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Search results 301 to 400 out of 485 for Lif

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Category: Publication
Type Details Score
Publication
First Author: Kallestad JC
Year: 1991
Journal: J Biol Chem
Title: Disulfide bond assignment and identification of regions required for functional activity of oncostatin M.
Volume: 266
Issue: 14
Pages: 8940-5
Publication
First Author: Derouet D
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Neuropoietin, a new IL-6-related cytokine signaling through the ciliary neurotrophic factor receptor.
Volume: 101
Issue: 14
Pages: 4827-32
Publication
First Author: Hjoberg J
Year: 2004
Journal: J Appl Physiol (1985)
Title: Expression of nitric oxide synthase-2 in the lungs decreases airway resistance and responsiveness.
Volume: 97
Issue: 1
Pages: 249-59
Publication
First Author: Wang Z
Year: 2000
Journal: J Exp Med
Title: Interferon gamma induction of pulmonary emphysema in the adult murine lung.
Volume: 192
Issue: 11
Pages: 1587-600
Publication
First Author: Choo-Wing R
Year: 2013
Journal: Am J Respir Cell Mol Biol
Title: Hyperoxia and interferon-γ-induced injury in developing lungs occur via cyclooxygenase-2 and the endoplasmic reticulum stress-dependent pathway.
Volume: 48
Issue: 6
Pages: 749-57
Publication
First Author: Temann UA
Year: 2002
Journal: J Clin Invest
Title: Pulmonary overexpression of IL-9 induces Th2 cytokine expression, leading to immune pathology.
Volume: 109
Issue: 1
Pages: 29-39
Publication
First Author: Rose TM
Year: 1991
Journal: Proc Natl Acad Sci U S A
Title: Oncostatin M is a member of a cytokine family that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6.
Volume: 88
Issue: 19
Pages: 8641-5
Publication
First Author: Hilton DJ
Year: 1992
Journal: Trends Biochem Sci
Title: LIF: lots of interesting functions.
Volume: 17
Issue: 2
Pages: 72-6
Publication
First Author: Ma B
Year: 2005
Journal: J Clin Invest
Title: Role of CCR5 in IFN-gamma-induced and cigarette smoke-induced emphysema.
Volume: 115
Issue: 12
Pages: 3460-72
Publication
First Author: Harijith A
Year: 2011
Journal: Am J Respir Cell Mol Biol
Title: A role for matrix metalloproteinase 9 in IFNγ-mediated injury in developing lungs: relevance to bronchopulmonary dysplasia.
Volume: 44
Issue: 5
Pages: 621-30
Publication
First Author: Waxman AB
Year: 1998
Journal: J Clin Invest
Title: Targeted lung expression of interleukin-11 enhances murine tolerance of 100% oxygen and diminishes hyperoxia-induced DNA fragmentation.
Volume: 101
Issue: 9
Pages: 1970-82
Publication
First Author: Catela C
Year: 2019
Journal: Neural Dev
Title: An ancient role for collier/Olf/Ebf (COE)-type transcription factors in axial motor neuron development.
Volume: 14
Issue: 1
Pages: 2
Publication
First Author: Azari MF
Year: 2001
Journal: Brain Res
Title: Leukemia inhibitory factor by systemic administration rescues spinal motor neurons in the SOD1 G93A murine model of familial amyotrophic lateral sclerosis.
Volume: 922
Issue: 1
Pages: 144-7
Publication
First Author: Hatta T
Year: 2002
Journal: J Neurosci
Title: The Role of gp130 in cerebral cortical development: in vivo functional analysis in a mouse exo utero system.
Volume: 22
Issue: 13
Pages: 5516-24
Publication
First Author: Giovannini M
Year: 1993
Journal: Cytogenet Cell Genet
Title: Tandem linkage of genes coding for leukemia inhibitory factor (LIF) and oncostatin M (OSM) on human chromosome 22.
Volume: 64
Issue: 3-4
Pages: 240-4
Publication
First Author: Stahl N
Year: 1994
Journal: Science
Title: Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 beta receptor components.
Volume: 263
Issue: 5143
Pages: 92-5
Publication
First Author: Zheng T
Year: 2005
Journal: J Immunol
Title: Role of cathepsin S-dependent epithelial cell apoptosis in IFN-gamma-induced alveolar remodeling and pulmonary emphysema.
Volume: 174
Issue: 12
Pages: 8106-15
Publication  
First Author: Edmond M
Year: 2017
Journal: eNeuro
Title: Topoisomerase IIβ Selectively Regulates Motor Neuron Identity and Peripheral Connectivity through Hox/Pbx-Dependent Transcriptional Programs.
Volume: 4
Issue: 6
Publication
First Author: Lee CG
Year: 2004
Journal: Nat Med
Title: Vascular endothelial growth factor (VEGF) induces remodeling and enhances TH2-mediated sensitization and inflammation in the lung.
Volume: 10
Issue: 10
Pages: 1095-103
Publication
First Author: He CH
Year: 2005
Journal: J Clin Invest
Title: Bcl-2-related protein A1 is an endogenous and cytokine-stimulated mediator of cytoprotection in hyperoxic acute lung injury.
Volume: 115
Issue: 4
Pages: 1039-48
Publication
First Author: Neubauer H
Year: 1998
Journal: Cell
Title: Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis.
Volume: 93
Issue: 3
Pages: 397-409
Publication
First Author: Tartaglia LA
Year: 1995
Journal: Cell
Title: Identification and expression cloning of a leptin receptor, OB-R.
Volume: 83
Issue: 7
Pages: 1263-71
Publication
First Author: Martello G
Year: 2012
Journal: Cell Stem Cell
Title: Esrrb is a pivotal target of the Gsk3/Tcf3 axis regulating embryonic stem cell self-renewal.
Volume: 11
Issue: 4
Pages: 491-504
Publication
First Author: Hariri LP
Year: 2006
Journal: Lasers Surg Med
Title: Endoscopic optical coherence tomography and laser-induced fluorescence spectroscopy in a murine colon cancer model.
Volume: 38
Issue: 4
Pages: 305-13
Publication
First Author: Samardzija M
Year: 2006
Journal: FASEB J
Title: Differential role of Jak-STAT signaling in retinal degenerations.
Volume: 20
Issue: 13
Pages: 2411-3
Publication
First Author: Grossberg AJ
Year: 2010
Journal: Endocrinology
Title: Arcuate nucleus proopiomelanocortin neurons mediate the acute anorectic actions of leukemia inhibitory factor via gp130.
Volume: 151
Issue: 2
Pages: 606-16
Publication
First Author: Durbin JE
Year: 1996
Journal: Cell
Title: Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease.
Volume: 84
Issue: 3
Pages: 443-50
Publication
First Author: Kelleher AM
Year: 2018
Journal: Nat Commun
Title: Uterine glands coordinate on-time embryo implantation and impact endometrial decidualization for pregnancy success.
Volume: 9
Issue: 1
Pages: 2435
Publication
First Author: Koide M
Year: 2017
Journal: J Bone Miner Res
Title: Bone Formation Is Coupled to Resorption Via Suppression of Sclerostin Expression by Osteoclasts.
Volume: 32
Issue: 10
Pages: 2074-2086
Publication
First Author: Alonzi T
Year: 2001
Journal: Mol Cell Neurosci
Title: Role of STAT3 and PI 3-kinase/Akt in mediating the survival actions of cytokines on sensory neurons.
Volume: 18
Issue: 3
Pages: 270-82
Publication
First Author: Walker EC
Year: 2008
Journal: J Bone Miner Res
Title: Cardiotrophin-1 is an osteoclast-derived stimulus of bone formation required for normal bone remodeling.
Volume: 23
Issue: 12
Pages: 2025-32
Publication
First Author: Sakimoto S
Year: 2012
Journal: Development
Title: A role for endothelial cells in promoting the maturation of astrocytes through the apelin/APJ system in mice.
Volume: 139
Issue: 7
Pages: 1327-35
Publication
First Author: Marquardt RM
Year: 2021
Journal: FASEB J
Title: Endometrial epithelial ARID1A is critical for uterine gland function in early pregnancy establishment.
Volume: 35
Issue: 2
Pages: e21209
Publication
First Author: Mu W
Year: 2010
Journal: Dev Biol
Title: PDCD2 is essential for inner cell mass development and embryonic stem cell maintenance.
Volume: 347
Issue: 2
Pages: 279-88
Publication
First Author: Yeo JC
Year: 2014
Journal: Cell Stem Cell
Title: Klf2 is an essential factor that sustains ground state pluripotency.
Volume: 14
Issue: 6
Pages: 864-72
Publication
First Author: Li WZ
Year: 2015
Journal: Biochem Biophys Res Commun
Title: Hesx1 enhances pluripotency by working downstream of multiple pluripotency-associated signaling pathways.
Volume: 464
Issue: 3
Pages: 936-42
Publication
First Author: Sutherland GR
Year: 1989
Journal: Leukemia
Title: The gene for human leukemia inhibitory factor (LIF) maps to 22q12.
Volume: 3
Issue: 1
Pages: 9-13
Publication
First Author: Hara T
Year: 1998
Journal: Dev Biol
Title: Distinct roles of oncostatin M and leukemia inhibitory factor in the development of primordial germ cells and sertoli cells in mice.
Volume: 201
Issue: 2
Pages: 144-53
Publication
First Author: Bamber BA
Year: 1994
Journal: Proc Natl Acad Sci U S A
Title: Leukemia inhibitory factor induces neurotransmitter switching in transgenic mice.
Volume: 91
Issue: 17
Pages: 7839-43
Publication
First Author: Scotland KB
Year: 2009
Journal: Dev Dyn
Title: Analysis of Rex1 (zfp42) function in embryonic stem cell differentiation.
Volume: 238
Issue: 8
Pages: 1863-77
Publication
First Author: Morgani SM
Year: 2013
Journal: Cell Rep
Title: Totipotent embryonic stem cells arise in ground-state culture conditions.
Volume: 3
Issue: 6
Pages: 1945-57
Publication
First Author: Zhang J
Year: 2013
Journal: J Biol Chem
Title: BMP induces cochlin expression to facilitate self-renewal and suppress neural differentiation of mouse embryonic stem cells.
Volume: 288
Issue: 12
Pages: 8053-60
Publication  
First Author: Sutherland L
Year: 2018
Journal: J Cell Sci
Title: LIF-dependent survival of embryonic stem cells is regulated by a novel palmitoylated Gab1 signalling protein.
Volume: 131
Issue: 18
Publication
First Author: Skelly DA
Year: 2020
Journal: Cell Stem Cell
Title: Mapping the Effects of Genetic Variation on Chromatin State and Gene Expression Reveals Loci That Control Ground State Pluripotency.
Volume: 27
Issue: 3
Pages: 459-469.e8
Publication
First Author: Li Z
Year: 2012
Journal: Cell Stem Cell
Title: BMP4 Signaling Acts via dual-specificity phosphatase 9 to control ERK activity in mouse embryonic stem cells.
Volume: 10
Issue: 2
Pages: 171-82
Publication
First Author: Wang P
Year: 2024
Journal: Autophagy
Title: The presence of blastocyst within the uteri facilitates lumenal epithelium transformation for implantation via upregulating lysosome proteostasis activity.
Volume: 20
Issue: 1
Pages: 58-75
Publication
First Author: Sferruzzi-Perri AN
Year: 2009
Journal: Biol Reprod
Title: Csf2 null mutation alters placental gene expression and trophoblast glycogen cell and giant cell abundance in mice.
Volume: 81
Issue: 1
Pages: 207-21
Publication
First Author: Lindberg RA
Year: 1998
Journal: Mol Cell Biol
Title: Cloning and characterization of a specific receptor for mouse oncostatin M.
Volume: 18
Issue: 6
Pages: 3357-67
Publication
First Author: Gendron RL
Year: 2000
Journal: Dev Dyn
Title: Tubedown-1, a novel acetyltransferase associated with blood vessel development.
Volume: 218
Issue: 2
Pages: 300-15
Publication
First Author: Vizlin-Hodzic D
Year: 2011
Journal: Cell Reprogram
Title: SAF-A has a role in transcriptional regulation of Oct4 in ES cells through promoter binding.
Volume: 13
Issue: 1
Pages: 13-27
Publication
First Author: Geserick P
Year: 2004
Journal: Int Immunol
Title: Modulation of T cell development and activation by novel members of the Schlafen (slfn) gene family harbouring an RNA helicase-like motif.
Volume: 16
Issue: 10
Pages: 1535-48
Publication
First Author: Naka T
Year: 1997
Journal: Nature
Title: Structure and function of a new STAT-induced STAT inhibitor.
Volume: 387
Issue: 6636
Pages: 924-9
Publication
First Author: Ye S
Year: 2013
Journal: EMBO J
Title: Embryonic stem cell self-renewal pathways converge on the transcription factor Tfcp2l1.
Volume: 32
Issue: 19
Pages: 2548-60
Publication
First Author: Iha M
Year: 2012
Journal: Reproduction
Title: Effect of ectopic expression of homeoprotein EGAM1C on the cell morphology, growth, and differentiation in a mouse embryonic stem cell line, MG1.19 cells.
Volume: 143
Issue: 4
Pages: 477-89
Publication
First Author: Metcalf JA
Year: 2009
Journal: Mol Genet Metab
Title: Mechanism of shortened bones in mucopolysaccharidosis VII.
Volume: 97
Issue: 3
Pages: 202-11
Publication
First Author: Biffi G
Year: 2019
Journal: Cancer Discov
Title: IL1-Induced JAK/STAT Signaling Is Antagonized by TGFβ to Shape CAF Heterogeneity in Pancreatic Ductal Adenocarcinoma.
Volume: 9
Issue: 2
Pages: 282-301
Publication
First Author: Lang JE
Year: 2008
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Effect of obesity on pulmonary inflammation induced by acute ozone exposure: role of interleukin-6.
Volume: 294
Issue: 5
Pages: L1013-20
Publication
First Author: McNally JB
Year: 2006
Journal: Appl Opt
Title: Task-based imaging of colon cancer in the Apc(Min/+) mouse model.
Volume: 45
Issue: 13
Pages: 3049-62
Publication
First Author: Austin L
Year: 2000
Journal: Muscle Nerve
Title: Leukemia inhibitory factor ameliorates muscle fiber degeneration in the mdx mouse.
Volume: 23
Issue: 11
Pages: 1700-5
Publication
First Author: Kurek JB
Year: 1996
Journal: Muscle Nerve
Title: Leukemia inhibitory factor and interleukin-6 are produced by diseased and regenerating skeletal muscle.
Volume: 19
Issue: 10
Pages: 1291-301
Publication  
First Author: Ash J
Year: 2005
Journal: Mol Vis
Title: Transgenic expression of leukemia inhibitory factor (LIF) blocks normal vascular development but not pathological neovascularization in the eye.
Volume: 11
Pages: 298-308
Publication
First Author: Graham DR
Year: 2005
Journal: Invest Ophthalmol Vis Sci
Title: Leukemia inhibitory factor blocks expression of Crx and Nrl transcription factors to inhibit photoreceptor differentiation.
Volume: 46
Issue: 7
Pages: 2601-10
Publication
First Author: Ikeda K
Year: 1996
Journal: Brain Res
Title: Coadministration of interleukin-6 (IL-6) and soluble IL-6 receptor delays progression of wobbler mouse motor neuron disease.
Volume: 726
Issue: 1-2
Pages: 91-7
Publication
First Author: Pacey LK
Year: 2015
Journal: Brain Behav
Title: Persistent astrocyte activation in the fragile X mouse cerebellum.
Volume: 5
Issue: 10
Pages: e00400
Publication
First Author: Fuchs M
Year: 2003
Journal: FASEB J
Title: Role of interleukin-6 for LV remodeling and survival after experimental myocardial infarction.
Volume: 17
Issue: 14
Pages: 2118-20
Publication
First Author: Chucair-Elliott AJ
Year: 2012
Journal: J Biol Chem
Title: Leukemia inhibitory factor coordinates the down-regulation of the visual cycle in the retina and retinal-pigmented epithelium.
Volume: 287
Issue: 29
Pages: 24092-102
Publication
First Author: Sone M
Year: 2013
Journal: FASEB J
Title: LGR4 expressed in uterine epithelium is necessary for uterine gland development and contributes to decidualization in mice.
Volume: 27
Issue: 12
Pages: 4917-28
Publication
First Author: Quinton LJ
Year: 2008
Journal: Am J Respir Cell Mol Biol
Title: Alveolar epithelial STAT3, IL-6 family cytokines, and host defense during Escherichia coli pneumonia.
Volume: 38
Issue: 6
Pages: 699-706
Publication
First Author: Sun X
Year: 2013
Journal: Mol Endocrinol
Title: Uterine deletion of Gp130 or Stat3 shows implantation failure with increased estrogenic responses.
Volume: 27
Issue: 9
Pages: 1492-501
Publication
First Author: Tiffen PG
Year: 2008
Journal: Mol Endocrinol
Title: A dual role for oncostatin M signaling in the differentiation and death of mammary epithelial cells in vivo.
Volume: 22
Issue: 12
Pages: 2677-88
Publication  
First Author: Kay S
Year: 2016
Journal: Mol Immunol
Title: Fertility defects in Surfactant associated protein D knockout female mice: altered ovarian hormone profile.
Volume: 71
Pages: 87-97
Publication
First Author: Deverman BE
Year: 2012
Journal: J Neurosci
Title: Exogenous leukemia inhibitory factor stimulates oligodendrocyte progenitor cell proliferation and enhances hippocampal remyelination.
Volume: 32
Issue: 6
Pages: 2100-9
Publication
First Author: Rhee KD
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: CNTF-mediated protection of photoreceptors requires initial activation of the cytokine receptor gp130 in Müller glial cells.
Volume: 110
Issue: 47
Pages: E4520-9
Publication
First Author: Namiki T
Year: 2023
Journal: Sci Rep
Title: Uterine epithelial Gp130 orchestrates hormone response and epithelial remodeling for successful embryo attachment in mice.
Volume: 13
Issue: 1
Pages: 854
Publication
First Author: Kanazawa H
Year: 2010
Journal: J Clin Invest
Title: Heart failure causes cholinergic transdifferentiation of cardiac sympathetic nerves via gp130-signaling cytokines in rodents.
Volume: 120
Issue: 2
Pages: 408-21
Publication  
First Author: Jia C
Year: 2019
Journal: Exp Neurol
Title: Vitronectin from brain pericytes promotes adult forebrain neurogenesis by stimulating CNTF.
Volume: 312
Pages: 20-32
Publication
First Author: Hewitt SC
Year: 2020
Journal: J Biol Chem
Title: Estrogen receptor α (ERα)-binding super-enhancers drive key mediators that control uterine estrogen responses in mice.
Volume: 295
Issue: 25
Pages: 8387-8400
Publication
First Author: Fukuda S
Year: 2007
Journal: Mol Cell Biol
Title: Potentiation of astrogliogenesis by STAT3-mediated activation of bone morphogenetic protein-Smad signaling in neural stem cells.
Volume: 27
Issue: 13
Pages: 4931-7
Publication
First Author: Dhakal P
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Sexually dimorphic effects of forkhead box a2 (FOXA2) and uterine glands on decidualization and fetoplacental development.
Volume: 117
Issue: 38
Pages: 23952-23959
Publication
First Author: Jeong JW
Year: 2010
Journal: Biol Reprod
Title: Foxa2 is essential for mouse endometrial gland development and fertility.
Volume: 83
Issue: 3
Pages: 396-403
Publication
First Author: Dhakal P
Year: 2021
Journal: FASEB J
Title: Uterine glands impact embryo survival and stromal cell decidualization in mice.
Volume: 35
Issue: 10
Pages: e21938
Publication
First Author: Hong P
Year: 2014
Journal: Glia
Title: Functional requirement of dicer1 and miR-17-5p in reactive astrocyte proliferation after spinal cord injury in the mouse.
Volume: 62
Issue: 12
Pages: 2044-60
Publication
First Author: Brandt N
Year: 2015
Journal: Am J Physiol Endocrinol Metab
Title: Leukemia inhibitory factor increases glucose uptake in mouse skeletal muscle.
Volume: 309
Issue: 2
Pages: E142-53
Publication
First Author: Raz R
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Essential role of STAT3 for embryonic stem cell pluripotency.
Volume: 96
Issue: 6
Pages: 2846-51
Publication
First Author: Hagiwara Y
Year: 2007
Journal: J Mol Cell Cardiol
Title: SHP2-mediated signaling cascade through gp130 is essential for LIF-dependent I CaL, [Ca2+]i transient, and APD increase in cardiomyocytes.
Volume: 43
Issue: 6
Pages: 710-6
Publication
First Author: Ernst M
Year: 2001
Journal: J Exp Med
Title: Defective gp130-mediated signal transducer and activator of transcription (STAT) signaling results in degenerative joint disease, gastrointestinal ulceration, and failure of uterine implantation.
Volume: 194
Issue: 2
Pages: 189-203
Publication  
First Author: Li A
Year: 2016
Journal: BMC Biol
Title: Mesodermal ALK5 controls lung myofibroblast versus lipofibroblast cell fate.
Volume: 14
Pages: 19
Publication
First Author: Gainsford T
Year: 2000
Journal: Blood
Title: The residual megakaryocyte and platelet production in c-mpl-deficient mice is not dependent on the actions of interleukin-6, interleukin-11, or leukemia inhibitory factor.
Volume: 95
Issue: 2
Pages: 528-34
Publication
First Author: Lee SH
Year: 2017
Journal: Reproduction
Title: The critical role of uterine CD31 as a post-progesterone signal in early pregnancy.
Volume: 154
Issue: 5
Pages: 595-605
Publication
First Author: Jia C
Year: 2018
Journal: Glia
Title: Inhibition of astrocyte FAK-JNK signaling promotes subventricular zone neurogenesis through CNTF.
Volume: 66
Issue: 11
Pages: 2456-2469
Publication
First Author: Plowman SJ
Year: 2006
Journal: Exp Cell Res
Title: The K-Ras 4A isoform promotes apoptosis but does not affect either lifespan or spontaneous tumor incidence in aging mice.
Volume: 312
Issue: 1
Pages: 16-26
Publication  
First Author: Roy S
Year: 2022
Journal: Endocrinology
Title: Jumonji Domain-containing Protein-3 (JMJD3/Kdm6b) Is Critical for Normal Ovarian Function and Female Fertility.
Volume: 163
Issue: 5
Publication
First Author: Takaki E
Year: 2006
Journal: J Biol Chem
Title: Maintenance of olfactory neurogenesis requires HSF1, a major heat shock transcription factor in mice.
Volume: 281
Issue: 8
Pages: 4931-7
Publication
First Author: Lu Y
Year: 2006
Journal: J Biol Chem
Title: Loss of SOCS3 gene expression converts STAT3 function from anti-apoptotic to pro-apoptotic.
Volume: 281
Issue: 48
Pages: 36683-90
Publication
First Author: Hooper MJ
Year: 2018
Journal: Sci Rep
Title: Damage-associated molecular pattern recognition is required for induction of retinal neuroprotective pathways in a sex-dependent manner.
Volume: 8
Issue: 1
Pages: 9115
Publication
First Author: Trouillas M
Year: 2008
Journal: Cell Death Differ
Title: Bcl2, a transcriptional target of p38alpha, is critical for neuronal commitment of mouse embryonic stem cells.
Volume: 15
Issue: 9
Pages: 1450-9
Publication
First Author: Todaro F
Year: 2019
Journal: Stem Cells
Title: Regulation of Kit Expression in Early Mouse Embryos and ES Cells.
Volume: 37
Issue: 3
Pages: 332-344
Publication
First Author: Lapp DW
Year: 2014
Journal: Glia
Title: Stat3 mediates LIF-induced protection of astrocytes against toxic ROS by upregulating the UPC2 mRNA pool.
Volume: 62
Issue: 2
Pages: 159-70
Publication
First Author: Sunde J
Year: 2024
Journal: PLoS One
Title: The uterine secretome initiates growth of gynecologic tissues in ectopic locations.
Volume: 19
Issue: 5
Pages: e0292978
Publication
First Author: Mathieu ME
Year: 2013
Journal: Development
Title: MRAS GTPase is a novel stemness marker that impacts mouse embryonic stem cell plasticity and Xenopus embryonic cell fate.
Volume: 140
Issue: 16
Pages: 3311-22