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Search results 301 to 400 out of 5246 for App

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Type Details Score
Publication
9572310 | J:47155
First Author: Smith MA
Year: 1998
Journal: J Neurochem
Title: Amyloid-beta deposition in Alzheimer transgenic mice is associated with oxidative stress.
Volume: 70
Issue: 5
Pages: 2212-5
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Publication
20176720 | J:160014
First Author: Kohjima M
Year: 2010
Journal: Endocrinology
Title: Increased food intake leads to obesity and insulin resistance in the tg2576 Alzheimer's disease mouse model.
Volume: 151
Issue: 4
Pages: 1532-40
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Publication
31591472 | J:296462
First Author: Scopa C
Year: 2020
Journal: Cell Death Differ
Title: Impaired adult neurogenesis is an early event in Alzheimer's disease neurodegeneration, mediated by intracellular Aβ oligomers.
Volume: 27
Issue: 3
Pages: 934-948
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Publication
11259108 | J:68617
First Author: Quinn J
Year: 2001
Journal: Exp Neurol
Title: Beta-amyloid plaques induce neuritic dystrophy of nitric oxide-producing neurons in a transgenic mouse model of Alzheimer's disease.
Volume: 168
Issue: 2
Pages: 203-12
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Publication
10964604 | J:64354
First Author: Refolo LM
Year: 2000
Journal: Neurobiol Dis
Title: Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model.
Volume: 7
Issue: 4
Pages: 321-31
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Publication
11238054 | J:67895
First Author: Christie R
Year: 2001
Journal: Am J Pathol
Title: Structural and functional disruption of vascular smooth muscle cells in a transgenic mouse model of amyloid angiopathy.
Volume: 158
Issue: 3
Pages: 1065-71
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Publication
15099690 | J:89985
First Author: Wenk GL
Year: 2004
Journal: Neuroscience
Title: The presence of the APP(swe) mutation in mice does not increase the vulnerability of cholinergic basal forebrain neurons to neuroinflammation.
Volume: 125
Issue: 3
Pages: 769-76
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Publication
11425896 | J:70082
First Author: Fitzjohn SM
Year: 2001
Journal: J Neurosci
Title: Age-related impairment of synaptic transmission but normal long-term potentiation in transgenic mice that overexpress the human APP695SWE mutant form of amyloid precursor protein.
Volume: 21
Issue: 13
Pages: 4691-8
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Publication
12093166 | J:77466
First Author: Bednar I
Year: 2002
Journal: Mol Cell Neurosci
Title: Selective nicotinic receptor consequences in APP(SWE) transgenic mice.
Volume: 20
Issue: 2
Pages: 354-65
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Publication
11245811 | J:68010
First Author: Apelt J
Year: 2001
Journal: Brain Res
Title: Beta-amyloid-induced glial expression of both pro- and anti-inflammatory cytokines in cerebral cortex of aged transgenic Tg2576 mice with Alzheimer plaque pathology.
Volume: 894
Issue: 1
Pages: 21-30
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Publication
11430801 | J:70190
First Author: Cherny RA
Year: 2001
Journal: Neuron
Title: Treatment with a copper-zinc chelator markedly and rapidly inhibits beta-amyloid accumulation in Alzheimer's disease transgenic mice.
Volume: 30
Issue: 3
Pages: 665-76
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Publication
21532579 | J:173925
First Author: Bero AW
Year: 2011
Journal: Nat Neurosci
Title: Neuronal activity regulates the regional vulnerability to amyloid-β deposition.
Volume: 14
Issue: 6
Pages: 750-6
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Publication
12402041 | J:80429
First Author: Tan J
Year: 2002
Journal: Nat Neurosci
Title: Role of CD40 ligand in amyloidosis in transgenic Alzheimer's mice.
Volume: 5
Issue: 12
Pages: 1288-93
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Publication
22753410 | J:190247
First Author: Walls KC
Year: 2012
Journal: J Biol Chem
Title: Swedish Alzheimer mutation induces mitochondrial dysfunction mediated by HSP60 mislocalization of amyloid precursor protein (APP) and beta-amyloid.
Volume: 287
Issue: 36
Pages: 30317-27
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Publication
34272583 | J:350898
First Author: Roos TT
Year: 2021
Journal: Acta Neuropathol
Title: Neuronal spreading and plaque induction of intracellular Aβ and its disruption of Aβ homeostasis.
Volume: 142
Issue: 4
Pages: 669-687
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34805789 | J:315466
First Author: Zhang J
Year: 2021
Journal: iScience
Title: Identification of early-onset photoreceptor degeneration in transgenic mouse models of Alzheimer's disease.
Volume: 24
Issue: 11
Pages: 103327
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35045289 | J:324407
First Author: Zarhin D
Year: 2022
Journal: Cell Rep
Title: Disrupted neural correlates of anesthesia and sleep reveal early circuit dysfunctions in Alzheimer models.
Volume: 38
Issue: 3
Pages: 110268
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7845465 | J:23080
First Author: Games D
Year: 1995
Journal: Nature
Title: Alzheimer-type neuropathology in transgenic mice overexpressing V717F beta-amyloid precursor protein.
Volume: 373
Issue: 6514
Pages: 523-7
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9371838 | J:44603
First Author: Sturchler-Pierrat C
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology.
Volume: 94
Issue: 24
Pages: 13287-92
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Publication
18063223 | J:152965
First Author: Li L
Year: 2009
Journal: Neurobiol Aging
Title: Hypoxia increases Abeta generation by altering beta- and gamma-cleavage of APP.
Volume: 30
Issue: 7
Pages: 1091-8
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Publication
19619138 | J:152489
First Author: Choi JH
Year: 2009
Journal: J Neurochem
Title: Age-dependent dysregulation of brain amyloid precursor protein in the Ts65Dn Down syndrome mouse model.
Volume: 110
Issue: 6
Pages: 1818-27
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Publication
11476589 | J:71061
First Author: Jaffar S
Year: 2001
Journal: Exp Neurol
Title: Neuropathology of mice carrying mutant APP(swe) and/or PS1(M146L) transgenes: alterations in the p75(NTR) cholinergic basal forebrain septohippocampal pathway.
Volume: 170
Issue: 2
Pages: 227-43
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9427614 | J:45724
First Author: Holcomb L
Year: 1998
Journal: Nat Med
Title: Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes.
Volume: 4
Issue: 1
Pages: 97-100
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Publication
13678669 | J:109503
First Author: Luo Y
Year: 2003
Journal: Neurobiol Dis
Title: BACE1 (beta-secretase) knockout mice do not acquire compensatory gene expression changes or develop neural lesions over time.
Volume: 14
Issue: 1
Pages: 81-8
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Publication
22895721 | J:187719
First Author: Chen Y
Year: 2012
Journal: J Neurosci
Title: Alzheimer's β-secretase (BACE1) regulates the cAMP/PKA/CREB pathway independently of β-amyloid.
Volume: 32
Issue: 33
Pages: 11390-5
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36750595 | J:334802
First Author: Ulku I
Year: 2023
Journal: Sci Rep
Title: Mechanisms of amyloid-β34 generation indicate a pivotal role for BACE1 in amyloid homeostasis.
Volume: 13
Issue: 1
Pages: 2216
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7576662 | J:29880
First Author: Hsiao KK
Year: 1995
Journal: Neuron
Title: Age-related CNS disorder and early death in transgenic FVB/N mice overexpressing Alzheimer amyloid precursor proteins.
Volume: 15
Issue: 5
Pages: 1203-18
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Publication
30283027 | J:278568
First Author: Tanaka H
Year: 2018
Journal: Mol Psychiatry
Title: The intellectual disability gene PQBP1 rescues Alzheimer's disease pathology.
Volume: 23
Issue: 10
Pages: 2090-2110
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Publication
21041302 | J:167361
First Author: Cheng S
Year: 2010
Journal: J Biol Chem
Title: GRK5 deficiency accelerates {beta}-amyloid accumulation in Tg2576 mice via impaired cholinergic activity.
Volume: 285
Issue: 53
Pages: 41541-8
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Publication
19515914 | J:149815
First Author: Hoe HS
Year: 2009
Journal: J Neurosci
Title: Interaction of reelin with amyloid precursor protein promotes neurite outgrowth.
Volume: 29
Issue: 23
Pages: 7459-73
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18691390 | J:140325
First Author: Shimazawa M
Year: 2008
Journal: J Neurochem
Title: Reduced retinal function in amyloid precursor protein-over-expressing transgenic mice via attenuating glutamate-N-methyl-d-aspartate receptor signaling.
Volume: 107
Issue: 1
Pages: 279-90
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Publication
22393443 | J:185288
First Author: Trushina E
Year: 2012
Journal: PLoS One
Title: Defects in mitochondrial dynamics and metabolomic signatures of evolving energetic stress in mouse models of familial Alzheimer's disease.
Volume: 7
Issue: 2
Pages: e32737
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Publication
19834064 | J:154685
First Author: Doi Y
Year: 2009
Journal: Am J Pathol
Title: Microglia activated with the toll-like receptor 9 ligand CpG attenuate oligomeric amyloid {beta} neurotoxicity in in vitro and in vivo models of Alzheimer's disease.
Volume: 175
Issue: 5
Pages: 2121-32
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Publication
17360920 | J:141659
First Author: Park KH
Year: 2007
Journal: J Neurosci
Title: Conditional neuronal simian virus 40 T antigen expression induces Alzheimer-like tau and amyloid pathology in mice.
Volume: 27
Issue: 11
Pages: 2969-78
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19818105 | J:157037
First Author: Patel NS
Year: 2010
Journal: J Neurochem
Title: Alzheimer's beta-amyloid peptide blocks vascular endothelial growth factor mediated signaling via direct interaction with VEGFR-2.
Volume: 112
Issue: 1
Pages: 66-76
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29950521 | J:270135
First Author: Kara E
Year: 2018
Journal: J Biol Chem
Title: A flow cytometry-based in vitro assay reveals that formation of apolipoprotein E (ApoE)-amyloid beta complexes depends on ApoE isoform and cell type.
Volume: 293
Issue: 34
Pages: 13247-13256
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Publication
19135431 | J:148219
 
First Author: Catlow BJ
Year: 2009
Journal: Brain Res
Title: Effects of environmental enrichment and physical activity on neurogenesis in transgenic PS1/APP mice.
Volume: 1256
Pages: 173-9
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17573346 | J:124796
First Author: Czirr E
Year: 2007
Journal: J Biol Chem
Title: Insensitivity to Abeta42-lowering nonsteroidal anti-inflammatory drugs and gamma-secretase inhibitors is common among aggressive presenilin-1 mutations.
Volume: 282
Issue: 34
Pages: 24504-13
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22608241 | J:191360
First Author: Morales-Corraliza J
Year: 2013
Journal: Neurobiol Aging
Title: Immunization targeting a minor plaque constituent clears β-amyloid and rescues behavioral deficits in an Alzheimer's disease mouse model.
Volume: 34
Issue: 1
Pages: 137-45
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10448051 | J:57518
First Author: McGowan E
Year: 1999
Journal: Neurobiol Dis
Title: Amyloid phenotype characterization of transgenic mice overexpressing both mutant amyloid precursor protein and mutant presenilin 1 transgenes.
Volume: 6
Issue: 4
Pages: 231-44
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9354339 | J:43788
First Author: Borchelt DR
Year: 1997
Journal: Neuron
Title: Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins.
Volume: 19
Issue: 4
Pages: 939-45
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33340762 | J:305597
 
First Author: Shahnur A
Year: 2021
Journal: Biochem Biophys Res Commun
Title: A potential defense mechanism against amyloid deposition in cerebellum.
Volume: 535
Pages: 25-32
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10037741 | J:53800
First Author: Moechars D
Year: 1999
Journal: J Biol Chem
Title: Early phenotypic changes in transgenic mice that overexpress different mutants of amyloid precursor protein in brain.
Volume: 274
Issue: 10
Pages: 6483-92
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16298242 | J:105265
First Author: Lord A
Year: 2006
Journal: Neurobiol Aging
Title: The Arctic Alzheimer mutation facilitates early intraneuronal Abeta aggregation and senile plaque formation in transgenic mice.
Volume: 27
Issue: 1
Pages: 67-77
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21224067 | J:168082
First Author: Hafez D
Year: 2011
Journal: Am J Pathol
Title: Neprilysin-2 is an important β-amyloid degrading enzyme.
Volume: 178
Issue: 1
Pages: 306-12
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27889678 | J:239743
 
First Author: Fontana R
Year: 2017
Journal: Neurobiol Aging
Title: Early hippocampal hyperexcitability in PS2APP mice: role of mutant PS2 and APP.
Volume: 50
Pages: 64-76
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27064279 | J:234942
First Author: Xu W
Year: 2016
Journal: J Clin Invest
Title: Amyloid precursor protein-mediated endocytic pathway disruption induces axonal dysfunction and neurodegeneration.
Volume: 126
Issue: 5
Pages: 1815-33
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9302276 | J:43446
First Author: Carlson GA
Year: 1997
Journal: Hum Mol Genet
Title: Genetic modification of the phenotypes produced by amyloid precursor protein overexpression in transgenic mice.
Volume: 6
Issue: 11
Pages: 1951-9
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23599427 | J:199613
First Author: Poon WW
Year: 2013
Journal: J Biol Chem
Title: β-Amyloid (Aβ) oligomers impair brain-derived neurotrophic factor retrograde trafficking by down-regulating ubiquitin C-terminal hydrolase, UCH-L1.
Volume: 288
Issue: 23
Pages: 16937-48
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Publication
19074441 | J:147910
First Author: AbdAlla S
Year: 2009
Journal: J Biol Chem
Title: Angiotensin II AT2 receptor oligomers mediate G-protein dysfunction in an animal model of Alzheimer disease.
Volume: 284
Issue: 10
Pages: 6554-65
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1756177 | J:2308
First Author: De Strooper B
Year: 1991
Journal: Biochim Biophys Acta
Title: The amyloid beta protein precursor or proteinase nexin II from mouse is closer related to its human homolog than previously reported.
Volume: 1129
Issue: 1
Pages: 141-3
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33314529 | J:331908
First Author: Audrain M
Year: 2021
Journal: Alzheimers Dement
Title: Reactive or transgenic increase in microglial TYROBP reveals a TREM2-independent TYROBP-APOE link in wild-type and Alzheimer's-related mice.
Volume: 17
Issue: 2
Pages: 149-163
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16207708 | J:105901
First Author: Wahrle SE
Year: 2005
Journal: J Biol Chem
Title: Deletion of Abca1 increases Abeta deposition in the PDAPP transgenic mouse model of Alzheimer disease.
Volume: 280
Issue: 52
Pages: 43236-42
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21266574 | J:170948
First Author: Barbagallo AP
Year: 2011
Journal: J Biol Chem
Title: A single tyrosine residue in the amyloid precursor protein intracellular domain is essential for developmental function.
Volume: 286
Issue: 11
Pages: 8717-21
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11102478 | J:66147
First Author: Siman R
Year: 2000
Journal: J Neurosci
Title: Presenilin-1 P264L knock-in mutation: differential effects on abeta production, amyloid deposition, and neuronal vulnerability.
Volume: 20
Issue: 23
Pages: 8717-26
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15927307 | J:105460
First Author: Wu ZL
Year: 2006
Journal: Neurobiol Aging
Title: Comparative analysis of cortical gene expression in mouse models of Alzheimer's disease.
Volume: 27
Issue: 3
Pages: 377-86
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10964951 | J:64209
First Author: Dewachter I
Year: 2000
Journal: J Neurosci
Title: Aging increased amyloid peptide and caused amyloid plaques in brain of old APP/V717I transgenic mice by a different mechanism than mutant presenilin1.
Volume: 20
Issue: 17
Pages: 6452-8
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Publication
21655287 | J:220937
First Author: Lull ME
Year: 2011
Journal: PLoS One
Title: Chronic apocynin treatment attenuates beta amyloid plaque size and microglial number in hAPP(751)(SL) mice.
Volume: 6
Issue: 5
Pages: e20153
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Publication
27097852 | J:324345
 
First Author: Srinivasan K
Year: 2016
Journal: Nat Commun
Title: Untangling the brain's neuroinflammatory and neurodegenerative transcriptional responses.
Volume: 7
Pages: 11295
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24094580 | J:212604
First Author: Deng Y
Year: 2014
Journal: Neurobiol Aging
Title: β-amyloid impairs the regulation of N-methyl-D-aspartate receptors by glycogen synthase kinase 3.
Volume: 35
Issue: 3
Pages: 449-59
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16025111 | J:101438
First Author: Snyder EM
Year: 2005
Journal: Nat Neurosci
Title: Regulation of NMDA receptor trafficking by amyloid-beta.
Volume: 8
Issue: 8
Pages: 1051-8
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19551139 | J:150191
First Author: Turdi S
Year: 2009
Journal: PLoS One
Title: Cardiomyocyte contractile dysfunction in the APPswe/PS1dE9 mouse model of Alzheimer's disease.
Volume: 4
Issue: 6
Pages: e6033
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Publication
38587131 | J:350558
First Author: Späte E
Year: 2024
Journal: Glia
Title: Downregulated expression of lactate dehydrogenase in adult oligodendrocytes and its implication for the transfer of glycolysis products to axons.
Volume: 72
Issue: 8
Pages: 1374-1391
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29548672 | J:272420
First Author: Datta M
Year: 2018
Journal: Immunity
Title: Histone Deacetylases 1 and 2 Regulate Microglia Function during Development, Homeostasis, and Neurodegeneration in a Context-Dependent Manner.
Volume: 48
Issue: 3
Pages: 514-529.e6
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Publication
22144675 | J:181521
First Author: Guo Q
Year: 2012
Journal: J Biol Chem
Title: Amyloid precursor protein revisited: neuron-specific expression and highly stable nature of soluble derivatives.
Volume: 287
Issue: 4
Pages: 2437-45
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16723713 | J:109124
First Author: Kitazawa M
Year: 2006
Journal: Am J Pathol
Title: Genetically augmenting Abeta42 levels in skeletal muscle exacerbates inclusion body myositis-like pathology and motor deficits in transgenic mice.
Volume: 168
Issue: 6
Pages: 1986-97
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20049331 | J:336391
First Author: Abisambra JF
Year: 2010
Journal: PLoS One
Title: LDLR expression and localization are altered in mouse and human cell culture models of Alzheimer's disease.
Volume: 5
Issue: 1
Pages: e8556
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31004319 | J:289228
First Author: Van Gool B
Year: 2019
Journal: Mol Neurobiol
Title: LRP1 Has a Predominant Role in Production over Clearance of Aβ in a Mouse Model of Alzheimer's Disease.
Volume: 56
Issue: 10
Pages: 7234-7245
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22336193 | J:191170
First Author: Guo Q
Year: 2012
Journal: Neurobiol Aging
Title: Central CRF system perturbation in an Alzheimer's disease knockin mouse model.
Volume: 33
Issue: 11
Pages: 2678-91
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Publication
28899917 | J:253021
First Author: William CM
Year: 2017
Journal: J Neurosci
Title: Activity-Dependent Dysfunction in Visual and Olfactory Sensory Systems in Mouse Models of Down Syndrome.
Volume: 37
Issue: 41
Pages: 9880-9888
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Publication
25437557 | J:271362
First Author: Wang X
Year: 2014
Journal: Cell Rep
Title: Sorting nexin 27 regulates Aβ production through modulating γ-secretase activity.
Volume: 9
Issue: 3
Pages: 1023-33
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Publication
33893290 | J:304519
First Author: Baglietto-Vargas D
Year: 2021
Journal: Nat Commun
Title: Generation of a humanized Aβ expressing mouse demonstrating aspects of Alzheimer's disease-like pathology.
Volume: 12
Issue: 1
Pages: 2421
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Publication
20693289 | J:166379
First Author: Li H
Year: 2010
Journal: J Biol Chem
Title: Genetic dissection of the amyloid precursor protein in developmental function and amyloid pathogenesis.
Volume: 285
Issue: 40
Pages: 30598-605
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12431992 | J:81726
First Author: Herms J
Year: 2003
Journal: J Biol Chem
Title: Capacitive calcium entry is directly attenuated by mutant presenilin-1, independent of the expression of the amyloid precursor protein.
Volume: 278
Issue: 4
Pages: 2484-9
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Publication
27425247 | J:238664
First Author: Park SA
Year: 2016
Journal: Biochem Biophys Res Commun
Title: Deficiency in either COX-1 or COX-2 genes does not affect amyloid beta protein burden in amyloid precursor protein transgenic mice.
Volume: 478
Issue: 1
Pages: 286-292
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Publication
24278307 | J:209782
First Author: Guo Q
Year: 2013
Journal: PLoS One
Title: Modeling Alzheimer's disease in mouse without mutant protein overexpression: cooperative and independent effects of Aβ and tau.
Volume: 8
Issue: 11
Pages: e80706
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11466532 | J:71163
First Author: Ott MO
Year: 2001
Journal: Dev Genes Evol
Title: A gene trap insertion reveals that amyloid precursor protein expression is a very early event in murine embryogenesis.
Volume: 211
Issue: 7
Pages: 355-7
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12414533 | J:79908
First Author: Takahashi RH
Year: 2002
Journal: Am J Pathol
Title: Intraneuronal Alzheimer abeta42 accumulates in multivesicular bodies and is associated with synaptic pathology.
Volume: 161
Issue: 5
Pages: 1869-79
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Publication
12064470 | J:76046
First Author: DeMattos RB
Year: 2002
Journal: J Neurochem
Title: Plaque-associated disruption of CSF and plasma amyloid-beta (Abeta) equilibrium in a mouse model of Alzheimer's disease.
Volume: 81
Issue: 2
Pages: 229-36
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10413774 | J:56520
First Author: Nakagawa Y
Year: 1999
Journal: J Comp Neurol
Title: Traumatic brain injury in young, amyloid-beta peptide overexpressing transgenic mice induces marked ipsilateral hippocampal atrophy and diminished Abeta deposition during aging.
Volume: 411
Issue: 3
Pages: 390-8
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Publication
11140684 | J:66409
First Author: Chen G
Year: 2000
Journal: Nature
Title: A learning deficit related to age and beta-amyloid plaques in a mouse model of Alzheimer's disease.
Volume: 408
Issue: 6815
Pages: 975-9
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Publication
10980129 | J:64393
First Author: Murphy GM Jr
Year: 2000
Journal: Am J Pathol
Title: Expression of macrophage colony-stimulating factor receptor is increased in the AbetaPP(V717F) transgenic mouse model of Alzheimer's disease.
Volume: 157
Issue: 3
Pages: 895-904
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Publication
22085641 | J:182808
First Author: Bailey AR
Year: 2012
Journal: FASEB J
Title: Aberrant T-lymphocyte development and function in mice overexpressing human soluble amyloid precursor protein-α: implications for autism.
Volume: 26
Issue: 3
Pages: 1040-51
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Publication
16289866 | J:107982
First Author: Lee KW
Year: 2006
Journal: Neurobiol Dis
Title: Progressive neuronal loss and behavioral impairments of transgenic C57BL/6 inbred mice expressing the carboxy terminus of amyloid precursor protein.
Volume: 22
Issue: 1
Pages: 10-24
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Publication
10783292 | J:61838
First Author: Dodart JC
Year: 2000
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