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Search results 301 to 400 out of 1236 for Cdkn2a

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Type Details Score
Publication
12007978 | J:77200
First Author: Tada T
Year: 2002
Journal: J Neurosci Methods
Title: A head holder for magnetic resonance imaging that allows the stereotaxic alignment of spontaneously occurring intracranial mouse tumors.
Volume: 116
Issue: 1
Pages: 1-7
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Publication
15021904 | J:89926
First Author: Zhang Z
Year: 2004
Journal: Oncogene
Title: Cancer chemopreventive activity of a mixture of Chinese herbs (antitumor B) in mouse lung tumor models.
Volume: 23
Issue: 21
Pages: 3841-50
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Publication
22952867 | J:191654
First Author: Liu J
Year: 2012
Journal: PLoS One
Title: Induction of histiocytic sarcoma in mouse skeletal muscle.
Volume: 7
Issue: 8
Pages: e44044
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Publication
21526190 | J:172271
First Author: Altomare DA
Year: 2011
Journal: PLoS One
Title: Losses of both products of the Cdkn2a/Arf locus contribute to asbestos-induced mesothelioma development and cooperate to accelerate tumorigenesis.
Volume: 6
Issue: 4
Pages: e18828
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Publication
11602205 | J:101676
First Author: Pantoja C
Year: 2001
Journal: Exp Gerontol
Title: Identification of the gene immediately downstream of the murine INK4a/ARF locus.
Volume: 36
Issue: 8
Pages: 1289-302
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Publication
19723896 | J:349024
First Author: Boquoi A
Year: 2009
Journal: Cancer Prev Res (Phila)
Title: Chemoprevention of mouse intestinal tumorigenesis by the cyclin-dependent kinase inhibitor SNS-032.
Volume: 2
Issue: 9
Pages: 800-6
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Publication
28286271 | J:251357
First Author: Lv F
Year: 2017
Journal: Biochem Biophys Res Commun
Title: p16 deficiency promotes nonalcoholic steatohepatitis via regulation of hepatic oxidative stress.
Volume: 486
Issue: 2
Pages: 264-269
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Publication
29447461 | J:279002
First Author: Sundar IK
Year: 2018
Journal: Am J Respir Cell Mol Biol
Title: Genetic Ablation of p16INK4a Does Not Protect against Cellular Senescence in Mouse Models of Chronic Obstructive Pulmonary Disease/Emphysema.
Volume: 59
Issue: 2
Pages: 189-199
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Publication
25395428 | J:220776
First Author: Xu B
Year: 2015
Journal: Blood
Title: Selective inhibition of EZH2 and EZH1 enzymatic activity by a small molecule suppresses MLL-rearranged leukemia.
Volume: 125
Issue: 2
Pages: 346-57
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Publication
10375589 | J:113072
First Author: Orlow I
Year: 1999
Journal: Int J Oncol
Title: Involvement of the Ink4a gene (p16 and p19arf) in murine tumorigenesis.
Volume: 15
Issue: 1
Pages: 17-24
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Publication
37097751 | J:349059
 
First Author: Guijarro MV
Year: 2023
Journal: JCI Insight
Title: First-in-class multifunctional TYMS nonclassical antifolate inhibitor with potent in vivo activity that prolongs survival.
Volume: 8
Issue: 10
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Publication
15888328 | J:98234
First Author: Sung YH
Year: 2005
Journal: Mech Ageing Dev
Title: Hematopoietic malignancies associated with increased Stat5 and Bcl-x(L) expressions in Ink4a/Arf-deficient mice.
Volume: 126
Issue: 6-7
Pages: 732-9
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Publication
25209293 | J:318275
First Author: Price JD
Year: 2014
Journal: J Neurosci
Title: The Ink4a/Arf locus is a barrier to direct neuronal transdifferentiation.
Volume: 34
Issue: 37
Pages: 12560-7
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Publication
20197468 | J:157980
First Author: Becher OJ
Year: 2010
Journal: Cancer Res
Title: Preclinical evaluation of radiation and perifosine in a genetically and histologically accurate model of brainstem glioma.
Volume: 70
Issue: 6
Pages: 2548-57
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Publication
14724566 | J:88365
First Author: Sharpless NE
Year: 2004
Journal: Oncogene
Title: The differential impact of p16(INK4a) or p19(ARF) deficiency on cell growth and tumorigenesis.
Volume: 23
Issue: 2
Pages: 379-85
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Publication
28249168 | J:256196
First Author: Rajbhandari N
Year: 2017
Journal: Cell Rep
Title: Autocrine IGF1 Signaling Mediates Pancreatic Tumor Cell Dormancy in the Absence of Oncogenic Drivers.
Volume: 18
Issue: 9
Pages: 2243-2255
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Publication
18472967 | J:138670
First Author: Lyustikman Y
Year: 2008
Journal: Neoplasia
Title: Constitutive activation of Raf-1 induces glioma formation in mice.
Volume: 10
Issue: 5
Pages: 501-10
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21975932 | J:178004
First Author: Jin X
Year: 2011
Journal: Cancer Res
Title: EGFR-AKT-Smad signaling promotes formation of glioma stem-like cells and tumor angiogenesis by ID3-driven cytokine induction.
Volume: 71
Issue: 22
Pages: 7125-34
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Publication
39365700 | J:358059
First Author: Schmid S
Year: 2024
Journal: Cell Rep
Title: ERK signaling promotes resistance to TRK kinase inhibition in NTRK fusion-driven glioma mouse models.
Volume: 43
Issue: 10
Pages: 114829
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Publication
26075792 | J:231851
First Author: Mohankumar KM
Year: 2015
Journal: Nat Genet
Title: An in vivo screen identifies ependymoma oncogenes and tumor-suppressor genes.
Volume: 47
Issue: 8
Pages: 878-87
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Publication
39255775 | J:358824
First Author: Watson SS
Year: 2024
Journal: Cancer Cell
Title: Fibrotic response to anti-CSF-1R therapy potentiates glioblastoma recurrence.
Volume: 42
Issue: 9
Pages: 1507-1527.e11
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Publication
19079609 | J:144358
First Author: Jeong JH
Year: 2008
Journal: PLoS One
Title: BRAF activation initiates but does not maintain invasive prostate adenocarcinoma.
Volume: 3
Issue: 12
Pages: e3949
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Publication
14982856 | J:88435
First Author: Yang C
Year: 2004
Journal: Am J Pathol
Title: The role of the cyclin D1-dependent kinases in ErbB2-mediated breast cancer.
Volume: 164
Issue: 3
Pages: 1031-8
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Publication
20676132 | J:165295
First Author: Shimizu T
Year: 2010
Journal: Oncogene
Title: c-MYC overexpression with loss of Ink4a/Arf transforms bone marrow stromal cells into osteosarcoma accompanied by loss of adipogenesis.
Volume: 29
Issue: 42
Pages: 5687-99
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Publication
10669005 | J:60497
First Author: Holland EC
Year: 2000
Journal: Toxicol Pathol
Title: A mouse model for glioma: biology, pathology, and therapeutic opportunities.
Volume: 28
Issue: 1
Pages: 171-7
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Publication
19826056 | J:154063
First Author: Galanzha EI
Year: 2009
Journal: Cancer Res
Title: In vivo, noninvasive, label-free detection and eradication of circulating metastatic melanoma cells using two-color photoacoustic flow cytometry with a diode laser.
Volume: 69
Issue: 20
Pages: 7926-34
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20577054 | J:163779
First Author: Johnson SM
Year: 2010
Journal: J Clin Invest
Title: Mitigation of hematologic radiation toxicity in mice through pharmacological quiescence induced by CDK4/6 inhibition.
Volume: 120
Issue: 7
Pages: 2528-36
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Publication
15572761 | J:94799
First Author: Sarkar-Agrawal P
Year: 2004
Journal: J Natl Cancer Inst
Title: Impaired processing of DNA photoproducts and ultraviolet hypermutability with loss of p16INK4a or p19ARF.
Volume: 96
Issue: 23
Pages: 1790-3
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Publication
17987514 | J:140820
First Author: Latendresse JR
Year: 2007
Journal: Toxicol Pathol
Title: Two cases of uveal amelanotic melanoma in transgenic Tyr-HRAS+ Ink4a/Arf heterozygous mice.
Volume: 35
Issue: 6
Pages: 827-32
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Publication
16322687 | J:107089
First Author: Gibson SL
Year: 2005
Journal: Cancer Biol Ther
Title: p16(Ink4a) inhibits histologic progression and angiogenic signaling in min colon tumors.
Volume: 4
Issue: 12
Pages: 1389-94
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Publication
21957175 | J:179999
First Author: Lee DH
Year: 2012
Journal: Am J Physiol Renal Physiol
Title: INK4a deletion results in improved kidney regeneration and decreased capillary rarefaction after ischemia-reperfusion injury.
Volume: 302
Issue: 1
Pages: F183-91
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Publication
32675324 | J:302217
First Author: Szulzewsky F
Year: 2020
Journal: Genes Dev
Title: Comparison of tumor-associated YAP1 fusions identifies a recurrent set of functions critical for oncogenesis.
Volume: 34
Issue: 15-16
Pages: 1051-1064
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Publication
22872574 | J:234392
First Author: Roberts PJ
Year: 2012
Journal: Clin Cancer Res
Title: Combined PI3K/mTOR and MEK inhibition provides broad antitumor activity in faithful murine cancer models.
Volume: 18
Issue: 19
Pages: 5290-303
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Publication
12907609 | J:84850
First Author: Wang Y
Year: 2003
Journal: Cancer Res
Title: Mice with alterations in both p53 and Ink4a/Arf display a striking increase in lung tumor multiplicity and progression: differential chemopreventive effect of budesonide in wild-type and mutant A/J mice.
Volume: 63
Issue: 15
Pages: 4389-95
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Publication
15016851 | J:89064
First Author: Sachs Z
Year: 2004
Journal: J Virol
Title: p16(Ink4a) interferes with Abelson virus transformation by enhancing apoptosis.
Volume: 78
Issue: 7
Pages: 3304-11
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Publication
12359767 | J:79689
First Author: Uhrbom L
Year: 2002
Journal: Cancer Res
Title: Ink4a-Arf loss cooperates with KRas activation in astrocytes and neural progenitors to generate glioblastomas of various morphologies depending on activated Akt.
Volume: 62
Issue: 19
Pages: 5551-8
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Publication
20861074 | J:166954
First Author: Wolstein JM
Year: 2010
Journal: Am J Physiol Renal Physiol
Title: INK4a knockout mice exhibit increased fibrosis under normal conditions and in response to unilateral ureteral obstruction.
Volume: 299
Issue: 6
Pages: F1486-95
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12407441 | J:79700
First Author: Koutcher JA
Year: 2002
Journal: Neoplasia
Title: MRI of mouse models for gliomas shows similarities to humans and can be used to identify mice for preclinical trials.
Volume: 4
Issue: 6
Pages: 480-5
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Publication
21118965 | J:166963
First Author: Sullivan JP
Year: 2010
Journal: Cancer Res
Title: Aldehyde dehydrogenase activity selects for lung adenocarcinoma stem cells dependent on notch signaling.
Volume: 70
Issue: 23
Pages: 9937-48
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Publication
11544531 | J:71394
First Author: Sharpless NE
Year: 2001
Journal: Nature
Title: Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis.
Volume: 413
Issue: 6851
Pages: 86-91
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Publication
23443342 | J:199028
First Author: Li M
Year: 2013
Journal: Leukemia
Title: Initially disadvantaged, TEL-AML1 cells expand and initiate leukemia in response to irradiation and cooperating mutations.
Volume: 27
Issue: 7
Pages: 1570-3
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Publication
16957738 | J:112956
First Author: Molofsky AV
Year: 2006
Journal: Nature
Title: Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageing.
Volume: 443
Issue: 7110
Pages: 448-52
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Publication
28915557 | J:349138
First Author: Tyagi E
Year: 2017
Journal: Oncotarget
Title: Loss of p16(INK4A) stimulates aberrant mitochondrial biogenesis through a CDK4/Rb-independent pathway.
Volume: 8
Issue: 34
Pages: 55848-55862
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Publication
27794120 | J:349133
First Author: Hayashi Y
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: BMP-SMAD-ID promotes reprogramming to pluripotency by inhibiting p16/INK4A-dependent senescence.
Volume: 113
Issue: 46
Pages: 13057-13062
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Publication
16957735 | J:112958
First Author: Janzen V
Year: 2006
Journal: Nature
Title: Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a.
Volume: 443
Issue: 7110
Pages: 421-6
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Publication
25061879 | J:215789
First Author: Yu DH
Year: 2014
Journal: J Clin Invest
Title: Targeted p16(Ink4a) epimutation causes tumorigenesis and reduces survival in mice.
Volume: 124
Issue: 9
Pages: 3708-12
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Publication
19667129 | J:153844
First Author: Yamakoshi K
Year: 2009
Journal: J Cell Biol
Title: Real-time in vivo imaging of p16Ink4a reveals cross talk with p53.
Volume: 186
Issue: 3
Pages: 393-407
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Publication
37928906 | J:342417
 
First Author: Micheli L
Year: 2023
Journal: Front Cell Dev Biol
Title: Transcriptome analysis reveals genes associated with stem cell activation by physical exercise in the dentate gyrus of aged p16Ink4a knockout mice.
Volume: 11
Pages: 1270892
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12538879 | J:81833
First Author: Kannan K
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Components of the Rb pathway are critical targets of UV mutagenesis in a murine melanoma model.
Volume: 100
Issue: 3
Pages: 1221-5
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16491120 | J:144141
First Author: Bianchi T
Year: 2006
Journal: Oncogene
Title: The tumor suppressor p16Ink4a regulates T lymphocyte survival.
Volume: 25
Issue: 29
Pages: 4110-5
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32194051 | J:300634
First Author: Ishida K
Year: 2020
Journal: Am J Pathol
Title: Specific Deletion of p16INK4a with Retention of p19ARF Enhances the Development of Invasive Oral Squamous Cell Carcinoma.
Volume: 190
Issue: 6
Pages: 1332-1342
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30792628 | J:276770
 
First Author: Micheli L
Year: 2019
Journal: Front Cell Neurosci
Title: p16Ink4a Prevents the Activation of Aged Quiescent Dentate Gyrus Stem Cells by Physical Exercise.
Volume: 13
Pages: 10
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23190892 | J:348805
First Author: Jenkins NC
Year: 2013
Journal: J Invest Dermatol
Title: Familial melanoma-associated mutations in p16 uncouple its tumor-suppressor functions.
Volume: 133
Issue: 4
Pages: 1043-51
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12902988 | J:85075
First Author: Sharpless NE
Year: 2003
Journal: Oncogene
Title: Both products of the mouse Ink4a/Arf locus suppress melanoma formation in vivo.
Volume: 22
Issue: 32
Pages: 5055-9
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29123081 | J:255077
First Author: Zhu J
Year: 2017
Journal: Nat Commun
Title: Resistance to cancer immunotherapy mediated by apoptosis of tumor-infiltrating lymphocytes.
Volume: 8
Issue: 1
Pages: 1404
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21811640 | J:174923
First Author: Soudja SM
Year: 2011
Journal: PLoS One
Title: Disrupted lymph node and splenic stroma in mice with induced inflammatory melanomas is associated with impaired recruitment of T and dendritic cells.
Volume: 6
Issue: 7
Pages: e22639
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20406967 | J:159458
First Author: Soudja SM
Year: 2010
Journal: Cancer Res
Title: Tumor-initiated inflammation overrides protective adaptive immunity in an induced melanoma model in mice.
Volume: 70
Issue: 9
Pages: 3515-25
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22343901 | J:182598
First Author: Lu C
Year: 2012
Journal: Nature
Title: IDH mutation impairs histone demethylation and results in a block to cell differentiation.
Volume: 483
Issue: 7390
Pages: 474-8
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37079217 | J:342853
First Author: Cherry C
Year: 2023
Journal: Geroscience
Title: Transfer learning in a biomaterial fibrosis model identifies in vivo senescence heterogeneity and contributions to vascularization and matrix production across species and diverse pathologies.
Volume: 45
Issue: 4
Pages: 2559-2587
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14665695 | J:87339
First Author: Zindy F
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Arf tumor suppressor promoter monitors latent oncogenic signals in vivo.
Volume: 100
Issue: 26
Pages: 15930-5
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9851971 | J:51558
First Author: Holland EC
Year: 1998
Journal: Genes Dev
Title: Modeling mutations in the G1 arrest pathway in human gliomas: overexpression of CDK4 but not loss of INK4a-ARF induces hyperploidy in cultured mouse astrocytes.
Volume: 12
Issue: 23
Pages: 3644-9
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24386508 | J:204127
First Author: Robinson GL
Year: 2013
Journal: Genes Cancer
Title: Akt signaling accelerates tumor recurrence following ras inhibition in the context of ink4a/arf loss.
Volume: 4
Issue: 11-12
Pages: 476-85
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22696052 | J:191609
First Author: Goukassian DA
Year: 2012
Journal: J Invest Dermatol
Title: Topical application of thymidine dinucleotide to newborn mice reduces and delays development of UV-induced melanomas.
Volume: 132
Issue: 11
Pages: 2664-6
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21216978 | J:171161
First Author: Solodushko V
Year: 2011
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Heterogeneous activation of p19Arf in pulmonary artery smooth muscle cells.
Volume: 300
Issue: 4
Pages: L642-7
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20444198 | J:229152
First Author: VanBrocklin MW
Year: 2010
Journal: Pigment Cell Melanoma Res
Title: Targeted delivery of NRASQ61R and Cre-recombinase to post-natal melanocytes induces melanoma in Ink4a/Arflox/lox mice.
Volume: 23
Issue: 4
Pages: 531-41
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36203755 | J:350532
 
First Author: Kyi P
Year: 2022
Journal: Front Med (Lausanne)
Title: Endothelial senescence mediates hypoxia-induced vascular remodeling by modulating PDGFB expression.
Volume: 9
Pages: 908639
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37019080 | J:346266
First Author: Liu X
Year: 2023
Journal: Cell Metab
Title: Oxylipin-PPARγ-initiated adipocyte senescence propagates secondary senescence in the bone marrow.
Volume: 35
Issue: 4
Pages: 667-684.e6
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34617510 | J:348889
   
First Author: Saul D
Year: 2021
Journal: Elife
Title: Modulation of fracture healing by the transient accumulation of senescent cells.
Volume: 10
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35168063 | J:336594
 
First Author: Shimada-Takayama Y
Year: 2022
Journal: Biochem Biophys Res Commun
Title: Generation of mice for evaluating endogenous p16(Ink4a) protein expression.
Volume: 599
Pages: 43-50
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25077764 | J:235276
First Author: Saito M
Year: 2014
Journal: Exp Anim
Title: Identification of Stmm3 locus conferring resistance to late-stage chemically induced skin papillomas on mouse chromosome 4 by congenic mapping and allele-specific alteration analysis.
Volume: 63
Issue: 3
Pages: 339-48
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30683717 | J:272509
First Author: Liu JY
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Cells exhibiting strong p16 INK4a promoter activation in vivo display features of senescence.
Volume: 116
Issue: 7
Pages: 2603-2611
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Publication
16540653 | J:296094
First Author: Colombo E
Year: 2006
Journal: Cancer Res
Title: Delocalization and destabilization of the Arf tumor suppressor by the leukemia-associated NPM mutant.
Volume: 66
Issue: 6
Pages: 3044-50
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Publication
9878046 | J:51904
First Author: Honda R
Year: 1999
Journal: EMBO J
Title: Association of p19(ARF) with Mdm2 inhibits ubiquitin ligase activity of Mdm2 for tumor suppressor p53.
Volume: 18
Issue: 1
Pages: 22-7
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11407943 | J:70652
First Author: Reilly KM
Year: 2001
Journal: Semin Cancer Biol
Title: Genetically engineered mouse models of astrocytoma: GEMs in the rough?
Volume: 11
Issue: 3
Pages: 177-91
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11809177 | J:73725
First Author: Walker GJ
Year: 2002
Journal: Lancet
Title: p16INK4A and p14ARF tumour suppressors in melanoma: lessons from the mouse.
Volume: 359
Issue: 9300
Pages: 7-8
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Publication
11839561 | J:74502
First Author: Hiroyasu M
Year: 2002
Journal: Am J Pathol
Title: Specific allelic loss of p16 (INK4A) tumor suppressor gene after weeks of iron-mediated oxidative damage during rat renal carcinogenesis.
Volume: 160
Issue: 2
Pages: 419-24
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Publication
11859122 | J:74771
First Author: Lagresle C
Year: 2002
Journal: J Immunol
Title: Transgenic expression of the p16(INK4a) cyclin-dependent kinase inhibitor leads to enhanced apoptosis and differentiation arrest of CD4-CD8- immature thymocytes.
Volume: 168
Issue: 5
Pages: 2325-31
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Publication
10783305 | J:62199
First Author: Serrano M
Year: 2000
Journal: Carcinogenesis
Title: The INK4a/ARF locus in murine tumorigenesis.
Volume: 21
Issue: 5
Pages: 865-9
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10964101 | J:64371
First Author: Patel AC
Year: 2000
Journal: Carcinogenesis
Title: Hypermethylation of the p16 (Ink4a) promoter in B6C3F1 mouse primary lung adenocarcinomas and mouse lung cell lines.
Volume: 21
Issue: 9
Pages: 1691-700
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7987387 | J:42681
First Author: Hussussian CJ
Year: 1994
Journal: Nat Genet
Title: Germline p16 mutations in familial melanoma.
Volume: 8
Issue: 1
Pages: 15-21
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Publication
8924897 | J:32995
First Author: Miyasaka K
Year: 1996
Journal: Biol Pharm Bull
Title: Homozygous deletion of mouse homolog of p16/CDKN2 gene on chromosome 4 in mouse liver epithelial cells in culture.
Volume: 19
Issue: 3
Pages: 345-9
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Publication
8741575 | J:33998
First Author: Miyasaka K
Year: 1996
Journal: Biol Pharm Bull
Title: Allelotype analysis in mouse hepatocellular carcinomas; frequent homozygous deletion of mouse homolog of p16/CDKN2 gene on chromosome 4 in culture.
Volume: 19
Issue: 5
Pages: 683-91
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Publication
9032263 | J:38517
First Author: Swafford DS
Year: 1997
Journal: Mol Cell Biol
Title: Frequent aberrant methylation of p16INK4a in primary rat lung tumors.
Volume: 17
Issue: 3
Pages: 1366-74
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Publication
9054597 | J:38603
First Author: Belinsky SA
Year: 1997
Journal: Carcinogenesis
Title: Deletion and differential expression of p16INK4a in mouse lung tumors.
Volume: 18
Issue: 1
Pages: 115-20
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