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Search results 201 to 300 out of 430 for Ptpn11

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Type Details Score
Publication
9867848 | J:51814
First Author: Huber M
Year: 1999
Journal: J Biol Chem
Title: The carboxyl-terminal region of biliary glycoprotein controls its tyrosine phosphorylation and association with protein-tyrosine phosphatases SHP-1 and SHP-2 in epithelial cells.
Volume: 274
Issue: 1
Pages: 335-44
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Publication
11739737 | J:78670
First Author: Wolf I
Year: 2002
Journal: Mol Cell Biol
Title: Gab3, a new DOS/Gab family member, facilitates macrophage differentiation.
Volume: 22
Issue: 1
Pages: 231-44
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Publication
9070220 | J:38263
First Author: Yamao T
Year: 1997
Journal: Biochem Biophys Res Commun
Title: Mouse and human SHPS-1: molecular cloning of cDNAs and chromosomal localization of genes.
Volume: 231
Issue: 1
Pages: 61-7
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Publication
8096088 | J:19469
First Author: Feng GS
Year: 1993
Journal: Science
Title: SH2-containing phosphotyrosine phosphatase as a target of protein-tyrosine kinases.
Volume: 259
Issue: 5101
Pages: 1607-11
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Publication
22806893 | J:189153
First Author: Mali RS
Year: 2012
Journal: Blood
Title: Role of SHP2 phosphatase in KIT-induced transformation: identification of SHP2 as a druggable target in diseases involving oncogenic KIT.
Volume: 120
Issue: 13
Pages: 2669-78
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Publication
30926899 | J:273850
First Author: Niogret C
Year: 2019
Journal: Nat Commun
Title: Shp-2 is critical for ERK and metabolic engagement downstream of IL-15 receptor in NK cells.
Volume: 10
Issue: 1
Pages: 1444
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Publication
36979407 | J:336332
 
First Author: Bono F
Year: 2023
Journal: Biomolecules
Title: G Protein-Dependent Activation of the PKA-Erk1/2 Pathway by the Striatal Dopamine D1/D3 Receptor Heteromer Involves Beta-Arrestin and the Tyrosine Phosphatase Shp-2.
Volume: 13
Issue: 3
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Publication
28701303 | J:253324
First Author: Yan M
Year: 2017
Journal: FASEB J
Title: Endothelial cell SHP-2 negatively regulates neutrophil adhesion and promotes transmigration by enhancing ICAM-1-VE-cadherin interaction.
Volume: 31
Issue: 11
Pages: 4759-4769
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Publication
19679834 | J:169970
First Author: Schröder K
Year: 2009
Journal: Circ Res
Title: NADPH oxidase Nox2 is required for hypoxia-induced mobilization of endothelial progenitor cells.
Volume: 105
Issue: 6
Pages: 537-44
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Publication
19637226 | J:153257
First Author: Fink K
Year: 2009
Journal: Eur J Immunol
Title: Depletion of macrophages in mice results in higher dengue virus titers and highlights the role of macrophages for virus control.
Volume: 39
Issue: 10
Pages: 2809-21
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Publication
21297004 | J:172845
First Author: Ming Z
Year: 2011
Journal: Blood
Title: Lyn and PECAM-1 function as interdependent inhibitors of platelet aggregation.
Volume: 117
Issue: 14
Pages: 3903-6
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Publication
26456821 | J:269458
First Author: Akilli Öztürk Ö
Year: 2015
Journal: Cell Rep
Title: Gab1 and Mapk Signaling Are Essential in the Hair Cycle and Hair Follicle Stem Cell Quiescence.
Volume: 13
Issue: 3
Pages: 561-572
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Publication
21804557 | J:176469
First Author: Pallotta MT
Year: 2011
Journal: Nat Immunol
Title: Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells.
Volume: 12
Issue: 9
Pages: 870-8
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Publication
28287082 | J:244688
 
First Author: Song Y
Year: 2017
Journal: Nat Commun
Title: E3 ligase FBXW7 is critical for RIG-I stabilization during antiviral responses.
Volume: 8
Pages: 14654
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Publication
28814604 | J:251135
First Author: Xu J
Year: 2017
Journal: J Immunol
Title: Macrophage-Restricted Shp2 Tyrosine Phosphatase Acts as a Rheostat for MMP12 through TGF-β Activation in the Prevention of Age-Related Emphysema in Mice.
Volume: 199
Issue: 7
Pages: 2323-2332
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Publication
21450902 | J:177959
First Author: Zhu HH
Year: 2011
Journal: Blood
Title: Kit-Shp2-Kit signaling acts to maintain a functional hematopoietic stem and progenitor cell pool.
Volume: 117
Issue: 20
Pages: 5350-61
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Publication
36528691 | J:332221
First Author: Yan Y
Year: 2022
Journal: Sci Rep
Title: Extracellular arginine is required but the arginine transporter CAT3 (Slc7a3) is dispensable for mouse normal and malignant hematopoiesis.
Volume: 12
Issue: 1
Pages: 21832
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Publication
24553178 | J:210890
First Author: Goodwin CB
Year: 2014
Journal: Blood
Title: PI3K p110δ uniquely promotes gain-of-function Shp2-induced GM-CSF hypersensitivity in a model of JMML.
Volume: 123
Issue: 18
Pages: 2838-42
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Publication
19635473 | J:153547
First Author: Hagihara K
Year: 2009
Journal: Dev Biol
Title: Shp2 acts downstream of SDF-1alpha/CXCR4 in guiding granule cell migration during cerebellar development.
Volume: 334
Issue: 1
Pages: 276-84
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Publication
29505847 | J:320365
First Author: Liu JJ
Year: 2018
Journal: J Hepatol
Title: Shp2 deletion in hepatocytes suppresses hepatocarcinogenesis driven by oncogenic β-Catenin, PIK3CA and MET.
Volume: 69
Issue: 1
Pages: 79-88
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Publication
37846866 | J:358282
   
First Author: Kaneko K
Year: 2023
Journal: Elife
Title: Identification of CD133(+) intercellsomes in intercellular communication to offset intracellular signal deficit.
Volume: 12
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Publication
30837304 | J:284319
 
First Author: Ryu HH
Year: 2019
Journal: Sci Signal
Title: Excitatory neuron-specific SHP2-ERK signaling network regulates synaptic plasticity and memory.
Volume: 12
Issue: 571
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Publication
19001090 | J:144767
First Author: Princen F
Year: 2009
Journal: Mol Cell Biol
Title: Deletion of Shp2 tyrosine phosphatase in muscle leads to dilated cardiomyopathy, insulin resistance, and premature death.
Volume: 29
Issue: 2
Pages: 378-88
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Publication
15699129 | J:96557
First Author: Okazawa H
Year: 2005
Journal: J Immunol
Title: Negative regulation of phagocytosis in macrophages by the CD47-SHPS-1 system.
Volume: 174
Issue: 4
Pages: 2004-11
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Publication
30376595 | J:270196
First Author: Gagné-Sansfacon J
Year: 2019
Journal: J Pathol
Title: The tyrosine phosphatase Shp-2 confers resistance to colonic inflammation by driving goblet cell function and crypt regeneration.
Volume: 247
Issue: 1
Pages: 135-146
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Publication
22759635 | J:185343
First Author: Huang H
Year: 2012
Journal: Genes Dev
Title: A Src family kinase-Shp2 axis controls RUNX1 activity in megakaryocyte and T-lymphocyte differentiation.
Volume: 26
Issue: 14
Pages: 1587-601
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Publication
30102570 | J:283321
First Author: Zhang J
Year: 2019
Journal: FASEB J
Title: SHP2 protects endothelial cell barrier through suppressing VE-cadherin internalization regulated by MET-ARF1.
Volume: 33
Issue: 1
Pages: 1124-1137
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Publication
18378677 | J:137570
First Author: Eminaga S
Year: 2008
Journal: J Biol Chem
Title: Noonan syndrome-associated SHP-2/Ptpn11 mutants enhance SIRPalpha and PZR tyrosyl phosphorylation and promote adhesion-mediated ERK activation.
Volume: 283
Issue: 22
Pages: 15328-38
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Publication
29255148 | J:257673
First Author: Guo W
Year: 2017
Journal: Nat Commun
Title: Tyrosine phosphatase SHP2 negatively regulates NLRP3 inflammasome activation via ANT1-dependent mitochondrial homeostasis.
Volume: 8
Issue: 1
Pages: 2168
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Publication
20160350 | J:158568
First Author: Banno R
Year: 2010
Journal: J Clin Invest
Title: PTP1B and SHP2 in POMC neurons reciprocally regulate energy balance in mice.
Volume: 120
Issue: 3
Pages: 720-34
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Publication
12611902 | J:83590
First Author: Burkart A
Year: 2003
Journal: J Biol Chem
Title: Regulation of the SHP-2 tyrosine phosphatase by a novel cholesterol- and cell confluence-dependent mechanism.
Volume: 278
Issue: 20
Pages: 18360-7
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Publication
8183548 | J:18769
First Author: Feng GS
Year: 1994
Journal: Oncogene
Title: Receptor-binding, tyrosine phosphorylation and chromosome localization of the mouse SH2-containing phosphotyrosine phosphatase Syp.
Volume: 9
Issue: 6
Pages: 1545-50
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Publication
14967925 | J:88403
First Author: Hara KT
Year: 2003
Journal: J Reprod Dev
Title: Dynamic changes in the expression of protein tyrosine phosphatases during preimplantation mouse development: semi-quantification by real-time PCR.
Volume: 49
Issue: 4
Pages: 323-8
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Publication
15169898 | J:91029
First Author: Kontaridis MI
Year: 2004
Journal: Mol Cell Biol
Title: SHP-2 positively regulates myogenesis by coupling to the Rho GTPase signaling pathway.
Volume: 24
Issue: 12
Pages: 5340-52
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Publication
16873377 | J:117169
First Author: Yu M
Year: 2006
Journal: J Biol Chem
Title: The scaffolding adapter Gab2, via Shp-2, regulates kit-evoked mast cell proliferation by activating the Rac/JNK pathway.
Volume: 281
Issue: 39
Pages: 28615-26
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Publication
17369354 | J:120137
First Author: Amin AR
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: SHP-2 tyrosine phosphatase inhibits p73-dependent apoptosis and expression of a subset of p53 target genes induced by EGCG.
Volume: 104
Issue: 13
Pages: 5419-24
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16731527 | J:116450
First Author: Udell CM
Year: 2006
Journal: J Biol Chem
Title: Fer and Fps/Fes participate in a Lyn-dependent pathway from FcepsilonRI to platelet-endothelial cell adhesion molecule 1 to limit mast cell activation.
Volume: 281
Issue: 30
Pages: 20949-57
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Publication
23374343 | J:193456
First Author: Chen W
Year: 2013
Journal: Cell
Title: Induction of Siglec-G by RNA viruses inhibits the innate immune response by promoting RIG-I degradation.
Volume: 152
Issue: 3
Pages: 467-78
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Publication
20526344 | J:161854
First Author: Hitomi K
Year: 2010
Journal: Nat Immunol
Title: An immunoglobulin-like receptor, Allergin-1, inhibits immunoglobulin E-mediated immediate hypersensitivity reactions.
Volume: 11
Issue: 7
Pages: 601-7
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10521483 | J:200516
First Author: Jones N
Year: 1999
Journal: J Biol Chem
Title: Identification of Tek/Tie2 binding partners. Binding to a multifunctional docking site mediates cell survival and migration.
Volume: 274
Issue: 43
Pages: 30896-905
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23112346 | J:201266
First Author: Mazharian A
Year: 2012
Journal: Sci Signal
Title: Mice lacking the ITIM-containing receptor G6b-B exhibit macrothrombocytopenia and aberrant platelet function.
Volume: 5
Issue: 248
Pages: ra78
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12796776 | J:84084
First Author: Watanabe N
Year: 2003
Journal: Nat Immunol
Title: BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1.
Volume: 4
Issue: 7
Pages: 670-9
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15568026 | J:94873
First Author: Sedy JR
Year: 2005
Journal: Nat Immunol
Title: B and T lymphocyte attenuator regulates T cell activation through interaction with herpesvirus entry mediator.
Volume: 6
Issue: 1
Pages: 90-8
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Publication
17239631 | J:118322
First Author: Park-Min KH
Year: 2007
Journal: Immunity
Title: FcgammaRIII-dependent inhibition of interferon-gamma responses mediates suppressive effects of intravenous immune globulin.
Volume: 26
Issue: 1
Pages: 67-78
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Publication
31204070 | J:282651
First Author: Mintz MA
Year: 2019
Journal: Immunity
Title: The HVEM-BTLA Axis Restrains T Cell Help to Germinal Center B Cells and Functions as a Cell-Extrinsic Suppressor in Lymphomagenesis.
Volume: 51
Issue: 2
Pages: 310-323.e7
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Publication
22522491 | J:186456
First Author: Xu S
Year: 2012
Journal: Nat Immunol
Title: Constitutive MHC class I molecules negatively regulate TLR-triggered inflammatory responses via the Fps-SHP-2 pathway.
Volume: 13
Issue: 6
Pages: 551-9
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Publication
25915733 | J:232837
First Author: Deng Z
Year: 2015
Journal: Nat Immunol
Title: Tyrosine phosphatase SHP-2 mediates C-type lectin receptor-induced activation of the kinase Syk and anti-fungal TH17 responses.
Volume: 16
Issue: 6
Pages: 642-52
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Publication
30526882 | J:271404
First Author: Cai Z
Year: 2018
Journal: Cell Stem Cell
Title: Inhibition of Inflammatory Signaling in Tet2 Mutant Preleukemic Cells Mitigates Stress-Induced Abnormalities and Clonal Hematopoiesis.
Volume: 23
Issue: 6
Pages: 833-849.e5
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Publication
21364532 | J:171253
First Author: Fujita Y
Year: 2011
Journal: EMBO J
Title: Myelin suppresses axon regeneration by PIR-B/SHP-mediated inhibition of Trk activity.
Volume: 30
Issue: 7
Pages: 1389-401
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26416283 | J:243470
First Author: Xiao Y
Year: 2015
Journal: J Immunol
Title: Protein Tyrosine Phosphatase SHP-1 Modulates T Cell Responses by Controlling Cbl-b Degradation.
Volume: 195
Issue: 9
Pages: 4218-27
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Publication
20435932 | J:161224
First Author: Zheng Y
Year: 2010
Journal: J Immunol
Title: Scaffolding adaptor protein Gab1 is required for TLR3/4- and RIG-I-mediated production of proinflammatory cytokines and type I IFN in macrophages.
Volume: 184
Issue: 11
Pages: 6447-56
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28344320 | J:249417
First Author: O'Leary HA
Year: 2017
Journal: Leukemia
Title: DPP4 truncated GM-CSF and IL-3 manifest distinct receptor-binding and regulatory functions compared with their full-length forms.
Volume: 31
Issue: 11
Pages: 2468-2478
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12937170 | J:86382
First Author: Yuan L
Year: 2003
Journal: J Biol Chem
Title: DNA damage-induced G2/M checkpoint in SV40 large T antigen-immortalized embryonic fibroblast cells requires SHP-2 tyrosine phosphatase.
Volume: 278
Issue: 44
Pages: 42812-20
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Publication
22576369 | J:241280
 
First Author: Sala V
Year: 2012
Journal: Mol Med
Title: Signaling to cardiac hypertrophy: insights from human and mouse RASopathies.
Volume: 18
Pages: 938-47
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11895767 | J:75835
First Author: Yu WM
Year: 2002
Journal: Blood
Title: Role of the docking protein Gab2 in beta(1)-integrin signaling pathway-mediated hematopoietic cell adhesion and migration.
Volume: 99
Issue: 7
Pages: 2351-9
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18827006 | J:140959
First Author: Mitra S
Year: 2008
Journal: J Cell Sci
Title: SHP-2 is a novel target of Abl kinases during cell proliferation.
Volume: 121
Issue: Pt 20
Pages: 3335-46
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17954568 | J:126125
First Author: Kong XN
Year: 2007
Journal: J Exp Med
Title: LPS-induced down-regulation of signal regulatory protein {alpha} contributes to innate immune activation in macrophages.
Volume: 204
Issue: 11
Pages: 2719-31
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11832424 | J:75523
First Author: Sorenson CM
Year: 2002
Journal: Am J Physiol Renal Physiol
Title: Altered regulation of SHP-2 and PTP 1B tyrosine phosphatases in cystic kidneys from bcl-2 -/- mice.
Volume: 282
Issue: 3
Pages: F442-50
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15677447 | J:98567
First Author: Novotny-Diermayr V
Year: 2005
Journal: J Biol Chem
Title: Modulation of the interleukin-6 receptor subunit glycoprotein 130 complex and its signaling by LMO4 interaction.
Volume: 280
Issue: 13
Pages: 12747-57
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11970986 | J:112147
First Author: Ott VL
Year: 2002
Journal: J Immunol
Title: Downstream of kinase, p62(dok), is a mediator of Fc gamma IIB inhibition of Fc epsilon RI signaling.
Volume: 168
Issue: 9
Pages: 4430-9
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19287004 | J:149742
First Author: Yu L
Year: 2009
Journal: J Biol Chem
Title: JAK2 and SHP2 reciprocally regulate tyrosine phosphorylation and stability of proapoptotic protein ASK1.
Volume: 284
Issue: 20
Pages: 13481-8
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19542364 | J:151510
First Author: Tsai CC
Year: 2009
Journal: J Immunol
Title: Glycogen synthase kinase-3beta facilitates IFN-gamma-induced STAT1 activation by regulating Src homology-2 domain-containing phosphatase 2.
Volume: 183
Issue: 2
Pages: 856-64
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Publication
19587381 | J:152228
First Author: Jack GD
Year: 2009
Journal: Blood
Title: M-CSF elevates c-Fos and phospho-C/EBPalpha(S21) via ERK whereas G-CSF stimulates SHP2 phosphorylation in marrow progenitors to contribute to myeloid lineage specification.
Volume: 114
Issue: 10
Pages: 2172-80
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Publication
20421975 | J:160140
First Author: Kim DJ
Year: 2010
Journal: PLoS One
Title: Protein tyrosine phosphatases, TC-PTP, SHP1, and SHP2, cooperate in rapid dephosphorylation of Stat3 in keratinocytes following UVB irradiation.
Volume: 5
Issue: 4
Pages: e10290
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Publication
20846526 | J:164659
First Author: Cha Y
Year: 2010
Journal: FEBS Lett
Title: SHP2 is a downstream target of ZAP70 to regulate JAK1/STAT3 and ERK signaling pathways in mouse embryonic stem cells.
Volume: 584
Issue: 19
Pages: 4241-6
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27861634 | J:251516
First Author: Yasui T
Year: 2016
Journal: PLoS One
Title: Molecular Characterization of Striated Muscle-Specific Gab1 Isoform as a Critical Signal Transducer for Neuregulin-1/ErbB Signaling in Cardiomyocytes.
Volume: 11
Issue: 11
Pages: e0166710
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17213291 | J:145327
First Author: Wilson TJ
Year: 2007
Journal: Blood
Title: FcRL6, a new ITIM-bearing receptor on cytolytic cells, is broadly expressed by lymphocytes following HIV-1 infection.
Volume: 109
Issue: 9
Pages: 3786-93
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24590274 | J:209628
First Author: Brouillard P
Year: 2014
Journal: J Clin Invest
Title: Genetics of lymphatic anomalies.
Volume: 124
Issue: 3
Pages: 898-904
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38924432 | J:350494
First Author: Perrin S
Year: 2024
Journal: Sci Transl Med
Title: MEK-SHP2 inhibition prevents tibial pseudarthrosis caused by NF1 loss in Schwann cells and skeletal stem/progenitor cells.
Volume: 16
Issue: 753
Pages: eadj1597
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Publication
24493648 | J:207470
First Author: Sheean ME
Year: 2014
Journal: Genes Dev
Title: Activation of MAPK overrides the termination of myelin growth and replaces Nrg1/ErbB3 signals during Schwann cell development and myelination.
Volume: 28
Issue: 3
Pages: 290-303
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15569927 | J:94724
First Author: Gotoh N
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Tyrosine phosphorylation sites on FRS2alpha responsible for Shp2 recruitment are critical for induction of lens and retina.
Volume: 101
Issue: 49
Pages: 17144-9
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22015719 | J:178713
First Author: Willecke R
Year: 2011
Journal: Dev Biol
Title: The tyrosine phosphatase Shp2 acts downstream of GDNF/Ret in branching morphogenesis of the developing mouse kidney.
Volume: 360
Issue: 2
Pages: 310-7
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16239343 | J:102930
First Author: Yamamoto S
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Essential role of Shp2-binding sites on FRS2alpha for corticogenesis and for FGF2-dependent proliferation of neural progenitor cells.
Volume: 102
Issue: 44
Pages: 15983-8
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23452850 | J:206901
First Author: Findlay GM
Year: 2013
Journal: Cell
Title: Interaction domains of Sos1/Grb2 are finely tuned for cooperative control of embryonic stem cell fate.
Volume: 152
Issue: 5
Pages: 1008-20
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12893283 | J:84951
First Author: Kumagai H
Year: 2003
Journal: Biochem Biophys Res Commun
Title: Identification and characterization of a new pair of immunoglobulin-like receptors LMIR1 and 2 derived from murine bone marrow-derived mast cells.
Volume: 307
Issue: 3
Pages: 719-29
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15062102 | J:90089
First Author: Ballif BA
Year: 2004
Journal: Curr Biol
Title: Activation of a Dab1/CrkL/C3G/Rap1 pathway in Reelin-stimulated neurons.
Volume: 14
Issue: 7
Pages: 606-10
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23321074 | J:198116
First Author: Lee KY
Year: 2013
Journal: Diabetes
Title: Lessons on conditional gene targeting in mouse adipose tissue.
Volume: 62
Issue: 3
Pages: 864-74
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28983104 | J:255705
First Author: Wang L
Year: 2017
Journal: Sci Rep
Title: SHP2 Regulates the Osteogenic Fate of Growth Plate Hypertrophic Chondrocytes.
Volume: 7
Issue: 1
Pages: 12699
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18077586 | J:130571
First Author: Pan Y
Year: 2008
Journal: Development
Title: Bud specific N-sulfation of heparan sulfate regulates Shp2-dependent FGF signaling during lacrimal gland induction.
Volume: 135
Issue: 2
Pages: 301-10
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17646384 | J:126547
First Author: Ke Y
Year: 2007
Journal: Mol Cell Biol
Title: Deletion of Shp2 in the brain leads to defective proliferation and differentiation in neural stem cells and early postnatal lethality.
Volume: 27
Issue: 19
Pages: 6706-17
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Publication
20648636 | J:168041
First Author: Zhu Y
Year: 2010
Journal: Glia
Title: Control of oligodendrocyte generation and proliferation by Shp2 protein tyrosine phosphatase.
Volume: 58
Issue: 12
Pages: 1407-14
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Publication
35260907 | J:324721
 
First Author: Fang Y
Year: 2022
Journal: J Cell Sci
Title: SIRT1 regulates cardiomyocyte alignment during maturation.
Volume: 135
Issue: 7
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Publication
12808090 | J:83953
First Author: Holgado-Madruga M
Year: 2003
Journal: Mol Cell Biol
Title: Gab1 is an integrator of cell death versus cell survival signals in oxidative stress.
Volume: 23
Issue: 13
Pages: 4471-84
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