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Search results 201 to 300 out of 367 for Rrm2

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Type Details Score
Publication
14667816 | J:87849
First Author: Wang HY
Year: 2004
Journal: Genomics
Title: Structural diversity and functional implications of the eukaryotic TDP gene family.
Volume: 83
Issue: 1
Pages: 130-9
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Publication
17932037 | J:129028
First Author: Abhyankar MM
Year: 2007
Journal: J Biol Chem
Title: A novel CpG-free vertebrate insulator silences the testis-specific SP-10 gene in somatic tissues: role for TDP-43 in insulator function.
Volume: 282
Issue: 50
Pages: 36143-54
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Publication
18305110 | J:137092
First Author: Winton MJ
Year: 2008
Journal: J Biol Chem
Title: Disturbance of nuclear and cytoplasmic TAR DNA-binding protein (TDP-43) induces disease-like redistribution, sequestration, and aggregate formation.
Volume: 283
Issue: 19
Pages: 13302-9
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Publication
18703504 | J:142560
First Author: Bose JK
Year: 2008
Journal: J Biol Chem
Title: TDP-43 overexpression enhances exon 7 inclusion during the survival of motor neuron pre-mRNA splicing.
Volume: 283
Issue: 43
Pages: 28852-9
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Publication
18957508 | J:145775
First Author: Ayala YM
Year: 2008
Journal: J Cell Sci
Title: Structural determinants of the cellular localization and shuttling of TDP-43.
Volume: 121
Issue: Pt 22
Pages: 3778-85
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Publication
19535326 | J:153454
First Author: Iguchi Y
Year: 2009
Journal: J Biol Chem
Title: TDP-43 depletion induces neuronal cell damage through dysregulation of Rho family GTPases.
Volume: 284
Issue: 33
Pages: 22059-66
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Publication
19782731 | J:156639
First Author: Sato T
Year: 2009
Journal: Neuroscience
Title: Axonal ligation induces transient redistribution of TDP-43 in brainstem motor neurons.
Volume: 164
Issue: 4
Pages: 1565-78
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Publication
21252238 | J:170608
First Author: Lalmansingh AS
Year: 2011
Journal: J Biol Chem
Title: TDP-43 is a transcriptional repressor: the testis-specific mouse acrv1 gene is a TDP-43 target in vivo.
Volume: 286
Issue: 13
Pages: 10970-82
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Publication
21358643 | J:172305
First Author: Polymenidou M
Year: 2011
Journal: Nat Neurosci
Title: Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43.
Volume: 14
Issue: 4
Pages: 459-68
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Publication
22193716 | J:181968
First Author: Cohen TJ
Year: 2012
Journal: EMBO J
Title: Redox signalling directly regulates TDP-43 via cysteine oxidation and disulphide cross-linking.
Volume: 31
Issue: 5
Pages: 1241-52
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Publication
22323604 | J:181992
First Author: Kawahara Y
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: TDP-43 promotes microRNA biogenesis as a component of the Drosha and Dicer complexes.
Volume: 109
Issue: 9
Pages: 3347-52
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Publication
22855830 | J:185946
First Author: Avendaño-Vázquez SE
Year: 2012
Journal: Genes Dev
Title: Autoregulation of TDP-43 mRNA levels involves interplay between transcription, splicing, and alternative polyA site selection.
Volume: 26
Issue: 15
Pages: 1679-84
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Publication
23575225 | J:198525
First Author: Zhang YJ
Year: 2013
Journal: Hum Mol Genet
Title: The dual functions of the extreme N-terminus of TDP-43 in regulating its biological activity and inclusion formation.
Volume: 22
Issue: 15
Pages: 3112-22
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Publication
23827948 | J:202253
First Author: Wang W
Year: 2013
Journal: Hum Mol Genet
Title: The ALS disease-associated mutant TDP-43 impairs mitochondrial dynamics and function in motor neurons.
Volume: 22
Issue: 23
Pages: 4706-19
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Publication
24381309 | J:209163
First Author: Yan S
Year: 2014
Journal: Hum Mol Genet
Title: TDP-43 causes differential pathology in neuronal versus glial cells in the mouse brain.
Volume: 23
Issue: 10
Pages: 2678-93
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Publication
24466128 | J:212560
First Author: D'Alton S
Year: 2014
Journal: PLoS One
Title: Divergent phenotypes in mutant TDP-43 transgenic mice highlight potential confounds in TDP-43 transgenic modeling.
Volume: 9
Issue: 1
Pages: e86513
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Publication
25557830 | J:219752
 
First Author: Lee S
Year: 2015
Journal: Nat Commun
Title: Identification of a subnuclear body involved in sequence-specific cytokine RNA processing.
Volume: 6
Pages: 5791
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Publication
29125873 | J:250916
First Author: Yahara M
Year: 2017
Journal: PLoS One
Title: U6 snRNA expression prevents toxicity in TDP-43-knockdown cells.
Volume: 12
Issue: 11
Pages: e0187813
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Publication
29142232 | J:256947
First Author: Herzog JJ
Year: 2017
Journal: Sci Rep
Title: TDP-43 misexpression causes defects in dendritic growth.
Volume: 7
Issue: 1
Pages: 15656
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Publication
29715546 | J:265750
 
First Author: Davis SA
Year: 2018
Journal: Neurosci Lett
Title: TDP-43 interacts with mitochondrial proteins critical for mitophagy and mitochondrial dynamics.
Volume: 678
Pages: 8-15
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Publication
22641816 | J:264883
First Author: Fallini C
Year: 2012
Journal: Hum Mol Genet
Title: The ALS disease protein TDP-43 is actively transported in motor neuron axons and regulates axon outgrowth.
Volume: 21
Issue: 16
Pages: 3703-18
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Publication
30853299 | J:277792
First Author: Gasset-Rosa F
Year: 2019
Journal: Neuron
Title: Cytoplasmic TDP-43 De-mixing Independent of Stress Granules Drives Inhibition of Nuclear Import, Loss of Nuclear TDP-43, and Cell Death.
Volume: 102
Issue: 2
Pages: 339-357.e7
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Publication
33398173 | J:305455
First Author: Zuo X
Year: 2021
Journal: Nat Struct Mol Biol
Title: TDP-43 aggregation induced by oxidative stress causes global mitochondrial imbalance in ALS.
Volume: 28
Issue: 2
Pages: 132-142
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Publication
23134510 | J:356718
First Author: Narayanan RK
Year: 2013
Journal: Amyotroph Lateral Scler Frontotemporal Degener
Title: Identification of RNA bound to the TDP-43 ribonucleoprotein complex in the adult mouse brain.
Volume: 14
Issue: 4
Pages: 252-60
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Publication
25678563 | J:292536
First Author: Lauranzano E
Year: 2015
Journal: Brain
Title: Peptidylprolyl isomerase A governs TARDBP function and assembly in heterogeneous nuclear ribonucleoprotein complexes.
Volume: 138
Issue: Pt 4
Pages: 974-91
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Publication
30464263 | J:268274
First Author: Vogler TO
Year: 2018
Journal: Nature
Title: TDP-43 and RNA form amyloid-like myo-granules in regenerating muscle.
Volume: 563
Issue: 7732
Pages: 508-513
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Publication
23175812 | J:192445
First Author: Pelletier S
Year: 2012
Journal: J Neurosci
Title: An early onset progressive motor neuron disorder in Scyl1-deficient mice is associated with mislocalization of TDP-43.
Volume: 32
Issue: 47
Pages: 16560-73
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Publication
37460529 | J:338266
First Author: Nie X
Year: 2023
Journal: Nat Commun
Title: Maternal TDP-43 interacts with RNA Pol II and regulates zygotic genome activation.
Volume: 14
Issue: 1
Pages: 4275
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Publication
34824257 | J:357597
First Author: Altman T
Year: 2021
Journal: Nat Commun
Title: Axonal TDP-43 condensates drive neuromuscular junction disruption through inhibition of local synthesis of nuclear encoded mitochondrial proteins.
Volume: 12
Issue: 1
Pages: 6914
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Publication
39305312 | J:357803
First Author: Torres P
Year: 2024
Journal: Acta Neuropathol
Title: TDP-43 regulates LC3ylation in neural tissue through ATG4B cryptic splicing inhibition.
Volume: 148
Issue: 1
Pages: 45
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Publication
20188146 | J:161495
First Author: Tudor EL
Year: 2010
Journal: Neuroscience
Title: Amyotrophic lateral sclerosis mutant vesicle-associated membrane protein-associated protein-B transgenic mice develop TAR-DNA-binding protein-43 pathology.
Volume: 167
Issue: 3
Pages: 774-85
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Publication
24120466 | J:206607
 
First Author: Haidet-Phillips AM
Year: 2013
Journal: Exp Neurol
Title: Altered astrocytic expression of TDP-43 does not influence motor neuron survival.
Volume: 250
Pages: 250-9
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Publication
28941811 | J:261236
First Author: Wiesner D
Year: 2018
Journal: Exp Neurol
Title: Reversible induction of TDP-43 granules in cortical neurons after traumatic injury.
Volume: 299
Issue: Pt A
Pages: 15-25
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Publication
33945510 | J:339810
 
First Author: Sanchez II
Year: 2021
Journal: J Clin Invest
Title: Huntington's disease mice and human brain tissue exhibit increased G3BP1 granules and TDP43 mislocalization.
Volume: 131
Issue: 12
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Publication
30373824 | J:267269
First Author: Wang J
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Cell-autonomous requirement of TDP-43, an ALS/FTD signature protein, for oligodendrocyte survival and myelination.
Volume: 115
Issue: 46
Pages: E10941-E10950
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Publication
34347016 | J:328367
 
First Author: Ho WY
Year: 2021
Journal: J Cell Biol
Title: TDP-43 mediates SREBF2-regulated gene expression required for oligodendrocyte myelination.
Volume: 220
Issue: 9
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Publication
32325033 | J:298772
First Author: Pourhaghighi R
Year: 2020
Journal: Cell Syst
Title: BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Volume: 10
Issue: 4
Pages: 333-350.e14
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Publication
35311646 | J:333154
   
First Author: Heo D
Year: 2022
Journal: Elife
Title: Stage-specific control of oligodendrocyte survival and morphogenesis by TDP-43.
Volume: 11
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Publication
28669544 | J:241917
First Author: Paolicelli RC
Year: 2017
Journal: Neuron
Title: TDP-43 Depletion in Microglia Promotes Amyloid Clearance but Also Induces Synapse Loss.
Volume: 95
Issue: 2
Pages: 297-308.e6
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Publication
38124145 | J:350853
First Author: Dogan EO
Year: 2023
Journal: Acta Neuropathol Commun
Title: Genetic ablation of Sarm1 attenuates expression and mislocalization of phosphorylated TDP-43 after mouse repetitive traumatic brain injury.
Volume: 11
Issue: 1
Pages: 206
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Publication
38287033 | J:351186
First Author: Kaye EG
Year: 2024
Journal: Nat Commun
Title: RNA polymerase II pausing is essential during spermatogenesis for appropriate gene expression and completion of meiosis.
Volume: 15
Issue: 1
Pages: 848
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Publication
24515116 | J:214706
First Author: Stribl C
Year: 2014
Journal: J Biol Chem
Title: Mitochondrial dysfunction and decrease in body weight of a transgenic knock-in mouse model for TDP-43.
Volume: 289
Issue: 15
Pages: 10769-84
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Publication
32187538 | J:287650
First Author: Sleigh JN
Year: 2020
Journal: Cell Rep
Title: Mice Carrying ALS Mutant TDP-43, but Not Mutant FUS, Display In Vivo Defects in Axonal Transport of Signaling Endosomes.
Volume: 30
Issue: 11
Pages: 3655-3662.e2
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Publication
32686835 | J:296433
First Author: Marques RF
Year: 2020
Journal: Hum Mol Genet
Title: Motor neuron translatome reveals deregulation of SYNGR4 and PLEKHB1 in mutant TDP-43 amyotrophic lateral sclerosis models.
Volume: 29
Issue: 16
Pages: 2647-2661
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Publication
38374041 | J:346667
First Author: San Gil R
Year: 2024
Journal: Nat Commun
Title: A transient protein folding response targets aggregation in the early phase of TDP-43-mediated neurodegeneration.
Volume: 15
Issue: 1
Pages: 1508
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Publication
38366598 | J:348663
First Author: Ke YD
Year: 2024
Journal: Neuron
Title: Targeting 14-3-3θ-mediated TDP-43 pathology in amyotrophic lateral sclerosis and frontotemporal dementia mice.
Volume: 112
Issue: 8
Pages: 1249-1264.e8
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Publication
30377984 | J:329603
First Author: Picher-Martel V
Year: 2019
Journal: Mol Neurobiol
Title: Neuronal Expression of UBQLN2P497H Exacerbates TDP-43 Pathology in TDP-43G348C Mice through Interaction with Ubiquitin.
Volume: 56
Issue: 7
Pages: 4680-4696
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Publication
33908654 | J:308816
First Author: Lin LT
Year: 2021
Journal: FASEB J
Title: Hsp90 and its co-chaperone Sti1 control TDP-43 misfolding and toxicity.
Volume: 35
Issue: 5
Pages: e21594
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Publication
24740308 | J:215201
First Author: Dib S
Year: 2014
Journal: PLoS One
Title: Gene targeting of mouse Tardbp negatively affects Masp2 expression.
Volume: 9
Issue: 4
Pages: e95373
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Publication
39603486 | J:360641
 
First Author: Krus KL
Year: 2025
Journal: Exp Neurol
Title: Two cardinal features of ALS, reduced STMN2 and pathogenic TDP-43, synergize to accelerate motor decline in mice.
Volume: 384
Pages: 115068
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Publication
22718532 | J:259127
First Author: Herskowitz JH
Year: 2012
Journal: Proteomics
Title: Asparaginyl endopeptidase cleaves TDP-43 in brain.
Volume: 12
Issue: 15-16
Pages: 2455-63
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Publication
28585542 | J:250353
 
First Author: Woo JA
Year: 2017
Journal: Nat Commun
Title: Loss of function CHCHD10 mutations in cytoplasmic TDP-43 accumulation and synaptic integrity.
Volume: 8
Pages: 15558
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Publication
23172908 | J:191202
First Author: Tauffenberger A
Year: 2013
Journal: Hum Mol Genet
Title: Reduction of polyglutamine toxicity by TDP-43, FUS and progranulin in Huntington's disease models.
Volume: 22
Issue: 4
Pages: 782-94
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Publication
23023293 | J:192741
First Author: Lagier-Tourenne C
Year: 2012
Journal: Nat Neurosci
Title: Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs.
Volume: 15
Issue: 11
Pages: 1488-97
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Publication
23022214 | J:192743
 
First Author: Scofield MD
Year: 2012
Journal: Neuroscience
Title: Nucleus Accumbens 1, a Pox virus and Zinc finger/Bric-a-brac Tramtrack Broad protein binds to TAR DNA-binding protein 43 and has a potential role in Amyotrophic Lateral Sclerosis.
Volume: 227
Pages: 44-54
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Publication
23236149 | J:193178
First Author: Prudencio M
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Misregulation of human sortilin splicing leads to the generation of a nonfunctional progranulin receptor.
Volume: 109
Issue: 52
Pages: 21510-5
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Publication
26130692 | J:225837
First Author: Chou CC
Year: 2015
Journal: Hum Mol Genet
Title: PABPN1 suppresses TDP-43 toxicity in ALS disease models.
Volume: 24
Issue: 18
Pages: 5154-73
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Publication
28724966 | J:248804
First Author: Wang P
Year: 2017
Journal: Nat Commun
Title: Acetylation-induced TDP-43 pathology is suppressed by an HSF1-dependent chaperone program.
Volume: 8
Issue: 1
Pages: 82
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Publication
29109149 | J:256056
First Author: Goh CW
Year: 2018
Journal: J Biol Chem
Title: Chronic oxidative stress promotes GADD34-mediated phosphorylation of the TAR DNA-binding protein TDP-43, a modification linked to neurodegeneration.
Volume: 293
Issue: 1
Pages: 163-176
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Publication
32907941 | J:296365
First Author: Liu W
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: LncRNA Malat1 inhibition of TDP43 cleavage suppresses IRF3-initiated antiviral innate immunity.
Volume: 117
Issue: 38
Pages: 23695-23706
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Publication
30404641 | J:319828
First Author: Lee YC
Year: 2018
Journal: J Biomed Sci
Title: Znf179 E3 ligase-mediated TDP-43 polyubiquitination is involved in TDP-43- ubiquitinated inclusions (UBI) (+)-related neurodegenerative pathology.
Volume: 25
Issue: 1
Pages: 76
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Publication
26936937 | J:318779
First Author: Chen HJ
Year: 2016
Journal: Brain
Title: The heat shock response plays an important role in TDP-43 clearance: evidence for dysfunction in amyotrophic lateral sclerosis.
Volume: 139
Issue: Pt 5
Pages: 1417-32
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Publication
29618024 | J:318521
First Author: Militello G
Year: 2018
Journal: J Mol Cell Biol
Title: A novel long non-coding RNA Myolinc regulates myogenesis through TDP-43 and Filip1.
Volume: 10
Issue: 2
Pages: 102-117
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Publication
11374897 | J:69922
First Author: Blanco P
Year: 2001
Journal: Genomics
Title: A novel poly(A)-binding protein gene (PABPC5) maps to an X-specific subinterval in the Xq21.3/Yp11.2 homology block of the human sex chromosomes.
Volume: 74
Issue: 1
Pages: 1-11
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Publication
11328870 | -
First Author: Féral C
Year: 2001
Journal: Nucleic Acids Res
Title: Human testis expresses a specific poly(A)-binding protein.
Volume: 29
Issue: 9
Pages: 1872-83
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Publication
15146077 | -
First Author: Will CL
Year: 2004
Journal: RNA
Title: The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome.
Volume: 10
Issue: 6
Pages: 929-41
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Publication
12844354 | -
First Author: Mangus DA
Year: 2003
Journal: Genome Biol
Title: Poly(A)-binding proteins: multifunctional scaffolds for the post-transcriptional control of gene expression.
Volume: 4
Issue: 7
Pages: 223
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10499800 | -
First Author: Deo RC
Year: 1999
Journal: Cell
Title: Recognition of polyadenylate RNA by the poly(A)-binding protein.
Volume: 98
Issue: 6
Pages: 835-45
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14717712 | -
First Author: Sladic RT
Year: 2004
Journal: Eur J Biochem
Title: Human PABP binds AU-rich RNA via RNA-binding domains 3 and 4.
Volume: 271
Issue: 2
Pages: 450-7
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Publication
26554031 | -
First Author: Kini HK
Year: 2016
Journal: RNA
Title: Cytoplasmic poly(A) binding protein-1 binds to genomically encoded sequences within mammalian mRNAs.
Volume: 22
Issue: 1
Pages: 61-74
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Publication
21940797 | J:183010
First Author: Burgess HM
Year: 2011
Journal: J Cell Sci
Title: Nuclear relocalisation of cytoplasmic poly(A)-binding proteins PABP1 and PABP4 in response to UV irradiation reveals mRNA-dependent export of metazoan PABPs.
Volume: 124
Issue: Pt 19
Pages: 3344-55
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Publication
9418852 | -
First Author: Kessler SH
Year: 1998
Journal: Mol Cell Biol
Title: RNA recognition motif 2 of yeast Pab1p is required for its functional interaction with eukaryotic translation initiation factor 4G.
Volume: 18
Issue: 1
Pages: 51-7
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Publication
29802307 | J:262555
First Author: Vogt MA
Year: 2018
Journal: Sci Rep
Title: TDP-43 induces p53-mediated cell death of cortical progenitors and immature neurons.
Volume: 8
Issue: 1
Pages: 8097
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Publication
28832631 | J:247223
First Author: Penndorf D
Year: 2017
Journal: PLoS One
Title: DNA strand breaks and TDP-43 mislocation are absent in the murine hSOD1G93A model of amyotrophic lateral sclerosis in vivo and in vitro.
Volume: 12
Issue: 8
Pages: e0183684
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Publication
35262486 | J:327262
   
First Author: Harb K
Year: 2022
Journal: Elife
Title: Pum2 and TDP-43 refine area-specific cytoarchitecture post-mitotically and modulate translation of Sox5, Bcl11b, and Rorb mRNAs in developing mouse neocortex.
Volume: 11
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Publication
31355778 | J:294122
First Author: Araki K
Year: 2019
Journal: J Clin Invest
Title: TDP-43 regulates early-phase insulin secretion via CaV1.2-mediated exocytosis in islets.
Volume: 129
Issue: 9
Pages: 3578-3593
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Publication
25457553 | J:219503
First Author: Liu Y
Year: 2015
Journal: Neurobiol Aging
Title: Changes in TDP-43 expression in development, aging, and in the neurofilament light protein knockout mouse.
Volume: 36
Issue: 2
Pages: 1151-9
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Publication
30410094 | J:278089
First Author: Vaughan SK
Year: 2018
Journal: Sci Rep
Title: The ALS-inducing factors, TDP43A315T and SOD1G93A, directly affect and sensitize sensory neurons to stress.
Volume: 8
Issue: 1
Pages: 16582
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Publication
24154542 | J:206221
First Author: Magrané J
Year: 2014
Journal: Hum Mol Genet
Title: Abnormal mitochondrial transport and morphology are common pathological denominators in SOD1 and TDP43 ALS mouse models.
Volume: 23
Issue: 6
Pages: 1413-24
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Publication
34112844 | J:323697
First Author: Mejia Maza A
Year: 2021
Journal: Sci Rep
Title: NMJ-Analyser identifies subtle early changes in mouse models of neuromuscular disease.
Volume: 11
Issue: 1
Pages: 12251
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Publication
22718760 | J:190254
First Author: Wu LS
Year: 2012
Journal: J Biol Chem
Title: Targeted depletion of TDP-43 expression in the spinal cord motor neurons leads to the development of amyotrophic lateral sclerosis-like phenotypes in mice.
Volume: 287
Issue: 33
Pages: 27335-44
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Publication
33689679 | J:303815
   
First Author: Chang KJ
Year: 2021
Journal: Elife
Title: TDP-43 maximizes nerve conduction velocity by repressing a cryptic exon for paranodal junction assembly in Schwann cells.
Volume: 10
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Publication
18238900 | J:131829
First Author: Kim HJ
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Liver X receptor beta (LXRbeta): a link between beta-sitosterol and amyotrophic lateral sclerosis-Parkinson's dementia.
Volume: 105
Issue: 6
Pages: 2094-9
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Publication
38585660 | J:348975
First Author: Zhang H
Year: 2024
Journal: iScience
Title: TDP-43 deficiency in suprachiasmatic nucleus perturbs rhythmicity of neuroactivity in prefrontal cortex.
Volume: 27
Issue: 4
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