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Search results 1001 to 1100 out of 2663 for Psen1

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Category: Publication
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Type Details Score
Publication
20854432 | J:166955
First Author: Zhang D
Year: 2010
Journal: J Neurochem
Title: Inactivation of presenilins causes pre-synaptic impairment prior to post-synaptic dysfunction.
Volume: 115
Issue: 5
Pages: 1215-21
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Publication
36710361 | J:344570
First Author: Lee SH
Year: 2023
Journal: Mol Brain
Title: Presenilins regulate synaptic plasticity in the perforant pathways of the hippocampus.
Volume: 16
Issue: 1
Pages: 17
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Publication
18353561 | J:136064
First Author: Sompol P
Year: 2008
Journal: Neuroscience
Title: A neuronal model of Alzheimer's disease: an insight into the mechanisms of oxidative stress-mediated mitochondrial injury.
Volume: 153
Issue: 1
Pages: 120-30
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Publication
21257234 | J:188220
First Author: Malthankar-Phatak G
Year: 2012
Journal: Neurobiol Aging
Title: Combination therapy prevents amyloid-dependent and -independent structural changes.
Volume: 33
Issue: 7
Pages: 1273-83
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Publication
21798347 | J:178563
First Author: Bruce-Keller AJ
Year: 2011
Journal: Neurobiol Dis
Title: Cognitive impairment in humanized APP×PS1 mice is linked to Aβ(1-42) and NOX activation.
Volume: 44
Issue: 3
Pages: 317-26
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Publication
17912741 | J:132038
First Author: Aoki C
Year: 2007
Journal: J Comp Neurol
Title: Chemical and morphological alterations of spines within the hippocampus and entorhinal cortex precede the onset of Alzheimer's disease pathology in double knock-in mice.
Volume: 505
Issue: 4
Pages: 352-62
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Publication
16325786 | J:103913
First Author: Mahadomrongkul V
Year: 2005
Journal: Brain Res
Title: Stability of the distribution of spines containing drebrin A in the sensory cortex layer I of mice expressing mutated APP and PS1 genes.
Volume: 1064
Issue: 1-2
Pages: 66-74
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Publication
18762245 | J:141188
First Author: Abdul HM
Year: 2008
Journal: Free Radic Biol Med
Title: Oxidative damage in brain from human mutant APP/PS-1 double knock-in mice as a function of age.
Volume: 45
Issue: 10
Pages: 1420-5
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Publication
17070803 | J:141506
First Author: Zhang C
Year: 2007
Journal: Exp Neurol
Title: Long-lasting impairment in hippocampal neurogenesis associated with amyloid deposition in a knock-in mouse model of familial Alzheimer's disease.
Volume: 204
Issue: 1
Pages: 77-87
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Publication
16478525 | J:106153
First Author: Mohmmad Abdul H
Year: 2006
Journal: J Neurochem
Title: Mutations in amyloid precursor protein and presenilin-1 genes increase the basal oxidative stress in murine neuronal cells and lead to increased sensitivity to oxidative stress mediated by amyloid beta-peptide (1-42), HO and kainic acid: implications for Alzheimer's disease.
Volume: 96
Issue: 5
Pages: 1322-35
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Publication
22634208 | J:187073
First Author: Duncan MJ
Year: 2012
Journal: Exp Neurol
Title: Effects of aging and genotype on circadian rhythms, sleep, and clock gene expression in APPxPS1 knock-in mice, a model for Alzheimer's disease.
Volume: 236
Issue: 2
Pages: 249-58
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Publication
22265986 | J:182539
First Author: Thibault O
Year: 2012
Journal: Biochim Biophys Acta
Title: Reduction in neuronal L-type calcium channel activity in a double knock-in mouse model of Alzheimer's disease.
Volume: 1822
Issue: 4
Pages: 546-9
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Publication
19303433 | J:150380
First Author: Lovell MA
Year: 2009
Journal: Free Radic Biol Med
Title: Organoselenium (Sel-Plex diet) decreases amyloid burden and RNA and DNA oxidative damage in APP/PS1 mice.
Volume: 46
Issue: 11
Pages: 1527-33
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Publication
19046405 | J:310291
First Author: Studzinski CM
Year: 2009
Journal: J Neurochem
Title: Effects of short-term Western diet on cerebral oxidative stress and diabetes related factors in APP x PS1 knock-in mice.
Volume: 108
Issue: 4
Pages: 860-6
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Publication
23415649 | J:209342
 
First Author: Beckett TL
Year: 2013
Journal: Brain Res
Title: A ketogenic diet improves motor performance but does not affect β-amyloid levels in a mouse model of Alzheimer's disease.
Volume: 1505
Pages: 61-7
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Publication
17651976 | J:124669
First Author: Murphy MP
Year: 2007
Journal: Neurobiol Dis
Title: Abeta solubility and deposition during AD progression and in APPxPS-1 knock-in mice.
Volume: 27
Issue: 3
Pages: 301-11
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Publication
30529693 | J:271598
 
First Author: Macheda T
Year: 2019
Journal: Neuroscience
Title: Chronic Intermittent Hypoxia Induces Robust Astrogliosis in an Alzheimer's Disease-Relevant Mouse Model.
Volume: 398
Pages: 55-63
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Publication
16651627 | J:108575
First Author: Anantharaman M
Year: 2006
Journal: Am J Pathol
Title: Beta-amyloid mediated nitration of manganese superoxide dismutase: implication for oxidative stress in a APPNLH/NLH X PS-1P264L/P264L double knock-in mouse model of Alzheimer's disease.
Volume: 168
Issue: 5
Pages: 1608-18
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Publication
32943069 | J:351269
First Author: Braun DJ
Year: 2020
Journal: J Neuroinflammation
Title: Microglial-associated responses to comorbid amyloid pathology and hyperhomocysteinemia in an aged knock-in mouse model of Alzheimer's disease.
Volume: 17
Issue: 1
Pages: 274
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Publication
20083199 | J:159931
First Author: Bader Lange ML
Year: 2010
Journal: Neurobiol Dis
Title: Age-related loss of phospholipid asymmetry in APP(NLh)/APP(NLh) x PS-1(P264L)/PS-1(P264L) human double mutant knock-in mice: relevance to Alzheimer disease.
Volume: 38
Issue: 1
Pages: 104-15
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Publication
16492745 | J:107171
First Author: Chang EH
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: AMPA receptor downscaling at the onset of Alzheimer's disease pathology in double knockin mice.
Volume: 103
Issue: 9
Pages: 3410-5
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Publication
15254914 | J:91716
First Author: Nakajima M
Year: 2004
Journal: Dev Dyn
Title: Presenilin 1 is essential for cardiac morphogenesis.
Volume: 230
Issue: 4
Pages: 795-9
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Publication
19889624 | J:159128
First Author: Couturier J
Year: 2010
Journal: J Biol Chem
Title: Interaction of double-stranded RNA-dependent protein kinase (PKR) with the death receptor signaling pathway in amyloid beta (Abeta)-treated cells and in APPSLPS1 knock-in mice.
Volume: 285
Issue: 2
Pages: 1272-82
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Publication
15953364 | J:99422
First Author: Lafay-Chebassier C
Year: 2005
Journal: J Neurochem
Title: mTOR/p70S6k signalling alteration by Abeta exposure as well as in APP-PS1 transgenic models and in patients with Alzheimer's disease.
Volume: 94
Issue: 1
Pages: 215-25
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Publication
29107091 | J:257191
First Author: Zheng H
Year: 2018
Journal: Biochim Biophys Acta
Title: The hypothalamus as the primary brain region of metabolic abnormalities in APP/PS1 transgenic mouse model of Alzheimer's disease.
Volume: 1864
Issue: 1
Pages: 263-273
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Publication
24293237 | J:351727
First Author: Cao Z
Year: 2014
Journal: Proteomics
Title: Proteome characterization of splenocytes from an Aβpp/ps-1 Alzheimer's disease model.
Volume: 14
Issue: 2-3
Pages: 291-7
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Publication
38143343 | J:359066
First Author: Britz J
Year: 2024
Journal: J Alzheimers Dis
Title: Sex-Dependent Effects of Chronic Circadian Disruption in AβPP/PS1 Mice.
Volume: 97
Issue: 2
Pages: 855-870
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Publication
21109328 | J:188223
First Author: Rey NL
Year: 2012
Journal: Neurobiol Aging
Title: Locus coeruleus degeneration exacerbates olfactory deficits in APP/PS1 transgenic mice.
Volume: 33
Issue: 2
Pages: 426.e1-11
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Publication
21513747 | J:172201
First Author: Zhang W
Year: 2011
Journal: Behav Brain Res
Title: Soluble Aβ levels correlate with cognitive deficits in the 12-month-old APPswe/PS1dE9 mouse model of Alzheimer's disease.
Volume: 222
Issue: 2
Pages: 342-50
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Publication
26865611 | J:231623
First Author: Harris RA
Year: 2016
Journal: J Neurosci
Title: Aerobic Glycolysis in the Frontal Cortex Correlates with Memory Performance in Wild-Type Mice But Not the APP/PS1 Mouse Model of Cerebral Amyloidosis.
Volume: 36
Issue: 6
Pages: 1871-8
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Publication
22418058 | J:183242
 
First Author: Hamilton A
Year: 2012
Journal: Brain Res
Title: The effect of ageing on neurogenesis and oxidative stress in the APP(swe)/PS1(deltaE9) mouse model of Alzheimer's disease.
Volume: 1449
Pages: 83-93
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Publication
23419740 | J:197461
 
First Author: Cheng D
Year: 2013
Journal: Behav Brain Res
Title: Novel behavioural characteristics of the APP(Swe)/PS1ΔE9 transgenic mouse model of Alzheimer's disease.
Volume: 245
Pages: 120-7
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Publication
34450329 | J:350054
 
First Author: Wilcox JM
Year: 2021
Journal: Neurobiol Dis
Title: Altered synaptic glutamate homeostasis contributes to cognitive decline in young APP/PSEN1 mice.
Volume: 158
Pages: 105486
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Publication
18430735 | J:138568
First Author: Shimojo M
Year: 2008
Journal: J Biol Chem
Title: Enzymatic characteristics of I213T mutant presenilin-1/gamma-secretase in cell models and knock-in mouse brains: familial Alzheimer disease-linked mutation impairs gamma-site cleavage of amyloid precursor protein C-terminal fragment beta.
Volume: 283
Issue: 24
Pages: 16488-96
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Publication
26438723 | J:227775
First Author: Ben-Gedalya T
Year: 2015
Journal: EMBO J
Title: Alzheimer's disease-causing proline substitutions lead to presenilin 1 aggregation and malfunction.
Volume: 34
Issue: 22
Pages: 2820-39
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Publication
19376115 | J:148014
First Author: Suzuki Y
Year: 2009
Journal: FEBS Lett
Title: An alternative spliced mouse presenilin-2 mRNA encodes a novel gamma-secretase inhibitor.
Volume: 583
Issue: 9
Pages: 1403-8
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Publication
21206757 | J:168322
First Author: Jayadev S
Year: 2010
Journal: PLoS One
Title: Presenilin 2 is the predominant γ-secretase in microglia and modulates cytokine release.
Volume: 5
Issue: 12
Pages: e15743
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Publication
15280425 | J:92071
First Author: Gowrishankar K
Year: 2004
Journal: J Cell Sci
Title: Release of a membrane-bound death domain by gamma-secretase processing of the p75NTR homolog NRADD.
Volume: 117
Issue: Pt 18
Pages: 4099-111
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Publication
11719200 | J:73169
First Author: Annaert WG
Year: 2001
Journal: Neuron
Title: Interaction with telencephalin and the amyloid precursor protein predicts a ring structure for presenilins.
Volume: 32
Issue: 4
Pages: 579-89
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Publication
20674680 | J:164909
First Author: Sanjo N
Year: 2010
Journal: Neurosci Lett
Title: Localization and trafficking of endogenous anterior pharynx-defective 1, a component of Alzheimer's disease related gamma-secretase.
Volume: 483
Issue: 1
Pages: 53-6
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Publication
16449386 | J:248239
First Author: Cai D
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Presenilin-1 uses phospholipase D1 as a negative regulator of beta-amyloid formation.
Volume: 103
Issue: 6
Pages: 1941-6
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Publication
10662508 | J:60346
First Author: Nowotny P
Year: 2000
Journal: Mol Cell Neurosci
Title: Posttranslational modification and plasma membrane localization of the Drosophila melanogaster presenilin.
Volume: 15
Issue: 1
Pages: 88-98
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Publication
9246482 | J:46334
 
First Author: Sr George-Hyslop PH
Year: 1996
Journal: Cold Spring Harb Symp Quant Biol
Title: Two homologous genes causing early-onset familial Alzheimer's disease.
Volume: 61
Pages: 559-64
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10193895 | J:54166
First Author: Seabrook GR
Year: 1999
Journal: Neuropharmacology
Title: Transgenic animals relevant to Alzheimer's disease.
Volume: 38
Issue: 1
Pages: 1-17
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Publication
15379903 | J:93286
First Author: Ilaya NT
Year: 2004
Journal: J Neurochem
Title: Nicastrin expression in mouse peripheral tissues is not co-ordinated with presenilin and is high in muscle.
Volume: 91
Issue: 1
Pages: 230-7
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Publication
18367332 | J:136646
First Author: Dehvari N
Year: 2008
Journal: Neurosci Lett
Title: Presenilin regulates extracellular regulated kinase (Erk) activity by a protein kinase C alpha dependent mechanism.
Volume: 436
Issue: 1
Pages: 77-80
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Publication
19920078 | J:155566
First Author: Ono Y
Year: 2009
Journal: J Cell Sci
Title: Presenilin-1 acts via Id1 to regulate the function of muscle satellite cells in a gamma-secretase-independent manner.
Volume: 122
Issue: Pt 24
Pages: 4427-38
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Publication
21285369 | J:169222
First Author: Zampese E
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Presenilin 2 modulates endoplasmic reticulum (ER)-mitochondria interactions and Ca2+ cross-talk.
Volume: 108
Issue: 7
Pages: 2777-82
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Publication
22002539 | J:180062
First Author: Ohki Y
Year: 2011
Journal: EMBO J
Title: Phenylpiperidine-type γ-secretase modulators target the transmembrane domain 1 of presenilin 1.
Volume: 30
Issue: 23
Pages: 4815-24
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Publication
22505025 | J:184696
First Author: Chávez-Gutiérrez L
Year: 2012
Journal: EMBO J
Title: The mechanism of γ-Secretase dysfunction in familial Alzheimer disease.
Volume: 31
Issue: 10
Pages: 2261-74
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Publication
22796216 | J:188047
First Author: Kumar A
Year: 2012
Journal: Neurochem Int
Title: Presenilin 1 and 2 are expressed differentially in the cerebral cortex of mice during development.
Volume: 61
Issue: 5
Pages: 778-82
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Publication
26923592 | J:234362
First Author: Reddy K
Year: 2016
Journal: Cell Rep
Title: Dysregulation of Nutrient Sensing and CLEARance in Presenilin Deficiency.
Volume: 14
Issue: 9
Pages: 2166-2179
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Publication
27810638 | J:239687
 
First Author: Wang W
Year: 2017
Journal: Neurobiol Aging
Title: Presenilin 1 mutations influence processing and trafficking of the ApoE receptor apoER2.
Volume: 49
Pages: 145-153
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Publication
29880815 | J:262580
First Author: Zoltowska KM
Year: 2018
Journal: Sci Rep
Title: Novel interaction between Alzheimer's disease-related protein presenilin 1 and glutamate transporter 1.
Volume: 8
Issue: 1
Pages: 8718
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Publication
28879407 | J:315890
First Author: Ham S
Year: 2018
Journal: Mol Neurobiol
Title: MicroRNA Profiling in Aging Brain of PSEN1/PSEN2 Double Knockout Mice.
Volume: 55
Issue: 6
Pages: 5232-5242
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Publication
26317549 | J:318350
First Author: Wang F
Year: 2015
Journal: Oncotarget
Title: Splenocytes derived from young WT mice prevent AD progression in APPswe/PSENldE9 transgenic mice.
Volume: 6
Issue: 25
Pages: 20851-62
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Publication
24025330 | J:320751
First Author: Xuan Z
Year: 2013
Journal: J Biol Chem
Title: Presenilin-1/γ-secretase controls glutamate release, tyrosine phosphorylation, and surface expression of N-methyl-D-aspartate receptor (NMDAR) subunit GluN2B.
Volume: 288
Issue: 42
Pages: 30495-30501
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Publication
22036569 | J:178689
First Author: Wu J
Year: 2011
Journal: Cell
Title: Arc/Arg3.1 regulates an endosomal pathway essential for activity-dependent β-amyloid generation.
Volume: 147
Issue: 3
Pages: 615-28
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Publication
12794186 | J:84628
First Author: Six E
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: The Notch ligand Delta1 is sequentially cleaved by an ADAM protease and gamma-secretase.
Volume: 100
Issue: 13
Pages: 7638-43
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11435709 | J:70475
First Author: Kennell JA
Year: 2001
Journal: Cytogenet Cell Genet
Title: cDNA cloning, chromosomal localization and evolutionary analysis of mouse vacuolar ATPase subunit D, Atp6m.
Volume: 92
Issue: 3-4
Pages: 337-41
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Publication
22715045 | J:244939
First Author: Lee D
Year: 2012
Journal: Synapse
Title: Presenilin conditional double knockout mice exhibit decreases in drebrin a at hippocampal CA1 synapses.
Volume: 66
Issue: 10
Pages: 870-9
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Publication
24916066 | J:310292
 
First Author: Niedowicz DM
Year: 2014
Journal: Acta Neuropathol Commun
Title: Obesity and diabetes cause cognitive dysfunction in the absence of accelerated β-amyloid deposition in a novel murine model of mixed or vascular dementia.
Volume: 2
Pages: 64
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31034991 | J:277797
First Author: Zhang L
Year: 2019
Journal: Biochim Biophys Acta Mol Basis Dis
Title: The db mutation improves memory in younger mice in a model of Alzheimer's disease.
Volume: 1865
Issue: 9
Pages: 2157-2167
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22514046 | J:188080
First Author: Drummond ES
Year: 2012
Journal: Endocrinology
Title: Altered expression of Alzheimer's disease-related proteins in male hypogonadal mice.
Volume: 153
Issue: 6
Pages: 2789-99
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18776935 | J:143942
First Author: Xu G
Year: 2008
Journal: PLoS One
Title: Receptor-associated protein (RAP) plays a central role in modulating Abeta deposition in APP/PS1 transgenic mice.
Volume: 3
Issue: 9
Pages: e3159
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Publication
16006137 | J:104654
First Author: Mirnics ZK
Year: 2005
Journal: Neurobiol Dis
Title: P75 neurotrophin receptor regulates expression of neural cell adhesion molecule 1.
Volume: 20
Issue: 3
Pages: 969-85
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17626125 | J:124699
First Author: Bearden SE
Year: 2007
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Advancing age produces sex differences in vasomotor kinetics during and after skeletal muscle contraction.
Volume: 293
Issue: 3
Pages: R1274-9
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12843267 | J:84370
First Author: Burns M
Year: 2003
Journal: J Neurosci
Title: Presenilin redistribution associated with aberrant cholesterol transport enhances beta-amyloid production in vivo.
Volume: 23
Issue: 13
Pages: 5645-9
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16377636 | J:108326
First Author: Tanemura K
Year: 2006
Journal: J Biol Chem
Title: Formation of tau inclusions in knock-in mice with familial Alzheimer disease (FAD) mutation of presenilin 1 (PS1).
Volume: 281
Issue: 8
Pages: 5037-41
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Publication
19665542 | J:157272
First Author: Nakajima M
Year: 2009
Journal: Int J Dev Neurosci
Title: Restricted growth and insulin-like growth factor-1 deficiency in mice lacking presenilin-1 in the neural crest cell lineage.
Volume: 27
Issue: 8
Pages: 837-43
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23382946 | J:195914
First Author: Paine SM
Year: 2013
Journal: PLoS One
Title: Pale body-like inclusion formation and neurodegeneration following depletion of 26S proteasomes in mouse brain neurones are independent of α-synuclein.
Volume: 8
Issue: 1
Pages: e54711
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17556541 | J:122380
First Author: Zhang YW
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Presenilin/gamma-secretase-dependent processing of beta-amyloid precursor protein regulates EGF receptor expression.
Volume: 104
Issue: 25
Pages: 10613-8
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15122901 | J:115485
First Author: Qyang Y
Year: 2004
Journal: Biochemistry
Title: Myeloproliferative disease in mice with reduced presenilin gene dosage: effect of gamma-secretase blockage.
Volume: 43
Issue: 18
Pages: 5352-9
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16449385 | J:106075
First Author: Cai D
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Phospholipase D1 corrects impaired betaAPP trafficking and neurite outgrowth in familial Alzheimer's disease-linked presenilin-1 mutant neurons.
Volume: 103
Issue: 6
Pages: 1936-40
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21910732 | J:178371
First Author: Kim J
Year: 2011
Journal: J Neurochem
Title: Characterization of nectin processing mediated by presenilin-dependent γ-secretase.
Volume: 119
Issue: 5
Pages: 945-56
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18195359 | J:131284
First Author: Yagi T
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Defective signal transduction in B lymphocytes lacking presenilin proteins.
Volume: 105
Issue: 3
Pages: 979-84
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11740561 | J:73257
First Author: Kamal A
Year: 2001
Journal: Nature
Title: Kinesin-mediated axonal transport of a membrane compartment containing beta-secretase and presenilin-1 requires APP.
Volume: 414
Issue: 6864
Pages: 643-8
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Publication
27240887 | J:254080
 
First Author: Cras-Méneur C
Year: 2016
Journal: Sci Rep
Title: Early pancreatic islet fate and maturation is controlled through RBP-Jκ.
Volume: 6
Pages: 26874
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18665263 | J:139496
First Author: Ong CT
Year: 2008
Journal: PLoS One
Title: Notch and presenilin regulate cellular expansion and cytokine secretion but cannot instruct Th1/Th2 fate acquisition.
Volume: 3
Issue: 7
Pages: e2823
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Publication
22475621 | J:194441
First Author: Barthet G
Year: 2013
Journal: Neurobiol Aging
Title: Presenilin mediates neuroprotective functions of ephrinB and brain-derived neurotrophic factor and regulates ligand-induced internalization and metabolism of EphB2 and TrkB receptors.
Volume: 34
Issue: 2
Pages: 499-510
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Publication
24304563 | J:220298
First Author: Robinson A
Year: 2014
Journal: Aging Cell
Title: Upregulation of PGC-1α expression by Alzheimer's disease-associated pathway: presenilin 1/amyloid precursor protein (APP)/intracellular domain of APP.
Volume: 13
Issue: 2
Pages: 263-72
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Publication
19494151 | J:149506
First Author: Tabuchi K
Year: 2009
Journal: J Neurosci
Title: Conditional forebrain inactivation of nicastrin causes progressive memory impairment and age-related neurodegeneration.
Volume: 29
Issue: 22
Pages: 7290-301
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Publication
15345711 | J:94484
First Author: Beglopoulos V
Year: 2004
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