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Search results 301 to 400 out of 2663 for Psen1

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Type Details Score
Publication
29141186 | J:257779
 
First Author: Shapira R
Year: 2018
Journal: Neurobiol Aging
Title: Hyperbaric oxygen therapy ameliorates pathophysiology of 3xTg-AD mouse model by attenuating neuroinflammation.
Volume: 62
Pages: 105-119
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Publication
26876740 | J:230861
 
First Author: Zou J
Year: 2016
Journal: Brain Res
Title: Learning impairment by minimal cortical injury in a mouse model of Alzheimer's disease.
Volume: 1637
Pages: 56-63
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20359775 | J:188247
First Author: Knight EM
Year: 2012
Journal: Neurobiol Aging
Title: Hypermetabolism in a triple-transgenic mouse model of Alzheimer's disease.
Volume: 33
Issue: 1
Pages: 187-93
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Publication
25541422 | J:219588
First Author: Scala F
Year: 2015
Journal: Neurobiol Aging
Title: Intraneuronal Aβ accumulation induces hippocampal neuron hyperexcitability through A-type K(+) current inhibition mediated by activation of caspases and GSK-3.
Volume: 36
Issue: 2
Pages: 886-900
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Publication
33285637 | J:351954
First Author: Stojakovic A
Year: 2021
Journal: J Alzheimers Dis
Title: Partial Inhibition of Mitochondrial Complex I Reduces Tau Pathology and Improves Energy Homeostasis and Synaptic Function in 3xTg-AD Mice.
Volume: 79
Issue: 1
Pages: 335-353
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Publication
34838667 | J:322616
 
First Author: Lin X
Year: 2022
Journal: Neurobiol Dis
Title: Spatial coding defects of hippocampal neural ensemble calcium activities in the triple-transgenic Alzheimer's disease mouse model.
Volume: 162
Pages: 105562
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Publication
31065079 | J:279862
First Author: Li G
Year: 2019
Journal: Sci Rep
Title: High-throughput metabolomics and ingenuity pathway approach reveals the pharmacological effect and targets of Ginsenoside Rg1 in Alzheimer's disease mice.
Volume: 9
Issue: 1
Pages: 7040
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Publication
26162480 | J:285086
 
First Author: Martinez-Coria H
Year: 2015
Journal: Brain Res Bull
Title: Repeated cognitive stimulation alleviates memory impairments in an Alzheimer's disease mouse model.
Volume: 117
Pages: 10-5
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Publication
31813629 | J:298321
 
First Author: Bonfili L
Year: 2020
Journal: Neurobiol Aging
Title: Gut microbiota manipulation through probiotics oral administration restores glucose homeostasis in a mouse model of Alzheimer's disease.
Volume: 87
Pages: 35-43
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Publication
19020010 | J:142370
First Author: Oddo S
Year: 2008
Journal: J Neurosci
Title: Blocking Abeta42 accumulation delays the onset and progression of tau pathology via the C terminus of heat shock protein70-interacting protein: a mechanistic link between Abeta and tau pathology.
Volume: 28
Issue: 47
Pages: 12163-75
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Publication
31130848 | J:284316
 
First Author: Sanguinetti E
Year: 2019
Journal: Front Cell Neurosci
Title: Combined Effect of Fatty Diet and Cognitive Decline on Brain Metabolism, Food Intake, Body Weight, and Counteraction by Intranasal Insulin Therapy in 3×Tg Mice.
Volume: 13
Pages: 188
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Publication
19705573 | J:153528
First Author: Bourasset F
Year: 2009
Journal: Neuropharmacology
Title: Reduction of the cerebrovascular volume in a transgenic mouse model of Alzheimer's disease.
Volume: 56
Issue: 4
Pages: 808-13
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Publication
29847796 | J:270730
First Author: Flamier A
Year: 2018
Journal: Cell Rep
Title: Modeling Late-Onset Sporadic Alzheimer's Disease through BMI1 Deficiency.
Volume: 23
Issue: 9
Pages: 2653-2666
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Publication
29068127 | J:351780
First Author: Lin KH
Year: 2018
Journal: Environ Toxicol
Title: The preventive effects of edible folic acid on cardiomyocyte apoptosis and survival in early onset triple-transgenic Alzheimer's disease model mice.
Volume: 33
Issue: 1
Pages: 83-92
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Publication
29233183 | J:351782
First Author: Hwang KD
Year: 2017
Journal: Mol Brain
Title: Restoring synaptic plasticity and memory in mouse models of Alzheimer's disease by PKR inhibition.
Volume: 10
Issue: 1
Pages: 57
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Publication
29204248 | J:351781
 
First Author: Nie L
Year: 2017
Journal: Oxid Med Cell Longev
Title: Ginsenoside Rg1 Ameliorates Behavioral Abnormalities and Modulates the Hippocampal Proteomic Change in Triple Transgenic Mice of Alzheimer's Disease.
Volume: 2017
Pages: 6473506
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Publication
21423579 | J:171702
First Author: Corona C
Year: 2011
Journal: PLoS One
Title: Effects of dietary supplementation of carnosine on mitochondrial dysfunction, amyloid pathology, and cognitive deficits in 3xTg-AD mice.
Volume: 6
Issue: 3
Pages: e17971
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Publication
32916195 | J:299673
 
First Author: Sarlus H
Year: 2020
Journal: Neuroscience
Title: Chronic Airway Allergy Induces Pro-Inflammatory Responses in the Brain of Wildtype Mice but Not 3xTgAD Mice.
Volume: 448
Pages: 14-27
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28939860 | J:255393
First Author: Chen L
Year: 2017
Journal: Sci Rep
Title: UbasM: An effective balanced optical clearing method for intact biomedical imaging.
Volume: 7
Issue: 1
Pages: 12218
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Publication
37730113 | J:342071
 
First Author: Wang ZJ
Year: 2023
Journal: Neuropharmacology
Title: Semaglutide ameliorates cognition and glucose metabolism dysfunction in the 3xTg mouse model of Alzheimer's disease via the GLP-1R/SIRT1/GLUT4 pathway.
Volume: 240
Pages: 109716
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Publication
22177720 | J:188318
First Author: García-Mesa Y
Year: 2012
Journal: Neurobiol Aging
Title: Melatonin plus physical exercise are highly neuroprotective in the 3xTg-AD mouse.
Volume: 33
Issue: 6
Pages: 1124.e13-29
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Publication
16504943 | J:107582
First Author: Caccamo A
Year: 2006
Journal: Neuron
Title: M1 receptors play a central role in modulating AD-like pathology in transgenic mice.
Volume: 49
Issue: 5
Pages: 671-82
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Publication
23312564 | J:284611
First Author: Baglietto-Vargas D
Year: 2013
Journal: Biol Psychiatry
Title: Mifepristone alters amyloid precursor protein processing to preclude amyloid beta and also reduces tau pathology.
Volume: 74
Issue: 5
Pages: 357-66
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Publication
38400523 | J:350700
First Author: Liu J
Year: 2024
Journal: FEBS J
Title: Icariin ameliorates glycolytic dysfunction in Alzheimer's disease models by activating the Wnt/β-catenin signaling pathway.
Volume: 291
Issue: 10
Pages: 2221-2241
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Publication
30071370 | J:271557
 
First Author: Bourgeois A
Year: 2018
Journal: Neurobiol Aging
Title: Intraneuronal accumulation of C99 contributes to synaptic alterations, apathy-like behavior, and spatial learning deficits in 3×TgAD and 2×TgAD mice.
Volume: 71
Pages: 21-31
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Publication
27173425 | J:249651
First Author: Hayashi-Park E
Year: 2017
Journal: Behav Brain Res
Title: Experimentally induced diabetes worsens neuropathology, but not learning and memory, in middle aged 3xTg mice.
Volume: 322
Issue: Pt B
Pages: 280-287
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Publication
18068923 | J:135291
First Author: Sensi SL
Year: 2008
Journal: Exp Gerontol
Title: Altered oxidant-mediated intraneuronal zinc mobilization in a triple transgenic mouse model of Alzheimer's disease.
Volume: 43
Issue: 5
Pages: 488-92
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Publication
39253611 | J:360716
First Author: Qian K
Year: 2024
Journal: Asian J Pharm Sci
Title: Rational fusion design inspired by cell-penetrating peptide: SS31/S-14 G Humanin hybrid peptide with amplified multimodal efficacy and bio-permeability for the treatment of Alzheimer's disease.
Volume: 19
Issue: 4
Pages: 100938
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Publication
35961538 | J:328004
 
First Author: Castillo-Mariqueo L
Year: 2022
Journal: Behav Brain Res
Title: Clasping, ledge-score coordination and early gait impairments as primary behavioural markers of functional impairment in Alzheimer's disease.
Volume: 435
Pages: 114054
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Publication
20505094 | J:160821
First Author: Clinton LK
Year: 2010
Journal: J Neurosci
Title: Synergistic Interactions between Abeta, tau, and alpha-synuclein: acceleration of neuropathology and cognitive decline.
Volume: 30
Issue: 21
Pages: 7281-9
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Publication
24244584 | J:209696
First Author: Ding F
Year: 2013
Journal: PLoS One
Title: Early decline in glucose transport and metabolism precedes shift to ketogenic system in female aging and Alzheimer's mouse brain: implication for bioenergetic intervention.
Volume: 8
Issue: 11
Pages: e79977
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21951279 | J:178473
First Author: Jung CK
Year: 2011
Journal: J Neurochem
Title: Role of presenilin 1 in structural plasticity of cortical dendritic spines in vivo.
Volume: 119
Issue: 5
Pages: 1064-73
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25680266 | J:221905
First Author: Jensen MM
Year: 2015
Journal: Neurobiol Aging
Title: Prostate stem cell antigen interacts with nicotinic acetylcholine receptors and is affected in Alzheimer's disease.
Volume: 36
Issue: 4
Pages: 1629-1638
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Publication
37619698 | J:339650
 
First Author: Philipsberg PA
Year: 2023
Journal: Neurosci Lett
Title: Chronotate: An open-source tool for manual timestamping and quantification of animal behavior.
Volume: 814
Pages: 137461
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Publication
35153718 | J:321582
 
First Author: Tureckova J
Year: 2021
Journal: Front Aging Neurosci
Title: Compromised Astrocyte Swelling/Volume Regulation in the Hippocampus of the Triple Transgenic Mouse Model of Alzheimer's Disease.
Volume: 13
Pages: 783120
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18687504 | J:161837
First Author: Jo DG
Year: 2010
Journal: Neurobiol Aging
Title: Evidence that gamma-secretase mediates oxidative stress-induced beta-secretase expression in Alzheimer's disease.
Volume: 31
Issue: 6
Pages: 917-25
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Publication
39040060 | J:352150
First Author: Qiao Y
Year: 2024
Journal: iScience
Title: The role of m6A modification in the risk prediction and Notch1 pathway of Alzheimer's disease.
Volume: 27
Issue: 7
Pages: 110235
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Publication
35286012 | J:350790
First Author: Huang CY
Year: 2022
Journal: Environ Toxicol
Title: Edible folic acid and medicinal folinic acid produce cardioprotective effects in late-stage triple-transgenic Alzheimer's disease model mice by suppressing cardiac hypertrophy and fibrosis.
Volume: 37
Issue: 7
Pages: 1740-1749
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Publication
28941799 | J:254181
First Author: Zandl-Lang M
Year: 2018
Journal: Biochim Biophys Acta
Title: Regulatory effects of simvastatin and apoJ on APP processing and amyloid-β clearance in blood-brain barrier endothelial cells.
Volume: 1863
Issue: 1
Pages: 40-60
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24268884 | J:212736
First Author: Shin MK
Year: 2014
Journal: Neurobiol Aging
Title: Neuropep-1 ameliorates learning and memory deficits in an Alzheimer's disease mouse model, increases brain-derived neurotrophic factor expression in the brain, and causes reduction of amyloid beta plaques.
Volume: 35
Issue: 5
Pages: 990-1001
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20332427 | J:185414
First Author: Cheung KH
Year: 2010
Journal: Sci Signal
Title: Gain-of-function enhancement of IP3 receptor modal gating by familial Alzheimer's disease-linked presenilin mutants in human cells and mouse neurons.
Volume: 3
Issue: 114
Pages: ra22
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29760653 | J:324368
 
First Author: Zhang Q
Year: 2018
Journal: Front Mol Neurosci
Title: CK2 Phosphorylating I2PP2A/SET Mediates Tau Pathology and Cognitive Impairment.
Volume: 11
Pages: 146
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Publication
25446812 | J:223867
 
First Author: Stevens LM
Year: 2015
Journal: Behav Brain Res
Title: Reference and working memory deficits in the 3xTg-AD mouse between 2 and 15-months of age: a cross-sectional study.
Volume: 278
Pages: 496-505
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Publication
36009514 | J:350180
 
First Author: Jullienne A
Year: 2022
Journal: Biomedicines
Title: Progressive Vascular Abnormalities in the Aging 3xTg-AD Mouse Model of Alzheimer's Disease.
Volume: 10
Issue: 8
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20042680 | J:156761
First Author: Martinez-Coria H
Year: 2010
Journal: Am J Pathol
Title: Memantine improves cognition and reduces Alzheimer's-like neuropathology in transgenic mice.
Volume: 176
Issue: 2
Pages: 870-80
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Publication
36194703 | J:350182
First Author: Walter KR
Year: 2023
Journal: Am J Drug Alcohol Abuse
Title: Prenatal alcohol exposure causes persistent microglial activation and age- and sex- specific effects on cognition and metabolic outcomes in an Alzheimer's Disease mouse model.
Volume: 49
Issue: 3
Pages: 302-320
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Publication
23618870 | J:211732
First Author: Edrey YH
Year: 2013
Journal: Neurobiol Aging
Title: Amyloid beta and the longest-lived rodent: the naked mole-rat as a model for natural protection from Alzheimer's disease.
Volume: 34
Issue: 10
Pages: 2352-60
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23155407 | J:195586
First Author: Yan XX
Year: 2012
Journal: PLoS One
Title: Chronic temporal lobe epilepsy is associated with enhanced Alzheimer-like neuropathology in 3×Tg-AD mice.
Volume: 7
Issue: 11
Pages: e48782
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23630570 | J:200630
First Author: Wu W
Year: 2013
Journal: PLoS One
Title: Expression of tryptophan 2,3-dioxygenase and production of kynurenine pathway metabolites in triple transgenic mice and human Alzheimer's disease brain.
Volume: 8
Issue: 4
Pages: e59749
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23804095 | J:199637
First Author: Arsenault D
Year: 2013
Journal: J Neurosci
Title: PAK inactivation impairs social recognition in 3xTg-AD Mice without increasing brain deposition of tau and Aβ.
Volume: 33
Issue: 26
Pages: 10729-40
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Publication
39547338 | J:360793
 
First Author: Wang ZJ
Year: 2024
Journal: Neuroscience
Title: Semaglutide promotes the transition of microglia from M1 to M2 type to reduce brain inflammation in APP/PS1/tau mice.
Volume: 563
Pages: 222-234
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15748844 | J:99604
First Author: Billings LM
Year: 2005
Journal: Neuron
Title: Intraneuronal Abeta causes the onset of early Alzheimer's disease-related cognitive deficits in transgenic mice.
Volume: 45
Issue: 5
Pages: 675-88
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28688899 | J:249714
 
First Author: Velazquez R
Year: 2017
Journal: Neurobiol Aging
Title: Central insulin dysregulation and energy dyshomeostasis in two mouse models of Alzheimer's disease.
Volume: 58
Pages: 1-13
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37735133 | J:350206
First Author: Jin Y
Year: 2023
Journal: J Integr Neurosci
Title: Effect of Physical Exercise on Mitochondrial Dysfunction and Purkinje Cell Survival in the Cerebellum of 3xTg-AD Mice.
Volume: 22
Issue: 5
Pages: 117
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23523959 | J:197629
 
First Author: Torres-Lista V
Year: 2013
Journal: Behav Brain Res
Title: Impairment of nesting behaviour in 3xTg-AD mice.
Volume: 247
Pages: 153-7
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17456772 | J:121081
First Author: Caccamo A
Year: 2007
Journal: Am J Pathol
Title: Lithium reduces tau phosphorylation but not A beta or working memory deficits in a transgenic model with both plaques and tangles.
Volume: 170
Issue: 5
Pages: 1669-75
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23284867 | J:195625
First Author: Chakroborty S
Year: 2012
Journal: PLoS One
Title: Stabilizing ER Ca2+ channel function as an early preventative strategy for Alzheimer's disease.
Volume: 7
Issue: 12
Pages: e52056
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39142368 | J:353616
 
First Author: Ye Y
Year: 2024
Journal: Exp Neurol
Title: Alternate-day fasting improves cognitive and brain energy deficits by promoting ketone metabolism in the 3xTg mouse model of Alzheimer's disease.
Volume: 381
Pages: 114920
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36758468 | J:351246
 
First Author: Li YY
Year: 2023
Journal: Neurobiol Aging
Title: Orexin-A aggravates cognitive deficits in 3xTg-AD mice by exacerbating synaptic plasticity impairment and affecting amyloid β metabolism.
Volume: 124
Pages: 71-84
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32903435 | J:351249
 
First Author: Govindarajulu M
Year: 2020
Journal: Front Mol Neurosci
Title: Gut Metabolite TMAO Induces Synaptic Plasticity Deficits by Promoting Endoplasmic Reticulum Stress.
Volume: 13
Pages: 138
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24726470 | J:214857
First Author: Han P
Year: 2014
Journal: Neurobiol Aging
Title: Pituitary adenylate cyclase-activating polypeptide protects against β-amyloid toxicity.
Volume: 35
Issue: 9
Pages: 2064-71
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27986924 | J:239169
First Author: Prieto GA
Year: 2017
Journal: J Neurosci
Title: Pharmacological Rescue of Long-Term Potentiation in Alzheimer Diseased Synapses.
Volume: 37
Issue: 5
Pages: 1197-1212
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18698410 | J:140591
First Author: Rodríguez JJ
Year: 2008
Journal: PLoS One
Title: Impaired adult neurogenesis in the dentate gyrus of a triple transgenic mouse model of Alzheimer's disease.
Volume: 3
Issue: 8
Pages: e2935
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Publication
38128868 | J:350218
 
First Author: He Z
Year: 2024
Journal: Eur J Pharmacol
Title: Comparative proteomic analysis of cerebral cortex revealed neuroprotective mechanism of esculentoside A on Alzheimer's disease.
Volume: 964
Pages: 176226
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29859867 | J:268585
 
First Author: Silva AC
Year: 2018
Journal: Neurobiol Dis
Title: Blockade of adenosine A2A receptors recovers early deficits of memory and plasticity in the triple transgenic mouse model of Alzheimer's disease.
Volume: 117
Pages: 72-81
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Publication
28392767 | J:275595
 
First Author: Kazim SF
Year: 2017
Journal: Front Aging Neurosci
Title: Early-Onset Network Hyperexcitability in Presymptomatic Alzheimer's Disease Transgenic Mice Is Suppressed by Passive Immunization with Anti-Human APP/Aβ Antibody and by mGluR5 Blockade.
Volume: 9
Pages: 71
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23152608 | J:192455
First Author: Lauritzen I
Year: 2012
Journal: J Neurosci
Title: The β-secretase-derived C-terminal fragment of βAPP, C99, but not Aβ, is a key contributor to early intraneuronal lesions in triple-transgenic mouse hippocampus.
Volume: 32
Issue: 46
Pages: 16243-1655a
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36788598 | J:351251
First Author: Brymer KJ
Year: 2023
Journal: Acta Neuropathol Commun
Title: Asymmetric dysregulation of glutamate dynamics across the synaptic cleft in a mouse model of Alzheimer's disease.
Volume: 11
Issue: 1
Pages: 27
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31186449 | J:278668
First Author: Xia Y
Year: 2019
Journal: Sci Rep
Title: Bifunctional Fluorescent/Raman Nanoprobe for the Early Detection of Amyloid.
Volume: 9
Issue: 1
Pages: 8497
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33613267 | J:351250
 
First Author: Varinthra P
Year: 2021
Journal: Front Aging Neurosci
Title: The 4-(Phenylsulfanyl) butan-2-one Improves Impaired Fear Memory Retrieval and Reduces Excessive Inflammatory Response in Triple Transgenic Alzheimer's Disease Mice.
Volume: 13
Pages: 615079
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37463909 | J:351252
First Author: Post LA
Year: 2023
Journal: Sci Rep
Title: Inceptor as a regulator of brain insulin sensitivity.
Volume: 13
Issue: 1
Pages: 11582
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25008180 | J:230142
First Author: Vandal M
Year: 2014
Journal: Diabetes
Title: Insulin reverses the high-fat diet-induced increase in brain Aβ and improves memory in an animal model of Alzheimer disease.
Volume: 63
Issue: 12
Pages: 4291-301
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39637754 | J:361080
 
First Author: Del Rosario Hernandez T
Year: 2024
Journal: Biomed Pharmacother
Title: Combining supervised and unsupervised analyses to quantify behavioral phenotypes and validate therapeutic efficacy in a triple transgenic mouse model of Alzheimer's disease.
Volume: 181
Pages: 117718
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35017199 | J:351258
First Author: Chen C
Year: 2022
Journal: Gut
Title: Gut microbiota regulate Alzheimer's disease pathologies and cognitive disorders via PUFA-associated neuroinflammation.
Volume: 71
Issue: 11
Pages: 2233-2252
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29946252 | J:270896
 
First Author: Kane AE
Year: 2018
Journal: Front Aging Neurosci
Title: Sex Differences in Healthspan Predict Lifespan in the 3xTg-AD Mouse Model of Alzheimer's Disease.
Volume: 10
Pages: 172
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36046496 | J:351254
 
First Author: Frausto DM
Year: 2022
Journal: Front Aging
Title: Impact of alcohol-induced intestinal microbiota dysbiosis in a rodent model of Alzheimer's disease.
Volume: 3
Pages: 916336
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35559229 | J:325647
 
First Author: Barnett A
Year: 2022
Journal: Front Pharmacol
Title: Adolescent Binge Alcohol Enhances Early Alzheimer's Disease Pathology in Adulthood Through Proinflammatory Neuroimmune Activation.
Volume: 13
Pages: 884170
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26385257 | J:244334
 
First Author: Clark JK
Year: 2015
Journal: Neurobiol Learn Mem
Title: Alterations in synaptic plasticity coincide with deficits in spatial working memory in presymptomatic 3xTg-AD mice.
Volume: 125
Pages: 152-162
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36968493 | J:345227
 
First Author: Hu YT
Year: 2023
Journal: Front Neurosci
Title: Sex differences in hippocampal β-amyloid accumulation in the triple-transgenic mouse model of Alzheimer's disease and the potential role of local estrogens.
Volume: 17
Pages: 1117584
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36142737 | J:348098
 
First Author: Várkonyi D
Year: 2022
Journal: Int J Mol Sci
Title: Investigation of Anxiety- and Depressive-like Symptoms in 4- and 8-Month-Old Male Triple Transgenic Mouse Models of Alzheimer's Disease.
Volume: 23
Issue: 18
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29736736 | J:327287
First Author: Sposato V
Year: 2019
Journal: Mol Neurobiol
Title: The Medial Septum Is Insulin Resistant in the AD Presymptomatic Phase: Rescue by Nerve Growth Factor-Driven IRS1 Activation.
Volume: 56
Issue: 1
Pages: 535-552
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35867714 | J:340929
First Author: Akwa Y
Year: 2023
Journal: Autophagy
Title: Stimulation of synaptic activity promotes TFEB-mediated clearance of pathological MAPT/Tau in cellular and mouse models of tauopathies.
Volume: 19
Issue: 2
Pages: 660-677
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28865961 | J:307498
First Author: Sah SK
Year: 2017
Journal: Biochem Biophys Res Commun
Title: Effect of high-fat diet on cognitive impairment in triple-transgenic mice model of Alzheimer's disease.
Volume: 493
Issue: 1
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