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Search results 201 to 300 out of 538 for Snca

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Category: Publication
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Type Details Score
Publication
23626796 | J:200633
First Author: Bender A
Year: 2013
Journal: PLoS One
Title: TOM40 mediates mitochondrial dysfunction induced by α-synuclein accumulation in Parkinson's disease.
Volume: 8
Issue: 4
Pages: e62277
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Publication
12009758 | J:76482
First Author: Richfield EK
Year: 2002
Journal: Exp Neurol
Title: Behavioral and neurochemical effects of wild-type and mutated human alpha-synuclein in transgenic mice.
Volume: 175
Issue: 1
Pages: 35-48
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Publication
38351057 | J:352009
 
First Author: Keomanivong C
Year: 2024
Journal: eNeuro
Title: Mice Expressing A53T/A30P Mutant Alpha-Synuclein in Dopamine Neurons Do Not Display Behavioral Deficits.
Volume: 11
Issue: 2
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Publication
37981650 | J:354471
First Author: McFleder RL
Year: 2023
Journal: Nat Commun
Title: Brain-to-gut trafficking of alpha-synuclein by CD11c(+) cells in a mouse model of Parkinson's disease.
Volume: 14
Issue: 1
Pages: 7529
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Publication
15840579 | J:100267
First Author: Liu CW
Year: 2005
Journal: J Biol Chem
Title: A precipitating role for truncated alpha-synuclein and the proteasome in alpha-synuclein aggregation: implications for pathogenesis of Parkinson disease.
Volume: 280
Issue: 24
Pages: 22670-8
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Publication
15684072 | J:96471
First Author: Li W
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Aggregation promoting C-terminal truncation of alpha-synuclein is a normal cellular process and is enhanced by the familial Parkinson's disease-linked mutations.
Volume: 102
Issue: 6
Pages: 2162-7
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Publication
30249789 | J:267419
First Author: Teravskis PJ
Year: 2018
Journal: J Neurosci
Title: A53T Mutant Alpha-Synuclein Induces Tau-Dependent Postsynaptic Impairment Independently of Neurodegenerative Changes.
Volume: 38
Issue: 45
Pages: 9754-9767
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Publication
15743798 | J:96778
First Author: Stefanova N
Year: 2005
Journal: Am J Pathol
Title: Oxidative stress in transgenic mice with oligodendroglial alpha-synuclein overexpression replicates the characteristic neuropathology of multiple system atrophy.
Volume: 166
Issue: 3
Pages: 869-76
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Publication
30116778 | J:287434
First Author: Sumitomo A
Year: 2018
Journal: Sci Adv
Title: A mouse model of 22q11.2 deletions: Molecular and behavioral signatures of Parkinson's disease and schizophrenia.
Volume: 4
Issue: 8
Pages: eaar6637
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Publication
36167783 | J:353062
First Author: Kulkarni VV
Year: 2022
Journal: J Neurosci
Title: Retrograde Axonal Autophagy and Endocytic Pathways Are Parallel and Separate in Neurons.
Volume: 42
Issue: 45
Pages: 8524-8541
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Publication
19228951 | J:146833
First Author: Lu XH
Year: 2009
Journal: J Neurosci
Title: Bacterial artificial chromosome transgenic mice expressing a truncated mutant parkin exhibit age-dependent hypokinetic motor deficits, dopaminergic neuron degeneration, and accumulation of proteinase K-resistant alpha-synuclein.
Volume: 29
Issue: 7
Pages: 1962-76
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Publication
31346295 | J:279709
First Author: Henderson MX
Year: 2019
Journal: Nat Neurosci
Title: Spread of α-synuclein pathology through the brain connectome is modulated by selective vulnerability and predicted by network analysis.
Volume: 22
Issue: 8
Pages: 1248-1257
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Publication
31754648 | J:288696
 
First Author: Trubetckaia O
Year: 2019
Journal: Commun Biol
Title: Alpha-synuclein is strategically positioned for afferent modulation of midbrain dopamine neurons and is essential for cocaine preference.
Volume: 2
Pages: 418
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Publication
39426376 | J:358174
     
First Author: Matsuo K
Year: 2024
Journal: Cell
Title: RNA G-quadruplexes form scaffolds that promote neuropathological α-synuclein aggregation.
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Publication
28576704 | J:259157
 
First Author: Abdelmotilib H
Year: 2017
Journal: Neurobiol Dis
Title: α-Synuclein fibril-induced inclusion spread in rats and mice correlates with dopaminergic Neurodegeneration.
Volume: 105
Pages: 84-98
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Publication
34233191 | J:328722
First Author: Fonseca-Ornelas L
Year: 2021
Journal: Cell Rep
Title: Altered conformation of α-synuclein drives dysfunction of synaptic vesicles in a synaptosomal model of Parkinson's disease.
Volume: 36
Issue: 1
Pages: 109333
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Publication
30538177 | J:284406
 
First Author: Kim T
Year: 2018
Journal: Sci Signal
Title: The microRNA miR-7a-5p ameliorates ischemic brain damage by repressing α-synuclein.
Volume: 11
Issue: 560
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Publication
30308173 | J:268903
First Author: Nuber S
Year: 2018
Journal: Neuron
Title: Abrogating Native α-Synuclein Tetramers in Mice Causes a L-DOPA-Responsive Motor Syndrome Closely Resembling Parkinson's Disease.
Volume: 100
Issue: 1
Pages: 75-90.e5
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Publication
25009275 | J:353741
First Author: Games D
Year: 2014
Journal: J Neurosci
Title: Reducing C-terminal-truncated alpha-synuclein by immunotherapy attenuates neurodegeneration and propagation in Parkinson's disease-like models.
Volume: 34
Issue: 28
Pages: 9441-54
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Publication
25961568 | J:235336
First Author: Schreglmann SR
Year: 2015
Journal: PLoS One
Title: The temporal expression pattern of alpha-synuclein modulates olfactory neurogenesis in transgenic mice.
Volume: 10
Issue: 5
Pages: e0126261
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Publication
30509990 | J:269264
First Author: Yan R
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Synergistic neuroprotection by coffee components eicosanoyl-5-hydroxytryptamide and caffeine in models of Parkinson's disease and DLB.
Volume: 115
Issue: 51
Pages: E12053-E12062
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Publication
24746855 | J:214012
 
First Author: Savolainen MH
Year: 2014
Journal: Neurobiol Dis
Title: The beneficial effect of a prolyl oligopeptidase inhibitor, KYP-2047, on alpha-synuclein clearance and autophagy in A30P transgenic mouse.
Volume: 68
Pages: 1-15
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Publication
23643841 | J:197984
 
First Author: Hansen C
Year: 2013
Journal: Neurobiol Dis
Title: A novel α-synuclein-GFP mouse model displays progressive motor impairment, olfactory dysfunction and accumulation of α-synuclein-GFP.
Volume: 56
Pages: 145-55
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Publication
15797547 | J:99814
First Author: Yazawa I
Year: 2005
Journal: Neuron
Title: Mouse model of multiple system atrophy alpha-synuclein expression in oligodendrocytes causes glial and neuronal degeneration.
Volume: 45
Issue: 6
Pages: 847-59
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Publication
21966373 | J:177661
First Author: Rieker C
Year: 2011
Journal: PLoS One
Title: Neuropathology in mice expressing mouse alpha-synuclein.
Volume: 6
Issue: 9
Pages: e24834
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Publication
16291942 | J:102867
First Author: Shults CW
Year: 2005
Journal: J Neurosci
Title: Neurological and neurodegenerative alterations in a transgenic mouse model expressing human alpha-synuclein under oligodendrocyte promoter: implications for multiple system atrophy.
Volume: 25
Issue: 46
Pages: 10689-99
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Publication
15765523 | J:238692
First Author: Rockenstein E
Year: 2005
Journal: J Neurosci Res
Title: Lysosomal pathology associated with alpha-synuclein accumulation in transgenic models using an eGFP fusion protein.
Volume: 80
Issue: 2
Pages: 247-59
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Publication
32996158 | J:301897
First Author: Nuber S
Year: 2021
Journal: Ann Neurol
Title: A Stearoyl-Coenzyme A Desaturase Inhibitor Prevents Multiple Parkinson Disease Phenotypes in α-Synuclein Mice.
Volume: 89
Issue: 1
Pages: 74-90
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Publication
35179202 | J:351405
First Author: Geertsma HM
Year: 2022
Journal: Hum Mol Genet
Title: Constitutive nuclear accumulation of endogenous alpha-synuclein in mice causes motor impairment and cortical dysfunction, independent of protein aggregation.
Volume: 31
Issue: 21
Pages: 3613-3628
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Publication
10978144 | J:64149
First Author: Rochet JC
Year: 2000
Journal: Biochemistry
Title: Inhibition of fibrillization and accumulation of prefibrillar oligomers in mixtures of human and mouse alpha-synuclein.
Volume: 39
Issue: 35
Pages: 10619-26
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Publication
17475220 | J:122473
First Author: Nakai M
Year: 2007
Journal: Biochem Biophys Res Commun
Title: Expression of alpha-synuclein, a presynaptic protein implicated in Parkinson's disease, in erythropoietic lineage.
Volume: 358
Issue: 1
Pages: 104-10
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Publication
20106983 | J:165946
First Author: Doxakis E
Year: 2010
Journal: J Biol Chem
Title: Post-transcriptional regulation of alpha-synuclein expression by mir-7 and mir-153.
Volume: 285
Issue: 17
Pages: 12726-34
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Publication
16959795 | J:154831
First Author: Kontopoulos E
Year: 2006
Journal: Hum Mol Genet
Title: Alpha-synuclein acts in the nucleus to inhibit histone acetylation and promote neurotoxicity.
Volume: 15
Issue: 20
Pages: 3012-23
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Publication
21563316 | J:212791
First Author: Esposito G
Year: 2012
Journal: Dev Neurobiol
Title: Synaptic vesicle trafficking and Parkinson's disease.
Volume: 72
Issue: 1
Pages: 134-44
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Publication
21127069 | J:168706
First Author: Qureshi HY
Year: 2011
Journal: J Biol Chem
Title: Parkinsonian neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and alpha-synuclein mutations promote Tau protein phosphorylation at Ser262 and destabilize microtubule cytoskeleton in vitro.
Volume: 286
Issue: 7
Pages: 5055-68
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Publication
17222866 | J:212805
First Author: Volles MJ
Year: 2007
Journal: J Mol Biol
Title: Relationships between the sequence of alpha-synuclein and its membrane affinity, fibrillization propensity, and yeast toxicity.
Volume: 366
Issue: 5
Pages: 1510-22
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Publication
11113617 | J:66439
First Author: Sommer B
Year: 2000
Journal: Exp Gerontol
Title: Mouse models of alpha-synucleinopathy and Lewy pathology.
Volume: 35
Issue: 9-10
Pages: 1389-403
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Publication
10786830 | J:61686
First Author: Dawson TM
Year: 2000
Journal: Cell
Title: New animal models for Parkinson's disease.
Volume: 101
Issue: 2
Pages: 115-8
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Publication
10799001 | J:61769
First Author: Dawson VL
Year: 2000
Journal: Science
Title: Neurobiology. Of flies and mice.
Volume: 288
Issue: 5466
Pages: 631-2
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Publication
16242637 | J:102823
First Author: Yavich L
Year: 2005
Journal: Neurobiol Dis
Title: Locomotor activity and evoked dopamine release are reduced in mice overexpressing A30P-mutated human alpha-synuclein.
Volume: 20
Issue: 2
Pages: 303-13
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Publication
15639180 | J:115466
First Author: Siegmund A
Year: 2005
Journal: Behav Brain Res
Title: Differences in extinction of conditioned fear in C57BL/6 substrains are unrelated to expression of alpha-synuclein.
Volume: 157
Issue: 2
Pages: 291-8
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Publication
17108165 | J:116160
First Author: Larsen KE
Year: 2006
Journal: J Neurosci
Title: Alpha-synuclein overexpression in PC12 and chromaffin cells impairs catecholamine release by interfering with a late step in exocytosis.
Volume: 26
Issue: 46
Pages: 11915-22
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Publication
18172548 | J:131061
First Author: Martinez-Vicente M
Year: 2008
Journal: J Clin Invest
Title: Dopamine-modified alpha-synuclein blocks chaperone-mediated autophagy.
Volume: 118
Issue: 2
Pages: 777-88
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Publication
19286568 | J:147053
First Author: Nakayama K
Year: 2009
Journal: Am J Pathol
Title: Microtubule depolymerization suppresses alpha-synuclein accumulation in a mouse model of multiple system atrophy.
Volume: 174
Issue: 4
Pages: 1471-80
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Publication
18992718 | J:147817
 
First Author: Ikeda M
Year: 2009
Journal: Brain Res
Title: Motor impairment and aberrant production of neurochemicals in human alpha-synuclein A30P+A53T transgenic mice with alpha-synuclein pathology.
Volume: 1250
Pages: 232-41
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Publication
20485674 | J:160921
First Author: Unni VK
Year: 2010
Journal: PLoS One
Title: In vivo imaging of alpha-synuclein in mouse cortex demonstrates stable expression and differential subcellular compartment mobility.
Volume: 5
Issue: 5
Pages: e10589
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Publication
21055449 | J:170285
 
First Author: Kim YH
Year: 2011
Journal: Neuroscience
Title: Inducible dopaminergic glutathione depletion in an α-synuclein transgenic mouse model results in age-related olfactory dysfunction.
Volume: 172
Pages: 379-86
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Publication
20550572 | J:171788
First Author: Feng LR
Year: 2010
Journal: Eur J Neurosci
Title: Alpha-synuclein mediates alterations in membrane conductance: a potential role for alpha-synuclein oligomers in cell vulnerability.
Volume: 32
Issue: 1
Pages: 10-7
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Publication
21982369 | J:178534
First Author: Volpicelli-Daley LA
Year: 2011
Journal: Neuron
Title: Exogenous α-synuclein fibrils induce Lewy body pathology leading to synaptic dysfunction and neuron death.
Volume: 72
Issue: 1
Pages: 57-71
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Publication
21840348 | J:180897
First Author: Park SN
Year: 2011
Journal: Neurosci Res
Title: α-Synuclein deficiency and efferent nerve degeneration in the mouse cochlea: a possible cause of early-onset presbycusis.
Volume: 71
Issue: 3
Pages: 303-10
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Publication
22033456 | J:184032
 
First Author: Huang Z
Year: 2011
Journal: Neuroscience
Title: Determining nuclear localization of alpha-synuclein in mouse brains.
Volume: 199
Pages: 318-32
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Publication
23100443 | J:192170
First Author: Burré J
Year: 2012
Journal: J Neurosci
Title: Systematic mutagenesis of α-synuclein reveals distinct sequence requirements for physiological and pathological activities.
Volume: 32
Issue: 43
Pages: 15227-42
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Publication
24381286 | J:205588
First Author: Guardia-Laguarta C
Year: 2014
Journal: J Neurosci
Title: α-Synuclein is localized to mitochondria-associated ER membranes.
Volume: 34
Issue: 1
Pages: 249-59
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Publication
24058406 | J:206500
First Author: Gardai SJ
Year: 2013
Journal: PLoS One
Title: Elevated alpha-synuclein impairs innate immune cell function and provides a potential peripheral biomarker for Parkinson's disease.
Volume: 8
Issue: 8
Pages: e71634
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Publication
24382629 | J:207504
First Author: Reyes JF
Year: 2014
Journal: Glia
Title: Alpha-synuclein transfers from neurons to oligodendrocytes.
Volume: 62
Issue: 3
Pages: 387-98
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Publication
25471588 | J:218741
First Author: Aelvoet SA
Year: 2014
Journal: J Neurosci
Title: Noninvasive bioluminescence imaging of α-synuclein oligomerization in mouse brain using split firefly luciferase reporters.
Volume: 34
Issue: 49
Pages: 16518-32
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Publication
26076669 | J:223029
 
First Author: Dettmer U
Year: 2015
Journal: Nat Commun
Title: Parkinson-causing α-synuclein missense mutations shift native tetramers to monomers as a mechanism for disease initiation.
Volume: 6
Pages: 7314
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Publication
25428949 | J:228849
 
First Author: Tank J
Year: 2014
Journal: Physiol Rep
Title: Preserved functional autonomic phenotype in adult mice overexpressing moderate levels of human alpha-synuclein in oligodendrocytes.
Volume: 2
Issue: 11
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Publication
30219847 | J:268226
First Author: Pinho R
Year: 2019
Journal: Hum Mol Genet
Title: Nuclear localization and phosphorylation modulate pathological effects of alpha-synuclein.
Volume: 28
Issue: 1
Pages: 31-50
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Publication
31358782 | J:283944
First Author: Schaser AJ
Year: 2019
Journal: Sci Rep
Title: Alpha-synuclein is a DNA binding protein that modulates DNA repair with implications for Lewy body disorders.
Volume: 9
Issue: 1
Pages: 10919
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Publication
30796692 | J:295558
First Author: Yan DY
Year: 2019
Journal: Neurotox Res
Title: Mn-Induced Neurocytes Injury and Autophagy Dysfunction in Alpha-Synuclein Wild-Type and Knock-Out Mice: Highlighting the Role of Alpha-Synuclein.
Volume: 36
Issue: 1
Pages: 66-80
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Publication
32817196 | J:302434
 
First Author: Parajuli LK
Year: 2020
Journal: eNeuro
Title: Developmental Changes in Dendritic Spine Morphology in the Striatum and Their Alteration in an A53T α-Synuclein Transgenic Mouse Model of Parkinson's Disease.
Volume: 7
Issue: 4
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Publication
34121985 | J:343007
 
First Author: Li H
Year: 2021
Journal: Front Neurosci
Title: Dl-3-n-Butylphthalide Alleviates Behavioral and Cognitive Symptoms Via Modulating Mitochondrial Dynamics in the A53T-α-Synuclein Mouse Model of Parkinson's Disease.
Volume: 15
Pages: 647266
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Publication
25997379 | J:314575
First Author: Seleem AA
Year: 2015
Journal: Tissue Cell
Title: Expression of alpha-synuclein during eye development of mice (Mus musculus), chick (Gallus gallus domisticus) and fish (Ctenopharyngodon idella) in a comparison study.
Volume: 47
Issue: 4
Pages: 359-65
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Publication
24252179 | J:319040
 
First Author: Kim S
Year: 2014
Journal: Exp Neurol
Title: Alpha-synuclein interferes with cAMP/PKA-dependent upregulation of dopamine β-hydroxylase and is associated with abnormal adaptive responses to immobilization stress.
Volume: 252
Pages: 63-74
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Publication
22779732 | J:318096
First Author: Wang L
Year: 2012
Journal: Neurogastroenterol Motil
Title: Mice overexpressing wild-type human alpha-synuclein display alterations in colonic myenteric ganglia and defecation.
Volume: 24
Issue: 9
Pages: e425-36
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Publication
37434423 | J:342662
First Author: Muhammad B
Year: 2023
Journal: J Neurochem
Title: IL-1β/IL-1R1 signaling is involved in the propagation of α-synuclein pathology of the gastrointestinal tract to the brain.
Volume: 166
Issue: 5
Pages: 830-846
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Publication
19004816 | J:147239
First Author: Inglis KJ
Year: 2009
Journal: J Biol Chem
Title: Polo-like kinase 2 (PLK2) phosphorylates alpha-synuclein at serine 129 in central nervous system.
Volume: 284
Issue: 5
Pages: 2598-602
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Publication
10707987 | J:60151
First Author: Abeliovich A
Year: 2000
Journal: Neuron
Title: Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system.
Volume: 25
Issue: 1
Pages: 239-52
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Publication
24415155 | J:208051
First Author: Smith BR
Year: 2014
Journal: J Pathol
Title: Neuronal inclusions of α-synuclein contribute to the pathogenesis of Krabbe disease.
Volume: 232
Issue: 5
Pages: 509-21
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Publication
29718367 | J:321148
First Author: Scudamore O
Year: 2018
Journal: J Neuropathol Exp Neurol
Title: Increased Oxidative Stress Exacerbates α-Synuclein Aggregation In Vivo.
Volume: 77
Issue: 6
Pages: 443-453
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Publication
21801874 | J:174596
First Author: Stefanova N
Year: 2011
Journal: Am J Pathol
Title: Toll-like receptor 4 promotes α-synuclein clearance and survival of nigral dopaminergic neurons.
Volume: 179
Issue: 2
Pages: 954-63
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Publication
28462393 | J:255900
 
First Author: Pathak D
Year: 2017
Journal: eNeuro
Title: Loss of α-Synuclein Does Not Affect Mitochondrial Bioenergetics in Rodent Neurons.
Volume: 4
Issue: 2
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19097673 | J:159589
First Author: Al-Wandi A
Year: 2010
Journal: Neurobiol Aging
Title: Absence of alpha-synuclein affects dopamine metabolism and synaptic markers in the striatum of aging mice.
Volume: 31
Issue: 5
Pages: 796-804
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15784963 | J:121324
First Author: Papachroni K
Year: 2005
Journal: J Mol Neurosci
Title: Peripheral sensory neurons survive in the absence of alpha- and gamma-synucleins.
Volume: 25
Issue: 2
Pages: 157-64
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Publication
27021360 | J:321445
 
First Author: Tarasova TV
Year: 2016
Journal: Dokl Biol Sci
Title: The role of alpha-synuclein in the development of the dopaminergic neurons in the substantia nigra and ventral tegmental area.
Volume: 466
Pages: 5-7
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Publication
20079841 | J:159933
First Author: Cano-Jaimez M
Year: 2010
Journal: Neurobiol Dis
Title: Vulnerability of peripheral catecholaminergic neurons to MPTP is not regulated by alpha-synuclein.
Volume: 38
Issue: 1
Pages: 92-103
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Publication
28533388 | J:242277
First Author: Larson ME
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Selective lowering of synapsins induced by oligomeric α-synuclein exacerbates memory deficits.
Volume: 114
Issue: 23
Pages: E4648-E4657
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Publication
18333965 | J:132938
First Author: Senior SL
Year: 2008
Journal: Eur J Neurosci
Title: Increased striatal dopamine release and hyperdopaminergic-like behaviour in mice lacking both alpha-synuclein and gamma-synuclein.
Volume: 27
Issue: 4
Pages: 947-57
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Publication
23349488 | J:208568
First Author: Steneberg P
Year: 2013
Journal: Diabetes
Title: The type 2 diabetes-associated gene ide is required for insulin secretion and suppression of α-synuclein levels in β-cells.
Volume: 62
Issue: 6
Pages: 2004-14
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Publication
29759483 | J:276192
 
First Author: Ugras S
Year: 2018
Journal: EBioMedicine
Title: Induction of the Immunoproteasome Subunit Lmp7 Links Proteostasis and Immunity in α-Synuclein Aggregation Disorders.
Volume: 31
Pages: 307-319
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Publication
27708076 | J:235638
 
First Author: Mao X
Year: 2016
Journal: Science
Title: Pathological α-synuclein transmission initiated by binding lymphocyte-activation gene 3.
Volume: 353
Issue: 6307
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Publication
32356558 | J:295385
First Author: Pan PY
Year: 2020
Journal: Hum Mol Genet
Title: Synj1 haploinsufficiency causes dopamine neuron vulnerability and alpha-synuclein accumulation in mice.
Volume: 29
Issue: 14
Pages: 2300-2312
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