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Search results 301 to 400 out of 1487 for Ptch1

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Type Details Score
Publication
24715461 | J:208849
First Author: Lettice LA
Year: 2014
Journal: Development
Title: Development of five digits is controlled by a bipartite long-range cis-regulator.
Volume: 141
Issue: 8
Pages: 1715-25
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Publication
27459053 | J:233597
First Author: Sánchez-Danés A
Year: 2016
Journal: Nature
Title: Defining the clonal dynamics leading to mouse skin tumour initiation.
Volume: 536
Issue: 7616
Pages: 298-303
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Publication
38517960 | J:346387
First Author: Yamada M
Year: 2024
Journal: Sci Adv
Title: Childhood cancer mutagenesis caused by transposase-derived PGBD5.
Volume: 10
Issue: 12
Pages: eadn4649
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Publication
31873117 | J:297831
First Author: Petroni M
Year: 2019
Journal: Sci Rep
Title: SMO-M2 mutation does not support cell-autonomous Hedgehog activity in cerebellar granule cell precursors.
Volume: 9
Issue: 1
Pages: 19623
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Publication
27496710 | J:235130
First Author: Li P
Year: 2016
Journal: Cancer Res
Title: Nestin Mediates Hedgehog Pathway Tumorigenesis.
Volume: 76
Issue: 18
Pages: 5573-83
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Publication
9115210 | J:40166
First Author: Oro AE
Year: 1997
Journal: Science
Title: Basal cell carcinomas in mice overexpressing sonic hedgehog.
Volume: 276
Issue: 5313
Pages: 817-21
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Publication
34948179 | J:316844
 
First Author: Ragab N
Year: 2021
Journal: Int J Mol Sci
Title: Oncogenic NRAS Accelerates Rhabdomyosarcoma Formation When Occurring within a Specific Time Frame during Tumor Development in Mice.
Volume: 22
Issue: 24
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Publication
10500113 | J:113791
First Author: Fuse N
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Sonic hedgehog protein signals not as a hydrolytic enzyme but as an apparent ligand for patched.
Volume: 96
Issue: 20
Pages: 10992-9
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Publication
11165486 | J:67306
First Author: Koebernick K
Year: 2001
Journal: Mech Dev
Title: Molecular cloning and expression analysis of the Hedgehog receptors XPtc1 and XSmo in Xenopus laevis.
Volume: 100
Issue: 2
Pages: 303-8
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Publication
9988878 | J:52397
First Author: Koebbe MJ
Year: 1999
Journal: Teratology
Title: Effects of prenatal cocaine exposure on embryonic expression of sonic hedgehog.
Volume: 59
Issue: 1
Pages: 12-9
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Publication
10226030 | J:54463
First Author: Wallace VA
Year: 1999
Journal: Curr Biol
Title: Purkinje-cell-derived Sonic hedgehog regulates granule neuron precursor cell proliferation in the developing mouse cerebellum.
Volume: 9
Issue: 8
Pages: 445-8
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Publication
10498887 | J:58240
First Author: Merlino G
Year: 1999
Journal: Oncogene
Title: Rhabdomyosarcoma--working out the pathways.
Volume: 18
Issue: 38
Pages: 5340-8
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Publication
11973281 | J:75942
First Author: Ybot-Gonzalez P
Year: 2002
Journal: Development
Title: Sonic hedgehog and the molecular regulation of mouse neural tube closure.
Volume: 129
Issue: 10
Pages: 2507-17
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Publication
12592614 | J:82151
First Author: Ioannides AS
Year: 2003
Journal: J Pediatr Surg
Title: Role of Sonic hedgehog in the development of the trachea and oesophagus.
Volume: 38
Issue: 1
Pages: 29-36; discussion 29-36
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Publication
20624968 | J:162568
First Author: Kim J
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Arsenic antagonizes the Hedgehog pathway by preventing ciliary accumulation and reducing stability of the Gli2 transcriptional effector.
Volume: 107
Issue: 30
Pages: 13432-7
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Publication
22679284 | J:185599
First Author: Fombonne J
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Patched dependence receptor triggers apoptosis through ubiquitination of caspase-9.
Volume: 109
Issue: 26
Pages: 10510-5
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Publication
22864913 | J:188611
First Author: Wu VM
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Small molecule inhibitors of Smoothened ciliary localization and ciliogenesis.
Volume: 109
Issue: 34
Pages: 13644-9
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Publication
27162362 | J:232172
 
First Author: Sever N
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Endogenous B-ring oxysterols inhibit the Hedgehog component Smoothened in a manner distinct from cyclopamine or side-chain oxysterols.
Volume: 113
Issue: 21
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Publication
28793263 | J:254868
First Author: Lettice LA
Year: 2017
Journal: Cell Rep
Title: The Conserved Sonic Hedgehog Limb Enhancer Consists of Discrete Functional Elements that Regulate Precise Spatial Expression.
Volume: 20
Issue: 6
Pages: 1396-1408
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Publication
25871385 | J:316503
First Author: Brennan-Crispi DM
Year: 2015
Journal: Oncotarget
Title: Crosstalk between Desmoglein 2 and Patched 1 accelerates chemical-induced skin tumorigenesis.
Volume: 6
Issue: 11
Pages: 8593-605
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Publication
28127049 | J:316170
First Author: Agrawal V
Year: 2017
Journal: Exp Mol Med
Title: Hhip regulates tumor-stroma-mediated upregulation of tumor angiogenesis.
Volume: 49
Issue: 1
Pages: e289
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Publication
38233525 | J:350007
First Author: Lim F
Year: 2024
Journal: Nature
Title: Affinity-optimizing enhancer variants disrupt development.
Volume: 626
Issue: 7997
Pages: 151-159
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Publication
16887337 | J:113291
First Author: Morita K
Year: 2006
Journal: J Dermatol Sci
Title: HAN11 binds mDia1 and controls GLI1 transcriptional activity.
Volume: 44
Issue: 1
Pages: 11-20
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Publication
10526153 | J:58089
First Author: Tisljar K
Year: 1999
Journal: FEBS Lett
Title: Cathepsin J, a novel murine cysteine protease of the papain family with a placenta-restricted expression.
Volume: 459
Issue: 3
Pages: 299-304
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Publication
21177534 | J:203400
First Author: He Z
Year: 2011
Journal: J Biol Chem
Title: A novel KRAB domain-containing zinc finger transcription factor ZNF431 directly represses Patched1 transcription.
Volume: 286
Issue: 9
Pages: 7279-89
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Publication
19733558 | J:154375
First Author: Ng A
Year: 2009
Journal: Dev Biol
Title: Loss of glypican-3 function causes growth factor-dependent defects in cardiac and coronary vascular development.
Volume: 335
Issue: 1
Pages: 208-15
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Publication
16020517 | J:100425
First Author: Grobe K
Year: 2005
Journal: Development
Title: Cerebral hypoplasia and craniofacial defects in mice lacking heparan sulfate Ndst1 gene function.
Volume: 132
Issue: 16
Pages: 3777-86
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Publication
9462734 | J:45907
First Author: Motoyama J
Year: 1998
Journal: Nat Genet
Title: Ptch2, a second mouse Patched gene is co-expressed with Sonic hedgehog.
Volume: 18
Issue: 2
Pages: 104-6
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Publication
8595881 | J:31336
First Author: Goodrich LV
Year: 1996
Journal: Genes Dev
Title: Conservation of the hedgehog/patched signaling pathway from flies to mice: induction of a mouse patched gene by Hedgehog.
Volume: 10
Issue: 3
Pages: 301-12
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Publication
16702471 | J:122447
First Author: Asai J
Year: 2006
Journal: Circulation
Title: Topical sonic hedgehog gene therapy accelerates wound healing in diabetes by enhancing endothelial progenitor cell-mediated microvascular remodeling.
Volume: 113
Issue: 20
Pages: 2413-24
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Publication
18351672 | J:132977
First Author: McGlinn E
Year: 2008
Journal: Dev Dyn
Title: Expression of the NET family member Zfp503 is regulated by hedgehog and BMP signaling in the limb.
Volume: 237
Issue: 4
Pages: 1172-82
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Publication
11090455 | J:65900
First Author: Clark AM
Year: 2000
Journal: Biol Reprod
Title: Desert hedgehog (Dhh) gene is required in the mouse testis for formation of adult-type Leydig cells and normal development of peritubular cells and seminiferous tubules.
Volume: 63
Issue: 6
Pages: 1825-38
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28709001 | J:272654
First Author: Kopinke D
Year: 2017
Journal: Cell
Title: Ciliary Hedgehog Signaling Restricts Injury-Induced Adipogenesis.
Volume: 170
Issue: 2
Pages: 340-351.e12
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25531316 | J:224247
First Author: Lindsey JC
Year: 2015
Journal: Oncogene
Title: Cross-species epigenetics identifies a critical role for VAV1 in SHH subgroup medulloblastoma maintenance.
Volume: 34
Issue: 36
Pages: 4746-57
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Publication
20581804 | J:163390
First Author: Po A
Year: 2010
Journal: EMBO J
Title: Hedgehog controls neural stem cells through p53-independent regulation of Nanog.
Volume: 29
Issue: 15
Pages: 2646-58
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Publication
26363008 | J:226786
First Author: Ng JM
Year: 2015
Journal: Cancer Res
Title: Generation of a mouse model of atypical teratoid/rhabdoid tumor of the central nervous system through combined deletion of Snf5 and p53.
Volume: 75
Issue: 21
Pages: 4629-39
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Publication
24684846 | J:210811
First Author: Morfouace M
Year: 2014
Journal: Cancer Cell
Title: Pemetrexed and gemcitabine as combination therapy for the treatment of Group3 medulloblastoma.
Volume: 25
Issue: 4
Pages: 516-29
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Publication
33789113 | J:306567
First Author: Dang MT
Year: 2021
Journal: Cell Rep
Title: Macrophages in SHH subgroup medulloblastoma display dynamic heterogeneity that varies with treatment modality.
Volume: 34
Issue: 13
Pages: 108917
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16260494 | J:102702
First Author: Uziel T
Year: 2005
Journal: Genes Dev
Title: The tumor suppressors Ink4c and p53 collaborate independently with Patched to suppress medulloblastoma formation.
Volume: 19
Issue: 22
Pages: 2656-67
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Publication
17452975 | J:125534
First Author: Lee Y
Year: 2007
Journal: Oncogene
Title: Loss of suppressor-of-fused function promotes tumorigenesis.
Volume: 26
Issue: 44
Pages: 6442-7
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Publication
31300449 | J:294670
First Author: Du F
Year: 2019
Journal: Clin Cancer Res
Title: Leukotriene Synthesis Is Critical for Medulloblastoma Progression.
Volume: 25
Issue: 21
Pages: 6475-6486
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Publication
26319366 | J:227665
 
First Author: Noguchi KK
Year: 2015
Journal: Neurobiol Dis
Title: Hedgehog regulates cerebellar progenitor cell and medulloblastoma apoptosis.
Volume: 83
Pages: 35-43
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Publication
19185848 | J:144811
First Author: Read TA
Year: 2009
Journal: Cancer Cell
Title: Identification of CD15 as a marker for tumor-propagating cells in a mouse model of medulloblastoma.
Volume: 15
Issue: 2
Pages: 135-47
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Publication
39137728 | J:353325
First Author: Yang Y
Year: 2024
Journal: Cancer Cell
Title: Thyroid hormone suppresses medulloblastoma progression through promoting terminal differentiation of tumor cells.
Volume: 42
Issue: 8
Pages: 1434-1449.e5
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Publication
29474906 | J:257438
First Author: Garzia L
Year: 2018
Journal: Cell
Title: A Hematogenous Route for Medulloblastoma Leptomeningeal Metastases.
Volume: 172
Issue: 5
Pages: 1050-1062.e14
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Publication
27815529 | J:238842
First Author: Lee JJ
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Control of inflammation by stromal Hedgehog pathway activation restrains colitis.
Volume: 113
Issue: 47
Pages: E7545-E7553
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Publication
32097463 | J:289658
 
First Author: Francisco MA
Year: 2020
Journal: J Exp Med
Title: Chloride intracellular channel 1 cooperates with potassium channel EAG2 to promote medulloblastoma growth.
Volume: 217
Issue: 5
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Publication
36323321 | J:332396
First Author: Chen X
Year: 2023
Journal: Neuron
Title: Mechanosensitive brain tumor cells construct blood-tumor barrier to mask chemosensitivity.
Volume: 111
Issue: 1
Pages: 30-48.e14
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Publication
23371063 | J:211755
First Author: Liu L
Year: 2013
Journal: Am J Respir Cell Mol Biol
Title: Hedgehog signaling in neonatal and adult lung.
Volume: 48
Issue: 6
Pages: 703-10
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Publication
23343527 | J:213333
First Author: Renault MA
Year: 2013
Journal: Circ Res
Title: Desert hedgehog promotes ischemia-induced angiogenesis by ensuring peripheral nerve survival.
Volume: 112
Issue: 5
Pages: 762-70
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Publication
30841515 | J:291286
 
First Author: Łastowska M
Year: 2019
Journal: Cells
Title: Differential Expression of Mitochondrial Biogenesis Markers in Mouse and Human SHH-Subtype Medulloblastoma.
Volume: 8
Issue: 3
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Publication
12835403 | J:84605
First Author: Jeong Y
Year: 2003
Journal: Development
Title: Distinct regulators of Shh transcription in the floor plate and notochord indicate separate origins for these tissues in the mouse node.
Volume: 130
Issue: 16
Pages: 3891-902
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23065639 | J:193730
First Author: Behesti H
Year: 2013
Journal: Dis Model Mech
Title: Bmi1 overexpression in the cerebellar granule cell lineage of mice affects cell proliferation and survival without initiating medulloblastoma formation.
Volume: 6
Issue: 1
Pages: 49-63
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17641202 | J:123161
First Author: Rohatgi R
Year: 2007
Journal: Science
Title: Patched1 regulates hedgehog signaling at the primary cilium.
Volume: 317
Issue: 5836
Pages: 372-6
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22330336 | J:181988
First Author: Sekiguchi H
Year: 2012
Journal: Lab Invest
Title: Estradiol triggers sonic-hedgehog-induced angiogenesis during peripheral nerve regeneration by downregulating hedgehog-interacting protein.
Volume: 92
Issue: 4
Pages: 532-42
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18347090 | J:132983
First Author: Zhao H
Year: 2008
Journal: Genes Dev
Title: Post-transcriptional down-regulation of Atoh1/Math1 by bone morphogenic proteins suppresses medulloblastoma development.
Volume: 22
Issue: 6
Pages: 722-7
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Publication
37774709 | J:341634
First Author: Pokrajac NT
Year: 2023
Journal: Dev Cell
Title: Meningeal macrophages inhibit chemokine signaling in pre-tumor cells to suppress mouse medulloblastoma initiation.
Volume: 58
Issue: 20
Pages: 2015-2031.e8
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Publication
33561442 | J:304825
   
First Author: Ohgami N
Year: 2021
Journal: J Biol Chem
Title: Loss-of-function mutation of c-Ret causes cerebellar hypoplasia in mice with Hirschsprung disease and Down's syndrome.
Pages: 100389
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12648487 | J:82653
First Author: Oro AE
Year: 2003
Journal: Dev Biol
Title: Hair cycle regulation of Hedgehog signal reception.
Volume: 255
Issue: 2
Pages: 238-48
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18477451 | J:135170
First Author: Mak KK
Year: 2008
Journal: Dev Cell
Title: Hedgehog signaling in mature osteoblasts regulates bone formation and resorption by controlling PTHrP and RANKL expression.
Volume: 14
Issue: 5
Pages: 674-88
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17363588 | J:120317
First Author: Zindy F
Year: 2007
Journal: Cancer Res
Title: Genetic alterations in mouse medulloblastomas and generation of tumors de novo from primary cerebellar granule neuron precursors.
Volume: 67
Issue: 6
Pages: 2676-84
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Publication
25241898 | J:224264
First Author: Brun SN
Year: 2015
Journal: Oncogene
Title: Survivin as a therapeutic target in Sonic hedgehog-driven medulloblastoma.
Volume: 34
Issue: 29
Pages: 3770-9
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39138140 | J:353362
First Author: Walker MF
Year: 2024
Journal: PLoS Biol
Title: GRK2 kinases in the primary cilium initiate SMOOTHENED-PKA signaling in the Hedgehog cascade.
Volume: 22
Issue: 8
Pages: e3002685
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Publication
30291846 | J:294443
First Author: Brennan-Crispi DM
Year: 2019
Journal: J Invest Dermatol
Title: Overexpression of Desmoglein 2 in a Mouse Model of Gorlin Syndrome Enhances Spontaneous Basal Cell Carcinoma Formation through STAT3-Mediated Gli1 Expression.
Volume: 139
Issue: 2
Pages: 300-307
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Publication
22661232 | J:184827
First Author: Woo WM
Year: 2012
Journal: Genes Dev
Title: Shh maintains dermal papilla identity and hair morphogenesis via a Noggin-Shh regulatory loop.
Volume: 26
Issue: 11
Pages: 1235-46
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26219237 | J:226455
     
First Author: Zhang H
Year: 2015
Journal: Genesis
Title: Generation of Evc2/Limbin global and conditional KO mice and its roles during mineralized tissue formation.
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30554998 | J:272598
First Author: Yin WC
Year: 2019
Journal: Dev Cell
Title: Dual Regulatory Functions of SUFU and Targetome of GLI2 in SHH Subgroup Medulloblastoma.
Volume: 48
Issue: 2
Pages: 167-183.e5
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12587916 | J:81440
First Author: Crick AP
Year: 2003
Journal: J Anat
Title: Developmental mechanisms underlying polydactyly in the mouse mutant Doublefoot.
Volume: 202
Issue: 1
Pages: 21-6
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24141783 | J:214349
First Author: Chan LH
Year: 2014
Journal: Oncogene
Title: Hedgehog signaling induces osteosarcoma development through Yap1 and H19 overexpression.
Volume: 33
Issue: 40
Pages: 4857-66
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15475264 | J:93364
First Author: Hahn H
Year: 2004
Journal: Genomics
Title: Genetic mapping of a Ptch1-associated rhabdomyosarcoma susceptibility locus on mouse chromosome 2.
Volume: 84
Issue: 5
Pages: 853-8
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12869303 | J:85011
First Author: Rao G
Year: 2003
Journal: Neoplasia
Title: c-Myc enhances sonic hedgehog-induced medulloblastoma formation from nestin-expressing neural progenitors in mice.
Volume: 5
Issue: 3
Pages: 198-204
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Publication
29254138 | J:272340
First Author: Tanori M
Year: 2017
Journal: Oncotarget
Title: Synthetic lethal genetic interactions between Rad54 and PARP-1 in mouse development and oncogenesis.
Volume: 8
Issue: 60
Pages: 100958-100974
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Publication
17115028 | J:346494
First Author: Di Marcotullio L
Year: 2006
Journal: Nat Cell Biol
Title: Numb is a suppressor of Hedgehog signalling and targets Gli1 for Itch-dependent ubiquitination.
Volume: 8
Issue: 12
Pages: 1415-23
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Publication
21602895 | J:178573
First Author: Tanori M
Year: 2011
Journal: Oncogene
Title: Opposite modifying effects of HR and NHEJ deficiency on cancer risk in Ptc1 heterozygous mouse cerebellum.
Volume: 30
Issue: 47
Pages: 4740-9
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Publication
25452120 | J:218252
First Author: De Stefano I
Year: 2015
Journal: Am J Pathol
Title: The Patched 1 tumor-suppressor gene protects the mouse lens from spontaneous and radiation-induced cataract.
Volume: 185
Issue: 1
Pages: 85-95
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Publication
23897709 | J:204015
First Author: Tanori M
Year: 2013
Journal: Stem Cells
Title: Developmental and oncogenic radiation effects on neural stem cells and their differentiating progeny in mouse cerebellum.
Volume: 31
Issue: 11
Pages: 2506-16
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Publication
30606609 | J:294551
 
First Author: Tanori M
Year: 2019
Journal: DNA Repair (Amst)
Title: Cancer risk from low dose radiation in Ptch1+/- mice with inactive DNA repair systems: Therapeutic implications for medulloblastoma.
Volume: 74
Pages: 70-79
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Publication
17525797 | J:122159
First Author: Seppala M
Year: 2007
Journal: J Clin Invest
Title: Gas1 is a modifier for holoprosencephaly and genetically interacts with sonic hedgehog.
Volume: 117
Issue: 6
Pages: 1575-84
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Publication
22792366 | J:189643
First Author: Maezawa Y
Year: 2012
Journal: PLoS One
Title: A new Cre driver mouse line, Tcf21/Pod1-Cre, targets metanephric mesenchyme.
Volume: 7
Issue: 7
Pages: e40547
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Publication
12615071 | J:82558
First Author: Ohuchi H
Year: 2003
Journal: Biochem Biophys Res Commun
Title: Fibroblast growth factor 10 is required for proper development of the mouse whiskers.
Volume: 302
Issue: 3
Pages: 562-7
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Publication
32645357 | J:294224
First Author: Gredler ML
Year: 2020
Journal: Dev Biol
Title: Foxa1 and Foxa2 orchestrate development of the urethral tube and division of the embryonic cloaca through an autoregulatory loop with Shh.
Volume: 465
Issue: 1
Pages: 23-30
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Publication
19906862 | J:154980
First Author: Seifert AW
Year: 2009
Journal: Development
Title: Multiphasic and tissue-specific roles of sonic hedgehog in cloacal septation and external genitalia development.
Volume: 136
Issue: 23
Pages: 3949-57
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Publication
33082319 | J:298098
First Author: Ong T
Year: 2020
Journal: Nat Commun
Title: Siah2 integrates mitogenic and extracellular matrix signals linking neuronal progenitor ciliogenesis with germinal zone occupancy.
Volume: 11
Issue: 1
Pages: 5312
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Publication
35508126 | J:325007
First Author: Trieu KG
Year: 2022
Journal: Cell Rep
Title: Basal cell carcinomas acquire secondary mutations to overcome dormancy and progress from microscopic to macroscopic disease.
Volume: 39
Issue: 5
Pages: 110779
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Publication
30297799 | J:266587
First Author: Sánchez-Danés A
Year: 2018
Journal: Nature
Title: A slow-cycling LGR5 tumour population mediates basal cell carcinoma relapse after therapy.
Volume: 562
Issue: 7727
Pages: 434-438
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Publication
19213072 | J:159972
First Author: Taniguchi E
Year: 2009
Journal: Pediatr Blood Cancer
Title: Bortezomib reverses a post-translational mechanism of tumorigenesis for patched1 haploinsufficiency in medulloblastoma.
Volume: 53
Issue: 2
Pages: 136-44
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Publication
30503211 | J:269586
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