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Search results 2301 to 2400 out of 2570 for Kras

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Categories

Category: Publication
Type Details Score
Publication
First Author: Helmy K
Year: 2012
Journal: PLoS One
Title: Identification of global alteration of translational regulation in glioma in vivo.
Volume: 7
Issue: 10
Pages: e46965
Publication
First Author: Pitter KL
Year: 2011
Journal: PLoS One
Title: Perifosine and CCI 779 co-operate to induce cell death and decrease proliferation in PTEN-intact and PTEN-deficient PDGF-driven murine glioblastoma.
Volume: 6
Issue: 1
Pages: e14545
Publication
First Author: De Boeck A
Year: 2020
Journal: Nat Commun
Title: Glioma-derived IL-33 orchestrates an inflammatory brain tumor microenvironment that accelerates glioma progression.
Volume: 11
Issue: 1
Pages: 4997
Publication
First Author: Chen Z
Year: 2020
Journal: Glia
Title: Genetic driver mutations introduced in identical cell-of-origin in murine glioblastoma reveal distinct immune landscapes but similar response to checkpoint blockade.
Volume: 68
Issue: 10
Pages: 2148-2166
Publication
First Author: Ross JL
Year: 2021
Journal: Brain
Title: Platelet-derived growth factor beta is a potent inflammatory driver in paediatric high-grade glioma.
Volume: 144
Issue: 1
Pages: 53-69
Publication
First Author: Herting CJ
Year: 2017
Journal: Glia
Title: Genetic driver mutations define the expression signature and microenvironmental composition of high-grade gliomas.
Volume: 65
Issue: 12
Pages: 1914-1926
Publication
First Author: Quail DF
Year: 2016
Journal: Science
Title: The tumor microenvironment underlies acquired resistance to CSF-1R inhibition in gliomas.
Volume: 352
Issue: 6288
Pages: aad3018
Publication
First Author: Yang F
Year: 2024
Journal: Sci Adv
Title: An immunosuppressive vascular niche drives macrophage polarization and immunotherapy resistance in glioblastoma.
Volume: 10
Issue: 9
Pages: eadj4678
Publication  
First Author: Chen Z
Year: 2023
Journal: J Clin Invest
Title: A paracrine circuit of IL-1β/IL-1R1 between myeloid and tumor cells drives genotype-dependent glioblastoma progression.
Volume: 133
Issue: 22
Publication
First Author: Chen Z
Year: 2017
Journal: Cancer Res
Title: Cellular and Molecular Identity of Tumor-Associated Macrophages in Glioblastoma.
Volume: 77
Issue: 9
Pages: 2266-2278
Publication
First Author: Buonfiglioli A
Year: 2019
Journal: Cell Rep
Title: let-7 MicroRNAs Regulate Microglial Function and Suppress Glioma Growth through Toll-Like Receptor 7.
Volume: 29
Issue: 11
Pages: 3460-3471.e7
Publication
First Author: Nowak DG
Year: 2015
Journal: Cancer Discov
Title: MYC Drives Pten/Trp53-Deficient Proliferation and Metastasis due to IL6 Secretion and AKT Suppression via PHLPP2.
Volume: 5
Issue: 6
Pages: 636-51
Publication
First Author: Brady NJ
Year: 2021
Journal: Nat Commun
Title: Temporal evolution of cellular heterogeneity during the progression to advanced AR-negative prostate cancer.
Volume: 12
Issue: 1
Pages: 3372
Publication
First Author: Das SK
Year: 2016
Journal: Oncotarget
Title: Knockout of MDA-9/Syntenin (SDCBP) expression in the microenvironment dampens tumor-supporting inflammation and inhibits melanoma metastasis.
Volume: 7
Issue: 30
Pages: 46848-46861
Publication
First Author: Chessa TAM
Year: 2023
Journal: Mol Cell
Title: PLEKHS1 drives PI3Ks and remodels pathway homeostasis in PTEN-null prostate.
Volume: 83
Issue: 16
Pages: 2991-3009.e13
Publication
First Author: Palmer CJ
Year: 2014
Journal: Cancer Res
Title: Zfx facilitates tumorigenesis caused by activation of the Hedgehog pathway.
Volume: 74
Issue: 20
Pages: 5914-24
Publication
First Author: Li G
Year: 2020
Journal: Cancer Res
Title: KDM5B Is Essential for the Hyperactivation of PI3K/AKT Signaling in Prostate Tumorigenesis.
Volume: 80
Issue: 21
Pages: 4633-4643
Publication
First Author: Gao D
Year: 2016
Journal: PLoS One
Title: A Tmprss2-CreERT2 Knock-In Mouse Model for Cancer Genetic Studies on Prostate and Colon.
Volume: 11
Issue: 8
Pages: e0161084
Publication
First Author: Morris JP 4th
Year: 2009
Journal: Cancer Cell
Title: It's a free for all--insulin-positive cells join the group of potential progenitors for pancreatic ductal adenocarcinoma.
Volume: 16
Issue: 5
Pages: 359-61
Publication
First Author: Barbacid M
Year: 2012
Journal: Cancer Cell
Title: Opening a new GATAway for treating KRAS-driven lung tumors.
Volume: 21
Issue: 5
Pages: 598-600
Publication
First Author: Perera RM
Year: 2012
Journal: Cancer Cell
Title: Ready, set, go: the EGF receptor at the pancreatic cancer starting line.
Volume: 22
Issue: 3
Pages: 281-2
Publication
First Author: Vonderheide RH
Year: 2014
Journal: Cancer Cell
Title: Tumor-promoting inflammatory networks in pancreatic neoplasia: another reason to loathe Kras.
Volume: 25
Issue: 5
Pages: 553-4
Publication
First Author: Luo F
Year: 2007
Journal: Oncogene
Title: Conditional expression of mutated K-ras accelerates intestinal tumorigenesis in Msh2-deficient mice.
Volume: 26
Issue: 30
Pages: 4415-27
Publication
First Author: Sullivan MR
Year: 2019
Journal: Cell Metab
Title: Increased Serine Synthesis Provides an Advantage for Tumors Arising in Tissues Where Serine Levels Are Limiting.
Volume: 29
Issue: 6
Pages: 1410-1421.e4
Publication
First Author: Hambardzumyan D
Year: 2009
Journal: Transl Oncol
Title: Modeling Adult Gliomas Using RCAS/t-va Technology.
Volume: 2
Issue: 2
Pages: 89-95
Publication
First Author: Ozawa T
Year: 2018
Journal: Cell Rep
Title: A De Novo Mouse Model of C11orf95-RELA Fusion-Driven Ependymoma Identifies Driver Functions in Addition to NF-κB.
Volume: 23
Issue: 13
Pages: 3787-3797
Publication
First Author: Hu X
Year: 2005
Journal: Neoplasia
Title: mTOR promotes survival and astrocytic characteristics induced by Pten/AKT signaling in glioblastoma.
Volume: 7
Issue: 4
Pages: 356-68
Publication
First Author: Ozawa T
Year: 2014
Journal: Cancer Cell
Title: Most human non-GCIMP glioblastoma subtypes evolve from a common proneural-like precursor glioma.
Volume: 26
Issue: 2
Pages: 288-300
Publication
First Author: Zabala-Letona A
Year: 2017
Journal: Nature
Title: mTORC1-dependent AMD1 regulation sustains polyamine metabolism in prostate cancer.
Volume: 547
Issue: 7661
Pages: 109-113
Publication
First Author: Hieronymus H
Year: 2017
Journal: Nat Commun
Title: Deletion of 3p13-14 locus spanning FOXP1 to SHQ1 cooperates with PTEN loss in prostate oncogenesis.
Volume: 8
Issue: 1
Pages: 1081
Publication
First Author: Resnick-Silverman L
Year: 2015
Journal: Cancer Discov
Title: Two Faces of SIVA.
Volume: 5
Issue: 6
Pages: 581-3
Publication
First Author: Yuan M
Year: 2022
Journal: Nat Cancer
Title: Cancer-associated fibroblasts employ NUFIP1-dependent autophagy to secrete nucleosides and support pancreatic tumor growth.
Volume: 3
Issue: 8
Pages: 945-960
Publication
First Author: International Cancer Genome Consortium PedBrain Tumor Project.
Year: 2016
Journal: Nat Med
Title: Recurrent MET fusion genes represent a drug target in pediatric glioblastoma.
Volume: 22
Issue: 11
Pages: 1314-1320
Publication
First Author: Huang Y
Year: 2017
Journal: J Clin Invest
Title: A proangiogenic signaling axis in myeloid cells promotes malignant progression of glioma.
Volume: 127
Issue: 5
Pages: 1826-1838
Publication
First Author: Yang Z
Year: 2017
Journal: Dis Model Mech
Title: Stromal hedgehog signaling maintains smooth muscle and hampers micro-invasive prostate cancer.
Volume: 10
Issue: 1
Pages: 39-52
Publication
First Author: Rolf J
Year: 2010
Journal: J Immunol
Title: Phosphoinositide 3-kinase activity in T cells regulates the magnitude of the germinal center reaction.
Volume: 185
Issue: 7
Pages: 4042-52
Publication
First Author: Yang CS
Year: 2017
Journal: Prostate
Title: The protein kinase C super-family member PKN is regulated by mTOR and influences differentiation during prostate cancer progression.
Volume: 77
Issue: 15
Pages: 1452-1467
Publication  
First Author: Lefebure M
Year: 2017
Journal: Nat Commun
Title: Genomic characterisation of Eμ-Myc mouse lymphomas identifies Bcor as a Myc co-operative tumour-suppressor gene.
Volume: 8
Pages: 14581
Publication
First Author: Morris JP 4th
Year: 2010
Journal: Nat Rev Cancer
Title: KRAS, Hedgehog, Wnt and the twisted developmental biology of pancreatic ductal adenocarcinoma.
Volume: 10
Issue: 10
Pages: 683-95
Publication
First Author: Chen R
Year: 2013
Journal: Cancer Discov
Title: Two is better than one: combining IGF1R and MEK blockade as a promising novel treatment strategy against KRAS-mutant lung cancer.
Volume: 3
Issue: 5
Pages: 491-3
Publication
First Author: Drosten M
Year: 2020
Journal: Cancer Cell
Title: Targeting the MAPK Pathway in KRAS-Driven Tumors.
Volume: 37
Issue: 4
Pages: 543-550
Publication  
First Author: Lee JS
Year: 2019
Journal: EBioMedicine
Title: Loss of SLC25A11 causes suppression of NSCLC and melanoma tumor formation.
Volume: 40
Pages: 184-197
Publication
First Author: Sluse FE
Year: 1973
Journal: Eur J Biochem
Title: Mechanism of the exchanges catalysed by the oxoglutarate translocator of rat-heart mitochondria. Kinetics of the external-product inhibition.
Volume: 32
Issue: 2
Pages: 283-91
Publication
First Author: Yuan Y
Year: 2022
Journal: Sci Adv
Title: α-Ketoglutaric acid ameliorates hyperglycemia in diabetes by inhibiting hepatic gluconeogenesis via serpina1e signaling.
Volume: 8
Issue: 18
Pages: eabn2879
Publication
First Author: Marazioti A
Year: 2018
Journal: Nat Commun
Title: Myeloid-derived interleukin-1β drives oncogenic KRAS-NF-κΒ addiction in malignant pleural effusion.
Volume: 9
Issue: 1
Pages: 672
Publication
First Author: Lim KH
Year: 2008
Journal: Nature
Title: Tumour maintenance is mediated by eNOS.
Volume: 452
Issue: 7187
Pages: 646-9
Publication
First Author: Konstantinidou G
Year: 2013
Journal: Cancer Discov
Title: RHOA-FAK is a required signaling axis for the maintenance of KRAS-driven lung adenocarcinomas.
Volume: 3
Issue: 4
Pages: 444-57
Publication
First Author: Rajbhandari N
Year: 2017
Journal: Cell Rep
Title: Autocrine IGF1 Signaling Mediates Pancreatic Tumor Cell Dormancy in the Absence of Oncogenic Drivers.
Volume: 18
Issue: 9
Pages: 2243-2255
Publication
First Author: Bu W
Year: 2023
Journal: Sci Adv
Title: Efficient cancer modeling through CRISPR-Cas9/HDR-based somatic precision gene editing in mice.
Volume: 9
Issue: 19
Pages: eade0059
Publication
First Author: Ni H
Year: 2019
Journal: Carcinogenesis
Title: ErbB4 acts as a suppressor in colitis and its associated carcinoma by negatively regulating cholesterol metabolism.
Volume: 40
Issue: 5
Pages: 680-686
Publication      
First Author: Ely ZA
Year: 2023
Journal: Nat Biotechnol
Title: A prime editor mouse to model a broad spectrum of somatic mutations in vivo.
Publication
First Author: Thomas KR
Year: 2022
Journal: Leukemia
Title: Activated interleukin-7 receptor signaling drives B-cell acute lymphoblastic leukemia in mice.
Volume: 36
Issue: 1
Pages: 42-57
Publication
First Author: Akula MK
Year: 2016
Journal: Nat Immunol
Title: Control of the innate immune response by the mevalonate pathway.
Volume: 17
Issue: 8
Pages: 922-9
Publication    
First Author: Spella M
Year: 2019
Journal: Elife
Title: Club cells form lung adenocarcinomas and maintain the alveoli of adult mice.
Volume: 8
Publication
First Author: Rowald K
Year: 2016
Journal: Cell Rep
Title: Negative Selection and Chromosome Instability Induced by Mad2 Overexpression Delay Breast Cancer but Facilitate Oncogene-Independent Outgrowth.
Volume: 15
Issue: 12
Pages: 2679-91
Publication
First Author: Edmonds MD
Year: 2016
Journal: J Clin Invest
Title: MicroRNA-31 initiates lung tumorigenesis and promotes mutant KRAS-driven lung cancer.
Volume: 126
Issue: 1
Pages: 349-64
Publication
First Author: Sotillo R
Year: 2010
Journal: Nature
Title: Mad2-induced chromosome instability leads to lung tumour relapse after oncogene withdrawal.
Volume: 464
Issue: 7287
Pages: 436-40
Publication    
First Author: Zhang Y
Year: 2017
Journal: Elife
Title: Epithelial-Myeloid cell crosstalk regulates acinar cell plasticity and pancreatic remodeling in mice.
Volume: 6
Publication
First Author: González-Sánchez E
Year: 2013
Journal: PLoS One
Title: Lkb1 loss promotes tumor progression of BRAF(V600E)-induced lung adenomas.
Volume: 8
Issue: 6
Pages: e66933
Publication
First Author: Holmen SL
Year: 2005
Journal: Cancer Res
Title: Essential role for Ras signaling in glioblastoma maintenance.
Volume: 65
Issue: 18
Pages: 8250-5
Publication
First Author: VanBrocklin MW
Year: 2010
Journal: Pigment Cell Melanoma Res
Title: Targeted delivery of NRASQ61R and Cre-recombinase to post-natal melanocytes induces melanoma in Ink4a/Arflox/lox mice.
Volume: 23
Issue: 4
Pages: 531-41
Publication
First Author: Kim YE
Year: 2023
Journal: Cell Rep
Title: Reversibility and developmental neuropathology of linear nevus sebaceous syndrome caused by dysregulation of the RAS pathway.
Volume: 42
Issue: 1
Pages: 112003
Publication
First Author: Morishita M
Year: 2021
Journal: Genes Cells
Title: Characterization of mouse embryonic fibroblasts derived from Rassf6 knockout mice shows the implication of Rassf6 in the regulation of NF-κB signaling.
Volume: 26
Issue: 12
Pages: 999-1013
Publication
First Author: Xu J
Year: 2012
Journal: Blood
Title: Inhibiting the palmitoylation/depalmitoylation cycle selectively reduces the growth of hematopoietic cells expressing oncogenic Nras.
Volume: 119
Issue: 4
Pages: 1032-5
Publication
First Author: Wong CE
Year: 2013
Journal: Genes Dev
Title: Inflammation and Hras signaling control epithelial-mesenchymal transition during skin tumor progression.
Volume: 27
Issue: 6
Pages: 670-82
Publication
First Author: Wang L
Year: 2015
Journal: Genes Dev
Title: ATDC induces an invasive switch in KRAS-induced pancreatic tumorigenesis.
Volume: 29
Issue: 2
Pages: 171-83
Publication  
First Author: Cha DJ
Year: 2015
Journal: Elife
Title: KRAS-dependent sorting of miRNA to exosomes.
Volume: 4
Pages: e07197
Publication
First Author: Erami Z
Year: 2016
Journal: Cell Rep
Title: Intravital FRAP Imaging using an E-cadherin-GFP Mouse Reveals Disease- and Drug-Dependent Dynamic Regulation of Cell-Cell Junctions in Live Tissue.
Volume: 14
Issue: 1
Pages: 152-167
Publication
First Author: Bastea LI
Year: 2024
Journal: Nat Commun
Title: Coxsackievirus and adenovirus receptor expression facilitates enteroviral infections to drive the development of pancreatic cancer.
Volume: 15
Issue: 1
Pages: 10547
Publication
First Author: Hyrenius-Wittsten A
Year: 2018
Journal: Nat Commun
Title: De novo activating mutations drive clonal evolution and enhance clonal fitness in KMT2A-rearranged leukemia.
Volume: 9
Issue: 1
Pages: 1770
Publication
First Author: Li S
Year: 2018
Journal: Nat Rev Cancer
Title: A model for RAS mutation patterns in cancers: finding the sweet spot.
Volume: 18
Issue: 12
Pages: 767-777
Publication
First Author: Patra KC
Year: 2018
Journal: Nat Cell Biol
Title: Mutant GNAS drives pancreatic tumourigenesis by inducing PKA-mediated SIK suppression and reprogramming lipid metabolism.
Volume: 20
Issue: 7
Pages: 811-822
Publication    
First Author: Adams CR
Year: 2019
Journal: Elife
Title: Transcriptional control of subtype switching ensures adaptation and growth of pancreatic cancer.
Volume: 8
Publication
First Author: Hishida T
Year: 2019
Journal: Protein Cell
Title: Mutations in foregut SOX2+ cells induce efficient proliferation via CXCR2 pathway.
Volume: 10
Issue: 7
Pages: 485-495
Publication
First Author: Escobar-Hoyos LF
Year: 2020
Journal: Cancer Cell
Title: Altered RNA Splicing by Mutant p53 Activates Oncogenic RAS Signaling in Pancreatic Cancer.
Volume: 38
Issue: 2
Pages: 198-211.e8
Publication
First Author: Pickering KA
Year: 2021
Journal: Nat Commun
Title: A RAC-GEF network critical for early intestinal tumourigenesis.
Volume: 12
Issue: 1
Pages: 56
Publication  
First Author: Munagala R
Year: 2021
Journal: Cancer Lett
Title: Exosome-mediated delivery of RNA and DNA for gene therapy.
Volume: 505
Pages: 58-72
Publication      
First Author: Pitarresi JR
Year: 2021
Journal: Cancer Discov
Title: PTHrP drives pancreatic cancer growth and metastasis and reveals a new therapeutic vulnerability.
Publication
First Author: Mao Y
Year: 2017
Journal: Oncotarget
Title: Role and regulation of Yap in KrasG12D-induced lung cancer.
Volume: 8
Issue: 67
Pages: 110877-110889
Publication  
First Author: Castel P
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: RAS interaction with Sin1 is dispensable for mTORC2 assembly and activity.
Volume: 118
Issue: 33
Publication
First Author: Zhong C
Year: 2020
Journal: Cancer Sci
Title: ZNF251 promotes the progression of lung cancer by activating ERK signaling.
Volume: 111
Issue: 9
Pages: 3236-3244
Publication
First Author: Sinkevicius KW
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Neurotrophin receptor TrkB promotes lung adenocarcinoma metastasis.
Volume: 111
Issue: 28
Pages: 10299-304
Publication
First Author: Venkatanarayan A
Year: 2022
Journal: Cell Rep
Title: CRAF dimerization with ARAF regulates KRAS-driven tumor growth.
Volume: 38
Issue: 6
Pages: 110351
Publication
First Author: Liu Y
Year: 2022
Journal: Nat Commun
Title: Rapid acceleration of KRAS-mutant pancreatic carcinogenesis via remodeling of tumor immune microenvironment by PPARδ.
Volume: 13
Issue: 1
Pages: 2665
Publication
First Author: Hall AE
Year: 2022
Journal: Nat Commun
Title: RNA splicing is a key mediator of tumour cell plasticity and a therapeutic vulnerability in colorectal cancer.
Volume: 13
Issue: 1
Pages: 2791
Publication  
First Author: Jiang H
Year: 2022
Journal: J Exp Med
Title: Ferrous iron-activatable drug conjugate achieves potent MAPK blockade in KRAS-driven tumors.
Volume: 219
Issue: 4
Publication  
First Author: Xie Y
Year: 2023
Journal: JCI Insight
Title: SETD2 regulates chromatin accessibility and transcription to suppress lung tumorigenesis.
Volume: 8
Issue: 4
Publication
First Author: Feng Z
Year: 2024
Journal: Nat Cancer
Title: An in vitro-transcribed circular RNA targets the mitochondrial inner membrane cardiolipin to ablate EIF4G2(+)/PTBP1(+) pan-adenocarcinoma.
Volume: 5
Issue: 1
Pages: 30-46
Publication
First Author: Fu J
Year: 2024
Journal: Nat Commun
Title: Nardilysin-regulated scission mechanism activates polo-like kinase 3 to suppress the development of pancreatic cancer.
Volume: 15
Issue: 1
Pages: 3149
Publication
First Author: Janas ML
Year: 2008
Journal: J Immunol
Title: The effect of deleting p110delta on the phenotype and function of PTEN-deficient B cells.
Volume: 180
Issue: 2
Pages: 739-46
Publication  
First Author: Grego-Bessa J
Year: 2016
Journal: Elife
Title: The tumor suppressor PTEN and the PDK1 kinase regulate formation of the columnar neural epithelium.
Volume: 5
Pages: e12034
Publication
First Author: Huse JT
Year: 2009
Journal: Brain Pathol
Title: Genetically engineered mouse models of brain cancer and the promise of preclinical testing.
Volume: 19
Issue: 1
Pages: 132-43
Publication
First Author: Hollern DP
Year: 2019
Journal: Breast Cancer Res Treat
Title: A mouse model featuring tissue-specific deletion of p53 and Brca1 gives rise to mammary tumors with genomic and transcriptomic similarities to human basal-like breast cancer.
Volume: 174
Issue: 1
Pages: 143-155
Publication  
First Author: Andrijes R
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Tetraspanin 6 is a regulator of carcinogenesis in colorectal cancer.
Volume: 118
Issue: 39
Publication
First Author: Raposo TP
Year: 2020
Journal: Int J Exp Pathol
Title: Tensin4 (TNS4) is upregulated by Wnt signalling in adenomas in multiple intestinal neoplasia (Min) mice.
Volume: 101
Issue: 3-4
Pages: 80-86
Publication    
First Author: Gbenedio OM
Year: 2019
Journal: JCI Insight
Title: RasGRP1 is a potential biomarker to stratify anti-EGFR therapy response in colorectal cancer.
Volume: 5
Publication
First Author: Lee D
Year: 2009
Journal: J Clin Invest
Title: Tumor-specific apoptosis caused by deletion of the ERBB3 pseudo-kinase in mouse intestinal epithelium.
Volume: 119
Issue: 9
Pages: 2702-13
Publication
First Author: Reilly KM
Year: 2006
Journal: Cancer Res
Title: An imprinted locus epistatically influences Nstr1 and Nstr2 to control resistance to nerve sheath tumors in a neurofibromatosis type 1 mouse model.
Volume: 66
Issue: 1
Pages: 62-8
Publication
First Author: Lyustikman Y
Year: 2008
Journal: Neoplasia
Title: Constitutive activation of Raf-1 induces glioma formation in mice.
Volume: 10
Issue: 5
Pages: 501-10
Publication
First Author: Yang G
Year: 2007
Journal: Cancer Res
Title: Loss of xeroderma pigmentosum C (Xpc) enhances melanoma photocarcinogenesis in Ink4a-Arf-deficient mice.
Volume: 67
Issue: 12
Pages: 5649-57