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Search results 201 to 300 out of 424 for Npc1

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Category: Publication
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Type Details Score
Publication
12528192 | J:81305
First Author: Sarna JR
Year: 2003
Journal: J Comp Neurol
Title: Patterned Purkinje cell degeneration in mouse models of Niemann-Pick type C disease.
Volume: 456
Issue: 3
Pages: 279-91
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Publication
6315811 | J:7245
First Author: Miyawaki S
Year: 1983
Journal: J Hered
Title: Time course of hepatic lipids accumulation in a strain of mice with an inherited deficiency of sphingomyelinase.
Volume: 74
Issue: 6
Pages: 465-8
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Publication
- | J:685
First Author: Tokoro T
Year: 1991
Journal: Am J Hum Genet
Title: Impaired exogenous cholesterol esterification in Niemann-Pick mouse
Volume: 49
Issue: 4 Suppl
Pages: 107 (Abstr.)
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Publication
11504598 | J:102782
First Author: Yamada A
Year: 2001
Journal: Brain Dev
Title: Progressive neuronal loss in the ventral posterior lateral and medial nuclei of thalamus in Niemann-Pick disease type C mouse brain.
Volume: 23
Issue: 5
Pages: 288-97
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Publication
3559164 | J:8630
First Author: Miyawaki S
Year: 1986
Journal: J Hered
Title: A mouse model for Niemann-Pick disease. Influence of genetic background on disease expression in spm/spm mice.
Volume: 77
Issue: 6
Pages: 379-84
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Publication
9107683 | J:39614
First Author: Erickson RP
Year: 1997
Journal: Mamm Genome
Title: High-resolution mapping of the spm (Niemann-Pick Type C) locus on mouse chromosome 18.
Volume: 8
Issue: 5
Pages: 355-6
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Publication
- | J:36039
 
First Author: Tokoro T
Year: 1996
Journal: Jikeikai Med J
Title: Allelic mutations in two Niemann-Pick disease model mice: SPM (C57BL/KSJ) and NCTR (NCTR-BALB/C).
Volume: 43
Pages: 115-21
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Publication
22216111 | J:182335
First Author: Vázquez MC
Year: 2011
Journal: PLoS One
Title: Alteration of gene expression profile in Niemann-Pick type C mice correlates with tissue damage and oxidative stress.
Volume: 6
Issue: 12
Pages: e28777
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Publication
10770933 | J:110802
First Author: Henderson LP
Year: 2000
Journal: J Biol Chem
Title: Embryonic striatal neurons from niemann-pick type C mice exhibit defects in cholesterol metabolism and neurotrophin responsiveness.
Volume: 275
Issue: 26
Pages: 20179-87
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Publication
32472585 | J:298746
First Author: Houben T
Year: 2020
Journal: J Pathol
Title: Sex-opposed inflammatory effects of 27-hydroxycholesterol are mediated via differences in estrogen signaling.
Volume: 251
Issue: 4
Pages: 429-439
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Publication
3949747 | J:8198
First Author: Pentchev PG
Year: 1986
Journal: J Biol Chem
Title: The cholesterol storage disorder of the mutant BALB/c mouse. A primary genetic lesion closely linked to defective esterification of exogenously derived cholesterol and its relationship to human type C Niemann-Pick disease.
Volume: 261
Issue: 6
Pages: 2772-7
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Publication
21459030 | J:172067
First Author: Muralidhar A
Year: 2011
Journal: Mol Genet Metab
Title: Pulmonary function and pathology in hydroxypropyl-beta-cyclodextin-treated and untreated Npc1⁻/⁻ mice.
Volume: 103
Issue: 2
Pages: 142-7
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Publication
33878344 | J:307174
First Author: Roney JC
Year: 2021
Journal: Dev Cell
Title: Lipid-mediated motor-adaptor sequestration impairs axonal lysosome delivery leading to autophagic stress and dystrophy in Niemann-Pick type C.
Volume: 56
Issue: 10
Pages: 1452-1468.e8
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Publication
25522247 | J:223979
First Author: Soga M
Year: 2015
Journal: Stem Cells
Title: HPGCD outperforms HPBCD as a potential treatment for Niemann-Pick disease type C during disease modeling with iPS cells.
Volume: 33
Issue: 4
Pages: 1075-88
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Publication
12692847 | J:149812
First Author: Treiber-Held S
Year: 2003
Journal: J Pathol
Title: Spatial and temporal distribution of intracellular free cholesterol in brains of a Niemann-Pick type C mouse model showing hyperphosphorylated tau protein. Implications for Alzheimer's disease.
Volume: 200
Issue: 1
Pages: 95-103
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Publication
22892156 | J:190568
First Author: Taylor AM
Year: 2012
Journal: J Lipid Res
Title: Cyclodextrin mediates rapid changes in lipid balance in Npc1-/- mice without carrying cholesterol through the bloodstream.
Volume: 53
Issue: 11
Pages: 2331-42
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Publication
15639190 | J:95531
First Author: Wu YP
Year: 2005
Journal: Mol Genet Metab
Title: Apoptosis accompanied by up-regulation of TNF-alpha death pathway genes in the brain of Niemann-Pick type C disease.
Volume: 84
Issue: 1
Pages: 9-17
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Publication
31847086 | J:290797
 
First Author: Rabenstein M
Year: 2019
Journal: Int J Mol Sci
Title: Alteration of GABAergic Input Precedes Neurodegeneration of Cerebellar Purkinje Cells of NPC1-Deficient Mice.
Volume: 20
Issue: 24
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Publication
31067492 | J:282559
 
First Author: Shin SD
Year: 2019
Journal: Neurosci Lett
Title: Interferon downstream signaling is activated early in pre-symptomatic Niemann-Pick disease type C.
Volume: 706
Pages: 43-50
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Publication
15331409 | J:92985
First Author: Zhang M
Year: 2004
Journal: Am J Pathol
Title: Cyclin-dependent kinase inhibitors attenuate protein hyperphosphorylation, cytoskeletal lesion formation, and motor defects in Niemann-Pick Type C mice.
Volume: 165
Issue: 3
Pages: 843-53
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Publication
8382896 | J:4992
First Author: Higashi Y
Year: 1993
Journal: Acta Neuropathol
Title: Cerebellar degeneration in the Niemann-Pick type C mouse.
Volume: 85
Issue: 2
Pages: 175-84
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Publication
24391715 | J:209834
First Author: Hovakimyan M
Year: 2013
Journal: PLoS One
Title: Olfactory deficits in Niemann-Pick type C1 (NPC1) disease.
Volume: 8
Issue: 12
Pages: e82216
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Publication
15144855 | J:94570
First Author: Ohara S
Year: 2004
Journal: Exp Neurol
Title: Axonal dystrophy of dorsal root ganglion sensory neurons in a mouse model of Niemann-Pick disease type C.
Volume: 187
Issue: 2
Pages: 289-98
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Publication
15943586 | J:117577
First Author: Vainio S
Year: 2005
Journal: Biochem J
Title: Defective insulin receptor activation and altered lipid rafts in Niemann-Pick type C disease hepatocytes.
Volume: 391
Issue: Pt 3
Pages: 465-72
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Publication
15105438 | J:91430
First Author: Gévry NY
Year: 2004
Journal: Mol Endocrinol
Title: Aberrant intracellular cholesterol transport disrupts pituitary and ovarian function.
Volume: 18
Issue: 7
Pages: 1778-86
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Publication
9950794 | J:76733
First Author: Xie C
Year: 1999
Journal: Am J Physiol
Title: Cholesterol balance and metabolism in mice with loss of function of Niemann-Pick C protein.
Volume: 276
Issue: 2 Pt 1
Pages: E336-44
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Publication
6325448 | J:76734
First Author: Pentchev PG
Year: 1984
Journal: J Biol Chem
Title: A genetic storage disorder in BALB/C mice with a metabolic block in esterification of exogenous cholesterol.
Volume: 259
Issue: 9
Pages: 5784-91
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Publication
12437586 | J:80447
First Author: Karten B
Year: 2002
Journal: J Neurochem
Title: Cholesterol accumulates in cell bodies, but is decreased in distal axons, of Niemann-Pick C1-deficient neurons.
Volume: 83
Issue: 5
Pages: 1154-63
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Publication
7484091 | J:28629
First Author: Higashi Y
Year: 1995
Journal: Acta Neuropathol
Title: Peripheral nerve pathology in Niemann-Pick type C mouse.
Volume: 90
Issue: 2
Pages: 158-63
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Publication
15835268 | J:104844
First Author: Li H
Year: 2005
Journal: J Neuropathol Exp Neurol
Title: Molecular, anatomical, and biochemical events associated with neurodegeneration in mice with Niemann-Pick type C disease.
Volume: 64
Issue: 4
Pages: 323-33
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Publication
11823057 | J:126856
First Author: German DC
Year: 2002
Journal: Neuroscience
Title: Neurodegeneration in the Niemann-Pick C mouse: glial involvement.
Volume: 109
Issue: 3
Pages: 437-50
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Publication
6765732 | J:10213
First Author: Shio H
Year: 1982
Journal: Am J Pathol
Title: Lysosome lipid storage disorder in NCTR-BALB/c mice. II. Morphologic and cytochemical studies.
Volume: 108
Issue: 2
Pages: 150-9
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Publication
6101077 | J:10214
First Author: Bhuvaneswaran C
Year: 1982
Journal: Am J Pathol
Title: Lysosome lipid storage disorder in NCTR-BALB/c mice. III. Isolation and analysis of storage inclusions from liver.
Volume: 108
Issue: 2
Pages: 160-70
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Publication
12530642 | J:91497
First Author: Gévry NY
Year: 2002
Journal: Endocr Res
Title: The role and regulation of the Niemann-Pick C1 gene in adrenal steroidogenesis.
Volume: 28
Issue: 4
Pages: 403-12
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Publication
20883783 | J:167246
First Author: Klein A
Year: 2011
Journal: Neurobiol Dis
Title: Oxidative stress activates the c-Abl/p73 proapoptotic pathway in Niemann-Pick type C neurons.
Volume: 41
Issue: 1
Pages: 209-18
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Publication
9422368 | J:120242
First Author: Suresh S
Year: 1998
Journal: J Neurochem
Title: Cellular cholesterol storage in the Niemann-Pick disease type C mouse is associated with increased expression and defective processing of apolipoprotein D.
Volume: 70
Issue: 1
Pages: 242-51
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Publication
34489968 | J:335350
 
First Author: Houben T
Year: 2021
Journal: Front Immunol
Title: Pro-Inflammatory Implications of 2-Hydroxypropyl-β-cyclodextrin Treatment.
Volume: 12
Pages: 716357
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Publication
9675302 | J:48956
First Author: Yadid G
Year: 1998
Journal: Brain Res
Title: Neurochemical alterations in the cerebellum of a murine model of Niemann-Pick type C disease.
Volume: 799
Issue: 2
Pages: 250-6
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Publication
9260750 | J:42120
First Author: Goodrum JF
Year: 1997
Journal: J Neurosci Res
Title: Cholesterol reutilization during myelination of regenerating PNS axons is impaired in Niemann-Pick disease type C mice.
Volume: 49
Issue: 3
Pages: 389-92
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Publication
36116252 | J:329991
 
First Author: Yamada Y
Year: 2022
Journal: Biomed Pharmacother
Title: Fine-tuned cholesterol solubilizer, mono-6-O-α-D-maltosyl-γ-cyclodextrin, ameliorates experimental Niemann-Pick disease type C without hearing loss.
Volume: 155
Pages: 113698
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Publication
19328188 | J:156575
 
First Author: Liao G
Year: 2009
Journal: Brain Res
Title: Allopregnanolone treatment delays cholesterol accumulation and reduces autophagic/lysosomal dysfunction and inflammation in Npc1-/- mouse brain.
Volume: 1270
Pages: 140-51
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Publication
22776200 | J:186234
First Author: Ong QR
Year: 2012
Journal: Biochem Biophys Res Commun
Title: Impaired insulin signaling in an animal model of Niemann-Pick Type C disease.
Volume: 424
Issue: 3
Pages: 482-7
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Publication
17170046 | J:140844
First Author: Wasser CR
Year: 2007
Journal: J Physiol
Title: Cholesterol-dependent balance between evoked and spontaneous synaptic vesicle recycling.
Volume: 579
Issue: Pt 2
Pages: 413-29
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Publication
15217094 | J:104958
First Author: Takikita S
Year: 2004
Journal: J Neuropathol Exp Neurol
Title: Perturbed myelination process of premyelinating oligodendrocyte in Niemann-Pick type C mouse.
Volume: 63
Issue: 6
Pages: 660-73
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Publication
23846690 | J:203447
First Author: Bosch B
Year: 2013
Journal: J Biol Chem
Title: Disruption of multivesicular body vesicles does not affect major histocompatibility complex (MHC) class II-peptide complex formation and antigen presentation by dendritic cells.
Volume: 288
Issue: 34
Pages: 24286-92
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Publication
- | J:83825
 
First Author: Boothe AD
Year: 1977
Journal: Fed Proc
Title: Tissue cholesterol storage disorder in BALB/c mice: histologic findings
Volume: 36
Pages: 1158 (Abstr.)
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Publication
- | J:83826
 
First Author: Morris MD
Year: 1977
Journal: Fed Proc
Title: Tissue cholesterol storage disorder in BALB/c mice
Volume: 36
Pages: 1158 (Abstr.)
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Publication
4031853 | J:7989
First Author: Weintraub H
Year: 1985
Journal: J Neurochem
Title: Neurological mutation characterized by dysmyelination in NCTR-Balb/C mouse with lysosomal lipid storage disease.
Volume: 45
Issue: 3
Pages: 665-72
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3827919 | J:8620
First Author: Patel SC
Year: 1987
Journal: Biochem Biophys Res Commun
Title: Impaired cholesterol esterification in primary brain cultures of the lysosomal cholesterol storage disorder (LCSD) mouse mutant.
Volume: 143
Issue: 1
Pages: 233-40
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Publication
15208706 | J:91682
First Author: Griffin LD
Year: 2004
Journal: Nat Med
Title: Niemann-Pick type C disease involves disrupted neurosteroidogenesis and responds to allopregnanolone.
Volume: 10
Issue: 7
Pages: 704-11
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Publication
8312368 | J:83835
First Author: Pentchev PG
Year: 1994
Journal: Biochim Biophys Acta
Title: The Niemann-Pick C lesion and its relationship to the intracellular distribution and utilization of LDL cholesterol.
Volume: 1225
Issue: 3
Pages: 235-43
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Publication
36455410 | J:351530
 
First Author: Gray J
Year: 2022
Journal: EBioMedicine
Title: Heat shock protein amplification improves cerebellar myelination in the Npc1(nih) mouse model.
Volume: 86
Pages: 104374
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8900297 | J:36923
First Author: Veyron P
Year: 1996
Journal: Transplantation
Title: Transplantation of fetal liver cells corrects accumulation of lipids in tissues and prevents fatal neuropathy in cholesterol-storage disease BALB/c mice.
Volume: 62
Issue: 8
Pages: 1039-45
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Publication
12151531 | J:78091
First Author: Bu B
Year: 2002
Journal: J Neurosci
Title: Deregulation of cdk5, hyperphosphorylation, and cytoskeletal pathology in the Niemann-Pick type C murine model.
Volume: 22
Issue: 15
Pages: 6515-25
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Publication
38142760 | J:349265
First Author: Nunes MJ
Year: 2024
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Cholesterol redistribution triggered by CYP46A1 gene therapy improves major hallmarks of Niemann-Pick type C disease but is not sufficient to halt neurodegeneration.
Volume: 1870
Issue: 3
Pages: 166993
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Publication
1500436 | J:1093
 
First Author: Weintraub H
Year: 1992
Journal: J Cell Sci
Title: Morphometric studies of pancreatic acinar granule formation in NCTR-Balb/c mice.
Volume: 102 ( Pt 1)
Pages: 141-7
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Publication
8446622 | J:4347
First Author: Carstea ED
Year: 1993
Journal: Proc Natl Acad Sci U S A
Title: Linkage of Niemann-Pick disease type C to human chromosome 18.
Volume: 90
Issue: 5
Pages: 2002-4
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8370582 | J:15378
First Author: Kurimasa A
Year: 1993
Journal: Hum Genet
Title: Restoration of the cholesterol metabolism in 3T3 cell lines derived from the sphingomyelinosis mouse (spm/spm) by transfer of a human chromosome 18.
Volume: 92
Issue: 2
Pages: 157-62
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Publication
9207099 | J:41745
First Author: Gu JZ
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Substantial narrowing of the Niemann-Pick C candidate interval by yeast artificial chromosome complementation.
Volume: 94
Issue: 14
Pages: 7378-83
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9795206 | J:51136
First Author: Schedin S
Year: 1998
Journal: Biochim Biophys Acta
Title: Alterations in the biosynthesis of cholesterol, dolichol and dolichyl-P in the genetic cholesterol homeostasis disorder, Niemann-Pick type C disease.
Volume: 1394
Issue: 2-3
Pages: 177-86
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Publication
32144204 | J:286824
First Author: Akiyama H
Year: 2020
Journal: J Biol Chem
Title: Glucocerebrosidases catalyze a transgalactosylation reaction that yields a newly-identified brain sterol metabolite, galactosylated cholesterol.
Volume: 295
Issue: 16
Pages: 5257-5277
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Publication
12711538 | J:83325
First Author: Irla M
Year: 2003
Journal: Gene Expr Patterns
Title: Spatial, a new nuclear factor tightly regulated during mouse spermatogenesis.
Volume: 3
Issue: 2
Pages: 135-8
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Publication
25417698 | J:281260
 
First Author: Lee H
Year: 2014
Journal: Nat Commun
Title: Pathological roles of the VEGF/SphK pathway in Niemann-Pick type C neurons.
Volume: 5
Pages: 5514
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Publication
22493001 | J:184610
First Author: Lopez ME
Year: 2012
Journal: Hum Mol Genet
Title: Neuronal and epithelial cell rescue resolves chronic systemic inflammation in the lipid storage disorder Niemann-Pick C.
Volume: 21
Issue: 13
Pages: 2946-60
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Publication
24599001 | J:309876
First Author: Lee H
Year: 2014
Journal: Mol Cells
Title: Inhibition of GM3 synthase attenuates neuropathology of Niemann-Pick disease Type C. by affecting sphingolipid metabolism.
Volume: 37
Issue: 2
Pages: 161-71
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Publication
26275242 | J:242773
First Author: Marques AR
Year: 2015
Journal: PLoS One
Title: Reducing GBA2 Activity Ameliorates Neuropathology in Niemann-Pick Type C Mice.
Volume: 10
Issue: 8
Pages: e0135889
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Publication
34175669 | J:312484
 
First Author: Torres S
Year: 2021
Journal: Redox Biol
Title: Acid ceramidase improves mitochondrial function and oxidative stress in Niemann-Pick type C disease by repressing STARD1 expression and mitochondrial cholesterol accumulation.
Volume: 45
Pages: 102052
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Publication
6765731 | J:10212
First Author: Morris MD
Year: 1982
Journal: Am J Pathol
Title: Lysosome lipid storage disorder in NCTR-BALB/c mice. I. Description of the disease and genetics.
Volume: 108
Issue: 2
Pages: 140-9
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Publication
35024626 | J:353179
First Author: Goicoechea L
Year: 2022
Journal: STAR Protoc
Title: GST-Perfringolysin O production for the localization and quantification of membrane cholesterol in human and mouse brain and liver.
Volume: 3
Issue: 1
Pages: 101068
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Publication
27152617 | J:232553
First Author: Chung C
Year: 2016
Journal: PLoS Genet
Title: Heat Shock Protein Beta-1 Modifies Anterior to Posterior Purkinje Cell Vulnerability in a Mouse Model of Niemann-Pick Type C Disease.
Volume: 12
Issue: 5
Pages: e1006042
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Publication
10518564 | J:76735
First Author: Xie C
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Cholesterol accumulation in tissues of the Niemann-pick type C mouse is determined by the rate of lipoprotein-cholesterol uptake through the coated-pit pathway in each organ.
Volume: 96
Issue: 21
Pages: 11992-7
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Publication
10946016 | J:64028
First Author: Xie C
Year: 2000
Journal: J Lipid Res
Title: Centripetal cholesterol flow from the extrahepatic organs through the liver is normal in mice with mutated Niemann-Pick type C protein (NPC1).
Volume: 41
Issue: 8
Pages: 1278-89
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Publication
11530237 | J:126474
First Author: German DC
Year: 2001
Journal: Neuroscience
Title: Degeneration of neurons and glia in the Niemann-Pick C mouse is unrelated to the low-density lipoprotein receptor.
Volume: 105
Issue: 4
Pages: 999-1005
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Publication
15790756 | J:100351
First Author: Erickson RP
Year: 2005
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Liver disease with altered bile acid transport in Niemann-Pick C mice on a high-fat, 1% cholesterol diet.
Volume: 289
Issue: 2
Pages: G300-7
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Publication
26467605 | J:237590
 
First Author: Richardson K
Year: 2016
Journal: Behav Brain Res
Title: Circadian profiling in two mouse models of lysosomal storage disorders; Niemann Pick type-C and Sandhoff disease.
Volume: 297
Pages: 213-23
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Publication
16525053 | J:106228
First Author: Hallows JL
Year: 2006
Journal: J Neurosci
Title: p35/p25 is not essential for tau and cytoskeletal pathology or neuronal loss in Niemann-Pick type C disease.
Volume: 26
Issue: 10
Pages: 2738-44
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Publication
19151629 | J:263237
First Author: Micsenyi MC
Year: 2009
Journal: J Neuropathol Exp Neurol
Title: Neuropathology of the Mcoln1(-/-) knockout mouse model of mucolipidosis type IV.
Volume: 68
Issue: 2
Pages: 125-35
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Publication
26682800 | J:237650
First Author: Park S
Year: 2016
Journal: EMBO Rep
Title: Fusion of lysosomes with secretory organelles leads to uncontrolled exocytosis in the lysosomal storage disease mucolipidosis type IV.
Volume: 17
Issue: 2
Pages: 266-78
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Publication
22223354 | J:192698
First Author: Hölttä-Vuori M
Year: 2012
Journal: Circ Res
Title: Endosomal actin remodeling by coronin-1A controls lipoprotein uptake and degradation in macrophages.
Volume: 110
Issue: 3
Pages: 450-5
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Publication
21303697 | J:172769
First Author: Nunes A
Year: 2011
Journal: Neurobiol Dis
Title: Loss of amyloid precursor protein in a mouse model of Niemann-Pick type C disease exacerbates its phenotype and disrupts tau homeostasis.
Volume: 42
Issue: 3
Pages: 349-59
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Publication
16374838 | J:115647
First Author: Klein A
Year: 2006
Journal: Hepatology
Title: NPC2 is expressed in human and murine liver and secreted into bile: potential implications for body cholesterol homeostasis.
Volume: 43
Issue: 1
Pages: 126-33
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Publication
36379959 | J:346915
First Author: Tu X
Year: 2022
Journal: Nat Commun
Title: Interruption of post-Golgi STING trafficking activates tonic interferon signaling.
Volume: 13
Issue: 1
Pages: 6977
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Publication
7670466 | J:26732
First Author: Horinouchi K
Year: 1995
Journal: Nat Genet
Title: Acid sphingomyelinase deficient mice: a model of types A and B Niemann-Pick disease.
Volume: 10
Issue: 3
Pages: 288-93
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Publication
9565090 | J:47004
First Author: Miranda SR
Year: 1998
Journal: Transplantation
Title: Biochemical, pathological, and clinical response to transplantation of normal bone marrow cells into acid sphingomyelinase-deficient mice.
Volume: 65
Issue: 7
Pages: 884-92
•
•
•
•
•
Publication
7600574 | J:26748
First Author: Otterbach B
Year: 1995
Journal: Cell
Title: Acid sphingomyelinase-deficient mice mimic the neurovisceral form of human lysosomal storage disease (Niemann-Pick disease).
Volume: 81
Issue: 7
Pages: 1053-61
•
•
•
•
•
Publication
10608504 | J:59785
First Author: Kolodny EH
Year: 2000
Journal: Curr Opin Hematol
Title: Niemann-Pick disease.
Volume: 7
Issue: 1
Pages: 48-52
•
•
•
•
•
Publication
8288255 | J:15622
First Author: Horinouchi K
Year: 1993
Journal: Genomics
Title: Mouse models of Niemann-Pick disease: mutation analysis and chromosomal mapping rule out the type A and B forms.
Volume: 18
Issue: 2
Pages: 450-1
•
•
•
•
•
Publication
8181053 | J:18031
First Author: Kolesnick R
Year: 1994
Journal: Cell
Title: The sphingomyelin pathway in tumor necrosis factor and interleukin-1 signaling.
Volume: 77
Issue: 3
Pages: 325-8
•
•
•
•
•
Publication
12711537 | J:83326
First Author: Jadrich JL
Year: 2003
Journal: Gene Expr Patterns
Title: Expression of TAK1, a mediator of TGF-beta and BMP signaling, during mouse embryonic development.
Volume: 3
Issue: 2
Pages: 131-4
•
•
•
•
•
Publication
- | J:87349
     
First Author: JAX Neuroscience Mutagenesis Facility
Year: 2004
Journal: MGI Direct Data Submission
Title: Heritable mouse mutants from JAX NMF ENU Mutagenesis Program
•
•
•
•
•
Publication
26724485 | J:231478
First Author: Marques AR
Year: 2016
Journal: J Lipid Res
Title: Glucosylated cholesterol in mammalian cells and tissues: formation and degradation by multiple cellular β-glucosidases.
Volume: 57
Issue: 3
Pages: 451-63
•
•
•
•
•
Publication
16950136 | J:129725
First Author: Marí M
Year: 2006
Journal: Cell Metab
Title: Mitochondrial free cholesterol loading sensitizes to TNF- and Fas-mediated steatohepatitis.
Volume: 4
Issue: 3
Pages: 185-98
•
•
•
•
•
Publication
27605553 | J:259551
First Author: Kirkegaard T
Year: 2016
Journal: Sci Transl Med
Title: Heat shock protein-based therapy as a potential candidate for treating the sphingolipidoses.
Volume: 8
Issue: 355
Pages: 355ra118
•
•
•
•
•
Publication
31086348 | J:289192
First Author: Yousef H
Year: 2019
Journal: Nat Med
Title: Aged blood impairs hippocampal neural precursor activity and activates microglia via brain endothelial cell VCAM1.
Volume: 25
Issue: 6
Pages: 988-1000
•
•
•
•
•
Publication
29058287 | J:310938
First Author: Ba L
Year: 2017
Journal: J Huazhong Univ Sci Technolog Med Sci
Title: Aberrant activation of Cdc2/cyclin B1 is involved in initiation of cytoskeletal pathology in murine Niemann-Pick disease type C.
Volume: 37
Issue: 5
Pages: 732-739
•
•
•
•
•
Publication
30775969 | J:271336
   
First Author: Yambire KF
Year: 2019
Journal: Elife
Title: Mitochondrial biogenesis is transcriptionally repressed in lysosomal lipid storage diseases.
Volume: 8
•
•
•
•
•
Publication
26950892 | J:236650
First Author: Li X
Year: 2016
Journal: Nat Cell Biol
Title: A molecular mechanism to regulate lysosome motility for lysosome positioning and tubulation.
Volume: 18
Issue: 4
Pages: 404-17
•
•
•
•
•
Publication
15078881 | J:91039
First Author: te Vruchte D
Year: 2004
Journal: J Biol Chem
Title: Accumulation of glycosphingolipids in Niemann-Pick C disease disrupts endosomal transport.
Volume: 279
Issue: 25
Pages: 26167-75
•
•
•
•
•
Publication
27565738 | J:255892
First Author: Yáñez MJ
Year: 2016
Journal: Biochim Biophys Acta
Title: c-Abl links APP-BACE1 interaction promoting APP amyloidogenic processing in Niemann-Pick type C disease.
Volume: 1862
Issue: 11
Pages: 2158-2167
•
•
•
•
•
Publication
1679325 | J:3259
First Author: Sakai Y
Year: 1991
Journal: Biochem Genet
Title: A molecular genetic linkage map of mouse chromosome 18, including spm, Grl-1, Fim-2/c-fms, and Mbp.
Volume: 29
Issue: 1-2
Pages: 103-13
•
•
•
•
•




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