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Search results 1101 to 1200 out of 5246 for App

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Category: Publication
Type Details Score
Publication
First Author: Xia X
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: The aspartate-257 of presenilin 1 is indispensable for mouse development and production of beta-amyloid peptides through beta-catenin-independent mechanisms.
Volume: 99
Issue: 13
Pages: 8760-5
Publication
First Author: Bao J
Year: 2007
Journal: Mol Cell Biol
Title: Suppression of beta-amyloid precursor protein signaling into the nucleus by estrogens mediated through complex formation between the estrogen receptor and Fe65.
Volume: 27
Issue: 4
Pages: 1321-33
Publication
First Author: Wang H
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: SLP-76-ADAP adaptor module regulates LFA-1 mediated costimulation and T cell motility.
Volume: 106
Issue: 30
Pages: 12436-41
Publication
First Author: Potter AS
Year: 2015
Journal: PLoS One
Title: Molecular Anatomy of Palate Development.
Volume: 10
Issue: 7
Pages: e0132662
Publication
First Author: Guan PP
Year: 2019
Journal: Cell Mol Immunol
Title: Cyclooxygenase-2 is critical for the propagation of β-amyloid protein and reducing the glycosylation of tau in Alzheimer's disease.
Volume: 16
Issue: 11
Pages: 892-894
Publication
First Author: Li J
Year: 2020
Journal: Aging (Albany NY)
Title: MicroRNA-338-5p alleviates neuronal apoptosis via directly targeting BCL2L11 in APP/PS1 mice.
Volume: 12
Issue: 20
Pages: 20728-20742
Publication  
First Author: Guenet JL
Year: 1988
Journal: Mouse News Lett
Title: Changed gene symbols: Adap changed to App; Acetylcholine receptor symbol changes
Volume: 80
Pages: 5
Publication
First Author: Tamboli IY
Year: 2008
Journal: J Neurosci
Title: Loss of gamma-secretase function impairs endocytosis of lipoprotein particles and membrane cholesterol homeostasis.
Volume: 28
Issue: 46
Pages: 12097-106
Publication
First Author: Pardossi-Piquard R
Year: 2005
Journal: Neuron
Title: Presenilin-dependent transcriptional control of the Abeta-degrading enzyme neprilysin by intracellular domains of betaAPP and APLP.
Volume: 46
Issue: 4
Pages: 541-54
Publication
First Author: Lorent K
Year: 1995
Journal: Neuroscience
Title: Expression in mouse embryos and in adult mouse brain of three members of the amyloid precursor protein family, of the alpha-2-macroglobulin receptor/low density lipoprotein receptor-related protein and of its ligands apolipoprotein E, lipoprotein lipase, alpha-2-macroglobulin and the 40,000 molecular weight receptor-associated protein.
Volume: 65
Issue: 4
Pages: 1009-25
Publication
First Author: Varvel NH
Year: 2009
Journal: J Clin Invest
Title: NSAIDs prevent, but do not reverse, neuronal cell cycle reentry in a mouse model of Alzheimer disease.
Volume: 119
Issue: 12
Pages: 3692-702
Publication
First Author: Cai H
Year: 2001
Journal: Nat Neurosci
Title: BACE1 is the major beta-secretase for generation of Abeta peptides by neurons.
Volume: 4
Issue: 3
Pages: 233-4
Publication
First Author: Hu X
Year: 2013
Journal: Cell Rep
Title: BACE1 regulates hippocampal astrogenesis via the Jagged1-Notch pathway.
Volume: 4
Issue: 1
Pages: 40-9
Publication
First Author: Kuhn PH
Year: 2012
Journal: EMBO J
Title: Secretome protein enrichment identifies physiological BACE1 protease substrates in neurons.
Volume: 31
Issue: 14
Pages: 3157-68
Publication
First Author: Hu X
Year: 2008
Journal: FASEB J
Title: Genetic deletion of BACE1 in mice affects remyelination of sciatic nerves.
Volume: 22
Issue: 8
Pages: 2970-80
Publication
First Author: Herber J
Year: 2018
Journal: Mol Cell Proteomics
Title: Click Chemistry-mediated Biotinylation Reveals a Function for the Protease BACE1 in Modulating the Neuronal Surface Glycoproteome.
Volume: 17
Issue: 8
Pages: 1487-1501
Publication
First Author: Müller SA
Year: 2023
Journal: Mol Neurodegener
Title: The Alzheimer's disease-linked protease BACE1 modulates neuronal IL-6 signaling through shedding of the receptor gp130.
Volume: 18
Issue: 1
Pages: 13
Publication
First Author: Hu X
Year: 2006
Journal: Nat Neurosci
Title: Bace1 modulates myelination in the central and peripheral nervous system.
Volume: 9
Issue: 12
Pages: 1520-5
Publication
First Author: Heindl M
Year: 2015
Journal: PLoS One
Title: Loss of Bace1 in mice does not alter the severity of caerulein induced pancreatitis.
Volume: 10
Issue: 5
Pages: e0125556
Publication
First Author: Hu X
Year: 2017
Journal: Glia
Title: BACE1 regulates the proliferation and cellular functions of Schwann cells.
Volume: 65
Issue: 5
Pages: 712-726
Publication    
First Author: Kim W
Year: 2021
Journal: J Biol Chem
Title: Spatiotemporal processing of neural cell adhesion molecules 1 and 2 by BACE1 in vivo.
Pages: 100372
Publication
First Author: Wang H
Year: 2014
Journal: PLoS One
Title: Postsynaptic target specific synaptic dysfunctions in the CA3 area of BACE1 knockout mice.
Volume: 9
Issue: 3
Pages: e92279
Publication
First Author: Wang H
Year: 2008
Journal: J Neurosci
Title: BACE1 knock-outs display deficits in activity-dependent potentiation of synaptic transmission at mossy fiber to CA3 synapses in the hippocampus.
Volume: 28
Issue: 35
Pages: 8677-81
Publication
First Author: Hou H
Year: 2017
Journal: Stem Cell Reports
Title: BACE1 Deficiency Causes Abnormal Neuronal Clustering in the Dentate Gyrus.
Volume: 9
Issue: 1
Pages: 217-230
Publication
First Author: Stertz L
Year: 2018
Journal: Mol Neurobiol
Title: BACE1-Deficient Mice Exhibit Alterations in Immune System Pathways.
Volume: 55
Issue: 1
Pages: 709-717
Publication
First Author: Paredes RM
Year: 2015
Journal: Genes Brain Behav
Title: Physiological and behavioral effects of amphetamine in BACE1(-/-) mice.
Volume: 14
Issue: 5
Pages: 411-8
Publication  
First Author: Chatila ZK
Year: 2018
Journal: eNeuro
Title: BACE1 Regulates Proliferation and Neuronal Differentiation of Newborn Cells in the Adult Hippocampus in Mice.
Volume: 5
Issue: 4
Publication  
First Author: Hitt BD
Year: 2010
Journal: Mol Neurodegener
Title: BACE1-/- mice exhibit seizure activity that does not correlate with sodium channel level or axonal localization.
Volume: 5
Pages: 31
Publication
First Author: Hu X
Year: 2010
Journal: J Neurosci
Title: BACE1 deficiency causes altered neuronal activity and neurodegeneration.
Volume: 30
Issue: 26
Pages: 8819-29
Publication
First Author: Benoit MR
Year: 2023
Journal: Hum Mol Genet
Title: Postnatal neuronal Bace1 deletion impairs neuroblast and oligodendrocyte maturation.
Volume: 32
Issue: 7
Pages: 1193-1207
Publication
First Author: Ferrer I
Year: 2005
Journal: Hum Mol Genet
Title: Inactivation of the peroxisomal ABCD2 transporter in the mouse leads to late-onset ataxia involving mitochondria, Golgi and endoplasmic reticulum damage.
Volume: 14
Issue: 23
Pages: 3565-77
Publication
First Author: Purohit AA
Year: 2012
Journal: J Biol Chem
Title: Down syndrome cell adhesion molecule (DSCAM) associates with uncoordinated-5C (UNC5C) in netrin-1-mediated growth cone collapse.
Volume: 287
Issue: 32
Pages: 27126-38
Publication
First Author: Mock BA
Year: 1995
Journal: Genomics
Title: CHUK, a conserved helix-loop-helix ubiquitous kinase, maps to human chromosome 10 and mouse chromosome 19.
Volume: 27
Issue: 2
Pages: 348-51
Publication
First Author: Reeves RH
Year: 1989
Journal: Genomics
Title: The mouse neurological mutant weaver maps within the region of chromosome 16 that is homologous to human chromosome 21.
Volume: 5
Issue: 3
Pages: 522-6
Publication
First Author: Dulabon L
Year: 2000
Journal: Neuron
Title: Reelin binds alpha3beta1 integrin and inhibits neuronal migration.
Volume: 27
Issue: 1
Pages: 33-44
Publication
First Author: Deane R
Year: 2008
Journal: J Clin Invest
Title: apoE isoform-specific disruption of amyloid beta peptide clearance from mouse brain.
Volume: 118
Issue: 12
Pages: 4002-13
Publication
First Author: Um JW
Year: 2012
Journal: Nat Neurosci
Title: Alzheimer amyloid-β oligomer bound to postsynaptic prion protein activates Fyn to impair neurons.
Volume: 15
Issue: 9
Pages: 1227-35
Publication
First Author: Moore KJ
Year: 2002
Journal: J Biol Chem
Title: A CD36-initiated signaling cascade mediates inflammatory effects of beta-amyloid.
Volume: 277
Issue: 49
Pages: 47373-9
Publication
First Author: Zhang Y
Year: 2018
Journal: Aging Cell
Title: nNOS-CAPON interaction mediates amyloid-β-induced neurotoxicity, especially in the early stages.
Volume: 17
Issue: 3
Pages: e12754
Publication
First Author: Yang Y
Year: 2004
Journal: J Neurochem
Title: Presenilin-1 and intracellular calcium stores regulate neuronal glutamate uptake.
Volume: 88
Issue: 6
Pages: 1361-72
Publication
First Author: Miyamoto T
Year: 2016
Journal: J Biol Chem
Title: Increasing the Receptor Tyrosine Kinase EphB2 Prevents Amyloid-β-induced Depletion of Cell Surface Glutamate Receptors by a Mechanism That Requires the PDZ-binding Motif of EphB2 and Neuronal Activity.
Volume: 291
Issue: 4
Pages: 1719-1734
Publication
First Author: De Schepper S
Year: 2023
Journal: Nat Neurosci
Title: Perivascular cells induce microglial phagocytic states and synaptic engulfment via SPP1 in mouse models of Alzheimer's disease.
Volume: 26
Issue: 3
Pages: 406-415
Publication
First Author: Eckman EA
Year: 2006
Journal: J Biol Chem
Title: Regulation of steady-state beta-amyloid levels in the brain by neprilysin and endothelin-converting enzyme but not angiotensin-converting enzyme.
Volume: 281
Issue: 41
Pages: 30471-8
Publication
First Author: Krohn M
Year: 2011
Journal: J Clin Invest
Title: Cerebral amyloid-β proteostasis is regulated by the membrane transport protein ABCC1 in mice.
Volume: 121
Issue: 10
Pages: 3924-31
Publication  
First Author: Srinivasan S
Year: 2024
Journal: Front Immunol
Title: Inflammasome signaling is dispensable for ß-amyloid-induced neuropathology in preclinical models of Alzheimer's disease.
Volume: 15
Pages: 1323409
Publication
First Author: Ittner A
Year: 2016
Journal: Science
Title: Site-specific phosphorylation of tau inhibits amyloid-β toxicity in Alzheimer's mice.
Volume: 354
Issue: 6314
Pages: 904-908
Publication
First Author: Yang S
Year: 2024
Journal: Mol Neurodegener
Title: NMNAT2 supports vesicular glycolysis via NAD homeostasis to fuel fast axonal transport.
Volume: 19
Issue: 1
Pages: 13
Publication
First Author: Eftekharzadeh B
Year: 2018
Journal: Neuron
Title: Tau Protein Disrupts Nucleocytoplasmic Transport in Alzheimer's Disease.
Volume: 99
Issue: 5
Pages: 925-940.e7
Publication
First Author: Nies SH
Year: 2021
Journal: J Biol Chem
Title: Spreading of Alzheimer tau seeds is enhanced by aging and template matching with limited impact of amyloid-β.
Volume: 297
Issue: 4
Pages: 101159
Publication
First Author: Yi C
Year: 2016
Journal: Cell Death Differ
Title: Astroglial connexin43 contributes to neuronal suffering in a mouse model of Alzheimer's disease.
Volume: 23
Issue: 10
Pages: 1691-701
Publication
First Author: Li L
Year: 2020
Journal: Hum Mol Genet
Title: Reduction of Tet2 exacerbates early stage Alzheimer's pathology and cognitive impairments in 2×Tg-AD mice.
Volume: 29
Issue: 11
Pages: 1833-1852
Publication
First Author: Nakanishi N
Year: 2013
Journal: J Neurosci
Title: Synaptic protein α1-takusan mitigates amyloid-β-induced synaptic loss via interaction with tau and postsynaptic density-95 at postsynaptic sites.
Volume: 33
Issue: 35
Pages: 14170-83
Publication
First Author: Sevalle J
Year: 2009
Journal: J Neurochem
Title: Pharmacological evidences for DFK167-sensitive presenilin-independent gamma-secretase-like activity.
Volume: 110
Issue: 1
Pages: 275-83
Publication
First Author: Stemmer N
Year: 2013
Journal: PLoS One
Title: Generation of amyloid-β is reduced by the interaction of calreticulin with amyloid precursor protein, presenilin and nicastrin.
Volume: 8
Issue: 4
Pages: e61299
Publication
First Author: Reeves RH
Year: 1987
Journal: Brain Res
Title: Genetic linkage in the mouse of genes involved in Down syndrome and Alzheimer's disease in man.
Volume: 388
Issue: 3
Pages: 215-21
Publication
First Author: Irving NG
Year: 1989
Journal: Cytogenet Cell Genet
Title: The alpha 2 chain of type 1 collagen does not map to mouse chromosome 16 but maps close to the Met proto-oncogene on mouse chromosome 6.
Volume: 50
Issue: 2-3
Pages: 121-2
Publication
First Author: Irving NG
Year: 1991
Journal: Genomics
Title: The multipoint genetic mapping of mouse chromosome 16.
Volume: 9
Issue: 2
Pages: 386-9
Publication
First Author: Reeves RH
Year: 1990
Journal: Genomics
Title: Sex, strain, and species differences affect recombination across an evolutionarily conserved segment of mouse chromosome 16.
Volume: 8
Issue: 1
Pages: 141-8
Publication
First Author: Irving NG
Year: 1991
Journal: Genomics
Title: Mouse chromosome-specific markers generated by PCR and their mapping through interspecific backcrosses.
Volume: 11
Issue: 3
Pages: 679-86
Publication
First Author: Irving NG
Year: 1993
Journal: Mamm Genome
Title: The positions of 12 simple sequence repeat markers relative to reference loci on mouse chromosome 16.
Volume: 4
Issue: 7
Pages: 364-7
Publication
First Author: Mjaatvedt AE
Year: 1993
Journal: Genomics
Title: High-resolution mapping of D16led-1, Gart, Gas-4, Cbr, Pcp-4, and Erg on distal mouse chromosome 16.
Volume: 17
Issue: 2
Pages: 382-6
Publication
First Author: Pericak-Vance MA
Year: 1995
Journal: Trends Genet
Title: Genetic susceptibility to Alzheimer disease.
Volume: 11
Issue: 12
Pages: 504-8
Publication
First Author: Mariano TM
Year: 1996
Journal: Mamm Genome
Title: Genetic mapping of the gene for the mouse interferon-gamma receptor signaling subunit to the distal end of chromosome 16.
Volume: 7
Issue: 4
Pages: 321-2
Publication  
First Author: Price DL
Year: 1998
Journal: Annu Rev Genet
Title: Alzheimer's disease: genetic studies and transgenic models.
Volume: 32
Pages: 461-93
Publication
First Author: Vetrivel KS
Year: 2008
Journal: J Biol Chem
Title: Evidence that CD147 modulation of beta-amyloid (Abeta) levels is mediated by extracellular degradation of secreted Abeta.
Volume: 283
Issue: 28
Pages: 19489-98
Publication
First Author: Green KN
Year: 2008
Journal: J Cell Biol
Title: SERCA pump activity is physiologically regulated by presenilin and regulates amyloid beta production.
Volume: 181
Issue: 7
Pages: 1107-16
Publication
First Author: Li L
Year: 2010
Journal: Neuropharmacology
Title: DHEA prevents Aβ25-35-impaired survival of newborn neurons in the dentate gyrus through a modulation of PI3K-Akt-mTOR signaling.
Volume: 59
Issue: 4-5
Pages: 323-33
Publication  
First Author: Reeves RH
Year: 1987
Journal: Cytogenet Cell Genet
Title: Genetic and cytologic localization of genes related to Down syndrome and Alzheimer's disease in the mouse.
Volume: 46
Pages: 681 (Abstr.)
Publication
First Author: Roffler-Tarlov S
Year: 1994
Journal: Neurodegeneration
Title: The chromosomal location of the murine mutation weaver.
Volume: 3
Issue: 1
Pages: 61-72
Publication
First Author: Yáñez MJ
Year: 2016
Journal: Biochim Biophys Acta
Title: c-Abl links APP-BACE1 interaction promoting APP amyloidogenic processing in Niemann-Pick type C disease.
Volume: 1862
Issue: 11
Pages: 2158-2167
Publication  
First Author: Frederikse PH
Year: 2004
Journal: Mol Vis
Title: Synapsin and synaptic vesicle protein expression during embryonic and post-natal lens fiber cell differentiation.
Volume: 10
Pages: 794-804
Publication
First Author: Patarca R
Year: 1989
Journal: J Exp Med
Title: Structural and functional studies of the early T lymphocyte activation 1 (Eta-1) gene. Definition of a novel T cell-dependent response associated with genetic resistance to bacterial infection.
Volume: 170
Issue: 1
Pages: 145-61
Publication
First Author: Simpson MT
Year: 2001
Journal: J Neurosci
Title: Caspase 3 deficiency rescues peripheral nervous system defect in retinoblastoma nullizygous mice.
Volume: 21
Issue: 18
Pages: 7089-98
Publication
First Author: Kuwako K
Year: 2005
Journal: J Neurosci
Title: Disruption of the paternal necdin gene diminishes TrkA signaling for sensory neuron survival.
Volume: 25
Issue: 30
Pages: 7090-9
Publication
First Author: Stupack J
Year: 2020
Journal: J Neurosci
Title: Soluble SORLA Enhances Neurite Outgrowth and Regeneration through Activation of the EGF Receptor/ERK Signaling Axis.
Volume: 40
Issue: 31
Pages: 5908-5921
Publication
First Author: Batiuk MY
Year: 2017
Journal: J Biol Chem
Title: An immunoaffinity-based method for isolating ultrapure adult astrocytes based on ATP1B2 targeting by the ACSA-2 antibody.
Volume: 292
Issue: 21
Pages: 8874-8891
Publication
First Author: Schibler L
Year: 1998
Journal: Genome Res
Title: Comparative gene mapping: a fine-scale survey of chromosome rearrangements between ruminants and humans.
Volume: 8
Issue: 9
Pages: 901-15
Publication
First Author: Almenar-Queralt A
Year: 2013
Journal: J Biol Chem
Title: Presenilins regulate neurotrypsin gene expression and neurotrypsin-dependent agrin cleavage via cyclic AMP response element-binding protein (CREB) modulation.
Volume: 288
Issue: 49
Pages: 35222-36
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication
First Author: de la Brousse FC
Year: 1994
Journal: Genes Dev
Title: Molecular and genetic characterization of GABP beta.
Volume: 8
Issue: 15
Pages: 1853-65
Publication
First Author: Bae SC
Year: 1994
Journal: Mol Cell Biol
Title: PEBP2 alpha B/mouse AML1 consists of multiple isoforms that possess differential transactivation potentials.
Volume: 14
Issue: 5
Pages: 3242-52
Publication
First Author: Fan CM
Year: 1996
Journal: Mol Cell Neurosci
Title: Expression patterns of two murine homologs of Drosophila single-minded suggest possible roles in embryonic patterning and in the pathogenesis of Down syndrome.
Volume: 7
Issue: 1
Pages: 1-16
Publication
First Author: Murphy WJ
Year: 2001
Journal: Nature
Title: Molecular phylogenetics and the origins of placental mammals.
Volume: 409
Issue: 6820
Pages: 614-8
Publication
First Author: Gyllborg D
Year: 2018
Journal: Stem Cell Reports
Title: The Matricellular Protein R-Spondin 2 Promotes Midbrain Dopaminergic Neurogenesis and Differentiation.
Volume: 11
Issue: 3
Pages: 651-664
Publication  
First Author: Zindel J
Year: 2021
Journal: Science
Title: Primordial GATA6 macrophages function as extravascular platelets in sterile injury.
Volume: 371
Issue: 6533
Publication
First Author: Merte J
Year: 2010
Journal: Nat Cell Biol
Title: Sec24b selectively sorts Vangl2 to regulate planar cell polarity during neural tube closure.
Volume: 12
Issue: 1
Pages: 41-6; sup pp 1-8
Publication
First Author: Yamasaki T
Year: 2017
Journal: Sci Rep
Title: Age-dependent motor dysfunction due to neuron-specific disruption of stress-activated protein kinase MKK7.
Volume: 7
Issue: 1
Pages: 7348
Publication
First Author: Wang X
Year: 2003
Journal: Genome Res
Title: Using advanced intercross lines for high-resolution mapping of HDL cholesterol quantitative trait loci.
Volume: 13
Issue: 7
Pages: 1654-64
Publication
First Author: Forni PE
Year: 2011
Journal: J Neurosci
Title: A role for FE65 in controlling GnRH-1 neurogenesis.
Volume: 31
Issue: 2
Pages: 480-91
Publication  
First Author: Liu L
Year: 2016
Journal: Neuroscience
Title: Neuronal expression of ILEI/FAM3C and its reduction in Alzheimer's disease.
Volume: 330
Pages: 236-46
Publication
First Author: Zeng F
Year: 2019
Journal: PLoS Biol
Title: The deubiquitinase USP6 affects memory and synaptic plasticity through modulating NMDA receptor stability.
Volume: 17
Issue: 12
Pages: e3000525
Publication      
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication
First Author: Hikake T
Year: 2003
Journal: Anat Embryol (Berl)
Title: Comparison of expression patterns between CREB family transcription factor OASIS and proteoglycan core protein genes during murine tooth development.
Volume: 206
Issue: 5
Pages: 373-80
Publication  
First Author: Pla P
Year: 2008
Journal: Neural Dev
Title: Identification of Phox2b-regulated genes by expression profiling of cranial motoneuron precursors.
Volume: 3
Pages: 14
Publication
First Author: Xia D
Year: 2015
Journal: Neuron
Title: Presenilin-1 knockin mice reveal loss-of-function mechanism for familial Alzheimer's disease.
Volume: 85
Issue: 5
Pages: 967-81
Publication  
First Author: Xia Y
Year: 2022
Journal: Development
Title: Presenilin enhancer 2 is crucial for the transition of apical progenitors into neurons but into not basal progenitors in the developing hippocampus.
Volume: 149
Issue: 10
Publication
First Author: Esteve P
Year: 2011
Journal: Nat Neurosci
Title: SFRPs act as negative modulators of ADAM10 to regulate retinal neurogenesis.
Volume: 14
Issue: 5
Pages: 562-9
Publication
First Author: Berg JM
Year: 2015
Journal: Neuron
Title: JAKMIP1, a Novel Regulator of Neuronal Translation, Modulates Synaptic Function and Autistic-like Behaviors in Mouse.
Volume: 88
Issue: 6
Pages: 1173-91
Publication
First Author: Liu L
Year: 2015
Journal: J Neurochem
Title: Pre-synaptic localization of the γ-secretase-inhibiting protein p24α2 in the mammalian brain.
Volume: 133
Issue: 3
Pages: 422-31
Publication
First Author: Taylor BA
Year: 1995
Journal: Mamm Genome
Title: Typing recombinant inbred mouse strains for microsatellite markers on chromosomes 10, 16, 18, 19, and X.
Volume: 6
Issue: 8
Pages: 493-8