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Search results 301 to 400 out of 1492 for Lck

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Category: Publication
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Type Details Score
Publication
14610046 | J:289012
First Author: Brdicková N
Year: 2003
Journal: J Exp Med
Title: LIME: a new membrane Raft-associated adaptor protein involved in CD4 and CD8 coreceptor signaling.
Volume: 198
Issue: 10
Pages: 1453-62
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Publication
9647223 | J:110916
First Author: Irie HY
Year: 1998
Journal: J Immunol
Title: The cytoplasmic domain of CD8 beta regulates Lck kinase activation and CD8 T cell development.
Volume: 161
Issue: 1
Pages: 183-91
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Publication
38225265 | J:351183
First Author: Shih YC
Year: 2024
Journal: Nat Commun
Title: The phosphatase DUSP22 inhibits UBR2-mediated K63-ubiquitination and activation of Lck downstream of TCR signalling.
Volume: 15
Issue: 1
Pages: 532
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Publication
23931554 | J:200992
First Author: Ventimiglia LN
Year: 2013
Journal: Biochem J
Title: The role of membrane rafts in Lck transport, regulation and signalling in T-cells.
Volume: 454
Issue: 2
Pages: 169-79
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Publication
9670936 | J:48581
First Author: Takemoto Y
Year: 1998
Journal: J Immunol
Title: Growth factor receptor-bound protein 2 (Grb2) association with hemopoietic specific protein 1: linkage between Lck and Grb2.
Volume: 161
Issue: 2
Pages: 625-30
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Publication
16446380 | J:118955
First Author: Marti F
Year: 2006
Journal: J Exp Med
Title: Essential role of the T cell-specific adapter protein in the activation of LCK in peripheral T cells.
Volume: 203
Issue: 2
Pages: 281-7
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Publication
17277109 | J:143998
First Author: Falahati R
Year: 2007
Journal: J Immunol
Title: Changes in the role of the CD45 protein tyrosine phosphatase in regulating Lck tyrosine phosphorylation during thymic development.
Volume: 178
Issue: 4
Pages: 2056-64
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Publication
35860252 | J:330231
 
First Author: Damen H
Year: 2022
Journal: Front Immunol
Title: Negative Regulation of Zap70 by Lck Forms the Mechanistic Basis of Differential Expression in CD4 and CD8 T Cells.
Volume: 13
Pages: 935367
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Publication
- | J:171186
     
First Author: Petrie H
Year: 2011
Journal: MGI Direct Data Submission
Title: A new transgenic mouse expressing Lyl1 (lymphoblastic leukemia 1) under the control of an Lck promoter
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Publication
7736574 | J:24973
First Author: Miyazaki T
Year: 1995
Journal: Cell
Title: Three distinct IL-2 signaling pathways mediated by bcl-2, c-myc, and lck cooperate in hematopoietic cell proliferation.
Volume: 81
Issue: 2
Pages: 223-31
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Publication
35365636 | J:323939
First Author: Jacobsen AV
Year: 2022
Journal: Cell Death Dis
Title: The Lck inhibitor, AMG-47a, blocks necroptosis and implicates RIPK1 in signalling downstream of MLKL.
Volume: 13
Issue: 4
Pages: 291
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Publication
21915273 | J:177766
First Author: Lindquist S
Year: 2011
Journal: PLoS One
Title: Phosphoprotein associated with glycosphingolipid-enriched microdomains differentially modulates SRC kinase activity in brain maturation.
Volume: 6
Issue: 9
Pages: e23978
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Publication
17719247 | J:125225
First Author: McNeill L
Year: 2007
Journal: Immunity
Title: The differential regulation of Lck kinase phosphorylation sites by CD45 is critical for T cell receptor signaling responses.
Volume: 27
Issue: 3
Pages: 425-37
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Publication
30425092 | J:353128
First Author: Suryadevara CM
Year: 2019
Journal: Clin Cancer Res
Title: Preventing Lck Activation in CAR T Cells Confers Treg Resistance but Requires 4-1BB Signaling for Them to Persist and Treat Solid Tumors in Nonlymphodepleted Hosts.
Volume: 25
Issue: 1
Pages: 358-368
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Publication
11133839 | J:336981
First Author: Shimizu C
Year: 2001
Journal: Int Immunol
Title: Progression of T cell lineage restriction in the earliest subpopulation of murine adult thymus visualized by the expression of lck proximal promoter activity.
Volume: 13
Issue: 1
Pages: 105-17
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Publication
9208843 | J:111526
First Author: Fehling HJ
Year: 1997
Journal: Immunity
Title: Restoration of thymopoiesis in pT alpha-/- mice by anti-CD3epsilon antibody treatment or with transgenes encoding activated Lck or tailless pT alpha.
Volume: 6
Issue: 6
Pages: 703-14
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Publication
8413237 | -
First Author: Shenoy-Scaria AM
Year: 1993
Journal: Mol Cell Biol
Title: Palmitylation of an amino-terminal cysteine motif of protein tyrosine kinases p56lck and p59fyn mediates interaction with glycosyl-phosphatidylinositol-anchored proteins.
Volume: 13
Issue: 10
Pages: 6385-92
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Publication
7980442 | -
 
First Author: Koegl M
Year: 1994
Journal: Biochem J
Title: Palmitoylation of multiple Src-family kinases at a homologous N-terminal motif.
Volume: 303 ( Pt 3)
Pages: 749-53
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Publication
17998336 | -
First Author: Li M
Year: 2008
Journal: Mol Cell Biol
Title: The SH3 domain of Lck modulates T-cell receptor-dependent activation of extracellular signal-regulated kinase through activation of Raf-1.
Volume: 28
Issue: 2
Pages: 630-41
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Publication
17918199 | J:126321
First Author: Grégoire C
Year: 2007
Journal: Eur J Immunol
Title: Deletion of the LIME adaptor protein minimally affects T and B cell development and function.
Volume: 37
Issue: 11
Pages: 3259-69
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Publication
31167772 | J:302830
First Author: Fiala GJ
Year: 2019
Journal: J Immunol
Title: Proximal Lck Promoter-Driven Cre Function Is Limited in Neonatal and Ineffective in Adult γδ T Cell Development.
Volume: 203
Issue: 2
Pages: 569-579
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Publication
15489916 | -
First Author: Palacios EH
Year: 2004
Journal: Oncogene
Title: Function of the Src-family kinases, Lck and Fyn, in T-cell development and activation.
Volume: 23
Issue: 48
Pages: 7990-8000
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Publication
11389730 | -
First Author: Giglione C
Year: 2001
Journal: Eur J Biochem
Title: Differential actions of p60c-Src and Lck kinases on the Ras regulators p120-GAP and GDP/GTP exchange factor CDC25Mm.
Volume: 268
Issue: 11
Pages: 3275-83
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Publication
10636863 | -
First Author: Cho YS
Year: 2000
Journal: J Biol Chem
Title: Direct interaction of the CD38 cytoplasmic tail and the Lck SH2 domain. Cd38 transduces T cell activation signals through associated Lck.
Volume: 275
Issue: 3
Pages: 1685-90
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Publication
20074548 | -
First Author: Baumgart F
Year: 2010
Journal: Biochim Biophys Acta
Title: Palmitoylation of R-Ras by human DHHC19, a palmitoyl transferase with a CaaX box.
Volume: 1798
Issue: 3
Pages: 592-604
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Publication
17436253 | -
First Author: Raymond FL
Year: 2007
Journal: Am J Hum Genet
Title: Mutations in ZDHHC9, which encodes a palmitoyltransferase of NRAS and HRAS, cause X-linked mental retardation associated with a Marfanoid habitus.
Volume: 80
Issue: 5
Pages: 982-7
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Publication
9442882 | -
 
First Author: Thomas SM
Year: 1997
Journal: Annu Rev Cell Dev Biol
Title: Cellular functions regulated by Src family kinases.
Volume: 13
Pages: 513-609
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Publication
23166773 | J:195461
First Author: Collins S
Year: 2012
Journal: PLoS One
Title: Regulation of CD4⁺ and CD8⁺ effector responses by Sprouty-1.
Volume: 7
Issue: 11
Pages: e49801
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Publication
17118402 | -
First Author: Romir J
Year: 2007
Journal: J Mol Biol
Title: Crystal structure analysis and solution studies of human Lck-SH3; zinc-induced homodimerization competes with the binding of proline-rich motifs.
Volume: 365
Issue: 5
Pages: 1417-28
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Publication
16249387 | J:129312
First Author: Ahn E
Year: 2006
Journal: Blood
Title: LIME acts as a transmembrane adapter mediating BCR-dependent B-cell activation.
Volume: 107
Issue: 4
Pages: 1521-7
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Publication
17406863 | J:121425
First Author: Huang F
Year: 2007
Journal: Immunogenetics
Title: TM1 and TM2: two mutant alleles that constitute a genetic trait controlling thymocyte development.
Volume: 59
Issue: 6
Pages: 473-7
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Publication
9087424 | J:39450
First Author: Ceci JD
Year: 1997
Journal: Genes Dev
Title: Tpl-2 is an oncogenic kinase that is activated by carboxy-terminal truncation.
Volume: 11
Issue: 6
Pages: 688-700
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8265598 | J:107359
First Author: Lewis DB
Year: 1993
Journal: Proc Natl Acad Sci U S A
Title: Osteoporosis induced in mice by overproduction of interleukin 4.
Volume: 90
Issue: 24
Pages: 11618-22
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20939892 | J:164872
First Author: Chung SH
Year: 2010
Journal: Arthritis Res Ther
Title: CXC chemokine receptor 4 expressed in T cells plays an important role in the development of collagen-induced arthritis.
Volume: 12
Issue: 5
Pages: R188
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8890164 | J:169817
First Author: Cloutier JF
Year: 1996
Journal: EMBO J
Title: Association of inhibitory tyrosine protein kinase p50csk with protein tyrosine phosphatase PEP in T cells and other hemopoietic cells.
Volume: 15
Issue: 18
Pages: 4909-18
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15273934 | -
First Author: Kyogoku C
Year: 2004
Journal: Am J Hum Genet
Title: Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE.
Volume: 75
Issue: 3
Pages: 504-7
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16839418 | -
 
First Author: Granum S
Year: 2006
Journal: BMC Immunol
Title: Structure function analysis of SH2D2A isoforms expressed in T cells reveals a crucial role for the proline rich region encoded by SH2D2A exon 7.
Volume: 7
Pages: 15
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11850626 | J:74993
First Author: Wilkinson B
Year: 2002
Journal: Nat Immunol
Title: TOX: an HMG box protein implicated in the regulation of thymocyte selection.
Volume: 3
Issue: 3
Pages: 272-80
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Publication
15078895 | J:91035
First Author: Aliahmad P
Year: 2004
Journal: J Exp Med
Title: TOX provides a link between calcineurin activation and CD8 lineage commitment.
Volume: 199
Issue: 8
Pages: 1089-99
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1495975 | J:75414
First Author: Orban PC
Year: 1992
Journal: Proc Natl Acad Sci U S A
Title: Tissue- and site-specific DNA recombination in transgenic mice.
Volume: 89
Issue: 15
Pages: 6861-5
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35536646 | J:326847
 
First Author: Canté-Barrett K
Year: 2022
Journal: JCI Insight
Title: MEF2C opposes Notch in lymphoid lineage decision and drives leukemia in the thymus.
Volume: 7
Issue: 13
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21469121 | J:176485
First Author: Mele DA
Year: 2011
Journal: Eur J Immunol
Title: Th17 differentiation is the default program for DPP2-deficient T-cell differentiation.
Volume: 41
Issue: 6
Pages: 1583-93
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18611169 | J:137580
First Author: Servert P
Year: 2008
Journal: Biotechniques
Title: In vivo site-specific recombination using the beta-rec/six system.
Volume: 45
Issue: 1
Pages: 69-78
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Publication
15314041 | J:93656
First Author: Takamori M
Year: 2004
Journal: Int Immunol
Title: BAZF is required for activation of naive CD4 T cells by TCR triggering.
Volume: 16
Issue: 10
Pages: 1439-49
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Publication
16550188 | J:129531
First Author: Hasegawa H
Year: 2006
Journal: Nat Med
Title: Thymus-derived leukemia-lymphoma in mice transgenic for the Tax gene of human T-lymphotropic virus type I.
Volume: 12
Issue: 4
Pages: 466-72
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Publication
20206686 | -
First Author: Bradshaw JM
Year: 2010
Journal: Cell Signal
Title: The Src, Syk, and Tec family kinases: distinct types of molecular switches.
Volume: 22
Issue: 8
Pages: 1175-84
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11466625 | J:154583
First Author: Mende I
Year: 2001
Journal: Oncogene
Title: Oncogenic transformation induced by membrane-targeted Akt2 and Akt3.
Volume: 20
Issue: 32
Pages: 4419-23
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Publication
19414744 | J:150299
First Author: Saeki K
Year: 2009
Journal: J Immunol
Title: A major lipid raft protein raftlin modulates T cell receptor signaling and enhances th17-mediated autoimmune responses.
Volume: 182
Issue: 10
Pages: 5929-37
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10792495 | J:61801
First Author: Aono A
Year: 2000
Journal: Immunology
Title: Forced expression of terminal deoxynucleotidyl transferase in fetal thymus resulted in a decrease in gammadelta T cells and random dissemination of Vgamma3Vdelta1 T cells in skin of newborn but not adult mice.
Volume: 99
Issue: 4
Pages: 489-97
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19395373 | J:149570
First Author: Zhang H
Year: 2009
Journal: Int Immunol
Title: Mammalian nitrilase 1 homologue Nit1 is a negative regulator in T cells.
Volume: 21
Issue: 6
Pages: 691-703
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15499020 | J:93221
First Author: Kong M
Year: 2004
Journal: Science
Title: The PP2A-associated protein alpha4 is an essential inhibitor of apoptosis.
Volume: 306
Issue: 5696
Pages: 695-8
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25585350 | J:219269
First Author: Ahrenhoerster LS
Year: 2015
Journal: Toxicol Appl Pharmacol
Title: Developmental exposure to 2,3,7,8 tetrachlorodibenzo-p-dioxin attenuates later-life Notch1-mediated T cell development and leukemogenesis.
Volume: 283
Issue: 2
Pages: 99-108
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15905513 | J:99008
First Author: Manilay JO
Year: 2005
Journal: J Immunol
Title: Impairment of thymocyte development by dominant-negative Kuzbanian (ADAM-10) is rescued by the Notch ligand, delta-1.
Volume: 174
Issue: 11
Pages: 6732-41
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21642990 | J:176182
First Author: Mavrakis KJ
Year: 2011
Journal: Nat Genet
Title: A cooperative microRNA-tumor suppressor gene network in acute T-cell lymphoblastic leukemia (T-ALL).
Volume: 43
Issue: 7
Pages: 673-8
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12842084 | J:85026
First Author: Beverly LJ
Year: 2003
Journal: Cancer Cell
Title: Perturbation of Ikaros isoform selection by MLV integration is a cooperative event in Notch(IC)-induced T cell leukemogenesis.
Volume: 3
Issue: 6
Pages: 551-64
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19155474 | J:144334
First Author: Bai Z
Year: 2009
Journal: J Immunol
Title: CXC chemokine ligand 12 promotes CCR7-dependent naive T cell trafficking to lymph nodes and Peyer's patches.
Volume: 182
Issue: 3
Pages: 1287-95
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Publication
11359801 | J:69487
First Author: Ohteki T
Year: 2001
Journal: J Immunol
Title: Overexpression of Bcl-2 differentially restores development of thymus-derived CD4-8+ T cells and intestinal intraepithelial T cells in IFN-regulatory factor-1-deficient mice.
Volume: 166
Issue: 11
Pages: 6509-13
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31108170 | J:294439
 
First Author: Rudak PT
Year: 2019
Journal: Brain Behav Immun
Title: Stress-elicited glucocorticoid receptor signaling upregulates TIGIT in innate-like invariant T lymphocytes.
Volume: 80
Pages: 793-804
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17433077 | J:125537
First Author: Stephensen CB
Year: 2007
Journal: Immunology
Title: Disruption of Rxra gene in thymocytes and T lymphocytes modestly alters lymphocyte frequencies, proliferation, survival and T helper type 1/type 2 balance.
Volume: 121
Issue: 4
Pages: 484-98
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25677619 | J:220491
First Author: Kosaka A
Year: 2015
Journal: Biochem Biophys Res Commun
Title: Transgene-derived overexpression of miR-17-92 in CD8+ T-cells confers enhanced cytotoxic activity.
Volume: 458
Issue: 3
Pages: 549-54
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18802005 | J:142743
First Author: Kometani K
Year: 2008
Journal: Blood
Title: Essential role of Rap signal in pre-TCR-mediated beta-selection checkpoint in alphabeta T-cell development.
Volume: 112
Issue: 12
Pages: 4565-73
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29654322 | J:262624
First Author: Murera D
Year: 2018
Journal: Sci Rep
Title: CD4 T cell autophagy is integral to memory maintenance.
Volume: 8
Issue: 1
Pages: 5951
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8062594 | J:20495
First Author: Volpi EV
Year: 1994
Journal: Cytogenet Cell Genet
Title: Subregional mapping of the human lymphocyte-specific protein tyrosine kinase gene (LCK) to 1p35-->p34.3 and its position relative to the 1p marker D1S57.
Volume: 67
Issue: 3
Pages: 187-9
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17878361 | J:152346
First Author: Filby A
Year: 2007
Journal: J Immunol
Title: Fyn regulates the duration of TCR engagement needed for commitment to effector function.
Volume: 179
Issue: 7
Pages: 4635-44
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Publication
20498059 | J:161294
First Author: Jang IK
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Grb2 functions at the top of the T-cell antigen receptor-induced tyrosine kinase cascade to control thymic selection.
Volume: 107
Issue: 23
Pages: 10620-5
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11514606 | J:71098
First Author: Gong Q
Year: 2001
Journal: J Exp Med
Title: Requirement for tyrosine residues 315 and 319 within zeta chain-associated protein 70 for T cell development.
Volume: 194
Issue: 4
Pages: 507-18
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Publication
23209318 | J:190827
First Author: Kortum RL
Year: 2013
Journal: J Immunol
Title: A phospholipase C-γ1-independent, RasGRP1-ERK-dependent pathway drives lymphoproliferative disease in linker for activation of T cells-Y136F mutant mice.
Volume: 190
Issue: 1
Pages: 147-58
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30307073 | J:296496
First Author: Yang JQ
Year: 2019
Journal: Clin Exp Allergy
Title: Rational targeting Cdc42 restrains Th2 cell differentiation and prevents allergic airway inflammation.
Volume: 49
Issue: 1
Pages: 92-107
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23386701 | J:210129
First Author: Gupta A
Year: 2013
Journal: Mutagenesis
Title: T-cell-specific deletion of Mof blocks their differentiation and results in genomic instability in mice.
Volume: 28
Issue: 3
Pages: 263-70
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34171408 | J:312530
 
First Author: Zhong G
Year: 2021
Journal: Neuroscience
Title: The Serum SIRT1 Protein is Associated with the Severity of Injury and Neurological Recovery in Mice with Traumatic Spinal Cord Injury.
Volume: 469
Pages: 103-109
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11781827 | J:73364
First Author: Beneke R
Year: 2001
Journal: Oncogene
Title: Inhibition of poly(ADP-ribose) polymerase activity accelerates T-cell lymphomagenesis in p53 deficient mice.
Volume: 20
Issue: 56
Pages: 8136-41
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26423150 | J:226234
First Author: Rampoldi F
Year: 2015
Journal: J Immunol
Title: Immunosuppression and Aberrant T Cell Development in the Absence of N-Myristoylation.
Volume: 195
Issue: 9
Pages: 4228-43
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21098294 | J:167147
First Author: Zhang N
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Dicer controls CD8+ T-cell activation, migration, and survival.
Volume: 107
Issue: 50
Pages: 21629-34
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Publication
14614856 | J:174583
First Author: Ye M
Year: 2003
Journal: Immunity
Title: Hematopoietic stem cells expressing the myeloid lysozyme gene retain long-term, multilineage repopulation potential.
Volume: 19
Issue: 5
Pages: 689-99
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17905674 | -
First Author: Ingley E
Year: 2008
Journal: Biochim Biophys Acta
Title: Src family kinases: regulation of their activities, levels and identification of new pathways.
Volume: 1784
Issue: 1
Pages: 56-65
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18563293 | -
First Author: Engen JR
Year: 2008
Journal: Cell Mol Life Sci
Title: Structure and dynamic regulation of Src-family kinases.
Volume: 65
Issue: 19
Pages: 3058-73
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11123301 | J:66400
First Author: Porter BO
Year: 2001
Journal: J Immunol
Title: Control of T cell development in vivo by subdomains within the IL-7 receptor alpha-chain cytoplasmic tail.
Volume: 166
Issue: 1
Pages: 262-9
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9794394 | J:50443
First Author: Takeda K
Year: 1998
Journal: J Immunol
Title: Stat3 activation is responsible for IL-6-dependent T cell proliferation through preventing apoptosis: generation and characterization of T cell-specific Stat3-deficient mice.
Volume: 161
Issue: 9
Pages: 4652-60
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18292512 | J:131542
First Author: Owaki T
Year: 2008
Journal: J Immunol
Title: STAT3 is indispensable to IL-27-mediated cell proliferation but not to IL-27-induced Th1 differentiation and suppression of proinflammatory cytokine production.
Volume: 180
Issue: 5
Pages: 2903-11
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25393615 | J:222312
First Author: McIlwain DR
Year: 2015
Journal: Eur J Immunol
Title: T-cell STAT3 is required for the maintenance of humoral immunity to LCMV.
Volume: 45
Issue: 2
Pages: 418-27
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8898201 | J:93005
First Author: Robey E
Year: 1996
Journal: Cell
Title: An activated form of Notch influences the choice between CD4 and CD8 T cell lineages.
Volume: 87
Issue: 3
Pages: 483-92
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17460775 | J:123860
First Author: Cheng Y
Year: 2007
Journal: Neoplasia
Title: Cre-loxP-mediated recombination between the SIL and SCL genes leads to a block in T-cell development at the CD4- CD8- to CD4+ CD8+ transition.
Volume: 9
Issue: 4
Pages: 315-21
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Publication
18487203 | J:138744
First Author: Shrimali RK
Year: 2008
Journal: J Biol Chem
Title: Selenoproteins mediate T cell immunity through an antioxidant mechanism.
Volume: 283
Issue: 29
Pages: 20181-5
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Publication
9692885 | J:67905
First Author: Takahama Y
Year: 1998
Journal: Eur J Immunol
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