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Search results 301 to 400 out of 823 for Brca1

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Type Details Score
Publication
22539352 | J:188388
First Author: Wu J
Year: 2012
Journal: J Biol Chem
Title: RAP80 protein is important for genomic stability and is required for stabilizing BRCA1-A complex at DNA damage sites in vivo.
Volume: 287
Issue: 27
Pages: 22919-26
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Publication
12557227 | J:81488
First Author: Hohenstein P
Year: 2003
Journal: Genes Chromosomes Cancer
Title: Serrated adenomas and mixed polyposis caused by a splice acceptor deletion in the mouse Smad4 gene.
Volume: 36
Issue: 3
Pages: 273-82
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Publication
11704837 | J:73006
First Author: Robinson GW
Year: 2001
Journal: Oncogene
Title: Functional mammary gland development and oncogene-induced tumor formation are not affected by the absence of the retinoblastoma gene.
Volume: 20
Issue: 48
Pages: 7115-9
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Publication
21846369 | J:216041
First Author: Zhu M
Year: 2011
Journal: Genome Biol
Title: Integrated miRNA and mRNA expression profiling of mouse mammary tumor models identifies miRNA signatures associated with mammary tumor lineage.
Volume: 12
Issue: 8
Pages: R77
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Publication
28297660 | J:251186
First Author: Wu NY
Year: 2017
Journal: Cell Rep
Title: Progesterone Prevents High-Grade Serous Ovarian Cancer by Inducing Necroptosis of p53-Defective Fallopian Tube Epithelial Cells.
Volume: 18
Issue: 11
Pages: 2557-2565
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Publication
27625309 | J:241726
First Author: Huang HS
Year: 2016
Journal: J Pathol
Title: Haemoglobin in pelvic fluid rescues Fallopian tube epithelial cells from reactive oxygen species stress and apoptosis.
Volume: 240
Issue: 4
Pages: 484-494
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Publication
26363031 | J:226629
First Author: Huang HS
Year: 2015
Journal: Carcinogenesis
Title: Mutagenic, surviving and tumorigenic effects of follicular fluid in the context of p53 loss: initiation of fimbria carcinogenesis.
Volume: 36
Issue: 11
Pages: 1419-28
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Publication
22915751 | J:193222
First Author: Juvekar A
Year: 2012
Journal: Cancer Discov
Title: Combining a PI3K inhibitor with a PARP inhibitor provides an effective therapy for BRCA1-related breast cancer.
Volume: 2
Issue: 11
Pages: 1048-63
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Publication
23243027 | J:194364
First Author: Balboni AL
Year: 2013
Journal: Cancer Res
Title: ΔNp63α-mediated activation of bone morphogenetic protein signaling governs stem cell activity and plasticity in normal and malignant mammary epithelial cells.
Volume: 73
Issue: 2
Pages: 1020-30
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Publication
11156526 | J:67113
First Author: Hutchinson JN
Year: 2000
Journal: Oncogene
Title: Transgenic mouse models of human breast cancer.
Volume: 19
Issue: 53
Pages: 6130-7
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Publication
32840210 | J:308026
   
First Author: Yeo SK
Year: 2020
Journal: Elife
Title: Single-cell RNA-sequencing reveals distinct patterns of cell state heterogeneity in mouse models of breast cancer.
Volume: 9
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Publication
17626183 | J:126564
First Author: Rottenberg S
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Selective induction of chemotherapy resistance of mammary tumors in a conditional mouse model for hereditary breast cancer.
Volume: 104
Issue: 29
Pages: 12117-22
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Publication
37943878 | J:342352
First Author: He A
Year: 2023
Journal: PLoS Biol
Title: Targeted inhibition of Wnt signaling with a Clostridioides difficile toxin B fragment suppresses breast cancer tumor growth.
Volume: 21
Issue: 11
Pages: e3002353
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Publication
23246963 | J:204879
First Author: Montero JC
Year: 2014
Journal: Oncogene
Title: Active kinase profiling, genetic and pharmacological data define mTOR as an important common target in triple-negative breast cancer.
Volume: 33
Issue: 2
Pages: 148-56
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Publication
31233030 | J:309462
   
First Author: Xiang D
Year: 2019
Journal: J Vis Exp
Title: Modeling Breast Cancer via an Intraductal Injection of Cre-expressing Adenovirus into the Mouse Mammary Gland.
Issue: 148
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Publication
28278054 | J:274980
First Author: Scott A
Year: 2017
Journal: Cell Cycle
Title: p16 loss rescues functional decline of Brca1-deficient mammary stem cells.
Volume: 16
Issue: 8
Pages: 759-764
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Publication
15232000 | J:91442
First Author: Hamatani T
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Global gene expression analysis identifies molecular pathways distinguishing blastocyst dormancy and activation.
Volume: 101
Issue: 28
Pages: 10326-31
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Publication
29109428 | J:256938
First Author: Breitkopf SB
Year: 2017
Journal: Sci Rep
Title: Serial-omics of P53-/-, Brca1-/- Mouse Breast Tumor and Normal Mammary Gland.
Volume: 7
Issue: 1
Pages: 14503
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Publication
33969421 | J:306545
 
First Author: Tsang SM
Year: 2021
Journal: Dis Model Mech
Title: Sox11 regulates mammary tumour-initiating and metastatic capacity in Brca1-deficient mouse mammary tumour cells.
Volume: 14
Issue: 5
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Publication
33798452 | J:314103
First Author: Ulmke PA
Year: 2021
Journal: Stem Cell Reports
Title: Molecular Profiling Reveals Involvement of ESCO2 in Intermediate Progenitor Cell Maintenance in the Developing Mouse Cortex.
Volume: 16
Issue: 4
Pages: 968-984
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Publication
26774285 | J:231089
First Author: Tkáč J
Year: 2016
Journal: Mol Cell
Title: HELB Is a Feedback Inhibitor of DNA End Resection.
Volume: 61
Issue: 3
Pages: 405-418
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Publication
9419374 | J:45976
First Author: de Lecea L
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity.
Volume: 95
Issue: 1
Pages: 322-7
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Publication
36480166 | J:331888
 
First Author: Edwards SC
Year: 2023
Journal: J Exp Med
Title: PD-1 and TIM-3 differentially regulate subsets of mouse IL-17A-producing γδ T cells.
Volume: 220
Issue: 2
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Publication
25176624 | J:214799
First Author: Fabris VT
Year: 2014
Journal: Cancer Genet
Title: From chromosomal abnormalities to the identification of target genes in mouse models of breast cancer.
Volume: 207
Issue: 6
Pages: 233-46
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Publication
28592566 | J:252847
 
First Author: Nolan E
Year: 2017
Journal: Sci Transl Med
Title: Combined immune checkpoint blockade as a therapeutic strategy for BRCA1-mutated breast cancer.
Volume: 9
Issue: 393
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Publication
37207276 | J:335835
First Author: Zeng J
Year: 2023
Journal: iScience
Title: Dichotomous ovarian cancer-initiating potential of Pax8+ cells revealed by a mouse genetic mosaic model.
Volume: 26
Issue: 5
Pages: 106742
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Publication
24120138 | J:205213
First Author: Israelsen WJ
Year: 2013
Journal: Cell
Title: PKM2 isoform-specific deletion reveals a differential requirement for pyruvate kinase in tumor cells.
Volume: 155
Issue: 2
Pages: 397-409
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Publication
38171333 | J:351130
First Author: Zhang Y
Year: 2024
Journal: Cell Metab
Title: Metabolic switch regulates lineage plasticity and induces synthetic lethality in triple-negative breast cancer.
Volume: 36
Issue: 1
Pages: 193-208.e8
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Publication
31653568 | J:286257
First Author: Callen E
Year: 2020
Journal: Mol Cell
Title: 53BP1 Enforces Distinct Pre- and Post-resection Blocks on Homologous Recombination.
Volume: 77
Issue: 1
Pages: 26-38.e7
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Publication
31704972 | J:336875
First Author: Nie L
Year: 2019
Journal: Nat Commun
Title: CDK2-mediated site-specific phosphorylation of EZH2 drives and maintains triple-negative breast cancer.
Volume: 10
Issue: 1
Pages: 5114
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Publication
22445450 | J:183456
First Author: Seminotti B
Year: 2012
Journal: Mol Genet Metab
Title: Induction of oxidative stress in brain of glutaryl-CoA dehydrogenase deficient mice by acute lysine administration.
Volume: 106
Issue: 1
Pages: 31-8
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Publication
33621853 | J:334508
First Author: Dúcka M
Year: 2021
Journal: Neoplasia
Title: c-Myb interferes with inflammatory IL1α-NF-κB pathway in breast cancer cells.
Volume: 23
Issue: 3
Pages: 326-336
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Publication
27550455 | J:236246
First Author: Oplustil O'Connor L
Year: 2016
Journal: Cancer Res
Title: The PARP Inhibitor AZD2461 Provides Insights into the Role of PARP3 Inhibition for Both Synthetic Lethality and Tolerability with Chemotherapy in Preclinical Models.
Volume: 76
Issue: 20
Pages: 6084-6094
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Publication
30674894 | J:276500
First Author: Annunziato S
Year: 2019
Journal: Nat Commun
Title: Comparative oncogenomics identifies combinations of driver genes and drug targets in BRCA1-mutated breast cancer.
Volume: 10
Issue: 1
Pages: 397
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Publication
29894693 | J:262541
First Author: Gogola E
Year: 2018
Journal: Cancer Cell
Title: Selective Loss of PARG Restores PARylation and Counteracts PARP Inhibitor-Mediated Synthetic Lethality.
Volume: 33
Issue: 6
Pages: 1078-1093.e12
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Publication
32513774 | J:293698
First Author: Liu H
Year: 2020
Journal: Cancer Discov
Title: The INPP4B Tumor Suppressor Modulates EGFR Trafficking and Promotes Triple-Negative Breast Cancer.
Volume: 10
Issue: 8
Pages: 1226-1239
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Publication
32580962 | J:296305
First Author: Okamoto T
Year: 2020
Journal: Cancer Res
Title: FIP200 Suppresses Immune Checkpoint Therapy Responses in Breast Cancers by Limiting AZI2/TBK1/IRF Signaling Independent of Its Canonical Autophagy Function.
Volume: 80
Issue: 17
Pages: 3580-3592
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Publication
33857404 | J:307190
First Author: Shinoda K
Year: 2021
Journal: Mol Cell
Title: The dystonia gene THAP1 controls DNA double-strand break repair choice.
Volume: 81
Issue: 12
Pages: 2611-2624.e10
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Publication
18451150 | J:134612
First Author: Shafee N
Year: 2008
Journal: Cancer Res
Title: Cancer stem cells contribute to cisplatin resistance in Brca1/p53-mediated mouse mammary tumors.
Volume: 68
Issue: 9
Pages: 3243-50
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Publication
30174241 | J:265467
First Author: Dravis C
Year: 2018
Journal: Cancer Cell
Title: Epigenetic and Transcriptomic Profiling of Mammary Gland Development and Tumor Models Disclose Regulators of Cell State Plasticity.
Volume: 34
Issue: 3
Pages: 466-482.e6
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15485900 | J:94149
First Author: Stark JM
Year: 2004
Journal: Mol Cell Biol
Title: Genetic steps of mammalian homologous repair with distinct mutagenic consequences.
Volume: 24
Issue: 21
Pages: 9305-16
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7501018 | J:30140
First Author: Ramírez-Solis R
Year: 1995
Journal: Nature
Title: Chromosome engineering in mice.
Volume: 378
Issue: 6558
Pages: 720-4
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10087300 | J:54121
First Author: Nasir J
Year: 1999
Journal: Mamm Genome
Title: Chromosomal localization of the Huntingtin associated protein (HAP-1) gene in mouse and humans with radiation hybrid and interspecific backcross mapping.
Volume: 10
Issue: 4
Pages: 397-8
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Publication
16179389 | J:101404
First Author: Monaco L
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Inhibition of Aurora-B kinase activity by poly(ADP-ribosyl)ation in response to DNA damage.
Volume: 102
Issue: 40
Pages: 14244-8
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Publication
9063750 | J:38616
First Author: Connor F
Year: 1997
Journal: Hum Mol Genet
Title: Cloning, chromosomal mapping and expression pattern of the mouse Brca2 gene.
Volume: 6
Issue: 2
Pages: 291-300
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11934988 | J:76360
First Author: Celeste A
Year: 2002
Journal: Science
Title: Genomic instability in mice lacking histone H2AX.
Volume: 296
Issue: 5569
Pages: 922-7
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Publication
23039116 | J:192634
First Author: Kogo H
Year: 2012
Journal: Genes Cells
Title: HORMAD2 is essential for synapsis surveillance during meiotic prophase via the recruitment of ATR activity.
Volume: 17
Issue: 11
Pages: 897-912
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Publication
22549958 | J:183982
First Author: Wojtasz L
Year: 2012
Journal: Genes Dev
Title: Meiotic DNA double-strand breaks and chromosome asynapsis in mice are monitored by distinct HORMAD2-independent and -dependent mechanisms.
Volume: 26
Issue: 9
Pages: 958-73
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Publication
31839538 | J:284005
First Author: Dokshin GA
Year: 2020
Journal: Dev Cell
Title: GCNA Interacts with Spartan and Topoisomerase II to Regulate Genome Stability.
Volume: 52
Issue: 1
Pages: 53-68.e6
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Publication
20080676 | J:157596
First Author: An JY
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: UBR2 mediates transcriptional silencing during spermatogenesis via histone ubiquitination.
Volume: 107
Issue: 5
Pages: 1912-7
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Publication
12573259 | J:81512
First Author: Qian J
Year: 2003
Journal: Genomics
Title: Mouse Wnt9b transforming activity, tissue-specific expression, and evolution.
Volume: 81
Issue: 1
Pages: 34-46
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Publication
38816652 | J:357390
First Author: Wiesheu R
Year: 2024
Journal: EMBO J
Title: IL-27 maintains cytotoxic Ly6C(+) γδ T cells that arise from immature precursors.
Volume: 43
Issue: 14
Pages: 2878-2907
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Publication
34090924 | J:307149
 
First Author: Regua AT
Year: 2021
Journal: Cancer Lett
Title: Transgenic mouse models of breast cancer.
Volume: 516
Pages: 73-83
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Publication
24220145 | J:227323
First Author: Pfefferle AD
Year: 2013
Journal: Genome Biol
Title: Transcriptomic classification of genetically engineered mouse models of breast cancer identifies human subtype counterparts.
Volume: 14
Issue: 11
Pages: R125
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Publication
34879282 | J:320927
First Author: Hanasoge Somasundara AV
Year: 2021
Journal: Cell Rep
Title: Parity-induced changes to mammary epithelial cells control NKT cell expansion and mammary oncogenesis.
Volume: 37
Issue: 10
Pages: 110099
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Publication
18663141 | J:139518
First Author: Mahadevaiah SK
Year: 2008
Journal: J Cell Biol
Title: Extensive meiotic asynapsis in mice antagonises meiotic silencing of unsynapsed chromatin and consequently disrupts meiotic sex chromosome inactivation.
Volume: 182
Issue: 2
Pages: 263-76
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Publication
27653681 | J:239126
First Author: Zhang Z
Year: 2016
Journal: Cell Rep
Title: Mammary-Stem-Cell-Based Somatic Mouse Models Reveal Breast Cancer Drivers Causing Cell Fate Dysregulation.
Volume: 16
Issue: 12
Pages: 3146-3156
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Publication
26916217 | J:259917
 
First Author: Du W
Year: 2016
Journal: Sci Rep
Title: Hyper-active non-homologous end joining selects for synthetic lethality resistant and pathological Fanconi anemia hematopoietic stem and progenitor cells.
Volume: 6
Pages: 22167
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Publication
31367040 | J:283289
First Author: Wellenstein MD
Year: 2019
Journal: Nature
Title: Loss of p53 triggers WNT-dependent systemic inflammation to drive breast cancer metastasis.
Volume: 572
Issue: 7770
Pages: 538-542
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Publication
27798604 | J:246818
First Author: Blaas L
Year: 2016
Journal: Nat Cell Biol
Title: Lgr6 labels a rare population of mammary gland progenitor cells that are able to originate luminal mammary tumours.
Volume: 18
Issue: 12
Pages: 1346-1356
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Publication
23103855 | J:193631
First Author: Jaspers JE
Year: 2013
Journal: Cancer Discov
Title: Loss of 53BP1 causes PARP inhibitor resistance in Brca1-mutated mouse mammary tumors.
Volume: 3
Issue: 1
Pages: 68-81
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Publication
22767648 | J:320930
First Author: Zander SA
Year: 2012
Journal: Cancer Prev Res (Phila)
Title: Lack of ABCG2 shortens latency of BRCA1-deficient mammary tumors and this is not affected by genistein or resveratrol.
Volume: 5
Issue: 8
Pages: 1053-60
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Publication
30540933 | J:271132
First Author: Ding L
Year: 2018
Journal: Cell Rep
Title: PARP Inhibition Elicits STING-Dependent Antitumor Immunity in Brca1-Deficient Ovarian Cancer.
Volume: 25
Issue: 11
Pages: 2972-2980.e5
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Publication
27340177 | J:233376
First Author: Annunziato S
Year: 2016
Journal: Genes Dev
Title: Modeling invasive lobular breast carcinoma by CRISPR/Cas9-mediated somatic genome editing of the mammary gland.
Volume: 30
Issue: 12
Pages: 1470-80
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Publication
30393076 | J:272558
First Author: Hirota T
Year: 2018
Journal: Dev Cell
Title: SETDB1 Links the Meiotic DNA Damage Response to Sex Chromosome Silencing in Mice.
Volume: 47
Issue: 5
Pages: 645-659.e6
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Publication
30456390 | J:287931
First Author: Pitarresi JR
Year: 2018
Journal: Life Sci Alliance
Title: Disruption of stromal hedgehog signaling initiates RNF5-mediated proteasomal degradation of PTEN and accelerates pancreatic tumor growth.
Volume: 1
Issue: 5
Pages: e201800190
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Publication
23204224 | J:194376
First Author: Shakya R
Year: 2013
Journal: Cancer Res
Title: Hypomethylating therapy in an aggressive stroma-rich model of pancreatic carcinoma.
Volume: 73
Issue: 2
Pages: 885-96
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Publication
9799267 | J:50799
First Author: Liu P
Year: 1998
Journal: Genetics
Title: Embryonic lethality and tumorigenesis caused by segmental aneuploidy on mouse chromosome 11.
Volume: 150
Issue: 3
Pages: 1155-68
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- | J:188992
     
First Author: The Netherlands Cancer Institute
Year: 2012
Journal: MGI Direct Data Submission
Title: Direct data submission by The Netherlands Cancer Institute
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Publication
9096121 | J:39309
First Author: Rajan L
Year: 1997
Journal: Mamm Genome
Title: An MMTV integration site maps near the distal end of mouse chromosome 11.
Volume: 8
Issue: 4
Pages: 295-6
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21459848 | J:182963
First Author: Laulier C
Year: 2011
Journal: Nucleic Acids Res
Title: The relative efficiency of homology-directed repair has distinct effects on proper anaphase chromosome separation.
Volume: 39
Issue: 14
Pages: 5935-44
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Publication
24913804 | J:215685
First Author: Lamparter C
Year: 2014
Journal: Toxicol Sci
Title: Tissue-specific effects of valproic acid on DNA repair genes and apoptosis in postimplantation mouse embryos.
Volume: 141
Issue: 1
Pages: 59-67
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22172717 | J:178600
First Author: Patel KJ
Year: 2011
Journal: Cancer Cell
Title: "Ring-fencing" BRCA1 tumor suppressor activity.
Volume: 20
Issue: 6
Pages: 693-5
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16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
31242413 | J:294372
First Author: Brandsma I
Year: 2019
Journal: Cell Rep
Title: HSF2BP Interacts with a Conserved Domain of BRCA2 and Is Required for Mouse Spermatogenesis.
Volume: 27
Issue: 13
Pages: 3790-3798.e7
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20551173 | J:161203
First Author: Kumar R
Year: 2010
Journal: Genes Dev
Title: Functional conservation of Mei4 for meiotic DNA double-strand break formation from yeasts to mice.
Volume: 24
Issue: 12
Pages: 1266-80
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11711534 | J:73962
First Author: Seykora JT
Year: 2002
Journal: J Biol Chem
Title: 'Srcasm: a novel Src activating and signaling molecule.
Volume: 277
Issue: 4
Pages: 2812-22
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28115467 | J:238694
First Author: Gong Y
Year: 2017
Journal: Genes Dev
Title: PHF11 promotes DSB resection, ATR signaling, and HR.
Volume: 31
Issue: 1
Pages: 46-58
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Publication
16951165 | J:113389
First Author: Hulit J
Year: 2006
Journal: Cancer Res
Title: p27Kip1 repression of ErbB2-induced mammary tumor growth in transgenic mice involves Skp2 and Wnt/beta-catenin signaling.
Volume: 66
Issue: 17
Pages: 8529-41
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28608929 | J:247957
First Author: Zhai Y
Year: 2017
Journal: J Pathol
Title: High-grade serous carcinomas arise in the mouse oviduct via defects linked to the human disease.
Volume: 243
Issue: 1
Pages: 16-25
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Publication
26443207 | J:227197
First Author: Jacome A
Year: 2015
Journal: EMBO J
Title: NSMCE2 suppresses cancer and aging in mice independently of its SUMO ligase activity.
Volume: 34
Issue: 21
Pages: 2604-19
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Publication
26658019 | J:242195
First Author: Juan HC
Year: 2016
Journal: Cell Death Differ
Title: Cdk12 is essential for embryonic development and the maintenance of genomic stability.
Volume: 23
Issue: 6
Pages: 1038-48
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Publication
12913077 | J:85108
First Author: Wong JC
Year: 2003
Journal: Hum Mol Genet
Title: Targeted disruption of exons 1 to 6 of the Fanconi Anemia group A gene leads to growth retardation, strain-specific microphthalmia, meiotic defects and primordial germ cell hypoplasia.
Volume: 12
Issue: 16
Pages: 2063-76
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Publication
36546838 | J:336101
First Author: Dickinson K
Year: 2023
Journal: Am J Physiol Renal Physiol
Title: WT1 regulates expression of DNA repair gene Neil3 during nephrogenesis.
Volume: 324
Issue: 3
Pages: F245-F255
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Publication
31541646 | J:288654
First Author: Lun MP
Year: 2019
Journal: Am J Pathol
Title: Spatiotemporal Gradient of Cortical Neuron Death Contributes to Microcephaly in Knock-In Mouse Model of Ligase 4 Syndrome.
Volume: 189
Issue: 12
Pages: 2440-2449
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