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Search results 1001 to 1100 out of 1419 for Pdx1

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Type Details Score
Publication
36828915 | J:335437
First Author: Low RRJ
Year: 2023
Journal: Cell Death Differ
Title: S100 family proteins are linked to organoid morphology and EMT in pancreatic cancer.
Volume: 30
Issue: 5
Pages: 1155-1165
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Publication
24041692 | J:211430
First Author: Lee JC
Year: 2013
Journal: Biochem Biophys Res Commun
Title: Trisomy of the Dscr1 gene suppresses early progression of pancreatic intraepithelial neoplasia driven by oncogenic Kras.
Volume: 440
Issue: 1
Pages: 50-5
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Publication
31699795 | J:284231
First Author: Dominguez CX
Year: 2020
Journal: Cancer Discov
Title: Single-Cell RNA Sequencing Reveals Stromal Evolution into LRRC15+ Myofibroblasts as a Determinant of Patient Response to Cancer Immunotherapy.
Volume: 10
Issue: 2
Pages: 232-253
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Publication
31662451 | J:284232
First Author: Dey S
Year: 2020
Journal: Mol Cancer Res
Title: miR-29a Is Repressed by MYC in Pancreatic Cancer and Its Restoration Drives Tumor-Suppressive Effects via Downregulation of LOXL2.
Volume: 18
Issue: 2
Pages: 311-323
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Publication
23076356 | J:189216
First Author: Chugh R
Year: 2012
Journal: Sci Transl Med
Title: A preclinical evaluation of Minnelide as a therapeutic agent against pancreatic cancer.
Volume: 4
Issue: 156
Pages: 156ra139
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Publication
37814340 | J:358043
First Author: Okabe J
Year: 2023
Journal: J Exp Clin Cancer Res
Title: Regnase-1 downregulation promotes pancreatic cancer through myeloid-derived suppressor cell-mediated evasion of anticancer immunity.
Volume: 42
Issue: 1
Pages: 262
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Publication
27659181 | J:237851
First Author: Leal AS
Year: 2016
Journal: Carcinogenesis
Title: The triterpenoid CDDO-imidazolide reduces immune cell infiltration and cytokine secretion in the KrasG12D;Pdx1-Cre (KC) mouse model of pancreatic cancer.
Volume: 37
Issue: 12
Pages: 1170-1179
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Publication
25250570 | J:217621
First Author: Garcia MN
Year: 2014
Journal: J Clin Invest
Title: IER3 supports KRASG12D-dependent pancreatic cancer development by sustaining ERK1/2 phosphorylation.
Volume: 124
Issue: 11
Pages: 4709-22
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Publication
34534538 | J:316410
First Author: Ganguly K
Year: 2022
Journal: Gastroenterology
Title: Mucin 5AC Serves as the Nexus for β-Catenin/c-Myc Interplay to Promote Glutamine Dependency During Pancreatic Cancer Chemoresistance.
Volume: 162
Issue: 1
Pages: 253-268.e13
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Publication
25261994 | J:227828
First Author: Mayers JR
Year: 2014
Journal: Nat Med
Title: Elevation of circulating branched-chain amino acids is an early event in human pancreatic adenocarcinoma development.
Volume: 20
Issue: 10
Pages: 1193-1198
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Publication
29237705 | J:257588
First Author: Deng YZ
Year: 2018
Journal: J Exp Med
Title: Cilia loss sensitizes cells to transformation by activating the mevalonate pathway.
Volume: 215
Issue: 1
Pages: 177-195
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Publication
26408346 | J:263517
First Author: Qiu W
Year: 2016
Journal: Gastroenterology
Title: Loss of Activin Receptor Type 1B Accelerates Development of Intraductal Papillary Mucinous Neoplasms in Mice With Activated KRAS.
Volume: 150
Issue: 1
Pages: 218-228.e12
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Publication
37445930 | J:337929
 
First Author: Cortez NE
Year: 2023
Journal: Int J Mol Sci
Title: A Ketogenic Diet in Combination with Gemcitabine Mitigates Pancreatic Cancer-Associated Cachexia in Male and Female KPC Mice.
Volume: 24
Issue: 13
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Publication
30498210 | J:267629
First Author: Novo D
Year: 2018
Journal: Nat Commun
Title: Mutant p53s generate pro-invasive niches by influencing exosome podocalyxin levels.
Volume: 9
Issue: 1
Pages: 5069
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Publication
34245764 | J:312409
First Author: Hu T
Year: 2021
Journal: Gastroenterology
Title: Metabolic Rewiring by Loss of Sirt5 Promotes Kras-Induced Pancreatic Cancer Progression.
Volume: 161
Issue: 5
Pages: 1584-1600
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Publication
26617245 | J:251590
 
First Author: Grasso D
Year: 2015
Journal: Sci Rep
Title: Pivotal Role of the Chromatin Protein Nupr1 in Kras-Induced Senescence and Transformation.
Volume: 5
Pages: 17549
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Publication
35307861 | J:332833
First Author: Gouirand V
Year: 2022
Journal: EMBO J
Title: Ketogenic HMG-CoA lyase and its product β-hydroxybutyrate promote pancreatic cancer progression.
Volume: 41
Issue: 9
Pages: e110466
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Publication
28685754 | J:249571
 
First Author: Olivares O
Year: 2017
Journal: Nat Commun
Title: Collagen-derived proline promotes pancreatic ductal adenocarcinoma cell survival under nutrient limited conditions.
Volume: 8
Pages: 16031
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Publication
26216548 | J:225891
First Author: Li T
Year: 2015
Journal: Cancer Res
Title: Pulsed High-Intensity Focused Ultrasound Enhances Delivery of Doxorubicin in a Preclinical Model of Pancreatic Cancer.
Volume: 75
Issue: 18
Pages: 3738-46
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Publication
27742686 | J:238015
First Author: Ireland L
Year: 2016
Journal: Cancer Res
Title: Chemoresistance in Pancreatic Cancer Is Driven by Stroma-Derived Insulin-Like Growth Factors.
Volume: 76
Issue: 23
Pages: 6851-6863
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Publication
28394331 | J:251630
First Author: Daley D
Year: 2017
Journal: Nat Med
Title: Dectin 1 activation on macrophages by galectin 9 promotes pancreatic carcinoma and peritumoral immune tolerance.
Volume: 23
Issue: 5
Pages: 556-567
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Publication
23494546 | J:204869
First Author: Mastracci TL
Year: 2013
Journal: Transgenic Res
Title: Generation of mice encoding a conditional allele of Nkx2.2.
Volume: 22
Issue: 5
Pages: 965-72
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Publication
29532564 | J:263063
First Author: Das KK
Year: 2018
Journal: Dev Dyn
Title: ETV5 regulates ductal morphogenesis with Sox9 and is critical for regeneration from pancreatitis.
Volume: 247
Issue: 6
Pages: 854-866
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Publication
29559448 | J:260455
 
First Author: Yu XX
Year: 2018
Journal: Development
Title: Dynamics of chromatin marks and the role of JMJD3 during pancreatic endocrine cell fate commitment.
Volume: 145
Issue: 6
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Publication
25107471 | J:216065
First Author: Xu CR
Year: 2014
Journal: EMBO J
Title: Dynamics of genomic H3K27me3 domains and role of EZH2 during pancreatic endocrine specification.
Volume: 33
Issue: 19
Pages: 2157-70
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Publication
19131512 | J:145696
First Author: Crawford LA
Year: 2009
Journal: Mol Endocrinol
Title: Connective tissue growth factor (CTGF) inactivation leads to defects in islet cell lineage allocation and beta-cell proliferation during embryogenesis.
Volume: 23
Issue: 3
Pages: 324-36
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Publication
26917725 | J:233713
First Author: Kuo T
Year: 2016
Journal: J Biol Chem
Title: Altered Plasma Profile of Antioxidant Proteins as an Early Correlate of Pancreatic β Cell Dysfunction.
Volume: 291
Issue: 18
Pages: 9648-56
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Publication
27818940 | J:350193
First Author: Schulz N
Year: 2016
Journal: Mol Metab
Title: Critical role for adenosine receptor A2a in β-cell proliferation.
Volume: 5
Issue: 11
Pages: 1138-1146
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Publication
32616519 | J:302537
First Author: Marcheva B
Year: 2020
Journal: Genes Dev
Title: A role for alternative splicing in circadian control of exocytosis and glucose homeostasis.
Volume: 34
Issue: 15-16
Pages: 1089-1105
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Publication
29330353 | J:260459
First Author: Azizoglu DB
Year: 2017
Journal: Genes Dev
Title: Afadin and RhoA control pancreatic endocrine mass via lumen morphogenesis.
Volume: 31
Issue: 23-24
Pages: 2376-2390
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Publication
24520122 | J:229341
First Author: Hang Y
Year: 2014
Journal: Diabetes
Title: The MafA transcription factor becomes essential to islet β-cells soon after birth.
Volume: 63
Issue: 6
Pages: 1994-2005
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Publication
21085706 | J:166813
First Author: Gustavsson N
Year: 2010
Journal: PLoS One
Title: Neuronal calcium sensor synaptotagmin-9 is not involved in the regulation of glucose homeostasis or insulin secretion.
Volume: 5
Issue: 11
Pages: e15414
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Publication
32764399 | J:302369
 
First Author: Deng Z
Year: 2020
Journal: Int J Mol Sci
Title: An Inducible Diabetes Mellitus Murine Model Based on MafB Conditional Knockout under MafA-Deficient Condition.
Volume: 21
Issue: 16
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Publication
30209343 | J:278058
First Author: Flores-Martínez A
Year: 2018
Journal: Sci Rep
Title: Stabilization of HIF-2α impacts pancreas growth.
Volume: 8
Issue: 1
Pages: 13713
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Publication
31513344 | J:281756
First Author: Nunez L
Year: 2019
Journal: Genesis
Title: Generation of a novel mouse strain with conditional, cell-type specific, expression of DND1.
Volume: 57
Issue: 11-12
Pages: e23335
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Publication
26471901 | J:232368
First Author: Xiong X
Year: 2016
Journal: Diabetologia
Title: Sirtuin 6 regulates glucose-stimulated insulin secretion in mouse pancreatic beta cells.
Volume: 59
Issue: 1
Pages: 151-60
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Publication
28856392 | J:317886
First Author: Bengsch F
Year: 2017
Journal: Cancer Immunol Immunother
Title: CTLA-4/CD80 pathway regulates T cell infiltration into pancreatic cancer.
Volume: 66
Issue: 12
Pages: 1609-1617
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Publication
26389676 | J:226392
First Author: Ferdaoussi M
Year: 2015
Journal: J Clin Invest
Title: Isocitrate-to-SENP1 signaling amplifies insulin secretion and rescues dysfunctional β cells.
Volume: 125
Issue: 10
Pages: 3847-60
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Publication
23370328 | J:196877
First Author: Wauters E
Year: 2013
Journal: Cancer Res
Title: Sirtuin-1 regulates acinar-to-ductal metaplasia and supports cancer cell viability in pancreatic cancer.
Volume: 73
Issue: 7
Pages: 2357-67
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Publication
38184650 | J:346178
First Author: Lin H
Year: 2024
Journal: Nat Commun
Title: A role and mechanism for redox sensing by SENP1 in β-cell responses to high fat feeding.
Volume: 15
Issue: 1
Pages: 334
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Publication
30001807 | J:273419
First Author: Iwahashi K
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Autophagy impairment in pancreatic acinar cells causes zymogen granule accumulation and pancreatitis.
Volume: 503
Issue: 4
Pages: 2576-2582
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Publication
37198398 | J:337526
First Author: Araki O
Year: 2023
Journal: Oncogene
Title: Brg1 controls stemness and metastasis of pancreatic cancer through regulating hypoxia pathway.
Volume: 42
Issue: 26
Pages: 2139-2152
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Publication
29920275 | J:263870
First Author: Reichert M
Year: 2018
Journal: Dev Cell
Title: Regulation of Epithelial Plasticity Determines Metastatic Organotropism in Pancreatic Cancer.
Volume: 45
Issue: 6
Pages: 696-711.e8
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Publication
18421434 | J:137920
First Author: Mehrabian M
Year: 2008
Journal: Diabetologia
Title: Identification of ALOX5 as a gene regulating adiposity and pancreatic function.
Volume: 51
Issue: 6
Pages: 978-88
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Publication
26546129 | J:230840
First Author: Jurczyk A
Year: 2016
Journal: FASEB J
Title: Beyond the brain: disrupted in schizophrenia 1 regulates pancreatic β-cell function via glycogen synthase kinase-3β.
Volume: 30
Issue: 2
Pages: 983-93
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Publication
28642969 | J:252014
First Author: Ida S
Year: 2017
Journal: Diabetologia
Title: Diverse metabolic effects of O-GlcNAcylation in the pancreas but limited effects in insulin-sensitive organs in mice.
Volume: 60
Issue: 9
Pages: 1761-1769
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Publication
12493745 | J:82924
First Author: Terauchi Y
Year: 2003
Journal: J Biol Chem
Title: Impact of genetic background and ablation of insulin receptor substrate (IRS)-3 on IRS-2 knock-out mice.
Volume: 278
Issue: 16
Pages: 14284-90
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Publication
23531612 | J:198216
First Author: Crivello M
Year: 2013
Journal: Am J Physiol Endocrinol Metab
Title: Postnatal development of the endocrine pancreas in mice lacking functional GABAB receptors.
Volume: 304
Issue: 10
Pages: E1064-76
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Publication
22374815 | J:188469
First Author: Johnson CL
Year: 2012
Journal: J Pathol
Title: Activation of protein kinase Cδ leads to increased pancreatic acinar cell dedifferentiation in the absence of MIST1.
Volume: 228
Issue: 3
Pages: 351-65
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Publication
24989997 | J:218130
First Author: Chen YC
Year: 2014
Journal: Diabetologia
Title: Mig6 haploinsufficiency protects mice against streptozotocin-induced diabetes.
Volume: 57
Issue: 10
Pages: 2066-75
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Publication
23251699 | J:195661
First Author: van der Meulen T
Year: 2012
Journal: PLoS One
Title: Urocortin 3 marks mature human primary and embryonic stem cell-derived pancreatic alpha and beta cells.
Volume: 7
Issue: 12
Pages: e52181
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Publication
28377501 | J:243672
First Author: Mitchell RK
Year: 2017
Journal: J Biol Chem
Title: The transcription factor Pax6 is required for pancreatic β cell identity, glucose-regulated ATP synthesis, and Ca2+ dynamics in adult mice.
Volume: 292
Issue: 21
Pages: 8892-8906
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Publication
22230751 | J:182707
First Author: Miki R
Year: 2012
Journal: Mech Dev
Title: Fate maps of ventral and dorsal pancreatic progenitor cells in early somite stage mouse embryos.
Volume: 128
Issue: 11-12
Pages: 597-609
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Publication
1825611 | -
First Author: Russell GC
Year: 1991
Journal: Biochim Biophys Acta
Title: Sequence similarities within the family of dihydrolipoamide acyltransferases and discovery of a previously unidentified fungal enzyme.
Volume: 1076
Issue: 2
Pages: 225-32
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Publication
20865670 | -
First Author: Kang HS
Year: 2010
Journal: Histol Histopathol
Title: Gli-similar (Glis) Krüppel-like zinc finger proteins: insights into their physiological functions and critical roles in neonatal diabetes and cystic renal disease.
Volume: 25
Issue: 11
Pages: 1481-96
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Publication
21996748 | J:186130
First Author: Whipple CA
Year: 2012
Journal: Oncogene
Title: A KrasG12D-driven genetic mouse model of pancreatic cancer requires glypican-1 for efficient proliferation and angiogenesis.
Volume: 31
Issue: 20
Pages: 2535-44
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Publication
22565310 | J:188293
First Author: Hamidi T
Year: 2012
Journal: J Clin Invest
Title: Nuclear protein 1 promotes pancreatic cancer development and protects cells from stress by inhibiting apoptosis.
Volume: 122
Issue: 6
Pages: 2092-103
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24949970 | J:214528
First Author: Soleimanpour SA
Year: 2014
Journal: Cell
Title: The diabetes susceptibility gene Clec16a regulates mitophagy.
Volume: 157
Issue: 7
Pages: 1577-90
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Publication
21051638 | J:218666
First Author: Kraman M
Year: 2010
Journal: Science
Title: Suppression of antitumor immunity by stromal cells expressing fibroblast activation protein-alpha.
Volume: 330
Issue: 6005
Pages: 827-30
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Publication
20627934 | J:169626
First Author: Artner I
Year: 2010
Journal: Diabetes
Title: MafA and MafB regulate genes critical to beta-cells in a unique temporal manner.
Volume: 59
Issue: 10
Pages: 2530-9
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Publication
32179091 | J:348824
First Author: Ma Y
Year: 2020
Journal: Gastroenterology
Title: Combination of PD-1 Inhibitor and OX40 Agonist Induces Tumor Rejection and Immune Memory in Mouse Models of Pancreatic Cancer.
Volume: 159
Issue: 1
Pages: 306-319.e12
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Publication
21059956 | J:166586
First Author: Yang Y
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Reversal of preexisting hyperglycemia in diabetic mice by acute deletion of the Men1 gene.
Volume: 107
Issue: 47
Pages: 20358-63
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Publication
29914854 | J:315908
 
First Author: Burke SJ
Year: 2018
Journal: Mol Metab
Title: Pancreatic deletion of the interleukin-1 receptor disrupts whole body glucose homeostasis and promotes islet β-cell de-differentiation.
Volume: 14
Pages: 95-107
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Publication
35479410 | J:332306
First Author: Nayak D
Year: 2022
Journal: iScience
Title: EMT alterations in the solute carrier landscape uncover SLC22A10/A15 imposed vulnerabilities in pancreatic cancer.
Volume: 25
Issue: 5
Pages: 104193
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Publication
30366930 | J:271300
First Author: Biffi G
Year: 2019
Journal: Cancer Discov
Title: IL1-Induced JAK/STAT Signaling Is Antagonized by TGFβ to Shape CAF Heterogeneity in Pancreatic Ductal Adenocarcinoma.
Volume: 9
Issue: 2
Pages: 282-301
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Publication
37641131 | J:348898
First Author: Bastos N
Year: 2023
Journal: J Transl Med
Title: SMC3 epigenetic silencing regulates Rab27a expression and drives pancreatic cancer progression.
Volume: 21
Issue: 1
Pages: 578
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Publication
26479921 | J:228885
First Author: Alam MS
Year: 2015
Journal: Nat Med
Title: Selective inhibition of the p38 alternative activation pathway in infiltrating T cells inhibits pancreatic cancer progression.
Volume: 21
Issue: 11
Pages: 1337-43
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Publication
36384095 | J:348556
First Author: Frank KJ
Year: 2022
Journal: Cell Rep Med
Title: Extensive preclinical validation of combined RMC-4550 and LY3214996 supports clinical investigation for KRAS mutant pancreatic cancer.
Volume: 3
Issue: 11
Pages: 100815
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Publication
23873029 | J:212617
First Author: Tan EH
Year: 2014
Journal: Oncogene
Title: Functions of TAp63 and p53 in restraining the development of metastatic cancer.
Volume: 33
Issue: 25
Pages: 3325-33
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Publication
33323382 | J:303990
First Author: Kon N
Year: 2021
Journal: Cancer Res
Title: Robust p53 Stabilization Is Dispensable for Its Activation and Tumor Suppressor Function.
Volume: 81
Issue: 4
Pages: 935-944
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Publication
34188043 | J:307917
First Author: Isermann T
Year: 2021
Journal: Nat Commun
Title: Suppression of HSF1 activity by wildtype p53 creates a driving force for p53 loss-of-heterozygosity.
Volume: 12
Issue: 1
Pages: 4019
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Publication
34388391 | J:316758
First Author: Koikawa K
Year: 2021
Journal: Cell
Title: Targeting Pin1 renders pancreatic cancer eradicable by synergizing with immunochemotherapy.
Volume: 184
Issue: 18
Pages: 4753-4771.e27
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Publication
31911451 | J:285832
First Author: Zhang Y
Year: 2020
Journal: Cancer Discov
Title: Regulatory T-cell Depletion Alters the Tumor Microenvironment and Accelerates Pancreatic Carcinogenesis.
Volume: 10
Issue: 3
Pages: 422-439
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Publication
38935717 | J:352250
First Author: Mahadevan KK
Year: 2024
Journal: Science
Title: Type I conventional dendritic cells facilitate immunotherapy in pancreatic cancer.
Volume: 384
Issue: 6703
Pages: eadh4567
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Publication
31183403 | J:288756
First Author: Hari P
Year: 2019
Journal: Sci Adv
Title: The innate immune sensor Toll-like receptor 2 controls the senescence-associated secretory phenotype.
Volume: 5
Issue: 6
Pages: eaaw0254
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Publication
22738914 | J:191028
First Author: Lampson BL
Year: 2012
Journal: Cancer Res
Title: Targeting eNOS in pancreatic cancer.
Volume: 72
Issue: 17
Pages: 4472-82
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Publication
28808255 | J:250841
First Author: Zaytouni T
Year: 2017
Journal: Nat Commun
Title: Critical role for arginase 2 in obesity-associated pancreatic cancer.
Volume: 8
Issue: 1
Pages: 242
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Publication
18515092 | J:141804
First Author: Fendrich V
Year: 2008
Journal: Gastroenterology
Title: Hedgehog signaling is required for effective regeneration of exocrine pancreas.
Volume: 135
Issue: 2
Pages: 621-31
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Publication
29533787 | J:258620
First Author: Andricovich J
Year: 2018
Journal: Cancer Cell
Title: Loss of KDM6A Activates Super-Enhancers to Induce Gender-Specific Squamous-like Pancreatic Cancer and Confers Sensitivity to BET Inhibitors.
Volume: 33
Issue: 3
Pages: 512-526.e8
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Publication
17114584 | J:116130
First Author: Bardeesy N
Year: 2006
Journal: Genes Dev
Title: Smad4 is dispensable for normal pancreas development yet critical in progression and tumor biology of pancreas cancer.
Volume: 20
Issue: 22
Pages: 3130-46
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Publication
28294115 | J:244261
 
First Author: Gundry C
Year: 2017
Journal: Nat Commun
Title: Phosphorylation of Rab-coupling protein by LMTK3 controls Rab14-dependent EphA2 trafficking to promote cell:cell repulsion.
Volume: 8
Pages: 14646
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Publication
22113502 | J:198619
First Author: Qiu W
Year: 2011
Journal: Oncotarget
Title: Disruption of p16 and activation of Kras in pancreas increase ductal adenocarcinoma formation and metastasis in vivo.
Volume: 2
Issue: 11
Pages: 862-73
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Publication
16585505 | J:108298
First Author: Bardeesy N
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Both p16(Ink4a) and the p19(Arf)-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse.
Volume: 103
Issue: 15
Pages: 5947-52
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Publication
20807812 | J:164210
First Author: Hill R
Year: 2010
Journal: Cancer Res
Title: PTEN loss accelerates KrasG12D-induced pancreatic cancer development.
Volume: 70
Issue: 18
Pages: 7114-24
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Publication
22611036 | J:187012
First Author: Singh M
Year: 2012
Journal: J Pathol
Title: Anti-VEGF antibody therapy does not promote metastasis in genetically engineered mouse tumour models.
Volume: 227
Issue: 4
Pages: 417-30
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