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Search results 1101 to 1200 out of 2663 for Psen1

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Category: Publication
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Type Details Score
Publication
15613480 | J:97070
First Author: Wood DR
Year: 2005
Journal: J Biol Chem
Title: Intracellular retention of caveolin 1 in presenilin-deficient cells.
Volume: 280
Issue: 8
Pages: 6663-8
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Publication
21195117 | J:170558
First Author: Hoeing K
Year: 2011
Journal: Biochim Biophys Acta
Title: Presenilin-1 processing of ErbB4 in fetal type II cells is necessary for control of fetal lung maturation.
Volume: 1813
Issue: 3
Pages: 480-91
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Publication
23103503 | J:206556
 
First Author: Neely Kayala KM
Year: 2012
Journal: Brain Res
Title: Presenilin-null cells have altered two-pore calcium channel expression and lysosomal calcium: implications for lysosomal function.
Volume: 1489
Pages: 8-16
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Publication
24462774 | J:210843
First Author: Fiaturi N
Year: 2014
Journal: Biochim Biophys Acta
Title: Dissociated presenilin-1 and TACE processing of ErbB4 in lung alveolar type II cell differentiation.
Volume: 1843
Issue: 4
Pages: 797-805
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Publication
24844149 | J:214313
 
First Author: Albers S
Year: 2014
Journal: Neurobiol Dis
Title: Nuclear 82-kDa choline acetyltransferase decreases amyloidogenic APP metabolism in neurons from APP/PS1 transgenic mice.
Volume: 69
Pages: 32-42
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Publication
33087587 | J:325261
First Author: Li J
Year: 2020
Journal: Aging (Albany NY)
Title: MicroRNA-338-5p alleviates neuronal apoptosis via directly targeting BCL2L11 in APP/PS1 mice.
Volume: 12
Issue: 20
Pages: 20728-20742
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Publication
36456828 | J:332318
First Author: Kwak M
Year: 2022
Journal: Nat Cell Biol
Title: Adherens junctions organize size-selective proteolytic hotspots critical for Notch signalling.
Volume: 24
Issue: 12
Pages: 1739-1753
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Publication
10854253 | J:79164
First Author: Kashiwa A
Year: 2000
Journal: J Neurochem
Title: Isolation and characterization of novel presenilin binding protein.
Volume: 75
Issue: 1
Pages: 109-16
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Publication
15634781 | J:95769
First Author: Ma G
Year: 2005
Journal: J Neurosci
Title: APH-1a is the principal mammalian APH-1 isoform present in gamma-secretase complexes during embryonic development.
Volume: 25
Issue: 1
Pages: 192-8
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Publication
10421573 | J:95663
First Author: Hartmann D
Year: 1999
Journal: Curr Biol
Title: Presenilin-1 deficiency leads to loss of Cajal-Retzius neurons and cortical dysplasia similar to human type 2 lissencephaly.
Volume: 9
Issue: 14
Pages: 719-27
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Publication
11953314 | J:115561
First Author: Marambaud P
Year: 2002
Journal: EMBO J
Title: A presenilin-1/gamma-secretase cleavage releases the E-cadherin intracellular domain and regulates disassembly of adherens junctions.
Volume: 21
Issue: 8
Pages: 1948-56
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Publication
30429473 | J:268351
First Author: Barthet G
Year: 2018
Journal: Nat Commun
Title: Presenilin-mediated cleavage of APP regulates synaptotagmin-7 and presynaptic plasticity.
Volume: 9
Issue: 1
Pages: 4780
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Publication
8632996 | J:35032
First Author: Amson RB
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: Isolation of 10 differentially expressed cDNAs in p53-induced apoptosis: activation of the vertebrate homologue of the drosophila seven in absentia gene.
Volume: 93
Issue: 9
Pages: 3953-7
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Publication
17698590 | J:126088
First Author: Laky K
Year: 2007
Journal: J Exp Med
Title: Presenilins regulate alphabeta T cell development by modulating TCR signaling.
Volume: 204
Issue: 9
Pages: 2115-29
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Publication
29577585 | J:261918
First Author: Zhang Y
Year: 2018
Journal: Aging Cell
Title: nNOS-CAPON interaction mediates amyloid-β-induced neurotoxicity, especially in the early stages.
Volume: 17
Issue: 3
Pages: e12754
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Publication
15866159 | J:98438
First Author: Huppert SS
Year: 2005
Journal: Dev Cell
Title: Analysis of Notch function in presomitic mesoderm suggests a gamma-secretase-independent role for presenilins in somite differentiation.
Volume: 8
Issue: 5
Pages: 677-88
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Publication
19118188 | J:239203
First Author: Puzzo D
Year: 2008
Journal: J Neurosci
Title: Picomolar amyloid-beta positively modulates synaptic plasticity and memory in hippocampus.
Volume: 28
Issue: 53
Pages: 14537-45
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Publication
15452145 | J:93423
First Author: Esselens C
Year: 2004
Journal: J Cell Biol
Title: Presenilin 1 mediates the turnover of telencephalin in hippocampal neurons via an autophagic degradative pathway.
Volume: 166
Issue: 7
Pages: 1041-54
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Publication
17222949 | J:137701
First Author: Zhang H
Year: 2008
Journal: Neurobiol Aging
Title: Presenilins regulate the cellular level of the tumor suppressor PTEN.
Volume: 29
Issue: 5
Pages: 653-60
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Publication
17920016 | J:126954
First Author: Liu Q
Year: 2007
Journal: Neuron
Title: Amyloid precursor protein regulates brain apolipoprotein E and cholesterol metabolism through lipoprotein receptor LRP1.
Volume: 56
Issue: 1
Pages: 66-78
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Publication
27349870 | J:238594
First Author: Biswas S
Year: 2016
Journal: Biochem Biophys Res Commun
Title: Posttranslational proteolytic processing of Leda-1/Pianp involves cleavage by MMPs, ADAM10/17 and gamma-secretase.
Volume: 477
Issue: 4
Pages: 661-666
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Publication
20130175 | J:157933
First Author: Zhao G
Year: 2010
Journal: J Neurosci
Title: Gamma-secretase composed of PS1/Pen2/Aph1a can cleave notch and amyloid precursor protein in the absence of nicastrin.
Volume: 30
Issue: 5
Pages: 1648-56
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Publication
15474363 | J:93093
First Author: Hébert SS
Year: 2004
Journal: Neurobiol Dis
Title: Coordinated and widespread expression of gamma-secretase in vivo: evidence for size and molecular heterogeneity.
Volume: 17
Issue: 2
Pages: 260-72
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Publication
19573812 | J:150340
First Author: Demehri S
Year: 2009
Journal: Cancer Cell
Title: Epidermal Notch1 loss promotes skin tumorigenesis by impacting the stromal microenvironment.
Volume: 16
Issue: 1
Pages: 55-66
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Publication
20208556 | J:168265
First Author: Rocher-Ros V
Year: 2010
Journal: Oncogene
Title: Presenilin modulates EGFR signaling and cell transformation by regulating the ubiquitin ligase Fbw7.
Volume: 29
Issue: 20
Pages: 2950-61
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Publication
23918386 | J:200916
First Author: Wu B
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Presenilins regulate calcium homeostasis and presynaptic function via ryanodine receptors in hippocampal neurons.
Volume: 110
Issue: 37
Pages: 15091-6
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Publication
22897852 | J:191822
First Author: Maraver A
Year: 2012
Journal: Cancer Cell
Title: Therapeutic effect of γ-secretase inhibition in KrasG12V-driven non-small cell lung carcinoma by derepression of DUSP1 and inhibition of ERK.
Volume: 22
Issue: 2
Pages: 222-34
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Publication
15066262 | J:89760
First Author: Saura CA
Year: 2004
Journal: Neuron
Title: Loss of presenilin function causes impairments of memory and synaptic plasticity followed by age-dependent neurodegeneration.
Volume: 42
Issue: 1
Pages: 23-36
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Publication
23274884 | J:199052
First Author: Niedowicz DM
Year: 2013
Journal: Biochim Biophys Acta
Title: Leptin regulates amyloid β production via the γ-secretase complex.
Volume: 1832
Issue: 3
Pages: 439-44
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Publication
12391611 | J:91975
First Author: Yuasa S
Year: 2002
Journal: J Neurosci Res
Title: Impaired cell cycle control of neuronal precursor cells in the neocortical primordium of presenilin-1-deficient mice.
Volume: 70
Issue: 3
Pages: 501-13
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Publication
30189209 | J:269833
First Author: Eftekharzadeh B
Year: 2018
Journal: Neuron
Title: Tau Protein Disrupts Nucleocytoplasmic Transport in Alzheimer's Disease.
Volume: 99
Issue: 5
Pages: 925-940.e7
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Publication
27391799 | J:259360
First Author: Yi C
Year: 2016
Journal: Cell Death Differ
Title: Astroglial connexin43 contributes to neuronal suffering in a mouse model of Alzheimer's disease.
Volume: 23
Issue: 10
Pages: 1691-701
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Publication
31943063 | J:292748
First Author: Li L
Year: 2020
Journal: Hum Mol Genet
Title: Reduction of Tet2 exacerbates early stage Alzheimer's pathology and cognitive impairments in 2×Tg-AD mice.
Volume: 29
Issue: 11
Pages: 1833-1852
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Publication
32033586 | J:304172
First Author: Fan C
Year: 2020
Journal: Mol Autism
Title: Transcriptomics of Gabra4 knockout mice reveals common NMDAR pathways underlying autism, memory, and epilepsy.
Volume: 11
Issue: 1
Pages: 13
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Publication
15896720 | J:98599
First Author: Kim MY
Year: 2005
Journal: Biochem Biophys Res Commun
Title: Presenilin acts as a positive regulator of basal level activity of ERK through the Raf-MEK1 signaling pathway.
Volume: 332
Issue: 2
Pages: 609-13
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Publication
11943765 | J:76858
First Author: Leem JY
Year: 2002
Journal: J Biol Chem
Title: Presenilin 1 is required for maturation and cell surface accumulation of nicastrin.
Volume: 277
Issue: 21
Pages: 19236-40
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Publication
16511561 | J:106994
First Author: Georgakopoulos A
Year: 2006
Journal: EMBO J
Title: Metalloproteinase/Presenilin1 processing of ephrinB regulates EphB-induced Src phosphorylation and signaling.
Volume: 25
Issue: 6
Pages: 1242-52
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Publication
21597003 | J:177000
First Author: Barthet G
Year: 2011
Journal: FASEB J
Title: Inhibitors of γ-secretase stabilize the complex and differentially affect processing of amyloid precursor protein and other substrates.
Volume: 25
Issue: 9
Pages: 2937-46
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Publication
16641999 | J:108398
First Author: Chen F
Year: 2006
Journal: Nature
Title: TMP21 is a presenilin complex component that modulates gamma-secretase but not epsilon-secretase activity.
Volume: 440
Issue: 7088
Pages: 1208-12
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Publication
19457123 | J:150744
First Author: Sevalle J
Year: 2009
Journal: J Neurochem
Title: Pharmacological evidences for DFK167-sensitive presenilin-independent gamma-secretase-like activity.
Volume: 110
Issue: 1
Pages: 275-83
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Publication
11104755 | J:67950
First Author: Kirschenbaum F
Year: 2001
Journal: J Biol Chem
Title: Substitution of a glycogen synthase kinase-3beta phosphorylation site in presenilin 1 separates presenilin function from beta-catenin signaling.
Volume: 276
Issue: 10
Pages: 7366-75
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Publication
23585889 | J:206895
First Author: Stemmer N
Year: 2013
Journal: PLoS One
Title: Generation of amyloid-β is reduced by the interaction of calreticulin with amyloid precursor protein, presenilin and nicastrin.
Volume: 8
Issue: 4
Pages: e61299
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34646371 | J:322379
First Author: Huang L
Year: 2021
Journal: Theranostics
Title: Upregulated NMDAR-mediated GABAergic transmission underlies autistic-like deficits in Htr3a knockout mice.
Volume: 11
Issue: 19
Pages: 9296-9310
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15274632 | J:320147
First Author: Fraering PC
Year: 2004
Journal: Biochemistry
Title: Purification and characterization of the human gamma-secretase complex.
Volume: 43
Issue: 30
Pages: 9774-89
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8533168 | J:42424
First Author: Pericak-Vance MA
Year: 1995
Journal: Trends Genet
Title: Genetic susceptibility to Alzheimer disease.
Volume: 11
Issue: 12
Pages: 504-8
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9928488 | J:52884
 
First Author: Price DL
Year: 1998
Journal: Annu Rev Genet
Title: Alzheimer's disease: genetic studies and transgenic models.
Volume: 32
Pages: 461-93
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14515137 | J:85858
First Author: Mirnics ZK
Year: 2003
Journal: Mol Psychiatry
Title: DNA microarray profiling of developing PS1-deficient mouse brain reveals complex and coregulated expression changes.
Volume: 8
Issue: 10
Pages: 863-78
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Publication
14717705 | J:97674
First Author: Culvenor JG
Year: 2004
Journal: Eur J Biochem
Title: Characterization of presenilin complexes from mouse and human brain using Blue Native gel electrophoresis reveals high expression in embryonic brain and minimal change in complex mobility with pathogenic presenilin mutations.
Volume: 271
Issue: 2
Pages: 375-85
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Publication
18456655 | J:138527
First Author: Vetrivel KS
Year: 2008
Journal: J Biol Chem
Title: Evidence that CD147 modulation of beta-amyloid (Abeta) levels is mediated by extracellular degradation of secreted Abeta.
Volume: 283
Issue: 28
Pages: 19489-98
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Publication
18591429 | J:138593
First Author: Green KN
Year: 2008
Journal: J Cell Biol
Title: SERCA pump activity is physiologically regulated by presenilin and regulates amyloid beta production.
Volume: 181
Issue: 7
Pages: 1107-16
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19111578 | J:153382
First Author: Bojarski L
Year: 2009
Journal: Biochim Biophys Acta
Title: Presenilin-dependent expression of STIM proteins and dysregulation of capacitative Ca2+ entry in familial Alzheimer's disease.
Volume: 1793
Issue: 6
Pages: 1050-7
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23504710 | J:199954
First Author: Sachse CC
Year: 2013
Journal: FASEB J
Title: BACE1 and presenilin/γ-secretase regulate proteolytic processing of KCNE1 and 2, auxiliary subunits of voltage-gated potassium channels.
Volume: 27
Issue: 6
Pages: 2458-67
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Publication
10932180 | J:78989
First Author: Takahashi Y
Year: 2000
Journal: Nat Genet
Title: Mesp2 initiates somite segmentation through the Notch signalling pathway.
Volume: 25
Issue: 4
Pages: 390-6
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12834865 | J:84418
First Author: Nakajima M
Year: 2003
Journal: Mech Dev
Title: Abnormal blood vessel development in mice lacking presenilin-1.
Volume: 120
Issue: 6
Pages: 657-67
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10206645 | J:54336
First Author: De Strooper B
Year: 1999
Journal: Nature
Title: A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain.
Volume: 398
Issue: 6727
Pages: 518-22
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18507503 | J:139386
First Author: Demehri S
Year: 2008
Journal: PLoS Biol
Title: Notch-deficient skin induces a lethal systemic B-lymphoproliferative disorder by secreting TSLP, a sentinel for epidermal integrity.
Volume: 6
Issue: 5
Pages: e123
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10381505 | J:56240
First Author: Lichanska AM
Year: 1999
Journal: Blood
Title: Differentiation of the mononuclear phagocyte system during mouse embryogenesis: the role of transcription factor PU.1.
Volume: 94
Issue: 1
Pages: 127-38
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9153393 | J:40308
First Author: Wong PC
Year: 1997
Journal: Nature
Title: Presenilin 1 is required for Notch1 and DII1 expression in the paraxial mesoderm.
Volume: 387
Issue: 6630
Pages: 288-92
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10557208 | J:58465
First Author: Donoviel DB
Year: 1999
Journal: Genes Dev
Title: Mice lacking both presenilin genes exhibit early embryonic patterning defects.
Volume: 13
Issue: 21
Pages: 2801-10
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15944124 | J:100260
First Author: Pardossi-Piquard R
Year: 2005
Journal: Neuron
Title: Presenilin-dependent transcriptional control of the Abeta-degrading enzyme neprilysin by intracellular domains of betaAPP and APLP.
Volume: 46
Issue: 4
Pages: 541-54
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15886206 | J:100835
First Author: Vetrivel KS
Year: 2005
Journal: J Biol Chem
Title: Spatial segregation of gamma-secretase and substrates in distinct membrane domains.
Volume: 280
Issue: 27
Pages: 25892-900
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16169548 | J:103603
First Author: Pan Y
Year: 2005
Journal: Dev Biol
Title: Notch1 and 2 cooperate in limb ectoderm to receive an early Jagged2 signal regulating interdigital apoptosis.
Volume: 286
Issue: 2
Pages: 472-82
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Publication
23774650 | J:310933
 
First Author: Rutherford NJ
Year: 2013
Journal: Brain Res
Title: Unbiased screen reveals ubiquilin-1 and -2 highly associated with huntingtin inclusions.
Volume: 1524
Pages: 62-73
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11567612 | J:71606
First Author: Yu H
Year: 2001
Journal: Neuron
Title: APP processing and synaptic plasticity in presenilin-1 conditional knockout mice.
Volume: 31
Issue: 5
Pages: 713-26
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Publication
20541250 | J:165993
First Author: Lee JH
Year: 2010
Journal: Cell
Title: Lysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutations.
Volume: 141
Issue: 7
Pages: 1146-58
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Publication
24715457 | J:208850
First Author: Hatakeyama J
Year: 2014
Journal: Development
Title: Cadherin-based adhesions in the apical endfoot are required for active Notch signaling to control neurogenesis in vertebrates.
Volume: 141
Issue: 8
Pages: 1671-82
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17360776 | J:123846
First Author: Morimoto M
Year: 2007
Journal: Development
Title: The negative regulation of Mesp2 by mouse Ripply2 is required to establish the rostro-caudal patterning within a somite.
Volume: 134
Issue: 8
Pages: 1561-9
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17306789 | J:122532
First Author: Takahashi Y
Year: 2007
Journal: Dev Biol
Title: Appropriate suppression of Notch signaling by Mesp factors is essential for stripe pattern formation leading to segment boundary formation.
Volume: 304
Issue: 2
Pages: 593-603
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11937492 | J:75878
First Author: Hitoshi S
Year: 2002
Journal: Genes Dev
Title: Notch pathway molecules are essential for the maintenance, but not the generation, of mammalian neural stem cells.
Volume: 16
Issue: 7
Pages: 846-58
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19779553 | J:154114
First Author: Ferjentsik Z
Year: 2009
Journal: PLoS Genet
Title: Notch is a critical component of the mouse somitogenesis oscillator and is essential for the formation of the somites.
Volume: 5
Issue: 9
Pages: e1000662
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Publication
19723764 | J:152074
First Author: Cras-Méneur C
Year: 2009
Journal: Genes Dev
Title: Presenilins, Notch dose control the fate of pancreatic endocrine progenitors during a narrow developmental window.
Volume: 23
Issue: 17
Pages: 2088-101
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34107249 | J:306630
First Author: Zhang T
Year: 2021
Journal: Cell Rep
Title: Generation of excitatory and inhibitory neurons from common progenitors via Notch signaling in the cerebellum.
Volume: 35
Issue: 10
Pages: 109208
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15525534 | J:94517
First Author: Pan Y
Year: 2004
Journal: Dev Cell
Title: gamma-secretase functions through Notch signaling to maintain skin appendages but is not required for their patterning or initial morphogenesis.
Volume: 7
Issue: 5
Pages: 731-43
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Publication
16018997 | J:102734
First Author: Yang J
Year: 2005
Journal: Exp Cell Res
Title: The ciliary rootlet interacts with kinesin light chains and may provide a scaffold for kinesin-1 vesicular cargos.
Volume: 309
Issue: 2
Pages: 379-89
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Publication
15192701 | J:91529
First Author: Baki L
Year: 2004
Journal: EMBO J
Title: PS1 activates PI3K thus inhibiting GSK-3 activity and tau overphosphorylation: effects of FAD mutations.
Volume: 23
Issue: 13
Pages: 2586-96
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Publication
27256505 | J:236499
 
First Author: Liu L
Year: 2016
Journal: Neuroscience
Title: Neuronal expression of ILEI/FAM3C and its reduction in Alzheimer's disease.
Volume: 330
Pages: 236-46
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11440986 | J:70373
First Author: Mills M
Year: 2001
Journal: Hum Mol Genet
Title: Differential expression of the actin-binding proteins, alpha-actinin-2 and -3, in different species: implications for the evolution of functional redundancy.
Volume: 10
Issue: 13
Pages: 1335-46
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23913046 | J:208234
First Author: Satpathy AT
Year: 2013
Journal: Nat Immunol
Title: Notch2-dependent classical dendritic cells orchestrate intestinal immunity to attaching-and-effacing bacterial pathogens.
Volume: 14
Issue: 9
Pages: 937-48
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Publication
25995356 | J:239367
First Author: Stasiulewicz M
Year: 2015
Journal: Development
Title: A conserved role for Notch signaling in priming the cellular response to Shh through ciliary localisation of the key Shh transducer Smo.
Volume: 142
Issue: 13
Pages: 2291-303
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Publication
17359917 | J:132095
First Author: Peng CY
Year: 2007
Journal: Neuron
Title: Notch and MAML signaling drives Scl-dependent interneuron diversity in the spinal cord.
Volume: 53
Issue: 6
Pages: 813-27
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Publication
34990407 | J:321806
 
First Author: Dave JM
Year: 2022
Journal: J Clin Invest
Title: JAGGED1/NOTCH3 activation promotes aortic hypermuscularization and stenosis in elastin deficiency.
Volume: 132
Issue: 5
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35575074 | J:325764
 
First Author: Xia Y
Year: 2022
Journal: Development
Title: Presenilin enhancer 2 is crucial for the transition of apical progenitors into neurons but into not basal progenitors in the developing hippocampus.
Volume: 149
Issue: 10
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Publication
28215940 | J:241013
First Author: Grassmeyer J
Year: 2017
Journal: Dev Biol
Title: Elf5 is a principal cell lineage specific transcription factor in the kidney that contributes to Aqp2 and Avpr2 gene expression.
Volume: 424
Issue: 1
Pages: 77-89
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Publication
25438880 | J:221387
First Author: Liu L
Year: 2015
Journal: J Neurochem
Title: Pre-synaptic localization of the γ-secretase-inhibiting protein p24α2 in the mammalian brain.
Volume: 133
Issue: 3
Pages: 422-31
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Publication
18694942 | J:142471
First Author: Tsao PN
Year: 2008
Journal: J Biol Chem
Title: Gamma-secretase activation of notch signaling regulates the balance of proximal and distal fates in progenitor cells of the developing lung.
Volume: 283
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