|  Help  |  About  |  Contact Us

Search our database by keyword

- or -

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 201 to 273 out of 273 for Akt3

Category restricted to Publication (x)

<< First    < Previous  |  Next >    Last >>
0.017s

Categories

Category: Publication
« show all
Type Details Score
Publication
20395592 | J:172704
First Author: Carraway MS
Year: 2010
Journal: Circ Res
Title: Erythropoietin activates mitochondrial biogenesis and couples red cell mass to mitochondrial mass in the heart.
Volume: 106
Issue: 11
Pages: 1722-30
•
•
•
•
•
Publication
26921108 | J:254662
First Author: Larson-Casey JL
Year: 2016
Journal: Immunity
Title: Macrophage Akt1 Kinase-Mediated Mitophagy Modulates Apoptosis Resistance and Pulmonary Fibrosis.
Volume: 44
Issue: 3
Pages: 582-596
•
•
•
•
•
Publication
21532616 | J:177100
First Author: Saji M
Year: 2011
Journal: Oncogene
Title: Akt1 deficiency delays tumor progression, vascular invasion, and distant metastasis in a murine model of thyroid cancer.
Volume: 30
Issue: 42
Pages: 4307-15
•
•
•
•
•
Publication
19965668 | J:156831
First Author: Peng C
Year: 2010
Journal: Blood
Title: PTEN is a tumor suppressor in CML stem cells and BCR-ABL-induced leukemias in mice.
Volume: 115
Issue: 3
Pages: 626-35
•
•
•
•
•
Publication
20042722 | J:160279
First Author: Calamito M
Year: 2010
Journal: Blood
Title: Akt1 and Akt2 promote peripheral B-cell maturation and survival.
Volume: 115
Issue: 20
Pages: 4043-50
•
•
•
•
•
Publication
19622728 | J:152016
First Author: Di Lorenzo A
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Akt1 is critical for acute inflammation and histamine-mediated vascular leakage.
Volume: 106
Issue: 34
Pages: 14552-7
•
•
•
•
•
Publication
20354168 | J:160459
First Author: Juntilla MM
Year: 2010
Journal: Blood
Title: AKT1 and AKT2 maintain hematopoietic stem cell function by regulating reactive oxygen species.
Volume: 115
Issue: 20
Pages: 4030-8
•
•
•
•
•
Publication
16075056 | J:100143
First Author: Ackah E
Year: 2005
Journal: J Clin Invest
Title: Akt1/protein kinase Balpha is critical for ischemic and VEGF-mediated angiogenesis.
Volume: 115
Issue: 8
Pages: 2119-27
•
•
•
•
•
Publication
20856813 | J:165125
First Author: Goncalves MD
Year: 2010
Journal: PLoS One
Title: Akt deficiency attenuates muscle size and function but not the response to ActRIIB inhibition.
Volume: 5
Issue: 9
Pages: e12707
•
•
•
•
•
Publication
25253241 | J:216457
First Author: Koral K
Year: 2014
Journal: Am J Physiol Renal Physiol
Title: Akt recruits Dab2 to albumin endocytosis in the proximal tubule.
Volume: 307
Issue: 12
Pages: F1380-9
•
•
•
•
•
Publication
21784858 | J:176739
First Author: Maruyama S
Year: 2011
Journal: J Biol Chem
Title: Adiponectin ameliorates doxorubicin-induced cardiotoxicity through Akt protein-dependent mechanism.
Volume: 286
Issue: 37
Pages: 32790-800
•
•
•
•
•
Publication
24235146 | J:207185
First Author: Ju R
Year: 2014
Journal: J Biol Chem
Title: Angiopoietin-2 secretion by endothelial cell exosomes: regulation by the phosphatidylinositol 3-kinase (PI3K)/Akt/endothelial nitric oxide synthase (eNOS) and syndecan-4/syntenin pathways.
Volume: 289
Issue: 1
Pages: 510-9
•
•
•
•
•
Publication
19654415 | J:220952
First Author: Schleicher M
Year: 2009
Journal: Sci Signal
Title: The Akt1-eNOS axis illustrates the specificity of kinase-substrate relationships in vivo.
Volume: 2
Issue: 82
Pages: ra41
•
•
•
•
•
Publication
19293429 | J:259097
First Author: Wang CY
Year: 2009
Journal: Sci Signal
Title: Obesity increases vascular senescence and susceptibility to ischemic injury through chronic activation of Akt and mTOR.
Volume: 2
Issue: 62
Pages: ra11
•
•
•
•
•
Publication
19737566 | J:185258
First Author: Lin JE
Year: 2010
Journal: Gastroenterology
Title: The hormone receptor GUCY2C suppresses intestinal tumor formation by inhibiting AKT signaling.
Volume: 138
Issue: 1
Pages: 241-54
•
•
•
•
•
Publication
16904613 | J:112695
First Author: Phung TL
Year: 2006
Journal: Cancer Cell
Title: Pathological angiogenesis is induced by sustained Akt signaling and inhibited by rapamycin.
Volume: 10
Issue: 2
Pages: 159-70
•
•
•
•
•
Publication
20407209 | J:161466
First Author: Shimizu I
Year: 2010
Journal: J Clin Invest
Title: Excessive cardiac insulin signaling exacerbates systolic dysfunction induced by pressure overload in rodents.
Volume: 120
Issue: 5
Pages: 1506-14
•
•
•
•
•
Publication
25266363 | J:253993
First Author: Chatterjee M
Year: 2014
Journal: Circ Res
Title: Macrophage migration inhibitory factor limits activation-induced apoptosis of platelets via CXCR7-dependent Akt signaling.
Volume: 115
Issue: 11
Pages: 939-49
•
•
•
•
•
Publication
22824041 | J:188789
First Author: Yang KC
Year: 2012
Journal: J Mol Cell Cardiol
Title: Exercise training and PI3Kα-induced electrical remodeling is independent of cellular hypertrophy and Akt signaling.
Volume: 53
Issue: 4
Pages: 532-41
•
•
•
•
•
Publication
28911943 | J:257166
 
First Author: Roy R
Year: 2017
Journal: J Mol Cell Cardiol
Title: Heterozygous deletion of AKT1 rescues cardiac contractility, but not hypertrophy, in a mouse model of Noonan Syndrome with Multiple Lentigines.
Volume: 112
Pages: 83-90
•
•
•
•
•
Publication
24085786 | J:205053
First Author: Gibbons AV
Year: 2013
Journal: Cancer Res
Title: Intestinal GUCY2C prevents TGF-β secretion coordinating desmoplasia and hyperproliferation in colorectal cancer.
Volume: 73
Issue: 22
Pages: 6654-66
•
•
•
•
•
Publication
24126057 | J:206064
First Author: Tsen F
Year: 2013
Journal: Mol Cell Biol
Title: Extracellular heat shock protein 90 signals through subdomain II and the NPVY motif of LRP-1 receptor to Akt1 and Akt2: a circuit essential for promoting skin cell migration in vitro and wound healing in vivo.
Volume: 33
Issue: 24
Pages: 4947-59
•
•
•
•
•
Publication
33976210 | J:306337
First Author: Xing J
Year: 2021
Journal: Nat Commun
Title: Identification of poly(ADP-ribose) polymerase 9 (PARP9) as a noncanonical sensor for RNA virus in dendritic cells.
Volume: 12
Issue: 1
Pages: 2681
•
•
•
•
•
Publication
22209699 | J:181962
First Author: Conley-LaComb MK
Year: 2012
Journal: Am J Pathol
Title: PTEN regulates PDGF ligand switch for β-PDGFR signaling in prostate cancer.
Volume: 180
Issue: 3
Pages: 1017-27
•
•
•
•
•
Publication
12782654 | J:83741
First Author: Peng XD
Year: 2003
Journal: Genes Dev
Title: Dwarfism, impaired skin development, skeletal muscle atrophy, delayed bone development, and impeded adipogenesis in mice lacking Akt1 and Akt2.
Volume: 17
Issue: 11
Pages: 1352-65
•
•
•
•
•
Publication
21507933 | J:173766
First Author: Endersby R
Year: 2011
Journal: Cancer Res
Title: Nonredundant functions for Akt isoforms in astrocyte growth and gliomagenesis in an orthotopic transplantation model.
Volume: 71
Issue: 12
Pages: 4106-16
•
•
•
•
•
Publication
26709097 | J:295457
First Author: Xie X
Year: 2016
Journal: Obesity (Silver Spring)
Title: Tumor suppressor RIZ1 in obesity and the PI3K/AKT/mTOR pathway.
Volume: 24
Issue: 2
Pages: 389-97
•
•
•
•
•
Publication
31138602 | J:279045
First Author: Kircher DA
Year: 2019
Journal: Mol Cancer Res
Title: AKT1E17K Activates Focal Adhesion Kinase and Promotes Melanoma Brain Metastasis.
Volume: 17
Issue: 9
Pages: 1787-1800
•
•
•
•
•
Publication
16923802 | J:117197
First Author: Liu X
Year: 2006
Journal: J Biol Chem
Title: Quantitative analysis of anti-apoptotic function of Akt in Akt1 and Akt2 double knock-out mouse embryonic fibroblast cells under normal and stressed conditions.
Volume: 281
Issue: 42
Pages: 31380-8
•
•
•
•
•
Publication
24942865 | J:216002
First Author: Jin Q
Year: 2014
Journal: Carcinogenesis
Title: Transcriptional and posttranslational regulation of insulin-like growth factor binding protein-3 by Akt3.
Volume: 35
Issue: 10
Pages: 2232-43
•
•
•
•
•
Publication
26993778 | J:309336
First Author: Ji P
Year: 2016
Journal: Oncotarget
Title: Driver or passenger effects of augmented c-Myc and Cdc20 in gliomagenesis.
Volume: 7
Issue: 17
Pages: 23521-9
•
•
•
•
•
Publication
33921698 | J:314111
 
First Author: Kwa MQ
Year: 2021
Journal: Cells
Title: MRCKα Is Dispensable for Breast Cancer Development in the MMTV-PyMT Model.
Volume: 10
Issue: 4
•
•
•
•
•
Publication
30692211 | J:272998
First Author: Ouyang S
Year: 2019
Journal: J Immunol
Title: Akt-1 and Akt-2 Differentially Regulate the Development of Experimental Autoimmune Encephalomyelitis by Controlling Proliferation of Thymus-Derived Regulatory T Cells.
Volume: 202
Issue: 5
Pages: 1441-1452
•
•
•
•
•
Publication
25240046 | J:216614
First Author: Babaev VR
Year: 2014
Journal: J Lipid Res
Title: Macrophage deficiency of Akt2 reduces atherosclerosis in Ldlr null mice.
Volume: 55
Issue: 11
Pages: 2296-308
•
•
•
•
•
Publication
18218855 | J:133503
First Author: Li D
Year: 2008
Journal: Blood
Title: GSK3beta is a negative regulator of platelet function and thrombosis.
Volume: 111
Issue: 7
Pages: 3522-30
•
•
•
•
•
Publication
30443181 | J:286948
First Author: Baek HJ
Year: 2018
Journal: Int J Biol Sci
Title: Inhibition of AKT suppresses the initiation and progression of BRCA1-associated mammary tumors.
Volume: 14
Issue: 13
Pages: 1769-1781
•
•
•
•
•
Publication
14755341 | J:87588
First Author: Woulfe D
Year: 2004
Journal: J Clin Invest
Title: Defects in secretion, aggregation, and thrombus formation in platelets from mice lacking Akt2.
Volume: 113
Issue: 3
Pages: 441-50
•
•
•
•
•
Publication
29378301 | J:321696
First Author: Ock S
Year: 2018
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Connexin43 and zonula occludens-1 are targets of Akt in cardiomyocytes that correlate with cardiac contractile dysfunction in Akt deficient hearts.
Volume: 1864
Issue: 4 Pt A
Pages: 1183-1191
•
•
•
•
•
Publication
20705244 | J:163678
First Author: Lazorchak AS
Year: 2010
Journal: Mol Cell
Title: Sin1-mTORC2 suppresses rag and il7r gene expression through Akt2 in B cells.
Volume: 39
Issue: 3
Pages: 433-43
•
•
•
•
•
Publication
25416384 | J:227793
First Author: Tang H
Year: 2015
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Deficiency of Akt1, but not Akt2, attenuates the development of pulmonary hypertension.
Volume: 308
Issue: 2
Pages: L208-20
•
•
•
•
•
Publication
18042802 | J:131334
First Author: Wofford JA
Year: 2008
Journal: Blood
Title: IL-7 promotes Glut1 trafficking and glucose uptake via STAT5-mediated activation of Akt to support T-cell survival.
Volume: 111
Issue: 4
Pages: 2101-11
•
•
•
•
•
Publication
22678916 | J:187755
First Author: Chang X
Year: 2012
Journal: Eur J Immunol
Title: Sin1 regulates Treg-cell development but is not required for T-cell growth and proliferation.
Volume: 42
Issue: 6
Pages: 1639-47
•
•
•
•
•
Publication
25136137 | J:216407
First Author: Lee MY
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Endothelial Akt1 mediates angiogenesis by phosphorylating multiple angiogenic substrates.
Volume: 111
Issue: 35
Pages: 12865-70
•
•
•
•
•
Publication
26473496 | J:323790
First Author: Pauta M
Year: 2016
Journal: Hepatology
Title: Akt-mediated foxo1 inhibition is required for liver regeneration.
Volume: 63
Issue: 5
Pages: 1660-74
•
•
•
•
•
Publication
22927331 | J:212626
First Author: Borst O
Year: 2012
Journal: Circ Res
Title: The inflammatory chemokine CXC motif ligand 16 triggers platelet activation and adhesion via CXC motif receptor 6-dependent phosphatidylinositide 3-kinase/Akt signaling.
Volume: 111
Issue: 10
Pages: 1297-307
•
•
•
•
•
Publication
26654940 | J:302263
First Author: Franks SE
Year: 2016
Journal: Oncotarget
Title: Unique roles of Akt1 and Akt2 in IGF-IR mediated lung tumorigenesis.
Volume: 7
Issue: 3
Pages: 3297-316
•
•
•
•
•
Publication
24056770 | J:202319
First Author: Canaud G
Year: 2013
Journal: Nat Med
Title: AKT2 is essential to maintain podocyte viability and function during chronic kidney disease.
Volume: 19
Issue: 10
Pages: 1288-96
•
•
•
•
•
Publication
29133876 | J:257379
First Author: Protack CD
Year: 2017
Journal: Sci Rep
Title: Eph-B4 regulates adaptive venous remodeling to improve arteriovenous fistula patency.
Volume: 7
Issue: 1
Pages: 15386
•
•
•
•
•
Publication
22384056 | J:185303
First Author: Lin JE
Year: 2012
Journal: PLoS One
Title: GUCY2C opposes systemic genotoxic tumorigenesis by regulating AKT-dependent intestinal barrier integrity.
Volume: 7
Issue: 2
Pages: e31686
•
•
•
•
•
Publication
35357006 | J:358032
First Author: Percival CJ
Year: 2022
Journal: J Anat
Title: The genetic basis of neurocranial size and shape across varied lab mouse populations.
Volume: 241
Issue: 2
Pages: 211-229
•
•
•
•
•
Publication
25883023 | J:227240
First Author: Kofuji S
Year: 2015
Journal: Cancer Discov
Title: INPP4B Is a PtdIns(3,4,5)P3 Phosphatase That Can Act as a Tumor Suppressor.
Volume: 5
Issue: 7
Pages: 730-9
•
•
•
•
•
Publication
23749633 | J:204828
First Author: Qiao G
Year: 2013
Journal: J Immunol
Title: T cell activation threshold regulated by E3 ubiquitin ligase Cbl-b determines fate of inducible regulatory T cells.
Volume: 191
Issue: 2
Pages: 632-9
•
•
•
•
•
Publication
23345428 | J:194335
First Author: Yang ZF
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: GABP transcription factor is required for development of chronic myelogenous leukemia via its control of PRKD2.
Volume: 110
Issue: 6
Pages: 2312-7
•
•
•
•
•
Publication
29025710 | J:269229
First Author: Jin Y
Year: 2017
Journal: Arterioscler Thromb Vasc Biol
Title: Opposing Actions of AKT (Protein Kinase B) Isoforms in Vascular Smooth Muscle Injury and Therapeutic Response.
Volume: 37
Issue: 12
Pages: 2311-2321
•
•
•
•
•
Publication
27238637 | J:256770
First Author: Titchenell PM
Year: 2016
Journal: Cell Metab
Title: Direct Hepatocyte Insulin Signaling Is Required for Lipogenesis but Is Dispensable for the Suppression of Glucose Production.
Volume: 23
Issue: 6
Pages: 1154-1166
•
•
•
•
•
Publication
21633171 | J:175661
First Author: Espeillac C
Year: 2011
Journal: J Clin Invest
Title: S6 kinase 1 is required for rapamycin-sensitive liver proliferation after mouse hepatectomy.
Volume: 121
Issue: 7
Pages: 2821-32
•
•
•
•
•
Publication
22344295 | J:181642
First Author: Lu M
Year: 2012
Journal: Nat Med
Title: Insulin regulates liver metabolism in vivo in the absence of hepatic Akt and Foxo1.
Volume: 18
Issue: 3
Pages: 388-95
•
•
•
•
•
Publication
19500214 | J:150968
First Author: Jorgensen ND
Year: 2009
Journal: J Neurochem
Title: Phosphorylation of ATXN1 at Ser776 in the cerebellum.
Volume: 110
Issue: 2
Pages: 675-86
•
•
•
•
•
Publication
29899041 | J:264617
First Author: Dharmat R
Year: 2018
Journal: J Cell Biol
Title: SPATA7 maintains a novel photoreceptor-specific zone in the distal connecting cilium.
Volume: 217
Issue: 8
Pages: 2851-2865
•
•
•
•
•
Publication
22037765 | J:182721
First Author: Wan M
Year: 2012
Journal: Mol Cell Biol
Title: Loss of Akt1 in mice increases energy expenditure and protects against diet-induced obesity.
Volume: 32
Issue: 1
Pages: 96-106
•
•
•
•
•
Publication
35581352 | J:326260
First Author: Di Pietro C
Year: 2022
Journal: Exp Mol Med
Title: Recruitment of monocytes primed to express heme oxygenase-1 ameliorates pathological lung inflammation in cystic fibrosis.
Volume: 54
Issue: 5
Pages: 639-652
•
•
•
•
•
Publication
38367239 | J:350583
First Author: Gu X
Year: 2024
Journal: Cell Rep
Title: Macrophage-induced integrin signaling promotes Schlemm's canal formation to prevent intraocular hypertension and glaucomatous optic neuropathy.
Volume: 43
Issue: 2
Pages: 113799
•
•
•
•
•
Publication
35878016 | J:336519
 
First Author: Simoes DCM
Year: 2022
Journal: J Cell Biol
Title: An integrin axis induces IFN-β production in plasmacytoid dendritic cells.
Volume: 221
Issue: 9
•
•
•
•
•
Publication
25662011 | J:219885
First Author: Perry RJ
Year: 2015
Journal: Cell
Title: Hepatic acetyl CoA links adipose tissue inflammation to hepatic insulin resistance and type 2 diabetes.
Volume: 160
Issue: 4
Pages: 745-58
•
•
•
•
•
Publication
17141631 | J:129773
First Author: Boxer RB
Year: 2006
Journal: Cell Metab
Title: Isoform-specific requirement for Akt1 in the developmental regulation of cellular metabolism during lactation.
Volume: 4
Issue: 6
Pages: 475-90
•
•
•
•
•
Publication
23919516 | J:317850
 
First Author: Watson KL
Year: 2013
Journal: BMC Cancer
Title: Loss of Akt1 or Akt2 delays mammary tumor onset and suppresses tumor growth rate in MTB-IGFIR transgenic mice.
Volume: 13
Pages: 375
•
•
•
•
•
Publication
24126911 | J:204975
First Author: Rastogi R
Year: 2013
Journal: J Biol Chem
Title: Rapamycin induces mitogen-activated protein (MAP) kinase phosphatase-1 (MKP-1) expression through activation of protein kinase B and mitogen-activated protein kinase kinase pathways.
Volume: 288
Issue: 47
Pages: 33966-77
•
•
•
•
•
Publication
29444170 | J:258011
First Author: Weihbrecht K
Year: 2018
Journal: PLoS One
Title: Genotypic and phenotypic characterization of the Sdccag8Tn(sb-Tyr)2161B.CA1C2Ove mouse model.
Volume: 13
Issue: 2
Pages: e0192755
•
•
•
•
•
Publication
- | J:180503
     
First Author: Overbeek PA
Year: 2012
Journal: MGI Direct Data Submission
Title: Direct Data Submission 2012/02/16
•
•
•
•
•
Publication
25730471 | J:220886
First Author: Jeffery E
Year: 2015
Journal: Nat Cell Biol
Title: Rapid depot-specific activation of adipocyte precursor cells at the onset of obesity.
Volume: 17
Issue: 4
Pages: 376-85
•
•
•
•
•
Publication
28486106 | J:242576
First Author: Zhang S
Year: 2017
Journal: Cancer Cell
Title: Hippo Signaling Suppresses Cell Ploidy and Tumorigenesis through Skp2.
Volume: 31
Issue: 5
Pages: 669-684.e7
•
•
•
•
•
Publication
23028142 | J:188260
First Author: Chen CC
Year: 2012
Journal: Genes Dev
Title: Autocrine prolactin induced by the Pten-Akt pathway is required for lactation initiation and provides a direct link between the Akt and Stat5 pathways.
Volume: 26
Issue: 19
Pages: 2154-68
•
•
•
•
•
Publication
21821099 | J:184660
 
First Author: Kvajo M
Year: 2012
Journal: Neuroscience
Title: Avoiding mouse traps in schizophrenia genetics: lessons and promises from current and emerging mouse models.
Volume: 211
Pages: 136-64
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom