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Search results 201 to 300 out of 823 for Brca1

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Category: Publication
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Type Details Score
Publication
12915465 | J:85460
First Author: Yang Y
Year: 2003
Journal: Hum Mol Genet
Title: Aberrant splicing induced by missense mutations in BRCA1: clues from a humanized mouse model.
Volume: 12
Issue: 17
Pages: 2121-31
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Publication
10195418 | J:54149
First Author: Irminger-Finger I
Year: 1999
Journal: Biol Chem
Title: The functions of breast cancer susceptibility gene 1 (BRCA1) product and its associated proteins.
Volume: 380
Issue: 2
Pages: 117-28
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Publication
18588899 | J:168879
First Author: Sordet O
Year: 2008
Journal: J Mol Biol
Title: Hyperphosphorylation of RNA polymerase II in response to topoisomerase I cleavage complexes and its association with transcription- and BRCA1-dependent degradation of topoisomerase I.
Volume: 381
Issue: 3
Pages: 540-9
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Publication
9528852 | J:46396
First Author: Jensen DE
Year: 1998
Journal: Oncogene
Title: BAP1: a novel ubiquitin hydrolase which binds to the BRCA1 RING finger and enhances BRCA1-mediated cell growth suppression.
Volume: 16
Issue: 9
Pages: 1097-112
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Publication
35393420 | J:323627
First Author: Mateo F
Year: 2022
Journal: Nat Commun
Title: Modification of BRCA1-associated breast cancer risk by HMMR overexpression.
Volume: 13
Issue: 1
Pages: 1895
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Publication
22789542 | J:191013
First Author: Schlacher K
Year: 2012
Journal: Cancer Cell
Title: A distinct replication fork protection pathway connects Fanconi anemia tumor suppressors to RAD51-BRCA1/2.
Volume: 22
Issue: 1
Pages: 106-16
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Publication
23408054 | J:194529
First Author: Titus S
Year: 2013
Journal: Sci Transl Med
Title: Impairment of BRCA1-related DNA double-strand break repair leads to ovarian aging in mice and humans.
Volume: 5
Issue: 172
Pages: 172ra21
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Publication
23173005 | J:194081
First Author: Kumar P
Year: 2012
Journal: PLoS Genet
Title: Cooperativity of Rb, Brca1, and p53 in malignant breast cancer evolution.
Volume: 8
Issue: 11
Pages: e1003027
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Publication
27815389 | J:238429
First Author: Li M
Year: 2017
Journal: Cancer Res
Title: Chemopreventive Effects of ROS Targeting in a Murine Model of BRCA1-Deficient Breast Cancer.
Volume: 77
Issue: 2
Pages: 448-458
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Publication
16843262 | J:110942
First Author: Furuta S
Year: 2006
Journal: Cancer Cell
Title: Removal of BRCA1/CtIP/ZBRK1 repressor complex on ANG1 promoter leads to accelerated mammary tumor growth contributed by prominent vasculature.
Volume: 10
Issue: 1
Pages: 13-24
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Publication
25016020 | J:267154
First Author: Simhadri S
Year: 2014
Journal: J Biol Chem
Title: Male fertility defect associated with disrupted BRCA1-PALB2 interaction in mice.
Volume: 289
Issue: 35
Pages: 24617-29
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Publication
19015238 | J:145559
First Author: Wu J
Year: 2009
Journal: Mol Cell Biol
Title: Histone ubiquitination associates with BRCA1-dependent DNA damage response.
Volume: 29
Issue: 3
Pages: 849-60
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Publication
21187397 | J:169700
First Author: Goldberg MS
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Nanoparticle-mediated delivery of siRNA targeting Parp1 extends survival of mice bearing tumors derived from Brca1-deficient ovarian cancer cells.
Volume: 108
Issue: 2
Pages: 745-50
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Publication
34555355 | J:315842
First Author: Paes Dias M
Year: 2021
Journal: Mol Cell
Title: Loss of nuclear DNA ligase III reverts PARP inhibitor resistance in BRCA1/53BP1 double-deficient cells by exposing ssDNA gaps.
Volume: 81
Issue: 22
Pages: 4692-4708.e9
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Publication
27670884 | J:237991
First Author: Li M
Year: 2016
Journal: EMBO Rep
Title: 53BP1 ablation rescues genomic instability in mice expressing 'RING-less' BRCA1.
Volume: 17
Issue: 11
Pages: 1532-1541
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Publication
38537683 | J:347096
First Author: Yoshino Y
Year: 2024
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Knockout of Brca1-interacting factor Ola1 in female mice induces tumors with estrogen suppressible centrosome amplification.
Volume: 1870
Issue: 5
Pages: 167138
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Publication
20807817 | J:164207
First Author: Ibrahim N
Year: 2010
Journal: Cancer Res
Title: BRCA1-associated epigenetic regulation of p73 mediates an effector pathway for chemosensitivity in ovarian carcinoma.
Volume: 70
Issue: 18
Pages: 7155-65
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Publication
30590041 | J:270746
First Author: Tornillo G
Year: 2018
Journal: Cell Rep
Title: Dual Mechanisms of LYN Kinase Dysregulation Drive Aggressive Behavior in Breast Cancer Cells.
Volume: 25
Issue: 13
Pages: 3674-3692.e10
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Publication
30530501 | J:271222
First Author: Barazas M
Year: 2019
Journal: Cancer Res
Title: Radiosensitivity Is an Acquired Vulnerability of PARPi-Resistant BRCA1-Deficient Tumors.
Volume: 79
Issue: 3
Pages: 452-460
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Publication
30017478 | J:264231
First Author: Menghi F
Year: 2018
Journal: Cancer Cell
Title: The Tandem Duplicator Phenotype Is a Prevalent Genome-Wide Cancer Configuration Driven by Distinct Gene Mutations.
Volume: 34
Issue: 2
Pages: 197-210.e5
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Publication
23727112 | J:198413
First Author: Callen E
Year: 2013
Journal: Cell
Title: 53BP1 mediates productive and mutagenic DNA repair through distinct phosphoprotein interactions.
Volume: 153
Issue: 6
Pages: 1266-80
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Publication
15175241 | J:104490
First Author: Kitagawa R
Year: 2004
Journal: Genes Dev
Title: Phosphorylation of SMC1 is a critical downstream event in the ATM-NBS1-BRCA1 pathway.
Volume: 18
Issue: 12
Pages: 1423-38
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Publication
14654789 | J:87001
First Author: Aglipay JA
Year: 2003
Journal: Oncogene
Title: A member of the Pyrin family, IFI16, is a novel BRCA1-associated protein involved in the p53-mediated apoptosis pathway.
Volume: 22
Issue: 55
Pages: 8931-8
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Publication
11477095 | J:72374
First Author: Sarkisian CJ
Year: 2001
Journal: J Biol Chem
Title: Analysis of murine Brca2 reveals conservation of protein-protein interactions but differences in nuclear localization signals.
Volume: 276
Issue: 40
Pages: 37640-8
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Publication
15589157 | J:95016
First Author: Turner JM
Year: 2004
Journal: Curr Biol
Title: BRCA1, histone H2AX phosphorylation, and male meiotic sex chromosome inactivation.
Volume: 14
Issue: 23
Pages: 2135-42
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17493263 | J:160877
First Author: Herschkowitz JI
Year: 2007
Journal: Genome Biol
Title: Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors.
Volume: 8
Issue: 5
Pages: R76
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Publication
37815460 | J:342840
 
First Author: Zeng J
Year: 2023
Journal: Dis Model Mech
Title: A genetic mosaic mouse model illuminates the pre-malignant progression of basal-like breast cancer.
Volume: 16
Issue: 11
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9950212 | J:52011
First Author: Cressman VL
Year: 1999
Journal: Cell Growth Differ
Title: Mammary tumor formation in p53- and BRCA1-deficient mice.
Volume: 10
Issue: 1
Pages: 1-10
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16982732 | J:112932
First Author: Xing D
Year: 2006
Journal: Cancer Res
Title: A mouse model for the molecular characterization of brca1-associated ovarian carcinoma.
Volume: 66
Issue: 18
Pages: 8949-53
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Publication
27322743 | J:239966
First Author: Nolan E
Year: 2016
Journal: Nat Med
Title: RANK ligand as a potential target for breast cancer prevention in BRCA1-mutation carriers.
Volume: 22
Issue: 8
Pages: 933-9
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17212342 | J:119996
First Author: McCarthy A
Year: 2007
Journal: J Pathol
Title: A mouse model of basal-like breast carcinoma with metaplastic elements.
Volume: 211
Issue: 4
Pages: 389-98
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Publication
16849561 | J:112124
First Author: Shukla V
Year: 2006
Journal: Cancer Res
Title: Absence of the full-length breast cancer-associated gene-1 leads to increased expression of insulin-like growth factor signaling axis members.
Volume: 66
Issue: 14
Pages: 7151-7
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Publication
18394172 | J:206998
 
First Author: Wright MH
Year: 2008
Journal: Mol Cancer
Title: Molecular analysis reveals heterogeneity of mouse mammary tumors conditionally mutant for Brca1.
Volume: 7
Pages: 29
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Publication
34329741 | J:310245
 
First Author: Lee O
Year: 2021
Journal: Cancer Lett
Title: Selective progesterone receptor blockade prevents BRCA1-associated mouse mammary tumors through modulation of epithelial and stromal genes.
Volume: 520
Pages: 255-266
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17804718 | J:124885
First Author: Deeb KK
Year: 2007
Journal: Cancer Res
Title: Identification of an integrated SV40 T/t-antigen cancer signature in aggressive human breast, prostate, and lung carcinomas with poor prognosis.
Volume: 67
Issue: 17
Pages: 8065-80
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27923913 | J:259838
First Author: Martinez-Ruiz H
Year: 2016
Journal: Sci Signal
Title: A TGFβ-miR-182-BRCA1 axis controls the mammary differentiation hierarchy.
Volume: 9
Issue: 457
Pages: ra118
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27811360 | J:297700
First Author: Scott A
Year: 2016
Journal: Oncotarget
Title: p16INK4a suppresses BRCA1-deficient mammary tumorigenesis.
Volume: 7
Issue: 51
Pages: 84496-84507
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10942534 | J:74077
First Author: Bennett LM
Year: 2000
Journal: Mol Carcinog
Title: BRCA2-null embryonic survival is prolonged on the BALB/c genetic background.
Volume: 28
Issue: 3
Pages: 174-83
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15485917 | J:94114
First Author: Kim SS
Year: 2004
Journal: Mol Cell Biol
Title: Uterus hyperplasia and increased carcinogen-induced tumorigenesis in mice carrying a targeted mutation of the Chk2 phosphorylation site in Brca1.
Volume: 24
Issue: 21
Pages: 9498-507
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Publication
29877575 | J:268685
First Author: van de Ven M
Year: 2018
Journal: J Pathol
Title: BRCA1-associated mammary tumorigenesis is dependent on estrogen rather than progesterone signaling.
Volume: 246
Issue: 1
Pages: 41-53
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Publication
22396490 | J:185752
First Author: Rottenberg S
Year: 2012
Journal: Cancer Res
Title: Impact of intertumoral heterogeneity on predicting chemotherapy response of BRCA1-deficient mammary tumors.
Volume: 72
Issue: 9
Pages: 2350-61
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29203461 | J:257834
First Author: Liu H
Year: 2018
Journal: Cancer Discov
Title: Identifying and Targeting Sporadic Oncogenic Genetic Aberrations in Mouse Models of Triple-Negative Breast Cancer.
Volume: 8
Issue: 3
Pages: 354-369
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Publication
27454287 | J:237116
First Author: Drost R
Year: 2016
Journal: J Clin Invest
Title: BRCA1185delAG tumors may acquire therapy resistance through expression of RING-less BRCA1.
Volume: 126
Issue: 8
Pages: 2903-18
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Publication
32053991 | J:297946
 
First Author: Hámori L
Year: 2020
Journal: Int J Mol Sci
Title: Establishment and Characterization of a Brca1-/-, p53-/- Mouse Mammary Tumor Cell Line.
Volume: 21
Issue: 4
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Publication
20631063 | J:162234
First Author: Issaeva N
Year: 2010
Journal: Cancer Res
Title: 6-thioguanine selectively kills BRCA2-defective tumors and overcomes PARP inhibitor resistance.
Volume: 70
Issue: 15
Pages: 6268-76
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Publication
30443181 | J:286948
First Author: Baek HJ
Year: 2018
Journal: Int J Biol Sci
Title: Inhibition of AKT suppresses the initiation and progression of BRCA1-associated mammary tumors.
Volume: 14
Issue: 13
Pages: 1769-1781
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Publication
15563594 | J:94726
First Author: Wang RH
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: A requirement for breast-cancer-associated gene 1 (BRCA1) in the spindle checkpoint.
Volume: 101
Issue: 49
Pages: 17108-13
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Publication
19996295 | J:155810
First Author: Kim SS
Year: 2009
Journal: Cancer Res
Title: Impaired skin and mammary gland development and increased gamma-irradiation-induced tumorigenesis in mice carrying a mutation of S1152-ATM phosphorylation site in Brca1.
Volume: 69
Issue: 24
Pages: 9291-300
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Publication
29739757 | J:264253
First Author: Mahdi AH
Year: 2018
Journal: Cancer Res
Title: Evidence of Intertissue Differences in the DNA Damage Response and the Pro-oncogenic Role of NF-κB in Mice with Disengaged BRCA1-PALB2 Interaction.
Volume: 78
Issue: 14
Pages: 3969-3981
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Publication
34607954 | J:316847
 
First Author: He Y
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: BRCA1/Trp53 heterozygosity and replication stress drive esophageal cancer development in a mouse model.
Volume: 118
Issue: 41
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9171368 | J:40594
First Author: Ludwig T
Year: 1997
Journal: Genes Dev
Title: Targeted mutations of breast cancer susceptibility gene homologs in mice: lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos.
Volume: 11
Issue: 10
Pages: 1226-41
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Publication
18851829 | J:141108
First Author: Wang RH
Year: 2008
Journal: Mol Cell
Title: Interplay among BRCA1, SIRT1, and Survivin during BRCA1-associated tumorigenesis.
Volume: 32
Issue: 1
Pages: 11-20
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Publication
24332043 | J:207621
First Author: Perets R
Year: 2013
Journal: Cancer Cell
Title: Transformation of the fallopian tube secretory epithelium leads to high-grade serous ovarian cancer in Brca;Tp53;Pten models.
Volume: 24
Issue: 6
Pages: 751-65
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Publication
33854442 | J:306240
 
First Author: Yamaguchi H
Year: 2021
Journal: Front Physiol
Title: Alteration of DNA Damage Response Causes Cleft Palate.
Volume: 12
Pages: 649492
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26100884 | J:223738
First Author: Henneman L
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Selective resistance to the PARP inhibitor olaparib in a mouse model for BRCA1-deficient metaplastic breast cancer.
Volume: 112
Issue: 27
Pages: 8409-14
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Publication
11739404 | -
First Author: Ye Q
Year: 2001
Journal: J Cell Biol
Title: BRCA1-induced large-scale chromatin unfolding and allele-specific effects of cancer-predisposing mutations.
Volume: 155
Issue: 6
Pages: 911-21
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Publication
32051414 | J:286736
First Author: Paiano J
Year: 2020
Journal: Nat Commun
Title: ATM and PRDM9 regulate SPO11-bound recombination intermediates during meiosis.
Volume: 11
Issue: 1
Pages: 857
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19531582 | J:153169
First Author: Kouznetsova A
Year: 2009
Journal: J Cell Sci
Title: BRCA1-mediated chromatin silencing is limited to oocytes with a small number of asynapsed chromosomes.
Volume: 122
Issue: Pt 14
Pages: 2446-52
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10490643 | J:57853
First Author: Cressman VL
Year: 1999
Journal: Mol Cell Biol
Title: Growth retardation, DNA repair defects, and lack of spermatogenesis in BRCA1-deficient mice.
Volume: 19
Issue: 10
Pages: 7061-75
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27943283 | J:241796
First Author: van de Ven M
Year: 2017
Journal: J Pathol
Title: Prophylactic window therapy with the clinical poly(ADP-ribose) polymerase inhibitor olaparib delays BRCA1-deficient mammary tumour formation in mice.
Volume: 241
Issue: 4
Pages: 511-521
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8634697 | J:30135
First Author: Abel KJ
Year: 1995
Journal: Hum Mol Genet
Title: Mouse Brca1: localization sequence analysis and identification of evolutionarily conserved domains.
Volume: 4
Issue: 12
Pages: 2265-73
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24748377 | J:215184
First Author: Szabova L
Year: 2014
Journal: PLoS One
Title: Pathway-specific engineered mouse allograft models functionally recapitulate human serous epithelial ovarian cancer.
Volume: 9
Issue: 4
Pages: e95649
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21709021 | J:175080
First Author: Brown AD
Year: 2011
Journal: Mol Cell Biol
Title: A conditional mouse model for measuring the frequency of homologous recombination events in vivo in the absence of essential genes.
Volume: 31
Issue: 17
Pages: 3593-602
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27402769 | J:235157
First Author: Juvekar A
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Phosphoinositide 3-kinase inhibitors induce DNA damage through nucleoside depletion.
Volume: 113
Issue: 30
Pages: E4338-47
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17496925 | J:129624
First Author: Li W
Year: 2007
Journal: Oncogene
Title: A role of estrogen/ERalpha signaling in BRCA1-associated tissue-specific tumor formation.
Volume: 26
Issue: 51
Pages: 7204-12
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17318223 | J:139260
First Author: Wang X
Year: 2007
Journal: Cell Death Differ
Title: Haploinsufficiency of Parp1 accelerates Brca1-associated centrosome amplification, telomere shortening, genetic instability, apoptosis, and embryonic lethality.
Volume: 14
Issue: 5
Pages: 924-31
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35641483 | J:325281
First Author: Wang Q
Year: 2022
Journal: Nat Commun
Title: STING agonism reprograms tumor-associated macrophages and overcomes resistance to PARP inhibition in BRCA1-deficient models of breast cancer.
Volume: 13
Issue: 1
Pages: 3022
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24567396 | J:273896
First Author: Gorrini C
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Estrogen controls the survival of BRCA1-deficient cells via a PI3K-NRF2-regulated pathway.
Volume: 111
Issue: 12
Pages: 4472-7
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20145144 | J:157686
First Author: Zander SA
Year: 2010
Journal: Cancer Res
Title: Sensitivity and acquired resistance of BRCA1;p53-deficient mouse mammary tumors to the topoisomerase I inhibitor topotecan.
Volume: 70
Issue: 4
Pages: 1700-10
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21113097 | J:168730
First Author: Kim KY
Year: 2010
Journal: J Vet Sci
Title: Conditional knockout of brca1/2 and p53 in mouse ovarian surface epithelium: do they play a role in ovarian carcinogenesis?
Volume: 11
Issue: 4
Pages: 291-7
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29938573 | J:302615
First Author: Yeo SK
Year: 2018
Journal: Autophagy
Title: Improved efficacy of mitochondrial disrupting agents upon inhibition of autophagy in a mouse model of BRCA1-deficient breast cancer.
Volume: 14
Issue: 7
Pages: 1214-1225
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Publication
23880761 | J:317655
First Author: Wang S
Year: 2013
Journal: J Biol Chem
Title: Progesterone receptor A stability is mediated by glycogen synthase kinase-3β in the Brca1-deficient mammary gland.
Volume: 288
Issue: 36
Pages: 26265-26274
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Publication
27760317 | J:240753
First Author: Alavattam KG
Year: 2016
Journal: Cell Rep
Title: Elucidation of the Fanconi Anemia Protein Network in Meiosis and Its Function in the Regulation of Histone Modifications.
Volume: 17
Issue: 4
Pages: 1141-1157
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Publication
29996906 | J:289214
First Author: Wang C
Year: 2018
Journal: Breast Cancer Res
Title: Estrogen promotes estrogen receptor negative BRCA1-deficient tumor initiation and progression.
Volume: 20
Issue: 1
Pages: 74
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Publication
20046869 | J:155940
First Author: Clark-Knowles KV
Year: 2009
Journal: PLoS One
Title: Conditional inactivation of Brca1, p53 and Rb in mouse ovaries results in the development of leiomyosarcomas.
Volume: 4
Issue: 12
Pages: e8534
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25079327 | J:217096
First Author: Santos MA
Year: 2014
Journal: Nature
Title: DNA-damage-induced differentiation of leukaemic cells as an anti-cancer barrier.
Volume: 514
Issue: 7520
Pages: 107-11
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17700520 | J:132120
First Author: Maekawa T
Year: 2008
Journal: Oncogene
Title: ATF-2 controls transcription of Maspin and GADD45 alpha genes independently from p53 to suppress mammary tumors.
Volume: 27
Issue: 8
Pages: 1045-54
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Publication
24842372 | J:213733
First Author: Polato F
Year: 2014
Journal: J Exp Med
Title: CtIP-mediated resection is essential for viability and can operate independently of BRCA1.
Volume: 211
Issue: 6
Pages: 1027-36
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Publication
26575024 | J:280480
First Author: Mace TA
Year: 2015
Journal: Oncotarget
Title: Single agent BMS-911543 Jak2 inhibitor has distinct inhibitory effects on STAT5 signaling in genetically engineered mice with pancreatic cancer.
Volume: 6
Issue: 42
Pages: 44509-22
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30022158 | J:265299
First Author: Mirman Z
Year: 2018
Journal: Nature
Title: 53BP1-RIF1-shieldin counteracts DSB resection through CST- and Polα-dependent fill-in.
Volume: 560
Issue: 7716
Pages: 112-116
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
28552778 | J:243570
 
First Author: Liu KH
Year: 2017
Journal: Toxicol Appl Pharmacol
Title: The impact of Zearalenone on the meiotic progression and primordial follicle assembly during early oogenesis.
Volume: 329
Pages: 9-17
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Publication
23657012 | J:197442
First Author: Bowman-Colin C
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Palb2 synergizes with Trp53 to suppress mammary tumor formation in a model of inherited breast cancer.
Volume: 110
Issue: 21
Pages: 8632-7
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Publication
23319656 | J:193691
First Author: Keimpema E
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Nerve growth factor scales endocannabinoid signaling by regulating monoacylglycerol lipase turnover in developing cholinergic neurons.
Volume: 110
Issue: 5
Pages: 1935-40
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Publication
22346761 | J:183411
First Author: Fukuda T
Year: 2012
Journal: PLoS Genet
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