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Search results 1301 to 1400 out of 2663 for Psen1

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Type Details Score
Publication
25261995 | J:227827
First Author: Minami SS
Year: 2014
Journal: Nat Med
Title: Progranulin protects against amyloid β deposition and toxicity in Alzheimer's disease mouse models.
Volume: 20
Issue: 10
Pages: 1157-64
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Publication
38624088 | J:350434
First Author: Ahmed C
Year: 2024
Journal: Alzheimers Dement
Title: Peripheral HMGB1 is linked to O(3) pathology of disease-associated astrocytes and amyloid.
Volume: 20
Issue: 5
Pages: 3551-3566
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Publication
19767128 | J:176716
First Author: Mijatovic J
Year: 2011
Journal: Neurobiol Aging
Title: Constitutive Ret signaling is protective for dopaminergic cell bodies but not for axonal terminals.
Volume: 32
Issue: 8
Pages: 1486-94
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Publication
29078331 | J:254186
First Author: Andrew RJ
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Lack of BACE1 S-palmitoylation reduces amyloid burden and mitigates memory deficits in transgenic mouse models of Alzheimer's disease.
Volume: 114
Issue: 45
Pages: E9665-E9674
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Publication
38159571 | J:348203
First Author: Millet A
Year: 2024
Journal: Immunity
Title: An exhausted-like microglial population accumulates in aged and APOE4 genotype Alzheimer's brains.
Volume: 57
Issue: 1
Pages: 153-170.e6
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Publication
38301863 | J:348172
 
First Author: Eisenbaum M
Year: 2024
Journal: Exp Neurol
Title: Repetitive head trauma and apoE4 induce chronic cerebrovascular alterations that impair tau elimination from the brain.
Volume: 374
Pages: 114702
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Publication
33813349 | J:311279
 
First Author: Cacciottolo M
Year: 2021
Journal: Neurobiol Aging
Title: Age, sex, and cerebral microbleeds in EFAD Alzheimer disease mice.
Volume: 103
Pages: 42-51
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Publication
31113487 | J:289681
First Author: Stephen TL
Year: 2019
Journal: Acta Neuropathol Commun
Title: APOE genotype and sex affect microglial interactions with plaques in Alzheimer's disease mice.
Volume: 7
Issue: 1
Pages: 82
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Publication
33178186 | J:311287
 
First Author: Ma QL
Year: 2020
Journal: Front Immunol
Title: The Novel Omega-6 Fatty Acid Docosapentaenoic Acid Positively Modulates Brain Innate Immune Response for Resolving Neuroinflammation at Early and Late Stages of Humanized APOE-Based Alzheimer's Disease Models.
Volume: 11
Pages: 558036
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Publication
32758917 | J:299539
 
First Author: Ringland C
Year: 2020
Journal: Neurobiol Aging
Title: Apolipoprotein E isoforms differentially regulate matrix metallopeptidase 9 function in Alzheimer's disease.
Volume: 95
Pages: 56-68
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Publication
28612048 | J:255879
 
First Author: Moser VA
Year: 2017
Journal: eNeuro
Title: Obesity Accelerates Alzheimer-Related Pathology in APOE4 but not APOE3 Mice.
Volume: 4
Issue: 3
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Publication
31461505 | J:284309
First Author: Hoffman JD
Year: 2019
Journal: PLoS One
Title: Dietary inulin alters the gut microbiome, enhances systemic metabolism and reduces neuroinflammation in an APOE4 mouse model.
Volume: 14
Issue: 8
Pages: e0221828
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Publication
36336241 | J:332022
 
First Author: Ng CAS
Year: 2022
Journal: Neurobiol Dis
Title: Chemotherapy promotes astrocytic response to Aβ deposition, but not Aβ levels, in a mouse model of amyloid and APOE.
Volume: 175
Pages: 105915
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Publication
36871219 | J:337495
First Author: Lee S
Year: 2023
Journal: Cell Rep
Title: APOE modulates microglial immunometabolism in response to age, amyloid pathology, and inflammatory challenge.
Volume: 42
Issue: 3
Pages: 112196
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Publication
23060451 | J:193422
First Author: Youmans KL
Year: 2012
Journal: J Biol Chem
Title: APOE4-specific changes in Aβ accumulation in a new transgenic mouse model of Alzheimer disease.
Volume: 287
Issue: 50
Pages: 41774-86
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Publication
38020764 | J:343135
 
First Author: Balu D
Year: 2023
Journal: Front Aging Neurosci
Title: APOE genotype and sex modulate Alzheimer's disease pathology in aged EFAD transgenic mice.
Volume: 15
Pages: 1279343
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Publication
33168861 | J:300409
First Author: Crivelli SM
Year: 2020
Journal: Sci Rep
Title: Ceramide analog [18F]F-HPA-12 detects sphingolipid disbalance in the brain of Alzheimer's disease transgenic mice by functioning as a metabolic probe.
Volume: 10
Issue: 1
Pages: 19354
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Publication
38868202 | J:349782
First Author: Wang N
Year: 2024
Journal: iScience
Title: Microglial apolipoprotein E particles contribute to neuronal senescence and synaptotoxicity.
Volume: 27
Issue: 6
Pages: 110006
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Publication
26686669 | J:234434
 
First Author: Cacciottolo M
Year: 2016
Journal: Neurobiol Aging
Title: The APOE4 allele shows opposite sex bias in microbleeds and Alzheimer's disease of humans and mice.
Volume: 37
Pages: 47-57
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Publication
31861986 | J:292924
First Author: Maldonado Weng J
Year: 2019
Journal: Mol Neurodegener
Title: Synergistic effects of APOE and sex on the gut microbiome of young EFAD transgenic mice.
Volume: 14
Issue: 1
Pages: 47
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Publication
30509127 | J:288004
First Author: Christensen A
Year: 2019
Journal: FASEB J
Title: APOE genotype affects metabolic and Alzheimer-related outcomes induced by Western diet in female EFAD mice.
Volume: 33
Issue: 3
Pages: 4054-4066
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Publication
28592637 | J:252167
First Author: Berkowitz BA
Year: 2017
Journal: FASEB J
Title: In vivo imaging of prodromal hippocampus CA1 subfield oxidative stress in models of Alzheimer disease and Angelman syndrome.
Volume: 31
Issue: 9
Pages: 4179-4186
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Publication
21356380 | J:169682
First Author: Cui Y
Year: 2011
Journal: Am J Pathol
Title: Genetic ablation of apolipoprotein A-IV accelerates Alzheimer's disease pathogenesis in a mouse model.
Volume: 178
Issue: 3
Pages: 1298-308
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Publication
32514169 | J:307039
First Author: Blanchard JW
Year: 2020
Journal: Nat Med
Title: Reconstruction of the human blood-brain barrier in vitro reveals a pathogenic mechanism of APOE4 in pericytes.
Volume: 26
Issue: 6
Pages: 952-963
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Publication
30514854 | J:269660
First Author: Campagna J
Year: 2018
Journal: Sci Rep
Title: A small molecule ApoE4-targeted therapeutic candidate that normalizes sirtuin 1 levels and improves cognition in an Alzheimer's disease mouse model.
Volume: 8
Issue: 1
Pages: 17574
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Publication
33597265 | J:304463
 
First Author: Xiong M
Year: 2021
Journal: Sci Transl Med
Title: APOE immunotherapy reduces cerebral amyloid angiopathy and amyloid plaques while improving cerebrovascular function.
Volume: 13
Issue: 581
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Publication
36702234 | J:348187
 
First Author: Ballasch I
Year: 2023
Journal: Brain Behav Immun
Title: Ikzf1 as a novel regulator of microglial homeostasis in inflammation and neurodegeneration.
Volume: 109
Pages: 144-161
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Publication
29987201 | J:264893
 
First Author: Eckman J
Year: 2018
Journal: Nutrients
Title: Oxidative Stress Levels in the Brain Are Determined by Post-Mortem Interval and Ante-Mortem Vitamin C State but Not Alzheimer's Disease Status.
Volume: 10
Issue: 7
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Publication
26200696 | J:279975
First Author: Ye B
Year: 2015
Journal: Glia
Title: Dual pathways mediate β-amyloid stimulated glutathione release from astrocytes.
Volume: 63
Issue: 12
Pages: 2208-19
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Publication
35328727 | J:348537
 
First Author: Gutiérrez IL
Year: 2022
Journal: Int J Mol Sci
Title: CCL2 Inhibition of Pro-Resolving Mediators Potentiates Neuroinflammation in Astrocytes.
Volume: 23
Issue: 6
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Publication
38687251 | J:351573
First Author: Sasner M
Year: 2024
Journal: Alzheimers Dement
Title: In vivo validation of late-onset Alzheimer's disease genetic risk factors.
Volume: 20
Issue: 7
Pages: 4970-4984
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Publication
22958823 | J:325329
First Author: Yoon SO
Year: 2012
Journal: Neuron
Title: JNK3 perpetuates metabolic stress induced by Aβ peptides.
Volume: 75
Issue: 5
Pages: 824-37
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Publication
38382624 | J:348218
First Author: Wang M
Year: 2024
Journal: Biochim Biophys Acta Mol Basis Dis
Title: GDI2 deletion alleviates neurodegeneration and memory loss in the 5xFAD mice model of Alzheimer's disease.
Volume: 1870
Issue: 4
Pages: 167093
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Publication
38746665 | J:349434
First Author: Chen Y
Year: 2024
Journal: iScience
Title: A cingulate-hippocampal circuit mediates early depressive-like behavior in the mouse model of Alzheimer disease.
Volume: 27
Issue: 5
Pages: 109778
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Publication
28361984 | J:272779
 
First Author: Colié S
Year: 2017
Journal: Sci Rep
Title: Neuronal p38α mediates synaptic and cognitive dysfunction in an Alzheimer's mouse model by controlling β-amyloid production.
Volume: 7
Pages: 45306
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Publication
35987206 | J:329976
First Author: Adaikkan C
Year: 2022
Journal: Neuron
Title: Alterations in a cross-hemispheric circuit associates with novelty discrimination deficits in mouse models of neurodegeneration.
Volume: 110
Issue: 19
Pages: 3091-3105.e9
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Publication
24889041 | J:218077
First Author: Devi L
Year: 2014
Journal: Neurobiol Aging
Title: PERK mediates eIF2α phosphorylation responsible for BACE1 elevation, CREB dysfunction and neurodegeneration in a mouse model of Alzheimer's disease.
Volume: 35
Issue: 10
Pages: 2272-81
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Publication
32494656 | J:349853
First Author: Kim S
Year: 2020
Journal: Sci Adv
Title: Dynamic Fas signaling network regulates neural stem cell proliferation and memory enhancement.
Volume: 6
Issue: 17
Pages: eaaz9691
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Publication
17409228 | J:119403
First Author: Zhao J
Year: 2007
Journal: J Neurosci
Title: Beta-site amyloid precursor protein cleaving enzyme 1 levels become elevated in neurons around amyloid plaques: implications for Alzheimer's disease pathogenesis.
Volume: 27
Issue: 14
Pages: 3639-49
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Publication
17258906 | J:119002
First Author: Ohno M
Year: 2007
Journal: Neurobiol Dis
Title: BACE1 gene deletion prevents neuron loss and memory deficits in 5XFAD APP/PS1 transgenic mice.
Volume: 26
Issue: 1
Pages: 134-45
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Publication
34020948 | J:347919
 
First Author: Da Mesquita S
Year: 2021
Journal: Sci Adv
Title: Aging-associated deficit in CCR7 is linked to worsened glymphatic function, cognition, neuroinflammation, and β-amyloid pathology.
Volume: 7
Issue: 21
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26619118 | J:229820
First Author: Storck SE
Year: 2016
Journal: J Clin Invest
Title: Endothelial LRP1 transports amyloid-β(1-42) across the blood-brain barrier.
Volume: 126
Issue: 1
Pages: 123-36
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Publication
28496400 | J:312462
 
First Author: Herr UM
Year: 2017
Journal: Front Mol Neurosci
Title: LRP1 Modulates APP Intraneuronal Transport and Processing in Its Monomeric and Dimeric State.
Volume: 10
Pages: 118
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Publication
23826707 | J:210209
First Author: Sesele K
Year: 2013
Journal: Aging Cell
Title: Conditional inactivation of nicastrin restricts amyloid deposition in an Alzheimer's disease mouse model.
Volume: 12
Issue: 6
Pages: 1032-40
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Publication
34433553 | J:311257
 
First Author: Cheng J
Year: 2021
Journal: Sci Adv
Title: Microglial Calhm2 regulates neuroinflammation and contributes to Alzheimer's disease pathology.
Volume: 7
Issue: 35
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Publication
36347423 | J:334400
 
First Author: Gallwitz L
Year: 2022
Journal: Neurobiol Dis
Title: Cathepsin D: Analysis of its potential role as an amyloid beta degrading protease.
Volume: 175
Pages: 105919
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Publication
35353567 | J:338291
First Author: Xia Y
Year: 2022
Journal: Sci Adv
Title: Neuronal C/EBPβ/AEP pathway shortens life span via selective GABAnergic neuronal degeneration by FOXO repression.
Volume: 8
Issue: 13
Pages: eabj8658
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Publication
30195729 | J:348520
 
First Author: Aparicio N
Year: 2018
Journal: Biochem Pharmacol
Title: Role of interleukin 1-beta in the inflammatory response in a fatty acid amide hydrolase-knockout mouse model of Alzheimer's disease.
Volume: 157
Pages: 202-209
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Publication
26362942 | J:232248
First Author: Vázquez C
Year: 2015
Journal: Neurobiol Aging
Title: Endocannabinoid regulation of amyloid-induced neuroinflammation.
Volume: 36
Issue: 11
Pages: 3008-3019
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Publication
34587978 | J:351266
First Author: Ruiz-Pérez G
Year: 2021
Journal: J Neuroinflammation
Title: Potentiation of amyloid beta phagocytosis and amelioration of synaptic dysfunction upon FAAH deletion in a mouse model of Alzheimer's disease.
Volume: 18
Issue: 1
Pages: 223
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Publication
35464490 | J:325601
 
First Author: Islam J
Year: 2022
Journal: Front Immunol
Title: GPCR19 Regulates P2X7R-Mediated NLRP3 Inflammasomal Activation of Microglia by Amyloid β in a Mouse Model of Alzheimer's Disease.
Volume: 13
Pages: 766919
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Publication
29200205 | J:311456
First Author: He Z
Year: 2018
Journal: Nat Med
Title: Amyloid-β plaques enhance Alzheimer's brain tau-seeded pathologies by facilitating neuritic plaque tau aggregation.
Volume: 24
Issue: 1
Pages: 29-38
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Publication
33980987 | J:311266
First Author: Dong Y
Year: 2021
Journal: Commun Biol
Title: The anesthetic sevoflurane induces tau trafficking from neurons to microglia.
Volume: 4
Issue: 1
Pages: 560
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Publication
38539014 | J:348881
First Author: Wilson EN
Year: 2024
Journal: Nat Neurosci
Title: TREM1 disrupts myeloid bioenergetics and cognitive function in aging and Alzheimer disease mouse models.
Volume: 27
Issue: 5
Pages: 873-885
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Publication
31358853 | J:284801
First Author: Wang M
Year: 2019
Journal: Sci Rep
Title: Acute restraint stress reverses impaired LTP in the hippocampal CA1 region in mouse models of Alzheimer's disease.
Volume: 9
Issue: 1
Pages: 10955
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Publication
25361083 | J:258839
First Author: Byun J
Year: 2015
Journal: Cell Death Differ
Title: CR6-interacting factor 1 is a key regulator in Aβ-induced mitochondrial disruption and pathogenesis of Alzheimer's disease.
Volume: 22
Issue: 6
Pages: 959-73
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Publication
37494443 | J:338544
First Author: Im E
Year: 2023
Journal: Sci Adv
Title: Lysosomal dysfunction in Down syndrome and Alzheimer mouse models is caused by v-ATPase inhibition by Tyr(682)-phosphorylated APP βCTF.
Volume: 9
Issue: 30
Pages: eadg1925
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26452999 | J:232372
First Author: Son SM
Year: 2015
Journal: Neurobiol Aging
Title: Thrombospondin-1 prevents amyloid beta-mediated synaptic pathology in Alzheimer's disease.
Volume: 36
Issue: 12
Pages: 3214-3227
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Publication
36918976 | J:351754
First Author: Chen L
Year: 2023
Journal: Alzheimers Res Ther
Title: Attenuation of Alzheimer's brain pathology in 5XFAD mice by PTH(1-34), a peptide of parathyroid hormone.
Volume: 15
Issue: 1
Pages: 53
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Publication
31759806 | J:283375
First Author: Bassil F
Year: 2020
Journal: Neuron
Title: Amyloid-Beta (Aβ) Plaques Promote Seeding and Spreading of Alpha-Synuclein and Tau in a Mouse Model of Lewy Body Disorders with Aβ Pathology.
Volume: 105
Issue: 2
Pages: 260-275.e6
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Publication
37549281 | J:347280
First Author: Nakano-Kobayashi A
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: Astrocyte-targeting therapy rescues cognitive impairment caused by neuroinflammation via the Nrf2 pathway.
Volume: 120
Issue: 33
Pages: e2303809120
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Publication
34977020 | J:361428
 
First Author: Zou Y
Year: 2021
Journal: Front Cell Dev Biol
Title: Programmed Cell Death Protein 1 Blockade Reduces Glycogen Synthase Kinase 3β Activity and Tau Hyperphosphorylation in Alzheimer's Disease Mouse Models.
Volume: 9
Pages: 769229
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31611761 | J:283217
 
First Author: Volkman R
Year: 2019
Journal: Front Neurosci
Title: Myeloperoxidase Deficiency Inhibits Cognitive Decline in the 5XFAD Mouse Model of Alzheimer's Disease.
Volume: 13
Pages: 990
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Publication
36306735 | J:333070
First Author: Wang S
Year: 2022
Journal: Cell
Title: TREM2 drives microglia response to amyloid-β via SYK-dependent and -independent pathways.
Volume: 185
Issue: 22
Pages: 4153-4169.e19
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Publication
37349834 | J:348212
First Author: Dong X
Year: 2023
Journal: J Neuroinflammation
Title: Ogt-mediated O-GlcNAcylation inhibits astrocytes activation through modulating NF-κB signaling pathway.
Volume: 20
Issue: 1
Pages: 146
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Publication
32457323 | J:293272
First Author: Kalovyrna N
Year: 2020
Journal: Sci Rep
Title: A 3'UTR modification of the TNF-α mouse gene increases peripheral TNF-α and modulates the Alzheimer-like phenotype in 5XFAD mice.
Volume: 10
Issue: 1
Pages: 8670
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Publication
26993139 | J:313426
First Author: Sadleir KR
Year: 2016
Journal: Acta Neuropathol
Title: Presynaptic dystrophic neurites surrounding amyloid plaques are sites of microtubule disruption, BACE1 elevation, and increased Aβ generation in Alzheimer's disease.
Volume: 132
Issue: 2
Pages: 235-256
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Publication
37143090 | J:357334
First Author: Zhou J
Year: 2023
Journal: Mol Neurodegener
Title: BACE1 regulates expression of Clusterin in astrocytes for enhancing clearance of β-amyloid peptides.
Volume: 18
Issue: 1
Pages: 31
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20886088 | J:165103
First Author: Devi L
Year: 2010
Journal: PLoS One
Title: Phospho-eIF2α level is important for determining abilities of BACE1 reduction to rescue cholinergic neurodegeneration and memory defects in 5XFAD mice.
Volume: 5
Issue: 9
Pages: e12974
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26314636 | J:227527
 
First Author: Devi L
Year: 2015
Journal: Neuroscience
Title: Effects of BACE1 haploinsufficiency on APP processing and Aβ concentrations in male and female 5XFAD Alzheimer mice at different disease stages.
Volume: 307
Pages: 128-37
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21933711 | J:179837
First Author: Devi L
Year: 2012
Journal: Neurobiol Dis
Title: Mitochondrial dysfunction and accumulation of the β-secretase-cleaved C-terminal fragment of APP in Alzheimer's disease transgenic mice.
Volume: 45
Issue: 1
Pages: 417-24
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30315100 | J:272882
First Author: Sadleir KR
Year: 2018
Journal: J Biol Chem
Title: ER stress is not elevated in the 5XFAD mouse model of Alzheimer's disease.
Volume: 293
Issue: 48
Pages: 18434-18443
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20092558 | J:158363
First Author: Devi L
Year: 2010
Journal: Eur J Neurosci
Title: Genetic reductions of beta-site amyloid precursor protein-cleaving enzyme 1 and amyloid-beta ameliorate impairment of conditioned taste aversion memory in 5XFAD Alzheimer's disease model mice.
Volume: 31
Issue: 1
Pages: 110-8
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23820808 | J:263411
First Author: Kandalepas PC
Year: 2013
Journal: Acta Neuropathol
Title: The Alzheimer's β-secretase BACE1 localizes to normal presynaptic terminals and to dystrophic presynaptic terminals surrounding amyloid plaques.
Volume: 126
Issue: 3
Pages: 329-52
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38987437 | J:351874
First Author: Illouz T
Year: 2024
Journal: Sci Rep
Title: Unbiased analysis of spatial learning strategies in a modified Barnes maze using convolutional neural networks.
Volume: 14
Issue: 1
Pages: 15944
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39269584 | J:360160
     
First Author: Taha HB
Year: 2024
Journal: Geroscience
Title: Activation of the muscle-to-brain axis ameliorates neurocognitive deficits in an Alzheimer's disease mouse model via enhancing neurotrophic and synaptic signaling.
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38012646 | J:343590
First Author: Kim N
Year: 2023
Journal: J Neuroinflammation
Title: Inhibition of microfold cells ameliorates early pathological phenotypes by modulating microglial functions in Alzheimer's disease mouse model.
Volume: 20
Issue: 1
Pages: 282
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39313544 | J:359214
First Author: Saeki K
Year: 2024
Journal: Nat Immunol
Title: IRF8 defines the epigenetic landscape in postnatal microglia, thereby directing their transcriptome programs.
Volume: 25
Issue: 10
Pages: 1928-1942
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31800167 | J:298441
First Author: Lee J
Year: 2020
Journal: Aging Cell
Title: Inhibition of REV-ERBs stimulates microglial amyloid-beta clearance and reduces amyloid plaque deposition in the 5XFAD mouse model of Alzheimer's disease.
Volume: 19
Issue: 2
Pages: e13078
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38123547 | J:348469
First Author: Lee J
Year: 2023
Journal: Nat Commun
Title: ANKS1A regulates LDL receptor-related protein 1 (LRP1)-mediated cerebrovascular clearance in brain endothelial cells.
Volume: 14
Issue: 1
Pages: 8463
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31914599 | J:299529
First Author: Wu Y
Year: 2020
Journal: FASEB J
Title: BHBA treatment improves cognitive function by targeting pleiotropic mechanisms in transgenic mouse model of Alzheimer's disease.
Volume: 34
Issue: 1
Pages: 1412-1429
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Publication
33011810 | J:352669
First Author: Kozyrev N
Year: 2020
Journal: J Neuropathol Exp Neurol
Title: Infiltrating Hematogenous Macrophages Aggregate Around β-Amyloid Plaques in an Age- and Sex-Dependent Manner in a Mouse Model of Alzheimer Disease.
Volume: 79
Issue: 11
Pages: 1147-1162
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36563667 | J:337510
First Author: Bhatia HS
Year: 2022
Journal: Cell
Title: Spatial proteomics in three-dimensional intact specimens.
Volume: 185
Issue: 26
Pages: 5040-5058.e19
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37562402 | J:339343
First Author: Kolabas ZI
Year: 2023
Journal: Cell
Title: Distinct molecular profiles of skull bone marrow in health and neurological disorders.
Volume: 186
Issue: 17
Pages: 3706-3725.e29
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