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Search results 201 to 300 out of 659 for Jak2

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Category: Publication
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Type Details Score
Publication
24791858 | J:251766
First Author: Grundschober E
Year: 2014
Journal: Leukemia
Title: Acceleration of Bcr-Abl+ leukemia induced by deletion of JAK2.
Volume: 28
Issue: 9
Pages: 1918-22
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Publication
23264594 | J:194600
First Author: Kubovcakova L
Year: 2013
Journal: Blood
Title: Differential effects of hydroxyurea and INC424 on mutant allele burden and myeloproliferative phenotype in a JAK2-V617F polycythemia vera mouse model.
Volume: 121
Issue: 7
Pages: 1188-99
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Publication
24085768 | J:204599
First Author: Hobbs CM
Year: 2013
Journal: Blood
Title: JAK2V617F leads to intrinsic changes in platelet formation and reactivity in a knock-in mouse model of essential thrombocythemia.
Volume: 122
Issue: 23
Pages: 3787-97
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Publication
23863895 | J:202234
First Author: Hasan S
Year: 2013
Journal: Blood
Title: JAK2V617F expression in mice amplifies early hematopoietic cells and gives them a competitive advantage that is hampered by IFNα.
Volume: 122
Issue: 8
Pages: 1464-77
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Publication
30801958 | J:309461
First Author: Kilani B
Year: 2019
Journal: J Thromb Haemost
Title: Comparison of endothelial promoter efficiency and specificity in mice reveals a subset of Pdgfb-positive hematopoietic cells.
Volume: 17
Issue: 5
Pages: 827-840
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Publication
35011611 | J:333642
 
First Author: Buks R
Year: 2021
Journal: Cells
Title: Altered Ca(2+) Homeostasis in Red Blood Cells of Polycythemia Vera Patients Following Disturbed Organelle Sorting during Terminal Erythropoiesis.
Volume: 11
Issue: 1
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Publication
32045382 | J:315130
First Author: Poisson J
Year: 2020
Journal: J Clin Invest
Title: Erythrocyte-derived microvesicles induce arterial spasms in JAK2V617F myeloproliferative neoplasm.
Volume: 130
Issue: 5
Pages: 2630-2643
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Publication
36537918 | J:351549
First Author: Gurska LM
Year: 2023
Journal: Clin Cancer Res
Title: Crizotinib Has Preclinical Efficacy in Philadelphia-Negative Myeloproliferative Neoplasms.
Volume: 29
Issue: 5
Pages: 943-956
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Publication
36368558 | J:332183
     
First Author: Schönung M
Year: 2022
Journal: Exp Hematol
Title: Dynamic DNA methylation reveals novel cis-regulatory elements in mouse hematopoiesis.
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Publication
24951423 | J:214527
First Author: Lamrani L
Year: 2014
Journal: Blood
Title: Hemostatic disorders in a JAK2V617F-driven mouse model of myeloproliferative neoplasm.
Volume: 124
Issue: 7
Pages: 1136-45
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Publication
28728747 | J:244102
First Author: Erba BG
Year: 2017
Journal: Am J Pathol
Title: Endothelial-to-Mesenchymal Transition in Bone Marrow and Spleen of Primary Myelofibrosis.
Volume: 187
Issue: 8
Pages: 1879-1892
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Publication
10822380 | J:266148
First Author: Zochodne B
Year: 2000
Journal: Oncogene
Title: Epo regulates erythroid proliferation and differentiation through distinct signaling pathways: implication for erythropoiesis and Friend virus-induced erythroleukemia.
Volume: 19
Issue: 19
Pages: 2296-304
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Publication
7961995 | J:266144
First Author: Miura Y
Year: 1994
Journal: J Biol Chem
Title: Activation of the mitogen-activated protein kinase pathway by the erythropoietin receptor.
Volume: 269
Issue: 47
Pages: 29962-9
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Publication
8400282 | J:266153
First Author: Damen JE
Year: 1993
Journal: Blood
Title: Erythropoietin stimulates the tyrosine phosphorylation of Shc and its association with Grb2 and a 145-Kd tyrosine phosphorylated protein.
Volume: 82
Issue: 8
Pages: 2296-303
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Publication
16670266 | J:138073
First Author: Lacout C
Year: 2006
Journal: Blood
Title: JAK2V617F expression in murine hematopoietic cells leads to MPD mimicking human PV with secondary myelofibrosis.
Volume: 108
Issue: 5
Pages: 1652-60
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Publication
27406745 | J:240834
 
First Author: Bottos A
Year: 2016
Journal: Nat Commun
Title: Decreased NK-cell tumour immunosurveillance consequent to JAK inhibition enhances metastasis in breast cancer models.
Volume: 7
Pages: 12258
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Publication
31732720 | J:290132
First Author: Austin RJ
Year: 2020
Journal: Leukemia
Title: Distinct effects of ruxolitinib and interferon-alpha on murine JAK2V617F myeloproliferative neoplasm hematopoietic stem cell populations.
Volume: 34
Issue: 4
Pages: 1075-1089
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Publication
22627765 | J:189117
First Author: Mullally A
Year: 2012
Journal: Blood
Title: Distinct roles for long-term hematopoietic stem cells and erythroid precursor cells in a murine model of Jak2V617F-mediated polycythemia vera.
Volume: 120
Issue: 1
Pages: 166-72
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Publication
32017785 | J:285963
First Author: Staehle HF
Year: 2020
Journal: PLoS One
Title: Jmjd1c is dispensable for healthy adult hematopoiesis and Jak2V617F-driven myeloproliferative disease initiation in mice.
Volume: 15
Issue: 2
Pages: e0228362
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Publication
22371173 | J:231133
First Author: Akada H
Year: 2012
Journal: Haematologica
Title: Erythroid lineage-restricted expression of Jak2V617F is sufficient to induce a myeloproliferative disease in mice.
Volume: 97
Issue: 9
Pages: 1389-93
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Publication
11970898 | J:75970
First Author: Zabolotny JM
Year: 2002
Journal: Dev Cell
Title: PTP1B regulates leptin signal transduction in vivo.
Volume: 2
Issue: 4
Pages: 489-95
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Publication
29959151 | J:264287
First Author: Volker SE
Year: 2018
Journal: Cancer Res
Title: Cyclophilin A Function in Mammary Epithelium Impacts Jak2/Stat5 Signaling, Morphogenesis, Differentiation, and Tumorigenesis in the Mammary Gland.
Volume: 78
Issue: 14
Pages: 3877-3887
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Publication
30366920 | J:269934
First Author: Jacquelin S
Year: 2018
Journal: Blood
Title: Jak2V617F and Dnmt3a loss cooperate to induce myelofibrosis through activated enhancer-driven inflammation.
Volume: 132
Issue: 26
Pages: 2707-2721
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Publication
33041864 | J:312292
 
First Author: Stanly TA
Year: 2020
Journal: Front Physiol
Title: Quantitative Optical Diffraction Tomography Imaging of Mouse Platelets.
Volume: 11
Pages: 568087
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33075130 | J:307781
 
First Author: Dagher T
Year: 2021
Journal: J Exp Med
Title: JAK2V617F myeloproliferative neoplasm eradication by a novel interferon/arsenic therapy involves PML.
Volume: 218
Issue: 2
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Publication
30171023 | J:319322
First Author: Guy A
Year: 2019
Journal: Haematologica
Title: Vascular endothelial cell expression of JAK2V617F is sufficient to promote a pro-thrombotic state due to increased P-selectin expression.
Volume: 104
Issue: 1
Pages: 70-81
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Publication
17208428 | -
First Author: Ihle JN
Year: 2007
Journal: Curr Opin Genet Dev
Title: Jak2: normal function and role in hematopoietic disorders.
Volume: 17
Issue: 1
Pages: 8-14
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Publication
12370296 | J:79606
First Author: Carpino N
Year: 2002
Journal: Mol Cell Biol
Title: Identification, cDNA cloning, and targeted deletion of p70, a novel, ubiquitously expressed SH3 domain-containing protein.
Volume: 22
Issue: 21
Pages: 7491-500
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Publication
25572172 | J:222468
First Author: Kleppe M
Year: 2015
Journal: Cancer Discov
Title: JAK-STAT pathway activation in malignant and nonmalignant cells contributes to MPN pathogenesis and therapeutic response.
Volume: 5
Issue: 3
Pages: 316-31
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Publication
35439167 | J:325319
 
First Author: Yao JC
Year: 2022
Journal: J Clin Invest
Title: TGF-β signaling in myeloproliferative neoplasms contributes to myelofibrosis without disrupting the hematopoietic niche.
Volume: 132
Issue: 11
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Publication
29749399 | J:269488
     
First Author: Heaton WL
Year: 2018
Journal: Leukemia
Title: Autocrine Tnf signaling favors malignant cells in myelofibrosis in a Tnfr2-dependent fashion.
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Publication
21860020 | J:179034
First Author: Fleischman AG
Year: 2011
Journal: Blood
Title: TNFα facilitates clonal expansion of JAK2V617F positive cells in myeloproliferative neoplasms.
Volume: 118
Issue: 24
Pages: 6392-8
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Publication
27081096 | J:234798
First Author: Yang Y
Year: 2016
Journal: Blood
Title: Loss of Ezh2 cooperates with Jak2V617F in the development of myelofibrosis in a mouse model of myeloproliferative neoplasm.
Volume: 127
Issue: 26
Pages: 3410-23
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Publication
30423295 | J:266851
First Author: Celik H
Year: 2018
Journal: Cancer Cell
Title: JARID2 Functions as a Tumor Suppressor in Myeloid Neoplasms by Repressing Self-Renewal in Hematopoietic Progenitor Cells.
Volume: 34
Issue: 5
Pages: 741-756.e8
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Publication
26044284 | J:225602
First Author: Yan D
Year: 2015
Journal: Leukemia
Title: Deletion of Stat3 enhances myeloid cell expansion and increases the severity of myeloproliferative neoplasms in Jak2V617F knock-in mice.
Volume: 29
Issue: 10
Pages: 2050-61
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Publication
26650570 | J:233618
First Author: Wilson CG
Year: 2016
Journal: Endocrinology
Title: Hepatocyte-Specific Disruption of CD36 Attenuates Fatty Liver and Improves Insulin Sensitivity in HFD-Fed Mice.
Volume: 157
Issue: 2
Pages: 570-85
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27053299 | J:235077
First Author: Yue R
Year: 2016
Journal: Cell Stem Cell
Title: Leptin Receptor Promotes Adipogenesis and Reduces Osteogenesis by Regulating Mesenchymal Stromal Cells in Adult Bone Marrow.
Volume: 18
Issue: 6
Pages: 782-96
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Publication
23502961 | J:197988
First Author: Ramos P
Year: 2013
Journal: Nat Med
Title: Macrophages support pathological erythropoiesis in polycythemia vera and β-thalassemia.
Volume: 19
Issue: 4
Pages: 437-45
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Publication
35365653 | J:323886
First Author: Saleiro D
Year: 2022
Journal: Nat Commun
Title: Discovery of a signaling feedback circuit that defines interferon responses in myeloproliferative neoplasms.
Volume: 13
Issue: 1
Pages: 1750
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Publication
28334068 | J:242251
First Author: Franquinho F
Year: 2017
Journal: Cereb Cortex
Title: The Dyslexia-susceptibility Protein KIAA0319 Inhibits Axon Growth Through Smad2 Signaling.
Volume: 27
Issue: 3
Pages: 1732-1747
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Publication
36005555 | J:337769
First Author: Shi Z
Year: 2023
Journal: Haematologica
Title: ASXL1 mutations accelerate bone marrow fibrosis via EGR1-TNFA axis-mediated neoplastic fibrocyte generation in myeloproliferative neoplasms.
Volume: 108
Issue: 5
Pages: 1359-1373
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Publication
25281607 | J:220795
First Author: Chen E
Year: 2015
Journal: Blood
Title: Distinct effects of concomitant Jak2V617F expression and Tet2 loss in mice promote disease progression in myeloproliferative neoplasms.
Volume: 125
Issue: 2
Pages: 327-35
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Publication
29991556 | J:266048
First Author: Shepherd MS
Year: 2018
Journal: Blood
Title: Single-cell approaches identify the molecular network driving malignant hematopoietic stem cell self-renewal.
Volume: 132
Issue: 8
Pages: 791-803
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1581631 | J:512
First Author: Pritchard MA
Year: 1992
Journal: Mamm Genome
Title: Two members of the JAK family of protein tyrosine kinases map to chromosomes 1p31.3 and 9p24.
Volume: 3
Issue: 1
Pages: 36-8
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16230418 | J:102367
First Author: Nefedova Y
Year: 2005
Journal: Cancer Res
Title: Regulation of dendritic cell differentiation and antitumor immune response in cancer by pharmacologic-selective inhibition of the janus-activated kinase 2/signal transducers and activators of transcription 3 pathway.
Volume: 65
Issue: 20
Pages: 9525-35
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Publication
16254141 | J:129433
First Author: Ghaffari S
Year: 2006
Journal: Blood
Title: AKT induces erythroid-cell maturation of JAK2-deficient fetal liver progenitor cells and is required for Epo regulation of erythroid-cell differentiation.
Volume: 107
Issue: 5
Pages: 1888-91
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8272873 | J:172926
First Author: Stahl N
Year: 1994
Journal: Science
Title: Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 beta receptor components.
Volume: 263
Issue: 5143
Pages: 92-5
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Publication
25516983 | J:216926
First Author: Rampal R
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Genomic and functional analysis of leukemic transformation of myeloproliferative neoplasms.
Volume: 111
Issue: 50
Pages: E5401-10
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Publication
27222478 | J:236116
First Author: Maschalidi S
Year: 2016
Journal: Blood
Title: Therapeutic effect of JAK1/2 blockade on the manifestations of hemophagocytic lymphohistiocytosis in mice.
Volume: 128
Issue: 1
Pages: 60-71
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24608040 | J:209615
First Author: Bezbradica JS
Year: 2014
Journal: Nat Immunol
Title: A role for the ITAM signaling module in specifying cytokine-receptor functions.
Volume: 15
Issue: 4
Pages: 333-42
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Publication
17547694 | J:125734
First Author: Liu YE
Year: 2007
Journal: FEBS J
Title: Activation of Stat5 and induction of a pregnancy-like mammary gland differentiation by eicosapentaenoic and docosapentaenoic omega-3 fatty acids.
Volume: 274
Issue: 13
Pages: 3351-62
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Publication
35421216 | J:328302
First Author: Li B
Year: 2022
Journal: Blood
Title: BMP2/SMAD pathway activation in JAK2/p53-mutant megakaryocyte/erythroid progenitors promotes leukemic transformation.
Volume: 139
Issue: 25
Pages: 3630-3646
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Publication
23548897 | J:198587
First Author: Xin H
Year: 2013
Journal: J Biol Chem
Title: G-protein-coupled receptor agonist BV8/prokineticin-2 and STAT3 protein form a feed-forward loop in both normal and malignant myeloid cells.
Volume: 288
Issue: 19
Pages: 13842-9
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Publication
25217696 | J:329486
First Author: Kagoya Y
Year: 2014
Journal: Blood
Title: JAK2V617F+ myeloproliferative neoplasm clones evoke paracrine DNA damage to adjacent normal cells through secretion of lipocalin-2.
Volume: 124
Issue: 19
Pages: 2996-3006
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Publication
38729948 | J:360099
First Author: Ma JK
Year: 2024
Journal: Nat Commun
Title: TFPI from erythroblasts drives heme production in central macrophages promoting erythropoiesis in polycythemia.
Volume: 15
Issue: 1
Pages: 3976
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Publication
35598702 | J:326868
 
First Author: Zhong Y
Year: 2022
Journal: Neuroscience
Title: JAK2/STAT3 Axis Intermediates Microglia/Macrophage Polarization During Cerebral Ischemia/Reperfusion Injury.
Volume: 496
Pages: 119-128
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22999939 | J:196226
First Author: Jing X
Year: 2012
Journal: Cell Rep
Title: Crosstalk of humoral and cell-cell contact-mediated signals in postnatal body growth.
Volume: 2
Issue: 3
Pages: 652-65
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36719747 | J:355406
 
First Author: Han X
Year: 2023
Journal: J Clin Invest
Title: Targeting pleckstrin-2/Akt signaling reduces proliferation in myeloproliferative neoplasm models.
Volume: 133
Issue: 6
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22144185 | J:183821
First Author: Yan D
Year: 2012
Journal: Blood
Title: Critical requirement for Stat5 in a mouse model of polycythemia vera.
Volume: 119
Issue: 15
Pages: 3539-49
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Publication
29249691 | J:253743
First Author: Kleppe M
Year: 2018
Journal: Cancer Cell
Title: Dual Targeting of Oncogenic Activation and Inflammatory Signaling Increases Therapeutic Efficacy in Myeloproliferative Neoplasms.
Volume: 33
Issue: 1
Pages: 29-43.e7
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25552701 | J:220728
First Author: Ishikawa Y
Year: 2015
Journal: Haematologica
Title: Role of the clathrin adaptor PICALM in normal hematopoiesis and polycythemia vera pathophysiology.
Volume: 100
Issue: 4
Pages: 439-51
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28637665 | J:244956
First Author: Dutta A
Year: 2017
Journal: Blood
Title: Hmga2 promotes the development of myelofibrosis in Jak2V617F knockin mice by enhancing TGF-β1 and Cxcl12 pathways.
Volume: 130
Issue: 7
Pages: 920-932
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Publication
21264353 | J:170131
First Author: Liu Q
Year: 2011
Journal: PLoS Biol
Title: Lipoprotein receptor LRP1 regulates leptin signaling and energy homeostasis in the adult central nervous system.
Volume: 9
Issue: 1
Pages: e1000575
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33027668 | J:298886
First Author: Le BV
Year: 2020
Journal: Cell Rep
Title: TGFβR-SMAD3 Signaling Induces Resistance to PARP Inhibitors in the Bone Marrow Microenvironment.
Volume: 33
Issue: 1
Pages: 108221
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28094236 | J:274496
 
First Author: Tsunekawa T
Year: 2017
Journal: EBioMedicine
Title: Deficiency of PTP1B Attenuates Hypothalamic Inflammation via Activation of the JAK2-STAT3 Pathway in Microglia.
Volume: 16
Pages: 172-183
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9247268 | J:41857
First Author: Saiardi A
Year: 1997
Journal: Neuron
Title: Antiproliferative role of dopamine: loss of D2 receptors causes hormonal dysfunction and pituitary hyperplasia.
Volume: 19
Issue: 1
Pages: 115-26
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30592974 | J:295035
 
First Author: Mai HN
Year: 2019
Journal: Free Radic Biol Med
Title: Astrocytic mobilization of glutathione peroxidase-1 contributes to the protective potential against cocaine kindling behaviors in mice via activation of JAK2/STAT3 signaling.
Volume: 131
Pages: 408-431
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29992755 | J:289692
First Author: Yuan L
Year: 2018
Journal: J Cell Mol Med
Title: Heat-shock transcription factor 1 is critically involved in the ischaemia-induced cardiac hypertrophy via JAK2/STAT3 pathway.
Volume: 22
Issue: 9
Pages: 4292-4303
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11360203 | J:69119
First Author: Santos J
Year: 2001
Journal: Oncogene
Title: Evidence of a possible epigenetic inactivation mechanism operating on a region of mouse chromosome 19 in gamma-radiation-induced thymic lymphomas.
Volume: 20
Issue: 17
Pages: 2186-9
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38457657 | J:350973
First Author: Laranjeira ABA
Year: 2024
Journal: Blood
Title: In vivo ablation of NF-κB cascade effectors alleviates disease burden in myeloproliferative neoplasms.
Volume: 143
Issue: 23
Pages: 2414-2424
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30024857 | J:266380
First Author: Edelmann B
Year: 2018
Journal: J Clin Invest
Title: JAK2-V617F promotes venous thrombosis through β1/β2 integrin activation.
Volume: 128
Issue: 10
Pages: 4359-4371
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28278176 | J:242064
First Author: Mapes J
Year: 2017
Journal: PLoS Genet
Title: CUZD1 is a critical mediator of the JAK/STAT5 signaling pathway that controls mammary gland development during pregnancy.
Volume: 13
Issue: 3
Pages: e1006654
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18424709 | J:172969
First Author: Sebastián C
Year: 2008
Journal: J Immunol
Title: Deacetylase activity is required for STAT5-dependent GM-CSF functional activity in macrophages and differentiation to dendritic cells.
Volume: 180
Issue: 9
Pages: 5898-906
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7539296 | J:25660
First Author: Larner AC
Year: 1995
Journal: Biochim Biophys Acta
Title: Protein tyrosine phosphorylation as a mechanism which regulates cytokine activation of early response genes.
Volume: 1266
Issue: 3
Pages: 278-87
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8662243 | J:33549
First Author: Kono DH
Year: 1996
Journal: Mamm Genome
Title: Jak3 maps to chromosome 8.
Volume: 7
Issue: 6
Pages: 476-7
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10526570 | J:58302
First Author: Yeh TC
Year: 1999
Journal: Cell Mol Life Sci
Title: The Janus kinase family of protein tyrosine kinases and their role in signaling.
Volume: 55
Issue: 12
Pages: 1523-34
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15007095 | J:90486
First Author: Schmidt U
Year: 2004
Journal: J Exp Med
Title: Btk is required for an efficient response to erythropoietin and for SCF-controlled protection against TRAIL in erythroid progenitors.
Volume: 199
Issue: 6
Pages: 785-95
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14525952 | J:87740
First Author: Zabeau L
Year: 2004
Journal: Mol Endocrinol
Title: Functional analysis of leptin receptor activation using a Janus kinase/signal transducer and activator of transcription complementation assay.
Volume: 18
Issue: 1
Pages: 150-61
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Publication
17728251 | J:126848
First Author: Fujinaka Y
Year: 2007
Journal: J Biol Chem
Title: Lactogens promote beta cell survival through JAK2/STAT5 activation and Bcl-XL upregulation.
Volume: 282
Issue: 42
Pages: 30707-17
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18692472 | J:143475
First Author: Hansen G
Year: 2008
Journal: Cell
Title: The structure of the GM-CSF receptor complex reveals a distinct mode of cytokine receptor activation.
Volume: 134
Issue: 3
Pages: 496-507
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19571317 | J:152243
First Author: Wood AD
Year: 2009
Journal: Blood
Title: ID1 promotes expansion and survival of primary erythroid cells and is a target of JAK2V617F-STAT5 signaling.
Volume: 114
Issue: 9
Pages: 1820-30
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Publication
22972935 | J:187745
First Author: Doles J
Year: 2012
Journal: Genes Dev
Title: Age-associated inflammation inhibits epidermal stem cell function.
Volume: 26
Issue: 19
Pages: 2144-53
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Publication
8022486 | J:19201
First Author: Witthuhn BA
Year: 1994
Journal: Nature
Title: Involvement of the Jak-3 Janus kinase in signalling by interleukins 2 and 4 in lymphoid and myeloid cells.
Volume: 370
Issue: 6485
Pages: 153-7
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