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Search results 11801 to 11900 out of 18692 for Ca1

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Category: Publication
Type Details Score
Publication
First Author: Stone S
Year: 2017
Journal: J Neurosci
Title: NF-κB Activation Protects Oligodendrocytes against Inflammation.
Volume: 37
Issue: 38
Pages: 9332-9344
Publication
First Author: Hou C
Year: 2024
Journal: Neuroreport
Title: Role of LGL1 in cerebellar primordium of embryonic mice.
Volume: 35
Issue: 6
Pages: 374-379
Publication
First Author: Arvanitis DN
Year: 2013
Journal: Development
Title: Ephrin B1 maintains apical adhesion of neural progenitors.
Volume: 140
Issue: 10
Pages: 2082-92
Publication
First Author: Cairo S
Year: 2008
Journal: Cancer Cell
Title: Hepatic stem-like phenotype and interplay of Wnt/beta-catenin and Myc signaling in aggressive childhood liver cancer.
Volume: 14
Issue: 6
Pages: 471-84
Publication
First Author: Quan YZ
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: Reprogramming by drug-like molecules leads to regeneration of cochlear hair cell-like cells in adult mice.
Volume: 120
Issue: 17
Pages: e2215253120
Publication
First Author: Oka A
Year: 2004
Journal: Genetics
Title: Hybrid breakdown caused by substitution of the X chromosome between two mouse subspecies.
Volume: 166
Issue: 2
Pages: 913-24
Publication
First Author: Sun Y
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Ghrelin stimulation of growth hormone release and appetite is mediated through the growth hormone secretagogue receptor.
Volume: 101
Issue: 13
Pages: 4679-84
Publication
First Author: Yang H
Year: 2009
Journal: J Leukoc Biol
Title: Axin expression in thymic stromal cells contributes to an age-related increase in thymic adiposity and is associated with reduced thymopoiesis independently of ghrelin signaling.
Volume: 85
Issue: 6
Pages: 928-38
Publication
First Author: Padilla-Banks E
Year: 2023
Journal: PLoS Biol
Title: Developmental estrogen exposure in mice disrupts uterine epithelial cell differentiation and causes adenocarcinoma via Wnt/β-catenin and PI3K/AKT signaling.
Volume: 21
Issue: 10
Pages: e3002334
Publication  
First Author: Kamitakahara AK
Year: 2021
Journal: Front Neurosci
Title: MET Receptor Tyrosine Kinase Regulates Lifespan Ultrasonic Vocalization and Vagal Motor Neuron Development.
Volume: 15
Pages: 768577
Publication
First Author: Zheng J
Year: 2012
Journal: J Biol Chem
Title: Conditional deletion of Notch1 and Notch2 genes in excitatory neurons of postnatal forebrain does not cause neurodegeneration or reduction of Notch mRNAs and proteins.
Volume: 287
Issue: 24
Pages: 20356-68
Publication
First Author: Radojcic V
Year: 2018
Journal: Blood
Title: Notch signaling mediated by Delta-like ligands 1 and 4 controls the pathogenesis of chronic GVHD in mice.
Volume: 132
Issue: 20
Pages: 2188-2200
Publication
First Author: LeComte MD
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Notch1-STAT3-ETBR signaling axis controls reactive astrocyte proliferation after brain injury.
Volume: 112
Issue: 28
Pages: 8726-31
Publication
First Author: Carulli AJ
Year: 2015
Journal: Dev Biol
Title: Notch receptor regulation of intestinal stem cell homeostasis and crypt regeneration.
Volume: 402
Issue: 1
Pages: 98-108
Publication
First Author: Sakamoto T
Year: 2019
Journal: Stem Cells
Title: Notch Signaling in Nestin-Expressing Cells in the Bone Marrow Maintains Erythropoiesis via Macrophage Integrity.
Volume: 37
Issue: 7
Pages: 924-936
Publication
First Author: Krass KL
Year: 2003
Journal: Neurobiol Dis
Title: Genetic loci contributing to age-related hippocampal lesions in mice.
Volume: 13
Issue: 2
Pages: 102-8
Publication
First Author: Kramerova I
Year: 2016
Journal: Hum Mol Genet
Title: Failure to up-regulate transcription of genes necessary for muscle adaptation underlies limb girdle muscular dystrophy 2A (calpainopathy).
Volume: 25
Issue: 11
Pages: 2194-2207
Publication
First Author: Hirata T
Year: 2004
Journal: Dev Dyn
Title: Zinc finger gene fez-like functions in the formation of subplate neurons and thalamocortical axons.
Volume: 230
Issue: 3
Pages: 546-56
Publication
First Author: Guyon A
Year: 2009
Journal: J Neurosci
Title: Glucose inhibition persists in hypothalamic neurons lacking tandem-pore K+ channels.
Volume: 29
Issue: 8
Pages: 2528-33
Publication
First Author: Gómez-Gonzalo M
Year: 2018
Journal: Glia
Title: Insights into the release mechanism of astrocytic glutamate evoking in neurons NMDA receptor-mediated slow depolarizing inward currents.
Volume: 66
Issue: 10
Pages: 2188-2199
Publication
First Author: Glogowska E
Year: 2021
Journal: Cell Rep
Title: Piezo1 and Piezo2 foster mechanical gating of K2P channels.
Volume: 37
Issue: 9
Pages: 110070
Publication  
First Author: Yan J
Year: 2018
Journal: J Mol Cell Cardiol
Title: The stress kinase JNK regulates gap junction Cx43 gene expression and promotes atrial fibrillation in the aged heart.
Volume: 114
Pages: 105-115
Publication
First Author: Bennett KM
Year: 2013
Journal: Am J Respir Cell Mol Biol
Title: Ephrin-B2 reverse signaling increases α5β1 integrin-mediated fibronectin deposition and reduces distal lung compliance.
Volume: 49
Issue: 4
Pages: 680-7
Publication
First Author: Grove M
Year: 2007
Journal: J Cell Biol
Title: FAK is required for axonal sorting by Schwann cells.
Volume: 176
Issue: 3
Pages: 277-82
Publication
First Author: Aber ER
Year: 2022
Journal: Cell Rep
Title: Oligodendroglial macroautophagy is essential for myelin sheath turnover to prevent neurodegeneration and death.
Volume: 41
Issue: 3
Pages: 111480
Publication
First Author: Casaletto JB
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Ezrin-mediated apical integrity is required for intestinal homeostasis.
Volume: 108
Issue: 29
Pages: 11924-9
Publication
First Author: Yan S
Year: 2019
Journal: Am J Pathol
Title: Diverse Consequences in Liver Injury in Mice with Different Autophagy Functional Status Treated with Alcohol.
Volume: 189
Issue: 9
Pages: 1744-1762
Publication
First Author: Del Real MM
Year: 2013
Journal: Development
Title: Architecture of a lymphomyeloid developmental switch controlled by PU.1, Notch and Gata3.
Volume: 140
Issue: 6
Pages: 1207-19
Publication
First Author: Akter E
Year: 2022
Journal: Cell Rep
Title: Non-degradable autophagic vacuoles are indispensable for cell competition.
Volume: 40
Issue: 9
Pages: 111292
Publication
First Author: Kruse K
Year: 2019
Journal: J Cell Biol
Title: N-cadherin signaling via Trio assembles adherens junctions to restrict endothelial permeability.
Volume: 218
Issue: 1
Pages: 299-316
Publication
First Author: Fontes MS
Year: 2014
Journal: PLoS One
Title: Changes in Cx43 and NaV1.5 expression precede the occurrence of substantial fibrosis in calcineurin-induced murine cardiac hypertrophy.
Volume: 9
Issue: 1
Pages: e87226
Publication
First Author: Miki T
Year: 2010
Journal: Mol Cancer Res
Title: The ß1-integrin-dependent function of RECK in physiologic and tumor angiogenesis.
Volume: 8
Issue: 5
Pages: 665-76
Publication
First Author: Benedito R
Year: 2005
Journal: Gene Expr Patterns
Title: Expression of Dll4 during mouse embryogenesis suggests multiple developmental roles.
Volume: 5
Issue: 6
Pages: 750-5
Publication
First Author: Scehnet JS
Year: 2007
Journal: Blood
Title: Inhibition of Dll4-mediated signaling induces proliferation of immature vessels and results in poor tissue perfusion.
Volume: 109
Issue: 11
Pages: 4753-60
Publication
First Author: Cissé M
Year: 2011
Journal: Nature
Title: Reversing EphB2 depletion rescues cognitive functions in Alzheimer model.
Volume: 469
Issue: 7328
Pages: 47-52
Publication  
First Author: Tan K
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: The Rhox gene cluster suppresses germline LINE1 transposition.
Volume: 118
Issue: 23
Publication
First Author: Wu Y
Year: 2015
Journal: Nat Cell Biol
Title: Autophagy and mTORC1 regulate the stochastic phase of somatic cell reprogramming.
Volume: 17
Issue: 6
Pages: 715-25
Publication
First Author: Zhao J
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: R-Spondin1 protects mice from chemotherapy or radiation-induced oral mucositis through the canonical Wnt/beta-catenin pathway.
Volume: 106
Issue: 7
Pages: 2331-6
Publication
First Author: Tward AD
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Distinct pathways of genomic progression to benign and malignant tumors of the liver.
Volume: 104
Issue: 37
Pages: 14771-6
Publication
First Author: Bye CR
Year: 2019
Journal: J Neurosci
Title: Axonal Growth of Midbrain Dopamine Neurons is Modulated by the Cell Adhesion Molecule ALCAM Through Trans-Heterophilic Interactions with L1cam, Chl1, and Semaphorins.
Volume: 39
Issue: 34
Pages: 6656-6667
Publication
First Author: Popova SN
Year: 2007
Journal: Mol Cell Biol
Title: Alpha11 beta1 integrin-dependent regulation of periodontal ligament function in the erupting mouse incisor.
Volume: 27
Issue: 12
Pages: 4306-16
Publication
First Author: Makhlouf A
Year: 2024
Journal: Sci Adv
Title: Integrin signaling in pluripotent cells acts as a gatekeeper of mouse germline entry.
Volume: 10
Issue: 36
Pages: eadk2252
Publication
First Author: de Anda FC
Year: 2012
Journal: Nat Neurosci
Title: Autism spectrum disorder susceptibility gene TAOK2 affects basal dendrite formation in the neocortex.
Volume: 15
Issue: 7
Pages: 1022-31
Publication
First Author: Jahn HM
Year: 2018
Journal: Sci Rep
Title: Refined protocols of tamoxifen injection for inducible DNA recombination in mouse astroglia.
Volume: 8
Issue: 1
Pages: 5913
Publication
First Author: De Obaldia ME
Year: 2013
Journal: Nat Immunol
Title: T cell development requires constraint of the myeloid regulator C/EBP-α by the Notch target and transcriptional repressor Hes1.
Volume: 14
Issue: 12
Pages: 1277-84
Publication
First Author: Bozkulak EC
Year: 2009
Journal: Mol Cell Biol
Title: Selective use of ADAM10 and ADAM17 in activation of Notch1 signaling.
Volume: 29
Issue: 21
Pages: 5679-95
Publication
First Author: Revollo L
Year: 2015
Journal: J Bone Miner Res
Title: N-cadherin restrains PTH activation of Lrp6/β-catenin signaling and osteoanabolic action.
Volume: 30
Issue: 2
Pages: 274-85
Publication
First Author: Jin S
Year: 2008
Journal: Circ Res
Title: Notch signaling regulates platelet-derived growth factor receptor-beta expression in vascular smooth muscle cells.
Volume: 102
Issue: 12
Pages: 1483-91
Publication
First Author: Hildebrand ME
Year: 2009
Journal: J Neurosci
Title: Functional coupling between mGluR1 and Cav3.1 T-type calcium channels contributes to parallel fiber-induced fast calcium signaling within Purkinje cell dendritic spines.
Volume: 29
Issue: 31
Pages: 9668-82
Publication
First Author: Le Dour C
Year: 2017
Journal: Hum Mol Genet
Title: Decreased WNT/β-catenin signalling contributes to the pathogenesis of dilated cardiomyopathy caused by mutations in the lamin a/C gene.
Volume: 26
Issue: 2
Pages: 333-343
Publication
First Author: Kanda H
Year: 2005
Journal: J Clin Invest
Title: Adipocytes from Munc18c-null mice show increased sensitivity to insulin-stimulated GLUT4 externalization.
Volume: 115
Issue: 2
Pages: 291-301
Publication
First Author: Hishiya A
Year: 2010
Journal: Circ Res
Title: BAG3 and Hsc70 interact with actin capping protein CapZ to maintain myofibrillar integrity under mechanical stress.
Volume: 107
Issue: 10
Pages: 1220-31
Publication
First Author: Salikhova A
Year: 2008
Journal: Circ Res
Title: Vascular endothelial growth factor and semaphorin induce neuropilin-1 endocytosis via separate pathways.
Volume: 103
Issue: 6
Pages: e71-9
Publication
First Author: Hulin JA
Year: 2016
Journal: Stem Cells
Title: Barx2 and Pax7 Regulate Axin2 Expression in Myoblasts by Interaction with β-Catenin and Chromatin Remodelling.
Volume: 34
Issue: 8
Pages: 2169-82
Publication
First Author: Qu C
Year: 2016
Journal: J Biol Chem
Title: Transient Expression of Fez Family Zinc Finger 2 Protein Regulates the Brn3b Gene in Developing Retinal Ganglion Cells.
Volume: 291
Issue: 14
Pages: 7661-8
Publication  
First Author: Shabanipour S
Year: 2021
Journal: Front Neurosci
Title: Upregulation of Neural Cell Adhesion Molecule 1 and Excessive Migration of Purkinje Cells in Cerebellar Cortex.
Volume: 15
Pages: 804402
Publication
First Author: van der Zee M
Year: 2013
Journal: J Pathol
Title: Alterations in Wnt-β-catenin and Pten signalling play distinct roles in endometrial cancer initiation and progression.
Volume: 230
Issue: 1
Pages: 48-58
Publication
First Author: Otero JE
Year: 2008
Journal: J Biol Chem
Title: Defective osteoclastogenesis by IKKbeta-null precursors is a result of receptor activator of NF-kappaB ligand (RANKL)-induced JNK-dependent apoptosis and impaired differentiation.
Volume: 283
Issue: 36
Pages: 24546-53
Publication
First Author: Lavado A
Year: 2014
Journal: Dev Biol
Title: Jagged1 is necessary for postnatal and adult neurogenesis in the dentate gyrus.
Volume: 388
Issue: 1
Pages: 11-21
Publication
First Author: Moreno JA
Year: 2024
Journal: Nature
Title: Emx2 underlies the development and evolution of marsupial gliding membranes.
Volume: 629
Issue: 8010
Pages: 127-135
Publication
First Author: Figeac N
Year: 2015
Journal: Cell Signal
Title: Coordinated action of Axin1 and Axin2 suppresses β-catenin to regulate muscle stem cell function.
Volume: 27
Issue: 8
Pages: 1652-65
Publication
First Author: McGee-Lawrence ME
Year: 2013
Journal: Biochem Biophys Res Commun
Title: Sclerostin deficient mice rapidly heal bone defects by activating β-catenin and increasing intramembranous ossification.
Volume: 441
Issue: 4
Pages: 886-90
Publication
First Author: Flozak AS
Year: 2010
Journal: J Biol Chem
Title: Beta-catenin/T-cell factor signaling is activated during lung injury and promotes the survival and migration of alveolar epithelial cells.
Volume: 285
Issue: 5
Pages: 3157-67
Publication
First Author: Kobayashi M
Year: 2017
Journal: Stem Cells
Title: Protein Tyrosine Phosphatase PRL2 Mediates Notch and Kit Signals in Early T Cell Progenitors.
Volume: 35
Issue: 4
Pages: 1053-1064
Publication
First Author: Bielesz B
Year: 2010
Journal: J Clin Invest
Title: Epithelial Notch signaling regulates interstitial fibrosis development in the kidneys of mice and humans.
Volume: 120
Issue: 11
Pages: 4040-54
Publication  
First Author: Bhatia S
Year: 2015
Journal: J Hematol Oncol
Title: Effects of altered ephrin-A5 and EphA4/EphA7 expression on tumor growth in a medulloblastoma mouse model.
Volume: 8
Pages: 105
Publication
First Author: Gardner SM
Year: 2005
Journal: Neuron
Title: Calcium-permeable AMPA receptor plasticity is mediated by subunit-specific interactions with PICK1 and NSF.
Volume: 45
Issue: 6
Pages: 903-15
Publication
First Author: Cadwell K
Year: 2009
Journal: Autophagy
Title: A common role for Atg16L1, Atg5 and Atg7 in small intestinal Paneth cells and Crohn disease.
Volume: 5
Issue: 2
Pages: 250-2
Publication  
First Author: Watanabe Y
Year: 2016
Journal: Nat Commun
Title: Autophagy controls centrosome number by degrading Cep63.
Volume: 7
Pages: 13508
Publication
First Author: Wei J
Year: 2016
Journal: Nat Immunol
Title: Autophagy enforces functional integrity of regulatory T cells by coupling environmental cues and metabolic homeostasis.
Volume: 17
Issue: 3
Pages: 277-85
Publication
First Author: Mizushima N
Year: 2010
Journal: Cell
Title: Methods in mammalian autophagy research.
Volume: 140
Issue: 3
Pages: 313-26
Publication
First Author: Friedman LM
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: MicroRNAs are essential for development and function of inner ear hair cells in vertebrates.
Volume: 106
Issue: 19
Pages: 7915-20
Publication
First Author: Zhi JJ
Year: 2023
Journal: J Neurosci
Title: Insufficient Oligodendrocyte Turnover in Optic Nerve Contributes to Age-Related Axon Loss and Visual Deficits.
Volume: 43
Issue: 11
Pages: 1859-1870
Publication
First Author: Luo F
Year: 2020
Journal: EMBO J
Title: Neurexins cluster Ca2+ channels within the presynaptic active zone.
Volume: 39
Issue: 7
Pages: e103208
Publication    
First Author: Bitzenhofer SH
Year: 2022
Journal: Elife
Title: Rapid odor processing by layer 2 subcircuits in lateral entorhinal cortex.
Volume: 11
Publication
First Author: Chen LY
Year: 2017
Journal: Neuron
Title: Conditional Deletion of All Neurexins Defines Diversity of Essential Synaptic Organizer Functions for Neurexins.
Volume: 94
Issue: 3
Pages: 611-625.e4
Publication
First Author: Luo F
Year: 2021
Journal: Nat Commun
Title: Neurexins regulate presynaptic GABAB-receptors at central synapses.
Volume: 12
Issue: 1
Pages: 2380
Publication
First Author: Zhang B
Year: 2018
Journal: J Exp Med
Title: Autism-associated neuroligin-4 mutation selectively impairs glycinergic synaptic transmission in mouse brainstem synapses.
Volume: 215
Issue: 6
Pages: 1543-1553
Publication
First Author: Zhang B
Year: 2016
Journal: J Neurosci
Title: Neuroligins Are Selectively Essential for NMDAR Signaling in Cerebellar Stellate Interneurons.
Volume: 36
Issue: 35
Pages: 9070-83
Publication
First Author: Li X
Year: 2021
Journal: Cell Rep
Title: A circuit of mossy cells controls the efficacy of memory retrieval by Gria2I inhibition of Gria2.
Volume: 34
Issue: 7
Pages: 108741
Publication
First Author: Muñoz W
Year: 2017
Journal: Science
Title: Layer-specific modulation of neocortical dendritic inhibition during active wakefulness.
Volume: 355
Issue: 6328
Pages: 954-959
Publication
First Author: Prasad H
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Amyloid clearance defect in ApoE4 astrocytes is reversed by epigenetic correction of endosomal pH.
Volume: 115
Issue: 28
Pages: E6640-E6649
Publication
First Author: Mohammad RZ
Year: 2022
Journal: Commun Biol
Title: A numerical algorithm for modeling cellular rearrangements in tissue morphogenesis.
Volume: 5
Issue: 1
Pages: 239
Publication
First Author: Madhavan SM
Year: 2022
Journal: Am J Physiol Renal Physiol
Title: Essential role of Wtip in mouse development and maintenance of the glomerular filtration barrier.
Volume: 323
Issue: 3
Pages: F272-F287
Publication
First Author: Zhao Y
Year: 2006
Journal: J Biol Chem
Title: Deletion of core fucosylation on alpha3beta1 integrin down-regulates its functions.
Volume: 281
Issue: 50
Pages: 38343-50
Publication  
First Author: Duan J
Year: 2019
Journal: Front Cell Neurosci
Title: Genetic Deletion of GABAA Receptors Reveals Distinct Requirements of Neurotransmitter Receptors for GABAergic and Glutamatergic Synapse Development.
Volume: 13
Pages: 217
Publication
First Author: Lu W
Year: 2011
Journal: J Neurophysiol
Title: Potentiation of synaptic AMPA receptors induced by the deletion of NMDA receptors requires the GluA2 subunit.
Volume: 105
Issue: 2
Pages: 923-8
Publication
First Author: Horowitz JC
Year: 2008
Journal: Am J Respir Cell Mol Biol
Title: Plasminogen activation induced pericellular fibronectin proteolysis promotes fibroblast apoptosis.
Volume: 38
Issue: 1
Pages: 78-87
Publication
First Author: Tian Y
Year: 2011
Journal: FASEB J
Title: A small-molecule enhancer of autophagy decreases levels of Abeta and APP-CTF via Atg5-dependent autophagy pathway.
Volume: 25
Issue: 6
Pages: 1934-42
Publication
First Author: Wang Y
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Autophagic activity dictates the cellular response to oncogenic RAS.
Volume: 109
Issue: 33
Pages: 13325-30
Publication
First Author: Yamamoto Y
Year: 2021
Journal: Nat Commun
Title: NEK9 regulates primary cilia formation by acting as a selective autophagy adaptor for MYH9/myosin IIA.
Volume: 12
Issue: 1
Pages: 3292
Publication
First Author: Kuo TC
Year: 2011
Journal: Nat Cell Biol
Title: Midbody accumulation through evasion of autophagy contributes to cellular reprogramming and tumorigenicity.
Volume: 13
Issue: 10
Pages: 1214-23
Publication  
First Author: Dumanis SB
Year: 2012
Journal: Mol Neurodegener
Title: FE65 as a link between VLDLR and APP to regulate their trafficking and processing.
Volume: 7
Pages: 9
Publication
First Author: Gutiérrez J
Year: 2015
Journal: PLoS One
Title: RECK-Mediated β1-Integrin Regulation by TGF-β1 Is Critical for Wound Contraction in Mice.
Volume: 10
Issue: 8
Pages: e0135005
Publication  
First Author: Downs AM
Year: 2022
Journal: Neurobiol Dis
Title: Blockade of M4 muscarinic receptors on striatal cholinergic interneurons normalizes striatal dopamine release in a mouse model of TOR1A dystonia.
Volume: 168
Pages: 105699
Publication
First Author: Ida A
Year: 1998
Journal: Eur J Immunol
Title: Multigenic control of lupus-associated antiphospholipid syndrome in a model of (NZW x BXSB) F1 mice.
Volume: 28
Issue: 9
Pages: 2694-703
Publication
First Author: Cheng J
Year: 2020
Journal: Autophagy
Title: Microglial autophagy defect causes parkinson disease-like symptoms by accelerating inflammasome activation in mice.
Volume: 16
Issue: 12
Pages: 2193-2205
Publication
First Author: Tjondrokoesoemo A
Year: 2013
Journal: J Biol Chem
Title: Type 1 inositol (1,4,5)-trisphosphate receptor activates ryanodine receptor 1 to mediate calcium spark signaling in adult mammalian skeletal muscle.
Volume: 288
Issue: 4
Pages: 2103-9
Publication
First Author: Yang F
Year: 2020
Journal: PLoS Genet
Title: Inositol 1,4,5-trisphosphate receptors are essential for fetal-maternal connection and embryo viability.
Volume: 16
Issue: 4
Pages: e1008739
Publication  
First Author: Hamada K
Year: 2022
Journal: Front Endocrinol (Lausanne)
Title: MIEAP and ATG5 are tumor suppressors in a mouse model of BRAFV600E-positive thyroid cancer.
Volume: 13
Pages: 932754