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Search results 2101 to 2200 out of 2663 for Psen1

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Category: Publication
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Type Details Score
Publication
35984475 | J:330857
 
First Author: Mishra R
Year: 2022
Journal: J Exp Med
Title: Augmenting neurogenesis rescues memory impairments in Alzheimer's disease by restoring the memory-storing neurons.
Volume: 219
Issue: 9
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Publication
31474828 | J:284351
 
First Author: Nam Y
Year: 2019
Journal: Front Mol Neurosci
Title: ALWPs Improve Cognitive Function and Regulate Aβ Plaque and Tau Hyperphosphorylation in a Mouse Model of Alzheimer's Disease.
Volume: 12
Pages: 192
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Publication
36939283 | J:350959
First Author: Kumro J
Year: 2023
Journal: Cereb Cortex
Title: Chronic basal forebrain activation improves spatial memory, boosts neurotrophin receptor expression, and lowers BACE1 and Aβ42 levels in the cerebral cortex in mice.
Volume: 33
Issue: 12
Pages: 7627-7641
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Publication
32660121 | J:327385
 
First Author: Han KM
Year: 2020
Journal: Cells
Title: Regorafenib Regulates AD Pathology, Neuroinflammation, and Dendritic Spinogenesis in Cells and a Mouse Model of AD.
Volume: 9
Issue: 7
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Publication
32958021 | J:327387
First Author: Shippy DC
Year: 2020
Journal: J Neuroinflammation
Title: β-Hydroxybutyrate inhibits inflammasome activation to attenuate Alzheimer's disease pathology.
Volume: 17
Issue: 1
Pages: 280
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Publication
39542183 | J:361433
First Author: Lee Y
Year: 2024
Journal: Biochem Pharmacol
Title: 3,4,5-trimethoxycinnamic acid methyl ester isolated from Polygala tenuifolia enhances hippocampal LTP through PKA and calcium-permeable AMPA receptor.
Volume: 230
Issue: Pt 3
Pages: 116622
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Publication
39026249 | J:359157
First Author: Wang Z
Year: 2024
Journal: J Neuroinflammation
Title: Herpes simplex virus 1 accelerates the progression of Alzheimer's disease by modulating microglial phagocytosis and activating NLRP3 pathway.
Volume: 21
Issue: 1
Pages: 176
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Publication
37774676 | J:341730
First Author: Lu Z
Year: 2023
Journal: Cell
Title: Tracking cell-type-specific temporal dynamics in human and mouse brains.
Volume: 186
Issue: 20
Pages: 4345-4364.e24
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Publication
36462718 | J:332229
 
First Author: Zhang H
Year: 2023
Journal: Neurobiol Dis
Title: Degenerate mapping of environmental location presages deficits in object-location encoding and memory in the 5xFAD mouse model for Alzheimer's disease.
Volume: 176
Pages: 105939
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Publication
38496847 | J:359158
First Author: Gao S
Year: 2024
Journal: Heliyon
Title: Dynamics of N6-methyladenosine modification during Alzheimer's disease development.
Volume: 10
Issue: 6
Pages: e26911
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Publication
37164302 | J:341772
 
First Author: Yao J
Year: 2023
Journal: Neuroscience
Title: A Gain-of-function Mutation in the Gating Domain of ITPR1 Impairs Motor Movement and Increases Thermal and Mechanical Sensitivity.
Volume: 522
Pages: 11-22
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Publication
32619873 | J:298312
 
First Author: Wang S
Year: 2020
Journal: Neurobiol Aging
Title: Early-stage dysfunction of hippocampal theta and gamma oscillations and its modulation of neural network in a transgenic 5xFAD mouse model.
Volume: 94
Pages: 121-129
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Publication
34856990 | J:327391
First Author: Rui W
Year: 2021
Journal: J Neuroinflammation
Title: Systemic inflammasome activation and pyroptosis associate with the progression of amnestic mild cognitive impairment and Alzheimer's disease.
Volume: 18
Issue: 1
Pages: 280
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Publication
28345579 | J:355618
 
First Author: Zhang Z
Year: 2017
Journal: Nat Commun
Title: Inhibition of delta-secretase improves cognitive functions in mouse models of Alzheimer's disease.
Volume: 8
Pages: 14740
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Publication
33422057 | J:327388
First Author: Fassler M
Year: 2021
Journal: J Neuroinflammation
Title: Engagement of TREM2 by a novel monoclonal antibody induces activation of microglia and improves cognitive function in Alzheimer's disease models.
Volume: 18
Issue: 1
Pages: 19
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Publication
35717259 | J:347605
First Author: Zhao P
Year: 2022
Journal: Mol Neurodegener
Title: LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions.
Volume: 17
Issue: 1
Pages: 44
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Publication
33758244 | J:304922
First Author: Rosales Jubal E
Year: 2021
Journal: Sci Rep
Title: Acitretin reverses early functional network degradation in a mouse model of familial Alzheimer's disease.
Volume: 11
Issue: 1
Pages: 6649
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Publication
39392753 | J:358119
First Author: Osborne OM
Year: 2024
Journal: Cell Rep
Title: Post-stroke hippocampal neurogenesis is impaired by microvascular dysfunction and PI3K signaling in cerebral amyloid angiopathy.
Volume: 43
Issue: 10
Pages: 114848
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Publication
32599514 | J:298313
 
First Author: Weible AP
Year: 2020
Journal: Neurobiol Aging
Title: 5XFAD mice show early-onset gap encoding deficits in the auditory cortex.
Volume: 94
Pages: 101-110
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Publication
31929163 | J:355624
First Author: Ano Y
Year: 2020
Journal: J Alzheimers Dis
Title: β-Lactolin, a Whey-Derived Lacto-Tetrapeptide, Prevents Alzheimer's Disease Pathologies and Cognitive Decline.
Volume: 73
Issue: 4
Pages: 1331-1342
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Publication
22503002 | J:191369
First Author: Kim C
Year: 2013
Journal: Neurobiol Aging
Title: O-linked β-N-acetylglucosaminidase inhibitor attenuates β-amyloid plaque and rescues memory impairment.
Volume: 34
Issue: 1
Pages: 275-85
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Publication
32791516 | J:294346
First Author: Jeong J
Year: 2020
Journal: PLoS One
Title: JBPOS0101 regulates amyloid beta, tau, and glial cells in an Alzheimer's disease model.
Volume: 15
Issue: 8
Pages: e0237153
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Publication
36653878 | J:334413
First Author: Vasciaveo V
Year: 2023
Journal: Acta Neuropathol Commun
Title: Sleep fragmentation affects glymphatic system through the different expression of AQP4 in wild type and 5xFAD mouse models.
Volume: 11
Issue: 1
Pages: 16
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Publication
36494892 | J:334412
First Author: Liang X
Year: 2023
Journal: Aging Cell
Title: Exosomal miR-532-5p induced by long-term exercise rescues blood-brain barrier function in 5XFAD mice via downregulation of EPHA4.
Volume: 22
Issue: 1
Pages: e13748
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Publication
25008761 | J:215635
 
First Author: Fragkouli A
Year: 2014
Journal: Neurobiol Dis
Title: Neuroprotective role of MMP-9 overexpression in the brain of Alzheimer's 5xFAD mice.
Volume: 70
Pages: 179-89
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Publication
35046767 | J:349770
 
First Author: Viola KL
Year: 2021
Journal: Front Neurosci
Title: The Therapeutic and Diagnostic Potential of Amyloid β Oligomers Selective Antibodies to Treat Alzheimer's Disease.
Volume: 15
Pages: 768646
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Publication
35496999 | J:324605
First Author: Dong Q
Year: 2022
Journal: iScience
Title: Familial natural short sleep mutations reduce Alzheimer pathology in mice.
Volume: 25
Issue: 4
Pages: 103964
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Publication
36254682 | J:330956
 
First Author: Monzón-Sandoval J
Year: 2022
Journal: Dis Model Mech
Title: Lipopolysaccharide distinctively alters human microglia transcriptomes to resemble microglia from Alzheimer's disease mouse models.
Volume: 15
Issue: 10
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Publication
36219197 | J:350035
 
First Author: Jain N
Year: 2023
Journal: J Exp Med
Title: Chronic TREM2 activation exacerbates Aβ-associated tau seeding and spreading.
Volume: 220
Issue: 1
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34745215 | J:319460
 
First Author: Lim KH
Year: 2021
Journal: Front Genet
Title: Identifying New COVID-19 Receptor Neuropilin-1 in Severe Alzheimer's Disease Patients Group Brain Using Genome-Wide Association Study Approach.
Volume: 12
Pages: 741175
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Publication
31618637 | J:284703
First Author: Carrillo-Jimenez A
Year: 2019
Journal: Cell Rep
Title: TET2 Regulates the Neuroinflammatory Response in Microglia.
Volume: 29
Issue: 3
Pages: 697-713.e8
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Publication
37407605 | J:337946
First Author: Lee D
Year: 2023
Journal: Sci Rep
Title: Carprofen alleviates Alzheimer-like phenotypes of 5XFAD transgenic mice by targeting the pathological hallmarks induced by amyloid-β aggregation.
Volume: 13
Issue: 1
Pages: 10889
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Publication
33009465 | J:299084
First Author: Farid MM
Year: 2020
Journal: Sci Rep
Title: Trigonelline recovers memory function in Alzheimer's disease model mice: evidence of brain penetration and target molecule.
Volume: 10
Issue: 1
Pages: 16424
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Publication
30224067 | J:272467
First Author: Kim DH
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Effect of growth differentiation factor-15 secreted by human umbilical cord blood-derived mesenchymal stem cells on amyloid beta levels in in vitro and in vivo models of Alzheimer's disease.
Volume: 504
Issue: 4
Pages: 933-940
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Publication
34312845 | J:319467
First Author: Choi C
Year: 2021
Journal: J Pathol
Title: DSCR1 upregulation enhances dural meningeal lymphatic drainage to attenuate amyloid pathology of Alzheimer's disease.
Volume: 255
Issue: 3
Pages: 296-310
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Publication
33139698 | J:297772
First Author: Trzeciakiewicz H
Year: 2020
Journal: Nat Commun
Title: An HDAC6-dependent surveillance mechanism suppresses tau-mediated neurodegeneration and cognitive decline.
Volume: 11
Issue: 1
Pages: 5522
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Publication
27265785 | J:249653
First Author: Neuner SM
Year: 2017
Journal: Behav Brain Res
Title: Hippocampal proteomics defines pathways associated with memory decline and resilience in normal aging and Alzheimer's disease mouse models.
Volume: 322
Issue: Pt B
Pages: 288-298
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Publication
39316084 | J:359168
 
First Author: Cao Q
Year: 2024
Journal: J Exp Med
Title: Transport of β-amyloid from brain to eye causes retinal degeneration in Alzheimer's disease.
Volume: 221
Issue: 11
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Publication
33397809 | J:300753
 
First Author: Kim SH
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Prediction of Alzheimer's disease-specific phospholipase c gamma-1 SNV by deep learning-based approach for high-throughput screening.
Volume: 118
Issue: 3
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Publication
37620442 | J:350080
First Author: Jorfi M
Year: 2023
Journal: Nat Neurosci
Title: Infiltrating CD8(+) T cells exacerbate Alzheimer's disease pathology in a 3D human neuroimmune axis model.
Volume: 26
Issue: 9
Pages: 1489-1504
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Publication
39490772 | J:360709
 
First Author: He K
Year: 2024
Journal: Free Radic Biol Med
Title: Sevoflurane exposure accelerates the onset of cognitive impairment via promoting p-Drp1(S616)-mediated mitochondrial fission in a mouse model of Alzheimer's disease.
Volume: 225
Pages: 699-710
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Publication
34776451 | J:359233
First Author: Chum PP
Year: 2022
Journal: J Alzheimers Dis
Title: Cerebrovascular microRNA Expression Profile During Early Development of Alzheimer's Disease in a Mouse Model.
Volume: 85
Issue: 1
Pages: 91-113
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Publication
38884283 | J:360714
First Author: Yao Y
Year: 2024
Journal: Alzheimers Dement
Title: A small-molecule microtubule-stabilizing agent safely reduces Aβ plaque and tau pathology in transgenic mouse models of Alzheimer's disease.
Volume: 20
Issue: 7
Pages: 4540-4558
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Publication
39394148 | J:359171
First Author: Xiong X
Year: 2024
Journal: Cell Death Dis
Title: NAD(+)-boosting agent nicotinamide mononucleotide potently improves mitochondria stress response in Alzheimer's disease via ATF4-dependent mitochondrial UPR.
Volume: 15
Issue: 10
Pages: 744
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Publication
37847596 | J:359232
First Author: Kandi S
Year: 2023
Journal: J Proteome Res
Title: Amyloid β Proteoforms Elucidated by Quantitative LC/MS in the 5xFAD Mouse Model of Alzheimer's Disease.
Volume: 22
Issue: 11
Pages: 3475-3488
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Publication
39434878 | J:359173
 
First Author: Lee HJ
Year: 2024
Journal: Front Immunol
Title: Erlotinib regulates short-term memory, tau/Aβ pathology, and astrogliosis in mouse models of AD.
Volume: 15
Pages: 1421455
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Publication
34170616 | J:359229
First Author: Su SH
Year: 2021
Journal: Small
Title: Ultrasensitive Multiparameter Phenotyping of Rare Cells Using an Integrated Digital-Molecular-Counting Microfluidic Well Plate.
Volume: 17
Issue: 31
Pages: e2101743
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Publication
39431020 | J:359174
First Author: Shojaei M
Year: 2024
Journal: Theranostics
Title: PET imaging of microglia in Alzheimer's disease using copper-64 labeled TREM2 antibodies.
Volume: 14
Issue: 16
Pages: 6319-6336
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Publication
31932797 | J:284722
First Author: Zhou Y
Year: 2020
Journal: Nat Med
Title: Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer's disease.
Volume: 26
Issue: 1
Pages: 131-142
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Publication
39205389 | J:360712
First Author: Fonseca-Gomes J
Year: 2024
Journal: Mol Ther
Title: A small TAT-TrkB peptide prevents BDNF receptor cleavage and restores synaptic physiology in Alzheimer's disease.
Volume: 32
Issue: 10
Pages: 3372-3401
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Publication
25637807 | J:221806
 
First Author: Sethi M
Year: 2015
Journal: Neuroscience
Title: Increased fragmentation of sleep-wake cycles in the 5XFAD mouse model of Alzheimer's disease.
Volume: 290
Pages: 80-9
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Publication
23402900 | J:211692
First Author: Rojas S
Year: 2013
Journal: Neurobiol Aging
Title: In vivo evaluation of amyloid deposition and brain glucose metabolism of 5XFAD mice using positron emission tomography.
Volume: 34
Issue: 7
Pages: 1790-8
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Publication
39268577 | J:355470
First Author: Campoy-Campos G
Year: 2024
Journal: Nucleic Acids Res
Title: RTP801 interacts with the tRNA ligase complex and dysregulates its RNA ligase activity in Alzheimer's disease.
Volume: 52
Issue: 18
Pages: 11158-11176
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Publication
37984409 | J:358193
First Author: Na D
Year: 2023
Journal: Mol Syst Biol
Title: A multi-layered network model identifies Akt1 as a common modulator of neurodegeneration.
Volume: 19
Issue: 12
Pages: e11801
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Publication
33737550 | J:305021
First Author: Lim JKH
Year: 2021
Journal: Sci Rep
Title: Retinal hyperspectral imaging in the 5xFAD mouse model of Alzheimer's disease.
Volume: 11
Issue: 1
Pages: 6387
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Publication
37333676 | J:351093
 
First Author: Smith S
Year: 2023
Journal: Aging Brain
Title: The 5XFAD mouse model of Alzheimer's disease displays age-dependent deficits in habituation to a novel environment.
Volume: 3
Pages: 100078
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Publication
39522980 | J:360722
First Author: Matsuoka Y
Year: 2024
Journal: Biol Pharm Bull
Title: Expression Profiles of Brain-Derived Neurotrophic Factor Splice Variants in the Hippocampus of Alzheimer's Disease Model Mouse.
Volume: 47
Issue: 11
Pages: 1858-1867
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Publication
31741224 | J:319510
First Author: Kim N
Year: 2020
Journal: Neurotherapeutics
Title: Picrorhiza kurroa Prevents Memory Deficits by Inhibiting NLRP3 Inflammasome Activation and BACE1 Expression in 5xFAD Mice.
Volume: 17
Issue: 1
Pages: 189-199
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Publication
39557828 | J:360720
First Author: Wang X
Year: 2024
Journal: Cell Discov
Title: Sodium oligomannate disrupts the adherence of Rib(high) bacteria to gut epithelia to block SAA-triggered Th1 inflammation in 5XFAD transgenic mice.
Volume: 10
Issue: 1
Pages: 115
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Publication
29321225 | J:259750
First Author: Song WM
Year: 2018
Journal: J Exp Med
Title: Humanized TREM2 mice reveal microglia-intrinsic and -extrinsic effects of R47H polymorphism.
Volume: 215
Issue: 3
Pages: 745-760
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Publication
39044270 | J:360704
First Author: Chen M
Year: 2024
Journal: Transl Neurodegener
Title: Dorsal raphe nucleus-hippocampus serotonergic circuit underlies the depressive and cognitive impairments in 5×FAD male mice.
Volume: 13
Issue: 1
Pages: 34
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Publication
38032015 | J:350118
First Author: Chumin EJ
Year: 2024
Journal: Alzheimers Dement
Title: Brain metabolic network covariance and aging in a mouse model of Alzheimer's disease.
Volume: 20
Issue: 3
Pages: 1538-1549
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Publication
38965625 | J:360733
First Author: Lee S
Year: 2024
Journal: Chin Med
Title: Rhei Undulati Rhizoma attenuates memory decline and reduces amyloid-β induced neuritic dystrophy in 5xFAD mouse.
Volume: 19
Issue: 1
Pages: 95
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Publication
37961834 | J:350115
First Author: Odfalk KF
Year: 2024
Journal: Hippocampus
Title: Hippocampal TMEM55B overexpression in the 5XFAD mouse model of Alzheimer's disease.
Volume: 34
Issue: 1
Pages: 29-35
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Publication
19675248 | J:151932
First Author: Auffret A
Year: 2009
Journal: J Neurosci
Title: Age-dependent impairment of spine morphology and synaptic plasticity in hippocampal CA1 neurons of a presenilin 1 transgenic mouse model of Alzheimer's disease.
Volume: 29
Issue: 32
Pages: 10144-52
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Publication
23674689 | J:197420
First Author: Veeraraghavalu K
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Mutant presenilin 1 expression in excitatory neurons impairs enrichment-mediated phenotypes of adult hippocampal progenitor cells.
Volume: 110
Issue: 22
Pages: 9148-53
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Publication
19917299 | J:179562
First Author: Hou Y
Year: 2010
Journal: Neuropharmacology
Title: Anti-depressant natural flavonols modulate BDNF and beta amyloid in neurons and hippocampus of double TgAD mice.
Volume: 58
Issue: 6
Pages: 911-20
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Publication
29937276 | J:269650
First Author: Readhead B
Year: 2018
Journal: Neuron
Title: Multiscale Analysis of Independent Alzheimer's Cohorts Finds Disruption of Molecular, Genetic, and Clinical Networks by Human Herpesvirus.
Volume: 99
Issue: 1
Pages: 64-82.e7
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Publication
27354375 | J:236794
First Author: Ezratty EJ
Year: 2016
Journal: J Cell Biol
Title: A Presenilin-2-ARF4 trafficking axis modulates Notch signaling during epidermal differentiation.
Volume: 214
Issue: 1
Pages: 89-101
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Publication
31601621 | J:282225
First Author: Tiscione SA
Year: 2019
Journal: J Cell Biol
Title: Disease-associated mutations in Niemann-Pick type C1 alter ER calcium signaling and neuronal plasticity.
Volume: 218
Issue: 12
Pages: 4141-4156
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Publication
25231903 | J:217304
First Author: Tagawa K
Year: 2015
Journal: Hum Mol Genet
Title: Comprehensive phosphoproteome analysis unravels the core signaling network that initiates the earliest synapse pathology in preclinical Alzheimer's disease brain.
Volume: 24
Issue: 2
Pages: 540-58
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11337275 | J:78664
First Author: Jankowsky JL
Year: 2001
Journal: Biomol Eng
Title: Co-expression of multiple transgenes in mouse CNS: a comparison of strategies.
Volume: 17
Issue: 6
Pages: 157-65
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25747037 | J:221130
 
First Author: Collins JM
Year: 2015
Journal: Exp Neurol
Title: The effect of focal brain injury on beta-amyloid plaque deposition, inflammation and synapses in the APP/PS1 mouse model of Alzheimer's disease.
Volume: 267
Pages: 219-29
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Publication
24655396 | J:223699
First Author: Flanigan TJ
Year: 2014
Journal: Genes Brain Behav
Title: Abnormal vibrissa-related behavior and loss of barrel field inhibitory neurons in 5xFAD transgenics.
Volume: 13
Issue: 5
Pages: 488-500
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Publication
35915180 | J:335653
First Author: Liu CC
Year: 2022
Journal: Nat Neurosci
Title: Peripheral apoE4 enhances Alzheimer's pathology and impairs cognition by compromising cerebrovascular function.
Volume: 25
Issue: 8
Pages: 1020-1033
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Publication
38587131 | J:350558
First Author: Späte E
Year: 2024
Journal: Glia
Title: Downregulated expression of lactate dehydrogenase in adult oligodendrocytes and its implication for the transfer of glycolysis products to axons.
Volume: 72
Issue: 8
Pages: 1374-1391
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Publication
34034683 | J:311235
First Author: Ringland C
Year: 2021
Journal: BMC Neurosci
Title: MMP9 modulation improves specific neurobehavioral deficits in a mouse model of Alzheimer's disease.
Volume: 22
Issue: 1
Pages: 39
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Publication
35443157 | J:324839
First Author: Roy ER
Year: 2022
Journal: Immunity
Title: Concerted type I interferon signaling in microglia and neural cells promotes memory impairment associated with amyloid β plaques.
Volume: 55
Issue: 5
Pages: 879-894.e6
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Publication
34272583 | J:350898
First Author: Roos TT
Year: 2021
Journal: Acta Neuropathol
Title: Neuronal spreading and plaque induction of intracellular Aβ and its disruption of Aβ homeostasis.
Volume: 142
Issue: 4
Pages: 669-687
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Publication
34417591 | J:335307
First Author: Islam MR
Year: 2021
Journal: Nat Metab
Title: Exercise hormone irisin is a critical regulator of cognitive function.
Volume: 3
Issue: 8
Pages: 1058-1070
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Publication
32973044 | J:296602
First Author: Chen W
Year: 2020
Journal: J Neurosci
Title: 14,15-Epoxyeicosatrienoic Acid Alleviates Pathology in a Mouse Model of Alzheimer's Disease.
Volume: 40
Issue: 42
Pages: 8188-8203
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Publication
28806762 | J:244104
First Author: Rocchi A
Year: 2017
Journal: PLoS Genet
Title: A Becn1 mutation mediates hyperactive autophagic sequestration of amyloid oligomers and improved cognition in Alzheimer's disease.
Volume: 13
Issue: 8
Pages: e1006962
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Publication
38490196 | J:347655
First Author: Escoubas CC
Year: 2024
Journal: Cell
Title: Type-I-interferon-responsive microglia shape cortical development and behavior.
Volume: 187
Issue: 8
Pages: 1936-1954.e24
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Publication
32424276 | J:293187
First Author: Pao PC
Year: 2020
Journal: Nat Commun
Title: HDAC1 modulates OGG1-initiated oxidative DNA damage repair in the aging brain and Alzheimer's disease.
Volume: 11
Issue: 1
Pages: 2484
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