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Search results 201 to 300 out of 348 for Vhl

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Category: Publication
Type Details Score
Publication
First Author: Ohh M
Year: 1998
Journal: Mol Cell
Title: The von Hippel-Lindau tumor suppressor protein is required for proper assembly of an extracellular fibronectin matrix.
Volume: 1
Issue: 7
Pages: 959-68
Publication
First Author: Lolkema MP
Year: 2007
Journal: FEBS Lett
Title: The von Hippel-Lindau tumour suppressor interacts with microtubules through kinesin-2.
Volume: 581
Issue: 24
Pages: 4571-6
Publication
First Author: Street VA
Year: 1998
Journal: Nat Genet
Title: Mutations in a plasma membrane Ca2+-ATPase gene cause deafness in deafwaddler mice.
Volume: 19
Issue: 4
Pages: 390-4
Publication  
First Author: Triner D
Year: 2017
Journal: Mol Cell Biol
Title: Epithelial Hypoxia-Inducible Factor 2α Facilitates the Progression of Colon Tumors through Recruiting Neutrophils.
Volume: 37
Issue: 5
Publication
First Author: Romeo SG
Year: 2019
Journal: Nat Cell Biol
Title: Endothelial proteolytic activity and interaction with non-resorbing osteoclasts mediate bone elongation.
Volume: 21
Issue: 4
Pages: 430-441
Publication
First Author: Liu Y
Year: 2006
Journal: Blood
Title: Suppression of Fas-FasL coexpression by erythropoietin mediates erythroblast expansion during the erythropoietic stress response in vivo.
Volume: 108
Issue: 1
Pages: 123-33
Publication
First Author: Aarup A
Year: 2016
Journal: Arterioscler Thromb Vasc Biol
Title: Hypoxia-Inducible Factor-1α Expression in Macrophages Promotes Development of Atherosclerosis.
Volume: 36
Issue: 9
Pages: 1782-90
Publication
First Author: Okabe K
Year: 2014
Journal: Cell
Title: Neurons limit angiogenesis by titrating VEGF in retina.
Volume: 159
Issue: 3
Pages: 584-96
Publication
First Author: Fachi JL
Year: 2019
Journal: Cell Rep
Title: Butyrate Protects Mice from Clostridium difficile-Induced Colitis through an HIF-1-Dependent Mechanism.
Volume: 27
Issue: 3
Pages: 750-761.e7
Publication
First Author: Ting KKY
Year: 2023
Journal: J Immunol
Title: Oxidized Low-Density Lipoprotein Accumulation Suppresses Glycolysis and Attenuates the Macrophage Inflammatory Response by Diverting Transcription from the HIF-1α to the Nrf2 Pathway.
Volume: 211
Issue: 10
Pages: 1561-1577
Publication
First Author: Ting KKY
Year: 2024
Journal: Sci Rep
Title: Cholesterol accumulation impairs HIF-1α-dependent immunometabolic reprogramming of LPS-stimulated macrophages by upregulating the NRF2 pathway.
Volume: 14
Issue: 1
Pages: 11162
Publication
First Author: Kobayashi H
Year: 2012
Journal: J Immunol
Title: Myeloid cell-derived hypoxia-inducible factor attenuates inflammation in unilateral ureteral obstruction-induced kidney injury.
Volume: 188
Issue: 10
Pages: 5106-15
Publication
First Author: Krishnan J
Year: 2009
Journal: Cell Metab
Title: Activation of a HIF1alpha-PPARgamma axis underlies the integration of glycolytic and lipid anabolic pathways in pathologic cardiac hypertrophy.
Volume: 9
Issue: 6
Pages: 512-24
Publication
First Author: Xue X
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Quantitative proteomics identifies STEAP4 as a critical regulator of mitochondrial dysfunction linking inflammation and colon cancer.
Volume: 114
Issue: 45
Pages: E9608-E9617
Publication
First Author: Ma X
Year: 2017
Journal: J Biol Chem
Title: Hypoxia-inducible factor 2α (HIF-2α) promotes colon cancer growth by potentiating Yes-associated protein 1 (YAP1) activity.
Volume: 292
Issue: 41
Pages: 17046-17056
Publication
First Author: Voss AK
Year: 2000
Journal: Development
Title: Mice lacking HSP90beta fail to develop a placental labyrinth.
Volume: 127
Issue: 1
Pages: 1-11
Publication
First Author: Kullmann JA
Year: 2020
Journal: Neuron
Title: Oxygen Tension and the VHL-Hif1α Pathway Determine Onset of Neuronal Polarization and Cerebellar Germinal Zone Exit.
Volume: 106
Issue: 4
Pages: 607-623.e5
Publication
First Author: Weidemann A
Year: 2010
Journal: Glia
Title: Astrocyte hypoxic response is essential for pathological but not developmental angiogenesis of the retina.
Volume: 58
Issue: 10
Pages: 1177-85
Publication
First Author: Weidemann A
Year: 2009
Journal: J Clin Invest
Title: The glial cell response is an essential component of hypoxia-induced erythropoiesis in mice.
Volume: 119
Issue: 11
Pages: 3373-83
Publication    
First Author: Kurihara T
Year: 2016
Journal: Elife
Title: Hypoxia-induced metabolic stress in retinal pigment epithelial cells is sufficient to induce photoreceptor degeneration.
Volume: 5
Publication
First Author: Zhang S
Year: 2020
Journal: Nat Commun
Title: Glial type specific regulation of CNS angiogenesis by HIFα-activated different signaling pathways.
Volume: 11
Issue: 1
Pages: 2027
Publication
First Author: Kim JW
Year: 2012
Journal: Cancer Res
Title: Loss of fibroblast HIF-1α accelerates tumorigenesis.
Volume: 72
Issue: 13
Pages: 3187-95
Publication
First Author: Biju MP
Year: 2004
Journal: Mol Cell Biol
Title: Vhlh gene deletion induces Hif-1-mediated cell death in thymocytes.
Volume: 24
Issue: 20
Pages: 9038-47
Publication
First Author: Labrousse-Arias D
Year: 2016
Journal: Cardiovasc Res
Title: HIF-2α-mediated induction of pulmonary thrombospondin-1 contributes to hypoxia-driven vascular remodelling and vasoconstriction.
Volume: 109
Issue: 1
Pages: 115-30
Publication
First Author: Rankin EB
Year: 2007
Journal: J Clin Invest
Title: Hypoxia-inducible factor-2 (HIF-2) regulates hepatic erythropoietin in vivo.
Volume: 117
Issue: 4
Pages: 1068-77
Publication
First Author: Farsijani NM
Year: 2016
Journal: J Clin Invest
Title: Renal epithelium regulates erythropoiesis via HIF-dependent suppression of erythropoietin.
Volume: 126
Issue: 4
Pages: 1425-37
Publication  
First Author: Wang X
Year: 2022
Journal: J Clin Invest
Title: A mitofusin 2/HIF1α axis sets a maturation checkpoint in regenerating skeletal muscle.
Volume: 132
Issue: 23
Publication
First Author: Ramakrishnan SK
Year: 2016
Journal: Cell Metab
Title: HIF2α Is an Essential Molecular Brake for Postprandial Hepatic Glucagon Response Independent of Insulin Signaling.
Volume: 23
Issue: 3
Pages: 505-16
Publication
First Author: Ramakrishnan SK
Year: 2014
Journal: Mol Cell Biol
Title: Loss of von Hippel-Lindau protein (VHL) increases systemic cholesterol levels through targeting hypoxia-inducible factor 2α and regulation of bile acid homeostasis.
Volume: 34
Issue: 7
Pages: 1208-20
Publication
First Author: Cho SH
Year: 2016
Journal: Nature
Title: Germinal centre hypoxia and regulation of antibody qualities by a hypoxia response system.
Volume: 537
Issue: 7619
Pages: 234-238
Publication
First Author: Usui Y
Year: 2015
Journal: J Clin Invest
Title: Neurovascular crosstalk between interneurons and capillaries is required for vision.
Volume: 125
Issue: 6
Pages: 2335-46
Publication
First Author: Bouaziz W
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Interaction of HIF1α and β-catenin inhibits matrix metalloproteinase 13 expression and prevents cartilage damage in mice.
Volume: 113
Issue: 19
Pages: 5453-8
Publication
First Author: Liu Q
Year: 2012
Journal: J Clin Invest
Title: Hypoxia-inducible factor regulates hepcidin via erythropoietin-induced erythropoiesis.
Volume: 122
Issue: 12
Pages: 4635-44
Publication
First Author: Xie L
Year: 2014
Journal: Mol Cell Biol
Title: Hypoxia-inducible factor/MAZ-dependent induction of caveolin-1 regulates colon permeability through suppression of occludin, leading to hypoxia-induced inflammation.
Volume: 34
Issue: 16
Pages: 3013-23
Publication
First Author: Rankin EB
Year: 2012
Journal: Cell
Title: The HIF signaling pathway in osteoblasts directly modulates erythropoiesis through the production of EPO.
Volume: 149
Issue: 1
Pages: 63-74
Publication
First Author: Anderson ER
Year: 2012
Journal: Mol Cell Biol
Title: The hypoxia-inducible factor-C/EBPα axis controls ethanol-mediated hepcidin repression.
Volume: 32
Issue: 19
Pages: 4068-77
Publication
First Author: Elorza A
Year: 2012
Journal: Mol Cell
Title: HIF2α acts as an mTORC1 activator through the amino acid carrier SLC7A5.
Volume: 48
Issue: 5
Pages: 681-91
Publication
First Author: Koulnis M
Year: 2012
Journal: Blood
Title: Contrasting dynamic responses in vivo of the Bcl-xL and Bim erythropoietic survival pathways.
Volume: 119
Issue: 5
Pages: 1228-39
Publication
First Author: Aro E
Year: 2012
Journal: J Biol Chem
Title: Hypoxia-inducible factor-1 (HIF-1) but not HIF-2 is essential for hypoxic induction of collagen prolyl 4-hydroxylases in primary newborn mouse epiphyseal growth plate chondrocytes.
Volume: 287
Issue: 44
Pages: 37134-44
Publication
First Author: Harada Y
Year: 2022
Journal: iScience
Title: Intracellular metabolic adaptation of intraepithelial CD4+CD8αα+ T lymphocytes.
Volume: 25
Issue: 4
Pages: 104021
Publication
First Author: Zhang S
Year: 2021
Journal: J Neurosci
Title: HIFα Regulates Developmental Myelination Independent of Autocrine Wnt Signaling.
Volume: 41
Issue: 2
Pages: 251-268
Publication
First Author: Walter KM
Year: 2014
Journal: Cell Metab
Title: Hif-2α promotes degradation of mammalian peroxisomes by selective autophagy.
Volume: 20
Issue: 5
Pages: 882-97
Publication
First Author: Taylor M
Year: 2011
Journal: Gastroenterology
Title: Hypoxia-inducible factor-2α mediates the adaptive increase of intestinal ferroportin during iron deficiency in mice.
Volume: 140
Issue: 7
Pages: 2044-55
Publication
First Author: Minamishima YA
Year: 2010
Journal: Science
Title: Reactivation of hepatic EPO synthesis in mice after PHD loss.
Volume: 329
Issue: 5990
Pages: 407
Publication
First Author: Albers J
Year: 2015
Journal: J Clin Invest
Title: A versatile modular vector system for rapid combinatorial mammalian genetics.
Volume: 125
Issue: 4
Pages: 1603-19
Publication
First Author: Lee SH
Year: 2012
Journal: J Biol Chem
Title: Runx2 protein stabilizes hypoxia-inducible factor-1α through competition with von Hippel-Lindau protein (pVHL) and stimulates angiogenesis in growth plate hypertrophic chondrocytes.
Volume: 287
Issue: 18
Pages: 14760-71
Publication
First Author: Urrutia AA
Year: 2016
Journal: Blood
Title: Prolyl-4-hydroxylase 2 and 3 coregulate murine erythropoietin in brain pericytes.
Volume: 128
Issue: 21
Pages: 2550-2560
Publication
First Author: Cheng J
Year: 2007
Journal: Cell
Title: SUMO-specific protease 1 is essential for stabilization of HIF1alpha during hypoxia.
Volume: 131
Issue: 3
Pages: 584-95
Publication
First Author: Zhang N
Year: 2010
Journal: Cell Metab
Title: The asparaginyl hydroxylase factor inhibiting HIF-1alpha is an essential regulator of metabolism.
Volume: 11
Issue: 5
Pages: 364-78
Publication
First Author: Segura I
Year: 2016
Journal: Cell Rep
Title: The Oxygen Sensor PHD2 Controls Dendritic Spines and Synapses via Modification of Filamin A.
Volume: 14
Issue: 11
Pages: 2653-67
Publication
First Author: Ghebranious N
Year: 1998
Journal: Oncogene
Title: Mouse models in tumor suppression.
Volume: 17
Issue: 25
Pages: 3385-400
Publication
First Author: Zhu X
Year: 2014
Journal: PLoS Genet
Title: A gain-of-function mutation in Tnni2 impeded bone development through increasing Hif3a expression in DA2B mice.
Volume: 10
Issue: 10
Pages: e1004589
Publication
First Author: Lumayag S
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration.
Volume: 110
Issue: 6
Pages: E507-16
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniPathway vocabulary mapping
Publication
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
Publication
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication        
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication    
First Author: Zhu W
Year: 2017
Journal: Elife
Title: Daam2 driven degradation of VHL promotes gliomagenesis.
Volume: 6
Publication
First Author: Tarade D
Year: 2018
Journal: Oncogene
Title: The HIF and other quandaries in VHL disease.
Volume: 37
Issue: 2
Pages: 139-147
Publication
First Author: Haase VH
Year: 2009
Journal: Curr Pharm Des
Title: The VHL tumor suppressor: master regulator of HIF.
Volume: 15
Issue: 33
Pages: 3895-903
Publication
First Author: Kim WY
Year: 2004
Journal: J Clin Oncol
Title: Role of VHL gene mutation in human cancer.
Volume: 22
Issue: 24
Pages: 4991-5004
Publication
First Author: Kaelin WG Jr
Year: 2009
Journal: Cancer
Title: Treatment of kidney cancer: insights provided by the VHL tumor-suppressor protein.
Volume: 115
Issue: 10 Suppl
Pages: 2262-72
Publication
First Author: Khacho M
Year: 2009
Journal: Future Oncol
Title: Subcellular dynamics of the VHL tumor suppressor: on the move for HIF degradation.
Volume: 5
Issue: 1
Pages: 85-95
Publication
First Author: Rathmell WK
Year: 2008
Journal: Expert Rev Anticancer Ther
Title: VHL inactivation in renal cell carcinoma: implications for diagnosis, prognosis and treatment.
Volume: 8
Issue: 1
Pages: 63-73
Publication
First Author: Russell RC
Year: 2007
Journal: Cell Cycle
Title: The role of VHL in the regulation of E-cadherin: a new connection in an old pathway.
Volume: 6
Issue: 1
Pages: 56-9
Publication
First Author: Clark PE
Year: 2009
Journal: Kidney Int
Title: The role of VHL in clear-cell renal cell carcinoma and its relation to targeted therapy.
Volume: 76
Issue: 9
Pages: 939-45
Publication
First Author: Kamura T
Year: 1999
Journal: Science
Title: Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase.
Volume: 284
Issue: 5414
Pages: 657-61
Publication
First Author: Zhang J
Year: 2018
Journal: Science
Title: VHL substrate transcription factor ZHX2 as an oncogenic driver in clear cell renal cell carcinoma.
Volume: 361
Issue: 6399
Pages: 290-295
Publication
First Author: Li S
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: EglN3 hydroxylase stabilizes BIM-EL linking VHL type 2C mutations to pheochromocytoma pathogenesis and chemotherapy resistance.
Volume: 116
Issue: 34
Pages: 16997-17006
Publication
First Author: Cowey CL
Year: 2009
Journal: Curr Oncol Rep
Title: VHL gene mutations in renal cell carcinoma: role as a biomarker of disease outcome and drug efficacy.
Volume: 11
Issue: 2
Pages: 94-101
Publication
First Author: Xiao Y
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: The m6A RNA demethylase FTO is a HIF-independent synthetic lethal partner with the VHL tumor suppressor.
Volume: 117
Issue: 35
Pages: 21441-21449
Publication
First Author: Chakraborty AA
Year: 2020
Journal: Semin Cancer Biol
Title: Coalescing lessons from oxygen sensing, tumor metabolism, and epigenetics to target VHL loss in kidney cancer.
Volume: 67
Issue: Pt 2
Pages: 34-42
Publication  
First Author: Kaelin WG Jr
Year: 2007
Journal: Methods Enzymol
Title: The von hippel-lindau tumor suppressor protein: an update.
Volume: 435
Pages: 371-83