|  Help  |  About  |  Contact Us

Search our database by keyword

- or -

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 201 to 300 out of 848 for Htt

Category restricted to Publication (x)

<< First    < Previous  |  Next >    Last >>
0.023s

Categories

Category: Publication
« show all
Type Details Score
Publication
25461618 | J:231417
 
First Author: Yao J
Year: 2014
Journal: Mol Cell Neurosci
Title: Huntingtin is associated with cytomatrix proteins at the presynaptic terminal.
Volume: 63
Pages: 96-100
•
•
•
•
•
Publication
26048156 | J:227439
 
First Author: Swarnkar S
Year: 2015
Journal: Neurobiol Dis
Title: Ectopic expression of the striatal-enriched GTPase Rhes elicits cerebellar degeneration and an ataxia phenotype in Huntington's disease.
Volume: 82
Pages: 66-77
•
•
•
•
•
Publication
32681824 | J:301372
First Author: Lee H
Year: 2020
Journal: Neuron
Title: Cell Type-Specific Transcriptomics Reveals that Mutant Huntingtin Leads to Mitochondrial RNA Release and Neuronal Innate Immune Activation.
Volume: 107
Issue: 5
Pages: 891-908.e8
•
•
•
•
•
Publication
39068661 | J:353919
First Author: Callahan JW
Year: 2024
Journal: Cell Rep
Title: Movement-related increases in subthalamic activity optimize locomotion.
Volume: 43
Issue: 8
Pages: 114495
•
•
•
•
•
Publication
19525941 | J:152570
First Author: Morfini GA
Year: 2009
Journal: Nat Neurosci
Title: Pathogenic huntingtin inhibits fast axonal transport by activating JNK3 and phosphorylating kinesin.
Volume: 12
Issue: 7
Pages: 864-71
•
•
•
•
•
Publication
34469738 | J:324645
First Author: Goold R
Year: 2021
Journal: Cell Rep
Title: FAN1 controls mismatch repair complex assembly via MLH1 retention to stabilize CAG repeat expansion in Huntington's disease.
Volume: 36
Issue: 9
Pages: 109649
•
•
•
•
•
Publication
25446099 | J:220288
First Author: Choudhury KR
Year: 2015
Journal: Biochem Biophys Res Commun
Title: Chaperone protein HYPK interacts with the first 17 amino acid region of Huntingtin and modulates mutant HTT-mediated aggregation and cytotoxicity.
Volume: 456
Issue: 1
Pages: 66-73
•
•
•
•
•
Publication
18838463 | J:143295
First Author: Dietrich P
Year: 2009
Journal: Hum Mol Genet
Title: Congenital hydrocephalus associated with abnormal subcommissural organ in mice lacking huntingtin in Wnt1 cell lineages.
Volume: 18
Issue: 1
Pages: 142-50
•
•
•
•
•
Publication
32681165 | J:295993
First Author: Gerson JE
Year: 2020
Journal: Hum Mol Genet
Title: Ubiquilin-2 differentially regulates polyglutamine disease proteins.
Volume: 29
Issue: 15
Pages: 2596-2610
•
•
•
•
•
Publication
32242231 | J:288628
First Author: Jiang M
Year: 2020
Journal: Hum Mol Genet
Title: Nemo-like kinase reduces mutant huntingtin levels and mitigates Huntington's disease.
Volume: 29
Issue: 8
Pages: 1340-1352
•
•
•
•
•
Publication
17548833 | J:248257
First Author: Caviston JP
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Huntingtin facilitates dynein/dynactin-mediated vesicle transport.
Volume: 104
Issue: 24
Pages: 10045-50
•
•
•
•
•
Publication
19646509 | J:154511
First Author: Cho KJ
Year: 2009
Journal: Neuroscience
Title: Inhibition of apoptosis signal-regulating kinase 1 reduces endoplasmic reticulum stress and nuclear huntingtin fragments in a mouse model of Huntington disease.
Volume: 163
Issue: 4
Pages: 1128-34
•
•
•
•
•
Publication
21315254 | J:174750
First Author: Crook ZR
Year: 2011
Journal: Neuron
Title: Huntington's disease: can mice lead the way to treatment?
Volume: 69
Issue: 3
Pages: 423-35
•
•
•
•
•
Publication
27516062 | J:259936
 
First Author: Pan Y
Year: 2016
Journal: Sci Rep
Title: Inhibition of DNA Methyltransferases Blocks Mutant Huntingtin-Induced Neurotoxicity.
Volume: 6
Pages: 31022
•
•
•
•
•
Publication
28396396 | J:242134
First Author: Zhao Z
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Formation of neurodegenerative aggresome and death-inducing signaling complex in maternal diabetes-induced neural tube defects.
Volume: 114
Issue: 17
Pages: 4489-4494
•
•
•
•
•
Publication
21985783 | J:178446
First Author: Keryer G
Year: 2011
Journal: J Clin Invest
Title: Ciliogenesis is regulated by a huntingtin-HAP1-PCM1 pathway and is altered in Huntington disease.
Volume: 121
Issue: 11
Pages: 4372-82
•
•
•
•
•
Publication
31875875 | J:289016
First Author: Di Pardo A
Year: 2020
Journal: Hum Mol Genet
Title: Mutant huntingtin interacts with the sterol regulatory element-binding proteins and impairs their nuclear import.
Volume: 29
Issue: 3
Pages: 418-431
•
•
•
•
•
Publication
14981075 | J:219104
First Author: Gafni J
Year: 2004
Journal: J Biol Chem
Title: Inhibition of calpain cleavage of huntingtin reduces toxicity: accumulation of calpain/caspase fragments in the nucleus.
Volume: 279
Issue: 19
Pages: 20211-20
•
•
•
•
•
Publication
29212017 | J:254849
First Author: Hachigian LJ
Year: 2017
Journal: Cell Rep
Title: Control of Huntington's Disease-Associated Phenotypes by the Striatum-Enriched Transcription Factor Foxp2.
Volume: 21
Issue: 10
Pages: 2688-2695
•
•
•
•
•
Publication
23209424 | J:194172
First Author: Miller JP
Year: 2012
Journal: PLoS Genet
Title: A genome-scale RNA-interference screen identifies RRAS signaling as a pathologic feature of Huntington's disease.
Volume: 8
Issue: 11
Pages: e1003042
•
•
•
•
•
Publication
36914640 | J:338909
First Author: Pancani T
Year: 2023
Journal: Nat Commun
Title: Cholinergic deficits selectively boost cortical intratelencephalic control of striatum in male Huntington's disease model mice.
Volume: 14
Issue: 1
Pages: 1398
•
•
•
•
•
Publication
28550168 | J:243191
First Author: Louis Sam Titus ASC
Year: 2017
Journal: J Neurosci
Title: Reduced Expression of Foxp1 as a Contributing Factor in Huntington's Disease.
Volume: 37
Issue: 27
Pages: 6575-6587
•
•
•
•
•
Publication
32859226 | J:302806
First Author: de Souza JM
Year: 2020
Journal: Mol Brain
Title: mGluR5 regulates REST/NRSF signaling through N-cadherin/β-catenin complex in Huntington's disease.
Volume: 13
Issue: 1
Pages: 118
•
•
•
•
•
Publication
32876667 | J:298297
First Author: Loupe JM
Year: 2020
Journal: Hum Mol Genet
Title: Promotion of somatic CAG repeat expansion by Fan1 knock-out in Huntington's disease knock-in mice is blocked by Mlh1 knock-out.
Volume: 29
Issue: 18
Pages: 3044-3053
•
•
•
•
•
Publication
37580082 | J:352486
 
First Author: Voelkl K
Year: 2023
Journal: Life Sci Alliance
Title: Neuroprotective effects of hepatoma-derived growth factor in models of Huntington's disease.
Volume: 6
Issue: 11
•
•
•
•
•
Publication
25478910 | J:218852
First Author: Sanders SS
Year: 2015
Journal: Dev Biol
Title: Huntingtin interacting proteins 14 and 14-like are required for chorioallantoic fusion during early placental development.
Volume: 397
Issue: 2
Pages: 257-66
•
•
•
•
•
Publication
24991961 | J:224118
First Author: Plotkin JL
Year: 2014
Journal: Neuron
Title: Impaired TrkB receptor signaling underlies corticostriatal dysfunction in Huntington's disease.
Volume: 83
Issue: 1
Pages: 178-88
•
•
•
•
•
Publication
11152656 | J:67077
First Author: Näf D
Year: 2001
Journal: Hum Mol Genet
Title: Mouse models for the Wolf-Hirschhorn deletion syndrome.
Volume: 10
Issue: 2
Pages: 91-8
•
•
•
•
•
Publication
27721240 | J:239619
First Author: Rué L
Year: 2016
Journal: J Clin Invest
Title: Targeting CAG repeat RNAs reduces Huntington's disease phenotype independently of huntingtin levels.
Volume: 126
Issue: 11
Pages: 4319-4330
•
•
•
•
•
Publication
33086039 | J:300547
First Author: Yu X
Year: 2020
Journal: Neuron
Title: Context-Specific Striatal Astrocyte Molecular Responses Are Phenotypically Exploitable.
Volume: 108
Issue: 6
Pages: 1146-1162.e10
•
•
•
•
•
Publication
17500595 | J:121567
First Author: Kaltenbach LS
Year: 2007
Journal: PLoS Genet
Title: Huntingtin interacting proteins are genetic modifiers of neurodegeneration.
Volume: 3
Issue: 5
Pages: e82
•
•
•
•
•
Publication
36225731 | J:354504
 
First Author: Voelkl K
Year: 2022
Journal: Front Neurosci
Title: Distinct histological alterations of cortical interneuron types in mouse models of Huntington's disease.
Volume: 16
Pages: 1022251
•
•
•
•
•
Publication
8162057 | J:16635
First Author: Lin B
Year: 1994
Journal: Hum Mol Genet
Title: Sequence of the murine Huntington disease gene: evidence for conservation, alternate splicing and polymorphism in a triplet (CCG) repeat [corrected].
Volume: 3
Issue: 1
Pages: 85-92
•
•
•
•
•
Publication
8009370 | J:18404
First Author: Barnes GT
Year: 1994
Journal: Somat Cell Mol Genet
Title: Mouse Huntington's disease gene homolog (Hdh).
Volume: 20
Issue: 2
Pages: 87-97
•
•
•
•
•
Publication
7647777 | J:24940
First Author: Trottier Y
Year: 1995
Journal: Nat Genet
Title: Cellular localization of the Huntington's disease protein and discrimination of the normal and mutated form.
Volume: 10
Issue: 1
Pages: 104-10
•
•
•
•
•
Publication
7759106 | J:23247
First Author: Lin B
Year: 1995
Journal: Genomics
Title: Structural analysis of the 5' region of mouse and human Huntington disease genes reveals conservation of putative promoter region and di- and trinucleotide polymorphisms.
Volume: 25
Issue: 3
Pages: 707-15
•
•
•
•
•
Publication
9246489 | J:41317
 
First Author: MacDonald ME
Year: 1996
Journal: Cold Spring Harb Symp Quant Biol
Title: Targeted inactivation of the mouse Huntington's disease gene homolog Hdh.
Volume: 61
Pages: 627-38
•
•
•
•
•
Publication
11567051 | J:71624
First Author: Reiner A
Year: 2001
Journal: J Neurosci
Title: Neurons lacking huntingtin differentially colonize brain and survive in chimeric mice.
Volume: 21
Issue: 19
Pages: 7608-19
•
•
•
•
•
Publication
11062468 | J:65520
First Author: Dragatsis I
Year: 2000
Journal: Nat Genet
Title: Inactivation of Hdh in the brain and testis results in progressive neurodegeneration and sterility in mice.
Volume: 26
Issue: 3
Pages: 300-6
•
•
•
•
•
Publication
15935052 | J:99425
First Author: Brustovetsky N
Year: 2005
Journal: J Neurochem
Title: Age-dependent changes in the calcium sensitivity of striatal mitochondria in mouse models of Huntington's Disease.
Volume: 93
Issue: 6
Pages: 1361-70
•
•
•
•
•
Publication
10699173 | J:60937
First Author: Wheeler VC
Year: 2000
Journal: Hum Mol Genet
Title: Long glutamine tracts cause nuclear localization of a novel form of huntingtin in medium spiny striatal neurons in HdhQ92 and HdhQ111 knock-in mice.
Volume: 9
Issue: 4
Pages: 503-13
•
•
•
•
•
Publication
29324753 | J:257872
First Author: Langfelder P
Year: 2018
Journal: PLoS One
Title: MicroRNA signatures of endogenous Huntingtin CAG repeat expansion in mice.
Volume: 13
Issue: 1
Pages: e0190550
•
•
•
•
•
Publication
12895502 | J:128151
First Author: Snider BJ
Year: 2003
Journal: Neuroscience
Title: Neocortical neurons cultured from mice with expanded CAG repeats in the huntingtin gene: unaltered vulnerability to excitotoxins and other insults.
Volume: 120
Issue: 3
Pages: 617-25
•
•
•
•
•
Publication
26900923 | J:234512
First Author: Langfelder P
Year: 2016
Journal: Nat Neurosci
Title: Integrated genomics and proteomics define huntingtin CAG length-dependent networks in mice.
Volume: 19
Issue: 4
Pages: 623-33
•
•
•
•
•
Publication
16697652 | J:111237
First Author: Guidetti P
Year: 2006
Journal: Neurobiol Dis
Title: Elevated brain 3-hydroxykynurenine and quinolinate levels in Huntington disease mice.
Volume: 23
Issue: 1
Pages: 190-7
•
•
•
•
•
Publication
17519223 | J:142943
First Author: Kuhn A
Year: 2007
Journal: Hum Mol Genet
Title: Mutant huntingtin's effects on striatal gene expression in mice recapitulate changes observed in human Huntington's disease brain and do not differ with mutant huntingtin length or wild-type huntingtin dosage.
Volume: 16
Issue: 15
Pages: 1845-61
•
•
•
•
•
Publication
12460554 | J:125447
First Author: Namura S
Year: 2002
Journal: Neurobiol Dis
Title: The HD mutation does not alter neuronal death in the striatum of Hdh(Q92) knock-in mice after mild focal ischemia.
Volume: 11
Issue: 1
Pages: 147-54
•
•
•
•
•
Publication
19445966 | J:150366
First Author: Trueman RC
Year: 2009
Journal: Behav Brain Res
Title: Rule learning, visuospatial function and motor performance in the Hdh(Q92) knock-in mouse model of Huntington's disease.
Volume: 203
Issue: 2
Pages: 215-22
•
•
•
•
•
Publication
18367261 | J:133206
First Author: Trueman RC
Year: 2008
Journal: Behav Brain Res
Title: Time course of choice reaction time deficits in the Hdh(Q92) knock-in mouse model of Huntington's disease in the operant serial implicit learning task (SILT).
Volume: 189
Issue: 2
Pages: 317-24
•
•
•
•
•
Publication
17284197 | J:118627
First Author: Trueman RC
Year: 2007
Journal: Eur J Neurosci
Title: The operant serial implicit learning task reveals early onset motor learning deficits in the Hdh knock-in mouse model of Huntington's disease.
Volume: 25
Issue: 2
Pages: 551-8
•
•
•
•
•
Publication
26464483 | J:226832
First Author: Puigdellívol M
Year: 2015
Journal: Hum Mol Genet
Title: A role for Kalirin-7 in corticostriatal synaptic dysfunction in Huntington's disease.
Volume: 24
Issue: 25
Pages: 7265-85
•
•
•
•
•
Publication
21447599 | J:171983
First Author: Reis SA
Year: 2011
Journal: Hum Mol Genet
Title: Striatal neurons expressing full-length mutant huntingtin exhibit decreased N-cadherin and altered neuritogenesis.
Volume: 20
Issue: 12
Pages: 2344-55
•
•
•
•
•
Publication
37177784 | J:359526
First Author: O'Reilly D
Year: 2023
Journal: Mol Ther
Title: Di-valent siRNA-mediated silencing of MSH3 blocks somatic repeat expansion in mouse models of Huntington's disease.
Volume: 31
Issue: 6
Pages: 1661-1674
•
•
•
•
•
Publication
26143143 | J:231200
First Author: Cherubini M
Year: 2015
Journal: Biochim Biophys Acta
Title: Cdk5-mediated mitochondrial fission: A key player in dopaminergic toxicity in Huntington's disease.
Volume: 1852
Issue: 10 Pt A
Pages: 2145-60
•
•
•
•
•
Publication
24992836 | J:220144
 
First Author: Ribeiro M
Year: 2014
Journal: Free Radic Biol Med
Title: Insulin and IGF-1 improve mitochondrial function in a PI-3K/Akt-dependent manner and reduce mitochondrial generation of reactive oxygen species in Huntington's disease knock-in striatal cells.
Volume: 74
Pages: 129-44
•
•
•
•
•
Publication
29162692 | J:256508
First Author: Cariulo C
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Phosphorylation of huntingtin at residue T3 is decreased in Huntington's disease and modulates mutant huntingtin protein conformation.
Volume: 114
Issue: 50
Pages: E10809-E10818
•
•
•
•
•
Publication
22123819 | J:179665
First Author: Mochel F
Year: 2012
Journal: J Biol Chem
Title: Early alterations of brain cellular energy homeostasis in Huntington disease models.
Volume: 287
Issue: 2
Pages: 1361-70
•
•
•
•
•
Publication
11912178 | J:75831
First Author: Wheeler VC
Year: 2002
Journal: Hum Mol Genet
Title: Early phenotypes that presage late-onset neurodegenerative disease allow testing of modifiers in Hdh CAG knock-in mice.
Volume: 11
Issue: 6
Pages: 633-40
•
•
•
•
•
Publication
27217211 | J:235954
 
First Author: Du Z
Year: 2016
Journal: Neuroscience
Title: Early GABAergic transmission defects in the external globus pallidus and rest/activity rhythm alteration in a mouse model of Huntington's disease.
Volume: 329
Pages: 363-79
•
•
•
•
•
Publication
20383138 | J:159605
First Author: Martinez-Vicente M
Year: 2010
Journal: Nat Neurosci
Title: Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease.
Volume: 13
Issue: 5
Pages: 567-76
•
•
•
•
•
Publication
27163546 | J:236734
 
First Author: Yhnell E
Year: 2016
Journal: Exp Neurol
Title: Cognitive training modifies disease symptoms in a mouse model of Huntington's disease.
Volume: 282
Pages: 19-26
•
•
•
•
•
Publication
27196694 | J:249069
First Author: Bayram-Weston Z
Year: 2016
Journal: PLoS One
Title: Comparison of mHTT Antibodies in Huntington's Disease Mouse Models Reveal Specific Binding Profiles and Steady-State Ubiquitin Levels with Disease Development.
Volume: 11
Issue: 5
Pages: e0155834
•
•
•
•
•
Publication
23598407 | J:198508
 
First Author: Brito V
Year: 2013
Journal: Cell Death Dis
Title: Imbalance of p75(NTR)/TrkB protein expression in Huntington's disease: implication for neuroprotective therapies.
Volume: 4
Pages: e595
•
•
•
•
•
Publication
25449908 | J:218769
 
First Author: Tyebji S
Year: 2015
Journal: Neurobiol Dis
Title: Hyperactivation of D1 and A2A receptors contributes to cognitive dysfunction in Huntington's disease.
Volume: 74
Pages: 41-57
•
•
•
•
•
Publication
28453524 | J:247604
First Author: Coffey SR
Year: 2017
Journal: PLoS One
Title: Peripheral huntingtin silencing does not ameliorate central signs of disease in the B6.HttQ111/+ mouse model of Huntington's disease.
Volume: 12
Issue: 4
Pages: e0175968
•
•
•
•
•
Publication
28171658 | J:238625
First Author: Mao Y
Year: 2016
Journal: Hum Mol Genet
Title: Targeting TEAD/YAP-transcription-dependent necrosis, TRIAD, ameliorates Huntington's disease pathology.
Volume: 25
Issue: 21
Pages: 4749-4770
•
•
•
•
•
Publication
27701442 | J:251159
First Author: Yhnell E
Year: 2016
Journal: PLoS One
Title: A Longitudinal Operant Assessment of Cognitive and Behavioural Changes in the HdhQ111 Mouse Model of Huntington's Disease.
Volume: 11
Issue: 10
Pages: e0164072
•
•
•
•
•
Publication
24040016 | J:207349
First Author: Saavedra A
Year: 2013
Journal: PLoS One
Title: Regulation of hippocampal cGMP levels as a candidate to treat cognitive deficits in Huntington's disease.
Volume: 8
Issue: 9
Pages: e73664
•
•
•
•
•
Publication
30054496 | J:269619
First Author: Mueller KA
Year: 2018
Journal: Sci Rep
Title: Hippo Signaling Pathway Dysregulation in Human Huntington's Disease Brain and Neuronal Stem Cells.
Volume: 8
Issue: 1
Pages: 11355
•
•
•
•
•
Publication
29298414 | J:271716
First Author: Virlogeux A
Year: 2018
Journal: Cell Rep
Title: Reconstituting Corticostriatal Network on-a-Chip Reveals the Contribution of the Presynaptic Compartment to Huntington's Disease.
Volume: 22
Issue: 1
Pages: 110-122
•
•
•
•
•
Publication
22178857 | J:180131
First Author: Orvoen S
Year: 2012
Journal: Neurosci Lett
Title: Huntington's disease knock-in male mice show specific anxiety-like behaviour and altered neuronal maturation.
Volume: 507
Issue: 2
Pages: 127-32
•
•
•
•
•
Publication
29396492 | J:262558
First Author: Minnig S
Year: 2018
Journal: Sci Rep
Title: Early Detection of Apathetic Phenotypes in Huntington's Disease Knock-in Mice Using Open Source Tools.
Volume: 8
Issue: 1
Pages: 2304
•
•
•
•
•
Publication
12588797 | J:82117
First Author: Gines S
Year: 2003
Journal: Hum Mol Genet
Title: Specific progressive cAMP reduction implicates energy deficit in presymptomatic Huntington's disease knock-in mice.
Volume: 12
Issue: 5
Pages: 497-508
•
•
•
•
•
Publication
21840924 | J:176675
First Author: Fossale E
Year: 2011
Journal: Hum Mol Genet
Title: Differential effects of the Huntington's disease CAG mutation in striatum and cerebellum are quantitative not qualitative.
Volume: 20
Issue: 21
Pages: 4258-67
•
•
•
•
•
Publication
16687439 | J:112063
First Author: Lloret A
Year: 2006
Journal: Hum Mol Genet
Title: Genetic background modifies nuclear mutant huntingtin accumulation and HD CAG repeat instability in Huntington's disease knock-in mice.
Volume: 15
Issue: 12
Pages: 2015-24
•
•
•
•
•
Publication
11494364 | J:76017
First Author: Ishiguro H
Year: 2001
Journal: J Neurosci Res
Title: Age-dependent and tissue-specific CAG repeat instability occurs in mouse knock-in for a mutant Huntington's disease gene.
Volume: 65
Issue: 4
Pages: 289-97
•
•
•
•
•
Publication
28927719 | J:250587
 
First Author: Cao JK
Year: 2018
Journal: Behav Brain Res
Title: Sex-dependent behavioral impairments in the HdhQ350/+ mouse line.
Volume: 337
Pages: 34-45
•
•
•
•
•
Publication
25609071 | J:220868
First Author: Jin J
Year: 2015
Journal: Hum Mol Genet
Title: Early white matter abnormalities, progressive brain pathology and motor deficits in a novel knock-in mouse model of Huntington's disease.
Volume: 24
Issue: 9
Pages: 2508-27
•
•
•
•
•
Publication
11152661 | J:67074
First Author: Lin CH
Year: 2001
Journal: Hum Mol Genet
Title: Neurological abnormalities in a knock-in mouse model of Huntington's disease.
Volume: 10
Issue: 2
Pages: 137-44
•
•
•
•
•
Publication
7774020 | J:25941
First Author: Nasir J
Year: 1995
Journal: Cell
Title: Targeted disruption of the Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes.
Volume: 81
Issue: 5
Pages: 811-23
•
•
•
•
•
Publication
10082833 | J:53700
First Author: O'Kusky JR
Year: 1999
Journal: Brain Res
Title: Neuronal degeneration in the basal ganglia and loss of pallido-subthalamic synapses in mice with targeted disruption of the Huntington's disease gene.
Volume: 818
Issue: 2
Pages: 468-79
•
•
•
•
•
Publication
10196365 | J:54906
First Author: Shelbourne PF
Year: 1999
Journal: Hum Mol Genet
Title: A Huntington's disease CAG expansion at the murine Hdh locus is unstable and associated with behavioural abnormalities in mice.
Volume: 8
Issue: 5
Pages: 763-74
•
•
•
•
•
Publication
10196373 | J:54551
First Author: Usdin MT
Year: 1999
Journal: Hum Mol Genet
Title: Impaired synaptic plasticity in mice carrying the Huntington's disease mutation.
Volume: 8
Issue: 5
Pages: 839-46
•
•
•
•
•
Publication
17291464 | J:118624
 
First Author: Shelbourne P
Year: 2007
Journal: Brain Res
Title: Normal electrical properties of hippocampal neurons modelling early Huntington disease pathogenesis.
Volume: 1139
Pages: 226-34
•
•
•
•
•
Publication
14570710 | J:136414
First Author: Kennedy L
Year: 2003
Journal: Hum Mol Genet
Title: Dramatic tissue-specific mutation length increases are an early molecular event in Huntington disease pathogenesis.
Volume: 12
Issue: 24
Pages: 3359-67
•
•
•
•
•
Publication
10932179 | J:118556
First Author: Li H
Year: 2000
Journal: Nat Genet
Title: Amino-terminal fragments of mutant huntingtin show selective accumulation in striatal neurons and synaptic toxicity.
Volume: 25
Issue: 4
Pages: 385-9
•
•
•
•
•
Publication
15781041 | J:97469
First Author: Kennedy L
Year: 2005
Journal: Brain Res
Title: Alterations in dopamine and benzodiazepine receptor binding precede overt neuronal pathology in mice modelling early Huntington disease pathogenesis.
Volume: 1039
Issue: 1-2
Pages: 14-21
•
•
•
•
•
Publication
11606636 | J:72357
First Author: Li H
Year: 2001
Journal: J Neurosci
Title: Huntingtin aggregate-associated axonal degeneration is an early pathological event in Huntington's disease mice.
Volume: 21
Issue: 21
Pages: 8473-81
•
•
•
•
•
Publication
11030759 | J:65412
First Author: Kennedy L
Year: 2000
Journal: Hum Mol Genet
Title: Dramatic mutation instability in HD mouse striatum: does polyglutamine load contribute to cell-specific vulnerability in Huntington's disease?
Volume: 9
Issue: 17
Pages: 2539-44
•
•
•
•
•
Publication
23374344 | J:193455
First Author: Zala D
Year: 2013
Journal: Cell
Title: Vesicular glycolysis provides on-board energy for fast axonal transport.
Volume: 152
Issue: 3
Pages: 479-91
•
•
•
•
•
Publication
19074039 | J:143045
First Author: Her LS
Year: 2008
Journal: J Neurosci
Title: Enhanced sensitivity of striatal neurons to axonal transport defects induced by mutant huntingtin.
Volume: 28
Issue: 50
Pages: 13662-72
•
•
•
•
•
Publication
25748626 | J:224159
First Author: Mielcarek M
Year: 2015
Journal: PLoS Genet
Title: HDAC4-myogenin axis as an important marker of HD-related skeletal muscle atrophy.
Volume: 11
Issue: 3
Pages: e1005021
•
•
•
•
•
Publication
17715336 | J:123681
First Author: Heng MY
Year: 2007
Journal: J Neurosci
Title: Longitudinal evaluation of the Hdh(CAG)150 knock-in murine model of Huntington's disease.
Volume: 27
Issue: 34
Pages: 8989-98
•
•
•
•
•
Publication
38370446 | J:360609
First Author: Bondulich MK
Year: 2024
Journal: Brain Commun
Title: Translatable plasma and CSF biomarkers for use in mouse models of Huntington's disease.
Volume: 6
Issue: 1
Pages: fcae030
•
•
•
•
•
Publication
15200234 | J:90356
First Author: Dixon KT
Year: 2004
Journal: Gene Expr
Title: Mouse Huntington's disease homolog mRNA levels: variation and allele effects.
Volume: 11
Issue: 5-6
Pages: 221-31
•
•
•
•
•
Publication
20018729 | J:156460
First Author: Bradford J
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Expression of mutant huntingtin in mouse brain astrocytes causes age-dependent neurological symptoms.
Volume: 106
Issue: 52
Pages: 22480-5
•
•
•
•
•
Publication
23122961 | J:196344
First Author: Xun Z
Year: 2012
Journal: Cell Rep
Title: Targeting of XJB-5-131 to mitochondria suppresses oxidative DNA damage and motor decline in a mouse model of Huntington's disease.
Volume: 2
Issue: 5
Pages: 1137-42
•
•
•
•
•
Publication
26908614 | J:233020
First Author: Polyzos A
Year: 2016
Journal: Hum Mol Genet
Title: Mitochondrial targeting of XJB-5-131 attenuates or improves pathophysiology in HdhQ150 animals with well-developed disease phenotypes.
Volume: 25
Issue: 9
Pages: 1792-802
•
•
•
•
•
Publication
30930170 | J:275688
First Author: Polyzos AA
Year: 2019
Journal: Cell Metab
Title: Metabolic Reprogramming in Astrocytes Distinguishes Region-Specific Neuronal Susceptibility in Huntington Mice.
Volume: 29
Issue: 6
Pages: 1258-1273.e11
•
•
•
•
•
Publication
27568644 | J:256877
First Author: Toczek M
Year: 2016
Journal: Biochim Biophys Acta
Title: An impaired metabolism of nucleotides underpins a novel mechanism of cardiac remodeling leading to Huntington's disease related cardiomyopathy.
Volume: 1862
Issue: 11
Pages: 2147-2157
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom