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Search results 201 to 300 out of 4474 for Kl

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Categories

Category: Publication
Type Details Score
Publication
First Author: Chen J
Year: 2018
Journal: Hypertension
Title: Secreted Klotho Attenuates Inflammation-Associated Aortic Valve Fibrosis in Senescence-Accelerated Mice P1.
Volume: 71
Issue: 5
Pages: 877-885
Publication    
First Author: Clemens Z
Year: 2021
Journal: Elife
Title: The biphasic and age-dependent impact of Klotho on hallmarks of aging and skeletal muscle function.
Volume: 10
Publication
First Author: Yang YL
Year: 2020
Journal: Exp Mol Med
Title: Long noncoding RNA NEAT1 is involved in the protective effect of Klotho on renal tubular epithelial cells in diabetic kidney disease through the ERK1/2 signaling pathway.
Volume: 52
Issue: 2
Pages: 266-280
Publication
First Author: Chen Z
Year: 2020
Journal: Int J Med Sci
Title: Klotho deficiency aggravates diabetes-induced podocyte injury due to DNA damage caused by mitochondrial dysfunction.
Volume: 17
Issue: 17
Pages: 2763-2772
Publication  
First Author: Fitz NF
Year: 2023
Journal: Int J Mol Sci
Title: Extracellular Vesicles in Young Serum Contribute to the Restoration of Age-Related Brain Transcriptomes and Cognition in Old Mice.
Volume: 24
Issue: 16
Publication
First Author: Wang Q
Year: 2021
Journal: Hypertension
Title: Kidney-Specific Klotho Gene Deletion Causes Aortic Aneurysm via Hyperphosphatemia.
Volume: 78
Issue: 2
Pages: 308-319
Publication  
First Author: Kim B
Year: 2025
Journal: Biochem Biophys Res Commun
Title: α-Klotho regulates mouse embryonic neural stem cell proliferation and differentiation.
Volume: 742
Pages: 151157
Publication
First Author: Carraway KL 3rd
Year: 1997
Journal: Nature
Title: Neuregulin-2, a new ligand of ErbB3/ErbB4-receptor tyrosine kinases.
Volume: 387
Issue: 6632
Pages: 512-6
Publication
First Author: Olauson H
Year: 2012
Journal: J Am Soc Nephrol
Title: Targeted deletion of Klotho in kidney distal tubule disrupts mineral metabolism.
Volume: 23
Issue: 10
Pages: 1641-51
Publication
First Author: Dubal DB
Year: 2015
Journal: J Neurosci
Title: Life extension factor klotho prevents mortality and enhances cognition in hAPP transgenic mice.
Volume: 35
Issue: 6
Pages: 2358-71
Publication
First Author: Tomiyama K
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Relevant use of Klotho in FGF19 subfamily signaling system in vivo.
Volume: 107
Issue: 4
Pages: 1666-71
Publication
First Author: Hasegawa Y
Year: 2017
Journal: Cardiovasc Diabetol
Title: DPP-4 inhibition with linagliptin ameliorates the progression of premature aging in klotho-/- mice.
Volume: 16
Issue: 1
Pages: 154
Publication
First Author: Zhao Y
Year: 2011
Journal: Diabetes
Title: Klotho depletion contributes to increased inflammation in kidney of the db/db mouse model of diabetes via RelA (serine)536 phosphorylation.
Volume: 60
Issue: 7
Pages: 1907-16
Publication
First Author: Lin Y
Year: 2015
Journal: Diabetes
Title: In vivo pancreatic β-cell-specific expression of antiaging gene Klotho: a novel approach for preserving β-cells in type 2 diabetes.
Volume: 64
Issue: 4
Pages: 1444-58
Publication
First Author: Yu J
Year: 2010
Journal: Biochem Biophys Res Commun
Title: Decreased expression of klotho gene in uremic atherosclerosis in apolipoprotein E-deficient mice.
Volume: 391
Issue: 1
Pages: 261-6
Publication
First Author: Sastre C
Year: 2013
Journal: PLoS One
Title: Hyperlipidemia-associated renal damage decreases Klotho expression in kidneys from ApoE knockout mice.
Volume: 8
Issue: 12
Pages: e83713
Publication
First Author: Yang K
Year: 2017
Journal: Blood
Title: Indoxyl sulfate induces platelet hyperactivity and contributes to chronic kidney disease-associated thrombosis in mice.
Volume: 129
Issue: 19
Pages: 2667-2679
Publication
First Author: Takenaka T
Year: 2020
Journal: Am J Physiol Renal Physiol
Title: Klotho supplementation ameliorates blood pressure and renal function in DBA/2-pcy mice, a model of polycystic kidney disease.
Volume: 318
Issue: 3
Pages: F557-F564
Publication
First Author: Guan X
Year: 2014
Journal: J Pathol
Title: Klotho suppresses renal tubulo-interstitial fibrosis by controlling basic fibroblast growth factor-2 signalling.
Volume: 234
Issue: 4
Pages: 560-72
Publication
First Author: Kadoya H
Year: 2016
Journal: Clin Exp Nephrol
Title: Klotho attenuates renal hypertrophy and glomerular injury in Ins2Akita diabetic mice.
Volume: 20
Issue: 5
Pages: 671-678
Publication
First Author: Ohnishi M
Year: 2009
Journal: Kidney Int
Title: Reversal of mineral ion homeostasis and soft-tissue calcification of klotho knockout mice by deletion of vitamin D 1alpha-hydroxylase.
Volume: 75
Issue: 11
Pages: 1166-72
Publication
First Author: Vadakke Madathil S
Year: 2014
Journal: Am J Pathol
Title: Klotho deficiency disrupts hematopoietic stem cell development and erythropoiesis.
Volume: 184
Issue: 3
Pages: 827-41
Publication
First Author: Anour R
Year: 2012
Journal: PLoS One
Title: Klotho lacks a vitamin D independent physiological role in glucose homeostasis, bone turnover, and steady-state PTH secretion in vivo.
Volume: 7
Issue: 2
Pages: e31376
Publication
First Author: Ohnishi M
Year: 2010
Journal: FASEB J
Title: Dietary and genetic evidence for phosphate toxicity accelerating mammalian aging.
Volume: 24
Issue: 9
Pages: 3562-71
Publication
First Author: Kaludjerovic J
Year: 2017
Journal: FASEB J
Title: Klotho expression in long bones regulates FGF23 production during renal failure.
Volume: 31
Issue: 5
Pages: 2050-2064
Publication
First Author: Fan Y
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Interrelated role of Klotho and calcium-sensing receptor in parathyroid hormone synthesis and parathyroid hyperplasia.
Volume: 115
Issue: 16
Pages: E3749-E3758
Publication
First Author: Olauson H
Year: 2013
Journal: PLoS Genet
Title: Parathyroid-specific deletion of Klotho unravels a novel calcineurin-dependent FGF23 signaling pathway that regulates PTH secretion.
Volume: 9
Issue: 12
Pages: e1003975
Publication
First Author: Bai X
Year: 2009
Journal: Am J Physiol Endocrinol Metab
Title: Klotho ablation converts the biochemical and skeletal alterations in FGF23 (R176Q) transgenic mice to a Klotho-deficient phenotype.
Volume: 296
Issue: 1
Pages: E79-88
Publication
First Author: Yuan Q
Year: 2011
Journal: J Bone Miner Res
Title: FGF-23/Klotho signaling is not essential for the phosphaturic and anabolic functions of PTH.
Volume: 26
Issue: 9
Pages: 2026-35
Publication
First Author: Hu MC
Year: 2010
Journal: FASEB J
Title: Klotho: a novel phosphaturic substance acting as an autocrine enzyme in the renal proximal tubule.
Volume: 24
Issue: 9
Pages: 3438-50
Publication
First Author: Nakatani T
Year: 2009
Journal: FASEB J
Title: In vivo genetic evidence for klotho-dependent, fibroblast growth factor 23 (Fgf23) -mediated regulation of systemic phosphate homeostasis.
Volume: 23
Issue: 2
Pages: 433-41
Publication
First Author: Bøllehuus Hansen L
Year: 2020
Journal: FASEB J
Title: Influence of FGF23 and Klotho on male reproduction: Systemic vs direct effects.
Volume: 34
Issue: 9
Pages: 12436-12449
Publication
First Author: Wirrig EE
Year: 2015
Journal: Arterioscler Thromb Vasc Biol
Title: COX2 inhibition reduces aortic valve calcification in vivo.
Volume: 35
Issue: 4
Pages: 938-47
Publication
First Author: Pai HL
Year: 2023
Journal: Am J Pathol
Title: Klotho Null Mutation Involvement in Adenosine A2B Receptor-Related Skeletal Muscle Degeneration.
Volume: 193
Issue: 7
Pages: 950-959
Publication
First Author: Agarwal I
Year: 2014
Journal: J Am Heart Assoc
Title: Fibroblast growth factor-23 and cardiac structure and function.
Volume: 3
Issue: 1
Pages: e000584
Publication
First Author: Rutkowski JM
Year: 2017
Journal: Kidney Int
Title: Adiponectin alters renal calcium and phosphate excretion through regulation of klotho expression.
Volume: 91
Issue: 2
Pages: 324-337
Publication  
First Author: Daryadel A
Year: 2024
Journal: Endocrinology
Title: Zona Glomerulosa-Derived Klotho Modulates Aldosterone Synthase Expression in Young Female Mice.
Volume: 165
Issue: 5
Publication
First Author: Liu Y
Year: 2019
Journal: Mol Ther
Title: MicroRNA-34a Promotes Renal Fibrosis by Downregulation of Klotho in Tubular Epithelial Cells.
Volume: 27
Issue: 5
Pages: 1051-1065
Publication
First Author: Nagasu H
Year: 2011
Journal: Biochem Biophys Res Commun
Title: Overexpression of klotho protein modulates uninephrectomy-induced compensatory renal hypertrophy by suppressing IGF-I signals.
Volume: 407
Issue: 1
Pages: 39-43
Publication
First Author: McKee CM
Year: 2022
Journal: FASEB J
Title: The anti-aging protein Klotho affects early postnatal myogenesis by downregulating Jmjd3 and the canonical Wnt pathway.
Volume: 36
Issue: 3
Pages: e22192
Publication
First Author: Doi S
Year: 2011
Journal: J Biol Chem
Title: Klotho inhibits transforming growth factor-beta1 (TGF-beta1) signaling and suppresses renal fibrosis and cancer metastasis in mice.
Volume: 286
Issue: 10
Pages: 8655-65
Publication
First Author: Li Y
Year: 2013
Journal: Calcif Tissue Int
Title: FGF23 affects the lineage fate determination of mesenchymal stem cells.
Volume: 93
Issue: 6
Pages: 556-64
Publication
First Author: Boisvert NC
Year: 2018
Journal: Am J Physiol Renal Physiol
Title: Ubiquitin COOH-terminal hydrolase L1 deletion is associated with urinary α-klotho deficiency and perturbed phosphate homeostasis.
Volume: 315
Issue: 2
Pages: F353-F363
Publication
First Author: Ho WY
Year: 2020
Journal: Acta Neuropathol Commun
Title: Deregulated expression of a longevity gene, Klotho, in the C9orf72 deletion mice with impaired synaptic plasticity and adult hippocampal neurogenesis.
Volume: 8
Issue: 1
Pages: 155
Publication
First Author: Jankowski J
Year: 2024
Journal: Commun Biol
Title: Sexually dimorphic renal expression of mouse Klotho is directed by a kidney-specific distal enhancer responsive to HNF1b.
Volume: 7
Issue: 1
Pages: 1142
Publication
First Author: Johnson FB
Year: 1999
Journal: Cell
Title: Molecular biology of aging.
Volume: 96
Issue: 2
Pages: 291-302
Publication
First Author: Chang Q
Year: 2005
Journal: Science
Title: The beta-glucuronidase klotho hydrolyzes and activates the TRPV5 channel.
Volume: 310
Issue: 5747
Pages: 490-3
Publication
First Author: Cha SK
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Removal of sialic acid involving Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1.
Volume: 105
Issue: 28
Pages: 9805-10
Publication
First Author: Kuang X
Year: 2014
Journal: Neurobiol Aging
Title: Klotho upregulation contributes to the neuroprotection of ligustilide in an Alzheimer's disease mouse model.
Volume: 35
Issue: 1
Pages: 169-78
Publication
First Author: Gao Q
Year: 2022
Journal: Aging Cell
Title: Inhibition of DNA methyltransferase aberrations reinstates antioxidant aging suppressors and ameliorates renal aging.
Volume: 21
Issue: 1
Pages: e13526
Publication
First Author: Fang Y
Year: 2014
Journal: Kidney Int
Title: Early chronic kidney disease-mineral bone disorder stimulates vascular calcification.
Volume: 85
Issue: 1
Pages: 142-50
Publication
First Author: Kawai M
Year: 2013
Journal: J Biol Chem
Title: FGF23 suppresses chondrocyte proliferation in the presence of soluble α-Klotho both in vitro and in vivo.
Volume: 288
Issue: 4
Pages: 2414-27
Publication
First Author: Nakatani T
Year: 2009
Journal: FASEB J
Title: Inactivation of klotho function induces hyperphosphatemia even in presence of high serum fibroblast growth factor 23 levels in a genetically engineered hypophosphatemic (Hyp) mouse model.
Volume: 23
Issue: 11
Pages: 3702-11
Publication
First Author: Gomez-Stallons MV
Year: 2016
Journal: Arterioscler Thromb Vasc Biol
Title: Bone Morphogenetic Protein Signaling Is Required for Aortic Valve Calcification.
Volume: 36
Issue: 7
Pages: 1398-405
Publication
First Author: Lindberg K
Year: 2013
Journal: PLoS One
Title: Arterial klotho expression and FGF23 effects on vascular calcification and function.
Volume: 8
Issue: 4
Pages: e60658
Publication
First Author: Medici D
Year: 2008
Journal: J Cell Biol
Title: FGF-23-Klotho signaling stimulates proliferation and prevents vitamin D-induced apoptosis.
Volume: 182
Issue: 3
Pages: 459-65
Publication
First Author: Murali SK
Year: 2016
Journal: J Bone Miner Res
Title: FGF23 Regulates Bone Mineralization in a 1,25(OH)2 D3 and Klotho-Independent Manner.
Volume: 31
Issue: 1
Pages: 129-42
Publication
First Author: Andrukhova O
Year: 2017
Journal: J Bone Miner Res
Title: Klotho Lacks an FGF23-Independent Role in Mineral Homeostasis.
Volume: 32
Issue: 10
Pages: 2049-2061
Publication
First Author: Slavic S
Year: 2017
Journal: Sci Rep
Title: Genetic Ablation of Fgf23 or Klotho Does not Modulate Experimental Heart Hypertrophy Induced by Pressure Overload.
Volume: 7
Issue: 1
Pages: 11298
Publication
First Author: Hanazaki A
Year: 2020
Journal: Physiol Rep
Title: Role of sodium-dependent Pi transporter/Npt2c on Pi homeostasis in klotho knockout mice different properties between juvenile and adult stages.
Volume: 8
Issue: 3
Pages: e14324
Publication
First Author: Christov M
Year: 2011
Journal: Endocrinology
Title: Genetic ablation of sfrp4 in mice does not affect serum phosphate homeostasis.
Volume: 152
Issue: 5
Pages: 2031-6
Publication
First Author: Ide N
Year: 2016
Journal: Kidney Int
Title: In vivo evidence for a limited role of proximal tubular Klotho in renal phosphate handling.
Volume: 90
Issue: 2
Pages: 348-362
Publication
First Author: Wu YL
Year: 2017
Journal: Kidney Int
Title: Inhibition of TRPC6 channels ameliorates renal fibrosis and contributes to renal protection by soluble klotho.
Volume: 91
Issue: 4
Pages: 830-841
Publication
First Author: Landry T
Year: 2020
Journal: Diabetes
Title: Central α-Klotho Suppresses NPY/AgRP Neuron Activity and Regulates Metabolism in Mice.
Volume: 69
Issue: 7
Pages: 1368-1381
Publication
First Author: Du C
Year: 2022
Journal: Cell Rep
Title: Renal Klotho and inorganic phosphate are extrinsic factors that antagonistically regulate hematopoietic stem cell maintenance.
Volume: 38
Issue: 7
Pages: 110392
Publication
First Author: Li P
Year: 2020
Journal: Am J Physiol Renal Physiol
Title: Beclin 1/Bcl-2 complex-dependent autophagy activity modulates renal susceptibility to ischemia-reperfusion injury and mediates renoprotection by Klotho.
Volume: 318
Issue: 3
Pages: F772-F792
Publication
First Author: Gu Y
Year: 2019
Journal: Aging (Albany NY)
Title: Loss of Klotho contributes to cartilage damage by derepression of canonical Wnt/β-catenin signaling in osteoarthritis mice.
Volume: 11
Issue: 24
Pages: 12793-12809
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication
First Author: Xiao L
Year: 2010
Journal: J Biol Chem
Title: Nuclear isoforms of fibroblast growth factor 2 are novel inducers of hypophosphatemia via modulation of FGF23 and KLOTHO.
Volume: 285
Issue: 4
Pages: 2834-46
Publication
First Author: Andrukhova O
Year: 2014
Journal: EMBO Mol Med
Title: FGF23 regulates renal sodium handling and blood pressure.
Volume: 6
Issue: 6
Pages: 744-59
Publication
First Author: Delitsikou V
Year: 2020
Journal: FASEB J
Title: Klotho regulation by albuminuria is dependent on ATF3 and endoplasmic reticulum stress.
Volume: 34
Issue: 2
Pages: 2087-2104
Publication
First Author: Li H
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Soluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APP.
Volume: 107
Issue: 40
Pages: 17362-7
Publication  
First Author: Han X
Year: 2020
Journal: J Mol Cell Cardiol
Title: FGF23 induced left ventricular hypertrophy mediated by FGFR4 signaling in the myocardium is attenuated by soluble Klotho in mice.
Volume: 138
Pages: 66-74
Publication  
First Author: Andrukhova O
Year: 2016
Journal: Mol Cell Endocrinol
Title: Fgf23 and parathyroid hormone signaling interact in kidney and bone.
Volume: 436
Pages: 224-39
Publication
First Author: Yuan Q
Year: 2012
Journal: PLoS Genet
Title: Deletion of PTH rescues skeletal abnormalities and high osteopontin levels in Klotho-/- mice.
Volume: 8
Issue: 5
Pages: e1002726
Publication
First Author: Kurosu H
Year: 2009
Journal: Mol Cell Endocrinol
Title: The Klotho gene family as a regulator of endocrine fibroblast growth factors.
Volume: 299
Issue: 1
Pages: 72-8
Publication
First Author: Bloch L
Year: 2009
Journal: FEBS Lett
Title: Klotho is a substrate for alpha-, beta- and gamma-secretase.
Volume: 583
Issue: 19
Pages: 3221-4
Publication
First Author: Liu S
Year: 2008
Journal: J Am Soc Nephrol
Title: FGFR3 and FGFR4 do not mediate renal effects of FGF23.
Volume: 19
Issue: 12
Pages: 2342-50
Publication
First Author: Goetz R
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Isolated C-terminal tail of FGF23 alleviates hypophosphatemia by inhibiting FGF23-FGFR-Klotho complex formation.
Volume: 107
Issue: 1
Pages: 407-12
Publication
First Author: Takeshita A
Year: 2018
Journal: Sci Rep
Title: Central role of the proximal tubular αKlotho/FGF receptor complex in FGF23-regulated phosphate and vitamin D metabolism.
Volume: 8
Issue: 1
Pages: 6917
Publication  
First Author: Kawakami K
Year: 2017
Journal: Sci Rep
Title: Persistent fibroblast growth factor 23 signalling in the parathyroid glands for secondary hyperparathyroidism in mice with chronic kidney disease.
Volume: 7
Pages: 40534
Publication
First Author: Ide N
Year: 2018
Journal: Am J Physiol Renal Physiol
Title: In vivo evidence for an interplay of FGF23/Klotho/PTH axis on the phosphate handling in renal proximal tubules.
Volume: 315
Issue: 5
Pages: F1261-F1270
Publication
First Author: Andrukhova O
Year: 2014
Journal: EMBO J
Title: FGF23 promotes renal calcium reabsorption through the TRPV5 channel.
Volume: 33
Issue: 3
Pages: 229-46
Publication
First Author: Kurosu H
Year: 2006
Journal: J Biol Chem
Title: Regulation of fibroblast growth factor-23 signaling by klotho.
Volume: 281
Issue: 10
Pages: 6120-3
Publication
First Author: Sakurai A
Year: 2017
Journal: Biomed Res
Title: Chronological immunolocalization of sclerostin and FGF23 in the mouse metaphyseal trabecular and cortical bone.
Volume: 38
Issue: 4
Pages: 257-267
Publication
First Author: Ohata Y
Year: 2014
Journal: J Bone Miner Res
Title: Elevated fibroblast growth factor 23 exerts its effects on placenta and regulates vitamin D metabolism in pregnancy of Hyp mice.
Volume: 29
Issue: 7
Pages: 1627-38
Publication
First Author: Ratzka A
Year: 2011
Journal: PLoS One
Title: FGF-2 deficiency does not influence FGF ligand and receptor expression during development of the nigrostriatal system.
Volume: 6
Issue: 8
Pages: e23564
Publication
First Author: Rios JJ
Year: 2021
Journal: J Bone Miner Res
Title: Germline Saturation Mutagenesis Induces Skeletal Phenotypes in Mice.
Volume: 36
Issue: 8
Pages: 1548-1565
Publication  
First Author: Pérez-Estrada JR
Year: 2019
Journal: Free Radic Biol Med
Title: Reduced lifespan of mice lacking catalase correlates with altered lipid metabolism without oxidative damage or premature aging.
Volume: 135
Pages: 102-115
Publication      
First Author: The Australian Phenomics Facility at The Australian National University
Year: 2006
Journal: MGI Direct Data Submission
Title: Heritable mouse mutants from the ENU mutagenesis program at the Australian Phenomics Facility at The Australian National University
Publication      
First Author: Lexicon Genetics Inc
Year: 2005
Journal: MGI Direct Data Submission
Title: NIH initiative supporting placement of Lexicon Genetics, Inc. mice into public repositories
Publication
First Author: Quina LA
Year: 2009
Journal: J Neurosci
Title: Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development.
Volume: 29
Issue: 45
Pages: 14309-22
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication      
First Author: The Jackson Laboratory
Year: 2005
Journal: Unpublished
Title: Information obtained from The Jackson Laboratory, Bar Harbor, ME
Publication        
First Author: GO Central curators, GOA curators, Rhea curators
Year: 2020
Title: Automatic Gene Ontology annotation based on Rhea mapping
Publication        
First Author: GOA curators, MGI curators
Year: 2001
Title: Gene Ontology annotation based on Enzyme Commission mapping
Publication      
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)