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Search results 2301 to 2400 out of 2663 for Psen1

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Category: Publication
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Type Details Score
Publication
19661615 | J:274986
First Author: Moreno-Gonzalez I
Year: 2009
Journal: J Alzheimers Dis
Title: Extracellular amyloid-beta and cytotoxic glial activation induce significant entorhinal neuron loss in young PS1(M146L)/APP(751SL) mice.
Volume: 18
Issue: 4
Pages: 755-76
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Publication
24440715 | J:208794
First Author: Minett MS
Year: 2014
Journal: Cell Rep
Title: Pain without nociceptors? Nav1.7-independent pain mechanisms.
Volume: 6
Issue: 2
Pages: 301-12
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Publication
28566429 | J:249633
 
First Author: Shi Q
Year: 2017
Journal: Sci Transl Med
Title: Complement C3 deficiency protects against neurodegeneration in aged plaque-rich APP/PS1 mice.
Volume: 9
Issue: 392
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Publication
25731615 | J:221193
First Author: Kamphuis W
Year: 2015
Journal: Glia
Title: GFAP and vimentin deficiency alters gene expression in astrocytes and microglia in wild-type mice and changes the transcriptional response of reactive glia in mouse model for Alzheimer's disease.
Volume: 63
Issue: 6
Pages: 1036-56
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Publication
23831297 | J:200093
First Author: Yang Y
Year: 2013
Journal: Am J Pathol
Title: APOE3, but not APOE4, bone marrow transplantation mitigates behavioral and pathological changes in a mouse model of Alzheimer disease.
Volume: 183
Issue: 3
Pages: 905-17
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Publication
24305823 | J:204149
First Author: Kanekiyo T
Year: 2013
Journal: J Neurosci
Title: Neuronal clearance of amyloid-β by endocytic receptor LRP1.
Volume: 33
Issue: 49
Pages: 19276-83
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Publication
11709540 | J:72987
First Author: Lesuisse C
Year: 2001
Journal: Hum Mol Genet
Title: Hyper-expression of human apolipoprotein E4 in astroglia and neurons does not enhance amyloid deposition in transgenic mice.
Volume: 10
Issue: 22
Pages: 2525-37
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Publication
19036982 | J:142501
First Author: Dodson SE
Year: 2008
Journal: J Neurosci
Title: Loss of LR11/SORLA enhances early pathology in a mouse model of amyloidosis: evidence for a proximal role in Alzheimer's disease.
Volume: 28
Issue: 48
Pages: 12877-86
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Publication
25797218 | J:335464
 
First Author: Ettcheto M
Year: 2015
Journal: Exp Gerontol
Title: Hypercholesterolemia and neurodegeneration. Comparison of hippocampal phenotypes in LDLr knockout and APPswe/PS1dE9 mice.
Volume: 65
Pages: 69-78
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Publication
25912193 | J:230333
 
First Author: Gao L
Year: 2015
Journal: Exp Eye Res
Title: Neuroprotective effect of memantine on the retinal ganglion cells of APPswe/PS1ΔE9 mice and its immunomodulatory mechanisms.
Volume: 135
Pages: 47-58
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Publication
21755005 | J:174945
First Author: Katsouri L
Year: 2011
Journal: PLoS One
Title: Lack of LDL receptor enhances amyloid deposition and decreases glial response in an Alzheimer's disease mouse model.
Volume: 6
Issue: 7
Pages: e21880
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Publication
29444819 | J:259749
First Author: Hu X
Year: 2018
Journal: J Exp Med
Title: BACE1 deletion in the adult mouse reverses preformed amyloid deposition and improves cognitive functions.
Volume: 215
Issue: 3
Pages: 927-940
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Publication
38326859 | J:350706
First Author: Daily KP
Year: 2024
Journal: Alzheimers Res Ther
Title: DNA hypomethylation promotes the expression of CASPASE-4 which exacerbates inflammation and amyloid-β deposition in Alzheimer's disease.
Volume: 16
Issue: 1
Pages: 29
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Publication
23283348 | J:193915
First Author: Carlo AS
Year: 2013
Journal: J Neurosci
Title: The pro-neurotrophin receptor sortilin is a major neuronal apolipoprotein E receptor for catabolism of amyloid-β peptide in the brain.
Volume: 33
Issue: 1
Pages: 358-70
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Publication
34247441 | J:310745
First Author: Du S
Year: 2021
Journal: Aging Cell
Title: FoxO3 deficiency in cortical astrocytes leads to impaired lipid metabolism and aggravated amyloid pathology.
Volume: 20
Issue: 8
Pages: e13432
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38878650 | J:359210
 
First Author: Kong Y
Year: 2024
Journal: J Neurol Sci
Title: In vivo reactive astrocyte imaging using [(18)F]SMBT-1 in tauopathy and familial Alzheimer's disease mouse models: A multi-tracer study.
Volume: 462
Pages: 123079
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Publication
25069841 | J:232466
First Author: Polito VA
Year: 2014
Journal: EMBO Mol Med
Title: Selective clearance of aberrant tau proteins and rescue of neurotoxicity by transcription factor EB.
Volume: 6
Issue: 9
Pages: 1142-60
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Publication
34131105 | J:308032
First Author: Pérez-Sisqués L
Year: 2021
Journal: Cell Death Dis
Title: RTP801/REDD1 contributes to neuroinflammation severity and memory impairments in Alzheimer's disease.
Volume: 12
Issue: 6
Pages: 616
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Publication
39375474 | J:355028
First Author: Patel AA
Year: 2024
Journal: Sci Rep
Title: Ex vivo propagation of synaptically-evoked cortical depolarizations in a mouse model of Alzheimer's disease at 20 Hz, 40 Hz, or 83 Hz.
Volume: 14
Issue: 1
Pages: 23365
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Publication
37642942 | J:347913
 
First Author: Ralvenius WT
Year: 2023
Journal: J Exp Med
Title: A novel molecular class that recruits HDAC/MECP2 complexes to PU.1 motifs reduces neuroinflammation.
Volume: 220
Issue: 11
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Publication
38433923 | J:347916
First Author: Liu P
Year: 2024
Journal: iScience
Title: Aβ∗56 is a stable oligomer that impairs memory function in mice.
Volume: 27
Issue: 3
Pages: 109239
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Publication
31076275 | J:276144
First Author: Adaikkan C
Year: 2019
Journal: Neuron
Title: Gamma Entrainment Binds Higher-Order Brain Regions and Offers Neuroprotection.
Volume: 102
Issue: 5
Pages: 929-943.e8
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Publication
36180790 | J:341009
First Author: Colombo G
Year: 2022
Journal: Nat Neurosci
Title: A tool for mapping microglial morphology, morphOMICs, reveals brain-region and sex-dependent phenotypes.
Volume: 25
Issue: 10
Pages: 1379-1393
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Publication
37917195 | J:348194
 
First Author: Matrongolo MJ
Year: 2023
Journal: J Clin Invest
Title: Piezo1 agonist restores meningeal lymphatic vessels, drainage, and brain-CSF perfusion in craniosynostosis and aged mice.
Volume: 134
Issue: 4
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28434692 | J:244833
 
First Author: Yin Z
Year: 2017
Journal: Neurobiol Aging
Title: Immune hyperreactivity of Aβ plaque-associated microglia in Alzheimer's disease.
Volume: 55
Pages: 115-122
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Publication
33277246 | J:299756
 
First Author: Zhang X
Year: 2020
Journal: Sci Adv
Title: Oligodendroglial glycolytic stress triggers inflammasome activation and neuropathology in Alzheimer's disease.
Volume: 6
Issue: 49
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Publication
35025109 | J:324342
First Author: Hohsfield LA
Year: 2022
Journal: Glia
Title: MAC2 is a long-lasting marker of peripheral cell infiltrates into the mouse CNS after bone marrow transplantation and coronavirus infection.
Volume: 70
Issue: 5
Pages: 875-891
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Publication
30804789 | J:281381
 
First Author: Ano Y
Year: 2019
Journal: Front Pharmacol
Title: Iso-α-Acids, Bitter Components in Beer, Suppress Inflammatory Responses and Attenuate Neural Hyperactivation in the Hippocampus.
Volume: 10
Pages: 81
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Publication
37759260 | J:348213
First Author: Wright AL
Year: 2023
Journal: Mol Neurodegener
Title: The Q/R editing site of AMPA receptor GluA2 subunit acts as an epigenetic switch regulating dendritic spines, neurodegeneration and cognitive deficits in Alzheimer's disease.
Volume: 18
Issue: 1
Pages: 65
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Publication
39087029 | J:358640
 
First Author: Antila S
Year: 2024
Journal: Nat Cardiovasc Res
Title: Sustained meningeal lymphatic vessel atrophy or expansion does not alter Alzheimer's disease-related amyloid pathology.
Volume: 3
Pages: 474-491
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35142046 | J:350174
First Author: Claes C
Year: 2022
Journal: Alzheimers Dement
Title: The P522R protective variant of PLCG2 promotes the expression of antigen presentation genes by human microglia in an Alzheimer's disease mouse model.
Volume: 18
Issue: 10
Pages: 1765-1778
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Publication
38164158 | J:344429
First Author: Um JH
Year: 2024
Journal: Theranostics
Title: Selective induction of Rab9-dependent alternative mitophagy using a synthetic derivative of isoquinoline alleviates mitochondrial dysfunction and cognitive deficits in Alzheimer's disease models.
Volume: 14
Issue: 1
Pages: 56-74
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Publication
30741718 | J:295526
First Author: Tachibana M
Year: 2019
Journal: J Clin Invest
Title: APOE4-mediated amyloid-β pathology depends on its neuronal receptor LRP1.
Volume: 129
Issue: 3
Pages: 1272-1277
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Publication
18304698 | J:152955
First Author: Oh ES
Year: 2009
Journal: Neurobiol Aging
Title: Amyloid precursor protein increases cortical neuron size in transgenic mice.
Volume: 30
Issue: 8
Pages: 1238-44
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Publication
19551139 | J:150191
First Author: Turdi S
Year: 2009
Journal: PLoS One
Title: Cardiomyocyte contractile dysfunction in the APPswe/PS1dE9 mouse model of Alzheimer's disease.
Volume: 4
Issue: 6
Pages: e6033
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Publication
22542680 | J:192436
 
First Author: Cai Y
Year: 2012
Journal: Neuroscience
Title: An age-related axon terminal pathology around the first olfactory relay that involves amyloidogenic protein overexpression without plaque formation.
Volume: 215
Pages: 160-73
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Publication
20092570 | J:157228
First Author: Zhang XM
Year: 2009
Journal: Eur J Neurosci
Title: Beta-secretase-1 elevation in transgenic mouse models of Alzheimer's disease is associated with synaptic/axonal pathology and amyloidogenesis: implications for neuritic plaque development.
Volume: 30
Issue: 12
Pages: 2271-83
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Publication
18987201 | J:143198
First Author: Jimenez S
Year: 2008
Journal: J Neurosci
Title: Inflammatory response in the hippocampus of PS1M146L/APP751SL mouse model of Alzheimer's disease: age-dependent switch in the microglial phenotype from alternative to classic.
Volume: 28
Issue: 45
Pages: 11650-61
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Publication
16023262 | J:108853
First Author: Delatour B
Year: 2006
Journal: Neurobiol Aging
Title: In vivo MRI and histological evaluation of brain atrophy in APP/PS1 transgenic mice.
Volume: 27
Issue: 6
Pages: 835-47
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Publication
20413859 | J:274006
First Author: Baglietto-Vargas D
Year: 2010
Journal: J Alzheimers Dis
Title: Calretinin interneurons are early targets of extracellular amyloid-beta pathology in PS1/AbetaPP Alzheimer mice hippocampus.
Volume: 21
Issue: 1
Pages: 119-32
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Publication
16271420 | J:114486
First Author: Ramos B
Year: 2006
Journal: Neurobiol Aging
Title: Early neuropathology of somatostatin/NPY GABAergic cells in the hippocampus of a PS1xAPP transgenic model of Alzheimer's disease.
Volume: 27
Issue: 11
Pages: 1658-72
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Publication
32901091 | J:296147
First Author: Fernandez-Valenzuela JJ
Year: 2020
Journal: Sci Rep
Title: Enhancing microtubule stabilization rescues cognitive deficits and ameliorates pathological phenotype in an amyloidogenic Alzheimer's disease model.
Volume: 10
Issue: 1
Pages: 14776
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Publication
24252759 | J:277477
 
First Author: Trujillo-Estrada L
Year: 2013
Journal: Acta Neuropathol Commun
Title: In vivo modification of Abeta plaque toxicity as a novel neuroprotective lithium-mediated therapy for Alzheimer's disease pathology.
Volume: 1
Pages: 73
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Publication
22020633 | J:277479
First Author: Sanchez-Varo R
Year: 2012
Journal: Acta Neuropathol
Title: Abnormal accumulation of autophagic vesicles correlates with axonal and synaptic pathology in young Alzheimer's mice hippocampus.
Volume: 123
Issue: 1
Pages: 53-70
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Publication
29134678 | J:257275
First Author: Latta-Mahieu M
Year: 2018
Journal: Glia
Title: Systemic immune-checkpoint blockade with anti-PD1 antibodies does not alter cerebral amyloid-β burden in several amyloid transgenic mouse models.
Volume: 66
Issue: 3
Pages: 492-504
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Publication
29178139 | J:255827
First Author: Gomez-Arboledas A
Year: 2018
Journal: Glia
Title: Phagocytic clearance of presynaptic dystrophies by reactive astrocytes in Alzheimer's disease.
Volume: 66
Issue: 3
Pages: 637-653
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Publication
22079157 | J:188181
First Author: Poisnel G
Year: 2012
Journal: Neurobiol Aging
Title: Increased regional cerebral glucose uptake in an APP/PS1 model of Alzheimer's disease.
Volume: 33
Issue: 9
Pages: 1995-2005
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Publication
23173743 | J:285096
 
First Author: Torres M
Year: 2012
Journal: Mol Neurodegener
Title: Defective lysosomal proteolysis and axonal transport are early pathogenic events that worsen with age leading to increased APP metabolism and synaptic Abeta in transgenic APP/PS1 hippocampus.
Volume: 7
Pages: 59
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Publication
15972962 | J:99507
First Author: Rutten BP
Year: 2005
Journal: Am J Pathol
Title: Age-related loss of synaptophysin immunoreactive presynaptic boutons within the hippocampus of APP751SL, PS1M146L, and APP751SL/PS1M146L transgenic mice.
Volume: 167
Issue: 1
Pages: 161-73
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Publication
11278803 | J:100968
First Author: Schneider I
Year: 2001
Journal: J Biol Chem
Title: Mutant presenilins disturb neuronal calcium homeostasis in the brain of transgenic mice, decreasing the threshold for excitotoxicity and facilitating long-term potentiation.
Volume: 276
Issue: 15
Pages: 11539-44
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Publication
25620700 | J:222897
First Author: Matarin M
Year: 2015
Journal: Cell Rep
Title: A genome-wide gene-expression analysis and database in transgenic mice during development of amyloid or tau pathology.
Volume: 10
Issue: 4
Pages: 633-44
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Publication
33494218 | J:332736
 
First Author: Rossi A
Year: 2021
Journal: Cells
Title: Calcium Signaling and Mitochondrial Function in Presenilin 2 Knock-Out Mice: Looking for Any Loss-of-Function Phenotype Related to Alzheimer's Disease.
Volume: 10
Issue: 2
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Publication
38920631 | J:360321
 
First Author: Rombaut B
Year: 2024
Journal: Cells
Title: Early Inhibition of Phosphodiesterase 4B (PDE4B) Instills Cognitive Resilience in APPswe/PS1dE9 Mice.
Volume: 13
Issue: 12
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Publication
25933409 | J:227541
First Author: Jackson HM
Year: 2015
Journal: PLoS One
Title: DBA/2J genetic background exacerbates spontaneous lethal seizures but lessens amyloid deposition in a mouse model of Alzheimer's disease.
Volume: 10
Issue: 5
Pages: e0125897
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Publication
22221883 | J:188312
First Author: Fuso A
Year: 2012
Journal: Neurobiol Aging
Title: S-adenosylmethionine reduces the progress of the Alzheimer-like features induced by B-vitamin deficiency in mice.
Volume: 33
Issue: 7
Pages: 1482.e1-16
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Publication
27498054 | J:239461
 
First Author: Sarroca S
Year: 2016
Journal: Neurobiol Aging
Title: Preservation of cell-survival mechanisms by the presenilin-1 K239N mutation may cause its milder clinical phenotype.
Volume: 46
Pages: 169-79
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Publication
36875692 | J:333985
 
First Author: Gao Y
Year: 2023
Journal: Front Aging Neurosci
Title: Presenilin 1 deficiency impairs Aβ42-to-Aβ40- and angiotensin-converting activities of ACE.
Volume: 15
Pages: 1098034
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Publication
16753269 | J:111748
First Author: Melnikova T
Year: 2006
Journal: Neuroscience
Title: Cycloxygenase-2 activity promotes cognitive deficits but not increased amyloid burden in a model of Alzheimer's disease in a sex-dimorphic pattern.
Volume: 141
Issue: 3
Pages: 1149-62
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33911285 | J:326194
First Author: Da Mesquita S
Year: 2021
Journal: Nature
Title: Meningeal lymphatics affect microglia responses and anti-Aβ immunotherapy.
Volume: 593
Issue: 7858
Pages: 255-260
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12218652 | J:285259
First Author: Xu G
Year: 2002
Journal: Alzheimer Dis Assoc Disord
Title: Abeta deposition does not cause the aggregation of endogenous tau in transgenic mice.
Volume: 16
Issue: 3
Pages: 196-201
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Publication
28426964 | J:256027
First Author: Abud EM
Year: 2017
Journal: Neuron
Title: iPSC-Derived Human Microglia-like Cells to Study Neurological Diseases.
Volume: 94
Issue: 2
Pages: 278-293.e9
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Publication
32999463 | J:297311
First Author: Badimon A
Year: 2020
Journal: Nature
Title: Negative feedback control of neuronal activity by microglia.
Volume: 586
Issue: 7829
Pages: 417-423
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Publication
35236834 | J:342927
First Author: Zhao Y
Year: 2022
Journal: Nat Commun
Title: ATAD3A oligomerization promotes neuropathology and cognitive deficits in Alzheimer's disease models.
Volume: 13
Issue: 1
Pages: 1121
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Publication
32457076 | J:291055
First Author: Zhang H
Year: 2020
Journal: J Neurosci
Title: A Role of Low-Density Lipoprotein Receptor-Related Protein 4 (LRP4) in Astrocytic Aβ Clearance.
Volume: 40
Issue: 28
Pages: 5347-5361
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Publication
31375314 | J:283800
First Author: Hasselmann J
Year: 2019
Journal: Neuron
Title: Development of a Chimeric Model to Study and Manipulate Human Microglia In Vivo.
Volume: 103
Issue: 6
Pages: 1016-1033.e10
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Publication
33833046 | J:306099
 
First Author: Gulbranson DR
Year: 2021
Journal: eNeuro
Title: Phenotypic Differences between the Alzheimer's Disease-Related hAPP-J20 Model and Heterozygous Zbtb20 Knock-Out Mice.
Volume: 8
Issue: 3
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Publication
23605442 | J:200729
First Author: Crowe SE
Year: 2013
Journal: J Comp Neurol
Title: In vivo characterization of a bigenic fluorescent mouse model of Alzheimer's disease with neurodegeneration.
Volume: 521
Issue: 10
Pages: Spc1
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Publication
33097708 | J:296852
First Author: McQuade A
Year: 2020
Journal: Nat Commun
Title: Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer's disease.
Volume: 11
Issue: 1
Pages: 5370
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Publication
19057621 | J:158080
First Author: Rodríguez JJ
Year: 2009
Journal: Cell Death Differ
Title: Astroglia in dementia and Alzheimer's disease.
Volume: 16
Issue: 3
Pages: 378-85
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Publication
31929156 | J:359194
First Author: Chintapaludi SR
Year: 2020
Journal: J Alzheimers Dis
Title: Staging Alzheimer's Disease in the Brain and Retina of B6.APP/PS1 Mice by Transcriptional Profiling.
Volume: 73
Issue: 4
Pages: 1421-1434
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Publication
23794434 | J:350548
First Author: Podlesniy P
Year: 2013
Journal: Ann Neurol
Title: Low cerebrospinal fluid concentration of mitochondrial DNA in preclinical Alzheimer disease.
Volume: 74
Issue: 5
Pages: 655-68
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Publication
21538175 | J:173252
First Author: Mody N
Year: 2011
Journal: Diabetologia
Title: Susceptibility to diet-induced obesity and glucose intolerance in the APP (SWE)/PSEN1 (A246E) mouse model of Alzheimer's disease is associated with increased brain levels of protein tyrosine phosphatase 1B (PTP1B) and retinol-binding protein 4 (RBP4), and basal phosphorylation of S6 ribosomal protein.
Volume: 54
Issue: 8
Pages: 2143-51
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28636676 | J:247444
First Author: Newman M
Year: 2017
Journal: PLoS One
Title: Mitochondrion to endoplasmic reticulum apposition length in zebrafish embryo spinal progenitors is unchanged in response to perturbations associated with Alzheimer's disease.
Volume: 12
Issue: 6
Pages: e0179859
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Publication
9117892 | J:80782
First Author: Borchelt DR
Year: 1996
Journal: Genet Anal
Title: A vector for expressing foreign genes in the brains and hearts of transgenic mice.
Volume: 13
Issue: 6
Pages: 159-63
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27708157 | J:238628
First Author: Reinders NR
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Amyloid-β effects on synapses and memory require AMPA receptor subunit GluA3.
Volume: 113
Issue: 42
Pages: E6526-E6534
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Publication
14645205 | J:87691
First Author: Jankowsky JL
Year: 2004
Journal: Hum Mol Genet
Title: Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: evidence for augmentation of a 42-specific gamma secretase.
Volume: 13
Issue: 2
Pages: 159-70
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21912965 | J:186741
First Author: Boda E
Year: 2012
Journal: J Mol Neurosci
Title: Brain expression of Kv3 subunits during development, adulthood and aging and in a murine model of Alzheimer's disease.
Volume: 46
Issue: 3
Pages: 606-15
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20529957 | J:163294
First Author: Rothenberg C
Year: 2010
Journal: Hum Mol Genet
Title: Ubiquilin functions in autophagy and is degraded by chaperone-mediated autophagy.
Volume: 19
Issue: 16
Pages: 3219-32
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Publication
28238547 | J:256055
First Author: Espuny-Camacho I
Year: 2017
Journal: Neuron
Title: Hallmarks of Alzheimer's Disease in Stem-Cell-Derived Human Neurons Transplanted into Mouse Brain.
Volume: 93
Issue: 5
Pages: 1066-1081.e8
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Publication
37349313 | J:338494
First Author: Sideris-Lampretsas G
Year: 2023
Journal: Nat Commun
Title: Galectin-3 activates spinal microglia to induce inflammatory nociception in wild type but not in mice modelling Alzheimer's disease.
Volume: 14
Issue: 1
Pages: 3579
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Publication
25852506 | J:242538
 
First Author: Psotta L
Year: 2015
Journal: Front Behav Neurosci
Title: Impact of an additional chronic BDNF reduction on learning performance in an Alzheimer mouse model.
Volume: 9
Pages: 58
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Publication
26112421 | J:329602
 
First Author: Kiyota T
Year: 2015
Journal: Brain Behav Immun
Title: Presenilin-1 familial Alzheimer's disease mutation alters hippocampal neurogenesis and memory function in CCL2 null mice.
Volume: 49
Pages: 311-21
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Publication
22399757 | J:182731
First Author: Watanabe T
Year: 2012
Journal: J Neurosci
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