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Search results 1101 to 1200 out of 1419 for Pdx1

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Type Details Score
Publication
31270275 | J:277117
 
First Author: Panni RZ
Year: 2019
Journal: Sci Transl Med
Title: Agonism of CD11b reprograms innate immunity to sensitize pancreatic cancer to immunotherapies.
Volume: 11
Issue: 499
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Publication
26279302 | J:309335
First Author: Zhang S
Year: 2016
Journal: Oncogene
Title: Lunatic Fringe is a potent tumor suppressor in Kras-initiated pancreatic cancer.
Volume: 35
Issue: 19
Pages: 2485-95
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Publication
26151762 | J:225995
   
First Author: Krah NM
Year: 2015
Journal: Elife
Title: The acinar differentiation determinant PTF1A inhibits initiation of pancreatic ductal adenocarcinoma.
Volume: 4
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Publication
24305049 | J:207920
First Author: Rosenfeldt MT
Year: 2013
Journal: Nature
Title: p53 status determines the role of autophagy in pancreatic tumour development.
Volume: 504
Issue: 7479
Pages: 296-300
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Publication
39037766 | J:353863
First Author: Bermejo-Rodriguez C
Year: 2024
Journal: Cancer Res
Title: Scribble Deficiency Promotes Pancreatic Ductal Adenocarcinoma Development and Metastasis.
Volume: 84
Issue: 18
Pages: 2968-2984
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Publication
31534224 | J:280631
First Author: Morris JP 4th
Year: 2019
Journal: Nature
Title: α-Ketoglutarate links p53 to cell fate during tumour suppression.
Volume: 573
Issue: 7775
Pages: 595-599
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Publication
21266354 | J:169401
First Author: Timpson P
Year: 2011
Journal: Cancer Res
Title: Spatial regulation of RhoA activity during pancreatic cancer cell invasion driven by mutant p53.
Volume: 71
Issue: 3
Pages: 747-57
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Publication
22945649 | J:199980
First Author: Norris AM
Year: 2013
Journal: Oncogene
Title: AGR2 is a SMAD4-suppressible gene that modulates MUC1 levels and promotes the initiation and progression of pancreatic intraepithelial neoplasia.
Volume: 32
Issue: 33
Pages: 3867-76
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Publication
33127675 | J:313903
 
First Author: Rossi Sebastiano M
Year: 2020
Journal: Sci Adv
Title: ACSL3-PAI-1 signaling axis mediates tumor-stroma cross-talk promoting pancreatic cancer progression.
Volume: 6
Issue: 44
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Publication
24642931 | J:257234
 
First Author: Cruz-Monserrate Z
Year: 2014
Journal: Sci Rep
Title: Targeting pancreatic ductal adenocarcinoma acidic microenvironment.
Volume: 4
Pages: 4410
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Publication
37169967 | J:335562
     
First Author: Ely ZA
Year: 2023
Journal: Nat Biotechnol
Title: A prime editor mouse to model a broad spectrum of somatic mutations in vivo.
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Publication
31940491 | J:287255
First Author: Blagih J
Year: 2020
Journal: Cell Rep
Title: Cancer-Specific Loss of p53 Leads to a Modulation of Myeloid and T Cell Responses.
Volume: 30
Issue: 2
Pages: 481-496.e6
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Publication
26438692 | J:226536
First Author: Gopinathan A
Year: 2015
Journal: Dis Model Mech
Title: GEMMs as preclinical models for testing pancreatic cancer therapies.
Volume: 8
Issue: 10
Pages: 1185-200
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Publication
24362629 | J:208277
First Author: Mohseni M
Year: 2014
Journal: Nat Cell Biol
Title: A genetic screen identifies an LKB1-MARK signalling axis controlling the Hippo-YAP pathway.
Volume: 16
Issue: 1
Pages: 108-17
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Publication
24898060 | J:214456
First Author: Alderton GK
Year: 2014
Journal: Nat Rev Cancer
Title: Microenvironment: An exercise in restraint.
Volume: 14
Issue: 7
Pages: 449
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Publication
24784840 | J:212549
First Author: Park JW
Year: 2014
Journal: Mol Cancer Res
Title: Cooperativity of E-cadherin and Smad4 loss to promote diffuse-type gastric adenocarcinoma and metastasis.
Volume: 12
Issue: 8
Pages: 1088-99
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Publication
27506299 | J:310029
First Author: Grünwald B
Year: 2016
Journal: Gastroenterology
Title: Pancreatic Premalignant Lesions Secrete Tissue Inhibitor of Metalloproteinases-1, Which Activates Hepatic Stellate Cells Via CD63 Signaling to Create a Premetastatic Niche in the Liver.
Volume: 151
Issue: 5
Pages: 1011-1024.e7
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Publication
26929329 | J:230996
First Author: Saloman JL
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Ablation of sensory neurons in a genetic model of pancreatic ductal adenocarcinoma slows initiation and progression of cancer.
Volume: 113
Issue: 11
Pages: 3078-83
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Publication
32648540 | J:293907
   
First Author: Lau AN
Year: 2020
Journal: Elife
Title: Dissecting cell-type-specific metabolism in pancreatic ductal adenocarcinoma.
Volume: 9
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Publication
29596465 | J:261064
First Author: Germino EA
Year: 2018
Journal: PLoS One
Title: Homozygous KSR1 deletion attenuates morbidity but does not prevent tumor development in a mouse model of RAS-driven pancreatic cancer.
Volume: 13
Issue: 3
Pages: e0194998
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Publication
24856585 | J:213505
First Author: Rhim AD
Year: 2014
Journal: Cancer Cell
Title: Stromal elements act to restrain, rather than support, pancreatic ductal adenocarcinoma.
Volume: 25
Issue: 6
Pages: 735-47
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Publication
22698406 | J:189283
First Author: Bayne LJ
Year: 2012
Journal: Cancer Cell
Title: Tumor-derived granulocyte-macrophage colony-stimulating factor regulates myeloid inflammation and T cell immunity in pancreatic cancer.
Volume: 21
Issue: 6
Pages: 822-35
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Publication
22265420 | J:181291
First Author: Rhim AD
Year: 2012
Journal: Cell
Title: EMT and dissemination precede pancreatic tumor formation.
Volume: 148
Issue: 1-2
Pages: 349-61
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Publication
23284900 | J:195622
First Author: Avila JL
Year: 2012
Journal: PLoS One
Title: Notch1 is not required for acinar-to-ductal metaplasia in a model of Kras-induced pancreatic ductal adenocarcinoma.
Volume: 7
Issue: 12
Pages: e52133
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Publication
22439937 | J:189345
First Author: Provenzano PP
Year: 2012
Journal: Cancer Cell
Title: Enzymatic targeting of the stroma ablates physical barriers to treatment of pancreatic ductal adenocarcinoma.
Volume: 21
Issue: 3
Pages: 418-29
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Publication
23384121 | J:196611
First Author: van Asselt SJ
Year: 2013
Journal: Cilia
Title: Pancreatic cyst development: insights from von Hippel-Lindau disease.
Volume: 2
Issue: 1
Pages: 3
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Publication
23977255 | J:206428
First Author: Puri S
Year: 2013
Journal: PLoS One
Title: Elimination of von Hippel-Lindau function perturbs pancreas endocrine homeostasis in mice.
Volume: 8
Issue: 8
Pages: e72213
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Publication
19065050 | J:144713
First Author: Cantley J
Year: 2009
Journal: J Clin Invest
Title: Deletion of the von Hippel-Lindau gene in pancreatic beta cells impairs glucose homeostasis in mice.
Volume: 119
Issue: 1
Pages: 125-35
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Publication
11857783 | J:75140
First Author: Yang X
Year: 2002
Journal: Genesis
Title: Generation of Smad4/Dpc4 conditional knockout mice.
Volume: 32
Issue: 2
Pages: 80-1
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Publication
30515799 | J:320879
First Author: Amit M
Year: 2019
Journal: Int J Cancer
Title: RET, a targetable driver of pancreatic adenocarcinoma.
Volume: 144
Issue: 12
Pages: 3014-3022
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Publication
37216093 | J:338920
First Author: Fadzeyeva E
Year: 2023
Journal: iScience
Title: Pancreas-derived DPP4 is not essential for glucose homeostasis under metabolic stress.
Volume: 26
Issue: 5
Pages: 106748
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Publication
22784710 | J:208743
First Author: Hill R
Year: 2012
Journal: Mol Cancer Ther
Title: Cell intrinsic role of COX-2 in pancreatic cancer development.
Volume: 11
Issue: 10
Pages: 2127-37
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Publication
28125909 | J:349084
First Author: Chen M
Year: 2017
Journal: Hum Gene Ther Methods
Title: Efficient Gene Delivery and Expression in Pancreas and Pancreatic Tumors by Capsid-Optimized AAV8 Vectors.
Volume: 28
Issue: 1
Pages: 49-59
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Publication
22586351 | J:193072
First Author: Chiao PJ
Year: 2011
Journal: Cancer Discov
Title: Kras, Pten, NF-κB, and inflammation: dangerous liaisons.
Volume: 1
Issue: 2
Pages: 103-5
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Publication
36256464 | J:332123
 
First Author: Dixit A
Year: 2022
Journal: JCI Insight
Title: Targeting TNF-α-producing macrophages activates antitumor immunity in pancreatic cancer via IL-33 signaling.
Volume: 7
Issue: 22
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Publication
30185628 | J:266839
First Author: Renz BW
Year: 2018
Journal: Cancer Discov
Title: Cholinergic Signaling via Muscarinic Receptors Directly and Indirectly Suppresses Pancreatic Tumorigenesis and Cancer Stemness.
Volume: 8
Issue: 11
Pages: 1458-1473
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Publication
27150016 | J:234486
First Author: Amit M
Year: 2016
Journal: Nat Rev Cancer
Title: Mechanisms of cancer dissemination along nerves.
Volume: 16
Issue: 6
Pages: 399-408
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Publication
19147554 | J:143713
First Author: Seeley ES
Year: 2009
Journal: Cancer Res
Title: Pancreatic cancer and precursor pancreatic intraepithelial neoplasia lesions are devoid of primary cilia.
Volume: 69
Issue: 2
Pages: 422-30
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Publication
22140463 | J:181133
First Author: Carrière C
Year: 2011
Journal: PLoS One
Title: Acute pancreatitis accelerates initiation and progression to pancreatic cancer in mice expressing oncogenic Kras in the nestin cell lineage.
Volume: 6
Issue: 11
Pages: e27725
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Publication
18615728 | J:138548
First Author: An W
Year: 2008
Journal: Genesis
Title: Conditional activation of a single-copy L1 transgene in mice by Cre.
Volume: 46
Issue: 7
Pages: 373-83
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Publication
26825527 | J:232633
First Author: Mir-Coll J
Year: 2016
Journal: Diabetologia
Title: Genetic models rule out a major role of beta cell glycogen in the control of glucose homeostasis.
Volume: 59
Issue: 5
Pages: 1012-20
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Publication
27813676 | J:245502
First Author: Yang Y
Year: 2017
Journal: Endocrinology
Title: Differential Gene Dosage Effects of Diabetes-Associated Gene GLIS3 in Pancreatic β Cell Differentiation and Function.
Volume: 158
Issue: 1
Pages: 9-20
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Publication
19340311 | J:148174
First Author: Shen HC
Year: 2009
Journal: PLoS One
Title: Deciphering von Hippel-Lindau (VHL/Vhl)-associated pancreatic manifestations by inactivating Vhl in specific pancreatic cell populations.
Volume: 4
Issue: 4
Pages: e4897
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Publication
22160727 | J:180138
First Author: Frost RJ
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Control of glucose homeostasis and insulin sensitivity by the Let-7 family of microRNAs.
Volume: 108
Issue: 52
Pages: 21075-80
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Publication
27197190 | J:232784
First Author: Yang S
Year: 2016
Journal: Cancer Res
Title: A Novel MIF Signaling Pathway Drives the Malignant Character of Pancreatic Cancer by Targeting NR3C2.
Volume: 76
Issue: 13
Pages: 3838-50
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Publication
20881124 | J:164878
First Author: Chen G
Year: 2010
Journal: J Neurosci
Title: CREB binding protein is required for both short-term and long-term memory formation.
Volume: 30
Issue: 39
Pages: 13066-77
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Publication
19665969 | J:153905
First Author: Collombat P
Year: 2009
Journal: Cell
Title: The ectopic expression of Pax4 in the mouse pancreas converts progenitor cells into alpha and subsequently beta cells.
Volume: 138
Issue: 3
Pages: 449-62
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Publication
19028876 | J:142188
First Author: De La O JP
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Notch and Kras reprogram pancreatic acinar cells to ductal intraepithelial neoplasia.
Volume: 105
Issue: 48
Pages: 18907-12
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14657333 | J:86975
First Author: Murtaugh LC
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Notch signaling controls multiple steps of pancreatic differentiation.
Volume: 100
Issue: 25
Pages: 14920-5
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31877165 | J:283370
First Author: Park D
Year: 2019
Journal: PLoS One
Title: Murine models for familial pancreatic cancer: Histopathology, latency and drug sensitivity among cancers of Palb2, Brca1 and Brca2 mutant mouse strains.
Volume: 14
Issue: 12
Pages: e0226714
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Publication
25043018 | J:217116
First Author: Walz S
Year: 2014
Journal: Nature
Title: Activation and repression by oncogenic MYC shape tumour-specific gene expression profiles.
Volume: 511
Issue: 7510
Pages: 483-7
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Publication
23226501 | J:195686
First Author: Collins MA
Year: 2012
Journal: PLoS One
Title: Metastatic pancreatic cancer is dependent on oncogenic Kras in mice.
Volume: 7
Issue: 12
Pages: e49707
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Publication
33782087 | J:305076
 
First Author: Kemp SB
Year: 2021
Journal: Life Sci Alliance
Title: Pancreatic cancer is marked by complement-high blood monocytes and tumor-associated macrophages.
Volume: 4
Issue: 6
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Publication
24717934 | J:310016
First Author: Morran DC
Year: 2014
Journal: Gut
Title: Targeting mTOR dependency in pancreatic cancer.
Volume: 63
Issue: 9
Pages: 1481-9
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Publication
34249932 | J:308024
 
First Author: Urrutia G
Year: 2021
Journal: Front Cell Dev Biol
Title: Inactivation of the Euchromatic Histone-Lysine N-Methyltransferase 2 Pathway in Pancreatic Epithelial Cells Antagonizes Cancer Initiation and Pancreatitis-Associated Promotion by Altering Growth and Immune Gene Expression Networks.
Volume: 9
Pages: 681153
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Publication
19808022 | J:153660
First Author: Granot Z
Year: 2009
Journal: Cell Metab
Title: LKB1 regulates pancreatic beta cell size, polarity, and function.
Volume: 10
Issue: 4
Pages: 296-308
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17141632 | J:144661
First Author: Zhang W
Year: 2006
Journal: Cell Metab
Title: PERK EIF2AK3 control of pancreatic beta cell differentiation and proliferation is required for postnatal glucose homeostasis.
Volume: 4
Issue: 6
Pages: 491-7
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Publication
22052106 | J:320501
First Author: DiNorcia J
Year: 2012
Journal: J Gastrointest Surg
Title: RAGE gene deletion inhibits the development and progression of ductal neoplasia and prolongs survival in a murine model of pancreatic cancer.
Volume: 16
Issue: 1
Pages: 104-12; discussion 112
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19246386 | J:146777
First Author: Tian H
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Hedgehog signaling is restricted to the stromal compartment during pancreatic carcinogenesis.
Volume: 106
Issue: 11
Pages: 4254-9
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Publication
23788637 | J:203472
First Author: Gupta D
Year: 2013
Journal: J Biol Chem
Title: Peroxisome proliferator-activated receptor γ (PPARγ) and its target genes are downstream effectors of FoxO1 protein in islet β-cells: mechanism of β-cell compensation and failure.
Volume: 288
Issue: 35
Pages: 25440-9
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27089513 | J:235172
First Author: Laklai H
Year: 2016
Journal: Nat Med
Title: Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression.
Volume: 22
Issue: 5
Pages: 497-505
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Publication
35316682 | J:322171
 
First Author: Yang J
Year: 2022
Journal: EBioMedicine
Title: Dynamic profiling of immune microenvironment during pancreatic cancer development suggests early intervention and combination strategy of immunotherapy.
Volume: 78
Pages: 103958
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28971839 | J:270385
First Author: Hamada S
Year: 2018
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Simultaneous K-ras activation and Keap1 deletion cause atrophy of pancreatic parenchyma.
Volume: 314
Issue: 1
Pages: G65-G74
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33668735 | J:317984
 
First Author: Liu TW
Year: 2021
Journal: Cells
Title: Multi-Modal Multi-Spectral Intravital Macroscopic Imaging of Signaling Dynamics in Real Time during Tumor-Immune Interactions.
Volume: 10
Issue: 3
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23034633 | J:189073
First Author: Bénazet JD
Year: 2012
Journal: Development
Title: Smad4 is required to induce digit ray primordia and to initiate the aggregation and differentiation of chondrogenic progenitors in mouse limb buds.
Volume: 139
Issue: 22
Pages: 4250-60
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17123526 | J:124951
First Author: Cano DA
Year: 2006
Journal: Gastroenterology
Title: Primary cilia deletion in pancreatic epithelial cells results in cyst formation and pancreatitis.
Volume: 131
Issue: 6
Pages: 1856-69
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10804174 | J:78865
First Author: Herrera PL
Year: 2000
Journal: Development
Title: Adult insulin- and glucagon-producing cells differentiate from two independent cell lineages.
Volume: 127
Issue: 11
Pages: 2317-22
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23563314 | J:201459
First Author: Li N
Year: 2013
Journal: J Clin Invest
Title: Loss of acinar cell IKKα triggers spontaneous pancreatitis in mice.
Volume: 123
Issue: 5
Pages: 2231-43
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Publication
35472764 | J:326794
First Author: Georgiadou E
Year: 2022
Journal: Diabetes
Title: Mitofusins Mfn1 and Mfn2 Are Required to Preserve Glucose- but Not Incretin-Stimulated β-Cell Connectivity and Insulin Secretion.
Volume: 71
Issue: 7
Pages: 1472-1489
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24788257 | J:216102
First Author: Morris JP 4th
Year: 2014
Journal: PLoS One
Title: Dicer regulates differentiation and viability during mouse pancreatic cancer initiation.
Volume: 9
Issue: 5
Pages: e95486
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Publication
27697926 | J:306995
First Author: Kunii M
Year: 2016
Journal: J Cell Biol
Title: Opposing roles for SNAP23 in secretion in exocrine and endocrine pancreatic cells.
Volume: 215
Issue: 1
Pages: 121-138
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Publication
29310936 | J:274102
 
First Author: Naumann H
Year: 2018
Journal: Mol Metab
Title: The RhoGAP Stard13 controls insulin secretion through F-actin remodeling.
Volume: 8
Pages: 96-105
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Publication
31848151 | J:285346
First Author: Kim H
Year: 2020
Journal: Diabetes
Title: PRMT1 Is Required for the Maintenance of Mature β-Cell Identity.
Volume: 69
Issue: 3
Pages: 355-368
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Publication
32554750 | J:296297
First Author: Zhao Y
Year: 2020
Journal: Cancer Res
Title: Oncogene-Induced Senescence Limits the Progression of Pancreatic Neoplasia through Production of Activin A.
Volume: 80
Issue: 16
Pages: 3359-3371
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Publication
30355799 | J:266568
 
First Author: Zhou L
Year: 2018
Journal: Sci Transl Med
Title: Suppression of stromal-derived Dickkopf-3 (DKK3) inhibits tumor progression and prolongs survival in pancreatic ductal adenocarcinoma.
Volume: 10
Issue: 464
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Publication
31197017 | J:278164
First Author: Elyada E
Year: 2019
Journal: Cancer Discov
Title: Cross-Species Single-Cell Analysis of Pancreatic Ductal Adenocarcinoma Reveals Antigen-Presenting Cancer-Associated Fibroblasts.
Volume: 9
Issue: 8
Pages: 1102-1123
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Publication
26525103 | J:226758
First Author: Stromnes IM
Year: 2015
Journal: Cancer Cell
Title: T Cells Engineered against a Native Antigen Can Surmount Immunologic and Physical Barriers to Treat Pancreatic Ductal Adenocarcinoma.
Volume: 28
Issue: 5
Pages: 638-652
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Publication
32339496 | J:293219
First Author: Ruggeri JM
Year: 2020
Journal: Am J Pathol
Title: Discoidin Domain Receptor 1 (DDR1) Is Necessary for Tissue Homeostasis in Pancreatic Injury and Pathogenesis of Pancreatic Ductal Adenocarcinoma.
Volume: 190
Issue: 8
Pages: 1735-1751
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Publication
20616010 | J:162410
First Author: Wong WP
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Extranuclear estrogen receptor-alpha stimulates NeuroD1 binding to the insulin promoter and favors insulin synthesis.
Volume: 107
Issue: 29
Pages: 13057-62
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Publication
38237591 | J:346123
First Author: Darrigrand JF
Year: 2024
Journal: Dev Cell
Title: Acinar-ductal cell rearrangement drives branching morphogenesis of the murine pancreas in an IGF/PI3K-dependent manner.
Volume: 59
Issue: 3
Pages: 326-338.e5
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Publication
33941611 | J:307153
First Author: Schoeps B
Year: 2021
Journal: Cancer Res
Title: TIMP1 Triggers Neutrophil Extracellular Trap Formation in Pancreatic Cancer.
Volume: 81
Issue: 13
Pages: 3568-3579
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Publication
23042302 | J:193646
First Author: Tran K
Year: 2013
Journal: Carcinogenesis
Title: The combination of the histone deacetylase inhibitor vorinostat and synthetic triterpenoids reduces tumorigenesis in mouse models of cancer.
Volume: 34
Issue: 1
Pages: 199-210
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Publication
23749641 | J:199648
First Author: Nobis M
Year: 2013
Journal: Cancer Res
Title: Intravital FLIM-FRET imaging reveals dasatinib-induced spatial control of src in pancreatic cancer.
Volume: 73
Issue: 15
Pages: 4674-86
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Publication
34533565 | J:324225
 
First Author: Hermann CD
Year: 2021
Journal: J Exp Med
Title: TIMP1 expression underlies sex disparity in liver metastasis and survival in pancreatic cancer.
Volume: 218
Issue: 11
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Publication
36209169 | J:333480
First Author: Li J
Year: 2023
Journal: Cell Death Differ
Title: Sirtuin 4 activates autophagy and inhibits tumorigenesis by upregulating the p53 signaling pathway.
Volume: 30
Issue: 2
Pages: 313-326
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Publication
17114586 | J:116111
First Author: Pasca di Magliano M
Year: 2006
Journal: Genes Dev
Title: Hedgehog/Ras interactions regulate early stages of pancreatic cancer.
Volume: 20
Issue: 22
Pages: 3161-73
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Publication
38110836 | J:357563
First Author: Xu J
Year: 2024
Journal: Adv Sci (Weinh)
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