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Search results 301 to 367 out of 367 for Irs1

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Category: Publication
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Type Details Score
Publication
22326951 | J:184484
First Author: Battiprolu PK
Year: 2012
Journal: J Clin Invest
Title: Metabolic stress-induced activation of FoxO1 triggers diabetic cardiomyopathy in mice.
Volume: 122
Issue: 3
Pages: 1109-18
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Publication
20197085 | J:164141
First Author: Swindell WR
Year: 2010
Journal: Exp Gerontol
Title: In vivo analysis of gene expression in long-lived mice lacking the pregnancy-associated plasma protein A (PappA) gene.
Volume: 45
Issue: 5
Pages: 366-74
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Publication
20967535 | J:166051
First Author: Kuo LH
Year: 2011
Journal: Diabetologia
Title: Toll-like receptor 2 deficiency improves insulin sensitivity and hepatic insulin signalling in the mouse.
Volume: 54
Issue: 1
Pages: 168-79
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Publication
15306821 | J:92663
First Author: Um SH
Year: 2004
Journal: Nature
Title: Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity.
Volume: 431
Issue: 7005
Pages: 200-5
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Publication
12101187 | J:79280
First Author: Kido Y
Year: 2002
Journal: J Biol Chem
Title: Effects of mutations in the insulin-like growth factor signaling system on embryonic pancreas development and beta-cell compensation to insulin resistance.
Volume: 277
Issue: 39
Pages: 36740-7
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Publication
10995442 | J:68751
First Author: Sachs M
Year: 2000
Journal: J Cell Biol
Title: Essential role of Gab1 for signaling by the c-Met receptor in vivo.
Volume: 150
Issue: 6
Pages: 1375-84
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Publication
32101031 | J:296811
First Author: Zhang L
Year: 2020
Journal: Am J Physiol Endocrinol Metab
Title: Stat3 activation induces insulin resistance via a muscle-specific E3 ubiquitin ligase Fbxo40.
Volume: 318
Issue: 5
Pages: E625-E635
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Publication
24397921 | J:211950
First Author: Poursharifi P
Year: 2014
Journal: Mol Cell Endocrinol
Title: C5aR and C5L2 act in concert to balance immunometabolism in adipose tissue.
Volume: 382
Issue: 1
Pages: 325-33
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Publication
30031227 | J:348501
First Author: Tramutola A
Year: 2018
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Proteomic identification of altered protein O-GlcNAcylation in a triple transgenic mouse model of Alzheimer's disease.
Volume: 1864
Issue: 10
Pages: 3309-3321
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Publication
24435134 | J:210098
 
First Author: Ong QR
Year: 2014
Journal: Sci Rep
Title: Reduced phosphorylation of brain insulin receptor substrate and Akt proteins in apolipoprotein-E4 targeted replacement mice.
Volume: 4
Pages: 3754
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Publication
20841350 | J:167406
First Author: Matsuo K
Year: 2010
Journal: J Biol Chem
Title: Altered glucose homeostasis in mice with liver-specific deletion of Src homology phosphatase 2.
Volume: 285
Issue: 51
Pages: 39750-8
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Publication
20407209 | J:161466
First Author: Shimizu I
Year: 2010
Journal: J Clin Invest
Title: Excessive cardiac insulin signaling exacerbates systolic dysfunction induced by pressure overload in rodents.
Volume: 120
Issue: 5
Pages: 1506-14
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Publication
22418434 | J:185463
First Author: Inazuka F
Year: 2012
Journal: J Biol Chem
Title: Muscle-specific knock-out of NUAK family SNF1-like kinase 1 (NUAK1) prevents high fat diet-induced glucose intolerance.
Volume: 287
Issue: 20
Pages: 16379-89
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Publication
29795582 | J:262390
First Author: Taga M
Year: 2018
Journal: PLoS One
Title: PKR modulates abnormal brain signaling in experimental obesity.
Volume: 13
Issue: 5
Pages: e0196983
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Publication
24379345 | J:229139
First Author: Wu S
Year: 2014
Journal: Diabetes
Title: Obesity-induced infertility and hyperandrogenism are corrected by deletion of the insulin receptor in the ovarian theca cell.
Volume: 63
Issue: 4
Pages: 1270-82
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Publication
22076926 | J:191388
First Author: Wu S
Year: 2012
Journal: Diabetes
Title: Reproductive tissues maintain insulin sensitivity in diet-induced obesity.
Volume: 61
Issue: 1
Pages: 114-23
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Publication
23396401 | J:208551
First Author: Zhang W
Year: 2013
Journal: Diabetes
Title: Liver kinase b1 is required for white adipose tissue growth and differentiation.
Volume: 62
Issue: 7
Pages: 2347-58
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Publication
31336149 | J:280511
First Author: Hörbelt T
Year: 2019
Journal: Biochim Biophys Acta Mol Basis Dis
Title: The adipokine sFRP4 induces insulin resistance and lipogenesis in the liver.
Volume: 1865
Issue: 10
Pages: 2671-2684
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Publication
15314154 | J:92794
First Author: Duan C
Year: 2004
Journal: Mol Cell Biol
Title: Disruption of the SH2-B gene causes age-dependent insulin resistance and glucose intolerance.
Volume: 24
Issue: 17
Pages: 7435-43
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Publication
33297755 | J:318576
First Author: Sun J
Year: 2021
Journal: Arterioscler Thromb Vasc Biol
Title: Endothelial TFEB (Transcription Factor EB) Improves Glucose Tolerance via Upregulation of IRS (Insulin Receptor Substrate) 1 and IRS2.
Volume: 41
Issue: 2
Pages: 783-795
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Publication
19723629 | J:155840
First Author: Kienesberger PC
Year: 2009
Journal: J Biol Chem
Title: Adipose triglyceride lipase deficiency causes tissue-specific changes in insulin signaling.
Volume: 284
Issue: 44
Pages: 30218-29
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Publication
26801556 | J:233337
First Author: Jeong HW
Year: 2016
Journal: Biochem Biophys Res Commun
Title: Tribbles 3 inhibits brown adipocyte differentiation and function by suppressing insulin signaling.
Volume: 470
Issue: 4
Pages: 783-91
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Publication
29386390 | J:258290
First Author: Wardhana DA
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Family with sequence similarity 13, member A modulates adipocyte insulin signaling and preserves systemic metabolic homeostasis.
Volume: 115
Issue: 7
Pages: 1529-1534
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Publication
24265765 | J:338241
First Author: Myers SA
Year: 2013
Journal: PLoS One
Title: The zinc transporter, Slc39a7 (Zip7) is implicated in glycaemic control in skeletal muscle cells.
Volume: 8
Issue: 11
Pages: e79316
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Publication
15572028 | J:161023
First Author: Mohanty S
Year: 2005
Journal: Exp Cell Res
Title: Overexpression of IRS2 in isolated pancreatic islets causes proliferation and protects human beta-cells from hyperglycemia-induced apoptosis.
Volume: 303
Issue: 1
Pages: 68-78
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Publication
10422536 | J:159275
First Author: Cui X
Year: 1999
Journal: Mutat Res
Title: The XRCC2 and XRCC3 repair genes are required for chromosome stability in mammalian cells.
Volume: 434
Issue: 2
Pages: 75-88
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Publication
15699039 | J:98748
First Author: Wharton J
Year: 2005
Journal: J Biol Chem
Title: Dissociation of insulin receptor expression and signaling from caveolin-1 expression.
Volume: 280
Issue: 14
Pages: 13483-6
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Publication
16505233 | J:106855
First Author: Shi H
Year: 2006
Journal: Diabetes
Title: Overexpression of suppressor of cytokine signaling 3 in adipose tissue causes local but not systemic insulin resistance.
Volume: 55
Issue: 3
Pages: 699-707
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Publication
16916938 | J:115991
First Author: Guo S
Year: 2006
Journal: Mol Endocrinol
Title: The reciprocal stability of FOXO1 and IRS2 creates a regulatory circuit that controls insulin signaling.
Volume: 20
Issue: 12
Pages: 3389-99
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Publication
19675138 | J:154382
First Author: Morgan SA
Year: 2009
Journal: Diabetes
Title: 11beta-hydroxysteroid dehydrogenase type 1 regulates glucocorticoid-induced insulin resistance in skeletal muscle.
Volume: 58
Issue: 11
Pages: 2506-15
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Publication
21305007 | J:169542
First Author: Matsuo K
Year: 2011
Journal: PLoS One
Title: Regulation of brown fat adipogenesis by protein tyrosine phosphatase 1B.
Volume: 6
Issue: 1
Pages: e16446
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Publication
23201159 | J:198859
First Author: Yin Y
Year: 2013
Journal: Biochim Biophys Acta
Title: Downregulation of miR-145 associated with cancer progression and VEGF transcriptional activation by targeting N-RAS and IRS1.
Volume: 1829
Issue: 2
Pages: 239-47
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Publication
28724990 | J:251732
First Author: Zillikens MC
Year: 2017
Journal: Nat Commun
Title: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.
Volume: 8
Issue: 1
Pages: 80
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Publication
28655716 | J:259731
First Author: Ohlsson C
Year: 2017
Journal: Am J Physiol Endocrinol Metab
Title: Increased adipose tissue aromatase activity improves insulin sensitivity and reduces adipose tissue inflammation in male mice.
Volume: 313
Issue: 4
Pages: E450-E462
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Publication
29440699 | J:263023
First Author: Nguyen Dinh Cat A
Year: 2018
Journal: Sci Rep
Title: Vascular dysfunction in obese diabetic db/db mice involves the interplay between aldosterone/mineralocorticoid receptor and Rho kinase signaling.
Volume: 8
Issue: 1
Pages: 2952
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Publication
30509997 | J:268948
First Author: Andersson KME
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Inflammation in the hippocampus affects IGF1 receptor signaling and contributes to neurological sequelae in rheumatoid arthritis.
Volume: 115
Issue: 51
Pages: E12063-E12072
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Publication
29685905 | J:265277
 
First Author: Mercado-Matos J
Year: 2018
Journal: Mol Cell Biol
Title: Identification of a Novel Invasion-Promoting Region in Insulin Receptor Substrate 2.
Volume: 38
Issue: 14
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Publication
27200419 | J:283266
 
First Author: Park K
Year: 2016
Journal: JCI Insight
Title: Insulin decreases atherosclerosis by inducing endothelin receptor B expression.
Volume: 1
Issue: 6
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Publication
33408127 | J:306294
First Author: Liao W
Year: 2021
Journal: Diabetes
Title: Heme Oxygenase-1 Regulates Ferrous Iron and Foxo1 in Control of Hepatic Gluconeogenesis.
Volume: 70
Issue: 3
Pages: 696-709
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Publication
27765041 | J:316548
First Author: Farabaugh SM
Year: 2016
Journal: Cell Commun Signal
Title: Lack of interaction between ErbB2 and insulin receptor substrate signaling in breast cancer.
Volume: 14
Issue: 1
Pages: 25
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Publication
32531054 | J:356106
First Author: Nolte MJ
Year: 2020
Journal: Genome Biol Evol
Title: Giant Island Mice Exhibit Widespread Gene Expression Changes in Key Metabolic Organs.
Volume: 12
Issue: 8
Pages: 1277-1301
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Publication
12138094 | -
First Author: Pandini G
Year: 2002
Journal: J Biol Chem
Title: Insulin/insulin-like growth factor I hybrid receptors have different biological characteristics depending on the insulin receptor isoform involved.
Volume: 277
Issue: 42
Pages: 39684-95
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Publication
16831875 | -
First Author: Slaaby R
Year: 2006
Journal: J Biol Chem
Title: Hybrid receptors formed by insulin receptor (IR) and insulin-like growth factor I receptor (IGF-IR) have low insulin and high IGF-1 affinity irrespective of the IR splice variant.
Volume: 281
Issue: 36
Pages: 25869-74
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Publication
8276809 | -
First Author: Van Horn DJ
Year: 1994
Journal: J Biol Chem
Title: Direct activation of the phosphatidylinositol 3'-kinase by the insulin receptor.
Volume: 269
Issue: 1
Pages: 29-32
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Publication
14516276 | J:159073
First Author: Kimber WA
Year: 2003
Journal: Biochem J
Title: Interaction of the protein tyrosine phosphatase PTPL1 with the PtdIns(3,4)P2-binding adaptor protein TAPP1.
Volume: 376
Issue: Pt 2
Pages: 525-35
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Publication
23056509 | J:192101
First Author: Munkonda MN
Year: 2012
Journal: PLoS One
Title: Recombinant acylation stimulating protein administration to C3-/- mice increases insulin resistance via adipocyte inflammatory mechanisms.
Volume: 7
Issue: 10
Pages: e46883
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Publication
25361392 | J:218271
First Author: Alvarez-Perez JC
Year: 2014
Journal: Mol Endocrinol
Title: Hepatocyte growth factor ameliorates hyperglycemia and corrects β-cell mass in IRS2-deficient mice.
Volume: 28
Issue: 12
Pages: 2038-48
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Publication
20821187 | J:164577
First Author: Liu Y
Year: 2010
Journal: Diabetologia
Title: Conditional ablation of Gsk-3β in islet beta cells results in expanded mass and resistance to fat feeding-induced diabetes in mice.
Volume: 53
Issue: 12
Pages: 2600-10
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Publication
11113183 | J:67575
First Author: Dufresne SD
Year: 2001
Journal: Mol Cell Biol
Title: Altered extracellular signal-regulated kinase signaling and glycogen metabolism in skeletal muscle from p90 ribosomal S6 kinase 2 knockout mice.
Volume: 21
Issue: 1
Pages: 81-7
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Publication
25099774 | J:310290
First Author: Schneider A
Year: 2014
Journal: Age (Dordr)
Title: Effect of growth hormone receptor gene disruption and PMA treatment on the expression of genes involved in primordial follicle activation in mice ovaries.
Volume: 36
Issue: 4
Pages: 9701
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Publication
33516914 | J:322056
 
First Author: Lanzillotta C
Year: 2021
Journal: Free Radic Biol Med
Title: Insulin resistance, oxidative stress and mitochondrial defects in Ts65dn mice brain: A harmful synergistic path in down syndrome.
Volume: 165
Pages: 152-170
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Publication
24887203 | J:217927
First Author: Pedrós I
Year: 2014
Journal: Biochim Biophys Acta
Title: Early alterations in energy metabolism in the hippocampus of APPswe/PS1dE9 mouse model of Alzheimer's disease.
Volume: 1842
Issue: 9
Pages: 1556-66
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Publication
23056418 | J:192102
First Author: Al-Dwairi A
Year: 2012
Journal: PLoS One
Title: Cytosolic malic enzyme 1 (ME1) mediates high fat diet-induced adiposity, endocrine profile, and gastrointestinal tract proliferation-associated biomarkers in male mice.
Volume: 7
Issue: 10
Pages: e46716
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Publication
28870245 | J:310256
First Author: Consitt LA
Year: 2017
Journal: Skelet Muscle
Title: Mice overexpressing growth hormone exhibit increased skeletal muscle myostatin and MuRF1 with attenuation of muscle mass.
Volume: 7
Issue: 1
Pages: 17
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Publication
23606743 | J:328153
First Author: Motohashi N
Year: 2013
Journal: J Cell Sci
Title: Regulation of IRS1/Akt insulin signaling by microRNA-128a during myogenesis.
Volume: 126
Issue: Pt 12
Pages: 2678-91
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Publication
30462534 | J:272012
First Author: Wang Y
Year: 2019
Journal: Am J Physiol Cell Physiol
Title: Anxa2 gene silencing attenuates obesity-induced insulin resistance by suppressing the NF-κB signaling pathway.
Volume: 316
Issue: 2
Pages: C223-C234
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Publication
33872860 | J:316885
 
First Author: Altamura S
Year: 2021
Journal: Mol Metab
Title: Iron aggravates hepatic insulin resistance in the absence of inflammation in a novel db/db mouse model with iron overload.
Volume: 51
Pages: 101235
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Publication
9869640 | -
First Author: Kamura T
Year: 1998
Journal: Genes Dev
Title: The Elongin BC complex interacts with the conserved SOCS-box motif present in members of the SOCS, ras, WD-40 repeat, and ankyrin repeat families.
Volume: 12
Issue: 24
Pages: 3872-81
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16675548 | -
First Author: Bullock AN
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Crystal structure of the SOCS2-elongin C-elongin B complex defines a prototypical SOCS box ubiquitin ligase.
Volume: 103
Issue: 20
Pages: 7637-42
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Publication
19275641 | -
First Author: Sharma PS
Year: 2009
Journal: Curr Pharm Des
Title: Receptor tyrosine kinase inhibitors as potent weapons in war against cancers.
Volume: 15
Issue: 7
Pages: 758-76
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Publication
16700535 | -
First Author: Li E
Year: 2006
Journal: Biochemistry
Title: Role of receptor tyrosine kinase transmembrane domains in cell signaling and human pathologies.
Volume: 45
Issue: 20
Pages: 6241-51
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Publication
15845350 | -
First Author: Roskoski R Jr
Year: 2005
Journal: Biochem Biophys Res Commun
Title: Src kinase regulation by phosphorylation and dephosphorylation.
Volume: 331
Issue: 1
Pages: 1-14
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Publication
3291115 | J:31015
First Author: Hanks SK
Year: 1988
Journal: Science
Title: The protein kinase family: conserved features and deduced phylogeny of the catalytic domains.
Volume: 241
Issue: 4861
Pages: 42-52
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Publication
12368087 | -
First Author: Manning G
Year: 2002
Journal: Trends Biochem Sci
Title: Evolution of protein kinase signaling from yeast to man.
Volume: 27
Issue: 10
Pages: 514-20
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Publication
12471243 | -
First Author: Manning G
Year: 2002
Journal: Science
Title: The protein kinase complement of the human genome.
Volume: 298
Issue: 5600
Pages: 1912-34
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Publication
15078142 | -
First Author: Stout TJ
Year: 2004
Journal: Curr Pharm Des
Title: High-throughput structural biology in drug discovery: protein kinases.
Volume: 10
Issue: 10
Pages: 1069-82
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Publication
15320712 | -
First Author: Li B
Year: 2004
Journal: Comb Chem High Throughput Screen
Title: Creating chemical diversity to target protein kinases.
Volume: 7
Issue: 5
Pages: 453-72
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