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Search results 201 to 300 out of 801 for Lgr5

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Category: Publication
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Type Details Score
Publication
22388892 | J:196030
First Author: Wong VW
Year: 2012
Journal: Nat Cell Biol
Title: Lrig1 controls intestinal stem-cell homeostasis by negative regulation of ErbB signalling.
Volume: 14
Issue: 4
Pages: 401-8
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Publication
31980634 | J:284273
First Author: Abo H
Year: 2020
Journal: Nat Commun
Title: Erythroid differentiation regulator-1 induced by microbiota in early life drives intestinal stem cell proliferation and regeneration.
Volume: 11
Issue: 1
Pages: 513
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Publication
31930988 | J:292470
First Author: Gao Y
Year: 2020
Journal: Gastroenterology
Title: LKB1 Represses ATOH1 via PDK4 and Energy Metabolism and Regulates Intestinal Stem Cell Fate.
Volume: 158
Issue: 5
Pages: 1389-1401.e10
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Publication
24882705 | J:328962
First Author: Nigro G
Year: 2014
Journal: Cell Host Microbe
Title: The cytosolic bacterial peptidoglycan sensor Nod2 affords stem cell protection and links microbes to gut epithelial regeneration.
Volume: 15
Issue: 6
Pages: 792-8
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Publication
32025032 | J:292580
First Author: Tan SH
Year: 2020
Journal: Nature
Title: AQP5 enriches for stem cells and cancer origins in the distal stomach.
Volume: 578
Issue: 7795
Pages: 437-443
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Publication
31207192 | J:289334
First Author: Liu Z
Year: 2019
Journal: FASEB J
Title: β-Arrestin1-mediated decrease in endoplasmic reticulum stress impairs intestinal stem cell proliferation following radiation.
Volume: 33
Issue: 9
Pages: 10165-10176
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Publication
27573849 | J:235576
First Author: Sasaki N
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Reg4+ deep crypt secretory cells function as epithelial niche for Lgr5+ stem cells in colon.
Volume: 113
Issue: 37
Pages: E5399-407
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Publication
30996297 | J:279914
First Author: Kim Y
Year: 2019
Journal: Sci Rep
Title: Loss of PKM2 in Lgr5+ intestinal stem cells promotes colitis-associated colorectal cancer.
Volume: 9
Issue: 1
Pages: 6212
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Publication
22304925 | J:181333
First Author: Itzkovitz S
Year: 2012
Journal: Cell
Title: Optimality in the development of intestinal crypts.
Volume: 148
Issue: 3
Pages: 608-19
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Publication
30157426 | J:271549
First Author: Schmitt M
Year: 2018
Journal: Cell Rep
Title: Paneth Cells Respond to Inflammation and Contribute to Tissue Regeneration by Acquiring Stem-like Features through SCF/c-Kit Signaling.
Volume: 24
Issue: 9
Pages: 2312-2328.e7
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Publication
22821983 | J:323380
First Author: Doupé DP
Year: 2012
Journal: Science
Title: A single progenitor population switches behavior to maintain and repair esophageal epithelium.
Volume: 337
Issue: 6098
Pages: 1091-3
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Publication
29760650 | J:310834
 
First Author: You D
Year: 2018
Journal: Front Mol Neurosci
Title: Characterization of Wnt and Notch-Responsive Lgr5+ Hair Cell Progenitors in the Striolar Region of the Neonatal Mouse Utricle.
Volume: 11
Pages: 137
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Publication
28943029 | J:355266
First Author: Miura S
Year: 2017
Journal: Cell Stem Cell
Title: Generation of Mouse and Human Organoid-Forming Intestinal Progenitor Cells by Direct Lineage Reprogramming.
Volume: 21
Issue: 4
Pages: 456-471.e5
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Publication
29664186 | J:268206
First Author: Dai Q
Year: 2018
Journal: Stem Cells
Title: Notch Signaling Regulates Lgr5+ Olfactory Epithelium Progenitor/Stem Cell Turnover and Mediates Recovery of Lesioned Olfactory Epithelium in Mouse Model.
Volume: 36
Issue: 8
Pages: 1259-1272
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Publication
22945646 | J:199981
First Author: da Silva-Diz V
Year: 2013
Journal: Oncogene
Title: Progeny of Lgr5-expressing hair follicle stem cell contributes to papillomavirus-induced tumor development in epidermis.
Volume: 32
Issue: 32
Pages: 3732-43
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Publication
25664616 | J:255102
First Author: Gracz AD
Year: 2015
Journal: Nat Cell Biol
Title: A high-throughput platform for stem cell niche co-cultures and downstream gene expression analysis.
Volume: 17
Issue: 3
Pages: 340-9
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Publication
28228258 | J:251064
First Author: McLean WJ
Year: 2017
Journal: Cell Rep
Title: Clonal Expansion of Lgr5-Positive Cells from Mammalian Cochlea and High-Purity Generation of Sensory Hair Cells.
Volume: 18
Issue: 8
Pages: 1917-1929
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Publication
38201250 | J:352222
 
First Author: Zitter RC
Year: 2023
Journal: Cells
Title: LGR5+ Intestinal Stem Cells Display Sex-Dependent Radiosensitivity.
Volume: 13
Issue: 1
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Publication
30270040 | J:267381
First Author: Moor AE
Year: 2018
Journal: Cell
Title: Spatial Reconstruction of Single Enterocytes Uncovers Broad Zonation along the Intestinal Villus Axis.
Volume: 175
Issue: 4
Pages: 1156-1167.e15
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Publication
24209744 | J:205131
First Author: Leushacke M
Year: 2013
Journal: Cell Rep
Title: Lgr5(+) gastric stem cells divide symmetrically to effect epithelial homeostasis in the pylorus.
Volume: 5
Issue: 2
Pages: 349-56
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Publication
25109331 | J:222531
First Author: Riemer P
Year: 2015
Journal: Oncogene
Title: Transgenic expression of oncogenic BRAF induces loss of stem cells in the mouse intestine, which is antagonized by β-catenin activity.
Volume: 34
Issue: 24
Pages: 3164-75
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Publication
20978345 | J:166917
First Author: Bongers G
Year: 2010
Journal: J Clin Invest
Title: The cytomegalovirus-encoded chemokine receptor US28 promotes intestinal neoplasia in transgenic mice.
Volume: 120
Issue: 11
Pages: 3969-78
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Publication
31427926 | J:310544
 
First Author: Zhang S
Year: 2019
Journal: Front Mol Neurosci
Title: Frizzled-9+ Supporting Cells Are Progenitors for the Generation of Hair Cells in the Postnatal Mouse Cochlea.
Volume: 12
Pages: 184
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Publication
31092921 | J:283354
First Author: Guiu J
Year: 2019
Journal: Nature
Title: Tracing the origin of adult intestinal stem cells.
Volume: 570
Issue: 7759
Pages: 107-111
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28813421 | J:253067
First Author: Sigal M
Year: 2017
Journal: Nature
Title: Stromal R-spondin orchestrates gastric epithelial stem cells and gland homeostasis.
Volume: 548
Issue: 7668
Pages: 451-455
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Publication
36276637 | J:330592
First Author: Yang X
Year: 2022
Journal: Theranostics
Title: Identifying the E2F3-MEX3A-KLF4 signaling axis that sustains cancer cells in undifferentiated and proliferative state.
Volume: 12
Issue: 16
Pages: 6865-6882
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Publication
37967175 | J:358221
First Author: He J
Year: 2023
Journal: Sci Adv
Title: Inactivation of the tumor suppressor gene Apc synergizes with H. pylori to induce DNA damage in murine gastric stem and progenitor cells.
Volume: 9
Issue: 46
Pages: eadh0322
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Publication
24045232 | J:202471
First Author: Huch M
Year: 2013
Journal: EMBO J
Title: Unlimited in vitro expansion of adult bi-potent pancreas progenitors through the Lgr5/R-spondin axis.
Volume: 32
Issue: 20
Pages: 2708-21
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Publication
35130302 | J:322522
First Author: Alaqbi SS
Year: 2022
Journal: PLoS One
Title: Increased mitochondrial proline metabolism sustains proliferation and survival of colorectal cancer cells.
Volume: 17
Issue: 2
Pages: e0262364
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Publication
25013930 | J:219037
First Author: Lo Sasso G
Year: 2014
Journal: PLoS One
Title: Loss of Sirt1 function improves intestinal anti-bacterial defense and protects from colitis-induced colorectal cancer.
Volume: 9
Issue: 7
Pages: e102495
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Publication
31598881 | J:290826
First Author: Jiang H
Year: 2019
Journal: Front Med
Title: Unidirectional and stage-dependent roles of Notch1 in Wnt-responsive Lgr5+ cells during mouse inner ear development.
Volume: 13
Issue: 6
Pages: 705-712
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Publication
28452345 | J:251730
 
First Author: Xian L
Year: 2017
Journal: Nat Commun
Title: HMGA1 amplifies Wnt signalling and expands the intestinal stem cell compartment and Paneth cell niche.
Volume: 8
Pages: 15008
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Publication
35738677 | J:332084
First Author: Singh PNP
Year: 2022
Journal: Genes Dev
Title: Cell and chromatin transitions in intestinal stem cell regeneration.
Volume: 36
Issue: 11-12
Pages: 684-698
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Publication
29051494 | J:271420
First Author: Lv C
Year: 2017
Journal: Nat Commun
Title: MiR-31 promotes mammary stem cell expansion and breast tumorigenesis by suppressing Wnt signaling antagonists.
Volume: 8
Issue: 1
Pages: 1036
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36631663 | J:332604
   
First Author: Adpaikar AA
Year: 2023
Journal: Exp Mol Med
Title: Epithelial plasticity enhances regeneration of committed taste receptor cells following nerve injury.
Pages: 1-12
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31659152 | J:285557
First Author: Burocziova M
Year: 2019
Journal: Cell Death Dis
Title: Truncated PPM1D impairs stem cell response to genotoxic stress and promotes growth of APC-deficient tumors in the mouse colon.
Volume: 10
Issue: 11
Pages: 818
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33470182 | J:306538
First Author: Ichinose M
Year: 2021
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Stromal DLK1 promotes proliferation and inhibits differentiation of the intestinal epithelium during development.
Volume: 320
Issue: 4
Pages: G506-G520
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22848656 | J:189691
First Author: Nagel JM
Year: 2012
Journal: PLoS One
Title: Reduced intestinal tumorigenesis in APCmin mice lacking melanin-concentrating hormone.
Volume: 7
Issue: 7
Pages: e41914
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32958778 | J:303348
First Author: Chakravarti D
Year: 2020
Journal: Nat Commun
Title: Telomere dysfunction activates YAP1 to drive tissue inflammation.
Volume: 11
Issue: 1
Pages: 4766
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26644583 | J:228306
First Author: Tinkum KL
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Fasting protects mice from lethal DNA damage by promoting small intestinal epithelial stem cell survival.
Volume: 112
Issue: 51
Pages: E7148-54
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27736879 | J:236234
First Author: Ohashi W
Year: 2016
Journal: PLoS Genet
Title: Zinc Transporter SLC39A7/ZIP7 Promotes Intestinal Epithelial Self-Renewal by Resolving ER Stress.
Volume: 12
Issue: 10
Pages: e1006349
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Publication
35333576 | J:324315
First Author: Zhang T
Year: 2022
Journal: Sci Adv
Title: m6A mRNA modification maintains colonic epithelial cell homeostasis via NF-κB-mediated antiapoptotic pathway.
Volume: 8
Issue: 12
Pages: eabl5723
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26489894 | J:275048
First Author: San Roman AK
Year: 2015
Journal: Stem Cell Reports
Title: Distinct Processes and Transcriptional Targets Underlie CDX2 Requirements in Intestinal Stem Cells and Differentiated Villus Cells.
Volume: 5
Issue: 5
Pages: 673-681
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Publication
31260439 | J:277196
First Author: Wang T
Year: 2019
Journal: PLoS Biol
Title: Uncoordinated maturation of developing and regenerating postnatal mammalian vestibular hair cells.
Volume: 17
Issue: 7
Pages: e3000326
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Publication
34582804 | J:321745
First Author: Gu W
Year: 2022
Journal: Cell Stem Cell
Title: SATB2 preserves colon stem cell identity and mediates ileum-colon conversion via enhancer remodeling.
Volume: 29
Issue: 1
Pages: 101-115.e10
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Publication
30905509 | J:274684
First Author: Jadhav U
Year: 2019
Journal: Mol Cell
Title: Extensive Recovery of Embryonic Enhancer and Gene Memory Stored in Hypomethylated Enhancer DNA.
Volume: 74
Issue: 3
Pages: 542-554.e5
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34818540 | J:334271
First Author: Terranova CJ
Year: 2021
Journal: Cell Rep
Title: Reprogramming of H3K9bhb at regulatory elements is a key feature of fasting in the small intestine.
Volume: 37
Issue: 8
Pages: 110044
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23816884 | J:204752
First Author: Pitzonka L
Year: 2013
Journal: Mol Cell Biol
Title: The THO ribonucleoprotein complex is required for stem cell homeostasis in the adult mouse small intestine.
Volume: 33
Issue: 17
Pages: 3505-14
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Publication
25092767 | J:216072
First Author: Basak O
Year: 2014
Journal: EMBO J
Title: Mapping early fate determination in Lgr5+ crypt stem cells using a novel Ki67-RFP allele.
Volume: 33
Issue: 18
Pages: 2057-68
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28812582 | J:250143
First Author: Schell JC
Year: 2017
Journal: Nat Cell Biol
Title: Control of intestinal stem cell function and proliferation by mitochondrial pyruvate metabolism.
Volume: 19
Issue: 9
Pages: 1027-1036
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Publication
31778829 | J:330774
First Author: Kim CK
Year: 2020
Journal: Cell Mol Gastroenterol Hepatol
Title: Krüppel-like Factor 5 Regulates Stemness, Lineage Specification, and Regeneration of Intestinal Epithelial Stem Cells.
Volume: 9
Issue: 4
Pages: 587-609
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Publication
36584686 | J:332910
First Author: Xia M
Year: 2023
Journal: Stem Cell Reports
Title: Generation of innervated cochlear organoid recapitulates early development of auditory unit.
Volume: 18
Issue: 1
Pages: 319-336
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26939755 | J:231673
First Author: Gustin SE
Year: 2016
Journal: Dev Biol
Title: WNT/β-catenin and p27/FOXL2 differentially regulate supporting cell proliferation in the developing ovary.
Volume: 412
Issue: 2
Pages: 250-60
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21519145 | J:173930
First Author: Grachtchouk M
Year: 2011
Journal: J Clin Invest
Title: Basal cell carcinomas in mice arise from hair follicle stem cells and multiple epithelial progenitor populations.
Volume: 121
Issue: 5
Pages: 1768-81
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27867006 | J:252213
First Author: Matsu-Ura T
Year: 2016
Journal: Mol Cell
Title: Intercellular Coupling of the Cell Cycle and Circadian Clock in Adult Stem Cell Culture.
Volume: 64
Issue: 5
Pages: 900-912
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19806668 | J:155223
First Author: Suomalainen M
Year: 2010
Journal: Dev Dyn
Title: Patterns of Wnt pathway activity in the mouse incisor indicate absence of Wnt/beta-catenin signaling in the epithelial stem cells.
Volume: 239
Issue: 1
Pages: 364-72
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34496236 | J:320670
First Author: He X
Year: 2021
Journal: Cell Rep
Title: Tumor-initiating stem cell shapes its microenvironment into an immunosuppressive barrier and pro-tumorigenic niche.
Volume: 36
Issue: 10
Pages: 109674
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25655195 | J:221970
First Author: Witkowski MT
Year: 2015
Journal: Leukemia
Title: Activated Notch counteracts Ikaros tumor suppression in mouse and human T-cell acute lymphoblastic leukemia.
Volume: 29
Issue: 6
Pages: 1301-11
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25834110 | J:234079
First Author: Kundu P
Year: 2015
Journal: Sci Transl Med
Title: An EphB-Abl signaling pathway is associated with intestinal tumor initiation and growth.
Volume: 7
Issue: 281
Pages: 281ra44
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30794774 | J:286176
First Author: Fu T
Year: 2019
Journal: Cell
Title: FXR Regulates Intestinal Cancer Stem Cell Proliferation.
Volume: 176
Issue: 5
Pages: 1098-1112.e18
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21041628 | J:166608
First Author: Qiu W
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Chemoprevention by nonsteroidal anti-inflammatory drugs eliminates oncogenic intestinal stem cells via SMAC-dependent apoptosis.
Volume: 107
Issue: 46
Pages: 20027-32
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26849305 | J:296290
First Author: Bu P
Year: 2016
Journal: Cell Stem Cell
Title: A miR-34a-Numb Feedforward Loop Triggered by Inflammation Regulates Asymmetric Stem Cell Division in Intestine and Colon Cancer.
Volume: 18
Issue: 2
Pages: 189-202
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24626089 | J:211557
First Author: Nakaya T
Year: 2014
Journal: Cancer Res
Title: KLF5 regulates the integrity and oncogenicity of intestinal stem cells.
Volume: 74
Issue: 10
Pages: 2882-91
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26168291 | J:228762
First Author: Nassar D
Year: 2015
Journal: Nat Med
Title: Genomic landscape of carcinogen-induced and genetically induced mouse skin squamous cell carcinoma.
Volume: 21
Issue: 8
Pages: 946-54
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33826887 | J:317399
First Author: van der Post S
Year: 2021
Journal: Cell Rep
Title: NOX1-dependent redox signaling potentiates colonic stem cell proliferation to adapt to the intestinal microbiota by linking EGFR and TLR activation.
Volume: 35
Issue: 1
Pages: 108949
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26541605 | J:299365
First Author: Yun J
Year: 2015
Journal: Science
Title: Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH.
Volume: 350
Issue: 6266
Pages: 1391-6
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37777550 | J:357229
First Author: Omrani O
Year: 2023
Journal: Nat Commun
Title: IFNγ-Stat1 axis drives aging-associated loss of intestinal tissue homeostasis and regeneration.
Volume: 14
Issue: 1
Pages: 6109
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25620640 | J:224020
First Author: Schuijers J
Year: 2015
Journal: Cell Stem Cell
Title: Ascl2 acts as an R-spondin/Wnt-responsive switch to control stemness in intestinal crypts.
Volume: 16
Issue: 2
Pages: 158-70
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22895187 | J:186765
First Author: Koo BK
Year: 2012
Journal: Nature
Title: Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors.
Volume: 488
Issue: 7413
Pages: 665-9
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36546734 | J:335576
First Author: Sasatani M
Year: 2023
Journal: Carcinogenesis
Title: Morphology dynamics in intestinal crypt during postnatal development affect age-dependent susceptibility to radiation-induced intestinal tumorigenesis in ApcMin/+ mice: possible mechanisms of radiation tumorigenesis.
Volume: 44
Issue: 1
Pages: 105-118
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37468468 | J:338209
First Author: Erazo-Oliveras A
Year: 2023
Journal: Nat Commun
Title: Mutant APC reshapes Wnt signaling plasma membrane nanodomains by altering cholesterol levels via oncogenic β-catenin.
Volume: 14
Issue: 1
Pages: 4342
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39320349 | J:355476
   
First Author: Hua X
Year: 2024
Journal: Elife
Title: A Ctnnb1 enhancer transcriptionally regulates Wnt signaling dosage to balance homeostasis and tumorigenesis of intestinal epithelia.
Volume: 13
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22264787 | J:180282
First Author: Quante M
Year: 2012
Journal: Cancer Cell
Title: Bile acid and inflammation activate gastric cardia stem cells in a mouse model of Barrett-like metaplasia.
Volume: 21
Issue: 1
Pages: 36-51
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37172822 | J:359524
First Author: Burr AHP
Year: 2023
Journal: Cell Mol Gastroenterol Hepatol
Title: Excess Dietary Sugar Alters Colonocyte Metabolism and Impairs the Proliferative Response to Damage.
Volume: 16
Issue: 2
Pages: 287-316
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30119997 | J:277045
First Author: Metidji A
Year: 2018
Journal: Immunity
Title: The Environmental Sensor AHR Protects from Inflammatory Damage by Maintaining Intestinal Stem Cell Homeostasis and Barrier Integrity.
Volume: 49
Issue: 2
Pages: 353-362.e5
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35177769 | J:321512
First Author: Nguyen Ho-Bouldoires TH
Year: 2022
Journal: Commun Biol
Title: Ret kinase-mediated mechanical induction of colon stem cells by tumor growth pressure stimulates cancer progression in vivo.
Volume: 5
Issue: 1
Pages: 137
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36321561 | J:331877
First Author: van Neerven SM
Year: 2022
Journal: EMBO Mol Med
Title: Intestinal Apc-inactivation induces HSP25 dependency.
Volume: 14
Issue: 12
Pages: e16194
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29853607 | J:264047
First Author: Buczacki SJA
Year: 2018
Journal: J Exp Med
Title: Itraconazole targets cell cycle heterogeneity in colorectal cancer.
Volume: 215
Issue: 7
Pages: 1891-1912
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24019538 | J:201737
First Author: Niessen MT
Year: 2013
Journal: J Cell Biol
Title: aPKCλ controls epidermal homeostasis and stem cell fate through regulation of division orientation.
Volume: 202
Issue: 6
Pages: 887-900
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26631266 | J:227330
First Author: Davidson LA
Year: 2015
Journal: Cancer Res
Title: Targeted Deletion of p53 in Lgr5-Expressing Intestinal Stem Cells Promotes Colon Tumorigenesis in a Preclinical Model of Colitis-Associated Cancer.
Volume: 75
Issue: 24
Pages: 5392-7
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24637118 | J:209593
First Author: Sheaffer KL
Year: 2014
Journal: Genes Dev
Title: DNA methylation is required for the control of stem cell differentiation in the small intestine.
Volume: 28
Issue: 6
Pages: 652-64
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30449703 | J:285672
First Author: Bohin N
Year: 2018
Journal: Stem Cell Reports
Title: Genome Toxicity and Impaired Stem Cell Function after Conditional Activation of CreERT2 in the Intestine.
Volume: 11
Issue: 6
Pages: 1337-1346
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35523143 | J:355086
First Author: Jacob JM
Year: 2022
Journal: Cell Stem Cell
Title: PDGFRα-induced stromal maturation is required to restrain postnatal intestinal epithelial stemness and promote defense mechanisms.
Volume: 29
Issue: 5
Pages: 856-868.e5
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Publication
32796887 | J:294902
First Author: Kotani T
Year: 2020
Journal: Sci Rep
Title: Regulation of colonic epithelial cell homeostasis by mTORC1.
Volume: 10
Issue: 1
Pages: 13810
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27797821 | J:238856
First Author: Miyoshi H
Year: 2017
Journal: EMBO J
Title: Prostaglandin E2 promotes intestinal repair through an adaptive cellular response of the epithelium.
Volume: 36
Issue: 1
Pages: 5-24
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