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Search results 201 to 300 out of 1071 for Fmr1

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Category: Publication
Type Details Score
Publication
First Author: Chaya T
Year: 2022
Journal: Hum Mol Genet
Title: Deficiency of the neurodevelopmental disorder-associated gene Cyfip2 alters the retinal ganglion cell properties and visual acuity.
Volume: 31
Issue: 4
Pages: 535-547
Publication
First Author: Dictenberg JB
Year: 2008
Journal: Dev Cell
Title: A direct role for FMRP in activity-dependent dendritic mRNA transport links filopodial-spine morphogenesis to fragile X syndrome.
Volume: 14
Issue: 6
Pages: 926-39
Publication
First Author: Li Z
Year: 2001
Journal: Nucleic Acids Res
Title: The fragile X mental retardation protein inhibits translation via interacting with mRNA.
Volume: 29
Issue: 11
Pages: 2276-83
Publication
First Author: Stetler A
Year: 2006
Journal: Hum Mol Genet
Title: Identification and characterization of the methyl arginines in the fragile X mental retardation protein Fmrp.
Volume: 15
Issue: 1
Pages: 87-96
Publication
First Author: Antar LN
Year: 2006
Journal: Mol Cell Neurosci
Title: Local functions for FMRP in axon growth cone motility and activity-dependent regulation of filopodia and spine synapses.
Volume: 32
Issue: 1-2
Pages: 37-48
Publication
First Author: Zhang M
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Fragile X mental retardation protein FMRP and the RNA export factor NXF2 associate with and destabilize Nxf1 mRNA in neuronal cells.
Volume: 104
Issue: 24
Pages: 10057-62
Publication  
First Author: Giampetruzzi A
Year: 2013
Journal: Mol Cell Neurosci
Title: FMRP and myelin protein expression in oligodendrocytes.
Volume: 56
Pages: 333-41
Publication
First Author: Lu R
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: The fragile X protein controls microtubule-associated protein 1B translation and microtubule stability in brain neuron development.
Volume: 101
Issue: 42
Pages: 15201-6
Publication
First Author: Bechara EG
Year: 2009
Journal: PLoS Biol
Title: A novel function for fragile X mental retardation protein in translational activation.
Volume: 7
Issue: 1
Pages: e16
Publication
First Author: Westmark CJ
Year: 2011
Journal: PLoS One
Title: Reversal of fragile X phenotypes by manipulation of AβPP/Aβ levels in Fmr1KO mice.
Volume: 6
Issue: 10
Pages: e26549
Publication
First Author: Muddashetty RS
Year: 2007
Journal: J Neurosci
Title: Dysregulated metabotropic glutamate receptor-dependent translation of AMPA receptor and postsynaptic density-95 mRNAs at synapses in a mouse model of fragile X syndrome.
Volume: 27
Issue: 20
Pages: 5338-48
Publication
First Author: Darnell JC
Year: 2009
Journal: Hum Mol Genet
Title: Discrimination of common and unique RNA-binding activities among Fragile X mental retardation protein paralogs.
Volume: 18
Issue: 17
Pages: 3164-77
Publication  
First Author: Ferron L
Year: 2014
Journal: Nat Commun
Title: Fragile X mental retardation protein controls synaptic vesicle exocytosis by modulating N-type calcium channel density.
Volume: 5
Pages: 3628
Publication
First Author: Ashley CT
Year: 1993
Journal: Nat Genet
Title: Human and murine FMR-1: alternative splicing and translational initiation downstream of the CGG-repeat.
Volume: 4
Issue: 3
Pages: 244-51
Publication
First Author: Comery TA
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Abnormal dendritic spines in fragile X knockout mice: maturation and pruning deficits.
Volume: 94
Issue: 10
Pages: 5401-4
Publication
First Author: Khandjian EW
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Biochemical evidence for the association of fragile X mental retardation protein with brain polyribosomal ribonucleoparticles.
Volume: 101
Issue: 36
Pages: 13357-62
Publication
First Author: Zalfa F
Year: 2007
Journal: Nat Neurosci
Title: A new function for the fragile X mental retardation protein in regulation of PSD-95 mRNA stability.
Volume: 10
Issue: 5
Pages: 578-87
Publication
First Author: Edbauer D
Year: 2010
Journal: Neuron
Title: Regulation of synaptic structure and function by FMRP-associated microRNAs miR-125b and miR-132.
Volume: 65
Issue: 3
Pages: 373-84
Publication
First Author: Darnell JC
Year: 2011
Journal: Cell
Title: FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism.
Volume: 146
Issue: 2
Pages: 247-61
Publication
First Author: Ascano M Jr
Year: 2012
Journal: Nature
Title: FMRP targets distinct mRNA sequence elements to regulate protein expression.
Volume: 492
Issue: 7429
Pages: 382-6
Publication
First Author: Derlig K
Year: 2013
Journal: PLoS One
Title: Identification and characterisation of Simiate, a novel protein linked to the fragile X syndrome.
Volume: 8
Issue: 12
Pages: e83007
Publication
First Author: Menon RP
Year: 2004
Journal: J Mol Biol
Title: The C terminus of fragile X mental retardation protein interacts with the multi-domain Ran-binding protein in the microtubule-organising centre.
Volume: 343
Issue: 1
Pages: 43-53
Publication
First Author: Hou L
Year: 2006
Journal: Neuron
Title: Dynamic translational and proteasomal regulation of fragile X mental retardation protein controls mGluR-dependent long-term depression.
Volume: 51
Issue: 4
Pages: 441-54
Publication
First Author: Lai D
Year: 2006
Journal: RNA
Title: The fragile X mental retardation protein interacts with a distinct mRNA nuclear export factor NXF2.
Volume: 12
Issue: 8
Pages: 1446-9
Publication
First Author: Ceman S
Year: 2000
Journal: Biochem Biophys Res Commun
Title: Identification of mouse YB1/p50 as a component of the FMRP-associated mRNP particle.
Volume: 279
Issue: 3
Pages: 904-8
Publication
First Author: Piazzon N
Year: 2008
Journal: J Biol Chem
Title: In vitro and in cellulo evidences for association of the survival of motor neuron complex with the fragile X mental retardation protein.
Volume: 283
Issue: 9
Pages: 5598-610
Publication
First Author: Brown MR
Year: 2010
Journal: Nat Neurosci
Title: Fragile X mental retardation protein controls gating of the sodium-activated potassium channel Slack.
Volume: 13
Issue: 7
Pages: 819-21
Publication
First Author: Wang H
Year: 2004
Journal: Hum Mol Genet
Title: Developmentally-programmed FMRP expression in oligodendrocytes: a potential role of FMRP in regulating translation in oligodendroglia progenitors.
Volume: 13
Issue: 1
Pages: 79-89
Publication
First Author: Alpatov R
Year: 2014
Journal: Cell
Title: A chromatin-dependent role of the fragile X mental retardation protein FMRP in the DNA damage response.
Volume: 157
Issue: 4
Pages: 869-81
Publication
First Author: Schütt J
Year: 2009
Journal: J Biol Chem
Title: Fragile X mental retardation protein regulates the levels of scaffold proteins and glutamate receptors in postsynaptic densities.
Volume: 284
Issue: 38
Pages: 25479-87
Publication
First Author: Qie S
Year: 2017
Journal: Nat Commun
Title: Fbxo4-mediated degradation of Fxr1 suppresses tumorigenesis in head and neck squamous cell carcinoma.
Volume: 8
Issue: 1
Pages: 1534
Publication
First Author: Rehage N
Year: 2018
Journal: Nat Commun
Title: Binding of NUFIP2 to Roquin promotes recognition and regulation of ICOS mRNA.
Volume: 9
Issue: 1
Pages: 299
Publication
First Author: Gantois I
Year: 2017
Journal: Nat Med
Title: Metformin ameliorates core deficits in a mouse model of fragile X syndrome.
Volume: 23
Issue: 6
Pages: 674-677
Publication
First Author: Kooy RF
Year: 1996
Journal: Am J Med Genet
Title: Transgenic mouse model for the fragile X syndrome.
Volume: 64
Issue: 2
Pages: 241-5
Publication
First Author: Kooy RF
Year: 2003
Journal: Trends Genet
Title: Of mice and the fragile X syndrome.
Volume: 19
Issue: 3
Pages: 148-54
Publication
First Author: Tang X
Year: 2023
Journal: Mol Brain
Title: FMRP binds Per1 mRNA and downregulates its protein expression in mice.
Volume: 16
Issue: 1
Pages: 33
Publication  
First Author: Reynolds KE
Year: 2021
Journal: J Neuroimmunol
Title: Converging purinergic and immune signaling pathways drive IL-6 secretion by Fragile X cortical astrocytes via STAT3.
Volume: 361
Pages: 577745
Publication
First Author: Cook D
Year: 2011
Journal: PLoS One
Title: Fragile X related protein 1 clusters with ribosomes and messenger RNAs at a subset of dendritic spines in the mouse hippocampus.
Volume: 6
Issue: 10
Pages: e26120
Publication  
First Author: Saré RM
Year: 2022
Journal: Front Neurosci
Title: Effects of Treatment With Hypnotics on Reduced Sleep Duration and Behavior Abnormalities in a Mouse Model of Fragile X Syndrome.
Volume: 16
Pages: 811528
Publication
First Author: Talbot ZN
Year: 2018
Journal: Neuron
Title: Normal CA1 Place Fields but Discoordinated Network Discharge in a Fmr1-Null Mouse Model of Fragile X Syndrome.
Volume: 97
Issue: 3
Pages: 684-697.e4
Publication
First Author: Kim H
Year: 2013
Journal: J Neurosci
Title: Impaired critical period plasticity in primary auditory cortex of fragile X model mice.
Volume: 33
Issue: 40
Pages: 15686-92
Publication  
First Author: Svalina MN
Year: 2021
Journal: eNeuro
Title: Hyperexcitability and Loss of Feedforward Inhibition Contribute to Aberrant Plasticity in the Fmr1KO Amygdala.
Volume: 8
Issue: 3
Publication
First Author: Segal M
Year: 2003
Journal: Brain Res
Title: Is fragile X mental retardation protein involved in activity-induced plasticity of dendritic spines?
Volume: 972
Issue: 1-2
Pages: 9-15
Publication
First Author: Selby L
Year: 2007
Journal: Neurosci Lett
Title: Major defects in neocortical GABAergic inhibitory circuits in mice lacking the fragile X mental retardation protein.
Volume: 412
Issue: 3
Pages: 227-32
Publication
First Author: Coulson RL
Year: 2024
Journal: iScience
Title: Translational modulator ISRIB alleviates synaptic and behavioral phenotypes in Fragile X syndrome.
Volume: 27
Issue: 4
Pages: 109259
Publication
First Author: Meredith RM
Year: 2007
Journal: Neuron
Title: Increased threshold for spike-timing-dependent plasticity is caused by unreliable calcium signaling in mice lacking fragile X gene FMR1.
Volume: 54
Issue: 4
Pages: 627-38
Publication
First Author: Pfeiffer BE
Year: 2007
Journal: J Neurosci
Title: Fragile X mental retardation protein induces synapse loss through acute postsynaptic translational regulation.
Volume: 27
Issue: 12
Pages: 3120-30
Publication
First Author: Zhan X
Year: 2020
Journal: Nat Commun
Title: FMRP(1-297)-tat restores ion channel and synaptic function in a model of Fragile X syndrome.
Volume: 11
Issue: 1
Pages: 2755
Publication  
First Author: He CX
Year: 2013
Journal: Neuroscience
Title: The trouble with spines in fragile X syndrome: density, maturity and plasticity.
Volume: 251
Pages: 120-8
Publication
First Author: Guo W
Year: 2012
Journal: Hum Mol Genet
Title: Inhibition of GSK3β improves hippocampus-dependent learning and rescues neurogenesis in a mouse model of fragile X syndrome.
Volume: 21
Issue: 3
Pages: 681-91
Publication
First Author: Shah S
Year: 2020
Journal: Cell Rep
Title: FMRP Control of Ribosome Translocation Promotes Chromatin Modifications and Alternative Splicing of Neuronal Genes Linked to Autism.
Volume: 30
Issue: 13
Pages: 4459-4472.e6
Publication
First Author: Arnett MT
Year: 2014
Journal: PLoS One
Title: Deficits in tactile learning in a mouse model of fragile X syndrome.
Volume: 9
Issue: 10
Pages: e109116
Publication
First Author: Ifrim MF
Year: 2022
Journal: Cell Rep
Title: Development of single-molecule ubiquitination mediated fluorescence complementation to visualize protein ubiquitination dynamics in dendrites.
Volume: 41
Issue: 7
Pages: 111658
Publication    
First Author: Li J
Year: 2020
Journal: Elife
Title: Defective memory engram reactivation underlies impaired fear memory recall in Fragile X syndrome.
Volume: 9
Publication
First Author: Gurney ME
Year: 2017
Journal: Sci Rep
Title: Multiple Behavior Phenotypes of the Fragile-X Syndrome Mouse Model Respond to Chronic Inhibition of Phosphodiesterase-4D (PDE4D).
Volume: 7
Issue: 1
Pages: 14653
Publication
First Author: Michalon A
Year: 2012
Journal: Neuron
Title: Chronic pharmacological mGlu5 inhibition corrects fragile X in adult mice.
Volume: 74
Issue: 1
Pages: 49-56
Publication
First Author: Kao DI
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Altered mRNA transport, docking, and protein translation in neurons lacking fragile X mental retardation protein.
Volume: 107
Issue: 35
Pages: 15601-6
Publication
First Author: Lim CS
Year: 2014
Journal: Genes Dev
Title: Pharmacological rescue of Ras signaling, GluA1-dependent synaptic plasticity, and learning deficits in a fragile X model.
Volume: 28
Issue: 3
Pages: 273-89
Publication
First Author: Griffiths KK
Year: 2020
Journal: FASEB J
Title: Inefficient thermogenic mitochondrial respiration due to futile proton leak in a mouse model of fragile X syndrome.
Volume: 34
Issue: 6
Pages: 7404-7426
Publication
First Author: Geng J
Year: 2023
Journal: Dev Cell
Title: Deregulation of ER-mitochondria contact formation and mitochondrial calcium homeostasis mediated by VDAC in fragile X syndrome.
Volume: 58
Issue: 7
Pages: 597-615.e10
Publication
First Author: Parrott JM
Year: 2021
Journal: iScience
Title: Altered inflammatory response in FMRP-deficient microglia.
Volume: 24
Issue: 11
Pages: 103293
Publication
First Author: Li J
Year: 2002
Journal: Mol Cell Neurosci
Title: Reduced cortical synaptic plasticity and GluR1 expression associated with fragile X mental retardation protein deficiency.
Volume: 19
Issue: 2
Pages: 138-51
Publication
First Author: Chuang SC
Year: 2005
Journal: J Neurosci
Title: Prolonged epileptiform discharges induced by altered group I metabotropic glutamate receptor-mediated synaptic responses in hippocampal slices of a fragile X mouse model.
Volume: 25
Issue: 35
Pages: 8048-55
Publication    
First Author: O'Donnell C
Year: 2017
Journal: Elife
Title: Beyond excitation/inhibition imbalance in multidimensional models of neural circuit changes in brain disorders.
Volume: 6
Publication
First Author: Oostra BA
Year: 1995
Journal: Bioessays
Title: A fragile gene.
Volume: 17
Issue: 11
Pages: 941-7
Publication
First Author: Gibson JM
Year: 2023
Journal: Cell Rep
Title: Cerebellar contribution to autism-relevant behaviors in fragile X syndrome models.
Volume: 42
Issue: 12
Pages: 113533
Publication
First Author: Hunsaker MR
Year: 2011
Journal: Behav Brain Res
Title: Motor deficits on a ladder rung task in male and female adolescent and adult CGG knock-in mice.
Volume: 222
Issue: 1
Pages: 117-21
Publication
First Author: Levenga J
Year: 2009
Journal: Neurobiol Dis
Title: Ultrastructural analysis of the functional domains in FMRP using primary hippocampal mouse neurons.
Volume: 35
Issue: 2
Pages: 241-50
Publication
First Author: Morales J
Year: 2002
Journal: Neuron
Title: Drosophila fragile X protein, DFXR, regulates neuronal morphology and function in the brain.
Volume: 34
Issue: 6
Pages: 961-72
Publication
First Author: Muddashetty RS
Year: 2011
Journal: Mol Cell
Title: Reversible inhibition of PSD-95 mRNA translation by miR-125a, FMRP phosphorylation, and mGluR signaling.
Volume: 42
Issue: 5
Pages: 673-88
Publication
First Author: Liu B
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Regulatory discrimination of mRNAs by FMRP controls mouse adult neural stem cell differentiation.
Volume: 115
Issue: 48
Pages: E11397-E11405
Publication
First Author: Baskaran S
Year: 2002
Journal: Genomics
Title: Instability of CGG repeats in transgenic mice.
Volume: 80
Issue: 2
Pages: 151-7
Publication
First Author: Deng PY
Year: 2022
Journal: Cell Rep
Title: FMRP regulates GABAA receptor channel activity to control signal integration in hippocampal granule cells.
Volume: 39
Issue: 7
Pages: 110820
Publication
First Author: Feuge J
Year: 2019
Journal: Cereb Cortex
Title: FMRP Modulates Activity-Dependent Spine Plasticity by Binding Cofilin1 mRNA and Regulating Localization and Local Translation.
Volume: 29
Issue: 12
Pages: 5204-5216
Publication    
First Author: Sawicka K
Year: 2019
Journal: Elife
Title: FMRP has a cell-type-specific role in CA1 pyramidal neurons to regulate autism-related transcripts and circadian memory.
Volume: 8
Publication
First Author: Dölen G
Year: 2007
Journal: Neuron
Title: Correction of fragile X syndrome in mice.
Volume: 56
Issue: 6
Pages: 955-62
Publication  
First Author: de Esch CE
Year: 2015
Journal: Neurobiol Dis
Title: Fragile X mice have robust mGluR5-dependent alterations of social behaviour in the Automated Tube Test.
Volume: 75
Pages: 31-9
Publication
First Author: Hwang JY
Year: 2022
Journal: Cell Rep
Title: CPEB3-dependent increase in GluA2 subunits impairs excitatory transmission onto inhibitory interneurons in a mouse model of fragile X.
Volume: 39
Issue: 10
Pages: 110853
Publication
First Author: Kumar V
Year: 2024
Journal: EMBO Mol Med
Title: mGluR7 allosteric modulator AMN082 corrects protein synthesis and pathological phenotypes in FXS.
Volume: 16
Issue: 3
Pages: 506-522
Publication
First Author: Janusz A
Year: 2013
Journal: J Neurosci
Title: The Fragile X mental retardation protein regulates matrix metalloproteinase 9 mRNA at synapses.
Volume: 33
Issue: 46
Pages: 18234-41
Publication
First Author: Zhao MG
Year: 2005
Journal: J Neurosci
Title: Deficits in trace fear memory and long-term potentiation in a mouse model for fragile X syndrome.
Volume: 25
Issue: 32
Pages: 7385-92
Publication
First Author: Pfeiffer BE
Year: 2010
Journal: Neuron
Title: Fragile X mental retardation protein is required for synapse elimination by the activity-dependent transcription factor MEF2.
Volume: 66
Issue: 2
Pages: 191-7
Publication
First Author: Mercaldo V
Year: 2023
Journal: Neuron
Title: Altered striatal actin dynamics drives behavioral inflexibility in a mouse model of fragile X syndrome.
Volume: 111
Issue: 11
Pages: 1760-1775.e8
Publication
First Author: Sidhu H
Year: 2014
Journal: J Neurosci
Title: Genetic removal of matrix metalloproteinase 9 rescues the symptoms of fragile X syndrome in a mouse model.
Volume: 34
Issue: 30
Pages: 9867-79
Publication  
First Author: Sethna F
Year: 2017
Journal: Nat Commun
Title: Enhanced expression of ADCY1 underlies aberrant neuronal signalling and behaviour in a syndromic autism model.
Volume: 8
Pages: 14359
Publication
First Author: Ronesi JA
Year: 2012
Journal: Nat Neurosci
Title: Disrupted Homer scaffolds mediate abnormal mGluR5 function in a mouse model of fragile X syndrome.
Volume: 15
Issue: 3
Pages: 431-40, S1
Publication
First Author: Lee HY
Year: 2011
Journal: Neuron
Title: Bidirectional regulation of dendritic voltage-gated potassium channels by the fragile X mental retardation protein.
Volume: 72
Issue: 4
Pages: 630-42
Publication
First Author: Yan QJ
Year: 2004
Journal: Genes Brain Behav
Title: A phenotypic and molecular characterization of the fmr1-tm1Cgr fragile X mouse.
Volume: 3
Issue: 6
Pages: 337-59
Publication
First Author: Ruggiero-Ruff RE
Year: 2023
Journal: Sci Rep
Title: Increased body weight in mice with fragile X messenger ribonucleoprotein 1 (Fmr1) gene mutation is associated with hypothalamic dysfunction.
Volume: 13
Issue: 1
Pages: 12666
Publication  
First Author: Felgerolle C
Year: 2019
Journal: Front Behav Neurosci
Title: Visual Behavior Impairments as an Aberrant Sensory Processing in the Mouse Model of Fragile X Syndrome.
Volume: 13
Pages: 228
Publication
First Author: Zupan B
Year: 2016
Journal: Genes Brain Behav
Title: Programming social behavior by the maternal fragile X protein.
Volume: 15
Issue: 6
Pages: 578-87
Publication  
First Author: Deng PY
Year: 2021
Journal: Front Mol Neurosci
Title: Hyperexcitability of Sensory Neurons in Fragile X Mouse Model.
Volume: 14
Pages: 796053
Publication
First Author: Jacquemont S
Year: 2018
Journal: Hum Mol Genet
Title: Protein synthesis levels are increased in a subset of individuals with fragile X syndrome.
Volume: 27
Issue: 12
Pages: 2039-2051
Publication
First Author: Cruz-Martín A
Year: 2010
Journal: J Neurosci
Title: Delayed stabilization of dendritic spines in fragile X mice.
Volume: 30
Issue: 23
Pages: 7793-803
Publication
First Author: Deosthale P
Year: 2023
Journal: Bone Res
Title: Fragile X Messenger Ribonucleoprotein 1 (FMR1), a novel inhibitor of osteoblast/osteocyte differentiation, regulates bone formation, mass, and strength in young and aged male and female mice.
Volume: 11
Issue: 1
Pages: 25
Publication
First Author: Spencer CM
Year: 2011
Journal: Autism Res
Title: Modifying behavioral phenotypes in Fmr1KO mice: genetic background differences reveal autistic-like responses.
Volume: 4
Issue: 1
Pages: 40-56
Publication  
First Author: Saré RM
Year: 2022
Journal: Front Neurosci
Title: Behavioral and Molecular Consequences of Chronic Sleep Restriction During Development in Fragile X Mice.
Volume: 16
Pages: 834890
Publication  
First Author: Rosenheck M
Year: 2021
Journal: Neurobiol Dis
Title: Effects of chronic inhibition of phosphodiesterase-4D on behavior and regional rates of cerebral protein synthesis in a mouse model of fragile X syndrome.
Volume: 159
Pages: 105485
Publication
First Author: Tyagi R
Year: 2023
Journal: ACS Pharmacol Transl Sci
Title: The Psychedelic N,N-Dipropyltryptamine Prevents Seizures in a Mouse Model of Fragile X Syndrome via a Mechanism that Appears Independent of Serotonin and Sigma1 Receptors.
Volume: 6
Issue: 10
Pages: 1480-1491
Publication
First Author: Krueger DD
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Cognitive dysfunction and prefrontal synaptic abnormalities in a mouse model of fragile X syndrome.
Volume: 108
Issue: 6
Pages: 2587-92