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Search results 1401 to 1500 out of 5246 for App

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Category: Publication
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Type Details Score
Publication
19815012 | J:156614
First Author: Perucho J
Year: 2010
Journal: Exp Neurol
Title: The effects of parkin suppression on the behaviour, amyloid processing, and cell survival in APP mutant transgenic mice.
Volume: 221
Issue: 1
Pages: 54-67
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Publication
27249364 | J:239910
 
First Author: Beglopoulos V
Year: 2016
Journal: Nat Commun
Title: Early detection of cryptic memory and glucose uptake deficits in pre-pathological APP mice.
Volume: 7
Pages: 11761
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Publication
26581893 | J:228025
 
First Author: Wang J
Year: 2015
Journal: Nat Commun
Title: TRPC6 specifically interacts with APP to inhibit its cleavage by γ-secretase and reduce Aβ production.
Volume: 6
Pages: 8876
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Publication
35830807 | J:328785
First Author: Bai N
Year: 2022
Journal: Cell Rep
Title: Inhibition of SIRT2 promotes APP acetylation and ameliorates cognitive impairment in APP/PS1 transgenic mice.
Volume: 40
Issue: 2
Pages: 111062
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Publication
29955650 | J:351926
 
First Author: Teich AF
Year: 2018
Journal: Alzheimers Dement (N Y)
Title: Translational inhibition of APP by Posiphen: Efficacy, pharmacodynamics, and pharmacokinetics in the APP/PS1 mouse.
Volume: 4
Pages: 37-45
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Publication
34757693 | J:351605
First Author: Sawa M
Year: 2022
Journal: Alzheimers Dement
Title: Impact of increased APP gene dose in Down syndrome and the Dp16 mouse model.
Volume: 18
Issue: 6
Pages: 1203-1234
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Publication
21651910 | J:174222
First Author: León-Otegui M
Year: 2011
Journal: FEBS Lett
Title: Opposite effects of P2X7 and P2Y2 nucleotide receptors on α-secretase-dependent APP processing in Neuro-2a cells.
Volume: 585
Issue: 14
Pages: 2255-62
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Publication
23897889 | J:201637
First Author: Fu MM
Year: 2013
Journal: J Cell Biol
Title: JIP1 regulates the directionality of APP axonal transport by coordinating kinesin and dynein motors.
Volume: 202
Issue: 3
Pages: 495-508
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Publication
24810883 | J:214104
 
First Author: Jin G
Year: 2014
Journal: Neurosci Lett
Title: Xanthoceraside rescues learning and memory deficits through attenuating beta-amyloid deposition and tau hyperphosphorylation in APP mice.
Volume: 573
Pages: 58-63
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Publication
27072891 | J:240851
 
First Author: Sun M
Year: 2016
Journal: Neurobiol Dis
Title: The polarity protein Par3 regulates APP trafficking and processing through the endocytic adaptor protein Numb.
Volume: 93
Pages: 1-11
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Publication
29728560 | J:263719
First Author: Nagata K
Year: 2018
Journal: Nat Commun
Title: Generation of App knock-in mice reveals deletion mutations protective against Alzheimer's disease-like pathology.
Volume: 9
Issue: 1
Pages: 1800
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Publication
24373968 | J:207508
First Author: Ye X
Year: 2014
Journal: Cell Rep
Title: Snapin-mediated BACE1 retrograde transport is essential for its degradation in lysosomes and regulation of APP processing in neurons.
Volume: 6
Issue: 1
Pages: 24-31
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Publication
33412147 | J:307759
 
First Author: Liu M
Year: 2021
Journal: Brain Res
Title: Covert strokes prior to Alzheimer's disease onset accelerate peri-lesional pathology but not cognitive deficits in an inducible APP mouse model.
Volume: 1754
Pages: 147233
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Publication
21514441 | J:171581
First Author: Lord A
Year: 2011
Journal: Am J Pathol
Title: Observations in APP bitransgenic mice suggest that diffuse and compact plaques form via independent processes in Alzheimer's disease.
Volume: 178
Issue: 5
Pages: 2286-98
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Publication
18192084 | J:152959
First Author: Philipson O
Year: 2009
Journal: Neurobiol Aging
Title: A highly insoluble state of Abeta similar to that of Alzheimer's disease brain is found in Arctic APP transgenic mice.
Volume: 30
Issue: 9
Pages: 1393-405
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Publication
27791018 | J:238803
First Author: Katsouri L
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: PPARγ-coactivator-1α gene transfer reduces neuronal loss and amyloid-β generation by reducing β-secretase in an Alzheimer's disease model.
Volume: 113
Issue: 43
Pages: 12292-12297
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Publication
20505099 | J:160819
First Author: McAllister C
Year: 2010
Journal: J Neurosci
Title: Genetic targeting aromatase in male amyloid precursor protein transgenic mice down-regulates beta-secretase (BACE1) and prevents Alzheimer-like pathology and cognitive impairment.
Volume: 30
Issue: 21
Pages: 7326-34
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Publication
26710318 | J:231480
First Author: Kim J
Year: 2016
Journal: J Neurochem
Title: miR-186 is decreased in aged brain and suppresses BACE1 expression.
Volume: 137
Issue: 3
Pages: 436-45
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Publication
17576410 | J:129458
First Author: Kim DY
Year: 2007
Journal: Nat Cell Biol
Title: BACE1 regulates voltage-gated sodium channels and neuronal activity.
Volume: 9
Issue: 7
Pages: 755-64
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Publication
26283960 | J:288950
 
First Author: Dong WG
Year: 2015
Journal: Front Aging Neurosci
Title: Electroacupuncture Reduces Aβ Production and BACE1 Expression in SAMP8 Mice.
Volume: 7
Pages: 148
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Publication
30837353 | J:292991
 
First Author: Haroon MM
Year: 2019
Journal: J Biosci
Title: Delivery of BACE1 siRNA mediated by TARBP-BTP fusion protein reduces β-amyloid deposits in a transgenic mouse model of Alzheimer's disease.
Volume: 44
Issue: 1
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Publication
22204380 | J:315486
 
First Author: Rajapaksha TW
Year: 2011
Journal: Mol Neurodegener
Title: The Alzheimer's β-secretase enzyme BACE1 is required for accurate axon guidance of olfactory sensory neurons and normal glomerulus formation in the olfactory bulb.
Volume: 6
Pages: 88
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Publication
22249458 | J:318112
First Author: Park MH
Year: 2012
Journal: J Neuropathol Exp Neurol
Title: Mutant presenilin 2 increases β-secretase activity through reactive oxygen species-dependent activation of extracellular signal-regulated kinase.
Volume: 71
Issue: 2
Pages: 130-9
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Publication
25955795 | J:329858
First Author: Yang G
Year: 2015
Journal: Mol Med Rep
Title: MicroRNA-29c targets β-site amyloid precursor protein-cleaving enzyme 1 and has a neuroprotective role in vitro and in vivo.
Volume: 12
Issue: 2
Pages: 3081-8
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Publication
22042227 | J:328041
First Author: Treiber H
Year: 2012
Journal: Mol Psychiatry
Title: BACE1 in central nervous system myelination revisited.
Volume: 17
Issue: 3
Pages: 237-9
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Publication
19944081 | J:158540
 
First Author: Rustay NR
Year: 2010
Journal: Brain Res
Title: Mice expressing the Swedish APP mutation on a 129 genetic background demonstrate consistent behavioral deficits and pathological markers of Alzheimer's disease.
Volume: 1311
Pages: 136-47
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Publication
28941799 | J:254181
First Author: Zandl-Lang M
Year: 2018
Journal: Biochim Biophys Acta
Title: Regulatory effects of simvastatin and apoJ on APP processing and amyloid-β clearance in blood-brain barrier endothelial cells.
Volume: 1863
Issue: 1
Pages: 40-60
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Publication
15006688 | J:128772
First Author: Gureviciene I
Year: 2004
Journal: Neurobiol Dis
Title: Normal induction but accelerated decay of LTP in APP + PS1 transgenic mice.
Volume: 15
Issue: 2
Pages: 188-95
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Publication
11021833 | J:129692
First Author: Van Dorpe J
Year: 2000
Journal: Am J Pathol
Title: Prominent cerebral amyloid angiopathy in transgenic mice overexpressing the london mutant of human APP in neurons.
Volume: 157
Issue: 4
Pages: 1283-98
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Publication
11746377 | J:162842
First Author: Rockenstein E
Year: 2001
Journal: J Neurosci Res
Title: Early formation of mature amyloid-beta protein deposits in a mutant APP transgenic model depends on levels of Abeta(1-42).
Volume: 66
Issue: 4
Pages: 573-82
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Publication
29899726 | J:310235
 
First Author: Stanga S
Year: 2018
Journal: Front Neurol
Title: A Role for GDNF and Soluble APP as Biomarkers of Amyotrophic Lateral Sclerosis Pathophysiology.
Volume: 9
Pages: 384
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Publication
22206846 | J:188315
First Author: Morales-Corraliza J
Year: 2012
Journal: Neurobiol Aging
Title: Calpastatin modulates APP processing in the brains of β-amyloid depositing but not wild-type mice.
Volume: 33
Issue: 6
Pages: 1125.e9-18
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Publication
33203136 | J:311965
 
First Author: Marttinen M
Year: 2020
Journal: Cells
Title: Presynaptic Vesicle Protein SEPTIN5 Regulates the Degradation of APP C-Terminal Fragments and the Levels of Aβ.
Volume: 9
Issue: 11
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Publication
29531801 | J:351931
 
First Author: Matthes F
Year: 2018
Journal: Cell Death Discov
Title: Inhibition of the MID1 protein complex: a novel approach targeting APP protein synthesis.
Volume: 4
Pages: 4
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Publication
34228639 | J:327665
 
First Author: Sáez-Orellana F
Year: 2021
Journal: JCI Insight
Title: Regulation of PPARα by APP in Alzheimer disease affects the pharmacological modulation of synaptic activity.
Volume: 6
Issue: 16
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Publication
27459925 | J:239035
 
First Author: Beckmann N
Year: 2016
Journal: Neurobiol Aging
Title: Longitudinal noninvasive magnetic resonance imaging of brain microhemorrhages in BACE inhibitor-treated APP transgenic mice.
Volume: 45
Pages: 50-60
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Publication
32475008 | J:303141
First Author: Schnöder L
Year: 2020
Journal: FASEB J
Title: Neuronal deficiency of p38α-MAPK ameliorates symptoms and pathology of APP or Tau-transgenic Alzheimer's mouse models.
Volume: 34
Issue: 7
Pages: 9628-9649
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Publication
39744941 | J:361238
 
First Author: Tian Q
Year: 2025
Journal: J Clin Invest
Title: APP lysine 612 lactylation ameliorates amyloid pathology and memory decline in Alzheimer's disease.
Volume: 135
Issue: 1
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Publication
21829458 | J:284814
First Author: Bianchi FT
Year: 2011
Journal: PLoS One
Title: The collagen chaperone HSP47 is a new interactor of APP that affects the levels of extracellular beta-amyloid peptides.
Volume: 6
Issue: 7
Pages: e22370
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Publication
24992504 | J:218929
First Author: Sadleir KR
Year: 2014
Journal: PLoS One
Title: Genetic inhibition of phosphorylation of the translation initiation factor eIF2α does not block Aβ-dependent elevation of BACE1 and APP levels or reduce amyloid pathology in a mouse model of Alzheimer's disease.
Volume: 9
Issue: 7
Pages: e101643
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Publication
28704727 | J:326004
 
First Author: Rojo AI
Year: 2017
Journal: Redox Biol
Title: NRF2 deficiency replicates transcriptomic changes in Alzheimer's patients and worsens APP and TAU pathology.
Volume: 13
Pages: 444-451
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Publication
29729423 | J:264741
 
First Author: Adalbert R
Year: 2018
Journal: Neurobiol Aging
Title: Interaction between a MAPT variant causing frontotemporal dementia and mutant APP affects axonal transport.
Volume: 68
Pages: 68-75
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Publication
12032347 | J:76863
First Author: Lee JY
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Contribution by synaptic zinc to the gender-disparate plaque formation in human Swedish mutant APP transgenic mice.
Volume: 99
Issue: 11
Pages: 7705-10
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Publication
22892246 | J:193347
First Author: Bard F
Year: 2012
Journal: Exp Neurol
Title: Sustained levels of antibodies against Aβ in amyloid-rich regions of the CNS following intravenous dosing in human APP transgenic mice.
Volume: 238
Issue: 1
Pages: 38-43
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Publication
26558367 | J:281484
 
First Author: Späni C
Year: 2015
Journal: Acta Neuropathol Commun
Title: Reduced β-amyloid pathology in an APP transgenic mouse model of Alzheimer's disease lacking functional B and T cells.
Volume: 3
Pages: 71
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Publication
28275722 | J:258181
First Author: Hamm V
Year: 2017
Journal: Sci Adv
Title: Differential contribution of APP metabolites to early cognitive deficits in a TgCRND8 mouse model of Alzheimer's disease.
Volume: 3
Issue: 2
Pages: e1601068
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Publication
22056484 | J:180187
First Author: Luccarini I
Year: 2012
Journal: Neurosci Lett
Title: Aβ plaque-associated glial reaction as a determinant of apoptotic neuronal death and cortical gliogenesis: a study in APP mutant mice.
Volume: 506
Issue: 1
Pages: 94-9
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Publication
16251420 | J:102400
First Author: Zhang B
Year: 2005
Journal: Am J Pathol
Title: Impaired rapid eye movement sleep in the Tg2576 APP murine model of Alzheimer's disease with injury to pedunculopontine cholinergic neurons.
Volume: 167
Issue: 5
Pages: 1361-9
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Publication
26510953 | J:329765
First Author: Fitz NF
Year: 2015
Journal: Brain
Title: Opposing effects of Apoe/Apoa1 double deletion on amyloid-β pathology and cognitive performance in APP mice.
Volume: 138
Issue: Pt 12
Pages: 3699-715
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Publication
15147524 | J:92214
First Author: Li F
Year: 2004
Journal: J Neurochem
Title: Increased plaque burden in brains of APP mutant MnSOD heterozygous knockout mice.
Volume: 89
Issue: 5
Pages: 1308-12
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Publication
29545742 | J:276741
 
First Author: Yoshikawa M
Year: 2018
Journal: Front Neurosci
Title: Tau Depletion in APP Transgenic Mice Attenuates Task-Related Hyperactivation of the Hippocampus and Differentially Influences Locomotor Activity and Spatial Memory.
Volume: 12
Pages: 124
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Publication
21558417 | J:183073
First Author: Kim MY
Year: 2011
Journal: J Cell Sci
Title: Regulation of Notch1 signaling by the APP intracellular domain facilitates degradation of the Notch1 intracellular domain and RBP-Jk.
Volume: 124
Issue: Pt 11
Pages: 1831-43
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Publication
33822840 | J:343865
 
First Author: Zhang X
Year: 2021
Journal: J Exp Med
Title: An APP ectodomain mutation outside of the Aβ domain promotes Aβ production in vitro and deposition in vivo.
Volume: 218
Issue: 6
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Publication
38626765 | J:349479
First Author: Bretou M
Year: 2024
Journal: Dev Cell
Title: Accumulation of APP C-terminal fragments causes endolysosomal dysfunction through the dysregulation of late endosome to lysosome-ER contact sites.
Volume: 59
Issue: 12
Pages: 1571-1592.e9
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Publication
21907142 | J:176653
First Author: Esterházy D
Year: 2011
Journal: Cell Metab
Title: Bace2 is a β cell-enriched protease that regulates pancreatic β cell function and mass.
Volume: 14
Issue: 3
Pages: 365-77
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Publication
26563932 | J:259424
 
First Author: Natunen T
Year: 2016
Journal: Neurobiol Dis
Title: Relationship between ubiquilin-1 and BACE1 in human Alzheimer's disease and APdE9 transgenic mouse brain and cell-based models.
Volume: 85
Pages: 187-205
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Publication
21190943 | J:170564
First Author: Kim DY
Year: 2011
Journal: J Biol Chem
Title: Reduced sodium channel Na(v)1.1 levels in BACE1-null mice.
Volume: 286
Issue: 10
Pages: 8106-16
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Publication
23173743 | J:285096
 
First Author: Torres M
Year: 2012
Journal: Mol Neurodegener
Title: Defective lysosomal proteolysis and axonal transport are early pathogenic events that worsen with age leading to increased APP metabolism and synaptic Abeta in transgenic APP/PS1 hippocampus.
Volume: 7
Pages: 59
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11279131 | J:230384
First Author: Zambrano N
Year: 2001
Journal: J Biol Chem
Title: The beta-amyloid precursor protein APP is tyrosine-phosphorylated in cells expressing a constitutively active form of the Abl protoncogene.
Volume: 276
Issue: 23
Pages: 19787-92
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Publication
18374587 | J:136832
First Author: Gavín R
Year: 2008
Journal: Neurobiol Dis
Title: Fibrillar prion peptide PrP(106-126) treatment induces Dab1 phosphorylation and impairs APP processing and Abeta production in cortical neurons.
Volume: 30
Issue: 2
Pages: 243-54
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Publication
19101630 | J:146301
First Author: Simón AM
Year: 2009
Journal: Neurobiol Dis
Title: Overexpression of wild-type human APP in mice causes cognitive deficits and pathological features unrelated to Abeta levels.
Volume: 33
Issue: 3
Pages: 369-78
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Publication
30704515 | J:273177
First Author: Gerber H
Year: 2019
Journal: Acta Neuropathol Commun
Title: The APMAP interactome reveals new modulators of APP processing and beta-amyloid production that are altered in Alzheimer's disease.
Volume: 7
Issue: 1
Pages: 13
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16546298 | J:128236
First Author: Bjelik A
Year: 2006
Journal: Neurochem Int
Title: Human apoB overexpression and a high-cholesterol diet differently modify the brain APP metabolism in the transgenic mouse model of atherosclerosis.
Volume: 49
Issue: 4
Pages: 393-400
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Publication
37850918 | J:348873
First Author: Ueda S
Year: 2023
Journal: FASEB J
Title: Acute inhibition of AMPA receptors by perampanel reduces amyloid β-protein levels by suppressing β-cleavage of APP in Alzheimer's disease models.
Volume: 37
Issue: 11
Pages: e23252
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Publication
20212127 | J:158688
First Author: Seshadri S
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Disrupted-in-Schizophrenia-1 expression is regulated by beta-site amyloid precursor protein cleaving enzyme-1-neuregulin cascade.
Volume: 107
Issue: 12
Pages: 5622-7
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Publication
22728099 | J:192517
 
First Author: Marques SC
Year: 2012
Journal: Neuroscience
Title: Epigenetic regulation of BACE1 in Alzheimer's disease patients and in transgenic mice.
Volume: 220
Pages: 256-66
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22717236 | J:194436
First Author: Guo C
Year: 2013
Journal: Neurobiol Aging
Title: Intranasal deferoxamine reverses iron-induced memory deficits and inhibits amyloidogenic APP processing in a transgenic mouse model of Alzheimer's disease.
Volume: 34
Issue: 2
Pages: 562-75
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16901557 | J:112413
First Author: Zhang L
Year: 2006
Journal: Behav Brain Res
Title: Learning-memory deficit with aging in APP transgenic mice of Alzheimer's disease and intervention by using tetrahydroxystilbene glucoside.
Volume: 173
Issue: 2
Pages: 246-54
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22958226 | J:207645
First Author: Wang FH
Year: 2012
Journal: Eur J Neurosci
Title: Decreased axonal transport rates in the Tg2576 APP transgenic mouse: improvement with the gamma-secretase inhibitor MRK-560 as detected by manganese-enhanced MRI.
Volume: 36
Issue: 9
Pages: 3165-72
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Publication
23071606 | J:192092
First Author: Rabinovich-Nikitin I
Year: 2012
Journal: PLoS One
Title: Beneficial effect of antibodies against β- secretase cleavage site of APP on Alzheimer's-like pathology in triple-transgenic mice.
Volume: 7
Issue: 10
Pages: e46650
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Publication
18547679 | J:159592
First Author: Ye H
Year: 2010
Journal: Neurobiol Aging
Title: Activation of large-conductance Ca(2+)-activated K(+) channels depresses basal synaptic transmission in the hippocampal CA1 area in APP (swe/ind) TgCRND8 mice.
Volume: 31
Issue: 4
Pages: 591-604
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1322500 | J:1586
First Author: Kyriakis JM
Year: 1992
Journal: Nature
Title: Raf-1 activates MAP kinase-kinase.
Volume: 358
Issue: 6385
Pages: 417-21
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29038051 | J:255655
First Author: Nam KN
Year: 2018
Journal: Biochim Biophys Acta
Title: Integrated approach reveals diet, APOE genotype and sex affect immune response in APP mice.
Volume: 1864
Issue: 1
Pages: 152-161
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23748737 | J:225054
 
First Author: Pozueta J
Year: 2013
Journal: Nat Commun
Title: Caspase-2 is required for dendritic spine and behavioural alterations in J20 APP transgenic mice.
Volume: 4
Pages: 1939
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Publication
25027328 | J:216231
First Author: He P
Year: 2014
Journal: Hum Mol Genet
Title: Deficiency of patched 1-induced Gli1 signal transduction results in astrogenesis in Swedish mutated APP transgenic mice.
Volume: 23
Issue: 24
Pages: 6512-27
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23273572 | J:203375
First Author: Dassie E
Year: 2013
Journal: Neurobiol Aging
Title: Focal expression of adeno-associated viral-mutant tau induces widespread impairment in an APP mouse model.
Volume: 34
Issue: 5
Pages: 1355-68
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14687544 | J:87150
First Author: Leissring MA
Year: 2003
Journal: Neuron
Title: Enhanced proteolysis of beta-amyloid in APP transgenic mice prevents plaque formation, secondary pathology, and premature death.
Volume: 40
Issue: 6
Pages: 1087-93
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Publication
23773908 | J:202110
 
First Author: Oue H
Year: 2013
Journal: Behav Brain Res
Title: Tooth loss induces memory impairment and neuronal cell loss in APP transgenic mice.
Volume: 252
Pages: 318-25
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Publication
35675410 | J:341501
First Author: Chocron ES
Year: 2022
Journal: Sci Adv
Title: Genetic and pharmacologic proteasome augmentation ameliorates Alzheimer's-like pathology in mouse and fly APP overexpression models.
Volume: 8
Issue: 23
Pages: eabk2252
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Publication
31969805 | J:309743
 
First Author: Shen Y
Year: 2019
Journal: Front Cell Neurosci
Title: Activation of Mitochondrial Unfolded Protein Response in SHSY5Y Expressing APP Cells and APP/PS1 Mice.
Volume: 13
Pages: 568
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Publication
22294787 | J:237165
First Author: Lakshmana MK
Year: 2012
Journal: FASEB J
Title: Role of RanBP9 on amyloidogenic processing of APP and synaptic protein levels in the mouse brain.
Volume: 26
Issue: 5
Pages: 2072-83
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Publication
19657023 | J:252040
First Author: Tampellini D
Year: 2009
Journal: J Neurosci
Title: Synaptic activity reduces intraneuronal Abeta, promotes APP transport to synapses, and protects against Abeta-related synaptic alterations.
Volume: 29
Issue: 31
Pages: 9704-13
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Publication
7499323 | J:100980
First Author: Rockenstein EM
Year: 1995
Journal: J Biol Chem
Title: Levels and alternative splicing of amyloid beta protein precursor (APP) transcripts in brains of APP transgenic mice and humans with Alzheimer's disease.
Volume: 270
Issue: 47
Pages: 28257-67
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22492996 | J:184612
First Author: Mao P
Year: 2012
Journal: Hum Mol Genet
Title: Mitochondria-targeted catalase reduces abnormal APP processing, amyloid β production and BACE1 in a mouse model of Alzheimer's disease: implications for neuroprotection and lifespan extension.
Volume: 21
Issue: 13
Pages: 2973-90
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Publication
31164420 | J:279242
First Author: Bahn G
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: NRF2/ARE pathway negatively regulates BACE1 expression and ameliorates cognitive deficits in mouse Alzheimer's models.
Volume: 116
Issue: 25
Pages: 12516-12523
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Publication
15262269 | J:131666
First Author: Szapacs ME
Year: 2004
Journal: Neurobiol Dis
Title: Late onset loss of hippocampal 5-HT and NE is accompanied by increases in BDNF protein expression in mice co-expressing mutant APP and PS1.
Volume: 16
Issue: 3
Pages: 572-80
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Publication
18680556 | J:140135
First Author: Chen L
Year: 2008
Journal: J Neurochem
Title: Lipid peroxidation up-regulates BACE1 expression in vivo: a possible early event of amyloidogenesis in Alzheimer's disease.
Volume: 107
Issue: 1
Pages: 197-207
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Publication
20080541 | J:156746
First Author: Jiang Y
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Alzheimer's-related endosome dysfunction in Down syndrome is Abeta-independent but requires APP and is reversed by BACE-1 inhibition.
Volume: 107
Issue: 4
Pages: 1630-5
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Publication
33208500 | J:338513
 
First Author: Lomoio S
Year: 2020
Journal: Sci Transl Med
Title: Gga3 deletion and a GGA3 rare variant associated with late onset Alzheimer's disease trigger BACE1 accumulation in axonal swellings.
Volume: 12
Issue: 570
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Publication
15380017 | J:101290
First Author: Domínguez-del-Toro E
Year: 2004
Journal: Eur J Neurosci
Title: An in vitro and in vivo study of early deficits in associative learning in transgenic mice that over-express a mutant form of human APP associated with Alzheimer's disease.
Volume: 20
Issue: 7
Pages: 1945-52
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Publication
31741224 | J:319510
First Author: Kim N
Year: 2020
Journal: Neurotherapeutics
Title: Picrorhiza kurroa Prevents Memory Deficits by Inhibiting NLRP3 Inflammasome Activation and BACE1 Expression in 5xFAD Mice.
Volume: 17
Issue: 1
Pages: 189-199
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Publication
27734846 | J:263434
 
First Author: Strecker P
Year: 2016
Journal: Sci Rep
Title: FE65 and FE65L1 share common synaptic functions and genetically interact with the APP family in neuromuscular junction formation.
Volume: 6
Pages: 25652
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Publication
25887956 | J:323141
 
First Author: Liao F
Year: 2015
Journal: Mol Neurodegener
Title: Effects of CD2-associated protein deficiency on amyloid-β in neuroblastoma cells and in an APP transgenic mouse model.
Volume: 10
Pages: 12
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Publication
23022919 | J:196994
 
First Author: Beauquis J
Year: 2013
Journal: Exp Neurol
Title: Environmental enrichment prevents astroglial pathological changes in the hippocampus of APP transgenic mice, model of Alzheimer's disease.
Volume: 239
Pages: 28-37
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Publication
32950104 | J:352668
First Author: Liu YC
Year: 2021
Journal: Mol Ther
Title: Melatonin Induction of APP Intracellular Domain 50 SUMOylation Alleviates AD through Enhanced Transcriptional Activation and Aβ Degradation.
Volume: 29
Issue: 1
Pages: 376-395
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Publication
19272356 | J:156577
 
First Author: Maheswaran S
Year: 2009
Journal: Brain Res
Title: Longitudinal regional brain volume changes quantified in normal aging and Alzheimer's APP x PS1 mice using MRI.
Volume: 1270
Pages: 19-32
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Publication
26251449 | J:227027
First Author: Jäckle F
Year: 2015
Journal: Biochem J
Title: Metalloprotease meprin β is activated by transmembrane serine protease matriptase-2 at the cell surface thereby enhancing APP shedding.
Volume: 470
Issue: 1
Pages: 91-103
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Publication
34478848 | J:312976
 
First Author: Yanguas-Casás N
Year: 2021
Journal: Neurobiol Dis
Title: High-fat diet alters stress behavior, inflammatory parameters and gut microbiota in Tg APP mice in a sex-specific manner.
Volume: 159
Pages: 105495
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Publication
21825135 | J:175989
First Author: Sannerud R
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: ADP ribosylation factor 6 (ARF6) controls amyloid precursor protein (APP) processing by mediating the endosomal sorting of BACE1.
Volume: 108
Issue: 34
Pages: E559-68
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Publication
36370135 | J:351610
First Author: Chen XQ
Year: 2023
Journal: Alzheimers Dement
Title: Reduced synaptic proteins and SNARE complexes in Down syndrome with Alzheimer's disease and the Dp16 mouse Down syndrome model: Impact of APP gene dose.
Volume: 19
Issue: 5
Pages: 2095-2116
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