|  Help  |  About  |  Contact Us

Search our database by keyword

- or -

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1601 to 1700 out of 2663 for Psen1

Category restricted to Publication (x)

<< First    < Previous  |  Next >    Last >>
0.039s

Categories

Category: Publication
« show all
Type Details Score
Publication
37892143 | J:342917
 
First Author: Abghari M
Year: 2023
Journal: Biomolecules
Title: Decanoic Acid Rescues Differences in AMPA-Mediated Calcium Rises in Hippocampal CA1 Astrocytes and Neurons in the 5xFAD Mouse Model of Alzheimer's Disease.
Volume: 13
Issue: 10
•
•
•
•
•
Publication
34512311 | J:311098
 
First Author: Shen Y
Year: 2021
Journal: Front Aging Neurosci
Title: Stress Granules Modulate SYK to Cause Tau-Associated Neurocognitive Deterioration in 5XFAD Mouse After Anesthesia and Surgery.
Volume: 13
Pages: 718701
•
•
•
•
•
Publication
37245024 | J:348190
First Author: Lantz MJ
Year: 2023
Journal: J Neuroinflammation
Title: The neuroprotective N-terminal amyloid-β core hexapeptide reverses reactive gliosis and gliotoxicity in Alzheimer's disease pathology models.
Volume: 20
Issue: 1
Pages: 129
•
•
•
•
•
Publication
36635496 | J:348189
First Author: van Lengerich B
Year: 2023
Journal: Nat Neurosci
Title: A TREM2-activating antibody with a blood-brain barrier transport vehicle enhances microglial metabolism in Alzheimer's disease models.
Volume: 26
Issue: 3
Pages: 416-429
•
•
•
•
•
Publication
37561584 | J:348192
 
First Author: Gould NL
Year: 2023
Journal: J Clin Invest
Title: Specific quinone reductase 2 inhibitors reduce metabolic burden and reverse Alzheimer's disease phenotype in mice.
Volume: 133
Issue: 19
•
•
•
•
•
Publication
28302071 | J:241867
First Author: Bundy JL
Year: 2017
Journal: BMC Genomics
Title: Sex differences in the molecular signature of the developing mouse hippocampus.
Volume: 18
Issue: 1
Pages: 237
•
•
•
•
•
Publication
37762276 | J:348191
 
First Author: Rakovskaya A
Year: 2023
Journal: Int J Mol Sci
Title: Positive Allosteric Modulators of SERCA Pump Restore Dendritic Spines and Rescue Long-Term Potentiation Defects in Alzheimer's Disease Mouse Model.
Volume: 24
Issue: 18
•
•
•
•
•
Publication
37072933 | J:354106
First Author: Zhang D
Year: 2023
Journal: CNS Neurosci Ther
Title: Degradation of NLRP3 by p62-dependent-autophagy improves cognitive function in Alzheimer's disease by maintaining the phagocytic function of microglia.
Volume: 29
Issue: 10
Pages: 2826-2842
•
•
•
•
•
Publication
30254165 | J:266528
First Author: Baker SK
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Blood-derived plasminogen drives brain inflammation and plaque deposition in a mouse model of Alzheimer's disease.
Volume: 115
Issue: 41
Pages: E9687-E9696
•
•
•
•
•
Publication
38461954 | J:346661
 
First Author: Iban-Arias R
Year: 2024
Journal: Brain Behav Immun
Title: Ad-derived bone marrow transplant induces proinflammatory immune peripheral mechanisms accompanied by decreased neuroplasticity and reduced gut microbiome diversity affecting AD-like phenotype in the absence of Aβ neuropathology.
Volume: 118
Pages: 252-272
•
•
•
•
•
Publication
38042775 | J:343464
First Author: Zeng X
Year: 2023
Journal: J Neuroinflammation
Title: Astrocyte-specific knockout of YKL-40/Chi3l1 reduces Aβ burden and restores memory functions in 5xFAD mice.
Volume: 20
Issue: 1
Pages: 290
•
•
•
•
•
Publication
31001105 | J:275348
 
First Author: Kaylegian K
Year: 2019
Journal: Front Aging Neurosci
Title: 5XFAD Mice Show Early Onset Gap Detection Deficits.
Volume: 11
Pages: 66
•
•
•
•
•
Publication
37551444 | J:346663
First Author: Keramidis I
Year: 2023
Journal: Brain
Title: Restoring neuronal chloride extrusion reverses cognitive decline linked to Alzheimer's disease mutations.
Volume: 146
Issue: 12
Pages: 4903-4915
•
•
•
•
•
Publication
35760863 | J:335650
First Author: Kenigsbuch M
Year: 2022
Journal: Nat Neurosci
Title: A shared disease-associated oligodendrocyte signature among multiple CNS pathologies.
Volume: 25
Issue: 7
Pages: 876-886
•
•
•
•
•
Publication
30001512 | J:270047
First Author: Eimer WA
Year: 2018
Journal: Neuron
Title: Alzheimer's Disease-Associated β-Amyloid Is Rapidly Seeded by Herpesviridae to Protect against Brain Infection.
Volume: 99
Issue: 1
Pages: 56-63.e3
•
•
•
•
•
Publication
35727131 | J:333617
   
First Author: Olah VJ
Year: 2022
Journal: Elife
Title: Biophysical K(v)3 channel alterations dampen excitability of cortical PV interneurons and contribute to network hyperexcitability in early Alzheimer's.
Volume: 11
•
•
•
•
•
Publication
38095816 | J:357504
First Author: Li D
Year: 2023
Journal: Front Optoelectron
Title: Photostimulation of lymphatic clearance of β-amyloid from mouse brain: a new strategy for the therapy of Alzheimer's disease.
Volume: 16
Issue: 1
Pages: 45
•
•
•
•
•
Publication
24725413 | J:208030
First Author: Seo J
Year: 2014
Journal: Cell
Title: Activity-dependent p25 generation regulates synaptic plasticity and Aβ-induced cognitive impairment.
Volume: 157
Issue: 2
Pages: 486-498
•
•
•
•
•
Publication
34371179 | J:354115
First Author: Markoutsa E
Year: 2022
Journal: Mol Ther
Title: Extracellular vesicles derived from inflammatory-educated stem cells reverse brain inflammation-implication of miRNAs.
Volume: 30
Issue: 2
Pages: 816-830
•
•
•
•
•
Publication
38254666 | J:348216
 
First Author: Wang E
Year: 2024
Journal: Biomolecules
Title: Proteomic Signaling of Dual-Specificity Phosphatase 4 (DUSP4) in Alzheimer's Disease.
Volume: 14
Issue: 1
•
•
•
•
•
Publication
33452414 | J:300382
First Author: Shin J
Year: 2021
Journal: Sci Rep
Title: Thioflavin-positive tau aggregates complicating quantification of amyloid plaques in the brain of 5XFAD transgenic mouse model.
Volume: 11
Issue: 1
Pages: 1617
•
•
•
•
•
Publication
35180881 | J:351565
First Author: Tsai AP
Year: 2022
Journal: Genome Med
Title: PLCG2 is associated with the inflammatory response and is induced by amyloid plaques in Alzheimer's disease.
Volume: 14
Issue: 1
Pages: 17
•
•
•
•
•
Publication
36450991 | J:340267
First Author: Yuan P
Year: 2022
Journal: Nature
Title: PLD3 affects axonal spheroids and network defects in Alzheimer's disease.
Volume: 612
Issue: 7939
Pages: 328-337
•
•
•
•
•
Publication
38396919 | J:348217
 
First Author: Mast N
Year: 2024
Journal: Int J Mol Sci
Title: 7,8-Dihydroxy Efavirenz Is Not as Effective in CYP46A1 Activation In Vivo as Efavirenz or Its 8,14-Dihydroxy Metabolite.
Volume: 25
Issue: 4
•
•
•
•
•
Publication
24069328 | J:206029
First Author: Crouzin N
Year: 2013
Journal: PLoS One
Title: Area-specific alterations of synaptic plasticity in the 5XFAD mouse model of Alzheimer's disease: dissociation between somatosensory cortex and hippocampus.
Volume: 8
Issue: 9
Pages: e74667
•
•
•
•
•
Publication
38036784 | J:351569
First Author: Sziraki A
Year: 2023
Journal: Nat Genet
Title: A global view of aging and Alzheimer's pathogenesis-associated cell population dynamics and molecular signatures in human and mouse brains.
Volume: 55
Issue: 12
Pages: 2104-2116
•
•
•
•
•
Publication
39588497 | J:358919
 
First Author: Yuan L
Year: 2024
Journal: Front Neurosci
Title: Diethyl butylmalonate attenuates cognitive deficits and depression in 5×FAD mice.
Volume: 18
Pages: 1480000
•
•
•
•
•
Publication
38676929 | J:351572
First Author: Pandey RS
Year: 2024
Journal: Alzheimers Dement
Title: Metabolomics profiling reveals distinct, sex-specific signatures in serum and brain metabolomes in mouse models of Alzheimer's disease.
Volume: 20
Issue: 6
Pages: 3987-4001
•
•
•
•
•
Publication
38531510 | J:348219
 
First Author: O'Leary TP
Year: 2024
Journal: Behav Brain Res
Title: Age-related changes in species-typical behaviours in the 5xFAD mouse model of Alzheimer's disease from 4 to 16 months of age.
Volume: 465
Pages: 114970
•
•
•
•
•
Publication
35740989 | J:327554
 
First Author: Espinoza S
Year: 2022
Journal: Cells
Title: Neuronal Rubicon Represses Extracellular APP/Amyloid β Deposition in Alzheimer's Disease.
Volume: 11
Issue: 12
•
•
•
•
•
Publication
33817786 | J:353374
First Author: Vasilopoulou F
Year: 2021
Journal: Br J Pharmacol
Title: Disease-modifying treatment with I(2) imidazoline receptor ligand LSL60101 in an Alzheimer's disease mouse model: a comparative study with donepezil.
Volume: 178
Issue: 15
Pages: 3017-3033
•
•
•
•
•
Publication
37453419 | J:353968
First Author: Kumar A
Year: 2023
Journal: Neuron
Title: 2-Deoxyglucose drives plasticity via an adaptive ER stress-ATF4 pathway and elicits stroke recovery and Alzheimer's resilience.
Volume: 111
Issue: 18
Pages: 2831-2846.e10
•
•
•
•
•
Publication
26942905 | J:301968
First Author: Wang L
Year: 2016
Journal: PLoS One
Title: Synaptosomal Mitochondrial Dysfunction in 5xFAD Mouse Model of Alzheimer's Disease.
Volume: 11
Issue: 3
Pages: e0150441
•
•
•
•
•
Publication
29164616 | J:257177
First Author: Forest KH
Year: 2018
Journal: J Neurochem
Title: Protection against β-amyloid neurotoxicity by a non-toxic endogenous N-terminal β-amyloid fragment and its active hexapeptide core sequence.
Volume: 144
Issue: 2
Pages: 201-217
•
•
•
•
•
Publication
29107146 | J:274302
First Author: Jang JY
Year: 2018
Journal: Biochim Biophys Acta Gen Subj
Title: NABi, a novel β-sheet breaker, inhibits Aβ aggregation and neuronal toxicity: Therapeutic implications for Alzheimer's disease.
Volume: 1862
Issue: 1
Pages: 71-80
•
•
•
•
•
Publication
35236374 | J:321997
First Author: Ren X
Year: 2022
Journal: J Neuroinflammation
Title: Microglial VPS35 deficiency impairs Aβ phagocytosis and Aβ-induced disease-associated microglia, and enhances Aβ associated pathology.
Volume: 19
Issue: 1
Pages: 61
•
•
•
•
•
Publication
29321508 | J:260155
First Author: Kim DH
Year: 2018
Journal: Sci Rep
Title: Thrombospondin-1 secreted by human umbilical cord blood-derived mesenchymal stem cells rescues neurons from synaptic dysfunction in Alzheimer's disease model.
Volume: 8
Issue: 1
Pages: 354
•
•
•
•
•
Publication
38497356 | J:348220
First Author: Palko SI
Year: 2024
Journal: Glia
Title: ER-stress response in retinal Müller glia occurs significantly earlier than amyloid pathology in the Alzheimer's mouse brain and retina.
Volume: 72
Issue: 6
Pages: 1067-1081
•
•
•
•
•
Publication
32890775 | J:300482
 
First Author: von Saucken VE
Year: 2020
Journal: Neurobiol Dis
Title: The effect of amyloid on microglia-neuron interactions before plaque onset occurs independently of TREM2 in a mouse model of Alzheimer's disease.
Volume: 145
Pages: 105072
•
•
•
•
•
Publication
21148560 | J:169481
First Author: Jawhar S
Year: 2011
Journal: J Biol Chem
Title: Overexpression of glutaminyl cyclase, the enzyme responsible for pyroglutamate A{beta} formation, induces behavioral deficits, and glutaminyl cyclase knock-out rescues the behavioral phenotype in 5XFAD mice.
Volume: 286
Issue: 6
Pages: 4454-60
•
•
•
•
•
Publication
34052228 | J:311262
First Author: Bocharova O
Year: 2021
Journal: J Biol Chem
Title: Alzheimer's disease-associated β-amyloid does not protect against herpes simplex virus 1 infection in the mouse brain.
Volume: 297
Issue: 1
Pages: 100845
•
•
•
•
•
Publication
34021136 | J:311264
First Author: Grubman A
Year: 2021
Journal: Nat Commun
Title: Transcriptional signature in microglia associated with Aβ plaque phagocytosis.
Volume: 12
Issue: 1
Pages: 3015
•
•
•
•
•
Publication
32341542 | J:293161
First Author: Habib N
Year: 2020
Journal: Nat Neurosci
Title: Disease-associated astrocytes in Alzheimer's disease and aging.
Volume: 23
Issue: 6
Pages: 701-706
•
•
•
•
•
Publication
33882308 | J:311269
First Author: Prince SM
Year: 2021
Journal: Cell Rep
Title: Alzheimer's pathology causes impaired inhibitory connections and reactivation of spatial codes during spatial navigation.
Volume: 35
Issue: 3
Pages: 109008
•
•
•
•
•
Publication
34366774 | J:348221
 
First Author: Zhang M
Year: 2021
Journal: Front Neurosci
Title: Brain and Retinal Abnormalities in the 5xFAD Mouse Model of Alzheimer's Disease at Early Stages.
Volume: 15
Pages: 681831
•
•
•
•
•
Publication
34103615 | J:311273
First Author: Park S
Year: 2021
Journal: Sci Rep
Title: Quinacrine directly dissociates amyloid plaques in the brain of 5XFAD transgenic mouse model of Alzheimer's disease.
Volume: 11
Issue: 1
Pages: 12043
•
•
•
•
•
Publication
34127752 | J:311274
First Author: Kim E
Year: 2021
Journal: Sci Rep
Title: In vivo multi-parametric manganese-enhanced MRI for detecting amyloid plaques in rodent models of Alzheimer's disease.
Volume: 11
Issue: 1
Pages: 12419
•
•
•
•
•
Publication
27791467 | J:311270
First Author: Fan Y
Year: 2017
Journal: Autophagy
Title: Identification of natural products with neuronal and metabolic benefits through autophagy induction.
Volume: 13
Issue: 1
Pages: 41-56
•
•
•
•
•
Publication
34138944 | J:311272
First Author: Fukui K
Year: 2021
Journal: PLoS One
Title: Effects of far infrared light on Alzheimer's disease-transgenic mice.
Volume: 16
Issue: 6
Pages: e0253320
•
•
•
•
•
Publication
35222363 | J:348223
 
First Author: Lee HJ
Year: 2022
Journal: Front Immunol
Title: Idebenone Regulates Aβ and LPS-Induced Neurogliosis and Cognitive Function Through Inhibition of NLRP3 Inflammasome/IL-1β Axis Activation.
Volume: 13
Pages: 749336
•
•
•
•
•
Publication
33857550 | J:311277
 
First Author: Daini E
Year: 2021
Journal: Neurosci Lett
Title: A regional and cellular analysis of the early intracellular and extracellular accumulation of Aβ in the brain of 5XFAD mice.
Volume: 754
Pages: 135869
•
•
•
•
•
Publication
34998934 | J:348222
 
First Author: Chen L
Year: 2022
Journal: Free Radic Biol Med
Title: Enhanced defense against ferroptosis ameliorates cognitive impairment and reduces neurodegeneration in 5xFAD mice.
Volume: 180
Pages: 1-12
•
•
•
•
•
Publication
34246283 | J:311278
First Author: Choi M
Year: 2021
Journal: Mol Brain
Title: Disruption of the astrocyte-neuron interaction is responsible for the impairments in learning and memory in 5XFAD mice: an Alzheimer's disease animal model.
Volume: 14
Issue: 1
Pages: 111
•
•
•
•
•
Publication
33672967 | J:311243
 
First Author: Teafatiller T
Year: 2021
Journal: Nutrients
Title: Upregulation of Vitamin C Transporter Functional Expression in 5xFAD Mouse Intestine.
Volume: 13
Issue: 2
•
•
•
•
•
Publication
39428563 | J:359011
First Author: Ma X
Year: 2024
Journal: CNS Neurosci Ther
Title: Novel Insights Into DLAT's Role in Alzheimer's Disease-Related Copper Toxicity Through Microglial Exosome Dynamics.
Volume: 30
Issue: 10
Pages: e70064
•
•
•
•
•
Publication
34122447 | J:311286
 
First Author: Kim J
Year: 2021
Journal: Front Immunol
Title: Sorafenib Modulates the LPS- and Aβ-Induced Neuroinflammatory Response in Cells, Wild-Type Mice, and 5xFAD Mice.
Volume: 12
Pages: 684344
•
•
•
•
•
Publication
33117125 | J:311245
 
First Author: Angeli S
Year: 2020
Journal: Front Neurosci
Title: Altered Expression of Glial Gap Junction Proteins Cx43, Cx30, and Cx47 in the 5XFAD Model of Alzheimer's Disease.
Volume: 14
Pages: 582934
•
•
•
•
•
Publication
37040764 | J:335540
     
First Author: Hou X
Year: 2023
Journal: Neuron
Title: Differential and substrate-specific inhibition of γ-secretase by the C-terminal region of ApoE2, ApoE3, and ApoE4.
•
•
•
•
•
Publication
35705056 | J:326053
First Author: Kiani Shabestari S
Year: 2022
Journal: Cell Rep
Title: Absence of microglia promotes diverse pathologies and early lethality in Alzheimer's disease mice.
Volume: 39
Issue: 11
Pages: 110961
•
•
•
•
•
Publication
33005179 | J:311246
 
First Author: Zhu M
Year: 2020
Journal: Front Genet
Title: Identification of KIAA0513 and Other Hub Genes Associated With Alzheimer Disease Using Weighted Gene Coexpression Network Analysis.
Volume: 11
Pages: 981
•
•
•
•
•
Publication
34315969 | J:311288
First Author: Lauer AA
Year: 2021
Journal: Sci Rep
Title: Shotgun lipidomics of liver and brain tissue of Alzheimer's disease model mice treated with acitretin.
Volume: 11
Issue: 1
Pages: 15301
•
•
•
•
•
Publication
32733889 | J:311251
 
First Author: Mitroshina EV
Year: 2020
Journal: Front Cell Dev Biol
Title: Brain-Derived Neurotrophic Factor (BDNF) Preserves the Functional Integrity of Neural Networks in the β-Amyloidopathy Model in vitro.
Volume: 8
Pages: 582
•
•
•
•
•
Publication
34065168 | J:311252
 
First Author: López-Gambero AJ
Year: 2021
Journal: Int J Mol Sci
Title: A Negative Energy Balance Is Associated with Metabolic Dysfunctions in the Hypothalamus of a Humanized Preclinical Model of Alzheimer's Disease, the 5XFAD Mouse.
Volume: 22
Issue: 10
•
•
•
•
•
Publication
35706029 | J:326046
First Author: Jäntti H
Year: 2022
Journal: J Neuroinflammation
Title: Microglial amyloid beta clearance is driven by PIEZO1 channels.
Volume: 19
Issue: 1
Pages: 147
•
•
•
•
•
Publication
28980867 | J:311253
First Author: Yang C
Year: 2017
Journal: Autophagy
Title: NRBF2 is involved in the autophagic degradation process of APP-CTFs in Alzheimer disease models.
Volume: 13
Issue: 12
Pages: 2028-2040
•
•
•
•
•
Publication
34503586 | J:311254
First Author: Delizannis AT
Year: 2021
Journal: Acta Neuropathol Commun
Title: Effects of microglial depletion and TREM2 deficiency on Aβ plaque burden and neuritic plaque tau pathology in 5XFAD mice.
Volume: 9
Issue: 1
Pages: 150
•
•
•
•
•
Publication
33250918 | J:311247
 
First Author: Song Z
Year: 2020
Journal: Front Genet
Title: Comprehensive Proteomic Profiling of Urinary Exosomes and Identification of Potential Non-invasive Early Biomarkers of Alzheimer's Disease in 5XFAD Mouse Model.
Volume: 11
Pages: 565479
•
•
•
•
•
Publication
32903751 | J:311248
 
First Author: Kim JS
Year: 2020
Journal: Front Neurosci
Title: Conductive Hearing Loss Aggravates Memory Decline in Alzheimer Model Mice.
Volume: 14
Pages: 843
•
•
•
•
•
Publication
32973454 | J:311250
 
First Author: Guan Z
Year: 2020
Journal: Front Cell Neurosci
Title: Progranulin Administration Attenuates β-Amyloid Deposition in the Hippocampus of 5xFAD Mice Through Modulating BACE1 Expression and Microglial Phagocytosis.
Volume: 14
Pages: 260
•
•
•
•
•
Publication
34203049 | J:311293
 
First Author: Shal B
Year: 2021
Journal: Int J Mol Sci
Title: Alleviation of Memory Deficit by Bergenin via the Regulation of Reelin and Nrf-2/NF-κB Pathway in Transgenic Mouse Model.
Volume: 22
Issue: 12
•
•
•
•
•
Publication
36362339 | J:331579
 
First Author: Zernov N
Year: 2022
Journal: Int J Mol Sci
Title: New Positive TRPC6 Modulator Penetrates Blood-Brain Barrier, Eliminates Synaptic Deficiency and Restores Memory Deficit in 5xFAD Mice.
Volume: 23
Issue: 21
•
•
•
•
•
Publication
31998073 | J:284853
 
First Author: Nam KI
Year: 2019
Journal: Front Mol Neurosci
Title: Transcriptome Analysis of Pineal Glands in the Mouse Model of Alzheimer's Disease.
Volume: 12
Pages: 318
•
•
•
•
•
Publication
32141089 | J:297501
First Author: Kaya I
Year: 2020
Journal: J Neurochem
Title: Brain region-specific amyloid plaque-associated myelin lipid loss, APOE deposition and disruption of the myelin sheath in familial Alzheimer's disease mice.
Volume: 154
Issue: 1
Pages: 84-98
•
•
•
•
•
Publication
26358770 | J:226496
First Author: Cha MY
Year: 2015
Journal: Hum Mol Genet
Title: Mitochondrial ATP synthase activity is impaired by suppressed O-GlcNAcylation in Alzheimer's disease.
Volume: 24
Issue: 22
Pages: 6492-504
•
•
•
•
•
Publication
23499006 | J:198127
First Author: Brower CS
Year: 2013
Journal: Mol Cell
Title: Neurodegeneration-associated protein fragments as short-lived substrates of the N-end rule pathway.
Volume: 50
Issue: 2
Pages: 161-71
•
•
•
•
•
Publication
38670277 | J:348408
 
First Author: Rodrigues MES
Year: 2024
Journal: Neurobiol Dis
Title: Diet-induced metabolic and immune impairments are sex-specifically modulated by soluble TNF signaling in the 5xFAD mouse model of Alzheimer's disease.
Volume: 196
Pages: 106511
•
•
•
•
•
Publication
35721135 | J:326117
 
First Author: El-Darzi N
Year: 2022
Journal: Front Pharmacol
Title: Low-Dose Anti-HIV Drug Efavirenz Mitigates Retinal Vascular Lesions in a Mouse Model of Alzheimer's Disease.
Volume: 13
Pages: 902254
•
•
•
•
•
Publication
31381246 | J:284896
First Author: O'Connell KMS
Year: 2019
Journal: Genes Brain Behav
Title: Genetic background modifies CNS-mediated sensorimotor decline in the AD-BXD mouse model of genetic diversity in Alzheimer's disease.
Volume: 18
Issue: 8
Pages: e12603
•
•
•
•
•
Publication
32966798 | J:311228
First Author: Yao J
Year: 2020
Journal: Cell Rep
Title: Limiting RyR2 Open Time Prevents Alzheimer's Disease-Related Neuronal Hyperactivity and Memory Loss but Not β-Amyloid Accumulation.
Volume: 32
Issue: 12
Pages: 108169
•
•
•
•
•
Publication
33677013 | J:311229
 
First Author: Gendron WH
Year: 2021
Journal: Behav Brain Res
Title: Age related weight loss in female 5xFAD mice from 3 to 12 months of age.
Volume: 406
Pages: 113214
•
•
•
•
•
Publication
26091071 | J:348415
 
First Author: Li S
Year: 2015
Journal: Sci Rep
Title: Swedish mutant APP-based BACE1 binding site peptide reduces APP β-cleavage and cerebral Aβ levels in Alzheimer's mice.
Volume: 5
Pages: 11322
•
•
•
•
•
Publication
31804596 | J:311230
First Author: Binyamin O
Year: 2019
Journal: Sci Rep
Title: Brain targeting of 9c,11t-Conjugated Linoleic Acid, a natural calpain inhibitor, preserves memory and reduces Aβ and P25 accumulation in 5XFAD mice.
Volume: 9
Issue: 1
Pages: 18437
•
•
•
•
•
Publication
34247115 | J:351789
 
First Author: Ren D
Year: 2021
Journal: Phytomedicine
Title: Tetrandrine ameliorated Alzheimer's disease through suppressing microglial inflammatory activation and neurotoxicity in the 5XFAD mouse.
Volume: 90
Pages: 153627
•
•
•
•
•
Publication
34366832 | J:341530
 
First Author: Oblak AL
Year: 2021
Journal: Front Aging Neurosci
Title: Comprehensive Evaluation of the 5XFAD Mouse Model for Preclinical Testing Applications: A MODEL-AD Study.
Volume: 13
Pages: 713726
•
•
•
•
•
Publication
38296900 | J:359067
First Author: Petralla S
Year: 2024
Journal: Mol Neurobiol
Title: Increased Expression of Transferrin Receptor 1 in the Brain Cortex of 5xFAD Mouse Model of Alzheimer's Disease Is Associated with Activation of HIF-1 Signaling Pathway.
Volume: 61
Issue: 9
Pages: 6383-6394
•
•
•
•
•
Publication
36907286 | J:351751
 
First Author: Lee HJ
Year: 2023
Journal: Pharmacol Res
Title: Inhibition of CDK4/6 regulates AD pathology, neuroinflammation and cognitive function through DYRK1A/STAT3 signaling.
Volume: 190
Pages: 106725
•
•
•
•
•
Publication
36831849 | J:351748
 
First Author: Ilina A
Year: 2023
Journal: Brain Sci
Title: A Transgenic 5xFAD-M Line of Mice for Dendritic Spine Morphology Analysis in Alzheimer's Disease.
Volume: 13
Issue: 2
•
•
•
•
•
Publication
33839232 | J:311255
 
First Author: Liu Q
Year: 2021
Journal: Brain Behav Immun
Title: Mannan oligosaccharide attenuates cognitive and behavioral disorders in the 5xFAD Alzheimer's disease mouse model via regulating the gut microbiota-brain axis.
Volume: 95
Pages: 330-343
•
•
•
•
•
Publication
34531467 | J:311256
First Author: Behof WJ
Year: 2021
Journal: Sci Rep
Title: A novel antioxidant ergothioneine PET radioligand for in vivo imaging applications.
Volume: 11
Issue: 1
Pages: 18450
•
•
•
•
•
Publication
33172468 | J:341531
First Author: Preuss C
Year: 2020
Journal: Mol Neurodegener
Title: A novel systems biology approach to evaluate mouse models of late-onset Alzheimer's disease.
Volume: 15
Issue: 1
Pages: 67
•
•
•
•
•
Publication
32320719 | J:311231
 
First Author: Kim YJ
Year: 2020
Journal: Exp Gerontol
Title: miR-16-5p is upregulated by amyloid β deposition in Alzheimer's disease models and induces neuronal cell apoptosis through direct targeting and suppression of BCL-2.
Volume: 136
Pages: 110954
•
•
•
•
•
Publication
36458522 | J:351744
First Author: Yelleswarapu NK
Year: 2022
Journal: Neurogastroenterol Motil
Title: 5xFAD mice do not have myenteric amyloidosis, dysregulation of neuromuscular transmission or gastrointestinal dysmotility.
Volume: 34
Issue: 12
Pages: e14439
•
•
•
•
•
Publication
26632816 | J:348419
First Author: Lu L
Year: 2015
Journal: PLoS One
Title: Transient Cerebral Ischemia Promotes Brain Mitochondrial Dysfunction and Exacerbates Cognitive Impairments in Young 5xFAD Mice.
Volume: 10
Issue: 12
Pages: e0144068
•
•
•
•
•
Publication
30918024 | J:348426
First Author: Julian MC
Year: 2019
Journal: J Biol Chem
Title: Nature-inspired design and evolution of anti-amyloid antibodies.
Volume: 294
Issue: 21
Pages: 8438-8451
•
•
•
•
•
Publication
30858603 | J:277515
First Author: Park H
Year: 2019
Journal: Nat Neurosci
Title: In vivo neuronal gene editing via CRISPR-Cas9 amphiphilic nanocomplexes alleviates deficits in mouse models of Alzheimer's disease.
Volume: 22
Issue: 4
Pages: 524-528
•
•
•
•
•
Publication
33675750 | J:311259
 
First Author: Desai AA
Year: 2021
Journal: J Biol Chem
Title: Rational affinity maturation of anti-amyloid antibodies with high conformational and sequence specificity.
Volume: 296
Pages: 100508
•
•
•
•
•
Publication
34277888 | J:311238
First Author: Kim TH
Year: 2021
Journal: Neurophotonics
Title: Concurrent OCT and OCT angiography of retinal neurovascular degeneration in the 5XFAD Alzheimer's disease mice.
Volume: 8
Issue: 3
Pages: 035002
•
•
•
•
•
Publication
33065553 | J:311239
First Author: Wang Y
Year: 2020
Journal: Aging (Albany NY)
Title: TREM2 ameliorates neuroinflammatory response and cognitive impairment via PI3K/AKT/FoxO3a signaling pathway in Alzheimer's disease mice.
Volume: 12
Issue: 20
Pages: 20862-20879
•
•
•
•
•
Publication
32703308 | J:311240
First Author: Liu Q
Year: 2020
Journal: Alzheimers Res Ther
Title: Intracranial alternating current stimulation facilitates neurogenesis in a mouse model of Alzheimer's disease.
Volume: 12
Issue: 1
Pages: 89
•
•
•
•
•
Publication
28729192 | J:351768
 
First Author: DeBay DR
Year: 2017
Journal: Brain Res
Title: Butyrylcholinesterase-knockout reduces fibrillar β-amyloid and conserves (18)FDG retention in 5XFAD mouse model of Alzheimer's disease.
Volume: 1671
Pages: 102-110
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom