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Search results 201 to 300 out of 557 for Nf1

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Category: Publication
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Type Details Score
Publication
38913608 | J:351139
First Author: O'Donohue AK
Year: 2024
Journal: PLoS One
Title: Dietary intervention rescues a bone porosity phenotype in a murine model of Neurofibromatosis Type 1 (NF1).
Volume: 19
Issue: 6
Pages: e0304778
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Publication
20410111 | J:159840
First Author: Brown JA
Year: 2010
Journal: J Neurosci
Title: Defective cAMP generation underlies the sensitivity of CNS neurons to neurofibromatosis-1 heterozygosity.
Volume: 30
Issue: 16
Pages: 5579-89
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Publication
23221341 | J:194157
First Author: Jessen WJ
Year: 2013
Journal: J Clin Invest
Title: MEK inhibition exhibits efficacy in human and mouse neurofibromatosis tumors.
Volume: 123
Issue: 1
Pages: 340-7
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Publication
22307743 | J:211765
First Author: Alanne MH
Year: 2012
Journal: J Cell Biochem
Title: Phenotypic characterization of transgenic mice harboring Nf1+/- or Nf1-/- osteoclasts in otherwise Nf1+/+ background.
Volume: 113
Issue: 6
Pages: 2136-46
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Publication
21319287 | J:215873
First Author: Wu J
Year: 2012
Journal: Pediatr Blood Cancer
Title: Preclincial testing of sorafenib and RAD001 in the Nf(flox/flox) ;DhhCre mouse model of plexiform neurofibroma using magnetic resonance imaging.
Volume: 58
Issue: 2
Pages: 173-80
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Publication
24997609 | J:227603
First Author: de la Croix Ndong J
Year: 2014
Journal: Nat Med
Title: Asfotase-α improves bone growth, mineralization and strength in mouse models of neurofibromatosis type-1.
Volume: 20
Issue: 8
Pages: 904-10
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Publication
19574548 | J:164937
First Author: Xu J
Year: 2009
Journal: Circ Res
Title: Cardiomyocyte-specific loss of neurofibromin promotes cardiac hypertrophy and dysfunction.
Volume: 105
Issue: 3
Pages: 304-11
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Publication
20124472 | J:157155
First Author: Banerjee S
Year: 2010
Journal: Cancer Res
Title: The neurofibromatosis type 1 tumor suppressor controls cell growth by regulating signal transducer and activator of transcription-3 activity in vitro and in vivo.
Volume: 70
Issue: 4
Pages: 1356-66
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Publication
14523097 | J:120166
First Author: Dasgupta B
Year: 2003
Journal: J Neurosci
Title: The neurofibromatosis 1 gene product neurofibromin regulates pituitary adenylate cyclase-activating polypeptide-mediated signaling in astrocytes.
Volume: 23
Issue: 26
Pages: 8949-54
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Publication
32810864 | J:295936
First Author: Vasiljevski ER
Year: 2020
Journal: PLoS One
Title: Evaluating modified diets and dietary supplement therapies for reducing muscle lipid accumulation and improving muscle function in neurofibromatosis type 1 (NF1).
Volume: 15
Issue: 8
Pages: e0237097
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Publication
33293695 | J:301473
First Author: Na Y
Year: 2021
Journal: Oncogene
Title: MicroRNA-155 contributes to plexiform neurofibroma growth downstream of MEK.
Volume: 40
Issue: 5
Pages: 951-963
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Publication
19191334 | J:156205
First Author: Yeh TH
Year: 2009
Journal: Glia
Title: Microarray analyses reveal regional astrocyte heterogeneity with implications for neurofibromatosis type 1 (NF1)-regulated glial proliferation.
Volume: 57
Issue: 11
Pages: 1239-49
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Publication
11751683 | J:73716
First Author: Gutmann DH
Year: 2001
Journal: Hum Mol Genet
Title: Heterozygosity for the neurofibromatosis 1 (NF1) tumor suppressor results in abnormalities in cell attachment, spreading and motility in astrocytes.
Volume: 10
Issue: 26
Pages: 3009-16
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Publication
39106942 | J:353293
 
First Author: Wu C
Year: 2024
Journal: Exp Neurol
Title: Investigating therapeutic nonsense suppression in a neurofibromatosis mouse model.
Volume: 380
Pages: 114914
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Publication
35589737 | J:324999
First Author: Anastasaki C
Year: 2022
Journal: Nat Commun
Title: Neuronal hyperexcitability drives central and peripheral nervous system tumor progression in models of neurofibromatosis-1.
Volume: 13
Issue: 1
Pages: 2785
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Publication
1946382 | J:31498
First Author: Gutmann DH
Year: 1991
Journal: Proc Natl Acad Sci U S A
Title: Identification of the neurofibromatosis type 1 gene product.
Volume: 88
Issue: 21
Pages: 9658-62
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8314000 | J:16739
First Author: Huynh DP
Year: 1994
Journal: Dev Biol
Title: Differential expression and tissue distribution of type I and type II neurofibromins during mouse fetal development.
Volume: 161
Issue: 2
Pages: 538-51
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7633452 | J:25208
First Author: Danglot G
Year: 1995
Journal: Hum Mol Genet
Title: Neurofibromatosis 1 (NF1) mRNAs expressed in the central nervous system are differentially spliced in the 5' part of the gene.
Volume: 4
Issue: 5
Pages: 915-20
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Publication
7568895 | J:30191
 
First Author: Gutmann DH
Year: 1995
Journal: Prog Brain Res
Title: Expression of the neurofibromatosis type 1 (NF1) gene during mouse embryonic development.
Volume: 105
Pages: 327-35
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Publication
19074905 | J:142234
First Author: Daginakatte GC
Year: 2008
Journal: Cancer Res
Title: Increased c-Jun-NH2-kinase signaling in neurofibromatosis-1 heterozygous microglia drives microglia activation and promotes optic glioma proliferation.
Volume: 68
Issue: 24
Pages: 10358-66
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Publication
27283753 | J:243903
First Author: Petrella LI
Year: 2016
Journal: Genes Brain Behav
Title: Brain and behaviour phenotyping of a mouse model of neurofibromatosis type-1: an MRI/DTI study on social cognition.
Volume: 15
Issue: 7
Pages: 637-46
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Publication
12881715 | J:84658
First Author: Gutmann DH
Year: 2003
Journal: Oncogene
Title: Mlh1 deficiency accelerates myeloid leukemogenesis in neurofibromatosis 1 (Nf1) heterozygous mice.
Volume: 22
Issue: 29
Pages: 4581-5
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Publication
16271875 | J:103691
First Author: Li W
Year: 2005
Journal: Curr Biol
Title: The HMG-CoA reductase inhibitor lovastatin reverses the learning and attention deficits in a mouse model of neurofibromatosis type 1.
Volume: 15
Issue: 21
Pages: 1961-7
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Publication
29162814 | J:257198
First Author: Ma Z
Year: 2017
Journal: Nat Commun
Title: TrkB dependent adult hippocampal progenitor differentiation mediates sustained ketamine antidepressant response.
Volume: 8
Issue: 1
Pages: 1668
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Publication
25381154 | J:218215
First Author: Warrington NM
Year: 2015
Journal: Cancer Res
Title: The cyclic AMP pathway is a sex-specific modifier of glioma risk in type I neurofibromatosis patients.
Volume: 75
Issue: 1
Pages: 16-21
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Publication
20876733 | J:164880
First Author: Lee DY
Year: 2010
Journal: Genes Dev
Title: Neurofibromatosis-1 regulates neuroglial progenitor proliferation and glial differentiation in a brain region-specific manner.
Volume: 24
Issue: 20
Pages: 2317-29
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Publication
22851646 | J:193516
First Author: Wallace MD
Year: 2012
Journal: Genetics
Title: Comparative oncogenomics implicates the neurofibromin 1 gene (NF1) as a breast cancer driver.
Volume: 192
Issue: 2
Pages: 385-96
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Publication
12082543 | J:77141
First Author: Gutmann DH
Year: 2002
Journal: Neoplasia
Title: Mouse models of neurofibromatosis 1 and 2.
Volume: 4
Issue: 4
Pages: 279-90
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Publication
22751498 | J:185345
First Author: Stowe IB
Year: 2012
Journal: Genes Dev
Title: A shared molecular mechanism underlies the human rasopathies Legius syndrome and Neurofibromatosis-1.
Volume: 26
Issue: 13
Pages: 1421-6
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Publication
20307317 | J:159679
 
First Author: Pemov A
Year: 2010
Journal: BMC Genomics
Title: Evidence of perturbations of cell cycle and DNA repair pathways as a consequence of human and murine NF1-haploinsufficiency.
Volume: 11
Pages: 194
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Publication
24465906 | J:212331
First Author: Kühnisch J
Year: 2014
Journal: PLoS One
Title: Multiscale, converging defects of macro-porosity, microstructure and matrix mineralization impact long bone fragility in NF1.
Volume: 9
Issue: 1
Pages: e86115
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Publication
29032173 | J:256981
 
First Author: Tahaei SE
Year: 2018
Journal: Bone
Title: The reduced osteogenic potential of Nf1-deficient osteoprogenitors is EGFR-independent.
Volume: 106
Pages: 103-111
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Publication
29228356 | J:257000
First Author: Summers MA
Year: 2018
Journal: Hum Mol Genet
Title: Dietary intervention rescues myopathy associated with neurofibromatosis type 1.
Volume: 27
Issue: 4
Pages: 577-588
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24947449 | J:215491
 
First Author: Kühnisch J
Year: 2014
Journal: Bone
Title: Neurofibromin inactivation impairs osteocyte development in Nf1Prx1 and Nf1Col1 mouse models.
Volume: 66
Pages: 155-62
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Publication
33743598 | J:352980
First Author: Rahn RM
Year: 2021
Journal: J Neurodev Disord
Title: Shared developmental gait disruptions across two mouse models of neurodevelopmental disorders.
Volume: 13
Issue: 1
Pages: 10
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32527982 | J:291540
First Author: van Lier M
Year: 2020
Journal: J Neurosci
Title: Disruption of Critical Period Plasticity in a Mouse Model of Neurofibromatosis Type 1.
Volume: 40
Issue: 28
Pages: 5495-5509
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Publication
17096025 | J:139277
First Author: Shapira S
Year: 2007
Journal: Cell Death Differ
Title: The tumor suppressor neurofibromin confers sensitivity to apoptosis by Ras-dependent and Ras-independent pathways.
Volume: 14
Issue: 5
Pages: 895-906
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39100928 | J:357394
First Author: Patritti-Cram J
Year: 2024
Journal: iScience
Title: NF1-dependent disruption of the blood-nerve-barrier is improved by blockade of P2RY14.
Volume: 27
Issue: 7
Pages: 110294
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10591652 | J:58876
First Author: Cichowski K
Year: 1999
Journal: Science
Title: Mouse models of tumor development in neurofibromatosis type 1.
Volume: 286
Issue: 5447
Pages: 2172-6
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30542122 | J:295096
First Author: Fletcher JS
Year: 2019
Journal: Oncogene
Title: STAT3 inhibition reduces macrophage number and tumor growth in neurofibroma.
Volume: 38
Issue: 15
Pages: 2876-2884
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18984156 | J:147615
First Author: Yang FC
Year: 2008
Journal: Cell
Title: Nf1-dependent tumors require a microenvironment containing Nf1+/-- and c-kit-dependent bone marrow.
Volume: 135
Issue: 3
Pages: 437-48
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18477655 | J:152129
First Author: Nagasubramanian R
Year: 2008
Journal: Mutagenesis
Title: Survival and tumorigenesis in O6-methylguanine DNA methyltransferase-deficient mice following cyclophosphamide exposure.
Volume: 23
Issue: 5
Pages: 341-6
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Publication
24370551 | J:219312
First Author: Li F
Year: 2014
Journal: Circulation
Title: Neurofibromin-deficient myeloid cells are critical mediators of aneurysm formation in vivo.
Volume: 129
Issue: 11
Pages: 1213-24
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Publication
18218617 | J:135289
First Author: Patrakitkomjorn S
Year: 2008
Journal: J Biol Chem
Title: Neurofibromatosis type 1 (NF1) tumor suppressor, neurofibromin, regulates the neuronal differentiation of PC12 cells via its associating protein, CRMP-2.
Volume: 283
Issue: 14
Pages: 9399-413
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Publication
19477430 | J:149662
First Author: Wang Y
Year: 2009
Journal: Cancer Cell
Title: Expression of mutant p53 proteins implicates a lineage relationship between neural stem cells and malignant astrocytic glioma in a murine model.
Volume: 15
Issue: 6
Pages: 514-26
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26764354 | J:232645
First Author: Liu YL
Year: 2016
Journal: Blood
Title: Timing of the loss of Pten protein determines disease severity in a mouse model of myeloid malignancy.
Volume: 127
Issue: 15
Pages: 1912-22
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29596064 | J:265441
First Author: Liao CP
Year: 2018
Journal: J Clin Invest
Title: Contributions of inflammation and tumor microenvironment to neurofibroma tumorigenesis.
Volume: 128
Issue: 7
Pages: 2848-2861
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Publication
18451155 | J:134611
First Author: Kwon CH
Year: 2008
Journal: Cancer Res
Title: Pten haploinsufficiency accelerates formation of high-grade astrocytomas.
Volume: 68
Issue: 9
Pages: 3286-94
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Publication
25119042 | J:217077
First Author: De Raedt T
Year: 2014
Journal: Nature
Title: PRC2 loss amplifies Ras-driven transcription and confers sensitivity to BRD4-based therapies.
Volume: 514
Issue: 7521
Pages: 247-51
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9214616 | J:41126
First Author: Weiss WA
Year: 1997
Journal: EMBO J
Title: Targeted expression of MYCN causes neuroblastoma in transgenic mice.
Volume: 16
Issue: 11
Pages: 2985-95
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16405917 | J:104986
First Author: Boyanapalli M
Year: 2006
Journal: Biochem Biophys Res Commun
Title: Neurofibromin binds to caveolin-1 and regulates ras, FAK, and Akt.
Volume: 340
Issue: 4
Pages: 1200-8
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Publication
26002977 | J:320357
First Author: Lubeck BA
Year: 2015
Journal: J Immunol
Title: Cutting Edge: Codeletion of the Ras GTPase-Activating Proteins (RasGAPs) Neurofibromin 1 and p120 RasGAP in T Cells Results in the Development of T Cell Acute Lymphoblastic Leukemia.
Volume: 195
Issue: 1
Pages: 31-5
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Publication
23144792 | J:194861
First Author: He Y
Year: 2012
Journal: PLoS One
Title: c-Fms signaling mediates neurofibromatosis Type-1 osteoclast gain-in-functions.
Volume: 7
Issue: 11
Pages: e46900
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Publication
16648142 | J:109532
First Author: Munchhof AM
Year: 2006
Journal: Hum Mol Genet
Title: Neurofibroma-associated growth factors activate a distinct signaling network to alter the function of neurofibromin-deficient endothelial cells.
Volume: 15
Issue: 11
Pages: 1858-69
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26000738 | J:224780
First Author: Mroue R
Year: 2015
Journal: PLoS Genet
Title: Monoallelic loss of the imprinted gene Grb10 promotes tumor formation in irradiated Nf1+/- mice.
Volume: 11
Issue: 5
Pages: e1005235
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18614544 | J:138868
First Author: Hegedus B
Year: 2008
Journal: Hum Mol Genet
Title: Neurofibromin regulates somatic growth through the hypothalamic-pituitary axis.
Volume: 17
Issue: 19
Pages: 2956-66
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15371411 | J:94906
First Author: Zhu C
Year: 2004
Journal: J Biol Chem
Title: The interferon consensus sequence-binding protein activates transcription of the gene encoding neurofibromin 1.
Volume: 279
Issue: 49
Pages: 50874-85
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18316617 | J:132860
First Author: Hegedus B
Year: 2008
Journal: Cancer Res
Title: Preclinical cancer therapy in a mouse model of neurofibromatosis-1 optic glioma.
Volume: 68
Issue: 5
Pages: 1520-8
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Publication
26965285 | J:231912
First Author: Akutagawa J
Year: 2016
Journal: Leukemia
Title: Targeting the PI3K/Akt pathway in murine MDS/MPN driven by hyperactive Ras.
Volume: 30
Issue: 6
Pages: 1335-43
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Publication
32471868 | J:297150
First Author: Mund JA
Year: 2020
Journal: J Biol Chem
Title: Genetic disruption of the small GTPase RAC1 prevents plexiform neurofibroma formation in mice with neurofibromatosis type 1
Volume: 295
Issue: 29
Pages: 9948-9958
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25616962 | J:220867
First Author: Karolak MR
Year: 2015
Journal: Hum Mol Genet
Title: FGFR1 signaling in hypertrophic chondrocytes is attenuated by the Ras-GAP neurofibromin during endochondral bone formation.
Volume: 24
Issue: 9
Pages: 2552-64
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15665300 | J:95509
First Author: Dasgupta B
Year: 2005
Journal: Cancer Res
Title: Glioma formation in neurofibromatosis 1 reflects preferential activation of K-RAS in astrocytes.
Volume: 65
Issue: 1
Pages: 236-45
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15805275 | J:97360
First Author: Dasgupta B
Year: 2005
Journal: Cancer Res
Title: Proteomic analysis reveals hyperactivation of the mammalian target of rapamycin pathway in neurofibromatosis 1-associated human and mouse brain tumors.
Volume: 65
Issue: 7
Pages: 2755-60
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Publication
31600280 | J:281157
First Author: Sutton LP
Year: 2019
Journal: PLoS Biol
Title: NF1-cAMP signaling dissociates cell type-specific contributions of striatal medium spiny neurons to reward valuation and motor control.
Volume: 17
Issue: 10
Pages: e3000477
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Publication
24710274 | J:221628
First Author: Hinman MN
Year: 2014
Journal: Mol Cell Biol
Title: Neurofibromatosis type 1 alternative splicing is a key regulator of Ras signaling in neurons.
Volume: 34
Issue: 12
Pages: 2188-97
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Publication
24573885 | J:313453
First Author: Zhou P
Year: 2014
Journal: Mol Cell Biochem
Title: Down-regulated Six2 by knockdown of neurofibromin results in apoptosis of metanephric mesenchyme cells in vitro.
Volume: 390
Issue: 1-2
Pages: 205-13
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21642990 | J:176182
First Author: Mavrakis KJ
Year: 2011
Journal: Nat Genet
Title: A cooperative microRNA-tumor suppressor gene network in acute T-cell lymphoblastic leukemia (T-ALL).
Volume: 43
Issue: 7
Pages: 673-8
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Publication
25246577 | J:216462
First Author: Galvao RP
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Transformation of quiescent adult oligodendrocyte precursor cells into malignant glioma through a multistep reactivation process.
Volume: 111
Issue: 40
Pages: E4214-23
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20233966 | J:161558
First Author: Wong JC
Year: 2010
Journal: Blood
Title: Use of chromosome engineering to model a segmental deletion of chromosome band 7q22 found in myeloid malignancies.
Volume: 115
Issue: 22
Pages: 4524-32
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22810304 | J:196495
First Author: Deo M
Year: 2013
Journal: J Invest Dermatol
Title: Differential effects of neurofibromin gene dosage on melanocyte development.
Volume: 133
Issue: 1
Pages: 49-58
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Publication
33531372 | J:305587
First Author: Sutcliffe MD
Year: 2021
Journal: Cancer Res
Title: Premalignant Oligodendrocyte Precursor Cells Stall in a Heterogeneous State of Replication Stress Prior to Gliomagenesis.
Volume: 81
Issue: 7
Pages: 1868-1882
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10973261 | J:64364
First Author: Reilly KM
Year: 2000
Journal: Nat Genet
Title: Nf1;Trp53 mutant mice develop glioblastoma with evidence of strain-specific effects.
Volume: 26
Issue: 1
Pages: 109-13
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Publication
16397217 | J:105038
First Author: Reilly KM
Year: 2006
Journal: Cancer Res
Title: An imprinted locus epistatically influences Nstr1 and Nstr2 to control resistance to nerve sheath tumors in a neurofibromatosis type 1 mouse model.
Volume: 66
Issue: 1
Pages: 62-8
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Publication
28646022 | J:243271
First Author: Dodd RD
Year: 2017
Journal: Cancer Res
Title: NF1+/- Hematopoietic Cells Accelerate Malignant Peripheral Nerve Sheath Tumor Development without Altering Chemotherapy Response.
Volume: 77
Issue: 16
Pages: 4486-4497
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Publication
22105171 | J:184421
First Author: Wang HF
Year: 2011
Journal: J Clin Invest
Title: Valosin-containing protein and neurofibromin interact to regulate dendritic spine density.
Volume: 121
Issue: 12
Pages: 4820-37
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32816910 | J:301622
First Author: Chaney KE
Year: 2020
Journal: Cancer Res
Title: Cdkn2a Loss in a Model of Neurofibroma Demonstrates Stepwise Tumor Progression to Atypical Neurofibroma and MPNST.
Volume: 80
Issue: 21
Pages: 4720-4730
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29720369 | J:263941
First Author: Peacock JD
Year: 2018
Journal: Cancer Res
Title: Genomic Status of MET Potentiates Sensitivity to MET and MEK Inhibition in NF1-Related Malignant Peripheral Nerve Sheath Tumors.
Volume: 78
Issue: 13
Pages: 3672-3687
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Publication
31091306 | J:309032
First Author: Rhodes SD
Year: 2019
Journal: Hum Mol Genet
Title: Cdkn2a (Arf) loss drives NF1-associated atypical neurofibroma and malignant transformation.
Volume: 28
Issue: 16
Pages: 2752-2762
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Publication
12154062 | J:78113
First Author: Li H
Year: 2002
Journal: Cancer Res
Title: Epidermal growth factor receptor signaling pathways are associated with tumorigenesis in the Nf1:p53 mouse tumor model.
Volume: 62
Issue: 15
Pages: 4507-13
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Publication
24755485 | J:210619
 
First Author: Duan JH
Year: 2014
Journal: Neuroscience
Title: N-type calcium current, Cav2.2, is enhanced in small-diameter sensory neurons isolated from Nf1+/- mice.
Volume: 270
Pages: 192-202
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Publication
23703870 | J:231256
First Author: Rhodes SD
Year: 2013
Journal: J Bone Miner Res
Title: Hyperactive transforming growth factor-β1 signaling potentiates skeletal defects in a neurofibromatosis type 1 mouse model.
Volume: 28
Issue: 12
Pages: 2476-89
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Publication
25043591 | J:324826
First Author: de la Croix Ndong J
Year: 2015
Journal: J Bone Miner Res
Title: Combined MEK inhibition and BMP2 treatment promotes osteoblast differentiation and bone healing in Nf1Osx -/- mice.
Volume: 30
Issue: 1
Pages: 55-63
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Publication
9778496 | J:50306
First Author: Lakkis MM
Year: 1998
Journal: Development
Title: Neurofibromin modulation of ras activity is required for normal endocardial-mesenchymal transformation in the developing heart.
Volume: 125
Issue: 22
Pages: 4359-67
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Publication
34475389 | J:311172
First Author: Schachter NF
Year: 2021
Journal: Nat Commun
Title: Single allele loss-of-function mutations select and sculpt conditional cooperative networks in breast cancer.
Volume: 12
Issue: 1
Pages: 5238
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Publication
22789544 | J:191011
First Author: Lee DY
Year: 2012
Journal: Cancer Cell
Title: Innate neural stem cell heterogeneity determines the patterning of glioma formation in children.
Volume: 22
Issue: 1
Pages: 131-8
•
•
•
•
•
Publication
19661150 | J:209264
First Author: Lin L
Year: 2009
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Mice lacking neurofibromin develop gastric hyperplasia.
Volume: 297
Issue: 4
Pages: G751-61
•
•
•
•
•
Publication
26460546 | J:269471
 
First Author: Yzaguirre AD
Year: 2015
Journal: Elife
Title: Loss of neurofibromin Ras-GAP activity enhances the formation of cardiac blood islands in murine embryos.
Volume: 4
Pages: e07780
•
•
•
•
•
Publication
24913553 | J:217840
First Author: Malone CF
Year: 2014
Journal: Cancer Discov
Title: Defining key signaling nodes and therapeutic biomarkers in NF1-mutant cancers.
Volume: 4
Issue: 9
Pages: 1062-73
•
•
•
•
•
Publication
31431463 | J:279985
First Author: Ohka F
Year: 2019
Journal: Cancer Res
Title: Pathogenic Epigenetic Consequences of Genetic Alterations in IDH-Wild-Type Diffuse Astrocytic Gliomas.
Volume: 79
Issue: 19
Pages: 4814-4827
•
•
•
•
•
Publication
21467166 | J:171978
First Author: Yang A
Year: 2011
Journal: Cancer Res
Title: Increased survival following tumorigenesis in Ts65Dn mice that model Down syndrome.
Volume: 71
Issue: 10
Pages: 3573-81
•
•
•
•
•
Publication
29392777 | J:258723
First Author: Gonzalez PP
Year: 2018
Journal: Glia
Title: p53 and NF 1 loss plays distinct but complementary roles in glioma initiation and progression.
Volume: 66
Issue: 5
Pages: 999-1015
•
•
•
•
•
Publication
11793011 | J:74257
First Author: Costa RM
Year: 2002
Journal: Nature
Title: Mechanism for the learning deficits in a mouse model of neurofibromatosis type 1.
Volume: 415
Issue: 6871
Pages: 526-30
•
•
•
•
•
Publication
19846776 | J:154673
First Author: Gregorian C
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: PTEN dosage is essential for neurofibroma development and malignant transformation.
Volume: 106
Issue: 46
Pages: 19479-84
•
•
•
•
•
Publication
16644864 | J:109530
First Author: Li F
Year: 2006
Journal: Hum Mol Genet
Title: Neurofibromin is a novel regulator of RAS-induced signals in primary vascular smooth muscle cells.
Volume: 15
Issue: 11
Pages: 1921-30
•
•
•
•
•
Publication
26740548 | J:229474
First Author: Bessler WK
Year: 2016
Journal: Hum Mol Genet
Title: Nf1+/- monocytes/macrophages induce neointima formation via CCR2 activation.
Volume: 25
Issue: 6
Pages: 1129-39
•
•
•
•
•
Publication
23221339 | J:194159
First Author: Staser K
Year: 2013
Journal: J Clin Invest
Title: Normal hematopoiesis and neurofibromin-deficient myeloproliferative disease require Erk.
Volume: 123
Issue: 1
Pages: 329-34
•
•
•
•
•
Publication
15133494 | J:91460
First Author: Shollar D
Year: 2004
Journal: Oncogene
Title: JCV T-antigen interacts with the neurofibromatosis type 2 gene product in a transgenic mouse model of malignant peripheral nerve sheath tumors.
Volume: 23
Issue: 32
Pages: 5459-67
•
•
•
•
•
Publication
18164202 | J:144615
First Author: Johannessen CM
Year: 2008
Journal: Curr Biol
Title: TORC1 is essential for NF1-associated malignancies.
Volume: 18
Issue: 1
Pages: 56-62
•
•
•
•
•
Publication
17348023 | J:156097
First Author: Su W
Year: 2007
Journal: Glia
Title: Mice with GFAP-targeted loss of neurofibromin demonstrate increased axonal MET expression with aging.
Volume: 55
Issue: 7
Pages: 723-33
•
•
•
•
•
Publication
17053831 | J:114609
First Author: Yang FC
Year: 2006
Journal: J Clin Invest
Title: Hyperactivation of p21ras and PI3K cooperate to alter murine and human neurofibromatosis type 1-haploinsufficient osteoclast functions.
Volume: 116
Issue: 11
Pages: 2880-91
•
•
•
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