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Search results 201 to 300 out of 374 for Sqstm1

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Type Details Score
Publication
22167182 | J:181513
First Author: Lee J
Year: 2012
Journal: J Biol Chem
Title: Autophagy suppresses interleukin-1β (IL-1β) signaling by activation of p62 degradation via lysosomal and proteasomal pathways.
Volume: 287
Issue: 6
Pages: 4033-40
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Publication
21041446 | J:166712
First Author: Riley BE
Year: 2010
Journal: J Cell Biol
Title: Ubiquitin accumulation in autophagy-deficient mice is dependent on the Nrf2-mediated stress response pathway: a potential role for protein aggregation in autophagic substrate selection.
Volume: 191
Issue: 3
Pages: 537-52
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Publication
21317241 | J:169446
First Author: Guo JY
Year: 2011
Journal: Genes Dev
Title: Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis.
Volume: 25
Issue: 5
Pages: 460-70
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Publication
34400288 | J:313600
 
First Author: Liu Y
Year: 2021
Journal: Neurosci Lett
Title: GSK-3 mediates nuclear translocation of p62/SQSTM1 in MPTP-induced mouse model of Parkinson's disease.
Volume: 763
Pages: 136177
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Publication
27436578 | J:233299
First Author: Kamaludin AA
Year: 2016
Journal: Hum Mol Genet
Title: Muscle dysfunction caused by loss of Magel2 in a mouse model of Prader-Willi and Schaaf-Yang syndromes.
Volume: 25
Issue: 17
Pages: 3798-3809
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Publication
20616007 | J:162412
First Author: Whitehouse CA
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Neighbor of Brca1 gene (Nbr1) functions as a negative regulator of postnatal osteoblastic bone formation and p38 MAPK activity.
Volume: 107
Issue: 29
Pages: 12913-8
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Publication
29764981 | J:265666
 
First Author: Fratta P
Year: 2018
Journal: EMBO J
Title: Mice with endogenous TDP-43 mutations exhibit gain of splicing function and characteristics of amyotrophic lateral sclerosis.
Volume: 37
Issue: 11
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Publication
26440898 | J:312451
First Author: Lee Y
Year: 2015
Journal: Cell Rep
Title: p62 Plays a Specific Role in Interferon-γ-Induced Presentation of a Toxoplasma Vacuolar Antigen.
Volume: 13
Issue: 2
Pages: 223-33
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Publication
17389358 | J:120306
First Author: Zhou X
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Unc-51-like kinase 1/2-mediated endocytic processes regulate filopodia extension and branching of sensory axons.
Volume: 104
Issue: 14
Pages: 5842-7
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Publication
21757726 | J:176619
First Author: Traver MK
Year: 2011
Journal: J Biol Chem
Title: Immunity-related GTPase M (IRGM) proteins influence the localization of guanylate-binding protein 2 (GBP2) by modulating macroautophagy.
Volume: 286
Issue: 35
Pages: 30471-80
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Publication
19201866 | J:144793
First Author: Kim JY
Year: 2009
Journal: J Immunol
Title: The sequestosome 1/p62 attenuates cytokine gene expression in activated macrophages by inhibiting IFN regulatory factor 8 and TNF receptor-associated factor 6/NF-kappaB activity.
Volume: 182
Issue: 4
Pages: 2131-40
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Publication
23754749 | J:204564
First Author: Guo L
Year: 2013
Journal: Mol Cell Biol
Title: Transactivation of Atg4b by C/EBPβ promotes autophagy to facilitate adipogenesis.
Volume: 33
Issue: 16
Pages: 3180-90
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Publication
25605500 | J:221369
First Author: Martins-Marques T
Year: 2015
Journal: Biochem J
Title: Ischaemia-induced autophagy leads to degradation of gap junction protein connexin43 in cardiomyocytes.
Volume: 467
Issue: 2
Pages: 231-45
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Publication
22049074 | J:302619
First Author: Nishimura I
Year: 2011
Journal: J Biol Chem
Title: RB1CC1 protein suppresses type II collagen synthesis in chondrocytes and causes dwarfism.
Volume: 286
Issue: 51
Pages: 43925-43932
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Publication
39841822 | J:361258
First Author: Eibach Y
Year: 2025
Journal: Sci Adv
Title: The deubiquitinase USP5 prevents accumulation of protein aggregates in cardiomyocytes.
Volume: 11
Issue: 4
Pages: eado3852
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20577052 | J:163712
First Author: Mariño G
Year: 2010
Journal: J Clin Invest
Title: Autophagy is essential for mouse sense of balance.
Volume: 120
Issue: 7
Pages: 2331-44
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23954414 | J:203842
First Author: He C
Year: 2013
Journal: Cell
Title: Beclin 2 functions in autophagy, degradation of G protein-coupled receptors, and metabolism.
Volume: 154
Issue: 5
Pages: 1085-99
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24011591 | J:203811
First Author: Ichimura Y
Year: 2013
Journal: Mol Cell
Title: Phosphorylation of p62 activates the Keap1-Nrf2 pathway during selective autophagy.
Volume: 51
Issue: 5
Pages: 618-31
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Publication
30704899 | J:272052
First Author: Cheng X
Year: 2019
Journal: Mol Cell
Title: Pacer Is a Mediator of mTORC1 and GSK3-TIP60 Signaling in Regulation of Autophagosome Maturation and Lipid Metabolism.
Volume: 73
Issue: 4
Pages: 788-802.e7
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Publication
23274085 | J:195093
First Author: Bae SH
Year: 2013
Journal: Cell Metab
Title: Sestrins activate Nrf2 by promoting p62-dependent autophagic degradation of Keap1 and prevent oxidative liver damage.
Volume: 17
Issue: 1
Pages: 73-84
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Publication
18083104 | J:130839
First Author: Komatsu M
Year: 2007
Journal: Cell
Title: Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice.
Volume: 131
Issue: 6
Pages: 1149-63
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Publication
26682926 | J:233172
First Author: Mehanna S
Year: 2016
Journal: Biochem Biophys Res Commun
Title: Cathepsin D in pancreatic acinar cells is implicated in cathepsin B and L degradation, but not in autophagic activity.
Volume: 469
Issue: 3
Pages: 405-11
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Publication
23479732 | J:198392
First Author: Morishita H
Year: 2013
Journal: J Biol Chem
Title: Deletion of autophagy-related 5 (Atg5) and Pik3c3 genes in the lens causes cataract independent of programmed organelle degradation.
Volume: 288
Issue: 16
Pages: 11436-47
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Publication
18346206 | J:137273
First Author: Ramesh Babu J
Year: 2008
Journal: J Neurochem
Title: Genetic inactivation of p62 leads to accumulation of hyperphosphorylated tau and neurodegeneration.
Volume: 106
Issue: 1
Pages: 107-20
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Publication
33296658 | J:300057
First Author: Morishita H
Year: 2020
Journal: Cell Rep
Title: Autophagy Is Required for Maturation of Surfactant-Containing Lamellar Bodies in the Lung and Swim Bladder.
Volume: 33
Issue: 10
Pages: 108477
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Publication
26649827 | J:228300
First Author: Kimmey JM
Year: 2015
Journal: Nature
Title: Unique role for ATG5 in neutrophil-mediated immunopathology during M. tuberculosis infection.
Volume: 528
Issue: 7583
Pages: 565-9
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Publication
31142229 | J:284681
First Author: Ivankovic D
Year: 2020
Journal: Autophagy
Title: Axonal autophagosome maturation defect through failure of ATG9A sorting underpins pathology in AP-4 deficiency syndrome.
Volume: 16
Issue: 3
Pages: 391-407
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Publication
28513333 | J:269844
First Author: Yamaguchi J
Year: 2018
Journal: Autophagy
Title: Atg9a deficiency causes axon-specific lesions including neuronal circuit dysgenesis.
Volume: 14
Issue: 5
Pages: 764-777
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Publication
24954904 | J:215480
First Author: Dooley HC
Year: 2014
Journal: Mol Cell
Title: WIPI2 links LC3 conjugation with PI3P, autophagosome formation, and pathogen clearance by recruiting Atg12-5-16L1.
Volume: 55
Issue: 2
Pages: 238-52
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Publication
16702235 | J:111284
First Author: Weinert S
Year: 2006
Journal: J Cell Biol
Title: M line-deficient titin causes cardiac lethality through impaired maturation of the sarcomere.
Volume: 173
Issue: 4
Pages: 559-70
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Publication
22792322 | J:189648
First Author: Fusco C
Year: 2012
Journal: PLoS One
Title: The E3-ubiquitin ligase TRIM50 interacts with HDAC6 and p62, and promotes the sequestration and clearance of ubiquitinated proteins into the aggresome.
Volume: 7
Issue: 7
Pages: e40440
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Publication
25198012 | J:225200
 
First Author: Orosco LA
Year: 2014
Journal: Nat Commun
Title: Loss of Wdfy3 in mice alters cerebral cortical neurogenesis reflecting aspects of the autism pathology.
Volume: 5
Pages: 4692
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Publication
24035364 | J:208209
First Author: Bonilla DL
Year: 2013
Journal: Immunity
Title: Autophagy regulates phagocytosis by modulating the expression of scavenger receptors.
Volume: 39
Issue: 3
Pages: 537-47
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Publication
26764600 | J:281303
First Author: Lu Q
Year: 2016
Journal: Cell Host Microbe
Title: Homeostatic Control of Innate Lung Inflammation by Vici Syndrome Gene Epg5 and Additional Autophagy Genes Promotes Influenza Pathogenesis.
Volume: 19
Issue: 1
Pages: 102-13
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Publication
29775594 | J:262835
First Author: Ke FFS
Year: 2018
Journal: Cell
Title: Embryogenesis and Adult Life in the Absence of Intrinsic Apoptosis Effectors BAX, BAK, and BOK.
Volume: 173
Issue: 5
Pages: 1217-1230.e17
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28386022 | J:251846
First Author: Ross JA
Year: 2017
Journal: J Cell Sci
Title: Multiple roles of integrin-α3 at the neuromuscular junction.
Volume: 130
Issue: 10
Pages: 1772-1784
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Publication
35593053 | J:330579
First Author: Gambarotto L
Year: 2022
Journal: J Cachexia Sarcopenia Muscle
Title: Ambra1 deficiency impairs mitophagy in skeletal muscle.
Volume: 13
Issue: 4
Pages: 2211-2224
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Publication
28137967 | J:239593
First Author: Zhang ZH
Year: 2017
Journal: J Neurosci
Title: Selenomethionine Mitigates Cognitive Decline by Targeting Both Tau Hyperphosphorylation and Autophagic Clearance in an Alzheimer's Disease Mouse Model.
Volume: 37
Issue: 9
Pages: 2449-2462
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Publication
26764599 | J:302622
First Author: Park S
Year: 2016
Journal: Cell Host Microbe
Title: Autophagy Genes Enhance Murine Gammaherpesvirus 68 Reactivation from Latency by Preventing Virus-Induced Systemic Inflammation.
Volume: 19
Issue: 1
Pages: 91-101
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Publication
31754024 | J:282431
First Author: Minis A
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: The proteasome regulator PI31 is required for protein homeostasis, synapse maintenance, and neuronal survival in mice.
Volume: 116
Issue: 49
Pages: 24639-24650
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Publication
31223056 | J:306853
First Author: Feng Q
Year: 2020
Journal: Autophagy
Title: MAPT/Tau accumulation represses autophagy flux by disrupting IST1-regulated ESCRT-III complex formation: a vicious cycle in Alzheimer neurodegeneration.
Volume: 16
Issue: 4
Pages: 641-658
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Publication
35850054 | J:327503
 
First Author: Xu Z
Year: 2022
Journal: Int Immunopharmacol
Title: Card9 protects fungal peritonitis through regulating Malt1-mediated activation of autophagy in macrophage.
Volume: 110
Pages: 108941
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Publication
33742095 | J:305082
First Author: Pathak P
Year: 2021
Journal: Commun Biol
Title: Myopathy associated LDB3 mutation causes Z-disc disassembly and protein aggregation through PKCα and TSC2-mTOR downregulation.
Volume: 4
Issue: 1
Pages: 355
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Publication
21220506 | J:167845
First Author: Itakura E
Year: 2011
Journal: J Cell Biol
Title: p62 Targeting to the autophagosome formation site requires self-oligomerization but not LC3 binding.
Volume: 192
Issue: 1
Pages: 17-27
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Publication
39245708 | J:354208
First Author: Dong MZ
Year: 2024
Journal: Cell Death Dis
Title: Protein phosphatase 4 maintains the survival of primordial follicles by regulating autophagy in oocytes.
Volume: 15
Issue: 9
Pages: 658
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Publication
28396396 | J:242134
First Author: Zhao Z
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Formation of neurodegenerative aggresome and death-inducing signaling complex in maternal diabetes-induced neural tube defects.
Volume: 114
Issue: 17
Pages: 4489-4494
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32876528 | J:310981
First Author: González-Rodríguez P
Year: 2021
Journal: Autophagy
Title: The DNA methyltransferase DNMT3A contributes to autophagy long-term memory.
Volume: 17
Issue: 5
Pages: 1259-1277
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Publication
36167966 | J:329326
First Author: Marta C
Year: 2022
Journal: Sci Rep
Title: Mitochondrial function and intracellular distribution is severely affected in in vitro cultured mouse embryos.
Volume: 12
Issue: 1
Pages: 16152
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21551061 | J:172364
First Author: Kim BH
Year: 2011
Journal: Science
Title: A family of IFN-γ-inducible 65-kD GTPases protects against bacterial infection.
Volume: 332
Issue: 6030
Pages: 717-21
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27418600 | J:235148
First Author: Anderson DM
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Severe muscle wasting and denervation in mice lacking the RNA-binding protein ZFP106.
Volume: 113
Issue: 31
Pages: E4494-503
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32313051 | J:287101
First Author: Park S
Year: 2020
Journal: Nat Commun
Title: The endoplasmic reticulum stress-autophagy pathway controls hypothalamic development and energy balance regulation in leptin-deficient neonates.
Volume: 11
Issue: 1
Pages: 1914
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26235979 | J:225886
First Author: de Iriarte Rodríguez R
Year: 2015
Journal: Hear Res
Title: Age-regulated function of autophagy in the mouse inner ear.
Volume: 330
Issue: Pt A
Pages: 39-50
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34108486 | J:307971
First Author: De Risi M
Year: 2021
Journal: Nat Commun
Title: Altered heparan sulfate metabolism during development triggers dopamine-dependent autistic-behaviours in models of lysosomal storage disorders.
Volume: 12
Issue: 1
Pages: 3495
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26905199 | J:301660
First Author: Li M
Year: 2016
Journal: Stem Cell Reports
Title: EVA1A/TMEM166 Regulates Embryonic Neurogenesis by Autophagy.
Volume: 6
Issue: 3
Pages: 396-410
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23542691 | J:197614
First Author: Wang C
Year: 2013
Journal: Nat Neurosci
Title: FIP200 is required for maintenance and differentiation of postnatal neural stem cells.
Volume: 16
Issue: 5
Pages: 532-42
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37998373 | J:342871
 
First Author: Xiang J
Year: 2023
Journal: Cells
Title: ATF4 May Be Essential for Adaption of the Ocular Lens to Its Avascular Environment.
Volume: 12
Issue: 22
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29158485 | J:256230
First Author: Shin SW
Year: 2017
Journal: Nat Commun
Title: Cytoplasmic cleavage of DPPA3 is required for intracellular trafficking and cleavage-stage development in mice.
Volume: 8
Issue: 1
Pages: 1643
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33966596 | J:317416
First Author: Liu J
Year: 2021
Journal: Autophagy
Title: CREG1 promotes lysosomal biogenesis and function.
Volume: 17
Issue: 12
Pages: 4249-4265
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34048907 | J:307395
 
First Author: Mirra S
Year: 2021
Journal: Neurobiol Dis
Title: CERKL, a retinal dystrophy gene, regulates mitochondrial function and dynamics in the mammalian retina.
Volume: 156
Pages: 105405
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29719249 | J:270838
First Author: Wiederstein JL
Year: 2018
Journal: Cell Rep
Title: Skeletal Muscle-Specific Methyltransferase METTL21C Trimethylates p97 and Regulates Autophagy-Associated Protein Breakdown.
Volume: 23
Issue: 5
Pages: 1342-1356
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28413018 | J:240526
First Author: Hall EA
Year: 2017
Journal: Am J Hum Genet
Title: PLAA Mutations Cause a Lethal Infantile Epileptic Encephalopathy by Disrupting Ubiquitin-Mediated Endolysosomal Degradation of Synaptic Proteins.
Volume: 100
Issue: 5
Pages: 706-724
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30985297 | J:296116
First Author: Hirose T
Year: 2019
Journal: J Clin Invest
Title: ATP6AP2 variant impairs CNS development and neuronal survival to cause fulminant neurodegeneration.
Volume: 129
Issue: 5
Pages: 2145-2162
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22854957 | J:186307
First Author: Peng C
Year: 2012
Journal: J Biol Chem
Title: Ablation of vacuole protein sorting 18 (Vps18) gene leads to neurodegeneration and impaired neuronal migration by disrupting multiple vesicle transport pathways to lysosomes.
Volume: 287
Issue: 39
Pages: 32861-73
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26115514 | J:221937
First Author: Watson JA
Year: 2015
Journal: PLoS Genet
Title: Motor and Sensory Deficits in the teetering Mice Result from Mutation of the ESCRT Component HGS.
Volume: 11
Issue: 6
Pages: e1005290
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38505613 | J:346373
First Author: Liu B
Year: 2024
Journal: Theranostics
Title: NPC1 is required for postnatal islet β cell differentiation by maintaining mitochondria turnover.
Volume: 14
Issue: 5
Pages: 2058-2074
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26595272 | J:228212
First Author: Cinque L
Year: 2015
Journal: Nature
Title: FGF signalling regulates bone growth through autophagy.
Volume: 528
Issue: 7581
Pages: 272-5
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29311744 | J:258027
First Author: Gstrein T
Year: 2018
Journal: Nat Neurosci
Title: Mutations in Vps15 perturb neuronal migration in mice and are associated with neurodevelopmental disease in humans.
Volume: 21
Issue: 2
Pages: 207-217
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26222436 | J:228828
First Author: Hamazaki J
Year: 2015
Journal: PLoS Genet
Title: Redundant Roles of Rpn10 and Rpn13 in Recognition of Ubiquitinated Proteins and Cellular Homeostasis.
Volume: 11
Issue: 7
Pages: e1005401
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26383973 | J:239805
First Author: Grigaravicius P
Year: 2016
Journal: Cell Death Differ
Title: Rint1 inactivation triggers genomic instability, ER stress and autophagy inhibition in the brain.
Volume: 23
Issue: 3
Pages: 454-68
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36899856 | J:334092
 
First Author: Broadway-Stringer S
Year: 2023
Journal: Cells
Title: Insights into the Role of a Cardiomyopathy-Causing Genetic Variant in ACTN2.
Volume: 12
Issue: 5
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31059511 | J:275030
First Author: Ferder IC
Year: 2019
Journal: PLoS Genet
Title: Meiotic gatekeeper STRA8 suppresses autophagy by repressing Nr1d1 expression during spermatogenesis in mice.
Volume: 15
Issue: 5
Pages: e1008084
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Publication
30081710 | J:306954
First Author: Zecchini S
Year: 2019
Journal: Autophagy
Title: Autophagy controls neonatal myogenesis by regulating the GH-IGF1 system through a NFE2L2- and DDIT3-mediated mechanism.
Volume: 15
Issue: 1
Pages: 58-77
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Publication
37812701 | J:342544
First Author: Radzishevsky I
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: Impairment of serine transport across the blood-brain barrier by deletion of Slc38a5 causes developmental delay and motor dysfunction.
Volume: 120
Issue: 42
Pages: e2302780120
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30428088 | J:285853
First Author: Zhang S
Year: 2019
Journal: Cardiovasc Res
Title: WD40 repeat and FYVE domain containing 3 is essential for cardiac development.
Volume: 115
Issue: 8
Pages: 1320-1331
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32744119 | J:303303
   
First Author: Pan M
Year: 2020
Journal: Autophagy
Title: Mice deficient in UXT exhibit retinitis pigmentosa-like features via aberrant autophagy activation.
Pages: 1-16
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Publication
28380258 | J:309653
First Author: Tong Y
Year: 2017
Journal: FEBS Lett
Title: An essential role of intestinal cell kinase in lung development is linked to the perinatal lethality of human ECO syndrome.
Volume: 591
Issue: 9
Pages: 1247-1257
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36198274 | J:329967
First Author: Li H
Year: 2022
Journal: Cell Rep
Title: Destabilization of TP53 by USP10 is essential for neonatal autophagy and survival.
Volume: 41
Issue: 1
Pages: 111435
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Publication
38218976 | J:344311
First Author: Yan W
Year: 2024
Journal: Commun Biol
Title: Loss of Mptx2 alters bacteria composition and intestinal homeostasis potentially by impairing autophagy.
Volume: 7
Issue: 1
Pages: 94
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Publication
27383629 | J:316639
 
First Author: He MY
Year: 2016
Journal: Open Biol
Title: Nrf2 signalling and autophagy are involved in diabetes mellitus-induced defects in the development of mouse placenta.
Volume: 6
Issue: 7
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29078390 | J:249035
First Author: Kannan M
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: WD40-repeat 47, a microtubule-associated protein, is essential for brain development and autophagy.
Volume: 114
Issue: 44
Pages: E9308-E9317
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Publication
29180572 | J:253982
 
First Author: Norlin S
Year: 2018
Journal: Development
Title: The ATPase activity of Asna1/TRC40 is required for pancreatic progenitor cell survival.
Volume: 145
Issue: 1
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Publication
33436499 | J:308926
 
First Author: Yang J
Year: 2021
Journal: Sci Signal
Title: Augmented BMP signaling commits cranial neural crest cells to a chondrogenic fate by suppressing autophagic β-catenin degradation.
Volume: 14
Issue: 665
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Publication
22904094 | J:212629
First Author: Papanicolaou KN
Year: 2012
Journal: Circ Res
Title: Mitofusins 1 and 2 are essential for postnatal metabolic remodeling in heart.
Volume: 111
Issue: 8
Pages: 1012-26
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Publication
37353485 | J:337474
First Author: Cobo I
Year: 2023
Journal: Nat Commun
Title: NFIC regulates ribosomal biology and ER stress in pancreatic acinar cells and restrains PDAC initiation.
Volume: 14
Issue: 1
Pages: 3761
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Publication
25915474 | J:222854
First Author: Laguna A
Year: 2015
Journal: Nat Neurosci
Title: Dopaminergic control of autophagic-lysosomal function implicates Lmx1b in Parkinson's disease.
Volume: 18
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