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Search results 2201 to 2300 out of 2570 for Kras

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Category: Publication
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Type Details Score
Publication
24866151 | J:217845
First Author: González-Billalabeitia E
Year: 2014
Journal: Cancer Discov
Title: Vulnerabilities of PTEN-TP53-deficient prostate cancers to compound PARP-PI3K inhibition.
Volume: 4
Issue: 8
Pages: 896-904
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Publication
23845440 | J:199223
First Author: Karantanos T
Year: 2013
Journal: Cancer Cell
Title: GEMMs shine a light on resistance to androgen deprivation therapy for prostate cancer.
Volume: 24
Issue: 1
Pages: 11-3
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Publication
35954439 | J:335211
 
First Author: Baures M
Year: 2022
Journal: Cancers (Basel)
Title: Transcriptomic Signature and Growth Factor Regulation of Castration-Tolerant Prostate Luminal Progenitor Cells.
Volume: 14
Issue: 15
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Publication
16079851 | J:100683
First Author: Chen Z
Year: 2005
Journal: Nature
Title: Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis.
Volume: 436
Issue: 7051
Pages: 725-30
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Publication
23027128 | J:203243
First Author: Zheng Y
Year: 2013
Journal: Oncogene
Title: Protein tyrosine kinase 6 protects cells from anoikis by directly phosphorylating focal adhesion kinase and activating AKT.
Volume: 32
Issue: 36
Pages: 4304-12
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Publication
29202479 | J:258828
First Author: Shoag J
Year: 2018
Journal: J Clin Invest
Title: SPOP mutation drives prostate neoplasia without stabilizing oncogenic transcription factor ERG.
Volume: 128
Issue: 1
Pages: 381-386
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Publication
27728805 | J:236713
First Author: Dardenne E
Year: 2016
Journal: Cancer Cell
Title: N-Myc Induces an EZH2-Mediated Transcriptional Program Driving Neuroendocrine Prostate Cancer.
Volume: 30
Issue: 4
Pages: 563-577
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Publication
31277777 | J:309459
First Author: Shinde D
Year: 2019
Journal: Eur Urol Oncol
Title: Transcriptional Reprogramming and Inhibition of Tumor-propagating Stem-like Cells by EC-8042 in ERG-positive Prostate Cancer.
Volume: 2
Issue: 4
Pages: 415-424
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Publication
20679199 | J:163589
First Author: Furic L
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: eIF4E phosphorylation promotes tumorigenesis and is associated with prostate cancer progression.
Volume: 107
Issue: 32
Pages: 14134-9
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Publication
30333152 | J:271158
First Author: Elfandy H
Year: 2019
Journal: Mol Cancer Res
Title: Genetic and Epigenetic Determinants of Aggressiveness in Cribriform Carcinoma of the Prostate.
Volume: 17
Issue: 2
Pages: 446-456
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Publication
23856248 | J:201832
First Author: Zheng Y
Year: 2013
Journal: Cancer Res
Title: PTK6 activation at the membrane regulates epithelial-mesenchymal transition in prostate cancer.
Volume: 73
Issue: 17
Pages: 5426-37
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Publication
29335436 | J:257713
First Author: Chen M
Year: 2018
Journal: Nat Commun
Title: Deregulated PP1α phosphatase activity towards MAPK activation is antagonized by a tumor suppressive failsafe mechanism.
Volume: 9
Issue: 1
Pages: 159
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Publication
19176516 | J:261276
First Author: Nardella C
Year: 2009
Journal: Sci Signal
Title: Differential requirement of mTOR in postmitotic tissues and tumorigenesis.
Volume: 2
Issue: 55
Pages: ra2
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Publication
28274958 | J:243131
First Author: Patnaik A
Year: 2017
Journal: Cancer Discov
Title: Cabozantinib Eradicates Advanced Murine Prostate Cancer by Activating Antitumor Innate Immunity.
Volume: 7
Issue: 7
Pages: 750-765
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Publication
29335545 | J:260988
First Author: Chen M
Year: 2018
Journal: Nat Genet
Title: An aberrant SREBP-dependent lipogenic program promotes metastatic prostate cancer.
Volume: 50
Issue: 2
Pages: 206-218
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Publication
28807943 | J:245648
First Author: Bainor AJ
Year: 2017
Journal: Cancer Res
Title: Chromatin-Associated Protein SIN3B Prevents Prostate Cancer Progression by Inducing Senescence.
Volume: 77
Issue: 19
Pages: 5339-5348
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Publication
33186519 | J:300350
First Author: Guccini I
Year: 2021
Journal: Cancer Cell
Title: Senescence Reprogramming by TIMP1 Deficiency Promotes Prostate Cancer Metastasis.
Volume: 39
Issue: 1
Pages: 68-82.e9
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Publication
28603917 | J:245657
First Author: Sackmann Sala L
Year: 2017
Journal: J Pathol
Title: A rare castration-resistant progenitor cell population is highly enriched in Pten-null prostate tumours.
Volume: 243
Issue: 1
Pages: 51-64
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Publication
36928314 | J:352792
 
First Author: Wang ME
Year: 2023
Journal: J Clin Invest
Title: RB1-deficient prostate tumor growth and metastasis are vulnerable to ferroptosis induction via the E2F/ACSL4 axis.
Volume: 133
Issue: 10
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Publication
29309058 | J:275855
First Author: Bezzi M
Year: 2018
Journal: Nat Med
Title: Diverse genetic-driven immune landscapes dictate tumor progression through distinct mechanisms.
Volume: 24
Issue: 2
Pages: 165-175
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Publication
36868226 | J:347460
First Author: Bancaro N
Year: 2023
Journal: Cancer Cell
Title: Apolipoprotein E induces pathogenic senescent-like myeloid cells in prostate cancer.
Volume: 41
Issue: 3
Pages: 602-619.e11
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Publication
33500545 | J:306413
First Author: Albino D
Year: 2021
Journal: Commun Biol
Title: Circulating extracellular vesicles release oncogenic miR-424 in experimental models and patients with aggressive prostate cancer.
Volume: 4
Issue: 1
Pages: 119
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Publication
35216332 | J:321513
 
First Author: Sato H
Year: 2022
Journal: Int J Mol Sci
Title: Specific Gut Microbial Environment in Lard Diet-Induced Prostate Cancer Development and Progression.
Volume: 23
Issue: 4
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Publication
37386128 | J:338792
First Author: Vlajic K
Year: 2023
Journal: Oncogene
Title: Appearance of tuft cells during prostate cancer progression.
Volume: 42
Issue: 31
Pages: 2374-2385
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Publication
26206718 | J:224835
First Author: Belair CD
Year: 2015
Journal: EMBO Rep
Title: DGCR8 is essential for tumor progression following PTEN loss in the prostate.
Volume: 16
Issue: 9
Pages: 1219-32
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Publication
29142193 | J:338791
First Author: Wozniak DJ
Year: 2017
Journal: Nat Commun
Title: PTEN is a protein phosphatase that targets active PTK6 and inhibits PTK6 oncogenic signaling in prostate cancer.
Volume: 8
Issue: 1
Pages: 1508
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Publication
32219437 | J:289861
 
First Author: Hermanova I
Year: 2020
Journal: J Exp Med
Title: Genetic manipulation of LKB1 elicits lethal metastatic prostate cancer.
Volume: 217
Issue: 6
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Publication
34230470 | J:307918
First Author: Zoma M
Year: 2021
Journal: Nat Commun
Title: EZH2-induced lysine K362 methylation enhances TMPRSS2-ERG oncogenic activity in prostate cancer.
Volume: 12
Issue: 1
Pages: 4147
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Publication
35584006 | J:326292
First Author: Davidson SM
Year: 2022
Journal: Cancer Res
Title: Pyruvate Kinase M1 Suppresses Development and Progression of Prostate Adenocarcinoma.
Volume: 82
Issue: 13
Pages: 2403-2416
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Publication
25099011 | J:216207
First Author: Xie Y
Year: 2014
Journal: Mol Endocrinol
Title: Crosstalk between nuclear MET and SOX9/β-catenin correlates with castration-resistant prostate cancer.
Volume: 28
Issue: 10
Pages: 1629-39
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Publication
29056325 | J:251968
First Author: Malek M
Year: 2017
Journal: Mol Cell
Title: PTEN Regulates PI(3,4)P2 Signaling Downstream of Class I PI3K.
Volume: 68
Issue: 3
Pages: 566-580.e10
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Publication
32701507 | J:302324
First Author: Li F
Year: 2020
Journal: J Clin Invest
Title: ERG orchestrates chromatin interactions to drive prostate cell fate reprogramming.
Volume: 130
Issue: 11
Pages: 5924-5941
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Publication
23563312 | J:201460
First Author: Hanna SC
Year: 2013
Journal: J Clin Invest
Title: HIF1α and HIF2α independently activate SRC to promote melanoma metastases.
Volume: 123
Issue: 5
Pages: 2078-93
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Publication
18840652 | J:141132
First Author: Vaahtomeri K
Year: 2008
Journal: J Cell Sci
Title: Lkb1 is required for TGFbeta-mediated myofibroblast differentiation.
Volume: 121
Issue: Pt 21
Pages: 3531-40
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Publication
32807988 | J:305876
First Author: Guo W
Year: 2020
Journal: Nat Genet
Title: Single-cell transcriptomics identifies a distinct luminal progenitor cell type in distal prostate invagination tips.
Volume: 52
Issue: 9
Pages: 908-918
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Publication
28273450 | J:251063
First Author: Chen CF
Year: 2017
Journal: Cell Rep
Title: ATR Mutations Promote the Growth of Melanoma Tumors by Modulating the Immune Microenvironment.
Volume: 18
Issue: 10
Pages: 2331-2342
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Publication
24691994 | J:210809
First Author: Le Mercier I
Year: 2014
Journal: Cancer Res
Title: VISTA Regulates the Development of Protective Antitumor Immunity.
Volume: 74
Issue: 7
Pages: 1933-44
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Publication
24145418 | J:202916
First Author: Yuan P
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Phenformin enhances the therapeutic benefit of BRAF(V600E) inhibition in melanoma.
Volume: 110
Issue: 45
Pages: 18226-31
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Publication
24200692 | J:207627
First Author: Marsh Durban V
Year: 2013
Journal: J Clin Invest
Title: Differential AKT dependency displayed by mouse models of BRAFV600E-initiated melanoma.
Volume: 123
Issue: 12
Pages: 5104-18
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Publication
23796563 | J:200610
First Author: Antico Arciuch VG
Year: 2013
Journal: Cancer Res
Title: Inhibition of AMPK and Krebs cycle gene expression drives metabolic remodeling of Pten-deficient preneoplastic thyroid cells.
Volume: 73
Issue: 17
Pages: 5459-72
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Publication
36368445 | J:332391
     
First Author: Dong B
Year: 2022
Journal: J Invest Dermatol
Title: FZD6 Promotes Melanoma Cell Invasion but Not Proliferation by Regulating Canonical Wnt Signaling and Epithelial‒Mesenchymal Transition.
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Publication
22302806 | J:181347
First Author: Xiong Q
Year: 2012
Journal: J Neurosci
Title: PTEN regulation of local and long-range connections in mouse auditory cortex.
Volume: 32
Issue: 5
Pages: 1643-52
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Publication
27052162 | J:235087
First Author: Katlinskaya YV
Year: 2016
Journal: Cell Rep
Title: Suppression of Type I Interferon Signaling Overcomes Oncogene-Induced Senescence and Mediates Melanoma Development and Progression.
Volume: 15
Issue: 1
Pages: 171-80
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Publication
28174173 | J:240401
First Author: Wan L
Year: 2017
Journal: Cancer Discov
Title: The APC/C E3 Ligase Complex Activator FZR1 Restricts BRAF Oncogenic Function.
Volume: 7
Issue: 4
Pages: 424-441
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Publication
37270599 | J:354056
First Author: Yang J
Year: 2023
Journal: Mol Cancer
Title: CXCR2 expression during melanoma tumorigenesis controls transcriptional programs that facilitate tumor growth.
Volume: 22
Issue: 1
Pages: 92
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Publication
28368402 | J:247888
First Author: Cesarini V
Year: 2017
Journal: Oncogene
Title: Sox2 is not required for melanomagenesis, melanoma growth and melanoma metastasis in vivo.
Volume: 36
Issue: 31
Pages: 4508-4515
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Publication
21278735 | J:169306
First Author: Biton M
Year: 2011
Journal: Nat Immunol
Title: Epithelial microRNAs regulate gut mucosal immunity via epithelium-T cell crosstalk.
Volume: 12
Issue: 3
Pages: 239-46
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Publication
26818109 | J:231632
First Author: Jolly LA
Year: 2016
Journal: Cancer Res
Title: Fibroblast-Mediated Collagen Remodeling Within the Tumor Microenvironment Facilitates Progression of Thyroid Cancers Driven by BrafV600E and Pten Loss.
Volume: 76
Issue: 7
Pages: 1804-13
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Publication
24291004 | J:206975
First Author: Piovan E
Year: 2013
Journal: Cancer Cell
Title: Direct reversal of glucocorticoid resistance by AKT inhibition in acute lymphoblastic leukemia.
Volume: 24
Issue: 6
Pages: 766-76
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Publication
21575859 | J:172424
First Author: Carver BS
Year: 2011
Journal: Cancer Cell
Title: Reciprocal feedback regulation of PI3K and androgen receptor signaling in PTEN-deficient prostate cancer.
Volume: 19
Issue: 5
Pages: 575-86
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Publication
31331961 | J:278688
 
First Author: Jezek J
Year: 2019
Journal: J Cell Sci
Title: Synergistic repression of thyroid hyperplasia by cyclin C and Pten.
Volume: 132
Issue: 16
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Publication
30914431 | J:276351
First Author: Shurin GV
Year: 2019
Journal: Cancer Res
Title: Melanoma-Induced Reprogramming of Schwann Cell Signaling Aids Tumor Growth.
Volume: 79
Issue: 10
Pages: 2736-2747
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Publication
25472943 | J:221978
First Author: Deuker MM
Year: 2015
Journal: Cancer Discov
Title: PI3'-kinase inhibition forestalls the onset of MEK1/2 inhibitor resistance in BRAF-mutated melanoma.
Volume: 5
Issue: 2
Pages: 143-53
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Publication
32782145 | J:304228
First Author: Li XX
Year: 2020
Journal: Biochem Biophys Res Commun
Title: Schwann cell-specific Pten inactivation reveals essential role of the sympathetic nervous system activity in adipose tissue development.
Volume: 531
Issue: 2
Pages: 118-124
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Publication
28433543 | J:243339
First Author: Kim SH
Year: 2017
Journal: J Invest Dermatol
Title: Phenformin Inhibits Myeloid-Derived Suppressor Cells and Enhances the Anti-Tumor Activity of PD-1 Blockade in Melanoma.
Volume: 137
Issue: 8
Pages: 1740-1748
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Publication
33690225 | J:306045
 
First Author: Huang F
Year: 2021
Journal: J Clin Invest
Title: Inhibiting the MNK1/2-eIF4E axis impairs melanoma phenotype switching and potentiates antitumor immune responses.
Volume: 131
Issue: 8
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Publication
26390244 | J:228904
First Author: Herranz D
Year: 2015
Journal: Nat Med
Title: Metabolic reprogramming induces resistance to anti-NOTCH1 therapies in T cell acute lymphoblastic leukemia.
Volume: 21
Issue: 10
Pages: 1182-9
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Publication
23319880 | J:195067
 
First Author: Keng VW
Year: 2012
Journal: Sarcoma
Title: Conditional Inactivation of Pten with EGFR Overexpression in Schwann Cells Models Sporadic MPNST.
Volume: 2012
Pages: 620834
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Publication
30662519 | J:307277
First Author: Lui JW
Year: 2019
Journal: J Cancer
Title: The Efficiency of Verteporfin as a Therapeutic Option in Pre-Clinical Models of Melanoma.
Volume: 10
Issue: 1
Pages: 1-10
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Publication
31375534 | J:289994
First Author: Etzerodt A
Year: 2019
Journal: J Exp Med
Title: Specific targeting of CD163+ TAMs mobilizes inflammatory monocytes and promotes T cell-mediated tumor regression.
Volume: 216
Issue: 10
Pages: 2394-2411
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Publication
24746818 | J:277956
First Author: Luo X
Year: 2014
Journal: Cell Rep
Title: Isolation and molecular characterization of circulating melanoma cells.
Volume: 7
Issue: 3
Pages: 645-53
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Publication
33953176 | J:306090
First Author: Di Leo L
Year: 2021
Journal: Nat Commun
Title: Loss of Ambra1 promotes melanoma growth and invasion.
Volume: 12
Issue: 1
Pages: 2550
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Publication
36332622 | J:332355
First Author: Han M
Year: 2022
Journal: Cancer Cell
Title: FOXA2 drives lineage plasticity and KIT pathway activation in neuroendocrine prostate cancer.
Volume: 40
Issue: 11
Pages: 1306-1323.e8
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Publication
24736544 | J:212454
First Author: Ho PC
Year: 2014
Journal: Cancer Res
Title: Immune-based antitumor effects of BRAF inhibitors rely on signaling by CD40L and IFNγ.
Volume: 74
Issue: 12
Pages: 3205-17
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Publication
28986383 | J:249341
First Author: Brady DC
Year: 2017
Journal: Cancer Res
Title: Copper Chelation Inhibits BRAFV600E-Driven Melanomagenesis and Counters Resistance to BRAFV600E and MEK1/2 Inhibitors.
Volume: 77
Issue: 22
Pages: 6240-6252
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Publication
18199538 | J:131418
First Author: Yeager N
Year: 2008
Journal: Cancer Res
Title: Mammalian target of rapamycin is the key effector of phosphatidylinositol-3-OH-initiated proliferative signals in the thyroid follicular epithelium.
Volume: 68
Issue: 2
Pages: 444-9
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Publication
31122699 | J:291195
First Author: Zhang SJ
Year: 2019
Journal: Biochem Biophys Res Commun
Title: Schwann cell-specific PTEN and EGFR dysfunctions affect neuromuscular junction development by impairing Agrin signaling and autophagy.
Volume: 515
Issue: 1
Pages: 50-56
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30824837 | J:285318
First Author: Long JE
Year: 2019
Journal: Cell Death Differ
Title: Therapeutic resistance and susceptibility is shaped by cooperative multi-compartment tumor adaptation.
Volume: 26
Issue: 11
Pages: 2416-2429
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8041720 | J:91409
First Author: Kim SH
Year: 1994
Journal: Proc Natl Acad Sci U S A
Title: Expression of wild-type and mutant simian virus 40 large tumor antigens in villus-associated enterocytes of transgenic mice.
Volume: 91
Issue: 15
Pages: 6914-8
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19174523 | J:146290
First Author: Klinakis A
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Igf1r as a therapeutic target in a mouse model of basal-like breast cancer.
Volume: 106
Issue: 7
Pages: 2359-64
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8227147 | J:96717
First Author: Kim SH
Year: 1993
Journal: J Cell Biol
Title: Transgenic mouse models that explore the multistep hypothesis of intestinal neoplasia.
Volume: 123
Issue: 4
Pages: 877-93
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28232723 | J:244933
 
First Author: Ju HQ
Year: 2017
Journal: Nat Commun
Title: Mutant Kras- and p16-regulated NOX4 activation overcomes metabolic checkpoints in development of pancreatic ductal adenocarcinoma.
Volume: 8
Pages: 14437
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Publication
22318779 | J:189130
First Author: Rebocho AP
Year: 2011
Journal: Cancer Discov
Title: New insight puts CRAF in sight as a therapeutic target.
Volume: 1
Issue: 2
Pages: 98-9
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Publication
24402942 | J:209158
First Author: Russo M
Year: 2014
Journal: Cancer Discov
Title: Climbing RAS, the everest of oncogenes.
Volume: 4
Issue: 1
Pages: 19-21
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Publication
39395421 | J:358349
First Author: Ross JL
Year: 2024
Journal: Immunity
Title: Microglia and monocyte-derived macrophages drive progression of pediatric high-grade gliomas and are transcriptionally shaped by histone mutations.
Volume: 57
Issue: 11
Pages: 2669-2687.e6
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Publication
23708211 | J:199111
First Author: Guijarro MV
Year: 2013
Journal: Am J Pathol
Title: Dual Pten/Tp53 suppression promotes sarcoma progression by activating Notch signaling.
Volume: 182
Issue: 6
Pages: 2015-27
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24823640 | J:210591
First Author: Aytes A
Year: 2014
Journal: Cancer Cell
Title: Cross-species regulatory network analysis identifies a synergistic interaction between FOXM1 and CENPF that drives prostate cancer malignancy.
Volume: 25
Issue: 5
Pages: 638-651
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Publication
21754979 | J:174838
First Author: Fomchenko EI
Year: 2011
Journal: PLoS One
Title: Recruited cells can become transformed and overtake PDGF-induced murine gliomas in vivo during tumor progression.
Volume: 6
Issue: 7
Pages: e20605
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Publication
32238882 | J:335346
First Author: Uka R
Year: 2020
Journal: Oncogene
Title: Temporal activation of WNT/β-catenin signaling is sufficient to inhibit SOX10 expression and block melanoma growth.
Volume: 39
Issue: 20
Pages: 4132-4154
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Publication
31685822 | J:281598
First Author: Sun Q
Year: 2019
Journal: Nat Commun
Title: A novel mouse model demonstrates that oncogenic melanocyte stem cells engender melanoma resembling human disease.
Volume: 10
Issue: 1
Pages: 5023
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Publication
26359368 | J:231492
First Author: Garcia-Rendueles ME
Year: 2015
Journal: Cancer Discov
Title: NF2 Loss Promotes Oncogenic RAS-Induced Thyroid Cancers via YAP-Dependent Transactivation of RAS Proteins and Sensitizes Them to MEK Inhibition.
Volume: 5
Issue: 11
Pages: 1178-93
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Publication
34788609 | J:321169
First Author: Taranda J
Year: 2021
Journal: Cell Rep
Title: Combined whole-organ imaging at single-cell resolution and immunohistochemical analysis of prostate cancer and its liver and brain metastases.
Volume: 37
Issue: 7
Pages: 110027
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Publication
30833574 | J:273261
First Author: Hoeman CM
Year: 2019
Journal: Nat Commun
Title: ACVR1 R206H cooperates with H3.1K27M in promoting diffuse intrinsic pontine glioma pathogenesis.
Volume: 10
Issue: 1
Pages: 1023
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Publication
27346348 | J:238518
First Author: Benhamou D
Year: 2016
Journal: Cell Rep
Title: A c-Myc/miR17-92/Pten Axis Controls PI3K-Mediated Positive and Negative Selection in B Cell Development and Reconstitutes CD19 Deficiency.
Volume: 16
Issue: 2
Pages: 419-31
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Publication
30674530 | J:273224
First Author: Beckmann PJ
Year: 2019
Journal: Cancer Res
Title: Sleeping Beauty Insertional Mutagenesis Reveals Important Genetic Drivers of Central Nervous System Embryonal Tumors.
Volume: 79
Issue: 5
Pages: 905-917
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Publication
23150596 | J:192348
First Author: Schutzman JL
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Sprouty genes function in suppression of prostate tumorigenesis.
Volume: 109
Issue: 49
Pages: 20023-8
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