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Search results 201 to 300 out of 1487 for Ptch1

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Category: Publication
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Type Details Score
Publication
24631180 | J:208129
First Author: Xu J
Year: 2014
Journal: Am J Pathol
Title: Hair follicle disruption facilitates pathogenesis to UVB-induced cutaneous inflammation and basal cell carcinoma development in Ptch(+/-) mice.
Volume: 184
Issue: 5
Pages: 1529-40
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Publication
24769368 | J:214670
First Author: Okolowsky N
Year: 2014
Journal: Dev Biol
Title: Oestrogen receptor-alpha regulates non-canonical Hedgehog-signalling in the mammary gland.
Volume: 391
Issue: 2
Pages: 219-29
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Publication
20018657 | J:156471
First Author: Ohazama A
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: A role for suppressed incisor cuspal morphogenesis in the evolution of mammalian heterodont dentition.
Volume: 107
Issue: 1
Pages: 92-7
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Publication
16968775 | J:113717
First Author: Trowbridge JJ
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Hedgehog modulates cell cycle regulators in stem cells to control hematopoietic regeneration.
Volume: 103
Issue: 38
Pages: 14134-9
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Publication
24092238 | J:205413
First Author: Dey J
Year: 2013
Journal: Cancer Res
Title: MyoD is a tumor suppressor gene in medulloblastoma.
Volume: 73
Issue: 22
Pages: 6828-37
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Publication
27181404 | J:234016
First Author: Ho Y
Year: 2016
Journal: Am J Pathol
Title: PERK Activation Promotes Medulloblastoma Tumorigenesis by Attenuating Premalignant Granule Cell Precursor Apoptosis.
Volume: 186
Issue: 7
Pages: 1939-51
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Publication
30695697 | J:272576
First Author: Chang CH
Year: 2019
Journal: Dev Cell
Title: Atoh1 Controls Primary Cilia Formation to Allow for SHH-Triggered Granule Neuron Progenitor Proliferation.
Volume: 48
Issue: 2
Pages: 184-199.e5
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Publication
32579914 | J:304690
First Author: Cheng Y
Year: 2020
Journal: Cell Rep
Title: NeuroD1 Dictates Tumor Cell Differentiation in Medulloblastoma.
Volume: 31
Issue: 12
Pages: 107782
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Publication
35680976 | J:325596
First Author: Pokrajac NT
Year: 2022
Journal: Commun Biol
Title: Three dimensional reconstruction of the mouse cerebellum in Hedgehog-driven medulloblastoma models to identify Norrin-dependent effects on preneoplasia.
Volume: 5
Issue: 1
Pages: 569
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Publication
14568546 | J:86153
First Author: Kim JY
Year: 2003
Journal: Dev Biol
Title: Medulloblastoma tumorigenesis diverges from cerebellar granule cell differentiation in patched heterozygous mice.
Volume: 263
Issue: 1
Pages: 50-66
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Publication
26834157 | J:232626
First Author: Klein C
Year: 2016
Journal: J Exp Med
Title: Ptch2 loss drives myeloproliferation and myeloproliferative neoplasm progression.
Volume: 213
Issue: 2
Pages: 273-90
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Publication
18974121 | J:140638
First Author: Corcoran RB
Year: 2008
Journal: Cancer Res
Title: Insulin-like growth factor 2 is required for progression to advanced medulloblastoma in patched1 heterozygous mice.
Volume: 68
Issue: 21
Pages: 8788-95
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Publication
18688029 | J:139587
First Author: Gu LH
Year: 2008
Journal: Am J Pathol
Title: Hedgehog signaling, keratin 6 induction, and sebaceous gland morphogenesis: implications for pachyonychia congenita and related conditions.
Volume: 173
Issue: 3
Pages: 752-61
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Publication
32376680 | J:294192
 
First Author: Ma P
Year: 2020
Journal: Development
Title: RNF220 is required for cerebellum development and regulates medulloblastoma progression through epigenetic modulation of Shh signaling.
Volume: 147
Issue: 21
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Publication
18036580 | J:293341
First Author: Lelievre V
Year: 2008
Journal: Dev Biol
Title: Disruption of the PACAP gene promotes medulloblastoma in ptc1 mutant mice.
Volume: 313
Issue: 1
Pages: 359-70
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Publication
30340023 | J:269133
First Author: Raleigh DR
Year: 2018
Journal: Mol Cell
Title: Cilia-Associated Oxysterols Activate Smoothened.
Volume: 72
Issue: 2
Pages: 316-327.e5
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Publication
29894688 | J:262547
First Author: Zhu D
Year: 2018
Journal: Cancer Cell
Title: BAI1 Suppresses Medulloblastoma Formation by Protecting p53 from Mdm2-Mediated Degradation.
Volume: 33
Issue: 6
Pages: 1004-1016.e5
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Publication
25816987 | J:239288
First Author: Eisner A
Year: 2015
Journal: Dev Cell
Title: The Eya1 phosphatase promotes Shh signaling during hindbrain development and oncogenesis.
Volume: 33
Issue: 1
Pages: 22-35
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Publication
23389290 | J:198323
First Author: Barakat MT
Year: 2013
Journal: Carcinogenesis
Title: Kif3a is necessary for initiation and maintenance of medulloblastoma.
Volume: 34
Issue: 6
Pages: 1382-92
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Publication
29202464 | J:258389
First Author: Raleigh DR
Year: 2018
Journal: J Clin Invest
Title: Hedgehog signaling drives medulloblastoma growth via CDK6.
Volume: 128
Issue: 1
Pages: 120-124
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Publication
20516124 | J:161624
First Author: Ayrault O
Year: 2010
Journal: Cancer Res
Title: Atoh1 inhibits neuronal differentiation and collaborates with Gli1 to generate medulloblastoma-initiating cells.
Volume: 70
Issue: 13
Pages: 5618-27
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Publication
19171780 | J:143859
First Author: Kessler JD
Year: 2009
Journal: Genes Dev
Title: N-myc alters the fate of preneoplastic cells in a mouse model of medulloblastoma.
Volume: 23
Issue: 2
Pages: 157-70
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Publication
17893326 | J:129050
First Author: Yun JS
Year: 2007
Journal: Mol Cell Biol
Title: A novel role of the Mad family member Mad3 in cerebellar granule neuron precursor proliferation.
Volume: 27
Issue: 23
Pages: 8178-89
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Publication
38834071 | J:350996
     
First Author: Shiraishi R
Year: 2024
Journal: Dev Cell
Title: Cancer-specific epigenome identifies oncogenic hijacking by nuclear factor I family proteins for medulloblastoma progression.
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Publication
11673255 | J:108687
First Author: Pierucci-Alves F
Year: 2001
Journal: Biol Reprod
Title: A developmental study of the Desert hedgehog-null mouse testis.
Volume: 65
Issue: 5
Pages: 1392-402
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Publication
10686522 | J:102987
First Author: Jacobson L
Year: 2000
Journal: Neuroendocrinology
Title: CRH deficiency impairs but does not block pituitary-adrenal responses to diverse stressors.
Volume: 71
Issue: 2
Pages: 79-87
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Publication
23115191 | J:192289
First Author: Farioli-Vecchioli S
Year: 2012
Journal: J Neurosci
Title: Tis21 knock-out enhances the frequency of medulloblastoma in Patched1 heterozygous mice by inhibiting the Cxcl3-dependent migration of cerebellar neurons.
Volume: 32
Issue: 44
Pages: 15547-64
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Publication
18660545 | J:139958
First Author: Tanori M
Year: 2008
Journal: Carcinogenesis
Title: PARP-1 cooperates with Ptc1 to suppress medulloblastoma and basal cell carcinoma.
Volume: 29
Issue: 10
Pages: 1911-9
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Publication
25476449 | J:217807
First Author: Infante P
Year: 2015
Journal: EMBO J
Title: Gli1/DNA interaction is a druggable target for Hedgehog-dependent tumors.
Volume: 34
Issue: 2
Pages: 200-17
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Publication
26935062 | J:277271
First Author: Di Pietro C
Year: 2017
Journal: Cell Mol Neurobiol
Title: Primary Cilia in the Murine Cerebellum and in Mutant Models of Medulloblastoma.
Volume: 37
Issue: 1
Pages: 145-154
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Publication
28018222 | J:320231
 
First Author: Ceccarelli M
Year: 2016
Journal: Front Pharmacol
Title: Suppression of Medulloblastoma Lesions by Forced Migration of Preneoplastic Precursor Cells with Intracerebellar Administration of the Chemokine Cxcl3.
Volume: 7
Pages: 484
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Publication
21321199 | J:170330
First Author: Kasper M
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Wounding enhances epidermal tumorigenesis by recruiting hair follicle keratinocytes.
Volume: 108
Issue: 10
Pages: 4099-104
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Publication
21317383 | J:169763
First Author: Uhmann A
Year: 2011
Journal: J Immunol
Title: T cell development critically depends on prethymic stromal patched expression.
Volume: 186
Issue: 6
Pages: 3383-91
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Publication
35725556 | J:325968
First Author: Gong B
Year: 2022
Journal: J Neuroinflammation
Title: Complement C3a activates astrocytes to promote medulloblastoma progression through TNF-α.
Volume: 19
Issue: 1
Pages: 159
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Publication
28100039 | J:260064
First Author: Revenco T
Year: 2017
Journal: Stem Cells
Title: Low Dose Radiation Causes Skin Cancer in Mice and Has a Differential Effect on Distinct Epidermal Stem Cells.
Volume: 35
Issue: 5
Pages: 1355-1364
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Publication
25499213 | J:293442
First Author: Suero-Abreu GA
Year: 2014
Journal: Neoplasia
Title: In vivo Mn-enhanced MRI for early tumor detection and growth rate analysis in a mouse medulloblastoma model.
Volume: 16
Issue: 12
Pages: 993-1006
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Publication
29987839 | J:267425
First Author: Sternberg C
Year: 2018
Journal: Int J Cancer
Title: Synergistic cross-talk of hedgehog and interleukin-6 signaling drives growth of basal cell carcinoma.
Volume: 143
Issue: 11
Pages: 2943-2954
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Publication
25027328 | J:216231
First Author: He P
Year: 2014
Journal: Hum Mol Genet
Title: Deficiency of patched 1-induced Gli1 signal transduction results in astrogenesis in Swedish mutated APP transgenic mice.
Volume: 23
Issue: 24
Pages: 6512-27
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Publication
32078657 | J:285245
First Author: Tirou L
Year: 2020
Journal: PLoS One
Title: C9C5 positive mature oligodendrocytes are a source of Sonic Hedgehog in the mouse brain.
Volume: 15
Issue: 2
Pages: e0229362
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25254344 | J:286216
First Author: Ferent J
Year: 2014
Journal: Stem Cell Reports
Title: Genetic activation of Hedgehog signaling unbalances the rate of neural stem cell renewal by increasing symmetric divisions.
Volume: 3
Issue: 2
Pages: 312-23
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Publication
27492255 | J:241271
 
First Author: Gerling M
Year: 2016
Journal: Nat Commun
Title: Stromal Hedgehog signalling is downregulated in colon cancer and its restoration restrains tumour growth.
Volume: 7
Pages: 12321
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Publication
26773048 | J:230825
First Author: Constantin L
Year: 2016
Journal: Genetics
Title: MicroRNA Biogenesis and Hedgehog-Patched Signaling Cooperate to Regulate an Important Developmental Transition in Granule Cell Development.
Volume: 202
Issue: 3
Pages: 1105-18
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Publication
33976373 | J:308010
First Author: Qiu R
Year: 2021
Journal: Commun Biol
Title: Depletion of kinesin motor KIF20A to target cell fate control suppresses medulloblastoma tumour growth.
Volume: 4
Issue: 1
Pages: 552
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Publication
24141309 | J:207638
First Author: Li P
Year: 2013
Journal: Nat Neurosci
Title: A population of Nestin-expressing progenitors in the cerebellum exhibits increased tumorigenicity.
Volume: 16
Issue: 12
Pages: 1737-44
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Publication
19666565 | J:151950
First Author: Hyman JM
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Small-molecule inhibitors reveal multiple strategies for Hedgehog pathway blockade.
Volume: 106
Issue: 33
Pages: 14132-7
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Publication
16355280 | J:128121
First Author: Chen X
Year: 2006
Journal: J Bone Miner Res
Title: Initial characterization of PTH-related protein gene-driven lacZ expression in the mouse.
Volume: 21
Issue: 1
Pages: 113-23
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Publication
11331587 | J:180492
First Author: Barnes EA
Year: 2001
Journal: EMBO J
Title: Patched1 interacts with cyclin B1 to regulate cell cycle progression.
Volume: 20
Issue: 9
Pages: 2214-23
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10842064 | J:63182
First Author: Maye P
Year: 2000
Journal: Mech Dev
Title: Indian hedgehog signaling in extraembryonic endoderm and ectoderm differentiation in ES embryoid bodies.
Volume: 94
Issue: 1-2
Pages: 117-32
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9598353 | J:46793
 
First Author: Johnson RL
Year: 1997
Journal: Cold Spring Harb Symp Quant Biol
Title: Control of cell growth and fate by patched genes.
Volume: 62
Pages: 205-15
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21167467 | J:169421
First Author: Klopocki E
Year: 2011
Journal: Am J Hum Genet
Title: Copy-number variations involving the IHH locus are associated with syndactyly and craniosynostosis.
Volume: 88
Issue: 1
Pages: 70-5
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Publication
25823816 | J:316999
First Author: Nitzki F
Year: 2015
Journal: Oncotarget
Title: Overexpression of mutant Ptch in rhabdomyosarcomas is associated with promoter hypomethylation and increased Gli1 and H3K4me3 occupancy.
Volume: 6
Issue: 11
Pages: 9113-24
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Publication
23014696 | J:188997
First Author: Su CY
Year: 2012
Journal: Development
Title: Temporal deletion of Arl13b reveals that a mispatterned neural tube corrects cell fate over time.
Volume: 139
Issue: 21
Pages: 4062-71
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Publication
18957550 | J:144057
First Author: Hockman D
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: A second wave of Sonic hedgehog expression during the development of the bat limb.
Volume: 105
Issue: 44
Pages: 16982-7
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Publication
31987884 | J:293860
First Author: Becker M
Year: 2020
Journal: J Invest Dermatol
Title: WIF1 Suppresses the Generation of Suprabasal Cells in Acanthotic Skin and Growth of Basal Cell Carcinomas upon Forced Overexpression.
Volume: 140
Issue: 8
Pages: 1556-1565.e11
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Publication
38946128 | J:350486
   
First Author: Ceccarelli M
Year: 2024
Journal: Brain Pathol
Title: Intracerebellar administration of the chemokine Cxcl3 reduces the volume of medulloblastoma lesions at an advanced stage by promoting the migration and differentiation of preneoplastic precursor cells.
Pages: e13283
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Publication
- | J:23861
 
First Author: Sweet HO
Year: 1988
Journal: Mouse News Lett
Title: Mesenchymal dysplasia (mes)
Volume: 81
Pages: 70
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16632755 | J:303480
First Author: Nakatomi M
Year: 2006
Journal: J Dent Res
Title: Sonic hedgehog signaling is important in tooth root development.
Volume: 85
Issue: 5
Pages: 427-31
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25639612 | J:224019
First Author: Hemmesi K
Year: 2015
Journal: Stem Cells
Title: miR-135a Inhibits Cancer Stem Cell-Driven Medulloblastoma Development by Directly Repressing Arhgef6 Expression.
Volume: 33
Issue: 5
Pages: 1377-89
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Publication
35925047 | J:350304
First Author: Yang F
Year: 2022
Journal: Mol Cancer Res
Title: A Druggable UHRF1/DNMT1/GLI Complex Regulates Sonic Hedgehog-Dependent Tumor Growth.
Volume: 20
Issue: 11
Pages: 1598-1610
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22343890 | J:181542
First Author: Wu X
Year: 2012
Journal: Nature
Title: Clonal selection drives genetic divergence of metastatic medulloblastoma.
Volume: 482
Issue: 7386
Pages: 529-33
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15380514 | J:93535
First Author: Romer JT
Year: 2004
Journal: Cancer Cell
Title: Suppression of the Shh pathway using a small molecule inhibitor eliminates medulloblastoma in Ptc1(+/-)p53(-/-) mice.
Volume: 6
Issue: 3
Pages: 229-40
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Publication
31594641 | J:291392
First Author: Song H
Year: 2019
Journal: Biochem Biophys Res Commun
Title: Targeting cyclin-dependent kinase 9 sensitizes medulloblastoma cells to chemotherapy.
Volume: 520
Issue: 2
Pages: 250-256
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Publication
25175806 | J:214800
First Author: Gustafson WC
Year: 2014
Journal: Cancer Cell
Title: Drugging MYCN through an allosteric transition in Aurora kinase A.
Volume: 26
Issue: 3
Pages: 414-427
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Publication
35857834 | J:327233
First Author: Swiderska-Syn M
Year: 2022
Journal: Sci Adv
Title: Noncanonical activation of GLI signaling in SOX2+ cells drives medulloblastoma relapse.
Volume: 8
Issue: 29
Pages: eabj9138
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Publication
21123452 | J:168107
First Author: Dijkgraaf GJ
Year: 2011
Journal: Cancer Res
Title: Small molecule inhibition of GDC-0449 refractory smoothened mutants and downstream mechanisms of drug resistance.
Volume: 71
Issue: 2
Pages: 435-44
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12202832 | J:79798
First Author: Berman DM
Year: 2002
Journal: Science
Title: Medulloblastoma growth inhibition by hedgehog pathway blockade.
Volume: 297
Issue: 5586
Pages: 1559-61
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Publication
34673573 | J:316312
 
First Author: Conti V
Year: 2021
Journal: JCI Insight
Title: mTORC1 promotes malignant large cell/anaplastic histology and is a targetable vulnerability in SHH-TP53 mutant medulloblastoma.
Volume: 6
Issue: 23
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28714964 | J:248158
First Author: Rodriguez-Blanco J
Year: 2017
Journal: Oncogene
Title: Inhibition of WNT signaling attenuates self-renewal of SHH-subgroup medulloblastoma.
Volume: 36
Issue: 45
Pages: 6306-6314
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Publication
22628409 | J:193066
First Author: Corno D
Year: 2012
Journal: Cancer Discov
Title: Gene signatures associated with mouse postnatal hindbrain neural stem cells and medulloblastoma cancer stem cells identify novel molecular mediators and predict human medulloblastoma molecular classification.
Volume: 2
Issue: 6
Pages: 554-68
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Publication
36688010 | J:350106
First Author: George J
Year: 2022
Journal: Cancer Res Commun
Title: Cancer stem cells, not bulk tumor cells, determine mechanisms of resistance to SMO inhibitors.
Volume: 2
Issue: 6
Pages: 402-416
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19147535 | J:205254
First Author: Ayrault O
Year: 2009
Journal: Mol Cancer Res
Title: Two tumor suppressors, p27Kip1 and patched-1, collaborate to prevent medulloblastoma.
Volume: 7
Issue: 1
Pages: 33-40
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Publication
19155313 | J:144974
First Author: Ecke I
Year: 2009
Journal: Cancer Res
Title: Antitumor effects of a combined 5-aza-2'deoxycytidine and valproic acid treatment on rhabdomyosarcoma and medulloblastoma in Ptch mutant mice.
Volume: 69
Issue: 3
Pages: 887-95
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21602884 | J:178576
First Author: Mancuso M
Year: 2011
Journal: Oncogene
Title: Role of connexin43 and ATP in long-range bystander radiation damage and oncogenesis in vivo.
Volume: 30
Issue: 45
Pages: 4601-8
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22438824 | J:183478
First Author: Haag D
Year: 2012
Journal: PLoS Genet
Title: Nos2 inactivation promotes the development of medulloblastoma in Ptch1(+/-) mice by deregulation of Gap43-dependent granule cell precursor migration.
Volume: 8
Issue: 3
Pages: e1002572
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27823583 | J:239107
   
First Author: Bassett EA
Year: 2016
Journal: Elife
Title: Norrin/Frizzled4 signalling in the preneoplastic niche blocks medulloblastoma initiation.
Volume: 5
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17599824 | J:124121
First Author: Galvin KE
Year: 2007
Journal: Dev Biol
Title: Differential gene induction by genetic and ligand-mediated activation of the Sonic hedgehog pathway in neural stem cells.
Volume: 308
Issue: 2
Pages: 331-42
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22354771 | J:343845
First Author: Horn A
Year: 2012
Journal: Arthritis Rheum
Title: Hedgehog signaling controls fibroblast activation and tissue fibrosis in systemic sclerosis.
Volume: 64
Issue: 8
Pages: 2724-33
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23000969 | J:222841
First Author: García-Zaragoza E
Year: 2012
Journal: Dev Biol
Title: Intraepithelial paracrine Hedgehog signaling induces the expansion of ciliated cells that express diverse progenitor cell markers in the basal epithelium of the mouse mammary gland.
Volume: 372
Issue: 1
Pages: 28-44
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Publication
24092639 | J:204594
First Author: Engevik AC
Year: 2013
Journal: Endocrinology
Title: The acid-secreting parietal cell as an endocrine source of Sonic Hedgehog during gastric repair.
Volume: 154
Issue: 12
Pages: 4627-39
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Publication
18772113 | J:141160
First Author: Dierks C
Year: 2008
Journal: Cancer Cell
Title: Expansion of Bcr-Abl-positive leukemic stem cells is dependent on Hedgehog pathway activation.
Volume: 14
Issue: 3
Pages: 238-49
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Publication
20385363 | J:158946
First Author: Kim J
Year: 2010
Journal: Cancer Cell
Title: Itraconazole, a commonly used antifungal that inhibits Hedgehog pathway activity and cancer growth.
Volume: 17
Issue: 4
Pages: 388-99
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Publication
39290714 | J:354888
 
First Author: Shiohama T
Year: 2024
Journal: Front Neurosci
Title: Brain morphological analysis in mice with hyperactivation of the hedgehog signaling pathway.
Volume: 18
Pages: 1449673
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Publication
26509735 | J:229168
First Author: Singh N
Year: 2016
Journal: Dev Dyn
Title: Chronic up-regulation of sonic hedgehog has little effect on postnatal craniofacial morphology of euploid and trisomic mice.
Volume: 245
Issue: 2
Pages: 114-22
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Publication
24167280 | J:202890
First Author: Genovesi LA
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Sleeping Beauty mutagenesis in a mouse medulloblastoma model defines networks that discriminate between human molecular subgroups.
Volume: 110
Issue: 46
Pages: E4325-34
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Publication
21969549 | J:177455
First Author: Jiang D
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Full p53 transcriptional activation potential is dispensable for tumor suppression in diverse lineages.
Volume: 108
Issue: 41
Pages: 17123-8
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Publication
21215705 | J:168256
First Author: Wang GY
Year: 2011
Journal: Cancer Cell
Title: Basal cell carcinomas arise from hair follicle stem cells in Ptch1(+/-) mice.
Volume: 19
Issue: 1
Pages: 114-24
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