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Search results 201 to 300 out of 329 for Keap1

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Category: Publication
Type Details Score
Publication
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication
First Author: Romero R
Year: 2020
Journal: Nat Cancer
Title: Keap1 mutation renders lung adenocarcinomas dependent on Slc33a1.
Volume: 1
Issue: 6
Pages: 589-602
Publication
First Author: Romero R
Year: 2017
Journal: Nat Med
Title: Keap1 loss promotes Kras-driven lung cancer and results in dependence on glutaminolysis.
Volume: 23
Issue: 11
Pages: 1362-1368
Publication
First Author: Tan CT
Year: 2021
Journal: EMBO Rep
Title: MOAP-1-mediated dissociation of p62/SQSTM1 bodies releases Keap1 and suppresses Nrf2 signaling.
Volume: 22
Issue: 1
Pages: e50854
Publication    
First Author: Siswanto FM
Year: 2021
Journal: J Biol Chem
Title: Sp1 is a substrate of Keap1 and regulates the activity of CRL4AWDR23 ubiquitin ligase toward Nrf2.
Pages: 100704
Publication
First Author: Lee DH
Year: 2020
Journal: Autophagy
Title: SQSTM1/p62 activates NFE2L2/NRF2 via ULK1-mediated autophagic KEAP1 degradation and protects mouse liver from lipotoxicity.
Volume: 16
Issue: 11
Pages: 1949-1973
Publication
First Author: Kim JE
Year: 2010
Journal: Cell Signal
Title: Suppression of NF-kappaB signaling by KEAP1 regulation of IKKbeta activity through autophagic degradation and inhibition of phosphorylation.
Volume: 22
Issue: 11
Pages: 1645-54
Publication
First Author: Li L
Year: 2024
Journal: Cancer Res
Title: WNK1 Interaction with KEAP1 Promotes NRF2 Stabilization to Enhance the Oxidative Stress Response in Hepatocellular Carcinoma.
Volume: 84
Issue: 17
Pages: 2776-2791
Publication
First Author: Dayalan Naidu S
Year: 2018
Journal: Sci Rep
Title: C151 in KEAP1 is the main cysteine sensor for the cyanoenone class of NRF2 activators, irrespective of molecular size or shape.
Volume: 8
Issue: 1
Pages: 8037
Publication
First Author: Adam J
Year: 2011
Journal: Cancer Cell
Title: Renal cyst formation in Fh1-deficient mice is independent of the Hif/Phd pathway: roles for fumarate in KEAP1 succination and Nrf2 signaling.
Volume: 20
Issue: 4
Pages: 524-37
Publication
First Author: Anzovino A
Year: 2017
Journal: Am J Pathol
Title: Molecular Alterations in a Mouse Cardiac Model of Friedreich Ataxia: An Impaired Nrf2 Response Mediated via Upregulation of Keap1 and Activation of the Gsk3β Axis.
Volume: 187
Issue: 12
Pages: 2858-2875
Publication
First Author: Fan W
Year: 2010
Journal: Autophagy
Title: Keap1 facilitates p62-mediated ubiquitin aggregate clearance via autophagy.
Volume: 6
Issue: 5
Pages: 614-21
Publication  
First Author: Cloer EW
Year: 2018
Journal: Mol Cell Biol
Title: p62-Dependent Phase Separation of Patient-Derived KEAP1 Mutations and NRF2.
Volume: 38
Issue: 22
Publication  
First Author: McMahon M
Year: 2018
Journal: Toxicol Appl Pharmacol
Title: Zinc-binding triggers a conformational-switch in the cullin-3 substrate adaptor protein KEAP1 that controls transcription factor NRF2.
Volume: 360
Pages: 45-57
Publication
First Author: Padmanabhan B
Year: 2008
Journal: Acta Crystallogr Sect F Struct Biol Cryst Commun
Title: Structural analysis of the complex of Keap1 with a prothymosin alpha peptide.
Volume: 64
Issue: Pt 4
Pages: 233-8
Publication
First Author: Wakabayashi N
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Protection against electrophile and oxidant stress by induction of the phase 2 response: fate of cysteines of the Keap1 sensor modified by inducers.
Volume: 101
Issue: 7
Pages: 2040-5
Publication
First Author: Strachan GD
Year: 2004
Journal: Biochemistry
Title: Fetal Alz-50 clone 1 interacts with the human orthologue of the Kelch-like Ech-associated protein.
Volume: 43
Issue: 38
Pages: 12113-22
Publication
First Author: Barak O
Year: 2003
Journal: EMBO J
Title: Isolation of human NURF: a regulator of Engrailed gene expression.
Volume: 22
Issue: 22
Pages: 6089-100
Publication
First Author: Wysocka J
Year: 2006
Journal: Nature
Title: A PHD finger of NURF couples histone H3 lysine 4 trimethylation with chromatin remodelling.
Volume: 442
Issue: 7098
Pages: 86-90
Publication
First Author: Jordan-Sciutto KL
Year: 2000
Journal: Biochemistry
Title: Fetal Alz-50 clone 1 (FAC1) protein interacts with the Myc-associated zinc finger protein (ZF87/MAZ) and alters its transcriptional activity.
Volume: 39
Issue: 12
Pages: 3206-15
Publication
First Author: Xiao H
Year: 2001
Journal: Mol Cell
Title: Dual functions of largest NURF subunit NURF301 in nucleosome sliding and transcription factor interactions.
Volume: 8
Issue: 3
Pages: 531-43
Publication
First Author: Badenhorst P
Year: 2002
Journal: Genes Dev
Title: Biological functions of the ISWI chromatin remodeling complex NURF.
Volume: 16
Issue: 24
Pages: 3186-98
Publication
First Author: Huang HC
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: Regulation of the antioxidant response element by protein kinase C-mediated phosphorylation of NF-E2-related factor 2.
Volume: 97
Issue: 23
Pages: 12475-80
Publication
First Author: Nguyen T
Year: 2004
Journal: Free Radic Biol Med
Title: The pathways and molecular mechanisms regulating Nrf2 activation in response to chemical stress.
Volume: 37
Issue: 4
Pages: 433-41
Publication
First Author: Suzuki T
Year: 2017
Journal: J Biol Chem
Title: Stress-sensing mechanisms and the physiological roles of the Keap1-Nrf2 system during cellular stress.
Volume: 292
Issue: 41
Pages: 16817-16824
Publication
First Author: Carvalho AN
Year: 2016
Journal: FEBS Lett
Title: S-Glutathionylation of Keap1: a new role for glutathione S-transferase pi in neuronal protection.
Volume: 590
Issue: 10
Pages: 1455-66
Publication
First Author: Koike S
Year: 2013
Journal: FEBS Lett
Title: Polysulfide exerts a protective effect against cytotoxicity caused by t-buthylhydroperoxide through Nrf2 signaling in neuroblastoma cells.
Volume: 587
Issue: 21
Pages: 3548-55
Publication
First Author: Sanghvi VR
Year: 2019
Journal: Cell
Title: The Oncogenic Action of NRF2 Depends on De-glycation by Fructosamine-3-Kinase.
Volume: 178
Issue: 4
Pages: 807-819.e21
Publication
First Author: Marzio A
Year: 2022
Journal: Cell
Title: EMSY inhibits homologous recombination repair and the interferon response, promoting lung cancer immune evasion.
Volume: 185
Issue: 1
Pages: 169-183.e19
Publication
First Author: Lignitto L
Year: 2019
Journal: Cell
Title: Nrf2 Activation Promotes Lung Cancer Metastasis by Inhibiting the Degradation of Bach1.
Volume: 178
Issue: 2
Pages: 316-329.e18
Publication
First Author: Gwinn DM
Year: 2018
Journal: Cancer Cell
Title: Oncogenic KRAS Regulates Amino Acid Homeostasis and Asparagine Biosynthesis via ATF4 and Alters Sensitivity to L-Asparaginase.
Volume: 33
Issue: 1
Pages: 91-107.e6
Publication
First Author: Wang P
Year: 2019
Journal: Nat Commun
Title: Macrophage achieves self-protection against oxidative stress-induced ageing through the Mst-Nrf2 axis.
Volume: 10
Issue: 1
Pages: 755
Publication
First Author: Inami Y
Year: 2011
Journal: J Cell Biol
Title: Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells.
Volume: 193
Issue: 2
Pages: 275-84
Publication
First Author: Yamada T
Year: 2018
Journal: Cell Metab
Title: Mitochondrial Stasis Reveals p62-Mediated Ubiquitination in Parkin-Independent Mitophagy and Mitigates Nonalcoholic Fatty Liver Disease.
Volume: 28
Issue: 4
Pages: 588-604.e5
Publication
First Author: Yang Y
Year: 2019
Journal: Nat Commun
Title: Cytoplasmic DAXX drives SQSTM1/p62 phase condensation to activate Nrf2-mediated stress response.
Volume: 10
Issue: 1
Pages: 3759
Publication
First Author: Toulis V
Year: 2020
Journal: Cell Rep
Title: The Deubiquitinating Enzyme Ataxin-3 Regulates Ciliogenesis and Phagocytosis in the Retina.
Volume: 33
Issue: 6
Pages: 108360
Publication
First Author: Graham DB
Year: 2018
Journal: Cell Rep
Title: Nitric Oxide Engages an Anti-inflammatory Feedback Loop Mediated by Peroxiredoxin 5 in Phagocytes.
Volume: 24
Issue: 4
Pages: 838-850
Publication
First Author: Kageyama S
Year: 2021
Journal: Nat Commun
Title: p62/SQSTM1-droplet serves as a platform for autophagosome formation and anti-oxidative stress response.
Volume: 12
Issue: 1
Pages: 16
Publication
First Author: Ding H
Year: 2021
Journal: Sci Adv
Title: Activation of the NRF2 antioxidant program sensitizes tumors to G6PD inhibition.
Volume: 7
Issue: 47
Pages: eabk1023
Publication  
First Author: Deng S
Year: 2020
Journal: Redox Biol
Title: Tsg101 positively regulates P62-Keap1-Nrf2 pathway to protect hearts against oxidative damage.
Volume: 32
Pages: 101453
Publication
First Author: Zhang XW
Year: 2022
Journal: Sci Adv
Title: Neuroinflammation inhibition by small-molecule targeting USP7 noncatalytic domain for neurodegenerative disease therapy.
Volume: 8
Issue: 32
Pages: eabo0789
Publication
First Author: Hashimoto K
Year: 2016
Journal: Antioxid Redox Signal
Title: TAK1 Regulates the Nrf2 Antioxidant System Through Modulating p62/SQSTM1.
Volume: 25
Issue: 17
Pages: 953-964
Publication
First Author: Alam MM
Year: 2017
Journal: J Biol Chem
Title: Glucocorticoid receptor signaling represses the antioxidant response by inhibiting histone acetylation mediated by the transcriptional activator NRF2.
Volume: 292
Issue: 18
Pages: 7519-7530
Publication
First Author: Ting KKY
Year: 2024
Journal: Sci Rep
Title: Cholesterol accumulation impairs HIF-1α-dependent immunometabolic reprogramming of LPS-stimulated macrophages by upregulating the NRF2 pathway.
Volume: 14
Issue: 1
Pages: 11162
Publication
First Author: Gorrini C
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Estrogen controls the survival of BRCA1-deficient cells via a PI3K-NRF2-regulated pathway.
Volume: 111
Issue: 12
Pages: 4472-7
Publication
First Author: Wang ZY
Year: 2024
Journal: Nat Commun
Title: Macrophage ILF3 promotes abdominal aortic aneurysm by inducing inflammatory imbalance in male mice.
Volume: 15
Issue: 1
Pages: 7249
Publication      
First Author: Kageyama S
Year: 2018
Journal: Mol Cell Biol
Title: Negative regulation of the Keap1-Nrf2 pathway by a p62/Sqstm1 splicing variant.
Publication  
First Author: Pennington SM
Year: 2018
Journal: Redox Biol
Title: Defective protein repair under methionine sulfoxide A deletion drives autophagy and ARE-dependent gene transcription.
Volume: 16
Pages: 401-413
Publication
First Author: Petriello MC
Year: 2014
Journal: Toxicol Appl Pharmacol
Title: PCB 126 toxicity is modulated by cross-talk between caveolae and Nrf2 signaling.
Volume: 277
Issue: 2
Pages: 192-9
Publication
First Author: Hou Y
Year: 2012
Journal: Free Radic Biol Med
Title: Nuclear factor erythroid-derived factor 2-related factor 2 regulates transcription of CCAAT/enhancer-binding protein β during adipogenesis.
Volume: 52
Issue: 2
Pages: 462-72
Publication
First Author: Kawachi Y
Year: 2008
Journal: J Invest Dermatol
Title: Attenuation of UVB-induced sunburn reaction and oxidative DNA damage with no alterations in UVB-induced skin carcinogenesis in Nrf2 gene-deficient mice.
Volume: 128
Issue: 7
Pages: 1773-9
Publication
First Author: Luo L
Year: 2015
Journal: Toxicol Appl Pharmacol
Title: Butylated hydroxyanisole induces distinct expression patterns of Nrf2 and detoxification enzymes in the liver and small intestine of C57BL/6 mice.
Volume: 288
Issue: 3
Pages: 339-48
Publication  
First Author: Qu C
Year: 2015
Journal: J Ethnopharmacol
Title: Identifying panaxynol, a natural activator of nuclear factor erythroid-2 related factor 2 (Nrf2) from American ginseng as a suppressor of inflamed macrophage-induced cardiomyocyte hypertrophy.
Volume: 168
Pages: 326-36
Publication
First Author: Wang B
Year: 2012
Journal: Free Radic Biol Med
Title: Histone deacetylase inhibition activates transcription factor Nrf2 and protects against cerebral ischemic damage.
Volume: 52
Issue: 5
Pages: 928-36
Publication
First Author: Reiss LK
Year: 2014
Journal: Am J Respir Cell Mol Biol
Title: Interplay between nuclear factor erythroid 2-related factor 2 and amphiregulin during mechanical ventilation.
Volume: 51
Issue: 5
Pages: 668-77
Publication
First Author: DeNicola GM
Year: 2011
Journal: Nature
Title: Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis.
Volume: 475
Issue: 7354
Pages: 106-9
Publication  
First Author: Liu P
Year: 2021
Journal: Mol Metab
Title: Non-canonical NRF2 activation promotes a pro-diabetic shift in hepatic glucose metabolism.
Volume: 51
Pages: 101243
Publication
First Author: Pi J
Year: 2010
Journal: J Biol Chem
Title: Deficiency in the nuclear factor E2-related factor-2 transcription factor results in impaired adipogenesis and protects against diet-induced obesity.
Volume: 285
Issue: 12
Pages: 9292-300
Publication
First Author: Singh A
Year: 2021
Journal: Clin Cancer Res
Title: NRF2 Activation Promotes Aggressive Lung Cancer and Associates with Poor Clinical Outcomes.
Volume: 27
Issue: 3
Pages: 877-888
Publication
First Author: Ikeda R
Year: 2023
Journal: EMBO J
Title: Phosphorylation of phase-separated p62 bodies by ULK1 activates a redox-independent stress response.
Volume: 42
Issue: 14
Pages: e113349
Publication
First Author: Rada P
Year: 2012
Journal: Mol Cell Biol
Title: Structural and functional characterization of Nrf2 degradation by the glycogen synthase kinase 3/β-TrCP axis.
Volume: 32
Issue: 17
Pages: 3486-99
Publication
First Author: Tapias V
Year: 2018
Journal: Hum Mol Genet
Title: Benfotiamine treatment activates the Nrf2/ARE pathway and is neuroprotective in a transgenic mouse model of tauopathy.
Volume: 27
Issue: 16
Pages: 2874-2892
Publication
First Author: Wang F
Year: 2021
Journal: Cell Mol Gastroenterol Hepatol
Title: The Ubiquitin E3 Ligase TRIM21 Promotes Hepatocarcinogenesis by Suppressing the p62-Keap1-Nrf2 Antioxidant Pathway.
Volume: 11
Issue: 5
Pages: 1369-1385
Publication
First Author: Rajasekaran NS
Year: 2011
Journal: Antioxid Redox Signal
Title: Sustained activation of nuclear erythroid 2-related factor 2/antioxidant response element signaling promotes reductive stress in the human mutant protein aggregation cardiomyopathy in mice.
Volume: 14
Issue: 6
Pages: 957-71
Publication
First Author: Kong C
Year: 2021
Journal: Cancer Res
Title: Fusobacterium Nucleatum Promotes the Development of Colorectal Cancer by Activating a Cytochrome P450/Epoxyoctadecenoic Acid Axis via TLR4/Keap1/NRF2 Signaling.
Volume: 81
Issue: 17
Pages: 4485-4498
Publication
First Author: Vomhof-DeKrey EE
Year: 2012
Journal: Free Radic Biol Med
Title: NAD(P)H:quinone oxidoreductase 1 activity reduces hypertrophy in 3T3-L1 adipocytes.
Volume: 53
Issue: 4
Pages: 690-700
Publication
First Author: Holmström KM
Year: 2013
Journal: Biol Open
Title: Nrf2 impacts cellular bioenergetics by controlling substrate availability for mitochondrial respiration.
Volume: 2
Issue: 8
Pages: 761-70
Publication
First Author: Baird L
Year: 2013
Journal: Biochem Biophys Res Commun
Title: Diffusion dynamics of the Keap1-Cullin3 interaction in single live cells.
Volume: 433
Issue: 1
Pages: 58-65
Publication  
First Author: Sachdeva MM
Year: 2014
Journal: Exp Eye Res
Title: Nrf2 signaling is impaired in the aging RPE given an oxidative insult.
Volume: 119
Pages: 111-4