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Search results 201 to 300 out of 347 for Cgas

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Category: Publication
Type Details Score
Publication      
First Author: Bona N
Year: 2023
Journal: Nat Struct Mol Biol
Title: Fanconi anemia DNA crosslink repair factors protect against LINE-1 retrotransposition during mouse development.
Publication
First Author: Tegtmeyer PK
Year: 2019
Journal: Nat Commun
Title: STING induces early IFN-β in the liver and constrains myeloid cell-mediated dissemination of murine cytomegalovirus.
Volume: 10
Issue: 1
Pages: 2830
Publication
First Author: Aden K
Year: 2018
Journal: J Exp Med
Title: ATG16L1 orchestrates interleukin-22 signaling in the intestinal epithelium via cGAS-STING.
Volume: 215
Issue: 11
Pages: 2868-2886
Publication
First Author: Ahn J
Year: 2018
Journal: Cancer Cell
Title: Extrinsic Phagocyte-Dependent STING Signaling Dictates the Immunogenicity of Dying Cells.
Volume: 33
Issue: 5
Pages: 862-873.e5
Publication
First Author: Yockey LJ
Year: 2016
Journal: Cell
Title: Vaginal Exposure to Zika Virus during Pregnancy Leads to Fetal Brain Infection.
Volume: 166
Issue: 5
Pages: 1247-1256.e4
Publication
First Author: Donnelly CR
Year: 2021
Journal: Nature
Title: STING controls nociception via type I interferon signalling in sensory neurons.
Volume: 591
Issue: 7849
Pages: 275-280
Publication
First Author: Hasan M
Year: 2015
Journal: Immunity
Title: Cytosolic Nuclease TREX1 Regulates Oligosaccharyltransferase Activity Independent of Nuclease Activity to Suppress Immune Activation.
Volume: 43
Issue: 3
Pages: 463-74
Publication
First Author: Lee D
Year: 2024
Journal: Nat Biomed Eng
Title: Synthetic cationic helical polypeptides for the stimulation of antitumour innate immune pathways in antigen-presenting cells.
Volume: 8
Issue: 5
Pages: 593-610
Publication
First Author: Zhou Y
Year: 2020
Journal: Immunity
Title: Blockade of the Phagocytic Receptor MerTK on Tumor-Associated Macrophages Enhances P2X7R-Dependent STING Activation by Tumor-Derived cGAMP.
Volume: 52
Issue: 2
Pages: 357-373.e9
Publication  
First Author: Louie A
Year: 2020
Journal: Infect Immun
Title: Secretion of c-di-AMP by Listeria monocytogenes Leads to a STING-Dependent Antibacterial Response during Enterocolitis.
Volume: 88
Issue: 12
Publication
First Author: Thackray LB
Year: 2018
Journal: Cell Rep
Title: Oral Antibiotic Treatment of Mice Exacerbates the Disease Severity of Multiple Flavivirus Infections.
Volume: 22
Issue: 13
Pages: 3440-3453.e6
Publication      
First Author: Luksch H
Year: 2019
Journal: J Allergy Clin Immunol
Title: STING-associated lung disease in mice relies on T cells but not type I interferon.
Publication
First Author: Tomac J
Year: 2021
Journal: Immunity
Title: Viral infection of the ovaries compromises pregnancy and reveals innate immune mechanisms protecting fertility.
Volume: 54
Issue: 7
Pages: 1478-1493.e6
Publication
First Author: Xu MM
Year: 2017
Journal: Immunity
Title: Dendritic Cells but Not Macrophages Sense Tumor Mitochondrial DNA for Cross-priming through Signal Regulatory Protein α Signaling.
Volume: 47
Issue: 2
Pages: 363-373.e5
Publication
First Author: Danielson M
Year: 2024
Journal: iScience
Title: Cytosolic bacterial pathogens activate TLR pathways in tumors that synergistically enhance STING agonist cancer therapies.
Volume: 27
Issue: 12
Pages: 111385
Publication
First Author: Banerjee I
Year: 2018
Journal: Immunity
Title: Gasdermin D Restrains Type I Interferon Response to Cytosolic DNA by Disrupting Ionic Homeostasis.
Volume: 49
Issue: 3
Pages: 413-426.e5
Publication
First Author: Rongvaux A
Year: 2014
Journal: Cell
Title: Apoptotic caspases prevent the induction of type I interferons by mitochondrial DNA.
Volume: 159
Issue: 7
Pages: 1563-77
Publication
First Author: Yang N
Year: 2022
Journal: Nat Commun
Title: Lung type II alveolar epithelial cells collaborate with CCR2+ inflammatory monocytes in host defense against poxvirus infection.
Volume: 13
Issue: 1
Pages: 1671
Publication  
First Author: Patel S
Year: 2021
Journal: Front Immunol
Title: cGAS-STING and MyD88 Pathways Synergize in Ly6Chi Monocyte to Promote Streptococcus pneumoniae-Induced Late-Stage Lung IFNγ Production.
Volume: 12
Pages: 699702
Publication
First Author: Zhou C
Year: 2020
Journal: Immunity
Title: Transfer of cGAMP into Bystander Cells via LRRC8 Volume-Regulated Anion Channels Augments STING-Mediated Interferon Responses and Anti-viral Immunity.
Volume: 52
Issue: 5
Pages: 767-781.e6
Publication
First Author: Köster S
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Mycobacterium tuberculosis is protected from NADPH oxidase and LC3-associated phagocytosis by the LCP protein CpsA.
Volume: 114
Issue: 41
Pages: E8711-E8720
Publication    
First Author: Piersma SJ
Year: 2020
Journal: Elife
Title: Virus infection is controlled by hematopoietic and stromal cell sensing of murine cytomegalovirus through STING.
Volume: 9
Publication
First Author: Burke TP
Year: 2020
Journal: Nat Microbiol
Title: Inflammasome-mediated antagonism of type I interferon enhances Rickettsia pathogenesis.
Volume: 5
Issue: 5
Pages: 688-696
Publication
First Author: Bennion BG
Year: 2020
Journal: Cell Rep
Title: STING Gain-of-Function Disrupts Lymph Node Organogenesis and Innate Lymphoid Cell Development in Mice.
Volume: 31
Issue: 11
Pages: 107771
Publication
First Author: de Queiroz NMGP
Year: 2021
Journal: Sci Rep
Title: MyD88-dependent BCG immunotherapy reduces tumor and regulates tumor microenvironment in bladder cancer murine model.
Volume: 11
Issue: 1
Pages: 15648
Publication
First Author: Swanson KV
Year: 2017
Journal: J Exp Med
Title: A noncanonical function of cGAMP in inflammasome priming and activation.
Volume: 214
Issue: 12
Pages: 3611-3626
Publication
First Author: Liu TT
Year: 2016
Journal: J Immunol
Title: LSm14A Plays a Critical Role in Antiviral Immune Responses by Regulating MITA Level in a Cell-Specific Manner.
Volume: 196
Issue: 12
Pages: 5101-11
Publication
First Author: Gopinath S
Year: 2018
Journal: Nat Microbiol
Title: Topical application of aminoglycoside antibiotics enhances host resistance to viral infections in a microbiota-independent manner.
Volume: 3
Issue: 5
Pages: 611-621
Publication  
First Author: Sweere JM
Year: 2019
Journal: Science
Title: Bacteriophage trigger antiviral immunity and prevent clearance of bacterial infection.
Volume: 363
Issue: 6434
Publication
First Author: Moretti J
Year: 2017
Journal: Cell
Title: STING Senses Microbial Viability to Orchestrate Stress-Mediated Autophagy of the Endoplasmic Reticulum.
Volume: 171
Issue: 4
Pages: 809-823.e13
Publication
First Author: Place DE
Year: 2020
Journal: PLoS Pathog
Title: Interferon inducible GBPs restrict Burkholderia thailandensis motility induced cell-cell fusion.
Volume: 16
Issue: 3
Pages: e1008364
Publication
First Author: Yu X
Year: 2016
Journal: Immunity
Title: Cross-Regulation of Two Type I Interferon Signaling Pathways in Plasmacytoid Dendritic Cells Controls Anti-malaria Immunity and Host Mortality.
Volume: 45
Issue: 5
Pages: 1093-1107
Publication
First Author: Karki R
Year: 2018
Journal: Cell
Title: IRF8 Regulates Transcription of Naips for NLRC4 Inflammasome Activation.
Volume: 173
Issue: 4
Pages: 920-933.e13
Publication
First Author: Yang C
Year: 2021
Journal: Nat Commun
Title: Chlamydia evasion of neutrophil host defense results in NLRP3 dependent myeloid-mediated sterile inflammation through the purinergic P2X7 receptor.
Volume: 12
Issue: 1
Pages: 5454
Publication      
First Author: Mouse Genome Informatics and the Europhenome Mouse Phenotyping Resource
Year: 2010
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from Europhenome
Publication      
First Author: Mutant Mouse Regional Resource Centers
Year: 2004
Journal: Unpublished
Title: Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC)
Publication
First Author: Blackshaw S
Year: 2004
Journal: PLoS Biol
Title: Genomic analysis of mouse retinal development.
Volume: 2
Issue: 9
Pages: E247
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication  
First Author: Chu L
Year: 2021
Journal: Front Immunol
Title: Perillaldehyde Inhibition of cGAS Reduces dsDNA-Induced Interferon Response.
Volume: 12
Pages: 655637
Publication
First Author: Cho MG
Year: 2024
Journal: Nature
Title: MRE11 liberates cGAS from nucleosome sequestration during tumorigenesis.
Volume: 625
Issue: 7995
Pages: 585-592
Publication    
First Author: Volkman HE
Year: 2019
Journal: Elife
Title: Tight nuclear tethering of cGAS is essential for preventing autoreactivity.
Volume: 8
Publication
First Author: Zhao C
Year: 2023
Journal: Immunity
Title: Polyamine metabolism controls B-to-Z DNA transition to orchestrate DNA sensor cGAS activity.
Volume: 56
Issue: 11
Pages: 2508-2522.e6
Publication
First Author: Lv G
Year: 2024
Journal: Nat Cell Biol
Title: mTORC2-driven chromatin cGAS mediates chemoresistance through epigenetic reprogramming in colorectal cancer.
Volume: 26
Issue: 9
Pages: 1585-1596
Publication
First Author: Song ZM
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: KAT5 acetylates cGAS to promote innate immune response to DNA virus.
Volume: 117
Issue: 35
Pages: 21568-21575
Publication
First Author: Watkinson RE
Year: 2015
Journal: PLoS Pathog
Title: TRIM21 Promotes cGAS and RIG-I Sensing of Viral Genomes during Infection by Antibody-Opsonized Virus.
Volume: 11
Issue: 10
Pages: e1005253
Publication
First Author: Fang L
Year: 2023
Journal: Cancer Cell
Title: Methionine restriction promotes cGAS activation and chromatin untethering through demethylation to enhance antitumor immunity.
Volume: 41
Issue: 6
Pages: 1118-1133.e12
Publication
First Author: Zhang Q
Year: 2020
Journal: Cell Res
Title: USP29 maintains the stability of cGAS and promotes cellular antiviral responses and autoimmunity.
Volume: 30
Issue: 10
Pages: 914-927
Publication  
First Author: Zou M
Year: 2022
Journal: Free Radic Biol Med
Title: Heterochromatin inhibits cGAS and STING during oxidative stress-induced retinal pigment epithelium and retina degeneration.
Volume: 178
Pages: 147-160
Publication
First Author: Ghosh A
Year: 2019
Journal: Immunity
Title: Oligoadenylate-Synthetase-Family Protein OASL Inhibits Activity of the DNA Sensor cGAS during DNA Virus Infection to Limit Interferon Production.
Volume: 50
Issue: 1
Pages: 51-63.e5
Publication
First Author: Herzner AM
Year: 2015
Journal: Nat Immunol
Title: Sequence-specific activation of the DNA sensor cGAS by Y-form DNA structures as found in primary HIV-1 cDNA.
Volume: 16
Issue: 10
Pages: 1025-33
Publication
First Author: Wang Y
Year: 2017
Journal: Immunity
Title: Inflammasome Activation Triggers Caspase-1-Mediated Cleavage of cGAS to Regulate Responses to DNA Virus Infection.
Volume: 46
Issue: 3
Pages: 393-404
Publication
First Author: Tan HY
Year: 2022
Journal: iScience
Title: cGAS and DDX41-STING mediated intrinsic immunity spreads intercellularly to promote neuroinflammation in SOD1 ALS model.
Volume: 25
Issue: 6
Pages: 104404
Publication  
First Author: Zheng Y
Year: 2018
Journal: EMBO J
Title: Zika virus elicits inflammation to evade antiviral response by cleaving cGAS via NS1-caspase-1 axis.
Volume: 37
Issue: 18
Publication
First Author: Huang ZF
Year: 2018
Journal: Cell Host Microbe
Title: Human Cytomegalovirus Protein UL31 Inhibits DNA Sensing of cGAS to Mediate Immune Evasion.
Volume: 24
Issue: 1
Pages: 69-80.e4
Publication
First Author: Seo GJ
Year: 2015
Journal: Cell Rep
Title: Akt Kinase-Mediated Checkpoint of cGAS DNA Sensing Pathway.
Volume: 13
Issue: 2
Pages: 440-9
Publication
First Author: Du M
Year: 2018
Journal: Science
Title: DNA-induced liquid phase condensation of cGAS activates innate immune signaling.
Volume: 361
Issue: 6403
Pages: 704-709
Publication  
First Author: Zhong L
Year: 2020
Journal: Cell Discov
Title: Phosphorylation of cGAS by CDK1 impairs self-DNA sensing in mitosis.
Volume: 6
Pages: 26
Publication  
First Author: Apel F
Year: 2021
Journal: Sci Signal
Title: The cytosolic DNA sensor cGAS recognizes neutrophil extracellular traps.
Volume: 14
Issue: 673
Publication
First Author: Guo Y
Year: 2019
Journal: J Immunol
Title: Cutting Edge: USP27X Deubiquitinates and Stabilizes the DNA Sensor cGAS to Regulate Cytosolic DNA-Mediated Signaling.
Volume: 203
Issue: 8
Pages: 2049-2054
Publication
First Author: Andreeva L
Year: 2017
Journal: Nature
Title: cGAS senses long and HMGB/TFAM-bound U-turn DNA by forming protein-DNA ladders.
Volume: 549
Issue: 7672
Pages: 394-398
Publication
First Author: Zhao Z
Year: 2020
Journal: Cell Rep
Title: Mn2+ Directly Activates cGAS and Structural Analysis Suggests Mn2+ Induces a Noncanonical Catalytic Synthesis of 2'3'-cGAMP.
Volume: 32
Issue: 7
Pages: 108053
Publication
First Author: Zhou W
Year: 2021
Journal: Mol Cell
Title: cGAS phase separation inhibits TREX1-mediated DNA degradation and enhances cytosolic DNA sensing.
Volume: 81
Issue: 4
Pages: 739-755.e7
Publication
First Author: Lian H
Year: 2018
Journal: Immunity
Title: The Zinc-Finger Protein ZCCHC3 Binds RNA and Facilitates Viral RNA Sensing and Activation of the RIG-I-like Receptors.
Volume: 49
Issue: 3
Pages: 438-448.e5
Publication
First Author: Zhang X
Year: 2014
Journal: Cell Rep
Title: The cytosolic DNA sensor cGAS forms an oligomeric complex with DNA and undergoes switch-like conformational changes in the activation loop.
Volume: 6
Issue: 3
Pages: 421-30
Publication
First Author: Eaglesham JB
Year: 2019
Journal: Nature
Title: Viral and metazoan poxins are cGAMP-specific nucleases that restrict cGAS-STING signalling.
Volume: 566
Issue: 7743
Pages: 259-263
Publication
First Author: Xiao TS
Year: 2013
Journal: Mol Cell
Title: The cGAS-STING pathway for DNA sensing.
Volume: 51
Issue: 2
Pages: 135-9
Publication
First Author: Xia P
Year: 2018
Journal: Immunity
Title: A Circular RNA Protects Dormant Hematopoietic Stem Cells from DNA Sensor cGAS-Mediated Exhaustion.
Volume: 48
Issue: 4
Pages: 688-701.e7
Publication
First Author: Liu ZS
Year: 2019
Journal: Nat Immunol
Title: G3BP1 promotes DNA binding and activation of cGAS.
Volume: 20
Issue: 1
Pages: 18-28
Publication
First Author: Kranzusch PJ
Year: 2015
Journal: Mol Cell
Title: Ancient Origin of cGAS-STING Reveals Mechanism of Universal 2',3' cGAMP Signaling.
Volume: 59
Issue: 6
Pages: 891-903
Publication
First Author: Man SM
Year: 2015
Journal: Nat Immunol
Title: The transcription factor IRF1 and guanylate-binding proteins target activation of the AIM2 inflammasome by Francisella infection.
Volume: 16
Issue: 5
Pages: 467-75
Publication
First Author: Lu C
Year: 2021
Journal: Cancer Cell
Title: DNA Sensing in Mismatch Repair-Deficient Tumor Cells Is Essential for Anti-tumor Immunity.
Volume: 39
Issue: 1
Pages: 96-108.e6
Publication
First Author: Mathur V
Year: 2017
Journal: Neuron
Title: Activation of the STING-Dependent Type I Interferon Response Reduces Microglial Reactivity and Neuroinflammation.
Volume: 96
Issue: 6
Pages: 1290-1302.e6