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Search results 301 to 400 out of 419 for Bace1

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Category: Publication
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Type Details Score
Publication
6375662 | -
First Author: Glenner GG
Year: 1984
Journal: Biochem Biophys Res Commun
Title: Alzheimer's disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein.
Volume: 120
Issue: 3
Pages: 885-90
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Publication
10656250 | -
First Author: Hussain I
Year: 1999
Journal: Mol Cell Neurosci
Title: Identification of a novel aspartic protease (Asp 2) as beta-secretase.
Volume: 14
Issue: 6
Pages: 419-27
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Publication
12391600 | -
First Author: Citron M
Year: 2002
Journal: J Neurosci Res
Title: Beta-secretase as a target for the treatment of Alzheimer's disease.
Volume: 70
Issue: 3
Pages: 373-9
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Publication
11585763 | -
First Author: Chakraborty M
Year: 2001
Journal: Cancer Res
Title: Par-4 drives trafficking and activation of Fas and Fasl to induce prostate cancer cell apoptosis and tumor regression.
Volume: 61
Issue: 19
Pages: 7255-63
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Publication
8943350 | -
First Author: Johnstone RW
Year: 1996
Journal: Mol Cell Biol
Title: A novel repressor, par-4, modulates transcription and growth suppression functions of the Wilms' tumor suppressor WT1.
Volume: 16
Issue: 12
Pages: 6945-56
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Publication
15671026 | -
First Author: Xie J
Year: 2005
Journal: J Biol Chem
Title: PAR-4 is involved in regulation of beta-secretase cleavage of the Alzheimer amyloid precursor protein.
Volume: 280
Issue: 14
Pages: 13824-32
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Publication
11948243 | J:75039
First Author: Bodendorf U
Year: 2002
Journal: J Neurochem
Title: Expression of human beta-secretase in the mouse brain increases the steady-state level of beta-amyloid.
Volume: 80
Issue: 5
Pages: 799-806
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Publication
30858603 | J:277515
First Author: Park H
Year: 2019
Journal: Nat Neurosci
Title: In vivo neuronal gene editing via CRISPR-Cas9 amphiphilic nanocomplexes alleviates deficits in mouse models of Alzheimer's disease.
Volume: 22
Issue: 4
Pages: 524-528
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Publication
19416837 | J:148402
First Author: Bengoechea TG
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: p75 reduces beta-amyloid-induced sympathetic innervation deficits in an Alzheimer's disease mouse model.
Volume: 106
Issue: 19
Pages: 7870-5
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Publication
17724122 | J:134832
First Author: He P
Year: 2007
Journal: J Cell Biol
Title: Deletion of tumor necrosis factor death receptor inhibits amyloid beta generation and prevents learning and memory deficits in Alzheimer's mice.
Volume: 178
Issue: 5
Pages: 829-41
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Publication
18687504 | J:161837
First Author: Jo DG
Year: 2010
Journal: Neurobiol Aging
Title: Evidence that gamma-secretase mediates oxidative stress-induced beta-secretase expression in Alzheimer's disease.
Volume: 31
Issue: 6
Pages: 917-25
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Publication
22105352 | J:178937
First Author: Wen L
Year: 2011
Journal: J Cell Biol
Title: VPS35 haploinsufficiency increases Alzheimer's disease neuropathology.
Volume: 195
Issue: 5
Pages: 765-79
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Publication
27447728 | J:249227
First Author: Whitehouse IJ
Year: 2016
Journal: PLoS One
Title: Ablation of Prion Protein in Wild Type Human Amyloid Precursor Protein (APP) Transgenic Mice Does Not Alter The Proteolysis of APP, Levels of Amyloid-β or Pathologic Phenotype.
Volume: 11
Issue: 7
Pages: e0159119
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Publication
23133641 | J:195596
First Author: Yang SG
Year: 2012
Journal: PLoS One
Title: A peptide binding to the β-site of APP improves spatial memory and attenuates Aβ burden in Alzheimer's disease transgenic mice.
Volume: 7
Issue: 11
Pages: e48540
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Publication
32029735 | J:304213
First Author: Durrant CS
Year: 2020
Journal: Cell Death Dis
Title: Beta secretase 1-dependent amyloid precursor protein processing promotes excessive vascular sprouting through NOTCH3 signalling.
Volume: 11
Issue: 2
Pages: 98
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Publication
19548013 | J:152747
First Author: Tong Y
Year: 2010
Journal: Neurogenetics
Title: COL25A1 triggers and promotes Alzheimer's disease-like pathology in vivo.
Volume: 11
Issue: 1
Pages: 41-52
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Publication
35579602 | J:332590
 
First Author: Ahmad T
Year: 2022
Journal: J Cell Biol
Title: Transcytosis and trans-synaptic retention by postsynaptic ErbB4 underlie axonal accumulation of NRG3.
Volume: 221
Issue: 7
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18936252 | J:140648
First Author: Sakurai T
Year: 2008
Journal: J Cell Biol
Title: Membrane microdomain switching: a regulatory mechanism of amyloid precursor protein processing.
Volume: 183
Issue: 2
Pages: 339-52
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Publication
25590804 | J:315368
 
First Author: Mouton-Liger F
Year: 2015
Journal: Cell Death Dis
Title: PKR downregulation prevents neurodegeneration and β-amyloid production in a thiamine-deficient model.
Volume: 6
Pages: e1594
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Publication
21199326 | J:205664
First Author: Mishra M
Year: 2011
Journal: J Cell Mol Med
Title: P60TRP interferes with the GPCR/secretase pathway to mediate neuronal survival and synaptogenesis.
Volume: 15
Issue: 11
Pages: 2462-77
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Publication
34029592 | J:306268
   
First Author: Gaborit B
Year: 2021
Journal: J Biol Chem
Title: The aminosterol Claramine inhibits β-secretase 1-mediated insulin receptor cleavage.
Pages: 100818
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Publication
17255335 | J:117817
First Author: Yamamoto M
Year: 2007
Journal: Am J Pathol
Title: Interferon-gamma and tumor necrosis factor-alpha regulate amyloid-beta plaque deposition and beta-secretase expression in Swedish mutant APP transgenic mice.
Volume: 170
Issue: 2
Pages: 680-92
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Publication
27796320 | J:271412
 
First Author: Ma Z
Year: 2016
Journal: Sci Rep
Title: Orexin signaling regulates both the hippocampal clock and the circadian oscillation of Alzheimer's disease-risk genes.
Volume: 6
Pages: 36035
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Publication
31055081 | J:283443
First Author: Fanaee-Danesh E
Year: 2019
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Astaxanthin exerts protective effects similar to bexarotene in Alzheimer's disease by modulating amyloid-beta and cholesterol homeostasis in blood-brain barrier endothelial cells.
Volume: 1865
Issue: 9
Pages: 2224-2245
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Publication
26778963 | J:310589
 
First Author: Piedrahita D
Year: 2015
Journal: Front Cell Neurosci
Title: β-Secretase 1's Targeting Reduces Hyperphosphorilated Tau, Implying Autophagy Actors in 3xTg-AD Mice.
Volume: 9
Pages: 498
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Publication
36758468 | J:351246
 
First Author: Li YY
Year: 2023
Journal: Neurobiol Aging
Title: Orexin-A aggravates cognitive deficits in 3xTg-AD mice by exacerbating synaptic plasticity impairment and affecting amyloid β metabolism.
Volume: 124
Pages: 71-84
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Publication
37171575 | J:351245
First Author: Ricciardi NR
Year: 2023
Journal: Mol Neurobiol
Title: Investigating the Synergistic Potential of Low-Dose HDAC3 Inhibition and Radiotherapy in Alzheimer's Disease Models.
Volume: 60
Issue: 8
Pages: 4811-4827
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Publication
19183260 | J:146855
First Author: Kitazawa M
Year: 2009
Journal: J Neurochem
Title: Chronic copper exposure exacerbates both amyloid and tau pathology and selectively dysregulates cdk5 in a mouse model of AD.
Volume: 108
Issue: 6
Pages: 1550-60
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Publication
39110781 | J:353793
First Author: Han J
Year: 2024
Journal: Sci Transl Med
Title: Engineered exosomes with a photoinducible protein delivery system enable CRISPR-Cas-based epigenome editing in Alzheimer's disease.
Volume: 16
Issue: 759
Pages: eadi4830
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Publication
36241022 | J:348507
 
First Author: Valle ML
Year: 2022
Journal: Mol Cell Neurosci
Title: Thiamine insufficiency induces Hypoxia Inducible Factor-1α as an upstream mediator for neurotoxicity and AD-like pathology.
Volume: 123
Pages: 103785
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Publication
35244207 | J:349610
First Author: Yu ZY
Year: 2022
Journal: J Neurochem
Title: Inhibiting α1-adrenergic receptor signaling pathway ameliorates AD-type pathologies and behavioral deficits in APPswe/PS1 mouse model.
Volume: 161
Issue: 3
Pages: 293-307
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Publication
30506868 | J:273251
First Author: Truong PH
Year: 2019
Journal: Glia
Title: Amyloid precursor protein and amyloid precursor-like protein 2 have distinct roles in modulating myelination, demyelination, and remyelination of axons.
Volume: 67
Issue: 3
Pages: 525-538
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Publication
34958873 | J:351594
 
First Author: Wang ZH
Year: 2022
Journal: Prog Neurobiol
Title: Neuronal ApoE4 stimulates C/EBPβ activation, promoting Alzheimer's disease pathology in a mouse model.
Volume: 209
Pages: 102212
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Publication
30506549 | J:327646
First Author: De Rossi P
Year: 2019
Journal: Brain Pathol
Title: Aberrant accrual of BIN1 near Alzheimer's disease amyloid deposits in transgenic models.
Volume: 29
Issue: 4
Pages: 485-501
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Publication
33848635 | J:306424
 
First Author: Janssens J
Year: 2021
Journal: Neurobiol Dis
Title: Passive immunotherapy with a novel antibody against 3pE-modified Aβ demonstrates potential for enhanced efficacy and favorable safety in combination with BACE inhibitor treatment in plaque-depositing mice.
Volume: 154
Pages: 105365
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Publication
30692199 | J:275958
First Author: Andrew RJ
Year: 2019
Journal: J Biol Chem
Title: Reduction of the expression of the late-onset Alzheimer's disease (AD) risk-factor BIN1 does not affect amyloid pathology in an AD mouse model.
Volume: 294
Issue: 12
Pages: 4477-4487
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14701757 | J:285020
First Author: Christensen MA
Year: 2004
Journal: Mol Cell Biol
Title: Transcriptional regulation of BACE1, the beta-amyloid precursor protein beta-secretase, by Sp1.
Volume: 24
Issue: 2
Pages: 865-74
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Publication
15452128 | J:95174
First Author: Chiocco MJ
Year: 2004
Journal: J Biol Chem
Title: Altered amyloid-beta metabolism and deposition in genomic-based beta-secretase transgenic mice.
Volume: 279
Issue: 50
Pages: 52535-42
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16387391 | J:117963
First Author: Chiocco MJ
Year: 2007
Journal: Neurobiol Aging
Title: Spatial and temporal control of age-related APP processing in genomic-based beta-secretase transgenic mice.
Volume: 28
Issue: 1
Pages: 75-84
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Publication
20384814 | J:159858
First Author: Zhang XM
Year: 2010
Journal: Eur J Neurosci
Title: Functional deprivation promotes amyloid plaque pathogenesis in Tg2576 mouse olfactory bulb and piriform cortex.
Volume: 31
Issue: 4
Pages: 710-21
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Publication
32455709 | J:304191
 
First Author: Park SY
Year: 2020
Journal: Cells
Title: SPON1 Can Reduce Amyloid Beta and Reverse Cognitive Impairment and Memory Dysfunction in Alzheimer's Disease Mouse Model.
Volume: 9
Issue: 5
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23595759 | J:196964
First Author: Corbett BF
Year: 2013
Journal: J Neurosci
Title: Sodium channel cleavage is associated with aberrant neuronal activity and cognitive deficits in a mouse model of Alzheimer's disease.
Volume: 33
Issue: 16
Pages: 7020-6
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15465277 | J:100042
First Author: Apelt J
Year: 2004
Journal: Int J Dev Neurosci
Title: Aging-related increase in oxidative stress correlates with developmental pattern of beta-secretase activity and beta-amyloid plaque formation in transgenic Tg2576 mice with Alzheimer-like pathology.
Volume: 22
Issue: 7
Pages: 475-84
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15788759 | J:128887
First Author: Lim GP
Year: 2005
Journal: J Neurosci
Title: A diet enriched with the omega-3 fatty acid docosahexaenoic acid reduces amyloid burden in an aged Alzheimer mouse model.
Volume: 25
Issue: 12
Pages: 3032-40
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Publication
23474306 | J:202423
First Author: Gerenu G
Year: 2013
Journal: Biochim Biophys Acta
Title: Early cognitive stimulation compensates for memory and pathological changes in Tg2576 mice.
Volume: 1832
Issue: 6
Pages: 837-47
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21435457 | J:169845
First Author: Chu J
Year: 2011
Journal: Am J Pathol
Title: Pharmacologic blockade of 5-lipoxygenase improves the amyloidotic phenotype of an Alzheimer's disease transgenic mouse model involvement of γ-secretase.
Volume: 178
Issue: 4
Pages: 1762-9
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22542680 | J:192436
 
First Author: Cai Y
Year: 2012
Journal: Neuroscience
Title: An age-related axon terminal pathology around the first olfactory relay that involves amyloidogenic protein overexpression without plaque formation.
Volume: 215
Pages: 160-73
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24824215 | J:214328
First Author: Jiang H
Year: 2014
Journal: Hum Mol Genet
Title: Genetic deletion of TNFRII gene enhances the Alzheimer-like pathology in an APP transgenic mouse model via reduction of phosphorylated IκBα.
Volume: 23
Issue: 18
Pages: 4906-18
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Publication
23472157 | J:200200
First Author: He P
Year: 2013
Journal: PLoS One
Title: Chronic administration of anti-stroke herbal medicine TongLuoJiuNao reduces amyloidogenic processing of amyloid precursor protein in a mouse model of Alzheimer's disease.
Volume: 8
Issue: 3
Pages: e58181
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Publication
23405115 | J:197210
First Author: He P
Year: 2013
Journal: PLoS One
Title: Long-term treatment of thalidomide ameliorates amyloid-like pathology through inhibition of β-secretase in a mouse model of Alzheimer's disease.
Volume: 8
Issue: 2
Pages: e55091
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14645205 | J:87691
First Author: Jankowsky JL
Year: 2004
Journal: Hum Mol Genet
Title: Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: evidence for augmentation of a 42-specific gamma secretase.
Volume: 13
Issue: 2
Pages: 159-70
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23223301 | J:193190
First Author: Kummer MP
Year: 2012
Journal: J Neurosci
Title: Mrp14 deficiency ameliorates amyloid β burden by increasing microglial phagocytosis and modulation of amyloid precursor protein processing.
Volume: 32
Issue: 49
Pages: 17824-9
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36688823 | J:338758
First Author: Schnöder L
Year: 2023
Journal: FASEB J
Title: Deficiency of IKKβ in neurons ameliorates Alzheimer's disease pathology in APP- and tau-transgenic mice.
Volume: 37
Issue: 2
Pages: e22778
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Publication
33411695 | J:308987
 
First Author: Bouza AA
Year: 2021
Journal: JCI Insight
Title: Sodium channel β1 subunits participate in regulated intramembrane proteolysis-excitation coupling.
Volume: 6
Issue: 3
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Publication
30803762 | J:291180
First Author: Quartey MO
Year: 2019
Journal: Biochem Biophys Res Commun
Title: Age- and sex-dependent profiles of APP fragments and key secretases align with changes in despair-like behavior and cognition in young APPSwe/Ind mice.
Volume: 511
Issue: 2
Pages: 454-459
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Publication
36396721 | J:357318
First Author: Tyagi A
Year: 2022
Journal: Sci Rep
Title: Sirt3 deficiency induced down regulation of insulin degrading enzyme in comorbid Alzheimer's disease with metabolic syndrome.
Volume: 12
Issue: 1
Pages: 19808
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Publication
30243987 | J:269965
 
First Author: Lu MH
Year: 2019
Journal: Exp Neurol
Title: Inhibition of sphingomyelin synthase 1 ameliorates alzheimer-like pathology in APP/PS1 transgenic mice through promoting lysosomal degradation of BACE1.
Volume: 311
Pages: 67-79
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Publication
25143627 | J:216162
First Author: Bae M
Year: 2014
Journal: J Neurosci
Title: Activation of TRPML1 clears intraneuronal Aβ in preclinical models of HIV infection.
Volume: 34
Issue: 34
Pages: 11485-503
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Publication
22188425 | J:290008
First Author: Aso E
Year: 2012
Journal: Brain Pathol
Title: Amyloid generation and dysfunctional immunoproteasome activation with disease progression in animal model of familial Alzheimer's disease.
Volume: 22
Issue: 5
Pages: 636-53
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21670066 | J:175718
First Author: Zhou X
Year: 2011
Journal: FASEB J
Title: Interaction between amyloid precursor protein and Nogo receptors regulates amyloid deposition.
Volume: 25
Issue: 9
Pages: 3146-56
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31981651 | J:291405
 
First Author: Lian B
Year: 2020
Journal: Behav Brain Res
Title: Hippocampal overexpression of SGK1 ameliorates spatial memory, rescues Aβ pathology and actin cytoskeleton polymerization in middle-aged APP/PS1 mice.
Volume: 383
Pages: 112503
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Publication
28733667 | J:247602
First Author: Shi Q
Year: 2017
Journal: Sci Rep
Title: RTN1 and RTN3 protein are differentially associated with senile plaques in Alzheimer's brains.
Volume: 7
Issue: 1
Pages: 6145
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Publication
33774866 | J:348712
First Author: Zhong BR
Year: 2021
Journal: FASEB J
Title: TUFM is involved in Alzheimer's disease-like pathologies that are associated with ROS.
Volume: 35
Issue: 5
Pages: e21445
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Publication
28603494 | J:275603
 
First Author: Wang X
Year: 2017
Journal: Front Aging Neurosci
Title: YXQN Reduces Alzheimer's Disease-Like Pathology and Cognitive Decline in APPswePS1dE9 Transgenic Mice.
Volume: 9
Pages: 157
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Publication
19625507 | J:151798
First Author: Shi Q
Year: 2009
Journal: J Neurosci
Title: Reduced amyloid deposition in mice overexpressing RTN3 is adversely affected by preformed dystrophic neurites.
Volume: 29
Issue: 29
Pages: 9163-73
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Publication
32860886 | J:299161
 
First Author: Zhang W
Year: 2020
Journal: Neurosci Lett
Title: FoxO1 overexpression reduces Aβ production and tau phosphorylation in vitro.
Volume: 738
Pages: 135322
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Publication
30596517 | J:288812
First Author: Wang T
Year: 2019
Journal: FASEB J
Title: BAP31 deficiency contributes to the formation of amyloid-β plaques in Alzheimer's disease by reducing the stability of RTN3.
Volume: 33
Issue: 4
Pages: 4936-4946
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Publication
38729552 | J:349329
 
First Author: Li CL
Year: 2024
Journal: Exp Neurol
Title: STAU1 exhibits a dual function by promoting amyloidogenesis and tau phosphorylation in cultured cells.
Volume: 377
Pages: 114805
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Publication
24146979 | J:209106
First Author: Devi L
Year: 2013
Journal: PLoS One
Title: Deletion of the eIF2α Kinase GCN2 fails to rescue the memory decline associated with Alzheimer's disease.
Volume: 8
Issue: 10
Pages: e77335
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Publication
27192432 | J:248962
First Author: Walker KR
Year: 2016
Journal: PLoS One
Title: Genetic Deletion of the Clathrin Adaptor GGA3 Reduces Anxiety and Alters GABAergic Transmission.
Volume: 11
Issue: 5
Pages: e0155799
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22221883 | J:188312
First Author: Fuso A
Year: 2012
Journal: Neurobiol Aging
Title: S-adenosylmethionine reduces the progress of the Alzheimer-like features induced by B-vitamin deficiency in mice.
Volume: 33
Issue: 7
Pages: 1482.e1-16
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Publication
30576233 | J:284806
First Author: Qian Q
Year: 2019
Journal: FASEB J
Title: Down-regulated expression of microRNA-338-5p contributes to neuropathology in Alzheimer's disease.
Volume: 33
Issue: 3
Pages: 4404-4417
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Publication
31743728 | J:307433
 
First Author: Peterman JL
Year: 2020
Journal: Behav Brain Res
Title: Prolonged isolation stress accelerates the onset of Alzheimer's disease-related pathology in 5xFAD mice despite running wheels and environmental enrichment.
Volume: 379
Pages: 112366
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Publication
25378159 | J:238184
First Author: Zhang J
Year: 2014
Journal: J Neurosci
Title: Synaptic and cognitive improvements by inhibition of 2-AG metabolism are through upregulation of microRNA-188-3p in a mouse model of Alzheimer's disease.
Volume: 34
Issue: 45
Pages: 14919-33
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34232542 | J:350384
First Author: Liu J
Year: 2021
Journal: Cell Prolif
Title: Infusion of hESC derived Immunity-and-matrix regulatory cells improves cognitive ability in early-stage AD mice.
Volume: 54
Issue: 8
Pages: e13085
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24305806 | J:255339
First Author: Herskowitz JH
Year: 2013
Journal: J Neurosci
Title: Pharmacologic inhibition of ROCK2 suppresses amyloid-β production in an Alzheimer's disease mouse model.
Volume: 33
Issue: 49
Pages: 19086-98
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Publication
29033830 | J:276673
 
First Author: Guglielmotto M
Year: 2017
Journal: Front Aging Neurosci
Title: The Decrease of Uch-L1 Activity Is a Common Mechanism Responsible for Aβ 42 Accumulation in Alzheimer's and Vascular Disease.
Volume: 9
Pages: 320
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Publication
36427805 | J:344587
 
First Author: Feng W
Year: 2023
Journal: Brain Behav Immun
Title: B lymphocytes ameliorate Alzheimer's disease-like neuropathology via interleukin-35.
Volume: 108
Pages: 16-31
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Publication
32918367 | J:352666
First Author: Yao Y
Year: 2020
Journal: Alzheimers Dement
Title: Correction of microtubule defects within Aβ plaque-associated dystrophic axons results in lowered Aβ release and plaque deposition.
Volume: 16
Issue: 10
Pages: 1345-1357
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Publication
27312991 | J:264480
First Author: Kolisnyk B
Year: 2017
Journal: Cereb Cortex
Title: Cholinergic Surveillance over Hippocampal RNA Metabolism and Alzheimer's-Like Pathology.
Volume: 27
Issue: 7
Pages: 3553-3567
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Publication
27993242 | J:239385
First Author: Gannon PJ
Year: 2017
Journal: Am J Pathol
Title: HIV Protease Inhibitors Alter Amyloid Precursor Protein Processing via β-Site Amyloid Precursor Protein Cleaving Enzyme-1 Translational Up-Regulation.
Volume: 187
Issue: 1
Pages: 91-109
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Publication
22294787 | J:237165
First Author: Lakshmana MK
Year: 2012
Journal: FASEB J
Title: Role of RanBP9 on amyloidogenic processing of APP and synaptic protein levels in the mouse brain.
Volume: 26
Issue: 5
Pages: 2072-83
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Publication
23259059 | J:192876
First Author: Wang CL
Year: 2012
Journal: Biol Open
Title: VPS35 regulates developing mouse hippocampal neuronal morphogenesis by promoting retrograde trafficking of BACE1.
Volume: 1
Issue: 12
Pages: 1248-57
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Publication
25316600 | J:218405
First Author: Cox CJ
Year: 2015
Journal: Neurobiol Aging
Title: Dietary (-)-epicatechin as a potent inhibitor of βγ-secretase amyloid precursor protein processing.
Volume: 36
Issue: 1
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