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Search results 1401 to 1500 out of 2570 for Kras

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Category: Publication
Type Details Score
Publication
First Author: Barilla RM
Year: 2019
Journal: Nat Commun
Title: Specialized dendritic cells induce tumor-promoting IL-10+IL-17+ FoxP3neg regulatory CD4+ T cells in pancreatic carcinoma.
Volume: 10
Issue: 1
Pages: 1424
Publication
First Author: Johnson L
Year: 1997
Journal: Genes Dev
Title: K-ras is an essential gene in the mouse with partial functional overlap with N-ras.
Volume: 11
Issue: 19
Pages: 2468-81
Publication
First Author: Benitz S
Year: 2016
Journal: Oncotarget
Title: Polycomb repressor complex 1 promotes gene silencing through H2AK119 mono-ubiquitination in acinar-to-ductal metaplasia and pancreatic cancer cells.
Volume: 7
Issue: 10
Pages: 11424-33
Publication
First Author: Neuß T
Year: 2024
Journal: Cancer Res
Title: Metabolic Reprogramming Is an Initial Step in Pancreatic Carcinogenesis That Can Be Targeted to Inhibit Acinar-to-Ductal Metaplasia.
Volume: 84
Issue: 14
Pages: 2297-2312
Publication
First Author: Costa RM
Year: 2002
Journal: Nature
Title: Mechanism for the learning deficits in a mouse model of neurofibromatosis type 1.
Volume: 415
Issue: 6871
Pages: 526-30
Publication
First Author: Hari P
Year: 2019
Journal: Sci Adv
Title: The innate immune sensor Toll-like receptor 2 controls the senescence-associated secretory phenotype.
Volume: 5
Issue: 6
Pages: eaaw0254
Publication
First Author: Lampson BL
Year: 2012
Journal: Cancer Res
Title: Targeting eNOS in pancreatic cancer.
Volume: 72
Issue: 17
Pages: 4472-82
Publication
First Author: Chan IS
Year: 2012
Journal: Cancer Res
Title: Paracrine Hedgehog signaling drives metabolic changes in hepatocellular carcinoma.
Volume: 72
Issue: 24
Pages: 6344-50
Publication
First Author: Zaytouni T
Year: 2017
Journal: Nat Commun
Title: Critical role for arginase 2 in obesity-associated pancreatic cancer.
Volume: 8
Issue: 1
Pages: 242
Publication  
First Author: Fitzgerald B
Year: 2021
Journal: Cell Rep Methods
Title: A mouse model for the study of anti-tumor T cell responses in Kras-driven lung adenocarcinoma.
Volume: 1
Issue: 5
Publication
First Author: Kurz E
Year: 2022
Journal: Cancer Cell
Title: Exercise-induced engagement of the IL-15/IL-15Rα axis promotes anti-tumor immunity in pancreatic cancer.
Volume: 40
Issue: 7
Pages: 720-737.e5
Publication
First Author: Dasgupta B
Year: 2005
Journal: Cancer Res
Title: Cerebrospinal fluid proteomic analysis reveals dysregulation of methionine aminopeptidase-2 expression in human and mouse neurofibromatosis 1-associated glioma.
Volume: 65
Issue: 21
Pages: 9843-50
Publication
First Author: Anastasaki C
Year: 2014
Journal: Hum Mol Genet
Title: Neuronal NF1/RAS regulation of cyclic AMP requires atypical PKC activation.
Volume: 23
Issue: 25
Pages: 6712-21
Publication
First Author: Andricovich J
Year: 2018
Journal: Cancer Cell
Title: Loss of KDM6A Activates Super-Enhancers to Induce Gender-Specific Squamous-like Pancreatic Cancer and Confers Sensitivity to BET Inhibitors.
Volume: 33
Issue: 3
Pages: 512-526.e8
Publication
First Author: Gregorian C
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: PTEN dosage is essential for neurofibroma development and malignant transformation.
Volume: 106
Issue: 46
Pages: 19479-84
Publication
First Author: Su W
Year: 2007
Journal: Glia
Title: Mice with GFAP-targeted loss of neurofibromin demonstrate increased axonal MET expression with aging.
Volume: 55
Issue: 7
Pages: 723-33
Publication
First Author: Dovey JS
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Bmi1 is critical for lung tumorigenesis and bronchioalveolar stem cell expansion.
Volume: 105
Issue: 33
Pages: 11857-62
Publication
First Author: Nakamura K
Year: 2008
Journal: Oncogene
Title: Partial functional overlap of the three ras genes in mouse embryonic development.
Volume: 27
Issue: 21
Pages: 2961-8
Publication
First Author: Chiou SH
Year: 2017
Journal: Cancer Discov
Title: BLIMP1 Induces Transient Metastatic Heterogeneity in Pancreatic Cancer.
Volume: 7
Issue: 10
Pages: 1184-1199
Publication
First Author: Chen L
Year: 2010
Journal: Nature
Title: CD95 promotes tumour growth.
Volume: 465
Issue: 7297
Pages: 492-6
Publication
First Author: Budiu RA
Year: 2009
Journal: Dis Model Mech
Title: A conditional mouse model for human MUC1-positive endometriosis shows the presence of anti-MUC1 antibodies and Foxp3+ regulatory T cells.
Volume: 2
Issue: 11-12
Pages: 593-603
Publication
First Author: Morandell S
Year: 2013
Journal: Cell Rep
Title: A reversible gene-targeting strategy identifies synthetic lethal interactions between MK2 and p53 in the DNA damage response in vivo.
Volume: 5
Issue: 4
Pages: 868-77
Publication
First Author: Cheung AF
Year: 2008
Journal: Cancer Res
Title: Regulated expression of a tumor-associated antigen reveals multiple levels of T-cell tolerance in a mouse model of lung cancer.
Volume: 68
Issue: 22
Pages: 9459-68
Publication
First Author: Xu X
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Evidence for type II cells as cells of origin of K-Ras-induced distal lung adenocarcinoma.
Volume: 109
Issue: 13
Pages: 4910-5
Publication
First Author: Liu M
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Targeting the protein prenyltransferases efficiently reduces tumor development in mice with K-RAS-induced lung cancer.
Volume: 107
Issue: 14
Pages: 6471-6
Publication
First Author: Tomić G
Year: 2024
Journal: Cell Rep
Title: Palmitoyl transferase ZDHHC20 promotes pancreatic cancer metastasis.
Volume: 43
Issue: 5
Pages: 114224
Publication
First Author: Blum JM
Year: 2013
Journal: Cell Rep
Title: Distinct and overlapping sarcoma subtypes initiated from muscle stem and progenitor cells.
Volume: 5
Issue: 4
Pages: 933-40
Publication
First Author: Monahan KB
Year: 2010
Journal: Oncogene
Title: Somatic p16(INK4a) loss accelerates melanomagenesis.
Volume: 29
Issue: 43
Pages: 5809-17
Publication  
First Author: Perez BA
Year: 2013
Journal: Front Oncol
Title: Assessing the radiation response of lung cancer with different gene mutations using genetically engineered mice.
Volume: 3
Pages: 72
Publication
First Author: Ho VM
Year: 2009
Journal: Oncogene
Title: The retinoblastoma gene Rb and its family member p130 suppress lung adenocarcinoma induced by oncogenic K-Ras.
Volume: 28
Issue: 10
Pages: 1393-9
Publication
First Author: Seidler B
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: A Cre-loxP-based mouse model for conditional somatic gene expression and knockdown in vivo by using avian retroviral vectors.
Volume: 105
Issue: 29
Pages: 10137-42
Publication
First Author: Heidorn SJ
Year: 2010
Journal: Cell
Title: Kinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAF.
Volume: 140
Issue: 2
Pages: 209-21
Publication
First Author: Skoulidis F
Year: 2010
Journal: Cancer Cell
Title: Germline Brca2 heterozygosity promotes Kras(G12D) -driven carcinogenesis in a murine model of familial pancreatic cancer.
Volume: 18
Issue: 5
Pages: 499-509
Publication  
First Author: Ahmad I
Year: 2011
Journal: Cell Death Dis
Title: Ras mutation cooperates with β-catenin activation to drive bladder tumourigenesis.
Volume: 2
Pages: e124
Publication
First Author: Iwanaga K
Year: 2008
Journal: Cancer Res
Title: Pten inactivation accelerates oncogenic K-ras-initiated tumorigenesis in a mouse model of lung cancer.
Volume: 68
Issue: 4
Pages: 1119-27
Publication
First Author: Yin N
Year: 2019
Journal: Cancer Cell
Title: Protein Kinase Cι and Wnt/β-Catenin Signaling: Alternative Pathways to Kras/Trp53-Driven Lung Adenocarcinoma.
Volume: 36
Issue: 2
Pages: 156-167.e7
Publication
First Author: Bornstein S
Year: 2009
Journal: J Clin Invest
Title: Smad4 loss in mice causes spontaneous head and neck cancer with increased genomic instability and inflammation.
Volume: 119
Issue: 11
Pages: 3408-19
Publication
First Author: Kojima Y
Year: 2023
Journal: Nat Commun
Title: Decreased liver B vitamin-related enzymes as a metabolic hallmark of cancer cachexia.
Volume: 14
Issue: 1
Pages: 6246
Publication
First Author: Muraguchi T
Year: 2011
Journal: Cancer Res
Title: NKX2.2 suppresses self-renewal of glioma-initiating cells.
Volume: 71
Issue: 3
Pages: 1135-45
Publication
First Author: Woolfenden S
Year: 2009
Journal: Genesis
Title: A Cre/LoxP conditional luciferase reporter transgenic mouse for bioluminescence monitoring of tumorigenesis.
Volume: 47
Issue: 10
Pages: 659-66
Publication
First Author: Shi C
Year: 2014
Journal: Lab Invest
Title: Fibrogenesis in pancreatic cancer is a dynamic process regulated by macrophage-stellate cell interaction.
Volume: 94
Issue: 4
Pages: 409-21
Publication      
First Author: DeStefano Shields CE
Year: 2021
Journal: Cancer Discov
Title: Bacterial-Driven Inflammation and Mutant BRAF Expression Combine to Promote Murine Colon Tumorigenesis That Is Sensitive to Immune Checkpoint Therapy.
Publication
First Author: Port J
Year: 2018
Journal: Cancer Discov
Title: Colorectal Tumors Require NUAK1 for Protection from Oxidative Stress.
Volume: 8
Issue: 5
Pages: 632-647
Publication
First Author: Feng Y
Year: 2013
Journal: Am J Pathol
Title: Sox9 induction, ectopic Paneth cells, and mitotic spindle axis defects in mouse colon adenomatous epithelium arising from conditional biallelic Apc inactivation.
Volume: 183
Issue: 2
Pages: 493-503
Publication
First Author: Morris HT
Year: 2018
Journal: J Pathol
Title: Loss of N-WASP drives early progression in an Apc model of intestinal tumourigenesis.
Volume: 245
Issue: 3
Pages: 337-348
Publication
First Author: Zhao Y
Year: 2019
Journal: Sci Rep
Title: Colorectal cancers utilize glutamine as an anaplerotic substrate of the TCA cycle in vivo.
Volume: 9
Issue: 1
Pages: 19180
Publication
First Author: Schepers AG
Year: 2012
Journal: Science
Title: Lineage tracing reveals Lgr5+ stem cell activity in mouse intestinal adenomas.
Volume: 337
Issue: 6095
Pages: 730-5
Publication
First Author: Nakagawa H
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Loss of liver E-cadherin induces sclerosing cholangitis and promotes carcinogenesis.
Volume: 111
Issue: 3
Pages: 1090-5
Publication
First Author: Leushacke M
Year: 2017
Journal: Nat Cell Biol
Title: Lgr5-expressing chief cells drive epithelial regeneration and cancer in the oxyntic stomach.
Volume: 19
Issue: 7
Pages: 774-786
Publication
First Author: Flum M
Year: 2022
Journal: Oncogene
Title: Canonical TGFβ signaling induces collective invasion in colorectal carcinogenesis through a Snail1- and Zeb1-independent partial EMT.
Volume: 41
Issue: 10
Pages: 1492-1506
Publication  
First Author: Liu Y
Year: 2014
Journal: Nat Commun
Title: Different thresholds of ZEB1 are required for Ras-mediated tumour initiation and metastasis.
Volume: 5
Pages: 5660
Publication
First Author: Du W
Year: 2016
Journal: Oncotarget
Title: The Fanconi anemia pathway controls oncogenic response in hematopoietic stem and progenitor cells by regulating PRMT5-mediated p53 arginine methylation.
Volume: 7
Issue: 37
Pages: 60005-60020
Publication
First Author: Juan J
Year: 2014
Journal: Genes Dev
Title: Diminished WNT -> β-catenin -> c-MYC signaling is a barrier for malignant progression of BRAFV600E-induced lung tumors.
Volume: 28
Issue: 6
Pages: 561-75
Publication
First Author: Sherman MH
Year: 2014
Journal: Cell
Title: Vitamin D receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy.
Volume: 159
Issue: 1
Pages: 80-93
Publication
First Author: Tetteh PW
Year: 2016
Journal: Cell Stem Cell
Title: Replacement of Lost Lgr5-Positive Stem Cells through Plasticity of Their Enterocyte-Lineage Daughters.
Volume: 18
Issue: 2
Pages: 203-13
Publication
First Author: Court H
Year: 2013
Journal: J Clin Invest
Title: Isoprenylcysteine carboxylmethyltransferase deficiency exacerbates KRAS-driven pancreatic neoplasia via Notch suppression.
Volume: 123
Issue: 11
Pages: 4681-94
Publication
First Author: Gallini S
Year: 2023
Journal: Nature
Title: Injury prevents Ras mutant cell expansion in mosaic skin.
Volume: 619
Issue: 7968
Pages: 167-175
Publication
First Author: Kennedy AL
Year: 2011
Journal: Mol Cell
Title: Activation of the PIK3CA/AKT pathway suppresses senescence induced by an activated RAS oncogene to promote tumorigenesis.
Volume: 42
Issue: 1
Pages: 36-49
Publication
First Author: Aykut B
Year: 2019
Journal: Nature
Title: The fungal mycobiome promotes pancreatic oncogenesis via activation of MBL.
Volume: 574
Issue: 7777
Pages: 264-267
Publication
First Author: Aguilera KY
Year: 2014
Journal: Cancer Res
Title: Collagen signaling enhances tumor progression after anti-VEGF therapy in a murine model of pancreatic ductal adenocarcinoma.
Volume: 74
Issue: 4
Pages: 1032-44
Publication
First Author: Pastushenko I
Year: 2021
Journal: Nature
Title: Fat1 deletion promotes hybrid EMT state, tumour stemness and metastasis.
Volume: 589
Issue: 7842
Pages: 448-455
Publication
First Author: Lapouge G
Year: 2012
Journal: EMBO J
Title: Skin squamous cell carcinoma propagating cells increase with tumour progression and invasiveness.
Volume: 31
Issue: 24
Pages: 4563-75
Publication
First Author: Beck B
Year: 2015
Journal: Cell Stem Cell
Title: Different levels of Twist1 regulate skin tumor initiation, stemness, and progression.
Volume: 16
Issue: 1
Pages: 67-79
Publication
First Author: Kidger AM
Year: 2022
Journal: Oncogene
Title: Suppression of mutant Kirsten-RAS (KRASG12D)-driven pancreatic carcinogenesis by dual-specificity MAP kinase phosphatases 5 and 6.
Volume: 41
Issue: 20
Pages: 2811-2823
Publication
First Author: Prieto LI
Year: 2023
Journal: Cancer Cell
Title: Senescent alveolar macrophages promote early-stage lung tumorigenesis.
Volume: 41
Issue: 7
Pages: 1261-1275.e6
Publication
First Author: Zhao B
Year: 2009
Journal: EMBO Rep
Title: Cellular senescence and organismal ageing in the absence of p21(CIP1/WAF1) in ku80(-/-) mice.
Volume: 10
Issue: 1
Pages: 71-8
Publication
First Author: Jiang H
Year: 2016
Journal: Nat Med
Title: Targeting focal adhesion kinase renders pancreatic cancers responsive to checkpoint immunotherapy.
Volume: 22
Issue: 8
Pages: 851-60
Publication  
First Author: Robles-Oteiza C
Year: 2015
Journal: Nat Commun
Title: Recombinase-based conditional and reversible gene regulation via XTR alleles.
Volume: 6
Pages: 8783
Publication  
First Author: Lee JY
Year: 2023
Journal: Cells
Title: Runx3 Restoration Regresses K-Ras-Activated Mouse Lung Cancers and Inhibits Recurrence.
Volume: 12
Issue: 20
Publication
First Author: Millar FR
Year: 2022
Journal: Cell Rep
Title: Toll-like receptor 2 orchestrates a tumor suppressor response in non-small cell lung cancer.
Volume: 41
Issue: 6
Pages: 111596
Publication
First Author: Whitley MJ
Year: 2016
Journal: Sci Transl Med
Title: A mouse-human phase 1 co-clinical trial of a protease-activated fluorescent probe for imaging cancer.
Volume: 8
Issue: 320
Pages: 320ra4
Publication
First Author: Somani VK
Year: 2022
Journal: Gastroenterology
Title: IRAK4 Signaling Drives Resistance to Checkpoint Immunotherapy in Pancreatic Ductal Adenocarcinoma.
Volume: 162
Issue: 7
Pages: 2047-2062
Publication
First Author: Tan X
Year: 2021
Journal: Nat Commun
Title: Loss of Smad4 promotes aggressive lung cancer metastasis by de-repression of PAK3 via miRNA regulation.
Volume: 12
Issue: 1
Pages: 4853
Publication
First Author: Cheung EC
Year: 2020
Journal: Cancer Cell
Title: Dynamic ROS Control by TIGAR Regulates the Initiation and Progression of Pancreatic Cancer.
Volume: 37
Issue: 2
Pages: 168-182.e4
Publication
First Author: Caswell DR
Year: 2014
Journal: Cancer Discov
Title: Obligate progression precedes lung adenocarcinoma dissemination.
Volume: 4
Issue: 7
Pages: 781-9
Publication
First Author: Schmitt A
Year: 2017
Journal: Cancer Res
Title: ATM Deficiency Is Associated with Sensitivity to PARP1- and ATR Inhibitors in Lung Adenocarcinoma.
Volume: 77
Issue: 11
Pages: 3040-3056
Publication
First Author: Assouline B
Year: 2024
Journal: Nat Commun
Title: Senescent cancer-associated fibroblasts in pancreatic adenocarcinoma restrict CD8(+) T cell activation and limit responsiveness to immunotherapy in mice.
Volume: 15
Issue: 1
Pages: 6162
Publication
First Author: Burger ML
Year: 2021
Journal: Cell
Title: Antigen dominance hierarchies shape TCF1+ progenitor CD8 T cell phenotypes in tumors.
Volume: 184
Issue: 19
Pages: 4996-5014.e26
Publication  
First Author: Taylor AJ
Year: 2023
Journal: Mol Metab
Title: Islet amyloid polypeptide does not suppress pancreatic cancer.
Volume: 68
Pages: 101667
Publication
First Author: Kumar MS
Year: 2009
Journal: Genes Dev
Title: Dicer1 functions as a haploinsufficient tumor suppressor.
Volume: 23
Issue: 23
Pages: 2700-4
Publication
First Author: Dodd RD
Year: 2016
Journal: Oncogene
Title: Myogenic transcription factors regulate pro-metastatic miR-182.
Volume: 35
Issue: 14
Pages: 1868-75
Publication
First Author: Cheung PF
Year: 2022
Journal: Nat Commun
Title: Progranulin mediates immune evasion of pancreatic ductal adenocarcinoma through regulation of MHCI expression.
Volume: 13
Issue: 1
Pages: 156
Publication
First Author: Patel RS
Year: 2022
Journal: Nat Commun
Title: A GATA4-regulated secretory program suppresses tumors through recruitment of cytotoxic CD8 T cells.
Volume: 13
Issue: 1
Pages: 256
Publication
First Author: Murray CW
Year: 2022
Journal: Nat Commun
Title: LKB1 drives stasis and C/EBP-mediated reprogramming to an alveolar type II fate in lung cancer.
Volume: 13
Issue: 1
Pages: 1090
Publication      
First Author: Tang Z
Year: 2024
Journal: Dev Cell
Title: A subset of neutrophils activates anti-tumor immunity and inhibits non-small-cell lung cancer progression.
Publication
First Author: Zavitsanou AM
Year: 2023
Journal: Cell Rep
Title: KEAP1 mutation in lung adenocarcinoma promotes immune evasion and immunotherapy resistance.
Volume: 42
Issue: 11
Pages: 113295
Publication    
First Author: Kang YP
Year: 2019
Journal: Elife
Title: Cysteine dioxygenase 1 is a metabolic liability for non-small cell lung cancer.
Volume: 8
Publication
First Author: Schug C
Year: 2019
Journal: Mol Cancer Res
Title: A Novel Approach for Image-Guided 131I Therapy of Pancreatic Ductal Adenocarcinoma Using Mesenchymal Stem Cell-Mediated NIS Gene Delivery.
Volume: 17
Issue: 1
Pages: 310-320
Publication
First Author: Bermejo-Rodriguez C
Year: 2024
Journal: Cancer Res
Title: Scribble Deficiency Promotes Pancreatic Ductal Adenocarcinoma Development and Metastasis.
Volume: 84
Issue: 18
Pages: 2968-2984
Publication
First Author: Zhang W
Year: 2014
Journal: Cell Res
Title: VGLL4 functions as a new tumor suppressor in lung cancer by negatively regulating the YAP-TEAD transcriptional complex.
Volume: 24
Issue: 3
Pages: 331-43
Publication
First Author: Liu Y
Year: 2017
Journal: Cancer Res
Title: Gemcitabine and Chk1 Inhibitor AZD7762 Synergistically Suppress the Growth of Lkb1-Deficient Lung Adenocarcinoma.
Volume: 77
Issue: 18
Pages: 5068-5076
Publication
First Author: Song M
Year: 2018
Journal: Nature
Title: IRE1α-XBP1 controls T cell function in ovarian cancer by regulating mitochondrial activity.
Volume: 562
Issue: 7727
Pages: 423-428
Publication
First Author: Morris JP 4th
Year: 2019
Journal: Nature
Title: α-Ketoglutarate links p53 to cell fate during tumour suppression.
Volume: 573
Issue: 7775
Pages: 595-599
Publication
First Author: Reynoird N
Year: 2016
Journal: Genes Dev
Title: Coordination of stress signals by the lysine methyltransferase SMYD2 promotes pancreatic cancer.
Volume: 30
Issue: 7
Pages: 772-85
Publication
First Author: Messenger ZJ
Year: 2018
Journal: Cell Death Dis
Title: C/EBPβ deletion in oncogenic Ras skin tumors is a synthetic lethal event.
Volume: 9
Issue: 11
Pages: 1054
Publication  
First Author: Rossi Sebastiano M
Year: 2020
Journal: Sci Adv
Title: ACSL3-PAI-1 signaling axis mediates tumor-stroma cross-talk promoting pancreatic cancer progression.
Volume: 6
Issue: 44
Publication
First Author: Fujimoto TN
Year: 2019
Journal: Cancer Res
Title: Selective EGLN Inhibition Enables Ablative Radiotherapy and Improves Survival in Unresectable Pancreatic Cancer.
Volume: 79
Issue: 9
Pages: 2327-2338
Publication  
First Author: Masuda T
Year: 2023
Journal: J Clin Invest
Title: Pancreatic RECK inactivation promotes cancer formation, epithelial-mesenchymal transition, and metastasis.
Volume: 133
Issue: 18
Publication
First Author: Sugiyama Y
Year: 2016
Journal: Pol J Pathol
Title: Gli2 protein expression level is a feasible marker of ligand-dependent hedgehog activation in pancreatic neoplasms.
Volume: 67
Issue: 2
Pages: 136-44
Publication
First Author: Shi Y
Year: 2019
Journal: Nature
Title: Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring.
Volume: 569
Issue: 7754
Pages: 131-135