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Search results 1201 to 1300 out of 2547 for Pten

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Category: Publication
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Type Details Score
Publication
36150390 | J:330167
First Author: Mandula JK
Year: 2022
Journal: Cancer Cell
Title: Ablation of the endoplasmic reticulum stress kinase PERK induces paraptosis and type I interferon to promote anti-tumor T cell responses.
Volume: 40
Issue: 10
Pages: 1145-1160.e9
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Publication
32066953 | J:292988
First Author: Wang H
Year: 2020
Journal: Nat Immunol
Title: CD36-mediated metabolic adaptation supports regulatory T cell survival and function in tumors.
Volume: 21
Issue: 3
Pages: 298-308
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Publication
36370710 | J:333386
First Author: Wang X
Year: 2023
Journal: Neuron
Title: Driving axon regeneration by orchestrating neuronal and non-neuronal innate immune responses via the IFNγ-cGAS-STING axis.
Volume: 111
Issue: 2
Pages: 236-255.e7
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Publication
21754979 | J:174838
First Author: Fomchenko EI
Year: 2011
Journal: PLoS One
Title: Recruited cells can become transformed and overtake PDGF-induced murine gliomas in vivo during tumor progression.
Volume: 6
Issue: 7
Pages: e20605
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Publication
36456551 | J:335152
First Author: Werlen G
Year: 2022
Journal: Nat Commun
Title: Dietary glucosamine overcomes the defects in αβ-T cell ontogeny caused by the loss of de novo hexosamine biosynthesis.
Volume: 13
Issue: 1
Pages: 7404
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Publication
27760326 | J:240819
First Author: Kohlhapp FJ
Year: 2016
Journal: Cell Rep
Title: Non-oncogenic Acute Viral Infections Disrupt Anti-cancer Responses and Lead to Accelerated Cancer-Specific Host Death.
Volume: 17
Issue: 4
Pages: 957-965
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Publication
28202614 | J:252719
First Author: Erkes DA
Year: 2017
Journal: J Immunol
Title: Virus-Specific CD8+ T Cells Infiltrate Melanoma Lesions and Retain Function Independently of PD-1 Expression.
Volume: 198
Issue: 7
Pages: 2979-2988
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Publication
27400148 | J:259419
First Author: Riedel A
Year: 2016
Journal: Nat Immunol
Title: Tumor-induced stromal reprogramming drives lymph node transformation.
Volume: 17
Issue: 9
Pages: 1118-27
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Publication
30674530 | J:273224
First Author: Beckmann PJ
Year: 2019
Journal: Cancer Res
Title: Sleeping Beauty Insertional Mutagenesis Reveals Important Genetic Drivers of Central Nervous System Embryonal Tumors.
Volume: 79
Issue: 5
Pages: 905-917
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Publication
29180473 | J:256302
First Author: Brighton HE
Year: 2018
Journal: Cancer Res
Title: New Mechanisms of Resistance to MEK Inhibitors in Melanoma Revealed by Intravital Imaging.
Volume: 78
Issue: 2
Pages: 542-557
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Publication
19879843 | J:157297
First Author: Srinivasan L
Year: 2009
Journal: Cell
Title: PI3 kinase signals BCR-dependent mature B cell survival.
Volume: 139
Issue: 3
Pages: 573-86
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Publication
34788609 | J:321169
First Author: Taranda J
Year: 2021
Journal: Cell Rep
Title: Combined whole-organ imaging at single-cell resolution and immunohistochemical analysis of prostate cancer and its liver and brain metastases.
Volume: 37
Issue: 7
Pages: 110027
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Publication
37310065 | J:359038
First Author: Namikawa M
Year: 2023
Journal: J Pathol
Title: Simultaneous activation of Kras-Akt and Notch pathways induces extrahepatic biliary cancer via the mTORC1 pathway.
Volume: 260
Issue: 4
Pages: 478-492
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Publication
19396167 | J:151203
First Author: King JC
Year: 2009
Journal: Nat Genet
Title: Cooperativity of TMPRSS2-ERG with PI3-kinase pathway activation in prostate oncogenesis.
Volume: 41
Issue: 5
Pages: 524-6
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Publication
17208451 | J:123240
First Author: Nayeem N
Year: 2007
Journal: Mol Cell Neurosci
Title: Hyperphosphorylation of tau and neurofilaments and activation of CDK5 and ERK1/2 in PTEN-deficient cerebella.
Volume: 34
Issue: 3
Pages: 400-8
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Publication
23137704 | J:192239
First Author: Kim HA
Year: 2012
Journal: FEBS Lett
Title: PTEN/MAPK pathways play a key role in platelet-activating factor-induced experimental pulmonary tumor metastasis.
Volume: 586
Issue: 24
Pages: 4296-302
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Publication
28947535 | J:245766
First Author: He F
Year: 2017
Journal: Development
Title: Dysregulated PDGFRα signaling alters coronal suture morphogenesis and leads to craniosynostosis through endochondral ossification.
Volume: 144
Issue: 21
Pages: 4026-4036
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Publication
28349562 | J:243605
First Author: Dosil MA
Year: 2017
Journal: J Pathol
Title: Palbociclib has antitumour effects on Pten-deficient endometrial neoplasias.
Volume: 242
Issue: 2
Pages: 152-164
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Publication
23028043 | J:192734
First Author: Zou Y
Year: 2012
Journal: Mol Cell Biol
Title: The nuclear receptor TLX is required for gliomagenesis within the adult neurogenic niche.
Volume: 32
Issue: 23
Pages: 4811-20
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Publication
28880149 | J:248325
   
First Author: Figlia G
Year: 2017
Journal: Elife
Title: Dual function of the PI3K-Akt-mTORC1 axis in myelination of the peripheral nervous system.
Volume: 6
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Publication
28524854 | J:268124
First Author: Eritja N
Year: 2017
Journal: Cell Death Differ
Title: A Smad3-PTEN regulatory loop controls proliferation and apoptotic responses to TGF-β in mouse endometrium.
Volume: 24
Issue: 8
Pages: 1443-1458
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Publication
32238882 | J:335346
First Author: Uka R
Year: 2020
Journal: Oncogene
Title: Temporal activation of WNT/β-catenin signaling is sufficient to inhibit SOX10 expression and block melanoma growth.
Volume: 39
Issue: 20
Pages: 4132-4154
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Publication
29760047 | J:263944
First Author: Zhang F
Year: 2018
Journal: Cancer Res
Title: Nanoparticles That Reshape the Tumor Milieu Create a Therapeutic Window for Effective T-cell Therapy in Solid Malignancies.
Volume: 78
Issue: 13
Pages: 3718-3730
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19603508 | J:153565
First Author: Woolfenden S
Year: 2009
Journal: Genesis
Title: A Cre/LoxP conditional luciferase reporter transgenic mouse for bioluminescence monitoring of tumorigenesis.
Volume: 47
Issue: 10
Pages: 659-66
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39186687 | J:360596
First Author: MacLeod G
Year: 2024
Journal: Cancer Res
Title: Fitness Screens Map State-Specific Glioblastoma Stem Cell Vulnerabilities.
Volume: 84
Issue: 23
Pages: 3967-3983
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30833574 | J:273261
First Author: Hoeman CM
Year: 2019
Journal: Nat Commun
Title: ACVR1 R206H cooperates with H3.1K27M in promoting diffuse intrinsic pontine glioma pathogenesis.
Volume: 10
Issue: 1
Pages: 1023
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Publication
29437778 | J:262260
     
First Author: Jurmeister S
Year: 2018
Journal: EMBO Mol Med
Title: Identification of potential therapeutic targets in prostate cancer through a cross-species approach.
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Publication
38016952 | J:360598
First Author: Ji Y
Year: 2023
Journal: Nat Commun
Title: The ELAVL3/MYCN positive feedback loop provides a therapeutic target for neuroendocrine prostate cancer.
Volume: 14
Issue: 1
Pages: 7794
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38191471 | J:344323
First Author: Pakula H
Year: 2024
Journal: Nat Commun
Title: Distinct mesenchymal cell states mediate prostate cancer progression.
Volume: 15
Issue: 1
Pages: 363
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Publication
28420791 | J:242231
First Author: Kulkarni S
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Adult enteric nervous system in health is maintained by a dynamic balance between neuronal apoptosis and neurogenesis.
Volume: 114
Issue: 18
Pages: E3709-E3718
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Publication
26058079 | J:222915
First Author: Stratikopoulos EE
Year: 2015
Journal: Cancer Cell
Title: Kinase and BET Inhibitors Together Clamp Inhibition of PI3K Signaling and Overcome Resistance to Therapy.
Volume: 27
Issue: 6
Pages: 837-51
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27294523 | J:237138
First Author: Kwon OJ
Year: 2016
Journal: J Clin Invest
Title: Notch promotes tumor metastasis in a prostate-specific Pten-null mouse model.
Volume: 126
Issue: 7
Pages: 2626-41
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Publication
36131018 | J:335416
First Author: Karras P
Year: 2022
Journal: Nature
Title: A cellular hierarchy in melanoma uncouples growth and metastasis.
Volume: 610
Issue: 7930
Pages: 190-198
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Publication
32686704 | J:298942
First Author: Tagliatela AC
Year: 2020
Journal: Sci Rep
Title: Coronin 1C inhibits melanoma metastasis through regulation of MT1-MMP-containing extracellular vesicle secretion.
Volume: 10
Issue: 1
Pages: 11958
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33910229 | J:308740
First Author: Ren AA
Year: 2021
Journal: Nature
Title: PIK3CA and CCM mutations fuel cavernomas through a cancer-like mechanism.
Volume: 594
Issue: 7862
Pages: 271-276
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25298407 | J:219675
First Author: Bianchi-Frias D
Year: 2015
Journal: Mol Cancer Res
Title: The landscape of somatic chromosomal copy number aberrations in GEM models of prostate carcinoma.
Volume: 13
Issue: 2
Pages: 339-47
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28658205 | J:252222
First Author: Zabala-Letona A
Year: 2017
Journal: Nature
Title: mTORC1-dependent AMD1 regulation sustains polyamine metabolism in prostate cancer.
Volume: 547
Issue: 7661
Pages: 109-113
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23812097 | J:201798
First Author: Kang SG
Year: 2013
Journal: Nat Immunol
Title: MicroRNAs of the miR-17∼92 family are critical regulators of T(FH) differentiation.
Volume: 14
Issue: 8
Pages: 849-57
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18178811 | J:130950
First Author: Janas ML
Year: 2008
Journal: J Immunol
Title: The effect of deleting p110delta on the phenotype and function of PTEN-deficient B cells.
Volume: 180
Issue: 2
Pages: 739-46
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23056544 | J:192099
First Author: Helmy K
Year: 2012
Journal: PLoS One
Title: Identification of global alteration of translational regulation in glioma in vivo.
Volume: 7
Issue: 10
Pages: e46965
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27199435 | J:231882
First Author: Quail DF
Year: 2016
Journal: Science
Title: The tumor microenvironment underlies acquired resistance to CSF-1R inhibition in gliomas.
Volume: 352
Issue: 6288
Pages: aad3018
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37567175 | J:339309
First Author: Chessa TAM
Year: 2023
Journal: Mol Cell
Title: PLEKHS1 drives PI3Ks and remodels pathway homeostasis in PTEN-null prostate.
Volume: 83
Issue: 16
Pages: 2991-3009.e13
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11504907 | J:71306
First Author: Podsypanina K
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: An inhibitor of mTOR reduces neoplasia and normalizes p70/S6 kinase activity in Pten+/- mice.
Volume: 98
Issue: 18
Pages: 10320-5
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10203785 | J:54104
First Author: Maehama T
Year: 1999
Journal: Trends Cell Biol
Title: PTEN: a tumour suppressor that functions as a phospholipid phosphatase.
Volume: 9
Issue: 4
Pages: 125-8
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Publication
17324556 | -
First Author: Xiao Y
Year: 2007
Journal: Cell Signal
Title: PTEN catalysis of phospholipid dephosphorylation reaction follows a two-step mechanism in which the conserved aspartate-92 does not function as the general acid--mechanistic analysis of a familial Cowden disease-associated PTEN mutation.
Volume: 19
Issue: 7
Pages: 1434-45
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Publication
39395421 | J:358349
First Author: Ross JL
Year: 2024
Journal: Immunity
Title: Microglia and monocyte-derived macrophages drive progression of pediatric high-grade gliomas and are transcriptionally shaped by histone mutations.
Volume: 57
Issue: 11
Pages: 2669-2687.e6
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31685822 | J:281598
First Author: Sun Q
Year: 2019
Journal: Nat Commun
Title: A novel mouse model demonstrates that oncogenic melanocyte stem cells engender melanoma resembling human disease.
Volume: 10
Issue: 1
Pages: 5023
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26359368 | J:231492
First Author: Garcia-Rendueles ME
Year: 2015
Journal: Cancer Discov
Title: NF2 Loss Promotes Oncogenic RAS-Induced Thyroid Cancers via YAP-Dependent Transactivation of RAS Proteins and Sensitizes Them to MEK Inhibition.
Volume: 5
Issue: 11
Pages: 1178-93
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35653190 | J:332383
 
First Author: Kumar R
Year: 2022
Journal: J Clin Invest
Title: A mitochondrial unfolded protein response inhibitor suppresses prostate cancer growth in mice via HSP60.
Volume: 132
Issue: 13
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29343435 | J:272341
First Author: Zhao F
Year: 2018
Journal: Immunity
Title: Paracrine Wnt5a-β-Catenin Signaling Triggers a Metabolic Program that Drives Dendritic Cell Tolerization.
Volume: 48
Issue: 1
Pages: 147-160.e7
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21865646 | J:178240
First Author: Goertz MJ
Year: 2011
Journal: J Clin Invest
Title: Foxo1 is required in mouse spermatogonial stem cells for their maintenance and the initiation of spermatogenesis.
Volume: 121
Issue: 9
Pages: 3456-66
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20049710 | J:225033
First Author: Morais VA
Year: 2009
Journal: EMBO Mol Med
Title: Parkinson's disease mutations in PINK1 result in decreased Complex I activity and deficient synaptic function.
Volume: 1
Issue: 2
Pages: 99-111
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23638067 | J:200875
First Author: Siddall HK
Year: 2013
Journal: PLoS One
Title: Loss of PINK1 increases the heart's vulnerability to ischemia-reperfusion injury.
Volume: 8
Issue: 4
Pages: e62400
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30008323 | J:264236
First Author: Zingg D
Year: 2018
Journal: Cancer Cell
Title: EZH2-Mediated Primary Cilium Deconstruction Drives Metastatic Melanoma Formation.
Volume: 34
Issue: 1
Pages: 69-84.e14
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25798619 | J:222273
First Author: Venkatesh A
Year: 2015
Journal: J Clin Invest
Title: Activated mTORC1 promotes long-term cone survival in retinitis pigmentosa mice.
Volume: 125
Issue: 4
Pages: 1446-58
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24823640 | J:210591
First Author: Aytes A
Year: 2014
Journal: Cancer Cell
Title: Cross-species regulatory network analysis identifies a synergistic interaction between FOXM1 and CENPF that drives prostate cancer malignancy.
Volume: 25
Issue: 5
Pages: 638-651
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27565343 | J:236303
First Author: Zhu L
Year: 2016
Journal: Cell
Title: Multi-organ Mapping of Cancer Risk.
Volume: 166
Issue: 5
Pages: 1132-1146.e7
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38416830 | J:345596
First Author: Yang F
Year: 2024
Journal: Sci Adv
Title: An immunosuppressive vascular niche drives macrophage polarization and immunotherapy resistance in glioblastoma.
Volume: 10
Issue: 9
Pages: eadj4678
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34099734 | J:307910
First Author: Brady NJ
Year: 2021
Journal: Nat Commun
Title: Temporal evolution of cellular heterogeneity during the progression to advanced AR-negative prostate cancer.
Volume: 12
Issue: 1
Pages: 3372
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25164012 | J:216695
First Author: Palmer CJ
Year: 2014
Journal: Cancer Res
Title: Zfx facilitates tumorigenesis caused by activation of the Hedgehog pathway.
Volume: 74
Issue: 20
Pages: 5914-24
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34475389 | J:311172
First Author: Schachter NF
Year: 2021
Journal: Nat Commun
Title: Single allele loss-of-function mutations select and sculpt conditional cooperative networks in breast cancer.
Volume: 12
Issue: 1
Pages: 5238
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29949764 | J:271084
First Author: Ozawa T
Year: 2018
Journal: Cell Rep
Title: A De Novo Mouse Model of C11orf95-RELA Fusion-Driven Ependymoma Identifies Driver Functions in Addition to NF-κB.
Volume: 23
Issue: 13
Pages: 3787-3797
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18245377 | J:131932
First Author: Klezovitch O
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: A causal role for ERG in neoplastic transformation of prostate epithelium.
Volume: 105
Issue: 6
Pages: 2105-10
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37024714 | J:334826
First Author: Kim S
Year: 2023
Journal: Sci Rep
Title: Disruptive lysosomal-metabolic signaling and neurodevelopmental deficits that precede Purkinje cell loss in a mouse model of Niemann-Pick Type-C disease.
Volume: 13
Issue: 1
Pages: 5665
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30827887 | J:273246
First Author: Reina-Campos M
Year: 2019
Journal: Cancer Cell
Title: Increased Serine and One-Carbon Pathway Metabolism by PKCλ/ι Deficiency Promotes Neuroendocrine Prostate Cancer.
Volume: 35
Issue: 3
Pages: 385-400.e9
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19948822 | J:156382
First Author: Leav I
Year: 2010
Journal: Am J Pathol
Title: Cytoprotective mitochondrial chaperone TRAP-1 as a novel molecular target in localized and metastatic prostate cancer.
Volume: 176
Issue: 1
Pages: 393-401
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16425198 | J:110412
First Author: Fricke ST
Year: 2006
Journal: Prostate
Title: In vivo magnetic resonance volumetric and spectroscopic analysis of mouse prostate cancer models.
Volume: 66
Issue: 7
Pages: 708-17
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9778245 | J:77008
First Author: Stambolic V
Year: 1998
Journal: Cell
Title: Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN.
Volume: 95
Issue: 1
Pages: 29-39
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17567478 | J:138099
 
First Author: Watanabe S
Year: 2007
Journal: J Gastroenterol Hepatol
Title: Non-alcoholic steatohepatitis and hepatocellular carcinoma: lessons from hepatocyte-specific phosphatase and tensin homolog (PTEN)-deficient mice.
Volume: 22 Suppl 1
Pages: S96-S100
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16214396 | J:118074
First Author: Watanabe S
Year: 2005
Journal: Hepatol Res
Title: Hepatocyte-specific Pten-deficient mice as a novel model for nonalcoholic steatohepatitis and hepatocellular carcinoma.
Volume: 33
Issue: 2
Pages: 161-6
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35514976 | J:325447
 
First Author: Kuttke M
Year: 2022
Journal: Front Immunol
Title: PI3K Signaling in Dendritic Cells Aggravates DSS-Induced Colitis.
Volume: 13
Pages: 695576
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27142333 | J:232792
First Author: Jadali A
Year: 2016
Journal: Biol Open
Title: Activation of PI3K signaling prevents aminoglycoside-induced hair cell death in the murine cochlea.
Volume: 5
Issue: 6
Pages: 698-708
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16982858 | J:139334
First Author: Buckler JL
Year: 2006
Journal: J Immunol
Title: Cutting edge: T cell requirement for CD28 costimulation is due to negative regulation of TCR signals by PTEN.
Volume: 177
Issue: 7
Pages: 4262-6
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26085373 | J:223022
 
First Author: Kalathur M
Year: 2015
Journal: Nat Commun
Title: A chemogenomic screening identifies CK2 as a target for pro-senescence therapy in PTEN-deficient tumours.
Volume: 6
Pages: 7227
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34446716 | J:327666
First Author: Sun Y
Year: 2021
Journal: Nat Commun
Title: PTENα functions as an immune suppressor and promotes immune resistance in PTEN-mutant cancer.
Volume: 12
Issue: 1
Pages: 5147
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10855797 | J:62322
First Author: Kwabi-Addo B
Year: 2000
Journal: DNA Cell Biol
Title: Absence of PTEN/MMAC1 pseudogene in mice.
Volume: 19
Issue: 5
Pages: 301-5
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22179046 | J:178979
First Author: Bronisz A
Year: 2011
Journal: Nat Cell Biol
Title: Reprogramming of the tumour microenvironment by stromal PTEN-regulated miR-320.
Volume: 14
Issue: 2
Pages: 159-67
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35853870 | J:326662
First Author: Hamed AA
Year: 2022
Journal: Nat Commun
Title: A brain precursor atlas reveals the acquisition of developmental-like states in adult cerebral tumours.
Volume: 13
Issue: 1
Pages: 4178
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32894216 | J:347527
   
First Author: Tremblay M
Year: 2020
Journal: Elife
Title: Regulation of stem/progenitor cell maintenance by BMP5 in prostate homeostasis and cancer initiation.
Volume: 9
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Publication
28923960 | J:252910
First Author: Tong P
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: IgH isotype-specific B cell receptor expression influences B cell fate.
Volume: 114
Issue: 40
Pages: E8411-E8420
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34285232 | J:307921
First Author: Jeong SH
Year: 2021
Journal: Nat Commun
Title: Refractoriness of STING therapy is relieved by AKT inhibitor through effective vascular disruption in tumour.
Volume: 12
Issue: 1
Pages: 4405
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33020472 | J:298638
First Author: De Boeck A
Year: 2020
Journal: Nat Commun
Title: Glioma-derived IL-33 orchestrates an inflammatory brain tumor microenvironment that accelerates glioma progression.
Volume: 11
Issue: 1
Pages: 4997
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32639068 | J:297579
First Author: Chen Z
Year: 2020
Journal: Glia
Title: Genetic driver mutations introduced in identical cell-of-origin in murine glioblastoma reveal distinct immune landscapes but similar response to checkpoint blockade.
Volume: 68
Issue: 10
Pages: 2148-2166
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33300045 | J:354474
First Author: Ross JL
Year: 2021
Journal: Brain
Title: Platelet-derived growth factor beta is a potent inflammatory driver in paediatric high-grade glioma.
Volume: 144
Issue: 1
Pages: 53-69
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28836293 | J:252858
First Author: Herting CJ
Year: 2017
Journal: Glia
Title: Genetic driver mutations define the expression signature and microenvironmental composition of high-grade gliomas.
Volume: 65
Issue: 12
Pages: 1914-1926
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37733448 | J:342600
 
First Author: Chen Z
Year: 2023
Journal: J Clin Invest
Title: A paracrine circuit of IL-1β/IL-1R1 between myeloid and tumor cells drives genotype-dependent glioblastoma progression.
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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