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Search results 201 to 300 out of 1236 for Cdkn2a

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Category: Publication
Type Details Score
Publication
First Author: Nishino J
Year: 2008
Journal: Cell
Title: Hmga2 promotes neural stem cell self-renewal in young but not old mice by reducing p16Ink4a and p19Arf Expression.
Volume: 135
Issue: 2
Pages: 227-39
Publication
First Author: Le O
Year: 2018
Journal: Stem Cell Reports
Title: INK4a/ARF Expression Impairs Neurogenesis in the Brain of Irradiated Mice.
Volume: 10
Issue: 6
Pages: 1721-1733
Publication
First Author: Burgess RJ
Year: 2022
Journal: Genes Dev
Title: Bmi1 suppresses protein synthesis and promotes proteostasis in hematopoietic stem cells.
Volume: 36
Issue: 15-16
Pages: 887-900
Publication
First Author: Tchougounova E
Year: 2007
Journal: Oncogene
Title: Loss of Arf causes tumor progression of PDGFB-induced oligodendroglioma.
Volume: 26
Issue: 43
Pages: 6289-96
Publication
First Author: van Oosterwijk JG
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Small mitochondrial Arf (smArf) protein corrects p53-independent developmental defects of Arf tumor suppressor-deficient mice.
Volume: 114
Issue: 28
Pages: 7420-7425
Publication
First Author: Rahrmann EP
Year: 2009
Journal: Cancer Res
Title: Identification of PDE4D as a proliferation promoting factor in prostate cancer using a Sleeping Beauty transposon-based somatic mutagenesis screen.
Volume: 69
Issue: 10
Pages: 4388-97
Publication
First Author: Sinha VC
Year: 2015
Journal: Mol Cancer Res
Title: A p53/ARF-dependent anticancer barrier activates senescence and blocks tumorigenesis without impacting apoptosis.
Volume: 13
Issue: 2
Pages: 231-8
Publication
First Author: Mullins CD
Year: 2013
Journal: PLoS One
Title: Germinal center B-cells resist transformation by Kras independently of tumor suppressor Arf.
Volume: 8
Issue: 6
Pages: e67941
Publication
First Author: Haston S
Year: 2023
Journal: Cancer Cell
Title: Clearance of senescent macrophages ameliorates tumorigenesis in KRAS-driven lung cancer.
Volume: 41
Issue: 7
Pages: 1242-1260.e6
Publication
First Author: Cordero FJ
Year: 2017
Journal: Mol Cancer Res
Title: Histone H3.3K27M Represses p16 to Accelerate Gliomagenesis in a Murine Model of DIPG.
Volume: 15
Issue: 9
Pages: 1243-1254
Publication
First Author: Aoyama K
Year: 2021
Journal: Leukemia
Title: PRC2 insufficiency causes p53-dependent dyserythropoiesis in myelodysplastic syndrome.
Volume: 35
Issue: 4
Pages: 1156-1165
Publication
First Author: Nishijo K
Year: 2009
Journal: Cancer Res
Title: Credentialing a preclinical mouse model of alveolar rhabdomyosarcoma.
Volume: 69
Issue: 7
Pages: 2902-11
Publication
First Author: Ko A
Year: 2023
Journal: Cancer Discov
Title: LZTR1 Mutation Mediates Oncogenesis through Stabilization of EGFR and AXL.
Volume: 13
Issue: 3
Pages: 702-723
Publication
First Author: Oristian KM
Year: 2018
Journal: Cancer Res
Title: Loss of MST/Hippo Signaling in a Genetically Engineered Mouse Model of Fusion-Positive Rhabdomyosarcoma Accelerates Tumorigenesis.
Volume: 78
Issue: 19
Pages: 5513-5520
Publication
First Author: Ma L
Year: 2017
Journal: PLoS One
Title: LSL-KrasG12D; LSL-Trp53R172H/+; Ink4flox/+; Ptf1/p48-Cre mice are an applicable model for locally invasive and metastatic pancreatic cancer.
Volume: 12
Issue: 5
Pages: e0176844
Publication
First Author: Sharpless NE
Year: 2005
Journal: Mutat Res
Title: INK4a/ARF: a multifunctional tumor suppressor locus.
Volume: 576
Issue: 1-2
Pages: 22-38
Publication
First Author: Shamma A
Year: 2009
Journal: Cancer Cell
Title: Rb Regulates DNA damage response and cellular senescence through E2F-dependent suppression of N-ras isoprenylation.
Volume: 15
Issue: 4
Pages: 255-69
Publication
First Author: Dovey JS
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Bmi1 is critical for lung tumorigenesis and bronchioalveolar stem cell expansion.
Volume: 105
Issue: 33
Pages: 11857-62
Publication
First Author: Russell JL
Year: 2006
Journal: Oncogene
Title: E2F1 suppresses skin carcinogenesis via the ARF-p53 pathway.
Volume: 25
Issue: 6
Pages: 867-76
Publication
First Author: Xie Y
Year: 2016
Journal: Oncotarget
Title: MMP7 interacts with ARF in nucleus to potentiate tumor microenvironments for prostate cancer progression in vivo.
Volume: 7
Issue: 30
Pages: 47609-47619
Publication
First Author: Xie Y
Year: 2017
Journal: Sci Rep
Title: Dysregulation of YAP by ARF Stimulated with Tea-derived Carbon Nanodots.
Volume: 7
Issue: 1
Pages: 16577
Publication  
First Author: Annunziata I
Year: 2013
Journal: Nat Commun
Title: Lysosomal NEU1 deficiency affects amyloid precursor protein levels and amyloid-β secretion via deregulated lysosomal exocytosis.
Volume: 4
Pages: 2734
Publication
First Author: Lin HK
Year: 2010
Journal: Nature
Title: Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence.
Volume: 464
Issue: 7287
Pages: 374-9
Publication
First Author: Treanor LM
Year: 2011
Journal: Blood
Title: Functional interactions between Lmo2, the Arf tumor suppressor, and Notch1 in murine T-cell malignancies.
Volume: 117
Issue: 20
Pages: 5453-62
Publication
First Author: Bailey SL
Year: 2008
Journal: Mol Cancer Res
Title: Tumor suppression by p53 in the absence of Atm.
Volume: 6
Issue: 7
Pages: 1185-92
Publication
First Author: Maynard MA
Year: 2014
Journal: Oncogene
Title: Bmi1 is required for tumorigenesis in a mouse model of intestinal cancer.
Volume: 33
Issue: 28
Pages: 3742-7
Publication
First Author: Tchougounova E
Year: 2009
Journal: Oncogene
Title: Sox5 can suppress platelet-derived growth factor B-induced glioma development in Ink4a-deficient mice through induction of acute cellular senescence.
Volume: 28
Issue: 12
Pages: 1537-48
Publication
First Author: Koss B
Year: 2020
Journal: Cancer Res
Title: Epigenetic Control of Cdkn2a.Arf Protects Tumor-Infiltrating Lymphocytes from Metabolic Exhaustion.
Volume: 80
Issue: 21
Pages: 4707-4719
Publication
First Author: Eggert T
Year: 2016
Journal: Cancer Cell
Title: Distinct Functions of Senescence-Associated Immune Responses in Liver Tumor Surveillance and Tumor Progression.
Volume: 30
Issue: 4
Pages: 533-547
Publication
First Author: Collier LS
Year: 2005
Journal: Nature
Title: Cancer gene discovery in solid tumours using transposon-based somatic mutagenesis in the mouse.
Volume: 436
Issue: 7048
Pages: 272-6
Publication
First Author: El Hajjar J
Year: 2019
Journal: Sci Rep
Title: Heterochromatic genome instability and neurodegeneration sharing similarities with Alzheimer's disease in old Bmi1+/- mice.
Volume: 9
Issue: 1
Pages: 594
Publication
First Author: Shreeram S
Year: 2006
Journal: J Exp Med
Title: Regulation of ATM/p53-dependent suppression of myc-induced lymphomas by Wip1 phosphatase.
Volume: 203
Issue: 13
Pages: 2793-9
Publication
First Author: Reimann M
Year: 2007
Journal: Blood
Title: The Myc-evoked DNA damage response accounts for treatment resistance in primary lymphomas in vivo.
Volume: 110
Issue: 8
Pages: 2996-3004
Publication
First Author: Kool J
Year: 2010
Journal: Cancer Res
Title: Insertional mutagenesis in mice deficient for p15Ink4b, p16Ink4a, p21Cip1, and p27Kip1 reveals cancer gene interactions and correlations with tumor phenotypes.
Volume: 70
Issue: 2
Pages: 520-31
Publication
First Author: Mair M
Year: 2010
Journal: Gastroenterology
Title: Signal transducer and activator of transcription 3 protects from liver injury and fibrosis in a mouse model of sclerosing cholangitis.
Volume: 138
Issue: 7
Pages: 2499-508
Publication
First Author: Sreedharan S
Year: 2017
Journal: Cancer Res
Title: Mouse Models of Pediatric Supratentorial High-grade Glioma Reveal How Cell-of-Origin Influences Tumor Development and Phenotype.
Volume: 77
Issue: 3
Pages: 802-812
Publication
First Author: Xie Y
Year: 2014
Journal: Mol Oncol
Title: Slug regulates E-cadherin repression via p19Arf in prostate tumorigenesis.
Volume: 8
Issue: 7
Pages: 1355-64
Publication
First Author: Dauch D
Year: 2016
Journal: Nat Med
Title: A MYC-aurora kinase A protein complex represents an actionable drug target in p53-altered liver cancer.
Volume: 22
Issue: 7
Pages: 744-53
Publication
First Author: Koss B
Year: 2013
Journal: Blood
Title: Requirement for antiapoptotic MCL-1 in the survival of BCR-ABL B-lineage acute lymphoblastic leukemia.
Volume: 122
Issue: 9
Pages: 1587-98
Publication
First Author: Voncken JW
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Rnf2 (Ring1b) deficiency causes gastrulation arrest and cell cycle inhibition.
Volume: 100
Issue: 5
Pages: 2468-73
Publication
First Author: Ross JL
Year: 2021
Journal: Brain
Title: Platelet-derived growth factor beta is a potent inflammatory driver in paediatric high-grade glioma.
Volume: 144
Issue: 1
Pages: 53-69
Publication
First Author: Balsitis S
Year: 2005
Journal: J Virol
Title: Examination of the pRb-dependent and pRb-independent functions of E7 in vivo.
Volume: 79
Issue: 17
Pages: 11392-402
Publication
First Author: Liu Y
Year: 2016
Journal: Nature
Title: Deletions linked to TP53 loss drive cancer through p53-independent mechanisms.
Volume: 531
Issue: 7595
Pages: 471-475
Publication
First Author: Manlove LS
Year: 2016
Journal: J Immunol
Title: Heterologous Vaccination and Checkpoint Blockade Synergize To Induce Antileukemia Immunity.
Volume: 196
Issue: 11
Pages: 4793-804
Publication
First Author: Owczarek TB
Year: 2017
Journal: Cancer Res
Title: ARF Confers a Context-Dependent Response to Chemotherapy in Muscle-Invasive Bladder Cancer.
Volume: 77
Issue: 4
Pages: 1035-1046
Publication
First Author: Bender AM
Year: 2010
Journal: Cancer Res
Title: Sleeping beauty-mediated somatic mutagenesis implicates CSF1 in the formation of high-grade astrocytomas.
Volume: 70
Issue: 9
Pages: 3557-65
Publication
First Author: Gromley A
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Transient expression of the Arf tumor suppressor during male germ cell and eye development in Arf-Cre reporter mice.
Volume: 106
Issue: 15
Pages: 6285-90
Publication
First Author: Prieto LI
Year: 2023
Journal: Cancer Cell
Title: Senescent alveolar macrophages promote early-stage lung tumorigenesis.
Volume: 41
Issue: 7
Pages: 1261-1275.e6
Publication
First Author: Remy E
Year: 2015
Journal: Cancer Res
Title: A Modeling Approach to Explain Mutually Exclusive and Co-Occurring Genetic Alterations in Bladder Tumorigenesis.
Volume: 75
Issue: 19
Pages: 4042-52
Publication
First Author: Collier LS
Year: 2009
Journal: Cancer Res
Title: Whole-body sleeping beauty mutagenesis can cause penetrant leukemia/lymphoma and rare high-grade glioma without associated embryonic lethality.
Volume: 69
Issue: 21
Pages: 8429-37
Publication
First Author: Lee JY
Year: 2010
Journal: Cell Stem Cell
Title: mTOR activation induces tumor suppressors that inhibit leukemogenesis and deplete hematopoietic stem cells after Pten deletion.
Volume: 7
Issue: 5
Pages: 593-605
Publication
First Author: Reimann M
Year: 2010
Journal: Cancer Cell
Title: Tumor stroma-derived TGF-beta limits myc-driven lymphomagenesis via Suv39h1-dependent senescence.
Volume: 17
Issue: 3
Pages: 262-72
Publication
First Author: Bruggeman SW
Year: 2005
Journal: Genes Dev
Title: Ink4a and Arf differentially affect cell proliferation and neural stem cell self-renewal in Bmi1-deficient mice.
Volume: 19
Issue: 12
Pages: 1438-43
Publication
First Author: Murphy DJ
Year: 2008
Journal: Cancer Cell
Title: Distinct thresholds govern Myc's biological output in vivo.
Volume: 14
Issue: 6
Pages: 447-57
Publication
First Author: Efeyan A
Year: 2009
Journal: PLoS One
Title: Limited role of murine ATM in oncogene-induced senescence and p53-dependent tumor suppression.
Volume: 4
Issue: 5
Pages: e5475
Publication
First Author: Swarbrick A
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Id1 cooperates with oncogenic Ras to induce metastatic mammary carcinoma by subversion of the cellular senescence response.
Volume: 105
Issue: 14
Pages: 5402-7
Publication
First Author: Kon N
Year: 2021
Journal: Cancer Res
Title: Robust p53 Stabilization Is Dispensable for Its Activation and Tumor Suppressor Function.
Volume: 81
Issue: 4
Pages: 935-944
Publication
First Author: Aydin IT
Year: 2012
Journal: Pigment Cell Melanoma Res
Title: Coat color dilution in mice because of inactivation of the melanoma antigen MART-1.
Volume: 25
Issue: 1
Pages: 37-46
Publication
First Author: Manlove LS
Year: 2015
Journal: J Immunol
Title: Adaptive Immunity to Leukemia Is Inhibited by Cross-Reactive Induced Regulatory T Cells.
Volume: 195
Issue: 8
Pages: 4028-37
Publication
First Author: Dorr C
Year: 2015
Journal: Mol Cancer Res
Title: Transposon Mutagenesis Screen Identifies Potential Lung Cancer Drivers and CUL3 as a Tumor Suppressor.
Volume: 13
Issue: 8
Pages: 1238-47
Publication
First Author: Rossi L
Year: 2012
Journal: Cell Stem Cell
Title: Less is more: unveiling the functional core of hematopoietic stem cells through knockout mice.
Volume: 11
Issue: 3
Pages: 302-17
Publication
First Author: Seehawer M
Year: 2018
Journal: Nature
Title: Necroptosis microenvironment directs lineage commitment in liver cancer.
Volume: 562
Issue: 7725
Pages: 69-75
Publication
First Author: Demidov ON
Year: 2012
Journal: Cell Death Differ
Title: Role of Gadd45a in Wip1-dependent regulation of intestinal tumorigenesis.
Volume: 19
Issue: 11
Pages: 1761-8
Publication
First Author: Zencak D
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Retinal degeneration depends on Bmi1 function and reactivation of cell cycle proteins.
Volume: 110
Issue: 7
Pages: E593-601
Publication  
First Author: Mosteiro L
Year: 2018
Journal: Aging Cell
Title: Senescence promotes in vivo reprogramming through p16INK4a and IL-6.
Volume: 17
Issue: 2
Publication
First Author: Shai A
Year: 2015
Journal: Cancer Res
Title: TP53 Silencing Bypasses Growth Arrest of BRAFV600E-Induced Lung Tumor Cells in a Two-Switch Model of Lung Tumorigenesis.
Volume: 75
Issue: 15
Pages: 3167-80
Publication
First Author: Vyazunova I
Year: 2014
Journal: PLoS One
Title: Sleeping Beauty mouse models identify candidate genes involved in gliomagenesis.
Volume: 9
Issue: 11
Pages: e113489
Publication
First Author: Jankovic M
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Role of the translocation partner in protection against AID-dependent chromosomal translocations.
Volume: 107
Issue: 1
Pages: 187-92
Publication
First Author: Mattison J
Year: 2010
Journal: Cancer Res
Title: Novel candidate cancer genes identified by a large-scale cross-species comparative oncogenomics approach.
Volume: 70
Issue: 3
Pages: 883-95
Publication
First Author: Ramiro AR
Year: 2006
Journal: Nature
Title: Role of genomic instability and p53 in AID-induced c-myc-Igh translocations.
Volume: 440
Issue: 7080
Pages: 105-9
Publication
First Author: Kang TW
Year: 2011
Journal: Nature
Title: Senescence surveillance of pre-malignant hepatocytes limits liver cancer development.
Volume: 479
Issue: 7374
Pages: 547-51
Publication
First Author: Zhu L
Year: 2016
Journal: Cell
Title: Multi-organ Mapping of Cancer Risk.
Volume: 166
Issue: 5
Pages: 1132-1146.e7
Publication
First Author: Wikenheiser-Brokamp KA
Year: 2006
Journal: Cell Mol Life Sci
Title: Retinoblastoma family proteins: insights gained through genetic manipulation of mice.
Volume: 63
Issue: 7-8
Pages: 767-80
Publication
First Author: Quelle DE
Year: 1995
Journal: Cell
Title: Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest.
Volume: 83
Issue: 6
Pages: 993-1000
Publication
First Author: Inoue K
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Induction of ARF tumor suppressor gene expression and cell cycle arrest by transcription factor DMP1.
Volume: 96
Issue: 7
Pages: 3993-8
Publication
First Author: Reef S
Year: 2006
Journal: Mol Cell
Title: A short mitochondrial form of p19ARF induces autophagy and caspase-independent cell death.
Volume: 22
Issue: 4
Pages: 463-75
Publication
First Author: Gressani KM
Year: 1998
Journal: Carcinogenesis
Title: Induction of mutations in Ki-ras and INK4a in liver tumors of mice exposed in utero to 3-methylcholanthrene.
Volume: 19
Issue: 6
Pages: 1045-52
Publication
First Author: Soloff EV
Year: 1996
Journal: Gene
Title: The 5'-flanking region of the E1 alpha form of the murine p16INK4a (MTS1) gene.
Volume: 180
Issue: 1-2
Pages: 213-5
Publication
First Author: Zhang Y
Year: 2001
Journal: Cell Growth Differ
Title: Control of p53 ubiquitination and nuclear export by MDM2 and ARF.
Volume: 12
Issue: 4
Pages: 175-86
Publication
First Author: Greenberg RA
Year: 1999
Journal: Cell
Title: Short dysfunctional telomeres impair tumorigenesis in the INK4a(delta2/3) cancer-prone mouse.
Volume: 97
Issue: 4
Pages: 515-25
Publication
First Author: Khoo CM
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Ink4a/Arf tumor suppressor does not modulate the degenerative conditions or tumor spectrum of the telomerase-deficient mouse.
Volume: 104
Issue: 10
Pages: 3931-6
Publication
First Author: Huijbers IJ
Year: 2006
Journal: Cancer Res
Title: An inducible mouse model of melanoma expressing a defined tumor antigen.
Volume: 66
Issue: 6
Pages: 3278-86
Publication
First Author: Carbonneau CL
Year: 2012
Journal: Blood
Title: Ionizing radiation-induced expression of INK4a/ARF in murine bone marrow-derived stromal cell populations interferes with bone marrow homeostasis.
Volume: 119
Issue: 3
Pages: 717-26
Publication
First Author: Moore LM
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: IGFBP2 is a candidate biomarker for Ink4a-Arf status and a therapeutic target for high-grade gliomas.
Volume: 106
Issue: 39
Pages: 16675-9
Publication  
First Author: Lv F
Year: 2020
Journal: Front Cell Dev Biol
Title: CDKN2a/p16 Antagonizes Hepatic Stellate Cell Activation and Liver Fibrosis by Modulating ROS Levels.
Volume: 8
Pages: 176
Publication
First Author: Oreff GL
Year: 2023
Journal: Sci Rep
Title: Immortalized murine tenocyte cells: a novel and innovative tool for tendon research.
Volume: 13
Issue: 1
Pages: 1566
Publication
First Author: Jeon HM
Year: 2008
Journal: Genes Dev
Title: Inhibitor of differentiation 4 drives brain tumor-initiating cell genesis through cyclin E and notch signaling.
Volume: 22
Issue: 15
Pages: 2028-33
Publication
First Author: Recio JA
Year: 2002
Journal: Cancer Res
Title: Ink4a/arf deficiency promotes ultraviolet radiation-induced melanomagenesis.
Volume: 62
Issue: 22
Pages: 6724-30
Publication
First Author: D'Amico M
Year: 2003
Journal: Cancer Res
Title: The role of Ink4a/Arf in ErbB2 mammary gland tumorigenesis.
Volume: 63
Issue: 12
Pages: 3395-402
Publication
First Author: Chin L
Year: 1999
Journal: Nature
Title: Essential role for oncogenic Ras in tumour maintenance.
Volume: 400
Issue: 6743
Pages: 468-72
Publication
First Author: Kozono D
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Dynamic epigenetic regulation of glioblastoma tumorigenicity through LSD1 modulation of MYC expression.
Volume: 112
Issue: 30
Pages: E4055-64
Publication
First Author: Ackermann J
Year: 2005
Journal: Cancer Res
Title: Metastasizing melanoma formation caused by expression of activated N-RasQ61K on an INK4a-deficient background.
Volume: 65
Issue: 10
Pages: 4005-11
Publication
First Author: Morrison JP
Year: 2007
Journal: Toxicol Pathol
Title: N-ethyl-N-nitrosourea (ENU)-induced meningiomatosis and meningioma in p16(INK4a)/p19(ARF) tumor suppressor gene-deficient mice.
Volume: 35
Issue: 6
Pages: 780-7
Publication  
First Author: Kim YC
Year: 2009
Journal: BMC Dev Biol
Title: Wnt4 is not sufficient to induce lobuloalveolar mammary development.
Volume: 9
Pages: 55
Publication  
First Author: Hao J
Year: 2009
Journal: BMC Gastroenterol
Title: Gastroesophageal reflux leads to esophageal cancer in a surgical model with mice.
Volume: 9
Pages: 59
Publication
First Author: Tolleson WH
Year: 2005
Journal: Arch Ophthalmol
Title: Spontaneous uveal amelanotic melanoma in transgenic Tyr-RAS+ Ink4a/Arf-/- mice.
Volume: 123
Issue: 8
Pages: 1088-94
Publication
First Author: Aghi M
Year: 2008
Journal: Oncogene
Title: Oncolytic herpes virus with defective ICP6 specifically replicates in quiescent cells with homozygous genetic mutations in p16.
Volume: 27
Issue: 30
Pages: 4249-54
Publication
First Author: Tang Y
Year: 2005
Journal: Cancer Res
Title: In vivo assessment of RAS-dependent maintenance of tumor angiogenesis by real-time magnetic resonance imaging.
Volume: 65
Issue: 18
Pages: 8324-30
Publication
First Author: Lewis BC
Year: 2003
Journal: Genes Dev
Title: The c-myc and PyMT oncogenes induce different tumor types in a somatic mouse model for pancreatic cancer.
Volume: 17
Issue: 24
Pages: 3127-38
Publication
First Author: Walker GJ
Year: 2011
Journal: J Invest Dermatol
Title: Superficial spreading-like melanoma in Arf(-/-)::Tyr-Nras(Q61K)::K14-Kitl mice: keratinocyte Kit ligand expression sufficient to "translocate" melanomas from dermis to epidermis.
Volume: 131
Issue: 6
Pages: 1384-7