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Search results 2201 to 2300 out of 2728 for Lepr

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Category: Publication
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Type Details Score
Publication
26769046 | J:246378
First Author: Hu W
Year: 2016
Journal: Arterioscler Thromb Vasc Biol
Title: Bone Morphogenic Protein 4-Smad-Induced Upregulation of Platelet-Derived Growth Factor AA Impairs Endothelial Function.
Volume: 36
Issue: 3
Pages: 553-60
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Publication
19651810 | J:154390
First Author: Su D
Year: 2009
Journal: Diabetes
Title: FoxO1 links insulin resistance to proinflammatory cytokine IL-1beta production in macrophages.
Volume: 58
Issue: 11
Pages: 2624-33
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Publication
15793261 | J:109430
First Author: Davis RC
Year: 2005
Journal: Diabetes
Title: Ultrafine mapping of SNPs from mouse strains C57BL/6J, DBA/2J, and C57BLKS/J for loci contributing to diabetes and atherosclerosis susceptibility.
Volume: 54
Issue: 4
Pages: 1191-9
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Publication
21521693 | J:174820
First Author: Flach RJ
Year: 2011
Journal: J Biol Chem
Title: Loss of mitogen-activated protein kinase phosphatase-1 protects from hepatic steatosis by repression of cell death-inducing DNA fragmentation factor A (DFFA)-like effector C (CIDEC)/fat-specific protein 27.
Volume: 286
Issue: 25
Pages: 22195-202
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Publication
21586559 | J:174883
First Author: Peier AM
Year: 2011
Journal: Endocrinology
Title: Effects of peripherally administered neuromedin U on energy and glucose homeostasis.
Volume: 152
Issue: 7
Pages: 2644-54
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Publication
38582490 | J:347881
 
First Author: Pan X
Year: 2024
Journal: Metabolism
Title: Krüppel-like factor 10 protects against metabolic dysfunction-associated steatohepatitis by regulating HNF4α-mediated metabolic pathways.
Volume: 155
Pages: 155909
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Publication
25264246 | J:215526
First Author: Kim-Muller JY
Year: 2014
Journal: Cell Metab
Title: Metabolic inflexibility impairs insulin secretion and results in MODY-like diabetes in triple FoxO-deficient mice.
Volume: 20
Issue: 4
Pages: 593-602
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Publication
23715558 | J:219478
First Author: Velmurugan GV
Year: 2013
Journal: Cardiovasc Res
Title: Defective Nrf2-dependent redox signalling contributes to microvascular dysfunction in type 2 diabetes.
Volume: 100
Issue: 1
Pages: 143-50
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Publication
38538784 | J:349903
First Author: Lu YZ
Year: 2024
Journal: Nature
Title: CGRP sensory neurons promote tissue healing via neutrophils and macrophages.
Volume: 628
Issue: 8008
Pages: 604-611
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Publication
24916066 | J:310292
 
First Author: Niedowicz DM
Year: 2014
Journal: Acta Neuropathol Commun
Title: Obesity and diabetes cause cognitive dysfunction in the absence of accelerated β-amyloid deposition in a novel murine model of mixed or vascular dementia.
Volume: 2
Pages: 64
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Publication
37989315 | J:347516
First Author: Sundaram VK
Year: 2023
Journal: Cell Metab
Title: Adipo-glial signaling mediates metabolic adaptation in peripheral nerve regeneration.
Volume: 35
Issue: 12
Pages: 2136-2152.e9
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Publication
25576055 | J:249436
First Author: Chen Y
Year: 2015
Journal: Diabetes
Title: Enhancement of hypothalamic STAT3 acetylation by nuclear receptor Nur77 dictates leptin sensitivity.
Volume: 64
Issue: 6
Pages: 2069-81
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Publication
26483413 | J:235828
First Author: Ijuin T
Year: 2016
Journal: Mol Cell Biol
Title: Phosphatidylinositol 3,4,5-Trisphosphate Phosphatase SKIP Links Endoplasmic Reticulum Stress in Skeletal Muscle to Insulin Resistance.
Volume: 36
Issue: 1
Pages: 108-18
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Publication
33237428 | J:355607
First Author: Hegyi B
Year: 2020
Journal: Basic Res Cardiol
Title: Hyperglycemia regulates cardiac K(+) channels via O-GlcNAc-CaMKII and NOX2-ROS-PKC pathways.
Volume: 115
Issue: 6
Pages: 71
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Publication
30243722 | J:270296
First Author: Xu L
Year: 2018
Journal: Biochem Biophys Res Commun
Title: DNA-binding activity of STAT3 increased in hypothalamus of DIO mice; the reduction of STAT3 phosphorylation may facilitate leptin signaling.
Volume: 505
Issue: 1
Pages: 229-235
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Publication
34675215 | J:316739
First Author: Qin Y
Year: 2021
Journal: Nat Commun
Title: Macrophage deletion of Noc4l triggers endosomal TLR4/TRIF signal and leads to insulin resistance.
Volume: 12
Issue: 1
Pages: 6121
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Publication
26470784 | J:246551
First Author: Ni R
Year: 2016
Journal: Diabetes
Title: Mitochondrial Calpain-1 Disrupts ATP Synthase and Induces Superoxide Generation in Type 1 Diabetic Hearts: A Novel Mechanism Contributing to Diabetic Cardiomyopathy.
Volume: 65
Issue: 1
Pages: 255-68
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Publication
27039902 | J:235869
First Author: Bensellam M
Year: 2016
Journal: Diabetologia
Title: Hypoxia reduces ER-to-Golgi protein trafficking and increases cell death by inhibiting the adaptive unfolded protein response in mouse beta cells.
Volume: 59
Issue: 7
Pages: 1492-1502
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Publication
19202066 | J:146455
First Author: Kawauchi K
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Loss of p53 enhances catalytic activity of IKKbeta through O-linked beta-N-acetyl glucosamine modification.
Volume: 106
Issue: 9
Pages: 3431-6
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Publication
25205222 | J:219690
First Author: Kim DK
Year: 2014
Journal: Diabetologia
Title: PKB/Akt phosphorylation of ERRγ contributes to insulin-mediated inhibition of hepatic gluconeogenesis.
Volume: 57
Issue: 12
Pages: 2576-85
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Publication
34622154 | J:314446
First Author: Yau B
Year: 2021
Journal: iScience
Title: Proteomic pathways to metabolic disease and type 2 diabetes in the pancreatic islet.
Volume: 24
Issue: 10
Pages: 103099
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Publication
16716264 | J:109651
First Author: Oh KS
Year: 2006
Journal: Biochem Biophys Res Commun
Title: Liver PPARalpha and UCP2 are involved in the regulation of obesity and lipid metabolism by swim training in genetically obese db/db mice.
Volume: 345
Issue: 3
Pages: 1232-9
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Publication
18971923 | J:162711
First Author: Ijaz A
Year: 2009
Journal: Kidney Int
Title: Inhibition of C-jun N-terminal kinase improves insulin sensitivity but worsens albuminuria in experimental diabetes.
Volume: 75
Issue: 4
Pages: 381-8
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Publication
25485909 | J:227947
First Author: Finan B
Year: 2015
Journal: Nat Med
Title: A rationally designed monomeric peptide triagonist corrects obesity and diabetes in rodents.
Volume: 21
Issue: 1
Pages: 27-36
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17267571 | J:117904
First Author: Johnson DR
Year: 2007
Journal: J Neurosci
Title: Acute hypoxia activates the neuroimmune system, which diabetes exacerbates.
Volume: 27
Issue: 5
Pages: 1161-6
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Publication
22581287 | J:187458
First Author: Sheng L
Year: 2012
Journal: Nat Med
Title: NF-κB–inducing kinase (NIK) promotes hyperglycemia and glucose intolerance in obesity by augmenting glucagon action.
Volume: 18
Issue: 6
Pages: 943-9
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Publication
22124464 | J:191536
First Author: Kimura K
Year: 2012
Journal: Diabetes
Title: Endoplasmic reticulum stress inhibits STAT3-dependent suppression of hepatic gluconeogenesis via dephosphorylation and deacetylation.
Volume: 61
Issue: 1
Pages: 61-73
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Publication
15820311 | J:97535
First Author: Yaguchi H
Year: 2005
Journal: Genomics
Title: Identification of candidate genes in the type 2 diabetes modifier locus using expression QTL.
Volume: 85
Issue: 5
Pages: 591-9
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Publication
26552046 | J:228070
First Author: Dominguez Rieg JA
Year: 2016
Journal: Lab Invest
Title: Regulation of intestinal SGLT1 by catestatin in hyperleptinemic type 2 diabetic mice.
Volume: 96
Issue: 1
Pages: 98-111
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Publication
24813890 | J:211797
First Author: Gonçalves GH
Year: 2014
Journal: Cell Rep
Title: Hypothalamic agouti-related peptide neurons and the central melanocortin system are crucial mediators of leptin's antidiabetic actions.
Volume: 7
Issue: 4
Pages: 1093-103
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Publication
11713466 | J:109860
First Author: Gonzalez A
Year: 2001
Journal: Nat Immunol
Title: Damage control, rather than unresponsiveness, effected by protective DX5+ T cells in autoimmune diabetes.
Volume: 2
Issue: 12
Pages: 1117-25
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Publication
21737546 | J:179350
First Author: Cheng H
Year: 2011
Journal: J Am Soc Nephrol
Title: Podocyte COX-2 exacerbates diabetic nephropathy by increasing podocyte (pro)renin receptor expression.
Volume: 22
Issue: 7
Pages: 1240-51
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Publication
27044864 | J:236187
First Author: Uruno A
Year: 2016
Journal: Mol Cell Biol
Title: Nrf2-Mediated Regulation of Skeletal Muscle Glycogen Metabolism.
Volume: 36
Issue: 11
Pages: 1655-72
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Publication
38630048 | J:358643
First Author: Stickel KC
Year: 2024
Journal: Am J Physiol Endocrinol Metab
Title: Mechanisms of spinophilin-dependent pancreas dysregulation in obesity.
Volume: 327
Issue: 2
Pages: E155-E171
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Publication
27358174 | J:249807
First Author: Arab JP
Year: 2017
Journal: Hepatology
Title: Bile acids and nonalcoholic fatty liver disease: Molecular insights and therapeutic perspectives.
Volume: 65
Issue: 1
Pages: 350-362
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Publication
16339484 | J:118064
First Author: Barouch LA
Year: 2006
Journal: Circ Res
Title: Cardiac myocyte apoptosis is associated with increased DNA damage and decreased survival in murine models of obesity.
Volume: 98
Issue: 1
Pages: 119-24
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Publication
17202326 | J:142637
First Author: Sherry CL
Year: 2007
Journal: J Immunol
Title: Augmented lipopolysaccharide-induced TNF-alpha production by peritoneal macrophages in type 2 diabetic mice is dependent on elevated glucose and requires p38 MAPK.
Volume: 178
Issue: 2
Pages: 663-70
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Publication
19363130 | J:150876
First Author: Yang J
Year: 2009
Journal: Am J Physiol Heart Circ Physiol
Title: Feed-forward signaling of TNF-alpha and NF-kappaB via IKK-beta pathway contributes to insulin resistance and coronary arteriolar dysfunction in type 2 diabetic mice.
Volume: 296
Issue: 6
Pages: H1850-8
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Publication
31150422 | J:276464
First Author: Sakurai A
Year: 2019
Journal: PLoS One
Title: Involvement of Elf3 on Smad3 activation-dependent injuries in podocytes and excretion of urinary exosome in diabetic nephropathy.
Volume: 14
Issue: 5
Pages: e0216788
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Publication
33456576 | J:331219
First Author: Sheng J
Year: 2021
Journal: Theranostics
Title: Smad3 deficiency promotes beta cell proliferation and function in db/db mice via restoring Pax6 expression.
Volume: 11
Issue: 6
Pages: 2845-2859
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Publication
24394757 | J:211951
First Author: Crépin D
Year: 2014
Journal: Mol Cell Endocrinol
Title: The over-expression of miR-200a in the hypothalamus of ob/ob mice is linked to leptin and insulin signaling impairment.
Volume: 384
Issue: 1-2
Pages: 1-11
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Publication
29089371 | J:292948
First Author: Wang XX
Year: 2018
Journal: J Am Soc Nephrol
Title: FXR/TGR5 Dual Agonist Prevents Progression of Nephropathy in Diabetes and Obesity.
Volume: 29
Issue: 1
Pages: 118-137
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Publication
27528615 | J:236304
First Author: Chen Q
Year: 2016
Journal: Mol Cell Biol
Title: Functional Differences of Very-Low-Density Lipoprotein Receptor Splice Variants in Regulating Wnt Signaling.
Volume: 36
Issue: 20
Pages: 2645-54
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Publication
16794074 | J:110012
First Author: Qi L
Year: 2006
Journal: Science
Title: TRB3 links the E3 ubiquitin ligase COP1 to lipid metabolism.
Volume: 312
Issue: 5781
Pages: 1763-6
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Publication
27932386 | J:247019
First Author: Liu B
Year: 2017
Journal: Diabetes
Title: Aberrant Expression of FBXO2 Disrupts Glucose Homeostasis Through Ubiquitin-Mediated Degradation of Insulin Receptor in Obese Mice.
Volume: 66
Issue: 3
Pages: 689-698
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Publication
26340929 | J:247018
First Author: Lee JM
Year: 2016
Journal: Diabetes
Title: Insulin-Inducible SMILE Inhibits Hepatic Gluconeogenesis.
Volume: 65
Issue: 1
Pages: 62-73
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Publication
31296846 | J:285944
First Author: Pham DD
Year: 2019
Journal: Cell Death Dis
Title: Caspase-2 and p75 neurotrophin receptor (p75NTR) are involved in the regulation of SREBP and lipid genes in hepatocyte cells.
Volume: 10
Issue: 7
Pages: 537
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Publication
25658689 | J:242398
First Author: Pourhoseini S
Year: 2015
Journal: PLoS One
Title: Upregulation of miR21 and repression of Grhl3 by leptin mediates sinusoidal endothelial injury in experimental nonalcoholic steatohepatitis.
Volume: 10
Issue: 2
Pages: e0116780
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Publication
30171034 | J:265187
 
First Author: Tiefenbach J
Year: 2018
Journal: Dis Model Mech
Title: Idebenone and coenzyme Q10 are novel PPARα/γ ligands, with potential for treatment of fatty liver diseases.
Volume: 11
Issue: 9
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Publication
30464200 | J:269976
First Author: Gadaleta RM
Year: 2018
Journal: Sci Rep
Title: Suppression of Hepatic Bile Acid Synthesis by a non-tumorigenic FGF19 analogue Protects Mice from Fibrosis and Hepatocarcinogenesis.
Volume: 8
Issue: 1
Pages: 17210
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Publication
27721459 | J:346815
 
First Author: Nishizawa H
Year: 2016
Journal: Sci Rep
Title: IGF-I induces senescence of hepatic stellate cells and limits fibrosis in a p53-dependent manner.
Volume: 6
Pages: 34605
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Publication
21145759 | J:167293
First Author: Procaccini C
Year: 2010
Journal: Immunity
Title: An oscillatory switch in mTOR kinase activity sets regulatory T cell responsiveness.
Volume: 33
Issue: 6
Pages: 929-41
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Publication
29866655 | J:265275
 
First Author: Kobayashi M
Year: 2018
Journal: Mol Cell Biol
Title: The RNA Methyltransferase Complex of WTAP, METTL3, and METTL14 Regulates Mitotic Clonal Expansion in Adipogenesis.
Volume: 38
Issue: 16
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17369526 | J:126465
First Author: Choe SS
Year: 2007
Journal: Diabetes
Title: Chronic activation of liver X receptor induces beta-cell apoptosis through hyperactivation of lipogenesis: liver X receptor-mediated lipotoxicity in pancreatic beta-cells.
Volume: 56
Issue: 6
Pages: 1534-43
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Publication
35029277 | J:343025
First Author: Hu Q
Year: 2022
Journal: Diabetes
Title: Obesity-Induced miR-455 Upregulation Promotes Adaptive Pancreatic β-Cell Proliferation Through the CPEB1/CDKN1B Pathway.
Volume: 71
Issue: 3
Pages: 394-411
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Publication
30996080 | J:273800
 
First Author: Peng S
Year: 2019
Journal: Sci Transl Med
Title: Identification of entacapone as a chemical inhibitor of FTO mediating metabolic regulation through FOXO1.
Volume: 11
Issue: 488
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Publication
30807826 | J:281485
 
First Author: Griggs RB
Year: 2019
Journal: Neurobiol Dis
Title: Methylglyoxal and a spinal TRPA1-AC1-Epac cascade facilitate pain in the db/db mouse model of type 2 diabetes.
Volume: 127
Pages: 76-86
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Publication
36943878 | J:353322
First Author: Liang W
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: Peroxisome proliferator-activated receptor-α (PPARα) regulates wound healing and mitochondrial metabolism in the cornea.
Volume: 120
Issue: 13
Pages: e2217576120
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Publication
35164902 | J:327560
   
First Author: Zheng X
Year: 2022
Journal: Elife
Title: Repression of hypoxia-inducible factor-1 contributes to increased mitochondrial reactive oxygen species production in diabetes.
Volume: 11
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16702471 | J:122447
First Author: Asai J
Year: 2006
Journal: Circulation
Title: Topical sonic hedgehog gene therapy accelerates wound healing in diabetes by enhancing endothelial progenitor cell-mediated microvascular remodeling.
Volume: 113
Issue: 20
Pages: 2413-24
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30500562 | J:321852
 
First Author: Son DH
Year: 2019
Journal: Metabolism
Title: FoxO1 regulates leptin-induced mood behavior by targeting tyrosine hydroxylase.
Volume: 91
Pages: 43-52
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19188430 | J:151130
First Author: Narvekar P
Year: 2009
Journal: Diabetes
Title: Liver-specific loss of lipolysis-stimulated lipoprotein receptor triggers systemic hyperlipidemia in mice.
Volume: 58
Issue: 5
Pages: 1040-9
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Publication
25448064 | J:220285
 
First Author: Kapodistria K
Year: 2015
Journal: Mol Cell Endocrinol
Title: Nephrin, a transmembrane protein, is involved in pancreatic beta-cell survival signaling.
Volume: 400
Pages: 112-28
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Publication
33285301 | J:300481
 
First Author: Collier JJ
Year: 2020
Journal: Mol Metab
Title: Pancreatic, but not myeloid-cell, expression of interleukin-1alpha is required for maintenance of insulin secretion and whole body glucose homeostasis.
Volume: 44
Pages: 101140
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Publication
24084737 | J:203991
First Author: Kleinridders A
Year: 2013
Journal: J Clin Invest
Title: Leptin regulation of Hsp60 impacts hypothalamic insulin signaling.
Volume: 123
Issue: 11
Pages: 4667-80
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26059465 | J:247269
First Author: Sreenivasan J
Year: 2015
Journal: Immunology
Title: The thymoprotective function of leptin is indirectly mediated via suppression of obesity.
Volume: 146
Issue: 1
Pages: 122-9
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29311632 | J:260174
First Author: Meakin PJ
Year: 2018
Journal: Sci Rep
Title: Bace1-dependent amyloid processing regulates hypothalamic leptin sensitivity in obese mice.
Volume: 8
Issue: 1
Pages: 55
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Publication
26733203 | J:317940
First Author: Xu W
Year: 2016
Journal: J Biol Chem
Title: Differential Roles of Cell Death-inducing DNA Fragmentation Factor-α-like Effector (CIDE) Proteins in Promoting Lipid Droplet Fusion and Growth in Subpopulations of Hepatocytes.
Volume: 291
Issue: 9
Pages: 4282-93
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Publication
29674655 | J:265724
First Author: Jung SB
Year: 2018
Journal: Nat Commun
Title: Reduced oxidative capacity in macrophages results in systemic insulin resistance.
Volume: 9
Issue: 1
Pages: 1551
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Publication
31393858 | J:290013
   
First Author: Kalliora C
Year: 2019
Journal: JCI Insight
Title: Dual peroxisome-proliferator-activated-receptor-α/γ activation inhibits SIRT1-PGC1α axis and causes cardiac dysfunction.
Volume: 5
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Publication
24595303 | J:212281
First Author: Liu Y
Year: 2014
Journal: Am J Physiol Endocrinol Metab
Title: Anthocyanin increases adiponectin secretion and protects against diabetes-related endothelial dysfunction.
Volume: 306
Issue: 8
Pages: E975-88
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Publication
35067718 | J:327723
 
First Author: Yu Z
Year: 2022
Journal: J Cell Sci
Title: ADAR1 inhibits adipogenesis and obesity by interacting with Dicer to promote the maturation of miR-155-5P.
Volume: 135
Issue: 5
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20643953 | J:163456
First Author: Lam QL
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Leptin signaling maintains B-cell homeostasis via induction of Bcl-2 and Cyclin D1.
Volume: 107
Issue: 31
Pages: 13812-7
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12957148 | J:85594
First Author: Tadayoni R
Year: 2003
Journal: Exp Eye Res
Title: Erythrocyte and leukocyte dynamics in the retinal capillaries of diabetic mice.
Volume: 77
Issue: 4
Pages: 497-504
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12193546 | J:81463
First Author: Ariyasu H
Year: 2002
Journal: Endocrinology
Title: Delayed short-term secretory regulation of ghrelin in obese animals: evidenced by a specific RIA for the active form of ghrelin.
Volume: 143
Issue: 9
Pages: 3341-50
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Publication
21346174 | J:171758
First Author: Kim W
Year: 2011
Journal: Diabetes
Title: Cannabinoids inhibit insulin receptor signaling in pancreatic β-cells.
Volume: 60
Issue: 4
Pages: 1198-209
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Publication
21829168 | J:179942
First Author: Yu X
Year: 2011
Journal: EMBO J
Title: Egr-1 decreases adipocyte insulin sensitivity by tilting PI3K/Akt and MAPK signal balance in mice.
Volume: 30
Issue: 18
Pages: 3754-65
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Publication
17095713 | J:135034
First Author: Bodary PF
Year: 2007
Journal: Arterioscler Thromb Vasc Biol
Title: Leptin regulates neointima formation after arterial injury through mechanisms independent of blood pressure and the leptin receptor/STAT3 signaling pathways involved in energy balance.
Volume: 27
Issue: 1
Pages: 70-6
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Publication
24326423 | J:208371
First Author: Lee SH
Year: 2014
Journal: Am J Physiol Endocrinol Metab
Title: ROCK1 isoform-specific deletion reveals a role for diet-induced insulin resistance.
Volume: 306
Issue: 3
Pages: E332-43
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Publication
28585545 | J:250329
 
First Author: Axelsson AS
Year: 2017
Journal: Nat Commun
Title: Sox5 regulates beta-cell phenotype and is reduced in type 2 diabetes.
Volume: 8
Pages: 15652
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Publication
23760291 | J:282748
First Author: Miyazawa T
Year: 2013
Journal: Kidney Int
Title: Low nitric oxide bioavailability upregulates renal heparin binding EGF-like growth factor expression.
Volume: 84
Issue: 6
Pages: 1176-88
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Publication
26832955 | J:293379
First Author: Shahzad K
Year: 2016
Journal: J Am Soc Nephrol
Title: Caspase-1, but Not Caspase-3, Promotes Diabetic Nephropathy.
Volume: 27
Issue: 8
Pages: 2270-5
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Publication
31624901 | J:282750
First Author: Bensellam M
Year: 2019
Journal: Diabetologia
Title: Metallothionein 1 negatively regulates glucose-stimulated insulin secretion and is differentially expressed in conditions of beta cell compensation and failure in mice and humans.
Volume: 62
Issue: 12
Pages: 2273-2286
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Publication
27412556 | J:240830
 
First Author: Jang H
Year: 2016
Journal: Nat Commun
Title: SREBP1c-CRY1 signalling represses hepatic glucose production by promoting FOXO1 degradation during refeeding.
Volume: 7
Pages: 12180
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