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Search results 1401 to 1500 out of 1785 for Cx3cr1

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0.202s

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Category: Publication
Type Details Score
Publication
First Author: Gu N
Year: 2016
Journal: Cell Rep
Title: Spinal Microgliosis Due to Resident Microglial Proliferation Is Required for Pain Hypersensitivity after Peripheral Nerve Injury.
Volume: 16
Issue: 3
Pages: 605-14
Publication  
First Author: Asano K
Year: 2015
Journal: Nat Commun
Title: Intestinal CD169(+) macrophages initiate mucosal inflammation by secreting CCL8 that recruits inflammatory monocytes.
Volume: 6
Pages: 7802
Publication
First Author: Smolders SM
Year: 2017
Journal: Glia
Title: Age-specific function of α5β1 integrin in microglial migration during early colonization of the developing mouse cortex.
Volume: 65
Issue: 7
Pages: 1072-1088
Publication
First Author: Zhang J
Year: 2021
Journal: Nature
Title: In situ mapping identifies distinct vascular niches for myelopoiesis.
Volume: 590
Issue: 7846
Pages: 457-462
Publication
First Author: Xie M
Year: 2022
Journal: Nat Neurosci
Title: TREM2 interacts with TDP-43 and mediates microglial neuroprotection against TDP-43-related neurodegeneration.
Volume: 25
Issue: 1
Pages: 26-38
Publication
First Author: Flores-Toro JA
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: CCR2 inhibition reduces tumor myeloid cells and unmasks a checkpoint inhibitor effect to slow progression of resistant murine gliomas.
Volume: 117
Issue: 2
Pages: 1129-1138
Publication
First Author: Yamasaki R
Year: 2016
Journal: J Neurosci
Title: Allergic Inflammation Leads to Neuropathic Pain via Glial Cell Activation.
Volume: 36
Issue: 47
Pages: 11929-11945
Publication
First Author: Lin HB
Year: 2024
Journal: J Am Heart Assoc
Title: Monocyte-Derived Macrophages Aggravate Cardiac Dysfunction After Ischemic Stroke in Mice.
Volume: 13
Issue: 9
Pages: e034731
Publication
First Author: Eyo UB
Year: 2018
Journal: Cell Rep
Title: P2Y12R-Dependent Translocation Mechanisms Gate the Changing Microglial Landscape.
Volume: 23
Issue: 4
Pages: 959-966
Publication
First Author: von Roemeling CA
Year: 2024
Journal: Nat Commun
Title: Adeno-associated virus delivered CXCL9 sensitizes glioblastoma to anti-PD-1 immune checkpoint blockade.
Volume: 15
Issue: 1
Pages: 5871
Publication
First Author: Fujita Y
Year: 2020
Journal: Cell Rep
Title: Netrin-G1 Regulates Microglial Accumulation along Axons and Supports the Survival of Layer V Neurons in the Postnatal Mouse Brain.
Volume: 31
Issue: 4
Pages: 107580
Publication
First Author: Hattori Y
Year: 2022
Journal: J Neurosci
Title: Embryonic Pericytes Promote Microglial Homeostasis and Their Effects on Neural Progenitors in the Developing Cerebral Cortex.
Volume: 42
Issue: 3
Pages: 362-376
Publication
First Author: Eyo UB
Year: 2021
Journal: Cell Rep
Title: Microglia provide structural resolution to injured dendrites after severe seizures.
Volume: 35
Issue: 5
Pages: 109080
Publication
First Author: Niu J
Year: 2019
Journal: Nat Neurosci
Title: Aberrant oligodendroglial-vascular interactions disrupt the blood-brain barrier, triggering CNS inflammation.
Volume: 22
Issue: 5
Pages: 709-718
Publication
First Author: Luche H
Year: 2011
Journal: Eur J Immunol
Title: The earliest intrathymic precursors of CD8α(+) thymic dendritic cells correspond to myeloid-type double-negative 1c cells.
Volume: 41
Issue: 8
Pages: 2165-75
Publication
First Author: Satoh-Takayama N
Year: 2014
Journal: Immunity
Title: The chemokine receptor CXCR6 controls the functional topography of interleukin-22 producing intestinal innate lymphoid cells.
Volume: 41
Issue: 5
Pages: 776-88
Publication
First Author: Locatelli G
Year: 2018
Journal: Nat Neurosci
Title: Mononuclear phagocytes locally specify and adapt their phenotype in a multiple sclerosis model.
Volume: 21
Issue: 9
Pages: 1196-1208
Publication
First Author: Bertrand JY
Year: 2005
Journal: Blood
Title: Three pathways to mature macrophages in the early mouse yolk sac.
Volume: 106
Issue: 9
Pages: 3004-11
Publication
First Author: Ardeljan D
Year: 2014
Journal: PLoS One
Title: Interleukin-17 retinotoxicity is prevented by gene transfer of a soluble interleukin-17 receptor acting as a cytokine blocker: implications for age-related macular degeneration.
Volume: 9
Issue: 4
Pages: e95900
Publication
First Author: Sherafat A
Year: 2021
Journal: Nat Commun
Title: Microglial neuropilin-1 promotes oligodendrocyte expansion during development and remyelination by trans-activating platelet-derived growth factor receptor.
Volume: 12
Issue: 1
Pages: 2265
Publication
First Author: Jiang S
Year: 2021
Journal: Cell Rep
Title: Proteopathic tau primes and activates interleukin-1β via myeloid-cell-specific MyD88- and NLRP3-ASC-inflammasome pathway.
Volume: 36
Issue: 12
Pages: 109720
Publication  
First Author: Ma C
Year: 2021
Journal: J Exp Med
Title: AIM2 controls microglial inflammation to prevent experimental autoimmune encephalomyelitis.
Volume: 218
Issue: 5
Publication
First Author: Wang X
Year: 2024
Journal: Alzheimers Res Ther
Title: Intermittent hypoxia training enhances Aβ endocytosis by plaque associated microglia via VPS35-dependent TREM2 recycling in murine Alzheimer's disease.
Volume: 16
Issue: 1
Pages: 121
Publication
First Author: Viladomiu M
Year: 2022
Journal: Cell Rep
Title: Agr2-associated ER stress promotes adherent-invasive E. coli dysbiosis and triggers CD103(+) dendritic cell IL-23-dependent ileocolitis.
Volume: 41
Issue: 7
Pages: 111637
Publication
First Author: Viladomiu M
Year: 2021
Journal: Cell Host Microbe
Title: Adherent-invasive E. coli metabolism of propanediol in Crohn's disease regulates phagocytes to drive intestinal inflammation.
Volume: 29
Issue: 4
Pages: 607-619.e8
Publication
First Author: Drummond RA
Year: 2019
Journal: Nat Immunol
Title: CARD9+ microglia promote antifungal immunity via IL-1β- and CXCL1-mediated neutrophil recruitment.
Volume: 20
Issue: 5
Pages: 559-570
Publication
First Author: Hu J
Year: 2023
Journal: Neuron
Title: Microglial Piezo1 senses Aβ fibril stiffness to restrict Alzheimer's disease.
Volume: 111
Issue: 1
Pages: 15-29.e8
Publication
First Author: Seidman JS
Year: 2020
Journal: Immunity
Title: Niche-Specific Reprogramming of Epigenetic Landscapes Drives Myeloid Cell Diversity in Nonalcoholic Steatohepatitis.
Volume: 52
Issue: 6
Pages: 1057-1074.e7
Publication  
First Author: Rosin JM
Year: 2022
Journal: Front Neurosci
Title: Gestational Bisphenol A Exposure Impacts Embryonic Hypothalamic Microglia Numbers, Ramification, and Phagocytic Cups.
Volume: 16
Pages: 830399
Publication
First Author: Guo DH
Year: 2020
Journal: J Clin Invest
Title: Visceral adipose NLRP3 impairs cognition in obesity via IL-1R1 on CX3CR1+ cells.
Volume: 130
Issue: 4
Pages: 1961-1976
Publication  
First Author: Alves M
Year: 2024
Journal: Brain Behav Immun
Title: Opposing effects of the purinergic P2X7 receptor on seizures in neurons and microglia in male mice.
Volume: 120
Pages: 121-140
Publication
First Author: Liao Y
Year: 2020
Journal: Theranostics
Title: HDAC3 inhibition ameliorates ischemia/reperfusion-induced brain injury by regulating the microglial cGAS-STING pathway.
Volume: 10
Issue: 21
Pages: 9644-9662
Publication
First Author: Lu J
Year: 2022
Journal: J Neuroinflammation
Title: A breakdown in microglial metabolic reprogramming causes internalization dysfunction of α-synuclein in a mouse model of Parkinson's disease.
Volume: 19
Issue: 1
Pages: 113
Publication    
First Author: Green JP
Year: 2020
Journal: Elife
Title: LRRC8A is essential for hypotonicity-, but not for DAMP-induced NLRP3 inflammasome activation.
Volume: 9
Publication  
First Author: Li X
Year: 2021
Journal: Sci Adv
Title: Annexin-A1 SUMOylation regulates microglial polarization after cerebral ischemia by modulating IKKα stability via selective autophagy.
Volume: 7
Issue: 4
Publication
First Author: Williamson AE
Year: 2024
Journal: Nat Commun
Title: Discovery of an embryonically derived bipotent population of endothelial-macrophage progenitor cells in postnatal aorta.
Volume: 15
Issue: 1
Pages: 7097
Publication
First Author: Luo J
Year: 2018
Journal: J Allergy Clin Immunol
Title: Transient receptor potential vanilloid 4-expressing macrophages and keratinocytes contribute differentially to allergic and nonallergic chronic itch.
Volume: 141
Issue: 2
Pages: 608-619.e7
Publication
First Author: Li X
Year: 2024
Journal: Diabetes
Title: A Neuron-Mast Cell Axis Regulates Skin Microcirculation in Diabetes.
Volume: 73
Issue: 10
Pages: 1728-1741
Publication  
First Author: Almeida FF
Year: 2015
Journal: Sci Rep
Title: Identification of a novel lymphoid population in the murine epidermis.
Volume: 5
Pages: 12554
Publication  
First Author: Van Deren DA
Year: 2022
Journal: Development
Title: Defining the Hoxb8 cell lineage during murine definitive hematopoiesis.
Volume: 149
Issue: 8
Publication
First Author: Tran S
Year: 2020
Journal: Immunity
Title: Impaired Kupffer Cell Self-Renewal Alters the Liver Response to Lipid Overload during Non-alcoholic Steatohepatitis.
Volume: 53
Issue: 3
Pages: 627-640.e5
Publication
First Author: Juban G
Year: 2018
Journal: Cell Rep
Title: AMPK Activation Regulates LTBP4-Dependent TGF-β1 Secretion by Pro-inflammatory Macrophages and Controls Fibrosis in Duchenne Muscular Dystrophy.
Volume: 25
Issue: 8
Pages: 2163-2176.e6
Publication
First Author: Hoeffel G
Year: 2012
Journal: J Exp Med
Title: Adult Langerhans cells derive predominantly from embryonic fetal liver monocytes with a minor contribution of yolk sac-derived macrophages.
Volume: 209
Issue: 6
Pages: 1167-81
Publication
First Author: Percin GI
Year: 2018
Journal: Nat Commun
Title: CSF1R regulates the dendritic cell pool size in adult mice via embryo-derived tissue-resident macrophages.
Volume: 9
Issue: 1
Pages: 5279
Publication
First Author: Masse GX
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Gamma c cytokines condition the progressive differentiation of CD4+ T cells.
Volume: 104
Issue: 39
Pages: 15442-7
Publication
First Author: Sung CYW
Year: 2024
Journal: Sci Adv
Title: Macrophage depletion protects against cisplatin-induced ototoxicity and nephrotoxicity.
Volume: 10
Issue: 30
Pages: eadk9878
Publication
First Author: Zhao L
Year: 2015
Journal: EMBO Mol Med
Title: Microglial phagocytosis of living photoreceptors contributes to inherited retinal degeneration.
Volume: 7
Issue: 9
Pages: 1179-97
Publication
First Author: Di Pietro C
Year: 2022
Journal: Exp Mol Med
Title: Recruitment of monocytes primed to express heme oxygenase-1 ameliorates pathological lung inflammation in cystic fibrosis.
Volume: 54
Issue: 5
Pages: 639-652
Publication
First Author: Lau CM
Year: 2016
Journal: J Exp Med
Title: Leukemia-associated activating mutation of Flt3 expands dendritic cells and alters T cell responses.
Volume: 213
Issue: 3
Pages: 415-31
Publication
First Author: Dähling S
Year: 2022
Journal: Immunity
Title: Type 1 conventional dendritic cells maintain and guide the differentiation of precursors of exhausted T cells in distinct cellular niches.
Volume: 55
Issue: 4
Pages: 656-670.e8
Publication
First Author: Cai XT
Year: 2024
Journal: Cell Rep
Title: IL-4-induced SOX9 confers lineage plasticity to aged adult lung stem cells.
Volume: 43
Issue: 8
Pages: 114569
Publication
First Author: Herz J
Year: 2021
Journal: Neuron
Title: GABAergic neuronal IL-4R mediates T cell effect on memory.
Volume: 109
Issue: 22
Pages: 3609-3618.e9
Publication
First Author: Lim HY
Year: 2018
Journal: Immunity
Title: Hyaluronan Receptor LYVE-1-Expressing Macrophages Maintain Arterial Tone through Hyaluronan-Mediated Regulation of Smooth Muscle Cell Collagen.
Volume: 49
Issue: 2
Pages: 326-341.e7
Publication
First Author: Park I
Year: 2022
Journal: Nat Commun
Title: C-type lectin receptor CLEC4A2 promotes tissue adaptation of macrophages and protects against atherosclerosis.
Volume: 13
Issue: 1
Pages: 215
Publication
First Author: Pekayvaz K
Year: 2023
Journal: Immunity
Title: Mural cell-derived chemokines provide a protective niche to safeguard vascular macrophages and limit chronic inflammation.
Volume: 56
Issue: 10
Pages: 2325-2341.e15
Publication
First Author: Williams JW
Year: 2017
Journal: Circ Res
Title: Thermoneutrality but Not UCP1 Deficiency Suppresses Monocyte Mobilization Into Blood.
Volume: 121
Issue: 6
Pages: 662-676
Publication
First Author: Rahman K
Year: 2017
Journal: J Clin Invest
Title: Inflammatory Ly6Chi monocytes and their conversion to M2 macrophages drive atherosclerosis regression.
Volume: 127
Issue: 8
Pages: 2904-2915
Publication
First Author: Safaiyan S
Year: 2021
Journal: Neuron
Title: White matter aging drives microglial diversity.
Volume: 109
Issue: 7
Pages: 1100-1117.e10
Publication
First Author: Anastasaki C
Year: 2022
Journal: Acta Neuropathol Commun
Title: Human induced pluripotent stem cell engineering establishes a humanized mouse platform for pediatric low-grade glioma modeling.
Volume: 10
Issue: 1
Pages: 120
Publication
First Author: Chen Z
Year: 2023
Journal: Nat Commun
Title: Monocyte depletion enhances neutrophil influx and proneural to mesenchymal transition in glioblastoma.
Volume: 14
Issue: 1
Pages: 1839
Publication
First Author: Yang W
Year: 2019
Journal: Nat Commun
Title: Neutrophils promote the development of reparative macrophages mediated by ROS to orchestrate liver repair.
Volume: 10
Issue: 1
Pages: 1076
Publication
First Author: Harding JS
Year: 2019
Journal: Cell Rep
Title: VEGF-A from Granuloma Macrophages Regulates Granulomatous Inflammation by a Non-angiogenic Pathway during Mycobacterial Infection.
Volume: 27
Issue: 7
Pages: 2119-2131.e6
Publication
First Author: Xu ZX
Year: 2020
Journal: Nat Commun
Title: Elevated protein synthesis in microglia causes autism-like synaptic and behavioral aberrations.
Volume: 11
Issue: 1
Pages: 1797
Publication
First Author: Pasquevich KA
Year: 2015
Journal: Eur J Immunol
Title: Innate immune system favors emergency monopoiesis at the expense of DC-differentiation to control systemic bacterial infection in mice.
Volume: 45
Issue: 10
Pages: 2821-33
Publication
First Author: Kim HJ
Year: 2022
Journal: Nat Commun
Title: Blood monocyte-derived CD169+ macrophages contribute to antitumor immunity against glioblastoma.
Volume: 13
Issue: 1
Pages: 6211
Publication    
First Author: Tang XZ
Year: 2022
Journal: Elife
Title: Bronchus-associated macrophages efficiently capture and present soluble inhaled antigens and are capable of local Th2 cell activation.
Volume: 11
Publication
First Author: Liew PX
Year: 2017
Journal: Immunity
Title: iNKT Cells Orchestrate a Switch from Inflammation to Resolution of Sterile Liver Injury.
Volume: 47
Issue: 4
Pages: 752-765.e5
Publication
First Author: Choi BR
Year: 2023
Journal: Nat Immunol
Title: Monocyte-derived IL-6 programs microglia to rebuild damaged brain vasculature.
Volume: 24
Issue: 7
Pages: 1110-1123
Publication
First Author: Klawonn AM
Year: 2021
Journal: Immunity
Title: Microglial activation elicits a negative affective state through prostaglandin-mediated modulation of striatal neurons.
Volume: 54
Issue: 2
Pages: 225-234.e6
Publication
First Author: Hu Z
Year: 2020
Journal: Cell Rep
Title: CNTF-STAT3-IL-6 Axis Mediates Neuroinflammatory Cascade across Schwann Cell-Neuron-Microglia.
Volume: 31
Issue: 7
Pages: 107657
Publication
First Author: Garré JM
Year: 2017
Journal: Nat Med
Title: CX3CR1+ monocytes modulate learning and learning-dependent dendritic spine remodeling via TNF-α.
Volume: 23
Issue: 6
Pages: 714-722
Publication
First Author: Daussy C
Year: 2014
Journal: J Exp Med
Title: T-bet and Eomes instruct the development of two distinct natural killer cell lineages in the liver and in the bone marrow.
Volume: 211
Issue: 3
Pages: 563-77
Publication
First Author: Zegarra Ruiz DF
Year: 2022
Journal: Gut Microbes
Title: Microbiota manipulation to increase macrophage IL-10 improves colitis and limits colitis-associated colorectal cancer.
Volume: 14
Issue: 1
Pages: 2119054
Publication
First Author: McDole JR
Year: 2012
Journal: Nature
Title: Goblet cells deliver luminal antigen to CD103+ dendritic cells in the small intestine.
Volume: 483
Issue: 7389
Pages: 345-9
Publication
First Author: Chow A
Year: 2011
Journal: J Exp Med
Title: Bone marrow CD169+ macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche.
Volume: 208
Issue: 2
Pages: 261-71
Publication
First Author: Krueger PD
Year: 2021
Journal: Immunity
Title: Two sequential activation modules control the differentiation of protective T helper-1 (Th1) cells.
Volume: 54
Issue: 4
Pages: 687-701.e4
Publication  
First Author: Park SM
Year: 2019
Journal: Commun Biol
Title: T cell fate following Salmonella infection is determined by a STING-IRF1 signaling axis in mice.
Volume: 2
Pages: 464
Publication
First Author: Yun TJ
Year: 2016
Journal: Cell Metab
Title: Indoleamine 2,3-Dioxygenase-Expressing Aortic Plasmacytoid Dendritic Cells Protect against Atherosclerosis by Induction of Regulatory T Cells.
Volume: 23
Issue: 5
Pages: 852-66
Publication
First Author: Izumi G
Year: 2021
Journal: Nat Commun
Title: CD11b+ lung dendritic cells at different stages of maturation induce Th17 or Th2 differentiation.
Volume: 12
Issue: 1
Pages: 5029
Publication
First Author: Chéret C
Year: 2008
Journal: J Neurosci
Title: Neurotoxic activation of microglia is promoted by a nox1-dependent NADPH oxidase.
Volume: 28
Issue: 46
Pages: 12039-51
Publication  
First Author: Liu G
Year: 2021
Journal: mBio
Title: IL-27 Negatively Regulates Tip-DC Development during Infection.
Volume: 12
Issue: 1
Publication
First Author: Gan Y
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Ischemic neurons recruit natural killer cells that accelerate brain infarction.
Volume: 111
Issue: 7
Pages: 2704-9
Publication
First Author: Oberbarnscheidt MH
Year: 2014
Journal: J Clin Invest
Title: Non-self recognition by monocytes initiates allograft rejection.
Volume: 124
Issue: 8
Pages: 3579-89
Publication
First Author: Zhang Q
Year: 2022
Journal: Nat Commun
Title: TH17 cells promote CNS inflammation by sensing danger signals via Mincle.
Volume: 13
Issue: 1
Pages: 2406
Publication
First Author: Torow N
Year: 2023
Journal: Immunity
Title: M cell maturation and cDC activation determine the onset of adaptive immune priming in the neonatal Peyer's patch.
Volume: 56
Issue: 6
Pages: 1220-1238.e7
Publication
First Author: Masle-Farquhar E
Year: 2022
Journal: Immunity
Title: STAT3 gain-of-function mutations connect leukemia with autoimmune disease by pathological NKG2D(hi) CD8(+) T cell dysregulation and accumulation.
Volume: 55
Issue: 12
Pages: 2386-2404.e8
Publication
First Author: Shi L
Year: 2021
Journal: Immunity
Title: Treg cell-derived osteopontin promotes microglia-mediated white matter repair after ischemic stroke.
Volume: 54
Issue: 7
Pages: 1527-1542.e8
Publication
First Author: Kohno H
Year: 2014
Journal: J Immunol
Title: CCL3 production by microglial cells modulates disease severity in murine models of retinal degeneration.
Volume: 192
Issue: 8
Pages: 3816-27
Publication
First Author: Ross JL
Year: 2024
Journal: Immunity
Title: Microglia and monocyte-derived macrophages drive progression of pediatric high-grade gliomas and are transcriptionally shaped by histone mutations.
Volume: 57
Issue: 11
Pages: 2669-2687.e6
Publication    
First Author: Anderson SR
Year: 2022
Journal: Elife
Title: Neuronal apoptosis drives remodeling states of microglia and shifts in survival pathway dependence.
Volume: 11
Publication
First Author: Berta T
Year: 2014
Journal: J Clin Invest
Title: Extracellular caspase-6 drives murine inflammatory pain via microglial TNF-α secretion.
Volume: 124
Issue: 3
Pages: 1173-86
Publication
First Author: Wang Q
Year: 2021
Journal: Nature
Title: IL-27 signalling promotes adipocyte thermogenesis and energy expenditure.
Volume: 600
Issue: 7888
Pages: 314-318
Publication
First Author: De Boeck A
Year: 2020
Journal: Nat Commun
Title: Glioma-derived IL-33 orchestrates an inflammatory brain tumor microenvironment that accelerates glioma progression.
Volume: 11
Issue: 1
Pages: 4997
Publication
First Author: Chen Z
Year: 2020
Journal: Glia
Title: Genetic driver mutations introduced in identical cell-of-origin in murine glioblastoma reveal distinct immune landscapes but similar response to checkpoint blockade.
Volume: 68
Issue: 10
Pages: 2148-2166
Publication
First Author: Kälin RE
Year: 2021
Journal: Cell Syst
Title: TAMEP are brain tumor parenchymal cells controlling neoplastic angiogenesis and progression.
Volume: 12
Issue: 3
Pages: 248-262.e7
Publication
First Author: Chen Z
Year: 2017
Journal: Cancer Res
Title: Cellular and Molecular Identity of Tumor-Associated Macrophages in Glioblastoma.
Volume: 77
Issue: 9
Pages: 2266-2278
Publication
First Author: Dmitrieva-Posocco O
Year: 2019
Journal: Immunity
Title: Cell-Type-Specific Responses to Interleukin-1 Control Microbial Invasion and Tumor-Elicited Inflammation in Colorectal Cancer.
Volume: 50
Issue: 1
Pages: 166-180.e7
Publication
First Author: Mesa KR
Year: 2015
Journal: Nature
Title: Niche-induced cell death and epithelial phagocytosis regulate hair follicle stem cell pool.
Volume: 522
Issue: 7554
Pages: 94-7
Publication
First Author: Longman RS
Year: 2014
Journal: J Exp Med
Title: CX₃CR1⁺ mononuclear phagocytes support colitis-associated innate lymphoid cell production of IL-22.
Volume: 211
Issue: 8
Pages: 1571-83
Publication
First Author: Kawakami T
Year: 2013
Journal: J Immunol
Title: Resident renal mononuclear phagocytes comprise five discrete populations with distinct phenotypes and functions.
Volume: 191
Issue: 6
Pages: 3358-72