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Search results 2001 to 2100 out of 2728 for Lepr

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Category: Publication
Type Details Score
Publication
First Author: Zhang B
Year: 1996
Journal: J Biol Chem
Title: Down-regulation of the expression of the obese gene by an antidiabetic thiazolidinedione in Zucker diabetic fatty rats and db/db mice.
Volume: 271
Issue: 16
Pages: 9455-9
Publication
First Author: Lynn RB
Year: 1996
Journal: Biochem Biophys Res Commun
Title: Autoradiographic localization of leptin binding in the choroid plexus of ob/ob and db/db mice.
Volume: 219
Issue: 3
Pages: 884-9
Publication
First Author: Devos R
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: OB protein binds specifically to the choroid plexus of mice and rats.
Volume: 93
Issue: 11
Pages: 5668-73
Publication
First Author: Igel M
Year: 1996
Journal: Diabetologia
Title: Long-term and rapid regulation of ob mRNA levels in adipose tissue from normal (Sprague Dawley rats) and obese (db/db mice, fa/fa rats) rodents.
Volume: 39
Issue: 7
Pages: 758-65
Publication
First Author: Hamann A
Year: 1996
Journal: Exp Clin Endocrinol Diabetes
Title: Regulation of energy balance by leptin.
Volume: 104
Issue: 4
Pages: 293-300
Publication
First Author: Spiegelman BM
Year: 1996
Journal: Cell
Title: Adipogenesis and obesity: rounding out the big picture.
Volume: 87
Issue: 3
Pages: 377-89
Publication
First Author: Hoggard N
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Leptin and leptin receptor mRNA and protein expression in the murine fetus and placenta.
Volume: 94
Issue: 20
Pages: 11073-8
Publication
First Author: Zhang Y
Year: 1997
Journal: Biochem Biophys Res Commun
Title: The leptin receptor mediates apparent autocrine regulation of leptin gene expression.
Volume: 240
Issue: 2
Pages: 492-5
Publication  
First Author: Mercer JG
Year: 1998
Journal: Regul Pept
Title: Association of leptin receptor (OB-Rb), NPY and GLP-1 gene expression in the ovine and murine brainstem.
Volume: 75-76
Pages: 271-8
Publication
First Author: Yamamoto Y
Year: 1999
Journal: Brain Res Mol Brain Res
Title: Down regulation of the prepro-orexin gene expression in genetically obese mice.
Volume: 65
Issue: 1
Pages: 14-22
Publication
First Author: Tonra JR
Year: 1999
Journal: Diabetes
Title: Brain-derived neurotrophic factor improves blood glucose control and alleviates fasting hyperglycemia in C57BLKS-Lepr(db)/lepr(db) mice.
Volume: 48
Issue: 3
Pages: 588-94
Publication
First Author: Ahima RS
Year: 1999
Journal: Endocrinology
Title: Regulation of neuronal and glial proteins by leptin: implications for brain development.
Volume: 140
Issue: 6
Pages: 2755-62
Publication
First Author: Gustavsson N
Year: 2006
Journal: J Endocrinol
Title: Cell specificity of the cytoplasmic Ca2+ response to tolbutamide is impaired in beta-cells from hyperglycemic mice.
Volume: 190
Issue: 2
Pages: 461-70
Publication
First Author: Yamanaka M
Year: 2006
Journal: Metabolism
Title: Protective effect of brain-derived neurotrophic factor on pancreatic islets in obese diabetic mice.
Volume: 55
Issue: 10
Pages: 1286-92
Publication
First Author: Tang CH
Year: 2007
Journal: J Immunol
Title: Leptin-induced IL-6 production is mediated by leptin receptor, insulin receptor substrate-1, phosphatidylinositol 3-kinase, Akt, NF-kappaB, and p300 pathway in microglia.
Volume: 179
Issue: 2
Pages: 1292-302
Publication
First Author: Feldman DE
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Pluripotency factor-mediated expression of the leptin receptor (OB-R) links obesity to oncogenesis through tumor-initiating stem cells.
Volume: 109
Issue: 3
Pages: 829-34
Publication
First Author: Verkerke H
Year: 2014
Journal: PLoS One
Title: Kinetics of leptin binding to the Q223R leptin receptor.
Volume: 9
Issue: 4
Pages: e94843
Publication
First Author: Xu T
Year: 2017
Journal: Biochem Biophys Res Commun
Title: Leptin/OB-R signaling is elevated in mice with Sjögren's syndrome and is implicated in disease pathogenesis.
Volume: 482
Issue: 4
Pages: 835-842
Publication  
First Author: Barnes TM
Year: 2020
Journal: Mol Metab
Title: Identification of the leptin receptor sequences crucial for the STAT3-Independent control of metabolism.
Volume: 32
Pages: 168-175
Publication
First Author: Chen J
Year: 2024
Journal: Diabetologia
Title: ACSF2 and lysine lactylation contribute to renal tubule injury in diabetes.
Volume: 67
Issue: 7
Pages: 1429-1443
Publication  
First Author: Surwit RS
Year: 1994
Journal: Mouse Genome
Title: Diet-induced obesity and diabetes in C57BL/6J and C57BL/KsJ mice
Volume: 92
Pages: 523-8
Publication      
First Author: Coleman DL
Year: 1982
Title: Spontaneous diabetes and obesity in rodents
Pages: 283-93
Publication  
First Author: Friedman JM
Year: 1988
Journal: Mouse News Lett
Title: Molecular mapping of the mouse ob and db genes.
Volume: 82
Pages: 110
Publication
First Author: Koo SH
Year: 2005
Journal: Nature
Title: The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism.
Volume: 437
Issue: 7062
Pages: 1109-11
Publication
First Author: Esterházy D
Year: 2011
Journal: Cell Metab
Title: Bace2 is a β cell-enriched protease that regulates pancreatic β cell function and mass.
Volume: 14
Issue: 3
Pages: 365-77
Publication
First Author: Desai U
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Lipid-lowering effects of anti-angiopoietin-like 4 antibody recapitulate the lipid phenotype found in angiopoietin-like 4 knockout mice.
Volume: 104
Issue: 28
Pages: 11766-71
Publication
First Author: Yang Y
Year: 2020
Journal: Biochem Biophys Res Commun
Title: LASS2 regulates hepatocyte steatosis by interacting with NDUFS2/OXPHOS related proteins.
Volume: 526
Issue: 4
Pages: 871-879
Publication
First Author: Gao X
Year: 2008
Journal: Am J Physiol Heart Circ Physiol
Title: AGE/RAGE produces endothelial dysfunction in coronary arterioles in type 2 diabetic mice.
Volume: 295
Issue: 2
Pages: H491-8
Publication
First Author: Nakae J
Year: 2012
Journal: EMBO J
Title: Novel repressor regulates insulin sensitivity through interaction with Foxo1.
Volume: 31
Issue: 10
Pages: 2275-95
Publication
First Author: Jager J
Year: 2010
Journal: Diabetes
Title: Tpl2 kinase is upregulated in adipose tissue in obesity and may mediate interleukin-1beta and tumor necrosis factor-{alpha} effects on extracellular signal-regulated kinase activation and lipolysis.
Volume: 59
Issue: 1
Pages: 61-70
Publication
First Author: Kraus D
Year: 2014
Journal: Nature
Title: Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity.
Volume: 508
Issue: 7495
Pages: 258-62
Publication
First Author: Ghilardi N
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: Defective STAT signaling by the leptin receptor in diabetic mice.
Volume: 93
Issue: 13
Pages: 6231-5
Publication
First Author: Bates SH
Year: 2003
Journal: Nature
Title: STAT3 signalling is required for leptin regulation of energy balance but not reproduction.
Volume: 421
Issue: 6925
Pages: 856-9
Publication
First Author: Gropler MC
Year: 2009
Journal: J Biol Chem
Title: Lipin 2 is a liver-enriched phosphatidate phosphohydrolase enzyme that is dynamically regulated by fasting and obesity in mice.
Volume: 284
Issue: 11
Pages: 6763-72
Publication
First Author: Bailleul B
Year: 1997
Journal: Nucleic Acids Res
Title: The leptin receptor promoter controls expression of a second distinct protein.
Volume: 25
Issue: 14
Pages: 2752-8
Publication
First Author: Duerrschmid C
Year: 2017
Journal: Nat Med
Title: Asprosin is a centrally acting orexigenic hormone.
Volume: 23
Issue: 12
Pages: 1444-1453
Publication
First Author: Zhou B
Year: 2014
Journal: Hepatology
Title: CLOCK/BMAL1 regulates circadian change of mouse hepatic insulin sensitivity by SIRT1.
Volume: 59
Issue: 6
Pages: 2196-206
Publication
First Author: Dentin R
Year: 2007
Journal: Nature
Title: Insulin modulates gluconeogenesis by inhibition of the coactivator TORC2.
Volume: 449
Issue: 7160
Pages: 366-9
Publication
First Author: Kharitonenkov A
Year: 2005
Journal: J Clin Invest
Title: FGF-21 as a novel metabolic regulator.
Volume: 115
Issue: 6
Pages: 1627-35
Publication
First Author: Toffoli B
Year: 2018
Journal: Am J Physiol Renal Physiol
Title: Hemicentin 1 influences podocyte dynamic changes in glomerular diseases.
Volume: 314
Issue: 6
Pages: F1154-F1165
Publication
First Author: Vieira E
Year: 2012
Journal: Endocrinology
Title: The clock gene Rev-erbα regulates pancreatic β-cell function: modulation by leptin and high-fat diet.
Volume: 153
Issue: 2
Pages: 592-601
Publication
First Author: Dominy JE Jr
Year: 2012
Journal: Mol Cell
Title: The deacetylase Sirt6 activates the acetyltransferase GCN5 and suppresses hepatic gluconeogenesis.
Volume: 48
Issue: 6
Pages: 900-13
Publication
First Author: Gimeno RE
Year: 1997
Journal: Diabetes
Title: Cloning and characterization of an uncoupling protein homolog: a potential molecular mediator of human thermogenesis.
Volume: 46
Issue: 5
Pages: 900-6
Publication
First Author: Koh A
Year: 2013
Journal: Mol Cell Biol
Title: C1-Ten is a protein tyrosine phosphatase of insulin receptor substrate 1 (IRS-1), regulating IRS-1 stability and muscle atrophy.
Volume: 33
Issue: 8
Pages: 1608-20
Publication
First Author: Du K
Year: 2003
Journal: Science
Title: TRB3: a tribbles homolog that inhibits Akt/PKB activation by insulin in liver.
Volume: 300
Issue: 5625
Pages: 1574-7
Publication  
First Author: Mouchiroud M
Year: 2019
Journal: JCI Insight
Title: The hepatokine Tsukushi is released in response to NAFLD and impacts cholesterol homeostasis.
Volume: 4
Issue: 15
Publication
First Author: Tartaglia LA
Year: 1997
Journal: J Biol Chem
Title: The leptin receptor.
Volume: 272
Issue: 10
Pages: 6093-6
Publication
First Author: Galloway CA
Year: 2010
Journal: Biochim Biophys Acta
Title: Metabolic regulation of APOBEC-1 complementation factor trafficking in mouse models of obesity and its positive correlation with the expression of ApoB protein in hepatocytes.
Volume: 1802
Issue: 11
Pages: 976-85
Publication
First Author: Herberg L
Year: 1977
Journal: Metabolism
Title: Laboratory animals exhibiting obesity and diabetes syndromes.
Volume: 26
Issue: 1
Pages: 59-99
Publication
First Author: Johnson PR
Year: 1972
Journal: J Lipid Res
Title: Cellularity of adipose depots in six strains of genetically obese mice.
Volume: 13
Issue: 1
Pages: 2-11
Publication
First Author: Bjørbaek C
Year: 1998
Journal: Mol Cell
Title: Identification of SOCS-3 as a potential mediator of central leptin resistance.
Volume: 1
Issue: 4
Pages: 619-25
Publication
First Author: Wueest S
Year: 2010
Journal: J Clin Invest
Title: Deletion of Fas in adipocytes relieves adipose tissue inflammation and hepatic manifestations of obesity in mice.
Volume: 120
Issue: 1
Pages: 191-202
Publication  
First Author: Hu T
Year: 2023
Journal: Metabolism
Title: PRDM16 exerts critical role in myocardial metabolism and energetics in type 2 diabetes induced cardiomyopathy.
Volume: 146
Pages: 155658
Publication
First Author: Shin MK
Year: 2019
Journal: Circ Res
Title: Leptin Induces Hypertension Acting on Transient Receptor Potential Melastatin 7 Channel in the Carotid Body.
Volume: 125
Issue: 11
Pages: 989-1002
Publication
First Author: Lee JH
Year: 2023
Journal: Am J Physiol Endocrinol Metab
Title: Endoplasmic reticulum stress in pancreatic β cells induces incretin desensitization and β-cell dysfunction via ATF4-mediated PDE4D expression.
Volume: 325
Issue: 5
Pages: E448-E465
Publication
First Author: Xu W
Year: 2020
Journal: J Diabetes Investig
Title: Wingless-type MMTV integration site family member 5a is a key inhibitor of islet stellate cells activation.
Volume: 11
Issue: 2
Pages: 307-314
Publication
First Author: Schwartz MW
Year: 1996
Journal: Diabetes
Title: Specificity of leptin action on elevated blood glucose levels and hypothalamic neuropeptide Y gene expression in ob/ob mice.
Volume: 45
Issue: 4
Pages: 531-5
Publication
First Author: Lindstrom SI
Year: 2019
Journal: J Diabetes Complications
Title: Diabetes induces IL-17A-Act1-FADD-dependent retinal endothelial cell death and capillary degeneration.
Volume: 33
Issue: 9
Pages: 668-674
Publication
First Author: Khan S
Year: 2014
Journal: J Clin Invest
Title: Lipotoxic disruption of NHE1 interaction with PI(4,5)P2 expedites proximal tubule apoptosis.
Volume: 124
Issue: 3
Pages: 1057-68
Publication
First Author: Huang S
Year: 2019
Journal: Viral Immunol
Title: Targeting Peroxisome Proliferator-Activated Receptor-Gamma Decreases Host Mortality After Influenza Infection in Obese Mice.
Volume: 32
Issue: 4
Pages: 161-169
Publication
First Author: Kämpfer H
Year: 2003
Journal: J Invest Dermatol
Title: Expression and activity of arginase isoenzymes during normal and diabetes-impaired skin repair.
Volume: 121
Issue: 6
Pages: 1544-51
Publication
First Author: Lee J
Year: 2017
Journal: PLoS One
Title: Interaction of IL-6 and TNF-α contributes to endothelial dysfunction in type 2 diabetic mouse hearts.
Volume: 12
Issue: 11
Pages: e0187189
Publication    
First Author: Marcel N
Year: 2016
Journal: Elife
Title: Notch1 regulated autophagy controls survival and suppressor activity of activated murine T-regulatory cells.
Volume: 5
Publication
First Author: Koh EH
Year: 2007
Journal: Diabetes
Title: Essential role of mitochondrial function in adiponectin synthesis in adipocytes.
Volume: 56
Issue: 12
Pages: 2973-81
Publication
First Author: Lu Y
Year: 2014
Journal: J Clin Invest
Title: Periostin promotes liver steatosis and hypertriglyceridemia through downregulation of PPARα.
Volume: 124
Issue: 8
Pages: 3501-13
Publication
First Author: Barile GR
Year: 2005
Journal: Invest Ophthalmol Vis Sci
Title: The RAGE axis in early diabetic retinopathy.
Volume: 46
Issue: 8
Pages: 2916-24
Publication
First Author: Huang Z
Year: 2017
Journal: Cell Rep
Title: Uncoupling the Mitogenic and Metabolic Functions of FGF1 by Tuning FGF1-FGF Receptor Dimer Stability.
Volume: 20
Issue: 7
Pages: 1717-1728
Publication
First Author: Satapati S
Year: 2017
Journal: J Lipid Res
Title: GPR120 suppresses adipose tissue lipolysis and synergizes with GPR40 in antidiabetic efficacy.
Volume: 58
Issue: 8
Pages: 1561-1578
Publication
First Author: Pradas-Juni M
Year: 2020
Journal: Nat Commun
Title: A MAFG-lncRNA axis links systemic nutrient abundance to hepatic glucose metabolism.
Volume: 11
Issue: 1
Pages: 644
Publication
First Author: Liang CF
Year: 2013
Journal: Arterioscler Thromb Vasc Biol
Title: Toll-like receptor 4 mutation protects obese mice against endothelial dysfunction by decreasing NADPH oxidase isoforms 1 and 4.
Volume: 33
Issue: 4
Pages: 777-84
Publication
First Author: Gloaguen I
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Ciliary neurotrophic factor corrects obesity and diabetes associated with leptin deficiency and resistance.
Volume: 94
Issue: 12
Pages: 6456-61
Publication
First Author: Han KL
Year: 2008
Journal: Diabetes
Title: Therapeutic potential of peroxisome proliferators--activated receptor-alpha/gamma dual agonist with alleviation of endoplasmic reticulum stress for the treatment of diabetes.
Volume: 57
Issue: 3
Pages: 737-45
Publication
First Author: Lu A
Year: 2011
Journal: Am J Pathol
Title: Blockade of TSP1-dependent TGF-β activity reduces renal injury and proteinuria in a murine model of diabetic nephropathy.
Volume: 178
Issue: 6
Pages: 2573-86
Publication
First Author: Shen L
Year: 2014
Journal: J Biol Chem
Title: Hepatic differentiated embryo-chondrocyte-expressed gene 1 (Dec1) inhibits sterol regulatory element-binding protein-1c (Srebp-1c) expression and alleviates fatty liver phenotype.
Volume: 289
Issue: 34
Pages: 23332-42
Publication
First Author: Chong AC
Year: 2015
Journal: Diabetes
Title: Distinct networks of leptin- and insulin-sensing neurons regulate thermogenic responses to nutritional and cold challenges.
Volume: 64
Issue: 1
Pages: 137-46
Publication
First Author: Ottaway N
Year: 2015
Journal: Cell Metab
Title: Diet-induced obese mice retain endogenous leptin action.
Volume: 21
Issue: 6
Pages: 877-82
Publication  
First Author: Blum B
Year: 2014
Journal: Elife
Title: Reversal of β cell de-differentiation by a small molecule inhibitor of the TGFβ pathway.
Volume: 3
Pages: e02809
Publication
First Author: Kolumam G
Year: 2017
Journal: PLoS One
Title: IL-22R Ligands IL-20, IL-22, and IL-24 Promote Wound Healing in Diabetic db/db Mice.
Volume: 12
Issue: 1
Pages: e0170639
Publication
First Author: Velmurugan GV
Year: 2012
Journal: Am J Physiol Heart Circ Physiol
Title: Calcium homeostasis in vascular smooth muscle cells is altered in type 2 diabetes by Bcl-2 protein modulation of InsP3R calcium release channels.
Volume: 302
Issue: 1
Pages: H124-34
Publication
First Author: Furusawa Y
Year: 2014
Journal: Genes Cells
Title: Nrf2 induces fibroblast growth factor 21 in diabetic mice.
Volume: 19
Issue: 12
Pages: 864-78
Publication
First Author: Meakin PJ
Year: 2018
Journal: Nat Commun
Title: The beta secretase BACE1 regulates the expression of insulin receptor in the liver.
Volume: 9
Issue: 1
Pages: 1306
Publication
First Author: Briere DA
Year: 2018
Journal: Diabetes
Title: Mechanisms to Elevate Endogenous GLP-1 Beyond Injectable GLP-1 Analogs and Metabolic Surgery.
Volume: 67
Issue: 2
Pages: 309-320
Publication
First Author: Wei K
Year: 2013
Journal: Nat Med
Title: A liver Hif-2α-Irs2 pathway sensitizes hepatic insulin signaling and is modulated by Vegf inhibition.
Volume: 19
Issue: 10
Pages: 1331-1337
Publication
First Author: Mathews JA
Year: 2018
Journal: Am J Respir Cell Mol Biol
Title: Augmented Responses to Ozone in Obese Mice Require IL-17A and Gastrin-Releasing Peptide.
Volume: 58
Issue: 3
Pages: 341-351
Publication
First Author: Chaudhari S
Year: 2022
Journal: Am J Physiol Cell Physiol
Title: Neogenin pathway positively regulates fibronectin production by glomerular mesangial cells.
Volume: 323
Issue: 1
Pages: C226-C235
Publication  
First Author: Yamagata R
Year: 2020
Journal: Biochem Pharmacol
Title: Downregulation of spinal angiotensin converting enzyme 2 is involved in neuropathic pain associated with type 2 diabetes mellitus in mice.
Volume: 174
Pages: 113825
Publication  
First Author: Callera GE
Year: 2016
Journal: Biosci Rep
Title: Differential renal effects of candesartan at high and ultra-high doses in diabetic mice-potential role of the ACE2/AT2R/Mas axis.
Volume: 36
Issue: 5
Publication
First Author: Kaiyala KJ
Year: 2010
Journal: Diabetes
Title: Identification of body fat mass as a major determinant of metabolic rate in mice.
Volume: 59
Issue: 7
Pages: 1657-66
Publication
First Author: Shibata S
Year: 2012
Journal: J Immunol
Title: Adiponectin regulates cutaneous wound healing by promoting keratinocyte proliferation and migration via the ERK signaling pathway.
Volume: 189
Issue: 6
Pages: 3231-41
Publication
First Author: Procaccini C
Year: 2012
Journal: J Immunol
Title: Leptin-induced mTOR activation defines a specific molecular and transcriptional signature controlling CD4+ effector T cell responses.
Volume: 189
Issue: 6
Pages: 2941-53
Publication
First Author: Zhang K
Year: 2012
Journal: Endocrinology
Title: Hepatic suppression of Foxo1 and Foxo3 causes hypoglycemia and hyperlipidemia in mice.
Volume: 153
Issue: 2
Pages: 631-46
Publication
First Author: Shahzad K
Year: 2015
Journal: Kidney Int
Title: Nlrp3-inflammasome activation in non-myeloid-derived cells aggravates diabetic nephropathy.
Volume: 87
Issue: 1
Pages: 74-84
Publication
First Author: Tsen F
Year: 2013
Journal: Mol Cell Biol
Title: Extracellular heat shock protein 90 signals through subdomain II and the NPVY motif of LRP-1 receptor to Akt1 and Akt2: a circuit essential for promoting skin cell migration in vitro and wound healing in vivo.
Volume: 33
Issue: 24
Pages: 4947-59
Publication
First Author: Ka SM
Year: 2012
Journal: Diabetologia
Title: Kidney-targeting Smad7 gene transfer inhibits renal TGF-β/MAD homologue (SMAD) and nuclear factor κB (NF-κB) signalling pathways, and improves diabetic nephropathy in mice.
Volume: 55
Issue: 2
Pages: 509-19
Publication
First Author: Pfuhlmann K
Year: 2018
Journal: Diabetes
Title: Celastrol-Induced Weight Loss Is Driven by Hypophagia and Independent From UCP1.
Volume: 67
Issue: 11
Pages: 2456-2465
Publication
First Author: Kassan M
Year: 2014
Journal: Am J Physiol Heart Circ Physiol
Title: Enhanced p22phox expression impairs vascular function through p38 and ERK1/2 MAP kinase-dependent mechanisms in type 2 diabetic mice.
Volume: 306
Issue: 7
Pages: H972-80
Publication
First Author: Akasaka Y
Year: 2010
Journal: Biochim Biophys Acta
Title: Direct evidence for leptin-induced lipid oxidation independent of long-form leptin receptor.
Volume: 1801
Issue: 10
Pages: 1115-22
Publication
First Author: Berk PD
Year: 1999
Journal: J Biol Chem
Title: Selective up-regulation of fatty acid uptake by adipocytes characterizes both genetic and diet-induced obesity in rodents.
Volume: 274
Issue: 40
Pages: 28626-31
Publication
First Author: Leiter EH
Year: 1987
Journal: J Immunol
Title: Effect of immunodeficiency on diabetogenesis in genetically diabetic (db/db) mice.
Volume: 138
Issue: 10
Pages: 3224-9
Publication
First Author: Zheng X
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Triggering of a Dll4-Notch1 loop impairs wound healing in diabetes.
Volume: 116
Issue: 14
Pages: 6985-6994