: Intestinal hypoxia-inducible transcription factors are essential for iron absorption following iron deficiency.
Volume: 9
Issue: 2
Pages: 152-64
•
•
•
•
•
Publication
38941187 | J:357395
First Author: Fan Z
Year: 2024
Journal: Cell Rep
Title: Macrophages preserve endothelial cell specialization in the adrenal gland to modulate aldosterone secretion and blood pressure.
Volume: 43
Issue: 7
Pages: 114395
•
•
•
•
•
Publication
35189575 | J:322643
 
First Author: Kotagiri P
Year: 2022
Journal: EBioMedicine
Title: The impact of hypoxia on B cells in COVID-19.
Volume: 77
Pages: 103878
•
•
•
•
•
Publication
29684361 | J:263758
First Author: Kuwahara Y
Year: 2018
Journal: Am J Pathol
Title: High Frequency of Ovarian Cyst Development in Vhl2B/+;Snf5+/- Mice.
Volume: 188
Issue: 7
Pages: 1510-1516
•
•
•
•
•
Publication
16007254 | J:99628
First Author: Peyssonnaux C
Year: 2005
Journal: J Clin Invest
Title: HIF-1alpha expression regulates the bactericidal capacity of phagocytes.
Volume: 115
Issue: 7
Pages: 1806-15
•
•
•
•
•
Publication
31518902 | J:347367
 
First Author: Nishide S
Year: 2019
Journal: iScience
Title: Controlling the Phenotype of Tumor-Infiltrating Macrophages via the PHD-HIF Axis Inhibits Tumor Growth in a Mouse Model.
Volume: 19
Pages: 940-954
•
•
•
•
•
Publication
26213713 | J:229425
 
First Author: Le Moan N
Year: 2015
Journal: eNeuro
Title: Hypoxia Inducible Factor-1α in Astrocytes and/or Myeloid Cells Is Not Required for the Development of Autoimmune Demyelinating Disease,.
Volume: 2
Issue: 2
•
•
•
•
•
Publication
36987917 | J:336567
First Author: Pelletier A
Year: 2023
Journal: EMBO Rep
Title: Resting natural killer cell homeostasis relies on tryptophan/NAD(+) metabolism and HIF-1α.
Volume: 24
Issue: 6
Pages: e56156
•
•
•
•
•
Publication
19056893 | J:142036
First Author: Zehetner J
Year: 2008
Journal: Genes Dev
Title: PVHL is a regulator of glucose metabolism and insulin secretion in pancreatic beta cells.
Volume: 22
Issue: 22
Pages: 3135-46
•
•
•
•
•
Publication
16286658 | J:103837
First Author: Neumann AK
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Hypoxia inducible factor 1 alpha regulates T cell receptor signal transduction.
Volume: 102
Issue: 47
Pages: 17071-6
•
•
•
•
•
Publication
25063991 | J:230108
First Author: Ong SG
Year: 2014
Journal: Cardiovasc Res
Title: HIF-1 reduces ischaemia-reperfusion injury in the heart by targeting the mitochondrial permeability transition pore.
Volume: 104
Issue: 1
Pages: 24-36
•
•
•
•
•
Publication
18184809 | J:131088
First Author: Wan C
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Activation of the hypoxia-inducible factor-1alpha pathway accelerates bone regeneration.
Volume: 105
Issue: 2
Pages: 686-91
•
•
•
•
•
Publication
15489957 | J:93476
First Author: Karhausen J
Year: 2004
Journal: J Clin Invest
Title: Epithelial hypoxia-inducible factor-1 is protective in murine experimental colitis.
Volume: 114
Issue: 8
Pages: 1098-106
•
•
•
•
•
Publication
35024767 | J:319520
 
First Author: Krzywinska E
Year: 2022
Journal: J Exp Med
Title: The transcription factor HIF-1α mediates plasticity of NKp46+ innate lymphoid cells in the gut.
Volume: 219
Issue: 2
•
•
•
•
•
Publication
16906157 | J:115017
First Author: Ding M
Year: 2006
Journal: Nat Med
Title: Loss of the tumor suppressor Vhlh leads to upregulation of Cxcr4 and rapidly progressive glomerulonephritis in mice.
Volume: 12
Issue: 9
Pages: 1081-7
•
•
•
•
•
Publication
24298056 | J:205272
First Author: Puri S
Year: 2013
Journal: Genes Dev
Title: VHL-mediated disruption of Sox9 activity compromises β-cell identity and results in diabetes mellitus.
Volume: 27
Issue: 23
Pages: 2563-75
•
•
•
•
•
Publication
17557118 | J:124039
First Author: Peyssonnaux C
Year: 2007
Journal: J Clin Invest
Title: Regulation of iron homeostasis by the hypoxia-inducible transcription factors (HIFs).
Volume: 117
Issue: 7
Pages: 1926-32
•
•
•
•
•
Publication
24646994 | J:208889
First Author: Kusumbe AP
Year: 2014
Journal: Nature
Title: Coupling of angiogenesis and osteogenesis by a specific vessel subtype in bone.
Volume: 507
Issue: 7492
Pages: 323-328
•
•
•
•
•
Publication
20733101 | J:179490
First Author: Moslehi J
Year: 2010
Journal: Circulation
Title: Loss of hypoxia-inducible factor prolyl hydroxylase activity in cardiomyocytes phenocopies ischemic cardiomyopathy.
Volume: 122
Issue: 10
Pages: 1004-16
•
•
•
•
•
Publication
22371328 | J:198097
First Author: Parikh VN
Year: 2012
Journal: Circulation
Title: MicroRNA-21 integrates pathogenic signaling to control pulmonary hypertension: results of a network bioinformatics approach.
Volume: 125
Issue: 12
Pages: 1520-32
•
•
•
•
•
Publication
17992257 | J:130780
First Author: Hickey MM
Year: 2007
Journal: J Clin Invest
Title: von Hippel-Lindau mutation in mice recapitulates Chuvash polycythemia via hypoxia-inducible factor-2alpha signaling and splenic erythropoiesis.
Volume: 117
Issue: 12
Pages: 3879-89
•
•
•
•
•
Publication
29480820 | J:261174
First Author: Ghosh MC
Year: 2018
Journal: J Clin Invest
Title: Translational repression of HIF2α expression in mice with Chuvash polycythemia reverses polycythemia.
Volume: 128
Issue: 4
Pages: 1317-1325
•
•
•
•
•
Publication
26215701 | J:238613
First Author: Zhang CS
Year: 2015
Journal: Cell Res
Title: RHOBTB3 promotes proteasomal degradation of HIFα through facilitating hydroxylation and suppresses the Warburg effect.
Volume: 25
Issue: 9
Pages: 1025-42
•
•
•
•
•
Publication
19419968 | J:151178
First Author: Tan SH
Year: 2009
Journal: J Biol Chem
Title: Regulation of cell proliferation and migration by TAK1 via transcriptional control of von Hippel-Lindau tumor suppressor.
Volume: 284
Issue: 27
Pages: 18047-58
•
•
•
•
•
Publication
25023702 | J:221254
First Author: Gómez-Maldonado L
Year: 2015
Journal: Oncogene
Title: EFNA3 long noncoding RNAs induced by hypoxia promote metastatic dissemination.
Volume: 34
Issue: 20
Pages: 2609-20
•
•
•
•
•
Publication
29279301 | J:319826
First Author: Fu C
Year: 2018
Journal: Circ Res
Title: Inositol Polyphosphate Multikinase Inhibits Angiogenesis via Inositol Pentakisphosphate-Induced HIF-1α Degradation.
Volume: 122
Issue: 3
Pages: 457-472
•
•
•
•
•
Publication
15082713 | J:91272
First Author: Hardy MP
Year: 2004
Journal: J Biol Chem
Title: The murine IRAK2 gene encodes four alternatively spliced isoforms, two of which are inhibitory.
Volume: 279
Issue: 26
Pages: 27699-708
•
•
•
•
•
Publication
23042097 | J:193648
First Author: Xue X
Year: 2013
Journal: Carcinogenesis
Title: Hypoxia-inducible factor-2α is essential in activating the COX2/mPGES-1/PGE2 signaling axis in colon cancer.
Volume: 34
Issue: 1
Pages: 163-9
•
•
•
•
•
Publication
34301760 | J:310829
First Author: Nguyen-Tran HH
Year: 2021
Journal: Cancer Res
Title: Endothelial Reprogramming Stimulated by Oncostatin M Promotes Inflammation and Tumorigenesis in VHL-Deficient Kidney Tissue.
Volume: 81
Issue: 19
Pages: 5060-5073
•
•
•
•
•
Publication
12832481 | J:84384
First Author: Park SK
Year: 2003
Journal: Mol Cell Biol
Title: Hypoxia-induced gene expression occurs solely through the action of hypoxia-inducible factor 1alpha (HIF-1alpha): role of cytoplasmic trapping of HIF-2alpha.
Volume: 23
Issue: 14
Pages: 4959-71
•
•
•
•
•
Publication
36413415 | J:333108
 
First Author: Seidel P
Year: 2022
Journal: JCI Insight
Title: ATR represents a therapeutic vulnerability in clear cell renal cell carcinoma.
Volume: 7
Issue: 24
•
•
•
•
•
Publication
28553932 | J:251276
First Author: Harlander S
Year: 2017
Journal: Nat Med
Title: Combined mutation in Vhl, Trp53 and Rb1 causes clear cell renal cell carcinoma in mice.
Volume: 23
Issue: 7
Pages: 869-877
•
•
•
•
•
Publication
24497508 | J:206831
First Author: Ahn GO
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Transcriptional activation of hypoxia-inducible factor-1 (HIF-1) in myeloid cells promotes angiogenesis through VEGF and S100A8.
Volume: 111
Issue: 7
Pages: 2698-703
•
•
•
•
•
Publication
20194441 | J:263290
First Author: Takeda N
Year: 2010
Journal: Genes Dev
Title: Differential activation and antagonistic function of HIF-{alpha} isoforms in macrophages are essential for NO homeostasis.
Volume: 24
Issue: 5
Pages: 491-501
•
•
•
•
•
Publication
29967068 | J:263648
 
First Author: Kim YE
Year: 2018
Journal: Dis Model Mech
Title: HIF-1α activation in myeloid cells accelerates dextran sodium sulfate-induced colitis progression in mice.
Volume: 11
Issue: 7
•
•
•
•
•
Publication
24076634 | J:208201
First Author: Doedens AL
Year: 2013
Journal: Nat Immunol
Title: Hypoxia-inducible factors enhance the effector responses of CD8(+) T cells to persistent antigen.
Volume: 14
Issue: 11
Pages: 1173-82
•
•
•
•
•
Publication
28473526 | J:243121
First Author: Gu YF
Year: 2017
Journal: Cancer Discov
Title: Modeling Renal Cell Carcinoma in Mice: Bap1 and Pbrm1 Inactivation Drive Tumor Grade.
Volume: 7
Issue: 8
Pages: 900-917
•
•
•
•
•
Publication
29666476 | J:269311
First Author: Barben M
Year: 2018
Journal: Cell Death Differ
Title: Hif1a inactivation rescues photoreceptor degeneration induced by a chronic hypoxia-like stress.
Volume: 25
Issue: 12
Pages: 2071-2085
•
•
•
•
•
Publication
29339479 | J:257753
First Author: Devignes CS
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: HIF signaling in osteoblast-lineage cells promotes systemic breast cancer growth and metastasis in mice.
Volume: 115
Issue: 5
Pages: E992-E1001
•
•
•
•
•
Publication
37117599 | J:339502
First Author: March-Diaz R
Year: 2021
Journal: Nat Aging
Title: Hypoxia compromises the mitochondrial metabolism of Alzheimer's disease microglia via HIF1.
Volume: 1
Issue: 4
Pages: 385-399
•
•
•
•
•
Publication
23977255 | J:206428
First Author: Puri S
Year: 2013
Journal: PLoS One
Title: Elimination of von Hippel-Lindau function perturbs pancreas endocrine homeostasis in mice.
Volume: 8
Issue: 8
Pages: e72213
•
•
•
•
•
Publication
23290136 | J:194930
First Author: Takubo K
Year: 2013
Journal: Cell Stem Cell
Title: Regulation of glycolysis by Pdk functions as a metabolic checkpoint for cell cycle quiescence in hematopoietic stem cells.
Volume: 12
Issue: 1
Pages: 49-61
•
•
•
•
•
Publication
24326162 | J:315910
First Author: Lin Q
Year: 2013
Journal: J Am Heart Assoc
Title: Activation of hypoxia-inducible factor-2 in adipocytes results in pathological cardiac hypertrophy.
Volume: 2
Issue: 6
Pages: e000548
•
•
•
•
•
Publication
18490920 | J:140075
First Author: Rankin EB
Year: 2008
Journal: Oncogene
Title: Hypoxia-inducible factor-2 regulates vascular tumorigenesis in mice.
Volume: 27
Issue: 40
Pages: 5354-8
•
•
•
•
•
Publication
24101470 | J:201979
First Author: Cowburn AS
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: HIF isoforms in the skin differentially regulate systemic arterial pressure.
Volume: 110
Issue: 43
Pages: 17570-5
•
•
•
•
•
Publication
29035368 | J:252613
First Author: Xie C
Year: 2017
Journal: Nat Med
Title: Activation of intestinal hypoxia-inducible factor 2α during obesity contributes to hepatic steatosis.
Volume: 23
Issue: 11
Pages: 1298-1308
•
•
•
•
•
Publication
25018103 | J:214629
First Author: Yuen TJ
Year: 2014
Journal: Cell
Title: Oligodendrocyte-encoded HIF function couples postnatal myelination and white matter angiogenesis.
Volume: 158
Issue: 2
Pages: 383-396
•
•
•
•
•
Publication
27991597 | J:243450
 
First Author: Jablonska B
Year: 2016
Journal: Nat Commun
Title: Sirt1 regulates glial progenitor proliferation and regeneration in white matter after neonatal brain injury.
Volume: 7
Pages: 13866
•
•
•
•
•
Publication
19528226 | J:151523
First Author: Rankin EB
Year: 2009
Journal: Mol Cell Biol
Title: Hypoxia-inducible factor 2 regulates hepatic lipid metabolism.
Volume: 29
Issue: 16
Pages: 4527-38
•
•
•
•
•
Publication
35145086 | J:330302
First Author: Huang B
Year: 2022
Journal: Nat Commun
Title: In vivo CRISPR screens reveal a HIF-1α-mTOR-network regulates T follicular helper versus Th1 cells.
Volume: 13
Issue: 1
Pages: 805
•
•
•
•
•
Publication
29617647 | J:262003
First Author: Sim J
Year: 2018
Journal: Cell Metab
Title: The Factor Inhibiting HIF Asparaginyl Hydroxylase Regulates Oxidative Metabolism and Accelerates Metabolic Adaptation to Hypoxia.
Volume: 27
Issue: 4
Pages: 898-913.e7
•
•
•
•
•
Publication
25023703 | J:221253
First Author: Pritchett TL
Year: 2015
Journal: Oncogene
Title: Conditional inactivation of the mouse von Hippel-Lindau tumor suppressor gene results in wide-spread hyperplastic, inflammatory and fibrotic lesions in the kidney.
Volume: 34
Issue: 20
Pages: 2631-9
•
•
•
•
•
Publication
20628150 | J:165868
First Author: Kapitsinou PP
Year: 2010
Journal: Blood
Title: Hepatic HIF-2 regulates erythropoietic responses to hypoxia in renal anemia.
Volume: 116
Issue: 16
Pages: 3039-48
•
•
•
•
•
Publication
23860500 | J:265110
First Author: Xue X
Year: 2013
Journal: Gastroenterology
Title: Endothelial PAS domain protein 1 activates the inflammatory response in the intestinal epithelium to promote colitis in mice.
Volume: 145
Issue: 4
Pages: 831-41
•
•
•
•
•
Publication
27798602 | J:243079
First Author: Tyrakis PA
Year: 2016
Journal: Nature
Title: S-2-hydroxyglutarate regulates CD8+ T-lymphocyte fate.
Volume: 540
Issue: 7632
Pages: 236-241
•
•
•
•
•
Publication
22207131 | J:182569
First Author: Ikejiri A
Year: 2012
Journal: Int Immunol
Title: Dynamic regulation of Th17 differentiation by oxygen concentrations.
Volume: 24
Issue: 3
Pages: 137-46
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom