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Search results 201 to 300 out of 2547 for Pten

Category restricted to Publication (x)

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Categories

Category: Publication
Type Details Score
Publication
First Author: Wen Y
Year: 2013
Journal: Aging Dis
Title: Astroglial PTEN Loss Disrupts Neuronal Lamination by Dysregulating Radial Glia-guided Neuronal Migration.
Volume: 4
Issue: 3
Pages: 113-26
Publication
First Author: Rangel R
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Transposon mutagenesis identifies genes that cooperate with mutant Pten in breast cancer progression.
Volume: 113
Issue: 48
Pages: E7749-E7758
Publication
First Author: Francis JC
Year: 2013
Journal: PLoS Genet
Title: β-catenin is required for prostate development and cooperates with Pten loss to drive invasive carcinoma.
Volume: 9
Issue: 1
Pages: e1003180
Publication  
First Author: Gallent EA
Year: 2018
Journal: Exp Neurol
Title: Neuronal PTEN deletion in adult cortical neurons triggers progressive growth of cell bodies, dendrites, and axons.
Volume: 303
Pages: 12-28
Publication
First Author: Shi Y
Year: 2020
Journal: Am J Physiol Renal Physiol
Title: Downregulation of PTEN promotes podocyte endocytosis of lipids aggravating obesity-related glomerulopathy.
Volume: 318
Issue: 3
Pages: F589-F599
Publication
First Author: Sanchez-Gurmaches J
Year: 2012
Journal: Cell Metab
Title: PTEN loss in the Myf5 lineage redistributes body fat and reveals subsets of white adipocytes that arise from Myf5 precursors.
Volume: 16
Issue: 3
Pages: 348-62
Publication
First Author: Wang Q
Year: 2013
Journal: Genes Dev
Title: Spatially distinct roles of class Ia PI3K isoforms in the development and maintenance of PTEN hamartoma tumor syndrome.
Volume: 27
Issue: 14
Pages: 1568-80
Publication
First Author: Laguë MN
Year: 2008
Journal: Carcinogenesis
Title: Synergistic effects of Pten loss and WNT/CTNNB1 signaling pathway activation in ovarian granulosa cell tumor development and progression.
Volume: 29
Issue: 11
Pages: 2062-72
Publication
First Author: Palian BM
Year: 2014
Journal: PLoS Genet
Title: Maf1 is a novel target of PTEN and PI3K signaling that negatively regulates oncogenesis and lipid metabolism.
Volume: 10
Issue: 12
Pages: e1004789
Publication
First Author: Kwon CH
Year: 2006
Journal: Neuron
Title: Pten regulates neuronal arborization and social interaction in mice.
Volume: 50
Issue: 3
Pages: 377-88
Publication
First Author: Sizemore GM
Year: 2018
Journal: Nat Commun
Title: Stromal PTEN determines mammary epithelial response to radiotherapy.
Volume: 9
Issue: 1
Pages: 2783
Publication
First Author: Alimonti A
Year: 2010
Journal: Nat Genet
Title: Subtle variations in Pten dose determine cancer susceptibility.
Volume: 42
Issue: 5
Pages: 454-8
Publication  
First Author: Baohan A
Year: 2016
Journal: Nat Commun
Title: Pten and EphB4 regulate the establishment of perisomatic inhibition in mouse visual cortex.
Volume: 7
Pages: 12829
Publication
First Author: Stiles BL
Year: 2006
Journal: Mol Cell Biol
Title: Selective deletion of Pten in pancreatic beta cells leads to increased islet mass and resistance to STZ-induced diabetes.
Volume: 26
Issue: 7
Pages: 2772-81
Publication
First Author: Papa A
Year: 2014
Journal: Cell
Title: Cancer-associated PTEN mutants act in a dominant-negative manner to suppress PTEN protein function.
Volume: 157
Issue: 3
Pages: 595-610
Publication
First Author: Xu B
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: PTEN signaling through RAF1 proto-oncogene serine/threonine kinase (RAF1)/ERK in the epididymis is essential for male fertility.
Volume: 111
Issue: 52
Pages: 18643-8
Publication
First Author: Chen Y
Year: 2013
Journal: Nat Med
Title: ETS factors reprogram the androgen receptor cistrome and prime prostate tumorigenesis in response to PTEN loss.
Volume: 19
Issue: 8
Pages: 1023-9
Publication
First Author: Li G
Year: 2002
Journal: Development
Title: Conditional loss of PTEN leads to precocious development and neoplasia in the mammary gland.
Volume: 129
Issue: 17
Pages: 4159-70
Publication
First Author: Jones CE
Year: 2021
Journal: PLoS One
Title: Pten regulates collagen fibrillogenesis by fibroblasts through SPARC.
Volume: 16
Issue: 2
Pages: e0245653
Publication
First Author: Frew IJ
Year: 2008
Journal: Mol Cell Biol
Title: Combined VHLH and PTEN mutation causes genital tract cystadenoma and squamous metaplasia.
Volume: 28
Issue: 14
Pages: 4536-48
Publication
First Author: Antico Arciuch VG
Year: 2011
Journal: Oncotarget
Title: Thyrocyte-specific inactivation of p53 and Pten results in anaplastic thyroid carcinomas faithfully recapitulating human tumors.
Volume: 2
Issue: 12
Pages: 1109-26
Publication
First Author: Clipperton-Allen AE
Year: 2014
Journal: Hum Mol Genet
Title: Pten haploinsufficient mice show broad brain overgrowth but selective impairments in autism-relevant behavioral tests.
Volume: 23
Issue: 13
Pages: 3490-505
Publication
First Author: Joshi A
Year: 2015
Journal: Am J Pathol
Title: Activated mutant p110α causes endometrial carcinoma in the setting of biallelic Pten deletion.
Volume: 185
Issue: 4
Pages: 1104-13
Publication
First Author: Langdon CG
Year: 2021
Journal: Nat Commun
Title: Synthetic essentiality between PTEN and core dependency factor PAX7 dictates rhabdomyosarcoma identity.
Volume: 12
Issue: 1
Pages: 5520
Publication
First Author: Fu Y
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Pten null prostate tumorigenesis and AKT activation are blocked by targeted knockout of ER chaperone GRP78/BiP in prostate epithelium.
Volume: 105
Issue: 49
Pages: 19444-9
Publication    
First Author: González-Fernández E
Year: 2018
Journal: Elife
Title: PTEN negatively regulates the cell lineage progression from NG2+ glial progenitor to oligodendrocyte via mTOR-independent signaling.
Volume: 7
Publication
First Author: Melchor L
Year: 2014
Journal: J Pathol
Title: Identification of cellular and genetic drivers of breast cancer heterogeneity in genetically engineered mouse tumour models.
Volume: 233
Issue: 2
Pages: 124-37
Publication  
First Author: Liu Y
Year: 2024
Journal: Free Radic Biol Med
Title: Regulation of YAP translocation by myeloid Pten deficiency alleviates acute lung injury via inhibition of oxidative stress and inflammation.
Volume: 222
Pages: 199-210
Publication
First Author: Kim HJ
Year: 2013
Journal: PLoS One
Title: Conditional deletion of pten leads to defects in nerve innervation and neuronal survival in inner ear development.
Volume: 8
Issue: 2
Pages: e55609
Publication
First Author: Wang J
Year: 2012
Journal: Cancer Res
Title: B-Raf activation cooperates with PTEN loss to drive c-Myc expression in advanced prostate cancer.
Volume: 72
Issue: 18
Pages: 4765-76
Publication
First Author: Sementino E
Year: 2018
Journal: J Cell Physiol
Title: Inactivation of Tp53 and Pten drives rapid development of pleural and peritoneal malignant mesotheliomas.
Volume: 233
Issue: 11
Pages: 8952-8961
Publication
First Author: Xu C
Year: 2014
Journal: Cancer Cell
Title: Loss of Lkb1 and Pten leads to lung squamous cell carcinoma with elevated PD-L1 expression.
Volume: 25
Issue: 5
Pages: 590-604
Publication
First Author: Zhang Y
Year: 2012
Journal: Brain
Title: PTEN deletion enhances survival, neurite outgrowth and function of dopamine neuron grafts to MitoPark mice.
Volume: 135
Issue: Pt 9
Pages: 2736-49
Publication
First Author: Yu M
Year: 2014
Journal: Oncogene
Title: Inactivation of TGF-β signaling and loss of PTEN cooperate to induce colon cancer in vivo.
Volume: 33
Issue: 12
Pages: 1538-47
Publication
First Author: Ghosh S
Year: 2013
Journal: Cancer Res
Title: mTOR signaling feedback modulates mammary epithelial differentiation and restrains invasion downstream of PTEN loss.
Volume: 73
Issue: 16
Pages: 5218-31
Publication
First Author: Zhang SJ
Year: 2019
Journal: Biochem Biophys Res Commun
Title: Schwann cell-specific PTEN and EGFR dysfunctions affect neuromuscular junction development by impairing Agrin signaling and autophagy.
Volume: 515
Issue: 1
Pages: 50-56
Publication
First Author: Filtz EA
Year: 2015
Journal: PLoS One
Title: Rb1 and Pten Co-Deletion in Osteoblast Precursor Cells Causes Rapid Lipoma Formation in Mice.
Volume: 10
Issue: 8
Pages: e0136729
Publication
First Author: Lu S
Year: 2020
Journal: Arterioscler Thromb Vasc Biol
Title: PTEN (Phosphatase and Tensin Homolog) Protects Against Ang II (Angiotensin II)-Induced Pathological Vascular Fibrosis and Remodeling-Brief Report.
Volume: 40
Issue: 2
Pages: 394-403
Publication
First Author: Wozniak DJ
Year: 2017
Journal: Nat Commun
Title: PTEN is a protein phosphatase that targets active PTK6 and inhibits PTK6 oncogenic signaling in prostate cancer.
Volume: 8
Issue: 1
Pages: 1508
Publication
First Author: Shen WH
Year: 2007
Journal: Cell
Title: Essential role for nuclear PTEN in maintaining chromosomal integrity.
Volume: 128
Issue: 1
Pages: 157-70
Publication
First Author: Tu WL
Year: 2018
Journal: Am J Pathol
Title: Pten Haplodeficiency Accelerates Liver Tumor Growth in miR-122a-Null Mice via Expansion of Periportal Hepatocyte-Like Cells.
Volume: 188
Issue: 11
Pages: 2688-2702
Publication
First Author: Valiente M
Year: 2005
Journal: J Biol Chem
Title: Binding of PTEN to specific PDZ domains contributes to PTEN protein stability and phosphorylation by microtubule-associated serine/threonine kinases.
Volume: 280
Issue: 32
Pages: 28936-43
Publication
First Author: Mulholland DJ
Year: 2011
Journal: Cancer Cell
Title: Cell autonomous role of PTEN in regulating castration-resistant prostate cancer growth.
Volume: 19
Issue: 6
Pages: 792-804
Publication
First Author: Kato T
Year: 2020
Journal: iScience
Title: The Loss of Nuclear PTEN Increases Tumorigenesis in a Preclinical Mouse Model for Hepatocellular Carcinoma.
Volume: 23
Issue: 10
Pages: 101548
Publication
First Author: Akins EJ
Year: 2010
Journal: Cancer Res
Title: In situ vaccination combined with androgen ablation and regulatory T-cell depletion reduces castration-resistant tumor burden in prostate-specific pten knockout mice.
Volume: 70
Issue: 9
Pages: 3473-82
Publication
First Author: Yeager N
Year: 2007
Journal: Cancer Res
Title: Pten loss in the mouse thyroid causes goiter and follicular adenomas: insights into thyroid function and Cowden disease pathogenesis.
Volume: 67
Issue: 3
Pages: 959-66
Publication
First Author: Vignarajan S
Year: 2014
Journal: Oncotarget
Title: Loss of PTEN stabilizes the lipid modifying enzyme cytosolic phospholipase A₂α via AKT in prostate cancer cells.
Volume: 5
Issue: 15
Pages: 6289-99
Publication
First Author: Su Q
Year: 2017
Journal: Oncogene
Title: Jagged1 upregulation in prostate epithelial cells promotes formation of reactive stroma in the Pten null mouse model for prostate cancer.
Volume: 36
Issue: 5
Pages: 618-627
Publication
First Author: Li XX
Year: 2020
Journal: Biochem Biophys Res Commun
Title: Schwann cell-specific Pten inactivation reveals essential role of the sympathetic nervous system activity in adipose tissue development.
Volume: 531
Issue: 2
Pages: 118-124
Publication  
First Author: Yue F
Year: 2017
Journal: Nat Commun
Title: Pten is necessary for the quiescence and maintenance of adult muscle stem cells.
Volume: 8
Pages: 14328
Publication
First Author: Macdonald FH
Year: 2014
Journal: Oncogene
Title: PTEN ablation in Ras(Ha)/Fos skin carcinogenesis invokes p53-dependent p21 to delay conversion while p53-independent p21 limits progression via cyclin D1/E2 inhibition.
Volume: 33
Issue: 32
Pages: 4132-43
Publication
First Author: Trimboli AJ
Year: 2009
Journal: Nature
Title: Pten in stromal fibroblasts suppresses mammary epithelial tumours.
Volume: 461
Issue: 7267
Pages: 1084-91
Publication
First Author: Newton RH
Year: 2015
Journal: Blood
Title: Suppression of T-cell lymphomagenesis in mice requires PTEN phosphatase activity.
Volume: 125
Issue: 5
Pages: 852-5
Publication  
First Author: He J
Year: 2015
Journal: Nat Commun
Title: PTEN regulates DNA replication progression and stalled fork recovery.
Volume: 6
Pages: 7620
Publication
First Author: Wijesekara N
Year: 2005
Journal: Mol Cell Biol
Title: Muscle-specific Pten deletion protects against insulin resistance and diabetes.
Volume: 25
Issue: 3
Pages: 1135-45
Publication
First Author: Xu Z
Year: 2023
Journal: Cell Rep
Title: PTEN regulates hematopoietic lineage plasticity via PU.1-dependent chromatin accessibility.
Volume: 42
Issue: 8
Pages: 112967
Publication
First Author: Jang HD
Year: 2013
Journal: Bone
Title: PTEN regulation by the Akt/GSK-3β axis during RANKL signaling.
Volume: 55
Issue: 1
Pages: 126-31
Publication  
First Author: Danilov CA
Year: 2015
Journal: Exp Neurol
Title: Conditional genetic deletion of PTEN after a spinal cord injury enhances regenerative growth of CST axons and motor function recovery in mice.
Volume: 266
Pages: 147-60
Publication
First Author: Kwak MK
Year: 2013
Journal: PLoS One
Title: Conditional deletion of the Pten gene in the mouse prostate induces prostatic intraepithelial neoplasms at early ages but a slow progression to prostate tumors.
Volume: 8
Issue: 1
Pages: e53476
Publication
First Author: Yao D
Year: 2006
Journal: Cancer Res
Title: PTEN loss promotes rasHa-mediated papillomatogenesis via dual up-regulation of AKT activity and cell cycle deregulation but malignant conversion proceeds via PTEN-associated pathways.
Volume: 66
Issue: 3
Pages: 1302-12
Publication
First Author: Meng Y
Year: 2017
Journal: Dev Dyn
Title: Pten facilitates epiblast epithelial polarization and proamniotic lumen formation in early mouse embryos.
Volume: 246
Issue: 7
Pages: 517-530
Publication
First Author: Kopp JL
Year: 2018
Journal: Gastroenterology
Title: Loss of Pten and Activation of Kras Synergistically Induce Formation of Intraductal Papillary Mucinous Neoplasia From Pancreatic Ductal Cells in Mice.
Volume: 154
Issue: 5
Pages: 1509-1523.e5
Publication
First Author: Miething C
Year: 2014
Journal: Nature
Title: PTEN action in leukaemia dictated by the tissue microenvironment.
Volume: 510
Issue: 7505
Pages: 402-6
Publication
First Author: Stanger BZ
Year: 2005
Journal: Cancer Cell
Title: Pten constrains centroacinar cell expansion and malignant transformation in the pancreas.
Volume: 8
Issue: 3
Pages: 185-95
Publication
First Author: Shearn CT
Year: 2014
Journal: PLoS One
Title: Short term feeding of a high fat diet exerts an additive effect on hepatocellular damage and steatosis in liver-specific PTEN knockout mice.
Volume: 9
Issue: 5
Pages: e96553
Publication
First Author: Maire CL
Year: 2014
Journal: Stem Cells
Title: Pten loss in Olig2 expressing neural progenitor cells and oligodendrocytes leads to interneuron dysplasia and leukodystrophy.
Volume: 32
Issue: 1
Pages: 313-26
Publication
First Author: Li L
Year: 2003
Journal: J Cell Biochem
Title: PTEN regulation of neural development and CNS stem cells.
Volume: 88
Issue: 1
Pages: 24-8
Publication
First Author: Zhang J
Year: 2019
Journal: Cancer Discov
Title: PTEN Methylation by NSD2 Controls Cellular Sensitivity to DNA Damage.
Volume: 9
Issue: 9
Pages: 1306-1323
Publication  
First Author: Li Y
Year: 2001
Journal: BMC Mol Biol
Title: Deficiency of Pten accelerates mammary oncogenesis in MMTV-Wnt-1 transgenic mice.
Volume: 2
Pages: 2
Publication
First Author: Jones CE
Year: 2019
Journal: Neoplasia
Title: Stromal PTEN Regulates Extracellular Matrix Organization in the Mammary Gland.
Volume: 21
Issue: 1
Pages: 132-145
Publication
First Author: Haws ME
Year: 2014
Journal: J Comp Neurol
Title: PTEN knockdown alters dendritic spine/protrusion morphology, not density.
Volume: 522
Issue: 5
Pages: 1171-90
Publication
First Author: Clipperton-Allen AE
Year: 2015
Journal: Genes Brain Behav
Title: Decreased aggression and increased repetitive behavior in Pten haploinsufficient mice.
Volume: 14
Issue: 2
Pages: 145-57
Publication
First Author: Wong JT
Year: 2007
Journal: Diabetologia
Title: Pten (phosphatase and tensin homologue gene) haploinsufficiency promotes insulin hypersensitivity.
Volume: 50
Issue: 2
Pages: 395-403
Publication
First Author: Horie Y
Year: 2004
Journal: J Clin Invest
Title: Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas.
Volume: 113
Issue: 12
Pages: 1774-83
Publication
First Author: Korpershoek E
Year: 2009
Journal: J Pathol
Title: Conditional Pten knock-out mice: a model for metastatic phaeochromocytoma.
Volume: 217
Issue: 4
Pages: 597-604
Publication
First Author: He X
Year: 2013
Journal: Cancer Res
Title: Cowden syndrome-related mutations in PTEN associate with enhanced proteasome activity.
Volume: 73
Issue: 10
Pages: 3029-40
Publication
First Author: Yamaguchi Y
Year: 2010
Journal: Mutat Res
Title: Complicated biallelic inactivation of Pten in radiation-induced mouse thymic lymphomas.
Volume: 686
Issue: 1-2
Pages: 30-8
Publication
First Author: Gu T
Year: 2011
Journal: Cancer Res
Title: CREB is a novel nuclear target of PTEN phosphatase.
Volume: 71
Issue: 8
Pages: 2821-5
Publication
First Author: Wang H
Year: 2018
Journal: Am J Physiol Renal Physiol
Title: Podocyte-specific knockin of PTEN protects kidney from hyperglycemia.
Volume: 314
Issue: 6
Pages: F1096-F1107
Publication
First Author: Malkoski SP
Year: 2014
Journal: Mol Carcinog
Title: Role of PTEN in basal cell derived lung carcinogenesis.
Volume: 53
Issue: 10
Pages: 841-6
Publication
First Author: Guntur AR
Year: 2011
Journal: Development
Title: Conditional ablation of Pten in osteoprogenitors stimulates FGF signaling.
Volume: 138
Issue: 7
Pages: 1433-44
Publication
First Author: Diaz-Ruiz O
Year: 2009
Journal: PLoS One
Title: Selective deletion of PTEN in dopamine neurons leads to trophic effects and adaptation of striatal medium spiny projecting neurons.
Volume: 4
Issue: 9
Pages: e7027
Publication
First Author: Jolly LA
Year: 2016
Journal: Cancer Res
Title: Fibroblast-Mediated Collagen Remodeling Within the Tumor Microenvironment Facilitates Progression of Thyroid Cancers Driven by BrafV600E and Pten Loss.
Volume: 76
Issue: 7
Pages: 1804-13
Publication
First Author: Sharma MD
Year: 2015
Journal: Sci Adv
Title: The PTEN pathway in Tregs is a critical driver of the suppressive tumor microenvironment.
Volume: 1
Issue: 10
Pages: e1500845
Publication  
First Author: Igarashi A
Year: 2021
Journal: Biochem Biophys Res Commun
Title: Nuclear PTEN deficiency and heterozygous PTEN loss have distinct impacts on brain and lymph node size.
Volume: 555
Pages: 81-88
Publication  
First Author: Kim TH
Year: 2010
Journal: J Oncol
Title: The Synergistic Effect of Conditional Pten Loss and Oncogenic K-ras Mutation on Endometrial Cancer Development Occurs via Decreased Progesterone Receptor Action.
Volume: 2010
Pages: 139087
Publication
First Author: Bilir B
Year: 2016
Journal: Cancer Res
Title: SOX4 Is Essential for Prostate Tumorigenesis Initiated by PTEN Ablation.
Volume: 76
Issue: 5
Pages: 1112-21
Publication
First Author: Chang CJ
Year: 2004
Journal: J Biol Chem
Title: PTEN regulates Mdm2 expression through the P1 promoter.
Volume: 279
Issue: 28
Pages: 29841-8
Publication
First Author: Weng Q
Year: 2020
Journal: Cell Death Differ
Title: STAT3 dictates β-cell apoptosis by modulating PTEN in streptozocin-induced hyperglycemia.
Volume: 27
Issue: 1
Pages: 130-145
Publication
First Author: To MD
Year: 2005
Journal: Cell Cycle
Title: Crosstalk between Pten and Ras signaling pathways in tumor development.
Volume: 4
Issue: 9
Pages: 1185-8
Publication
First Author: Fuentes ME
Year: 2024
Journal: Sci Rep
Title: Combined deletion of MEN1, ATRX and PTEN triggers development of high-grade pancreatic neuroendocrine tumors in mice.
Volume: 14
Issue: 1
Pages: 8510
Publication
First Author: Jo HS
Year: 2012
Journal: EMBO J
Title: Pten coordinates retinal neurogenesis by regulating Notch signalling.
Volume: 31
Issue: 4
Pages: 817-28
Publication
First Author: Korsten H
Year: 2016
Journal: PLoS One
Title: Characterization of Heterogeneous Prostate Tumors in Targeted Pten Knockout Mice.
Volume: 11
Issue: 1
Pages: e0147500
Publication
First Author: Zhang L
Year: 2015
Journal: Nature
Title: Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth.
Volume: 527
Issue: 7576
Pages: 100-104
Publication
First Author: Yao D
Year: 2008
Journal: J Cell Sci
Title: Fos cooperation with PTEN loss elicits keratoacanthoma not carcinoma, owing to p53/p21 WAF-induced differentiation triggered by GSK3beta inactivation and reduced AKT activity.
Volume: 121
Issue: Pt 10
Pages: 1758-69
Publication
First Author: Cheng H
Year: 2014
Journal: Cancer Res
Title: A genetic mouse model of invasive endometrial cancer driven by concurrent loss of Pten and Lkb1 Is highly responsive to mTOR inhibition.
Volume: 74
Issue: 1
Pages: 15-23
Publication
First Author: Huang F
Year: 2024
Journal: J Transl Med
Title: PTEN deficiency potentiates HBV-associated liver cancer development through augmented GP73/GOLM1.
Volume: 22
Issue: 1
Pages: 254
Publication
First Author: Wang L
Year: 2010
Journal: Diabetes
Title: Deletion of Pten in pancreatic ß-cells protects against deficient ß-cell mass and function in mouse models of type 2 diabetes.
Volume: 59
Issue: 12
Pages: 3117-26
Publication
First Author: Bian Y
Year: 2012
Journal: Oncogene
Title: Loss of TGF-β signaling and PTEN promotes head and neck squamous cell carcinoma through cellular senescence evasion and cancer-related inflammation.
Volume: 31
Issue: 28
Pages: 3322-32
Publication
First Author: Ma WT
Year: 2017
Journal: Cell Death Dis
Title: Modulation of liver regeneration via myeloid PTEN deficiency.
Volume: 8
Issue: 5
Pages: e2827