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Search results 201 to 300 out of 326 for Lrrk2

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Category: Publication
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Type Details Score
Publication
- | J:161656
     
First Author: Farrer MJ
Year: 2010
Journal: MGI Direct Data Submission
Title: LRRK2 WT BAC transgenic strain.
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Publication
- | J:161657
     
First Author: Farrer MJ
Year: 2010
Journal: MGI Direct Data Submission
Title: LRRK2 GS G2019S transgenic strain
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Publication
33679324 | J:350644
 
First Author: Kuhlmann N
Year: 2021
Journal: Front Cell Neurosci
Title: Chronic and Acute Manipulation of Cortical Glutamate Transmission Induces Structural and Synaptic Changes in Co-cultured Striatal Neurons.
Volume: 15
Pages: 569031
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Publication
35732218 | J:332726
 
First Author: Hussein A
Year: 2022
Journal: Exp Neurol
Title: Cognitive deficits and altered cholinergic innervation in young adult male mice carrying a Parkinson's disease Lrrk2(G2019S) knockin mutation.
Volume: 355
Pages: 114145
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Publication
32477237 | J:310242
 
First Author: Crown LM
Year: 2020
Journal: Front Neurol
Title: Sleep Spindles and Fragmented Sleep as Prodromal Markers in a Preclinical Model of LRRK2-G2019S Parkinson's Disease.
Volume: 11
Pages: 324
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Publication
28330897 | J:250233
First Author: Wang H
Year: 2017
Journal: J Immunol
Title: Rip2 Is Required for Nod2-Mediated Lysozyme Sorting in Paneth Cells.
Volume: 198
Issue: 9
Pages: 3729-3736
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Publication
34686322 | J:321159
First Author: Walter J
Year: 2021
Journal: Cell Rep
Title: The Parkinson's-disease-associated mutation LRRK2-G2019S alters dopaminergic differentiation dynamics via NR2F1.
Volume: 37
Issue: 3
Pages: 109864
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Publication
11004510 | J:66308
First Author: Takahashi Y
Year: 2000
Journal: Biochim Biophys Acta
Title: Identification of cAMP analogue inducible genes in RAW264 macrophages.
Volume: 1492
Issue: 2-3
Pages: 385-94
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Publication
29891719 | J:263756
First Author: Amin P
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Regulation of a distinct activated RIPK1 intermediate bridging complex I and complex II in TNFα-mediated apoptosis.
Volume: 115
Issue: 26
Pages: E5944-E5953
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Publication
- | J:101977
     
First Author: The Jackson Laboratory
Year: 2005
Journal: Unpublished
Title: Information obtained from The Jackson Laboratory, Bar Harbor, ME
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Publication
- | J:147112
     
First Author: Taconic
Year: 2006
Journal: MGI Direct Data Submission
Title: Information obtained from Taconic website.
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:157064
     
First Author: University of California, Davis
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the University of California, Davis
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Publication
- | J:342608
       
First Author: GO Central curators, GOA curators, Rhea curators
Year: 2020
Title: Automatic Gene Ontology annotation based on Rhea mapping
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Publication
- | J:73065
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
- | J:84900
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
23455607 | J:194153
First Author: Orenstein SJ
Year: 2013
Journal: Nat Neurosci
Title: Interplay of LRRK2 with chaperone-mediated autophagy.
Volume: 16
Issue: 4
Pages: 394-406
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Publication
37876795 | J:351289
First Author: He KJ
Year: 2023
Journal: iScience
Title: LRRK2 G2019S promotes astrocytic inflammation induced by oligomeric α-synuclein through NF-κB pathway.
Volume: 26
Issue: 11
Pages: 108130
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Publication
24075941 | J:204058
First Author: Häbig K
Year: 2013
Journal: Biochim Biophys Acta
Title: LRRK2 guides the actin cytoskeleton at growth cones together with ARHGEF7 and Tropomyosin 4.
Volume: 1832
Issue: 12
Pages: 2352-67
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Publication
28973420 | J:251668
First Author: Chen Z
Year: 2017
Journal: Hum Mol Genet
Title: LRRK2 interacts with ATM and regulates Mdm2-p53 cell proliferation axis in response to genotoxic stress.
Volume: 26
Issue: 22
Pages: 4494-4505
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Publication
26341487 | J:237016
First Author: Melrose HL
Year: 2015
Journal: Biochem J
Title: LRRK2 and ubiquitination: implications for kinase inhibitor therapy.
Volume: 470
Issue: 3
Pages: e21-4
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25899482 | J:244388
First Author: Wallings R
Year: 2015
Journal: FEBS J
Title: Cellular processes associated with LRRK2 function and dysfunction.
Volume: 282
Issue: 15
Pages: 2806-26
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Publication
- | J:169825
     
First Author: Li C
Year: 2011
Journal: MGI Direct Data Submission
Title: A new transgenic mouse expressing mutant human LRRK2 (G2019S), a model for Parkinson's disease
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Publication
24830390 | J:214322
 
First Author: Chou JS
Year: 2014
Journal: Neurobiol Dis
Title: (G2019S) LRRK2 causes early-phase dysfunction of SNpc dopaminergic neurons and impairment of corticostriatal long-term depression in the PD transgenic mouse.
Volume: 68
Pages: 190-9
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Publication
20659558 | J:163737
First Author: Melrose HL
Year: 2010
Journal: Neurobiol Dis
Title: Impaired dopaminergic neurotransmission and microtubule-associated protein tau alterations in human LRRK2 transgenic mice.
Volume: 40
Issue: 3
Pages: 503-17
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Publication
34515301 | J:315839
First Author: Tasegian A
Year: 2021
Journal: Biochem J
Title: Impact of Type II LRRK2 inhibitors on signaling and mitophagy.
Volume: 478
Issue: 19
Pages: 3555-3573
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33720852 | J:347644
First Author: Henderson MX
Year: 2021
Journal: J Parkinsons Dis
Title: LRRK2 Kinase Activity Does Not Alter Cell-Autonomous Tau Pathology Development in Primary Neurons.
Volume: 11
Issue: 3
Pages: 1187-1196
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Publication
26930193 | J:259816
First Author: Shu Y
Year: 2016
Journal: PLoS One
Title: Parkinson-Related LRRK2 Mutation R1628P Enables Cdk5 Phosphorylation of LRRK2 and Upregulates Its Kinase Activity.
Volume: 11
Issue: 3
Pages: e0149739
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Publication
25804954 | J:221597
First Author: Mikhail F
Year: 2015
Journal: Hum Mol Genet
Title: Lack of exacerbation of neurodegeneration in a double transgenic mouse model of mutant LRRK2 and tau.
Volume: 24
Issue: 12
Pages: 3545-56
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Publication
38227290 | J:344326
 
First Author: Eguchi T
Year: 2024
Journal: J Cell Biol
Title: The V-ATPase-ATG16L1 axis recruits LRRK2 to facilitate the lysosomal stress response.
Volume: 223
Issue: 3
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20173330 | J:196352
First Author: Hsu CH
Year: 2010
Journal: Neurodegener Dis
Title: LRRK2 and the stress response: interaction with MKKs and JNK-interacting proteins.
Volume: 7
Issue: 1-3
Pages: 68-75
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28958936 | J:253289
First Author: Kim J
Year: 2017
Journal: Biochem Biophys Res Commun
Title: Suppression of neuroinflammation by matrix metalloproteinase-8 inhibitor in aged normal and LRRK2 G2019S Parkinson's disease model mice challenged with lipopolysaccharide.
Volume: 493
Issue: 2
Pages: 879-886
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Publication
- | J:314235
     
First Author: Mazza MC
Year: 2020
Journal: bioRxiv
Title: Combined knockout of Lrrk2 and Rab29 does not result in behavioral abnormalities in vivo
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Publication
24993787 | J:215453
First Author: Li T
Year: 2014
Journal: Hum Mol Genet
Title: Novel LRRK2 GTP-binding inhibitors reduced degeneration in Parkinson's disease cell and mouse models.
Volume: 23
Issue: 23
Pages: 6212-22
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Publication
30808409 | J:278978
First Author: Henderson MX
Year: 2019
Journal: Acta Neuropathol Commun
Title: LRRK2 inhibition does not impart protection from α-synuclein pathology and neuron death in non-transgenic mice.
Volume: 7
Issue: 1
Pages: 28
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28321439 | J:255948
 
First Author: Xiong Y
Year: 2017
Journal: eNeuro
Title: Overexpression of Parkinson's Disease-Associated Mutation LRRK2 G2019S in Mouse Forebrain Induces Behavioral Deficits and α-Synuclein Pathology.
Volume: 4
Issue: 2
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22649237 | J:184970
First Author: Friedman LG
Year: 2012
Journal: J Neurosci
Title: Disrupted autophagy leads to dopaminergic axon and dendrite degeneration and promotes presynaptic accumulation of α-synuclein and LRRK2 in the brain.
Volume: 32
Issue: 22
Pages: 7585-93
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25174890 | J:218456
 
First Author: Tsika E
Year: 2014
Journal: Neurobiol Dis
Title: Conditional expression of Parkinson's disease-related R1441C LRRK2 in midbrain dopaminergic neurons of mice causes nuclear abnormalities without neurodegeneration.
Volume: 71
Pages: 345-58
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35776681 | J:327105
 
First Author: Lara Ordóñez AJ
Year: 2022
Journal: Biol Open
Title: The LRRK2 signaling network converges on a centriolar phospho-Rab10/RILPL1 complex to cause deficits in centrosome cohesion and cell polarization.
Volume: 11
Issue: 8
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33653948 | J:304788
 
First Author: Sobu Y
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Pathogenic LRRK2 regulates ciliation probability upstream of tau tubulin kinase 2 via Rab10 and RILPL1 proteins.
Volume: 118
Issue: 10
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25076905 | J:310233
 
First Author: Alvarez-Castelao B
Year: 2014
Journal: Front Aging Neurosci
Title: Epitope Mapping of Antibodies to Alpha-Synuclein in LRRK2 Mutation Carriers, Idiopathic Parkinson Disease Patients, and Healthy Controls.
Volume: 6
Pages: 169
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Publication
27890708 | -
 
First Author: Ding X
Year: 2017
Journal: Neurobiol Dis
Title: Fbxl18 targets LRRK2 for proteasomal degradation and attenuates cell toxicity.
Volume: 98
Pages: 122-136
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26407721 | J:302951
First Author: Fell MJ
Year: 2015
Journal: J Pharmacol Exp Ther
Title: MLi-2, a Potent, Selective, and Centrally Active Compound for Exploring the Therapeutic Potential and Safety of LRRK2 Kinase Inhibition.
Volume: 355
Issue: 3
Pages: 397-409
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18650931 | -
First Author: Gotthardt K
Year: 2008
Journal: EMBO J
Title: Structure of the Roc-COR domain tandem of C. tepidum, a prokaryotic homologue of the human LRRK2 Parkinson kinase.
Volume: 27
Issue: 16
Pages: 2239-49
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34530877 | J:313813
First Author: Kadgien CA
Year: 2021
Journal: Mol Brain
Title: Endosomal traffic and glutamate synapse activity are increased in VPS35 D620N mutant knock-in mouse neurons, and resistant to LRRK2 kinase inhibition.
Volume: 14
Issue: 1
Pages: 143
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16532471 | -
First Author: Galter D
Year: 2006
Journal: Ann Neurol
Title: LRRK2 expression linked to dopamine-innervated areas.
Volume: 59
Issue: 4
Pages: 714-9
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15541309 | -
First Author: Zimprich A
Year: 2004
Journal: Neuron
Title: Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology.
Volume: 44
Issue: 4
Pages: 601-7
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- | J:177258
     
First Author: Ouyang Y
Year: 2011
Journal: MGI Direct Data Submission
Title: Creation of a transgenic mouse expressing human LRRK2
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25360523 | -
First Author: Waschbüsch D
Year: 2014
Journal: PLoS One
Title: LRRK2 transport is regulated by its novel interacting partner Rab32.
Volume: 9
Issue: 10
Pages: e111632
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16487147 | -
First Author: Simón-Sánchez J
Year: 2006
Journal: Eur J Neurosci
Title: LRRK2 is expressed in areas affected by Parkinson's disease in the adult mouse brain.
Volume: 23
Issue: 3
Pages: 659-66
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17447891 | -
First Author: Jaleel M
Year: 2007
Journal: Biochem J
Title: LRRK2 phosphorylates moesin at threonine-558: characterization of how Parkinson's disease mutants affect kinase activity.
Volume: 405
Issue: 2
Pages: 307-17
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20642453 | -
First Author: Nichols RJ
Year: 2010
Journal: Biochem J
Title: 14-3-3 binding to LRRK2 is disrupted by multiple Parkinson's disease-associated mutations and regulates cytoplasmic localization.
Volume: 430
Issue: 3
Pages: 393-404
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26268594 | -
First Author: Shanley MR
Year: 2015
Journal: Biochemistry
Title: LRRK2 Facilitates tau Phosphorylation through Strong Interaction with tau and cdk5.
Volume: 54
Issue: 33
Pages: 5198-208
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20876399 | -
First Author: Meixner A
Year: 2011
Journal: Mol Cell Proteomics
Title: A QUICK screen for Lrrk2 interaction partners--leucine-rich repeat kinase 2 is involved in actin cytoskeleton dynamics.
Volume: 10
Issue: 1
Pages: M110.001172
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21850687 | -
First Author: Angeles DC
Year: 2011
Journal: Hum Mutat
Title: Mutations in LRRK2 increase phosphorylation of peroxiredoxin 3 exacerbating oxidative stress-induced neuronal death.
Volume: 32
Issue: 12
Pages: 1390-7
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23183827 | -
First Author: Guerreiro PS
Year: 2013
Journal: J Mol Med (Berl)
Title: LRRK2 interactions with α-synuclein in Parkinson's disease brains and in cell models.
Volume: 91
Issue: 4
Pages: 513-22
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Publication
32422864 | J:302660
 
First Author: Sim H
Year: 2020
Journal: Int J Mol Sci
Title: Iroquois Homeobox Protein 2 Identified as a Potential Biomarker for Parkinson's Disease.
Volume: 21
Issue: 10
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Publication
20949042 | -
First Author: Zach S
Year: 2010
Journal: PLoS One
Title: Signal transduction protein array analysis links LRRK2 to Ste20 kinases and PKC zeta that modulate neuronal plasticity.
Volume: 5
Issue: 10
Pages: e13191
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Publication
18230735 | -
First Author: Deng J
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Structure of the ROC domain from the Parkinson's disease-associated leucine-rich repeat kinase 2 reveals a dimeric GTPase.
Volume: 105
Issue: 5
Pages: 1499-504
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Publication
27063942 | J:230487
 
First Author: Palomo-Garo C
Year: 2016
Journal: Pharmacol Res
Title: Targeting the cannabinoid CB2 receptor to attenuate the progression of motor deficits in LRRK2-transgenic mice.
Volume: 110
Pages: 181-192
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•
•
Publication
31346295 | J:279709
First Author: Henderson MX
Year: 2019
Journal: Nat Neurosci
Title: Spread of α-synuclein pathology through the brain connectome is modulated by selective vulnerability and predicted by network analysis.
Volume: 22
Issue: 8
Pages: 1248-1257
•
•
•
•
•
Publication
19503083 | J:149135
First Author: Li Y
Year: 2009
Journal: Nat Neurosci
Title: Mutant LRRK2(R1441G) BAC transgenic mice recapitulate cardinal features of Parkinson's disease.
Volume: 12
Issue: 7
Pages: 826-8
•
•
•
•
•
Publication
31148170 | J:277683
First Author: Marte A
Year: 2019
Journal: J Neurochem
Title: Leucine-rich repeat kinase 2 phosphorylation on synapsin I regulates glutamate release at pre-synaptic sites.
Volume: 150
Issue: 3
Pages: 264-281
•
•
•
•
•
Publication
21494637 | J:171645
First Author: Ramonet D
Year: 2011
Journal: PLoS One
Title: Dopaminergic neuronal loss, reduced neurite complexity and autophagic abnormalities in transgenic mice expressing G2019S mutant LRRK2.
Volume: 6
Issue: 4
Pages: e18568
•
•
•
•
•
Publication
22342962 | J:184728
 
First Author: Gillardon F
Year: 2012
Journal: Neuroscience
Title: Parkinson's disease-linked leucine-rich repeat kinase 2(R1441G) mutation increases proinflammatory cytokine release from activated primary microglial cells and resultant neurotoxicity.
Volume: 208
Pages: 41-8
•
•
•
•
•
Publication
26192625 | J:222393
 
First Author: Tagliaferro P
Year: 2015
Journal: Neurobiol Dis
Title: An early axonopathy in a hLRRK2(R1441G) transgenic model of Parkinson disease.
Volume: 82
Pages: 359-371
•
•
•
•
•




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